Molecular typing of listeria monocytogenes, hybridization supports and kits for said molecular typing

ABSTRACT

This invention provides 163 genes that are unique to the  L. monocytogenes  serovar 4b strain, CLIP80459, compared with  L. monocytogenes  EGDe strain. These genes are the basis for isolated nucleic acids, hybridization supports, and kits comprising a nucleotide sequence that is unique to a serovar 4b strain of  L. monocytogenes.  The invention also provides methods for identifying a  L. monocytogenes  in a sample, methods for identifying the lineage of a  L. monocytogenes  in a sample, and methods for sub-lineage typing of a  L. monocytogenes  in a sample. The invention also provides hybridization supports comprising a  L. monocytogenes  lineage-specific nucleic acid sequence, hybridization supports comprising a  L. monocytogenes  sub-lineage-specific nucleic acid sequence combination, and kits comprising a nucleic acid or hybridization support of the invention. Additionally, the invention provides specific macroarrays, methods, and kits for use in serotyping  L. monocytogenes.

This application is a continuation-in-part of application Ser. No. 11/154,929, filed Jun. 17, 2005, which is a continuation of application Ser. No. 10/942,074, filed Sep. 16, 2004, which claims priority to Provisional Application No. 60/502,935, filed Sep. 16, 2003. The entire disclosure of each of these priority applications is hereby incorporated herein by reference for all purposes.

BACKGROUND OF THE INVENTION

The sequencing of complete microbial genomes has revealed insights into the genetic structure of a number of bacterial species. However, it has become evident that the genome sequence of one strain is not entirely representative for other members of the species, and that the broad spectrum of physiological and virulence properties of bacterial pathogens mirrors the existence of different subsets of genes enabling different lifestyles. In addition to whole genome comparisons (1, 2), micro- and macro-array techniques are extensively used to study inter- and intra-species diversity of bacterial pathogens (3, 4). These studies suggest that, although considerable diversity is present among different bacterial isolates of the same species, clonal expansion of highly virulent sub-populations of a bacterial pathogen may exist.

L. monocytogenes, an intracellular pathogen, is the causative agent of serious epidemic and sporadic food-borne listeriosis. The clinical features of listeriosis include meningitis, meningo-encephalitis, septicemia, abortion, perinatal infections and gastroenteritis (5). Although rare when compared to other food-borne diseases, a significant feature of listeriosis is the high lethality rate (about 30%), which makes L. monocytogenes an important human pathogen. L. monocytogenes has the capacity to adapt and survive in extreme conditions, allowing it to ubiquitously exist in the environment and to survive and proliferate under conditions that exist within the food chain.

L. monocytogenes strains are commonly differentiated by the serotyping method. Serotyping of L. monocytogenes is based on the variation of fifteen somatic and five flagellar antigens, combinations of which have defined 13 different serovars of the organism (Seeliger and Höhne,1979). Interestingly, not all strains of L. monocytogenes are equally capable of causing disease in humans. Isolates from four (1/2a; 1/2c; 1/2b; 4b) of the 13 serovars (sv) identified within this species are responsible for over 98% of the human listeriosis cases reported (6). A number of different typing and population genetic studies suggested that different genetic divisions/lineages exist within the species L. monocytogenes, and correlate with serovars (7-10).

Specifically, lineage I comprises, sv 1/2a, 1/2c, and 3c, lineage II comprises sv 4b, 1/2b and 3b, and lineage III comprises sv 4a and 4c. Genetic analyses using multilocus sequence typing of virulence-associated genes, RFLP analysis and ribotyping suggested that epidemic strains are mostly found in lineage 11 and sporadic strains in lineage I and II, while lineage III strains are extremely rare and mostly animal pathogens (11, 12). However, these methods are unable to further characterize the genetic basis for this observed variability.

Numerous genotyping methods, based on the detection of DNA polymorphism, provide sensitive strain discrimination and a high level of standardization and reproducibility were developed to link a human case of listeriosis to suspect food items. The most widely used molecular methods providing highly discriminating results for L. monocytogenes include ribotyping and pulsed field gel electrophoresis (Brosch et al. 1996; Bruce et al. 1995). However, groupings based on these methods are still often compared to groupings on serotype since this nomenclature is widely used and established. Furthermore, in spite of the highly reproducible and discriminating power indispensable to tracking the contamination source in foods, ribotyping and pulsed field gel electrophoresis methods are costly or laborious and time consuming. Thus, in listeriosis outbreak investigations, subgrouping by serotyping has proven utility as a first subtyping method for practical purposes and time savings in reducing the number of suspected isolates.

However, conventional serological assays using slide agglutination to serotype L. monocytogenes isolates are complex, and require up to three days to be completed. Additionally, this assay relies on visual acuity and judgment, which may be a substantial source of variability when comparing results between individuals in a laboratory and different laboratories. In addition, the assay is difficult to automate, so that it is difficult to use this method to characterize a large number of isolates.

Recently, Zhang et al., Journal of Bacteriology, Vol.185, No.18, pp. 5573-5584 (2003), reported probing 44 strains with a DNA microarray constructed from strain 10403s.

Meanwhile, the complete genome sequences of Listeria monocytogenes strain EGDe and Listeria innocua strain CLIP11262 were determined (13). The genome sequence of Listeria monocytogenes strain EGDe (deposited at the CNCM on Apr. 11, 2000, under Accession No. I-2440) is described in FR 00/04629, filed Apr. 11, 2000. The genome sequence of Listeria innocua strain CLIP11262 (deposited at the CNCM on Oct. 2, 2000, under Accession Nos. I-2565 and I-2566) is described in FR 00/12,697, filed Oct. 4, 2000. The comparison of these sequences revealed 10.5% and 14% specific sequences for each isolate, respectively (13). L. monocytogenes strain EGDe is of sv 1/2a and belongs to lineage I. However, all major food-borne outbreaks of listeriosis, as well as the majority of sporadic cases, have been caused by serovar 4b strains, which belong to lineage II. This suggests that strains of this sv may possess unique virulence properties.

Accordingly, there exists a need in the art to provide the sequence of the genome of a serovar 4b strain of L. monocytogenes. In particular, there is a need to identify genes or markers of a serovar 4b strain which are unique relative to strain EGDe. There also exists a need to provide strain-specific genetic markers of L. monocytogenes strains and methods of using strain-specific genetic markers of L. monocytogenes strains to characterize L. monocytogenes isolates.

SUMMARY OF THE INVENTION

The inventors have met this need by providing 163 genes that are unique to the L. monocytogenes serovar 4b strain, CLIP80459, compared with L. monocytogenes EGDe strain. These genes are the basis for isolated nucleic acids, hybridization supports, and kits comprising a nucleotide sequence that is unique to the L. monocytogenes serovar 4b strain, CLIP80459, compared with L. monocytogenes EGDe strain.

The invention also provides methods for identifying a L. monocytogenes in a sample, methods for identifying the lineage of a L. monocytogenes in a sample, and methods for sub-lineage typing of a L. monocytogenes in a sample.

The invention also provides hybridization supports comprising a L. monocytogenes lineage-specific nucleic acid sequence, hybridization supports comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence combination, and kits comprising a nucleic acid or hybridization support of the invention.

In a first embodiment, the invention provides an isolated nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

In another embodiment, the invention provides a hybridization support comprising a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

In another embodiment, the invention provides a vector comprising a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

The invention also provides a recombinant cell comprising a vector comprising a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

In a further embodiment, the invention provides an isolated polypeptide comprising a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326.

In another embodiment the invention provides an isolated antibody that specifically binds to a polypeptide comprising a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326. In a preferred embodiment, the antibody is a monoclonal antibody.

In further embodiments, the invention provides a hybridization support comprising an isolated polypeptide comprising a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326. The invention also provides a hybridization support comprising an antibody that specifically binds to a polypeptide comprising a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326.

Another embodiment of the invention provides a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the method comprises detecting a nucleic acid in the sample, the nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

The invention also provides a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample. The method comprises (a) bringing the sample into contact with the hybridization support comprising a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5; and (b) detecting a specific hybrid between the hybridization support and a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

The invention further provides a method for identifying a L. monocytogenes in a sample. The method comprises detecting a L. monocytogenes-specific nucleic acid sequence in the sample. In some embodiments the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo 0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821. In further embodiments the L. monocytogenes-specific nucleic acid sequence is inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inlG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inlF, Imo320, Imo0842, Imo0801, inlG, Imo115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.

The invention further provides a method for identifying the lineage of a L. monocytogenes in a sample. The method comprises detecting the absence or the presence of a L. monocytogenes lineage-specific nucleic acid sequence in the sample. In some embodiments the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.

In further embodiments the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage III-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.

The invention also provides a method for sub-lineage typing of a L. monocytogenes in a sample. The method comprises determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample.

In some embodiments, the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises hybridizing a probe or probe combination comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence or sequences to L. monocytogenes genomic DNA obtained from the sample, and detecting a hybridization product comprising the probe or probe combination and a L. monocytogenes genomic DNA sequence.

In some embodiments the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises hybridizing a primer or primer combination comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence or sequences to L. monocytogenes genomic DNA obtained from the sample; amplifying a L. monocytogenes sub-lineage-specific fragment or fragments with a polymerase; and detecting the L. monocytogenes sub-lineage-specific fragment or fragments.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a lineage I-specific nucleic acid sequence; a sublineage I.1- or I.2-specific nucleic acid sequence; a lineage II-specific nucleic acid sequence; and a sublineage II.1- or II.2-specific nucleic acid sequence.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence.

In some embodiments the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.

In some embodiments the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119.

In some embodiments the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761.

In some embodiments the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment or variant of ORF 0799, ORF 2372 or ORF 2110.

In some embodiments the lineage I-specific nucleic acid sequence is Imo737 or a fragment thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1 -specific nucleic acid sequence is ORF 2110 or a fragment thereof.

In some embodiments, the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises (a) hybridizing a probe combination comprising i) a lineage I-specific nucleic acid sequence; ii) a sublineage I.2-specific nucleic acid sequence; iii) a lineage II-specific nucleic acid sequence; and iv) a sublineage II.1-specific nucleic acid sequence to L. monocytogenes genomic DNA obtained from the sample; and (b) detecting a hybridization product comprising the probe or probe combination and a L. monocytogenes genomic DNA sequence.

In a preferred embodiment the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1 -specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.

In some embodiments the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises (a) hybridizing a primer or primer combination comprising i) a lineage I-specific nucleic acid sequence; ii) a sublineage I.2-specific nucleic acid sequence; iii) a lineage II-specific nucleic acid sequence; and iv) a sublineage II.1-specific nucleic acid sequence to L. monocytogenes genomic DNA obtained from the sample; and (b) amplifying a L. monocytogenes sub-lineage-specific fragment or fragments with a polymerase; and (c) detecting the L. monocytogenes sub-lineage-specific fragment or fragments.

In a preferred embodiment the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.

The invention also provides a hybridization support comprising a L. monocytogenes-specific nucleic acid sequence. In some embodiments the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo 0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821. In some embodiments the L. monocytogenes-specific nucleic acid sequence is inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inlF, Imo320, Imo0842, Imo0801, inlG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inlF, Imo320, Imo0842, Imo0801, inlG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.

The invention also provides a hybridization support comprising a L. monocytogenes lineage-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973or Imo 1974.

In further embodiments the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence. In some embodiments, the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.

The invention also provides a hybridization support comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence combination.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a lineage I-specific nucleic acid sequence; a sublineage I.1- or I.2-specific nucleic acid sequence; a lineage II-specific nucleic acid sequence; and a sublineage II.1- or II.2-specific nucleic acid sequence.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence. In some embodiments the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974. In some embodiments the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119. In some embodiments the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761. In some embodiments the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment or variant of ORF 0799, ORF 2372 or ORF 2110. In a preferred embodiment, the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.

The invention also provides a kit for use in a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the kit comprises a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

The invention also provides a kit for use in a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the kit comprises a hybridization support comprising a nucleic acid comprising a nucleotide sequence selected from SEQ ID NOS: 1-163; a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table 5.

The invention further provides a kit for use in a method for identifying a L. monocytogenes in a sample, wherein the kit comprises a hybridization support comprising a L. monocytogenes-specific nucleic acid sequence, in packaged form. In some embodiments the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, plcA, actA, plcB, Imo206, inlA, inlB, Imo0440, Imo 0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inlH, inlE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821. In some embodiments the L. monocytogenes-specific nucleic acid sequence is inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inlF, Imo320, Imo0842, Imo0801, inlG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inlA, inlB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inlE, inlH, Imo2821, Imo2027, inlC, Imo0835, Imo1666, inlF, Imo320, Imo0842, Imo0801, inlG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.

The invention further provides a kit for use in a method for identifying the lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes lineage-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973or Imo 1974.

In further embodiments the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761.

In further embodiments the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence. In some embodiments the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.

The invention also provides a kit for use in a method for identifying the sub-lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes sub-lineage-specific nucleic acid sequence combination.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a lineage I-specific nucleic acid sequence a sublineage I.1- or I.2-specific nucleic acid sequence; a lineage II-specific nucleic acid sequence; and a sublineage II.1- or II.2-specific nucleic acid sequence.

In some embodiments the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence. In some embodiments the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974. In some embodiments the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119. In some embodiments the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761. In some embodiments the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment of ORF 0799, ORF 2372 or ORF 2110. In a preferred embodiment the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.

The invention also provides a hybridization support comprising a probe specific for L. monocytogenes EGDe relative to L. innocua CLIP11262, a probe specific for L. innocua CLIP11262 relative to L. monocytogenes EGDe, and a probe present only in L. monocytogenes CLIP80459. In a preferred embodiment the hybridization support comprises 262 probes specific for L. monocytogenes EGDe relative to L. innocua CLIP11262 and all virulence genes, 94 probes specific for L. innocua CLIP11262 relative to L. monocytogenes EGDe, and 53 probes present only in L. monocytogenes CLIP80459.

In a further preferred embodiment the hybridization support comprises the 409 probes listed in Table 7, or fragments or variants thereof.

In a further preferred embodiment the hybridization support comprises the 192 probes listed in Table 16, or fragments or variants thereof.

The invention also provides a method of serotyping a L. monocytogenes. The method comprises providing a sample comprising an L. monocytogenes of unknown serotype; providing an amplification primer pair for amplification of a 1/2a-1/2c-specific nucleic acid sequence; providing an amplification primer pair for amplification of a 1/2b-4b-specific nucleic acid sequence; providing an amplification primer pair for amplification of a 1/2c nucleic acid sequence; providing an amplification primer pair for amplification of a 4b nucleic acid sequence; performing an amplification reaction on the sample; and detecting the presence of any amplification products formed during the amplification reaction to thereby serotype the L. monocytogenes.

In some embodiments the 1/2a-1/2c-specific nucleic acid sequence is selected from Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 and Imo1974. In a preferred embodiment the 1/2a-1/2c-specific nucleic acid sequence is Imo737.

In some embodiments the 1/2b-4b-specific nucleic acid sequence is selected from ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761. In a preferred embodiment the 1/2b-4b-specific nucleic acid sequence is ORF 2819.

In some embodiments the 1/2c nucleic acid sequence is selected from Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 and Imo1119. In a preferred embodiment the 1/2c nucleic acid sequence is Imo1119.

In some embodiments the 4b nucleic acid sequence is selected from ORF 799, ORF 2372 and ORF 2110. In a preferred embodiment the 4b nucleic acid sequence is ORF 2110.

In a further preferred embodiment, the 1/2a-1/2c-specific nucleic acid sequence is Imo737, the 1/2b-4b-specific nucleic acid sequence is ORF 2819, the 1/2c nucleic acid sequence is Imo1119, and the 4b nucleic acid sequence is ORF 2110.

The invention also provides a kit for use in serotyping a L. monocytogenes. The kit comprises an amplification primer pair for amplification of a 1/2a-1/2c-specific nucleic acid sequence; an amplification primer pair for amplification of a 1/2b-4b-specific nucleic acid sequence; an amplification primer pair for amplification of a 1/2c nucleic acid sequence; and an amplification primer pair for amplification of a 4b nucleic acid sequence.

In some embodiments the 1/2a-1/2c-specific nucleic acid sequence is selected from Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973and Imo1974. In a preferred embodiment the 1/2a-1/2c-specific nucleic acid sequence is Imo737.

In some embodiments the 1/2b-4b-specific nucleic acid sequence is selected from ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761. In a preferred embodiment the 1/2b-4b-specific nucleic acid sequence is ORF 2819.

In some embodiments the 1/2c nucleic acid sequence is selected from Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118and Imo1119. In a preferred embodiment the 1/2c nucleic acid sequence is Imo1119.

In some embodiments the 4b nucleic acid sequence is selected from ORF 799, ORF 2372 and ORF 2110. In a preferred embodiment the 4b nucleic acid sequence is ORF 2110.

In a particularly preferred embodiment, the 1/2a-1/2c-specific nucleic acid sequence is Imo737, the 1/2b-4b-specific nucleic acid sequence is ORF 2819, the 1/2c nucleic acid sequence is Imo1119, and the 4b nucleic acid sequence is ORF 2110.

The invention also provides a method for sub-lineage typing of a L. monocytogenes in a sample, wherein the method comprises detecting the absence or presence of a L. monocytogenes sub-lineage specific nucleic acid sequence in the sample. In some embodiments the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence. In a preferred embodiment the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.

The invention also provides a hybridization support comprising a L. monocytogenes sub-lineage specific nucleic acid sequence. In some embodiments the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence. In a preferred embodiment the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.

The invention also provides a kit for use in a method for identifying the lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes sub-lineage specific nucleic acid sequence. In some embodiments the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence. In a preferred embodiment the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.

The invention also provides a method of designing a hybridization support for typing Listeria. The method comprises determining at least one combination of Listeria species, strains, lineages, or sublineages to be distinguished; and selecting a plurality of probes from Table 17, based on the data presented in Table 17, for inclusion in the hybridization support.

BRIEF DESCRIPTION OF THE DRAWINGS

This invention will be more fully described with reference to the drawings, in which:

FIG. 1 shows Listeria genetic diversity. Red and black denote presence and absence of genes, respectively. A) The dendrogram shows estimates of genomic relationships of the 113 strains constructed by hierarchical cluster analysis with the program J-Express. Phylogenetic lineages and subgroups are indicated. B) Enlargements represent the blocs of lineage specific genes whose numbers are indicated on the right hand side. I: lineage I (sv 1/2a; 1/2c, 3a, 3c); II: lineage II (sv 4b, 4d, 4e, 1/2b, 3b); III: lineage III (sv 4a, 4c); I.1: sv 1/2a, 3a; I.2: sv 1/2, 3C; II.1: sv 4b, 4d, 4e; II.2: sv 1/2b, 3b.

FIG. 2 shows an evolutionary scheme of the different lineages and serovars of L. monocytogenes.

FIG. 3 shows a phylogenetic tree of L. monocytogenes serovar 4b strains. The phylogenetic tree was constructed based on gene presence and absence using the program MVSP3.1. Numbers correspond to strains whose charcteristics are given in Table 2. Epi indicates epidemic strain isolated from humans or the incriminated food source.

FIG. 4 shows PCR products obtained from serotyping reference strains of L. monocytogenes and other Listeria genus species in a multiplex PCR assay. L. monocytogenes serotype 1/2a (Lane 1); L. monocytogenes serotype 1/2b (Lane 2); L. monocytogenes serotype 1/2c (Lane 3); L. monocytogenes serotype 3a (Lane 4); L. monocytogenes serotype 3b (Lane 5); L. monocytogenes serotype 3c (Lane 6); L. monocytogenes serotype 4a (Lane 7); L. monocytogenes serotype 4b (Lane 8); L. monocytogenes serotype 4c (Lane 9); L. monocytogenes serotype 4e (Lane 10); L. monocytogenes serotype 7 (Lane 11); L. innocua (Lane 12); L. welshimeri (Lane 13); L. ivanovii (Lane 14); L. seeligeri (Lane 15); L. monocytogenes serotype 4d (Lane 16). Lane M: SmartLadder SF molecular weight marker. The sizes in bp are indicated on the left.

FIG. 5 shows sequence alignment of junction regions.

DETAILED DESCRIPTION OF THE INVENTION

One of the first criteria developed to subdivide species of L. monocytogenes was the varying antigenic properties of distinct subpopulations. A scheme developed by Seeliger and Höhne described 13 serovars (18). Based on somatic antigens L. monocytogenes isolates were divided mainly into serogroups 1/2 and 4, and based on flagellar antigen combinations, each of these serogroups was subdivided into serovars 1/2a, b, c, and 4b or some other less common serovars (18). Today, this scheme is still in use and numerous studies have identified correlations between certain phenotypic or genetic features and specific serovars (7, 8, 10, 19). The combined analysis of the genome sequences of L. monocytogenes sv 1/2a, L. innocua (13), and the partial genome sequence of L. monocytogenes sv 4b and macroarray hybridizations of 113 Listeria DNAs described herein, substantiated this classification at the genomic level.

One of the most striking observations disclosed herein is the magnitude of divergence that exists within the species L. monocytogenes. The inventors have found that the genetic divergence between lineage I and lineage II of L. monocytogenes was nearly equally important (about 6%) as the inter-species differences between the sequenced L. monocytogenes EGDe sv 1/2a strain and L. innocua (10%). These results are in line with a previous report (20), which identified 39 specific gene fragments for the epidemic L. monocytogenes strain F.4565 as compared to L. monocytogenes EGDe using a subtractive hybridization method. This is of particular importance since strains of sv 4b mainly represent epidemic L. monocytogenes strains and are isolated from severe, invasive human cases more frequently than strains of other serovars, for example sv 1/2a. Apart from the important divergence between the two lineages of L. monocytogenes, the macroarray results identified a remarkable genomic conservation within the major lineages and subgroups (FIG. 1), but variations between the different subgroups. These results seem to mirror the evolution within the genus Listeria.

An important gene family in L. monocytogenes encodes surface proteins (13, 21). The macroarray hybridization data and the analysis of the partial L. monocytogenes sv 4b sequence described herein indicate that a group of surface proteins is highly specific for the species L. monocytogenes, which includes all previously known internalin genes (inlA, inlB, inlG, inlH, inlE, inlC, inlF). Furthermore, each sub-group of L. monocytogenes is characterized by a specific set of surface proteins. Finally, a third group of surface protein-coding genes is distributed quite heterogeneously among the different Listeria species. Interestingly, in the rarely isolated L. monocytogenes sv 4a strains, which are mostly of animal origin, 13 of the 25 L. monocytogenes specific surface proteins, including all internalins except inlAB, were missing. The lack of these proteins may be related to their lower disease potential in humans. The fact that different subgroups of L. monocytogenes strains contain different sets of surface proteins may also reflect their different potential to cause disease or to multiply in different niches. The elucidation of the functions of the different surface proteins and the putative strain specific characters they confer will be one of the challenging questions for the future and may give additional insights to understand the tropism of L. monocytogenes toward different cell types.

Proteins implicated in sugar transport and metabolism, in particular PTS systems, are another important gene family in Listeria (13). Analysis of the distribution of these genes again underlined the genetic divergence of the different sub-groups in L. monocytogenes, as each lineage was characterized by a specific set of PTS permeases. Most PTS genes present in sv 1/2a, 1/2c, 3a, and 3c strains and missing in L. innocua, were also missing in the sv 4b and 1/2b strains. The finding that the bvrABC locus, a β-glucoside specific PTS system, previously described as being implicated in virulence gene expression (14), was absent from all L. monocytogenes strains of lineage II (4b, 4d, 4e, 7, 1/2b, 3b) was surprising. As regulation of the PrfA regulon by β-glucosides also takes place in lineage II strains it can be assumed that another PTS system fulfills the functions of the bvrABC proteins. The finding that one of the PTS permeases identified in the sequence of the L. monocytogenes 4b strain was present in all strains where the bvrABC locus was lacking might be consistent with this hypothesis.

The inventors have identified 30 markers for the species L. monocytogenes (Table 9), as well as markers of each sub-population within the species L. monocytogenes (Table 10). One of the major questions is whether the pronounced differences in virulence among different subgroups of strains can be explained by different gene content. The results described herein revealed that known virulence genes (inlAB, prfA, plcA, hly, mpl, actA, plcB, uhpT and bsh) are present in all L. monocytogenes strains tested. However, analysis of the correlation between epidemiological data, origin of the strains, and the genomic profile clustered the L. monocytogenes sv 4b strains isolated from epidemics and the incriminated food source, in a group separate from the other environmental, food, or animal isolates (FIG. 2). Thus, disease related L. monocytogenes seem to be characterized by a particular combination of genes and the Listeria array combined with the knowledge of the marker genes identified in this study should prove as a powerful tool for identifying these strains. Examples of oligonucleotide pairs that can be used to amplify the marker genes are provided in Tables 14 and 15.

As shown in FIG. 1, the combined use of bioinformatics and macroarray results of 113 Listeria strains generated a large dataset, whose detailed analysis allows us to group strains according to shared genetic profiles. In addition to conclusions concerning genetics, epidemiology, and virulence of Listeria, these data also allow hypotheses regarding how the different Listeria species and phylogenetic lineages may have evolved. Several studies, analyzing the 16S and 23S rRNA (22, 23), PCR-based DNA fingerprinting techniques (24), or virulence locus and genome comparisons (5, 13, 25) indicated a phylogenetically close relationship between L. monocytogenes and L. innocua and suggested that L. innocua lost the virulence locus by deletion. Most interestingly, the inventors identified several other regions missing from L. monocytogenes sv 4a strains, which were also missing from L. innocua, like the inlGHE gene cluster. Sequence analysis of the different junction regions identified identical sequences among L. monocytogenes sv 4a and the L. innocua strains, suggesting single deletion events. The presence of these genes in the other Listeria species suggests that they were part of the genome of a common ancestor and that L. innocua evolved by successive gene loss from an ancestor of L. monocytogenes serogroup 4 strains. This hypothesis is also substantiated by the similar teichoic acid structure of L. monocytogenes serogroup 4 and L. innocua strains (17) and structural and functional similarity of the cell wall anchor of the autolysin Ami of L. monocytogenes serogroup 4 and L. innocua, but divergence between Ami of L. monocytogenes sv 1/2 and sv 4 (26). Further evidence for this close relationship also comes from the antigen structure of L. monocytogenes serogroup 4 and L. innocua which exhibit the same flagellar antigen structure, different from that of sv 1/2a and 1/2c strains (18). Based on this analysis and the literature, the inventors suggest an alternative model of the evolution within the L. monocytogenes-L. innocua branch. The separation into phylogenetic lineages is based on a divergence of sv 1/2c and sv 1/2b strains from a common ancestor (FIG. 2). Later in the evolution the sv 1/2b branch gained genes like for instance gtcA, which conferred serogroup-specific expression of TA-associated serotype specific antigens (27) and evolved into serogroup 4 and later on into the species L. innocua mainly by successive gene loss.

The DNA/DNA hybridization of a specific Listeria array containing genes of three different Listeria isolates showed that L. monocytogenes strains differ substantially in gene content. These differences are most pronounced in surface proteins and sugar metabolism, which are most likely to confer traits that provide selective advantages in the environment and the infected host. These results further provide an explanation why previous studies have found an association between various characteristics of L. monocytogenes and serovars. Thus, the inventors have demonstrated that this association is due to an evolutionary differentiation. To date, the microbiological surveillance of listeriosis, a disease that causes the death of at least 400-500 persons per year in Europe and North America, is based on subtyping by serotyping and pulsed-field gel electrophoresis (28). The precise characterization of L. monocytogenes is essential to following long-term trends in sporadic cases, as well as to detecting clusters of cases and epidemics and to identifying their common source. As such, the selective markers for the different subpopulations are an essential contribution for the construction of rapid, accurate identification and subtyping tools, and should be a powerful tool applicable in health institutions and the food industry. Finally, the identification of genes consistently absent or present in epidemic-associated L. monocytogenes strains now opens the way for mutational and functional analysis of these genes in order to decipher the molecular basis for the increased pathogenic potential of certain L. monocytogenes strains.

The evaluation of the PCR assay on 180 Listeria isolates listed in Table 1 permitted the inventors to separate without ambiguities the four major serovars 1/2a, 1/2b, 1/2c and 4b specifically within the pathogenic L. monocytogenes thus confirming the suitability of using this method to replace conventional serotyping. With a high specificity to the species L. monocytogenes, the PCR assay provides an additional species confirmation for L. monocytogenes isolates without the necessity of biochemical identification.

The PCR method described herein is preferred to conventional serotyping for its adaptability for a large scale routine analysis since at least 96 samples can be processed simultaneously, and is useful for a rapid subgroup characterization of the L. monocytogenes in the investigation of listeriosis outbreaks. Compared to standard agglutination assays, the PCR assays are faster to perform, with results obtainable within 4 to 6 hours. Furthermore, the materials used for this method are easily obtainable, while specific antisera required for traditional methods are costly and for this reason can not be widely utilized in many laboratories. The PCR assay is highly reproducible and the results are easy to interpret, and need no highly specialized expertise that may involve discrepancy problems arising from interpretation variability due to visual determination of agglutinations.

Importantly, because data collected by the National Reference Centre showed that the percentage of serovars 1/2a, 1/2b, 1/2c and 4b represented over 98% of 4000 isolates collected from foods and human patients over the last three years, the PCR method described herein can identify substantially all isolates of L. monocytogenes collected from foods and human patients, even when it is not possible to provide separation between serovars 3a and 1/2a or 3c and 1/2c or 3b, 7 and 1/2b neither between 4d, 4e and 4b.

A nucleic acid is a nucleotide polymer. As used herein “nucleic acid” refers interchangeably to nucleotide polymers composed of deoxyribonucleotides, ribonucleotides, or a mixture of both. The nucleic acid may comprise modified nucleotides. Modified nucleotides include nucleotides that have been labeled with a detectable moiety, such as a fluorescent or radioactive group. The nucleic acids of the invention may be isolated form a natural source or may be synthesized chemically using well known techniques in the art.

In preferred embodiments, the nucleic acid is isolated or purified. “Isolated” or “purified” refers in relation to a nucleic acid to a nucleotide polymer in the form of a separate fragment or as a component of a larger nucleic acid construct, which has been derived from nucleic acid isolated from its natural environment at least once.

The terms “isolated” or “purified” refer to a molecule that is substantially free from its natural environment. For instance, to a nucleotide polymer in the form of a separate fragment or as a component of a larger nucleic acid construct, which has been derived from nucleic acid isolated from its natural environment at least once. An “isolated” protein is substantially free of cellular material or other contaminating proteins from the cell or tissue source from which it is derived. The phrase “substantially free of cellular material” refers to preparations where the isolated protein is at least 70% to 80% (w/w) pure, more preferably at least 80%-89% (w/w) pure, even more preferably 90-95% pure; and most preferably at least 96%, 97%, 98%, 99% or 100% (w/w) pure.

A “nucleotide sequence” is a portion of nucleic acid comprising a defined nucleotide sequence. As used herein, a reference to a particular nucleotide sequence encompasses the complement of the references sequence. A particular nucleotide sequence may comprise deoxyribonucleotides, ribonucleotides, or a mixture of both, as well as modified nucleotides. Based on this definition, it is clear to one of skill in the art that “SEQ ID NO:1” refers to SEQ ID NO:1, the complement of SEQ ID NO:1, SEQ ID NO:1 composed of deoxyribonucleotides, ribonucleotides, or a mixture of both.

A “fragment” of a nucleotide sequence is a portion less than the whole. In preferred embodiments a fragment comprises at least about 8-12 nucleotides, at least about 15-25 nucleotides, at least about 20-50 nucleotides, at least about 25-100 nucleotides, at least about 100-1000 (1 kb) nucleotides or at least about 1-5 kb.

A “variant” of a nucleotide sequence is a nucleotide sequence that exhibits, with respect to the reference nucleotide sequence, certain modifications, such as in particular a deletion, a truncation, an extension, a chimeric fusion and/or a substitution, in particular a point substitution. A variant nucleotide sequence will generally exhibit at least 75%, preferably 80%, 85%, 90%, 95% or 98%, identity, after optimal alignment, with the reference nucleic acid sequence. A variant is preferably a sequence whose complementary sequences are capable of hybridizing specifically with the reference sequence. Preferably, the specific or high stringency hybridization conditions will be such that they ensure at least 75%, preferably 80%, 85%, 90%, 95% or 98%, identity, after optimal alignment, between one of the two sequences and the sequence complementary thereto.

The term “degenerate variant” of a reference nucleic acid sequence refers to all nucleic acid sequences that can be directly translated, using the standard genetic code, to provide an amino acid sequence identical to that translated from the reference nucleic acid sequence.

Hybridization under high stringency conditions means that the conditions of temperature and of ionic strength are chosen such that they allow the hybridization between two complementary DNA fragments to be specifically maintained. By way of illustration only, one of many possible high stringency conditions in the hybridization step for the purposes of defining the polynucleotide fragments described above are advantageously as follows.

The DNA-DNA or DNA-RNA hybridization is carried out in two steps: (1) prehybridization at 42° C. for 3 hours in phosphate buffer (20 mM, pH 7.5) containing 5×SSC (1×SSC corresponds to a solution of 0.15 M NaC1 +0.015 M sodium citrate), 50% of formamide, 7% of sodium dodecyl sulfate (SDS), 10×Denhardt's, 5% of dextran sulfate and 1 % of saImon sperm DNA; (2) actual hybridization for 20 hours at a temperature which depends on the length of the probe (i.e.: 42° C. for a probe >100 nucleotides in length), followed by 2 washes for 20 minutes at 20° C. in 2×SSC +2% SDS, 1 wash for 20 minutes at 20° C. in 0.1×SSC +0.1% SDS. The final wash is carried out in 0.1×SSC +0.1 % SDS for 30 minutes at 60° C. for a probe >100 nucleotides in length. The high stringency hybridization conditions described above for a polynucleotide of defined length can be adjusted by those skilled in the art for longer or shorter oligonucleotides, according to the teaching of Sambrook et al. (1989, Molecular Cloning: a laboratory manual, 2nd Ed. Cold Spring Harbor).

The terms “polypeptide” and “protein”, used interchangebly herein, refer to a polymeric form of amino acids of any length, which can include coded and non-coded amino acids, chemically or biochemically modified or derivatized amino acids, and polypeptides having modified peptide backbones. The term includes fusion proteins, including, but not limited to, fusion proteins with a heterologous amino acid sequence, fusions with heterologous and homologous leader sequences, with or without N-terminal methionine residues; immunologically tagged proteins; and the like.

The invention also provides fragments of the subject polypeptides. In some embodiments, fragments exhibit one or more activities associated with a corresponding naturally occurring polypeptide. Fragments find utility in generating antibodies to the full-length polypeptide; and in methods of screening for candidate agents that bind to and/or modulate polypeptide activity. The term “polypeptide composition” as used herein refers to the full-length bacterial protein as well as portions or fragments thereof. Also included in this term are variations of the naturally occurring bacterial protein, where such variations are homologous or substantially similar to the naturally occurring protein, as described in greater detail below, as well as corresponding homologs from other organisms. In the following description of the subject invention, the terms “polypeptide” are used to refer not only to the L. monocytogenes serovar 4b forms of these novel polypeptides, but also to homologs thereof expressed in other organisms.

In some embodiments, a polypeptide of the invention comprises at least about 10, at least about 20, at least about 25, at least about 30, at least about 40, at least about 50, at least about 60, at least about 70, at least about 75, at least about 80, or at least about 90 contiguous amino acids of one of the sequences shown in SEQ ID NOS: 164-326, up to the entire amino acid sequence of a sequence shown in SEQ ID NOS: 164-326.

Fragments of the subject polypeptides, as well as polypeptides comprising such fragments, are also provided. Fragments of polypeptide of interest will typically be at least about 10 amino acids (aa) in length, usually at least about 50 aa in length, and may be as long as 80 aa in length or longer, where the fragment will have a stretch of amino acids that is identical to the subject protein of at least about 10 aa, and usually at least about 15 aa, and in many embodiments at least about 50 aa in length.

Specific fragments of interest include those with enzymatic activity, fragments that bind to other proteins, fragments that bind to DNA, fragments with immunogenic or antigenic properties, and the like.

The invention provides polypeptides comprising such fragments, including, e.g., fusion polypeptides comprising a subject polypeptide fragment fused in frame (directly or indirectly) to a heterologous protein. Suitable heterologous proteins include, but are not limited to, a protein that serves as a detectable marker (e.g., a fluorescent protein, β-galactosidase, luciferase); an immunologically detectable protein (e.g., an epitope tag); and a structural protein.

Polypeptide fragments, such as those described above, are useful in screening assays, to identify agents that modulate an activity of a subject polypeptide.

The term “antibody” refers to one or more polyclonal antibodies, monoclonal antibodies, antibody compositions, antibodies having mono- or poly-specificity, humanized antibodies, single-chain antibodies, chimeric antibodies, CDR-grafted antibodies, antibody fragments such as Fab, F(ab′)2, Fv, and other antibody fragments which retain the antigen binding function of the parent antibody.

The term “monoclonal antibody” refers to one or more antibodies from a substantially homogeneous antibody population. The term encompasses whole immunoglobulins, fragments such as Fab, F(ab′)2, Fv, and other fragments that retain the antigen binding function of the antibody. Monoclonal antibodies are highly specific, being directed against a single antigenic epitope.

An antibody is said to “specifically bind” or “specifically react” with a protein or peptide molecule if such binding is not competitively inhibited by the presence of non-related molecules (e.g., bovine serum albumin).

Antibodies are usually heterotetrameric glycoproteins of about 150,000 daltons, composed of two identical light (L) chains and two identical heavy (H) chains. Each light chain is linked to a heavy chain by one covalent disulfide bond, while the number of disulfide linkages varies among the heavy chains of different immunoglobulin isotypes. Each heavy and light chain also has regularly spaced intrachain disulfide bridges. Each heavy chain has at one end a variable domain (VH) followed by a number of constant domains. Each light chain has a variable domain at one end (VL) and a constant domain at its other end; the constant domain of the light chain is aligned with the first constant domain of the heavy chain, and the light-chain variable domain is aligned with the variable domain of the heavy chain. Particular amino acid residues are believed to form an interface between the light- and heavy-chain variable domains (Clothia et al. (1985) J. Mol. Biol., 186: 651-663); Novotny and Haber (1985) Proc. Natl. Acad. Sci. USA, 82: 4592-4596).

Depending on the amino acid sequence of the constant domain of their heavy chains, immunoglobulins can be assigned to different classes. There are five major classes of immunoglobulins: IgA, IgD, IgE, IgG, and IgM, and several of these may be further divided into subclasses (isotypes), e.g., IgGl, IgG2, IgG3, IgG4, IgA, and IgA2. The heavy-chain constant domains that correspond to the different classes of immunoglobulins are called a, d, e, g, and m, respectively. The subunit structures and three-dimensional configurations of different classes of immunoglobulins are well known in the art.

Antibodies may be raised against any portion of a protein which provides an antigenic epitope. The presently disclosed antibodies preferably bind to an epitope on a polypeptide sequence selected from SEQ ID NOS: 164-326; and more preferably from a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326.

A “hybridization support” is any substrate that a nucleic acid, polypeptide, or antibody of the invention may be attached to for use in an assay comprising a hybridization step. A hybridization support can be porous or solid, planar or non-planar, unitary or distributed. The bond between the nucleic acid or polypeptide and the substrate can be covalent or non-covalent.

Hybridization supports include, but are not limited to, a membrane, such as nitrocellulose, nylon, positively-charged derivatized nylon; a solid substrate such as glass, amorphous silicon, crystalline silicon, plastics (including e.g., polymethylacrylic, polyethylene, polypropylene, polyacrylate, polymethylmethacrylate, polyvinylchloride, polytetrafluoroethylene, polystyrene, polycarbonate, polyacetal, polysulfone, cellulose acetate, or mixtures thereof).

Nucleic acids, polypeptides, and antibodies of the invention can be attached covalently a surface of the hybridization support or applied to a derivatized surface in a chaotropic agent that facilitates denaturation and adherence, e.g., by noncovalent interactions, or some combination thereof.

In a preferred embodiment, a hybridization support of the invention comprises multiple nucleic acids or polypeptides of the invention attached to a single support, such as a single piece of nitrocellulose membrane or a single glass slide, in an array format, each nucleic acid having a unique physical location on the hybridization support. Such arrays differ mainly by their size, the material of the support and, optionally, the number of nucleic acids which are attached thereto.

The present invention provides vectors comprising a nucleic acid of the invention. In embodiments, the vectors are recombinant expression vectors to amplify a nucleic acid of the invention and/or to express a polypeptide product encoded by a nucleic acid of the invention. Recombinant expression vectors are replicable nucleic acid constructs that have a nucleic acid of the invention, the ability to replicate in a host, usually conferred by an origin of replication, and a selection gene to facilitate recognition of transformants.

A recombinant cell comprising a vector of the invention is a cell that has been transduced or transfected with the vector using recombinant DNA techniques. Suitable host cells include prokaryotes, yeast, or higher eukaryotic cells under the control of appropriate promoters. Prokaryotes include gram-negative or gram-positive organisms, for example E. coli or bacilli. Higher eukaryotic cells include established cell lines of mammalian origin.

A nucleic acid is detected in a sample when its presence is determined. For example, a nucleic acid may be identified by hybridizing a first nucleic acid having a first nucleotide sequence to the sample, and determining whether the first nucleotide sequence forms a hybrid with a complementary nucleotide sequence of a nucleic acid present in the sample. Because a reference to a nucleotide sequence encompasses a reference to its complement, a particular nucleotide sequence can be said to be detected through hybridization with itself.

An L. monocytogenes-specific nucleic acid is a nucleic acid comprising a nucleotide sequence present in L. monocytogenes but absent in other species of Listeria.

The “lineage” of a L. monocytogenes is a classification grouping based on the scheme set forth in Table 10. The lineages of L. monocytogenes include lineages I, II, and III.

An L. monocytogenes lineage-specific nucleic acid is a nucleic acid comprising a nucleotide sequence present in one lineage of L. monocytogenes but absent from the others (an example is ORF2819), or a nucleic acid comprising a nucleotide sequence absent in one lineage of L. monocytogenes but present in the others (an example is Imo94).

The “sub-lineage” of L. monocytogenes is a classification grouping based on the scheme set forth in Table 10. The sub-lineages of L. monocytogenes include sub-lineages I.1, I.2, II.1, II.2, III.1, and III.2.

An L. monocytogenes sub-lineage-specific nucleic acid is a nucleic acid comprising a nucleotide sequence present in one sub-lineage of a L. monocytogenes lineage, but absent from the other sub-lineage of the L. monocytogenes lineage. An example is ORF2110.

An L. monocytogenes sub-lineage-specific nucleic acid combination refers to a set of nucleic acids, the presence and/or absence of which, allows the classification of the strain of L. monocytogenes into a particular L. monocytogenes sub-lineage. For example, Imo737, Imo1119, ORF 2819, and 2110 are one such set.

“Primer” refers to a fragment of a nucleic acid sequence that is intended for use in a nucleic acid amplification reaction, such as PCR (polymerase chain reaction) technique (Rolfs et al., 1991, Berlin: Springer-Verlag). This technique requires the choice of pairs of oligonucleotide primers framing the fragment which must be amplified. Such a pair is referred to as an “amplification primer pair.” Reference may, for example, be made to the technique described in U.S. Pat. No. 4,683,202. The amplified fragments can be identified, for example after agarose or polyacrylamide gel electrophoresis or after a chromatographic technique such as gel filtration or ion exchange chromatography, and then sequenced. The amplified nucleotide fragments can be used as reagents in hybridization reactions in order to demonstrate the presence, in a biological sample, of a target nucleic acid of sequence complementary to that of said amplified nucleotide fragments.

The invention is also directed toward the nucleic acids which can be obtained by amplification using primers according to the invention.

Other techniques for amplifying a target nucleic acid can advantageously be used as an alternative to a PCR (PCR-like) using a pair of primers of nucleotide sequences according to the invention. The term “PCR-like” is intended to denote all the methods using direct or indirect reproductions of nucleic acid sequences, or else in which the labeling systems have been amplified; these techniques are, of course, known. In general, this involves amplification of the DNA with a polymerase; when the sample of origin is an RNA, a reverse transcription should be carried out beforehand. A very large number of methods currently exist for this amplification, such as, for example, the SDA (Strand Displacement Amplification) technique (Walker et al., 1992, Nucleic Acids Res. 20:1691), the TAS (Transcription-based Amplification System) technique described by Kwoh et al. (1989, Proc. Natl. Acad. Sci. USA, 86, 1173), the 3SR (Self-Sustained Sequence Replication) technique described by Guatelli et al. (1990, Proc. Natl. Acad. Sci. USA, 87:1874), the NASBA (Nucleic Acid Sequence Based Amplification) technique described by Kievitis et al. (1991, J. Virol. Methods, 35, 273), the TMA (Transcription Mediated Amplification) technique, the LCR (Ligase Chain Reaction) technique described by Landegren et al. (1988, Science 241,1077), the RCR (Repair Chain Reaction) technique described by Segev (1992, C. Kessler, Springer Verlag, Berlin, New-York, 197-205), the CPR (Cycling Probe Reaction) technique described by Duck et al. (1990, Biotechniques, 9, 142), and the Q-beta-replicase amplification technique described by Miele et al. (1983, J. Mol. Biol., 171,281). Some of these techniques have since been improved.

When the target polynucleotide to be detected is an mRNA, an enzyme of the reverse transcriptase type is advantageously used, prior to carrying out an amplification reaction using the primers according to the invention or to carrying out a method of detection using the probes of the invention, in order to obtain a cDNA from the mRNA contained in the biological sample. The cDNA obtained will then be used as a target for the primers or the probes used in the method of amplification or of detection according to the invention.

The invention further provides a kit comprising a nucleic acid, or a fragment or derivative thereof, as described above. In embodiments the kit comprises two fragments of a single nucleic acid of the invention and the fragments comprise a primer pair suitable for use to amplify a third fragment of the nucleic acid using an amplification method, such as PCR. The nucleic acid(s) in the kit are present in a suitable storage medium, e.g., buffered solution, typically in a suitable container. In some embodiments the nucleic acids are in dried form, and may be provided lyophilized. In embodiments the kit comprises a hybridization support of the invention. The kit may further include a buffer; reagents for polymerase chain reaction (e.g., deoxynucleotide triphosphates (dATP, dTTP, dCTP, and dGTP), a thermostable DNA polymerase, a buffer suitable for polymerase chain reaction, a solution containing Mg2+ ions (e.g., MgCl₂), and other components well known to those skilled in the art for carrying out a polymerase chain reaction). The kit may further include instructions for use of the kit that may be provided in a variety of forms, e.g., as printed information, on a compact disc, or the like. The kit may further include reagents necessary for extraction of nucleic acids from a sample (e.g., biopsy sample, blood, and the like) from an individual or a food product. The kits are useful in diagnostic applications, as described in more detail below. The kits are useful, for example, to detect the presence of a listeria contamination, in particular a L. monocytogenes contamination, and more particularly a L. monocytogenes serovar 4b contamination. The kits are also useful to determine whether an isolate of listeria belongs to the species L. monocytogenes and, if so, to determine the lineage and sublineage of the listeria. A kit of the invention is typically provided in packaged form.

While the present invention has been described with reference to the specific embodiments thereof, it should be understood by those skilled in the art that various changes may be made and equivalents may be substituted without departing from the true spirit and scope of the invention. In addition, many modifications may be made to adapt a particular situation, material, composition of matter, process, process step or steps, to the objective, spirit and scope of the present invention. All such modifications are intended to be within the scope of the claims appended hereto.

The following examples illustrate certain aspects of the invention. The examples in no way limit the invention.

EXAMPLES

The following experimental techniques and reagents were used in Examples I-VIII.

Bacterial Strains: The Listeria strains used were selected from the culture collection of the National Reference Center for Listeria, Institut Pasteur/Paris and from the production environment of different food plants. The strains were selected to represent all sv of L. monocytogenes, as well as disease and non-disease related isolates. A total of 93 L. monocytogenes strains of 12 different sv isolated from humans (sporadic and epidemic cases), foods, animals, and the environment as well as 20 representative strains of the different species of the genus Listeria (eight L. innocua, six L. ivanovii, two L. weishimeri, two L. seeligeri, and two L. grayi strains) were studied (Table 2). This set included eight epidemic strains from five outbreaks, 15 isolates from sporadic cases, and 19 strains from food plants. Strains were routinely grown overnight at 37° C. without agitation in TPB broth (GIBCO).

Strain CLIP 80489 was deposited at the CNCM on Sep. 10, 2003, under Accession No.1-3083. The deposit receipt is attached hereto.

Sequencing, Assembly and Sequence Analysis: The complete nucleotide sequence of strain CLIP 80489 was determined as described by Glaser et. al. (2001). In a first phase 35 609 shot-gun sequences were assembled into 334 contigs by using the Phred-Phrap-Consed software package (Gordon D, Abajian C, Green P., 1998, Consed: a graphical tool for sequence finishing. Genome Res. Vol. 8, pp 195-202). These sequences were obtained by sequencing both ends of plasmid clones from a shot-gun library constructed in pdDNA2.1 (Invitrogen). Ordering of contigs was performed by using CAAT-box (Frangeul et al, Bioinformatics, in press) and by comparison with the genome sequence of L. monocytogenes strain EGDe and L. innocua strain CLIP-1 1262. Finishing (gap closure and re-sequencing of low quality regions was performed by PCR amplification and sequencing of PCR products (830 sequencing reaction were performed for this second phase). The final sequence is 2 904 719 pb long. For annotation of the sequence, we used the program CMT-box (Frangeul et al. Bioinformatics, in press).

Primer design, PCR amplification and array construction: Primers were designed modified version of Primer 3 (CAAT-Box; Frangeul et al., unpublished) to amplify a fragment of 300 to 600 bp specific for each gene (melting temperature of 55-65° C., Eurogentec). Amplification reactions were performed in a 100 μl reaction volume containing 10-20 ng chromosomal DNA. The concentration and size of each PCR product was verified on agarose gels. For array preparation nylon membranes (Qfilter, GENETIX) were soaked in TE solution (10 mM Tris-pH 7, 1 mM EDTA, pH7.6). Spot blots of PCR products and controls were printed using a Opix robot (GENETIX). Following spot deposition, membranes were fixed for 15 min in 0.5 M NaOH, 1.5 M NaCl, washed briefly in distilled water and stored wet at −20° C. until use.

Hybridization: Genomic DNA was extracted using Quiagen DNeasy kit and radiolabeled using a Random Priming DNA Labeling kit (ROCHE). Labeling was performed with 500 ng of genomic DNA and 50 μCi ³³P-labeled dCTP (Amersham). Labeled probes were purified using Sephadex G-50 (ROCHE) or Qiaquick minicolumns (Quiagen). High density arrays were wetted in 2×SSC and pre-hybridized for 1 h in 10 ml of 5×SSPE [1.8×SSPE is 1.8M NaCl, 13 mM NaH₂PO₄, 87 mM Na₂HPO₄ and 15 mM EDTA (pH 8)], SDS 4%, 1×Denhardt's [Denhardt's 50× is 1% Ficoll, 1% Polyvinylpyrrolidone and 1% BSA] and lmg of denatured SaImon sperm DNA. Hybridization was performed overnight at 60° C. Membranes were washed twice at room temperature and twice at 60° C. in 0.5% SSPE, 0.2% SDS. Arrays were then sealed in polypropylene bags and exposed to a phosphor screen (Molecular Dynamics) for 24 h.

Verification of the specificity and quality of the macroarray: 15% of all PCR products were randomly chosen and sequenced. All 64 sequences corresponded to the expected PCR products. The membrane was then hybridized with chromosomal DNA isolated from the three Listeria strains used to amplify the probes (L. monocytogenes EGDe, L. innocua CLIP11262, L. monocytogenes CLIP80459) to test the quality and the correct spotting.

Data Analysis: For scanning a 445SI phosphorlmager (Molecular Dynamics) was used. The ArrayVision software (Imaging Research) was used for quantification of the hybridization intensities and for normalization. For each spot, the hybridization intensity value was normalized by dividing by the average of all significant intensity values on each filter. For ratio calculation a reference array was used, which was built by combing the average normalized data from three replicate hybridizations with the genomic DNA of L. monocytogenes EGDe, L. innocua CLIP11262 and L. monocytogenes CLIP80459 to the corresponding spots on the array. In order to define the cut off ratio for the presence of a gene the hybridization results for L. monocytogenes EGDe genes hybridized with L. innocua chromosomal DNA were analyzed. The threshold for the presence of a gene was defined as >0.3. This corresponds to a DNA similarity higher than >80% as verified by sequence comparisons of these genes in both genomes. The data were then converted into a binary score (at >0.3 a gene was scored as present =1, at <0.3 a gene was scored as absent =0). The binary data were analyzed by hierarchical clustering using the program J-Express [Dysvik, 2001 #2046], by neighbor joining using the program MVSP 3.1(Kovach Computing Services) and by intensive expert based data mining using Excel spread sheets.

Amplification reactions were performed in a 96-well plate in a final volume of 100 μl containing 2 U of Taq DNA polymerase (ROCHE, Boehringer), 0.2 mM of dNTPs (Perkin Elmer) and 0.5 mM of each of the primer sets. PCR was performed with an initial denaturation step at 94° C. for 3 min, 35 cycles of 94° C. for 0.40 min ; 53° C. for 1.15 min, 72° C. for 1.15 min and one final cycle of 72° C. for 7 min in a thermocycler (Icycler biorad). 5 μl of the reaction mixture was mixed to 3 μl of gel loading buffer and separated on a 1% agarose gel in 1× TBE. The PCR product was visualized by ethidium bromide staining.

Example I Construction of a Macroarray Comprising Genes from Epidemic L. monocytogenes, L. monocytogenes EGDe and L. innocua Strains

The 2906 kb long genome sequence of the epidemic L. monocytogenes sv 4b strain CLIP80459 (lineage II) was compared to the complete 2944 kb long genome sequence of L. monocytogenes EGDe (sv 1/2a, lineage I). 163 of the 2788 CLIP80459 genes (including 13 pseudogenes) were missing in EGDe. (The sequences of these genes have been assigned SEQ ID NOS: 1-163 and are presented in the attached Table 3. The amino acid sequences of the proteins encoded by the open reading frames (ORF) of these genes have been assigned SEQ ID NOS: 164-326 and are presented in the attached Table 4.) Thus, the genetic diversity between the two L. monocytogenes isolates is about 6%, quite close to that between L. monocytogenes EGDe and L. innocua (10.5%), which belong to two different species. The CLIP80459-specific genes include 14 surface proteins with an LPXTG motif, 14 ABC transport proteins, 2 PTS systems and 6 transcriptional regulators, suggesting that epidemic L. monocytogenes strains differ substantially in gene content from the L. monocytogenes EGDe strain (Table 5)

To extend the comparison from the three sequenced strains to a large collection of strains, high-density membranes were designed that were mainly focused on genes specific for each sequenced Listeria strain. This approach was chosen to increase the discriminatory power of the array. The membrane contained 409 probes, including 262 that were specific for L. monocytogenes EGDe relative to L. innocua CLIP11262 and all virulence genes, 94 that were specific for L. innocua CLIP11262 relative to L. monocytogenes EGDe, and 53 that were present only in L. monocytogenes CLIP80459, but absent from L. monocytogenes EGDe and L. innocua CLIP11262. The 53 genes that were present only in L. monocytogenes CLIP80459 are listed in Table 6, as are exemplary primer pairs that can be used to amplify fragments of the genes. All 409 genes contained on the membrane are listed in Table 7, together with exemplary primer pairs that can be used to amplify fragments of the genes. A description of the functional categories of the genes in listed in Table 8. This membrane was used to analyze 113 Listeria isolates.

The data obtained from the experiment are summarized in Table 17. Numbers indicate the percentage of the presence of the gene in the different groups or species of Listeria and the different L. monocytogenes sub-lineages. 8 strains of L. innocua, 6 strains of L. ivanovii, 2 strains of L. welshimeri, 2 strains of L. seeligeri, 2 strains of L. grayi and a total of 93 strains of L. monocytogenes, were evaluated in this study. L. monocytogenes strains were separated in this table into six sub-lineages. 27 strains (sv1/2a, 3a) 12 strains (sv 1/2c, 3c) 27 strains (sv 4b, 4d, 4e) 20 strains 3b, 7) 3 strains (sv 4a) and 2 strains (sv 4c) represented sub-lineage I.1, I.2, II.1, II.2, III.1, and III.2, respectively. The percentage of presence of each gene within the indicated groups is relative to the number of strains studied in each of these subdivisions.

Example II Strain Diversity and Overall Gene Distribution

Based on the macroarray hybridization data predicting the presence or absence of the studied genes, bifurcating trees illustrating possible phylogenetic relationships between the different Listeria were constructed, using the neighbor joining method. Important gene conservation within each species of the genus Listeria and within distinct groups of L. monocytogenes strains was identified. The analysis grouped all strains without exception according to their species. Thus, the Listeria array allows accurate species identification, although the probes were defined from only two Listeria species. Each species was defined by a combination of genes specifically present or absent.

For the species L. monocytogenes 30 marker genes were identified, 18 that were present in all 93 L. monocytogenes strains tested (Table 9, group I), and absent in all other isolates of the remaining Listeria species, and 12 that were present in all L. monocytogenes, except some or all of the five serovar 4a and 4c isolates tested (Table 9, group II). As serovar 4a and 4c strains are very rare and do not cause typical human listeriosis (12), these strains will not be considered in the analysis of species-specific marker genes but discussed separately. These 30 markers comprised the well-known virulence genes, (plcA, plcB, acta), seven surface protein-coding genes (inlA, inlB, inlH, inlE, Imo0333, Imo0835, Imo2821), one soluble internalin (Imo0549), three transcriptional regulators and eleven proteins of unknown function. For the species L. innocua we identified four markers (lin0739, lin0803, lin2741, lin2918) that were consistently present in all L. innocua strains tested. However, 29 of the 94 L. innocua genes spotted on the membrane were detected only in L. innocua, suggesting them to be species specific.

As the macroarray did not contain probes specific for the other Listeria species, no specific markers for these species could be defined. However, orthologs of about a third of the EGDe genes and about a quarter of the CLIP80459 or L. innocua genes were identified in at least one of the L. ivanovii, L. seeliger or L. whelshimeri strains. L. grayi was found to be the most distantly related species. From the 409 probes, only 12 (six from EGDe, three from L. innocua and three from CLIP80459) hybridized with DNA from L. grayi. These probes correspond to genes present in all Listeria species, like Imo1136, coding for an LPXTG protein, and genes coding for proteins of unknown function.

Example III Sub-Grouping Within the Species L. monocytogenes

The neighbor-joining method and hierarchical clustering (J-Express) were applied to identify specific gene clusters. Analysis of the 93 L. monocytogenes strains defined three lineages (I, II, and III) and distinguished two subdivisions within each lineage (FIG. 1). For each lineage and subgroup, specific markers were identified.

Nineteen genes were associated specifically with lineage I (Table 10, group A). Twelve of these genes clustered in two regions coding for proteins putatively involved in sugar metabolism (Imo0734-Imo0739 and Imo1968-Imo1974). Furthermore, a two-component regulatory system (Imo1060, Imo1061), an ABC transporter complex (Imo1062, Imo1063) and a gene coding for a surface protein containing an LPXTG motif (Imo0171) were lineage I-specific. Surprisingly, the bvr locus (bvrABC) (14) was present only in isolates of lineage I and in the two 4c strains. Eight genes allowed the sub-division of lineage I. They were present in lineage I.2 (sv 1/2c and 3c) but generally absent from lineage I.1 (sv 1/2a and 3a) (Table 10, group B).

Five of the 53 sv 4b-specific genes were markers for lineage II (Table 10, group C). Two code for transcriptional regulators, and three for surface proteins containing an LPXTG anchor. As sv 4b strains are mainly responsible for human listeriosis, it is of particular interest to identify markers for sv 4b strains or for the subgroup 4b, 4d, and 4e (lineage II.1). One such specific marker was ORF0799, coding for an unknown protein. ORF2372 (putative teichoic acid protein precursor C) and ORF2110 (putative secreted protein) were present only in sv 4b and two or four of the six L. ivanovii strains, respectively. (These three genes are shown in Table 10, group D.) Furthermore, 35 of the 53 sv 4b genes spotted were conserved in all 4b strains, and are thus implicated in the determination of characteristic features of sv 4b strains.

For lineage III strains (sv 4a and 4c), no specific genes were identified, because the macroarray did not contain representative sequences of this lineage. However, lineage III was characterized by the absence of over 37% (96 genes) of the EGDe genes spotted on the membrane. Thirteen genes, clustered in eight different chromosomal regions, were specifically absent from lineage III strains. They code for surface proteins (Imo1666, Imo0835), the arginine metabolic pathway (Imo0036 -Imo0041) and proteins of unknown function Imo96, Imo832, Imo1441, Imo1451, Imo2671). Strains of sv 4a (lineage III.1) are distinguished from those of sv 4c (lineage III.2) by the lack of additional 20 genes, seven of which code for cell surface proteins (inlC, inlEHG, Imo0333, Imo0549, Imo2821). These genes were also absent from all L. innocua strains tested.

Based on the data described above and reported in Table 9, Table 10, and Table 17 it is possible to design additional hybridization supports for use in typing of comprising sets of genes for use in typing L. monocytogenes isolates. An example of such a support, and results obtained using the support, is provided in Table 16.

Example IV Distribution of Known Virulence Genes

The virulence gene cluster of L. monocytogenes comprises prfA, plcA, hly, mpl, actA, and plcB. As these genes are a prerequisite for virulence of L. monocytogenes, differences in virulence among different isolates could be due to the absence of one or more of these genes. However, the macroarray hybridization showed that all 93 L. monocytogenes isolates contained this virulence gene cluster. The above-mentioned genes have been reported to also be present in L. ivanovii and L. seeligeri. In the macroarray assay, hybridization signals were detected for the hly, mpl and prfA genes, whereas the plcA, actA and plcB genes were either absent or did not give a signal due to a high divergence of the corresponding gene orthologs. Indeed, the sequence similarity of plcA, plcB, and actA from different L. ivanovii and L. seeligeri strains, as compared to L. monocytogenes EGDe, does not exceed 60%.

Several other genes of L. monocytogenes have been implicated in adhesion and internalization. Among those, the best studied are inlA and inlB. These two genes were detected in all L. monocytogenes strains tested, confirming their species-specificity. The uhpT gene (15) and the bsh gene (16) were identified in all isolates of the three hemolytic Listeria species (L. monocytogenes, L. ivanovii and L. seeligen).

Example V High Diversity of Surface Proteins Within the Species L. monocytogenes

Fifty-five genes coding for putative surface proteins belonging to the three sequenced Listeria genomes were spotted on the array. Among these, two groups of genes were identified. The first one comprises 25 genes specific for the species L. monocytogenes, including inlAB, the inlGHE cluster, inlF, and a number of surface proteins of unknown function (Table 11). Two (Imo0171, Imo2026) are lineage I specific and three (ORF2568, ORF1761, ORF0029) are lineage II specific. lnlG seems to be specifically absent from all lineage II and sv 4a strains. None of the sv 4b surface protein-coding genes was identified in L. monocytogenes 1/2c and 3a strains. For L. innocua, two specific surface protein-coding genes (lin0739, lin0803) were identified. The second group comprises surface protein-coding genes heterogeneously distributed among the different Listeria isolates and species (Table L. monocytogenes 3).

To corroborate the hybridization results, six of the surface proteins specific for L. monocytogenes (inlA, inlB, inlE, inlG, inlH, inlF) and two of the surface proteins found within several or all Listeria species (Imo0550, Imo1289), were amplified by PCR in one reference strain for each sv and for each species. The PCR amplifications confirmed the array results.

Example VI Carbohydrate Metabolism and Phosphotransferase Systems (PTS)

The distribution of genes for twelve PTS permeases and 14 genes coding proteins predicted to be implicated in sugar metabolism and degradation was similar to that of surface protein coding genes; all genes were highly conserved in lineage I strains and most were lacking in the other Listeria species. Except for two PTS genes (Imo2733, Imo2782) and three carbohydrate metabolism genes (Imo2143, Imo2735, Imo2781), all other genes were missing in the L. monocytogenes sv 4a strains.

Example VlI Cell Wall Proteins—Two sub-divisions within Teichoic Acid Biosynthesis Genes

Despite the fact that the majority of genes grouped the 93 L. monocytogenes strains according to previously defined lineages, which correlate mainly with the flagellar antigen combinations (serovars), 13 genes implicated in cell wall biosynthesis where identified that divide the L. monocytogenes strains into two groups according to their somatic antigen (serogroups 4 and serogroup 1/2, 3, 7). These genes code for teichoic acid biosynthesis proteins and were detected only within the strains of serogroup 1/2, 3 and sv 7, but were absent from strains of serogroup 4. This finding is in agreement with previous studies that have identified two distinct structural types of teichoic acid within L. monocytogenes, where the first type was found in strains of serogroup 1/2, 3 and 7 and the second in strains of serogroup 4 (17). This suggests that these genes may be implicated in the synthesis of this specific teichoic acid type. Nine of these genes located within a 19 kb region of the L. monocytogenes chromosome (Imo1076-Imo1077, Imo1080-Imo1084, Imo1088, Imo1091), were also shared with the L. seeligeri strains, which are of serogroup 1/2, suggesting that L. seeligeri has a teichoic acid type similar to that of L. monocytogenes serogroup1/2.

Similarly, one (lin1073) of two L. innocua genes implicated in teichoic acid biosynthesis was uniquely shared with the L. monocytogenes strains of serogroup 4 and with L. weslhimeri. This is consistent with the suggestion that the cell wall type of the serogroup 4 strains of L. monocytogenes is more closely related to that of serogroup 6 of L. innocua than to that of L. monocytogenes 1/2 strains (17).

Example VIII Variable Genomic Regions and Analysis of Junction Sequences

Several L. monocytogenes EGDe gene clusters were missing only from L. monocytogenes sv 4a strains but were present in all other L. monocytogenes strains. Two regions were absent from L. monocytogenes sv 4a and L. innocua, but were present in L. ivanovii, L. seeligeri and L. welshimeri. These regions seemed good candidates as evolutionary markers. To further analyze them, the junction regions of the putative deletion sites in six isolates of L. innocua and L. monocytogenes sv 4a were sequenced.

Analysis of region Imo2671- Imo2672 revealed the existence of three deletion events, two of which were located in the coding sequence of Imo2672, resulting in the deletion of two internal fragments of 621 bp and 35 bp. The third deletion was 355 bp long and located downstream of the 5′ end of the coding sequence of Imo2671. All three junction sequences were identical, containing either an insertion of TTGCATT, A or no insertion (FIG. 5A). An analysis of the junction sequence of region Imo2771-Imo2773 yielded the same result, with identical junction sites in the six strains sequenced 38 bp downstream of the 3′ end of Imo2770. The junction site had an insertion of the sequence TTATTTAAG replacing the genes Imo2771 to Imo2773 (FIG. 5B).

The third region investigated (Imo1030-Imo1036) was absent from L. innocua and L. monocytogenes 4a strains and present in L. ivanovii. The analysis of the junction region identified a minor sequence variation (insertion of TCA in L. innocua and of AT in L. monocytogenes sv 4a) at the deletion site (FIG. 5C).

Finally, the inlGHE cluster, which is missing in L. monocytogenes 4a and all other Listeria sp. was analyzed. Again, an identical sequence in the five strains sequenced was observed, suggesting that a single deletion event had occurred in a common ancestor of L. monocytogenes sv 4a and L. innocua (FIG. 5D).

Example IX Multiplex PCR

The experiments described in the preceding examples identified nineteen genes from L. monocytogenes EGDe strain (Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 and Imo1974) and five genes for the L. monocytogenes CLIP80459 strain (ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF 1761) as a marker genes, based on their specific detection in L. monocytogenes strains of serovars 1/2a-1/2c and 1/2b-4b, respectively. Moreover, strains of serovars 1/2c and 4b were specifically distinguished by the presence of eight additional genes of L. monocytogenes EGDe (Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 and Imo1119) and three genes of L. monocytogenes CLIP80459 (ORF 799, ORF 2372 and ORF 2110), respectively.

These marker genes can be used in a PCR assay that classifies L. monocytogenes into four distinct groups in correlation with the four major serovars (1/2a, 1/2b, 1/2c and 4b). Four L. monocytogenes serogroup marker genes were selected to develop the multiplex PCR assays. The tests were carried out in 96 well microplate format, allowing large scale application. A total of 160 strains of L. monocytogenes and 20 strains representing species L. innocua (10 strains of serovar 6a and 6b), L. ivanovii (8 strains of serovar 5), L. welshimeri (2 strains of serovar 6a and 4c) and L. seeligeri (2 strains of serovar 1/2b), were evaluated in this study (Table 1). Among L. monocytogenes strains, serovars 1/2a, 1/2b, 1/2c and 4b were each represented by 40 strains, half of which were isolated from foods and half from human sporadic cases of listeriosis and which were isolated over the period from 2000 to 2002 and collected by the National Reference Centre (NRC) at Institut Pasteur. Serovar reference strains were also used in this study. Strain identification and conventional serotyping were done according to standard methods (Bille et al. 1992; Seeliger and Höhne. 1979).

For PCR, three to five bacterial colonies were emulsified in 50 μl of a 0.25% sodium dodecyl sulfate-0.05 N NaOH solution and incubated at 99° C. for 15 min. Then, 100 μl of H₂O was added to the mixture and 2 μl of the diluted mixture was used in PCR. Multiplex PCR assays were performed by combining six primer sets in a single reaction. Two of these primer sets were designed to target marker gene Imo0737 of L. monocytogenes EGDe strain and ORF 2819 of L. monocytogenes CLIP 80459 strain, specific to L. monocytogenes serovars 1/2a-1/2c and 1/2b-4b respectively. To further distinguish L. monocytogenes serovar 1/2c from 1/2a and serovar 4b from 1/2b, two primer sets targeting the serovar 1/2c marker gene Lmo1119 of L. monocytogenes EGDe and the serovar 4b marker gene ORF2110 of L. monocytogenes CLIP 80459 strain, were included. Finally, prs gene was also targeted by a primer pair for an internal PCR amplification control, as it was highly conserved among all listeria species. Primer sequences and predicted lengths of amplified fragments are outlined in Table 12.

As a demonstration of the PCR approach, the four major serovars 1/2a, 1/2b, 1/2c and 4b of the pathogeneic L. monocytogenes species were separated based on the amplification of four of the serogroup marker genes already described.

The first set of primers was designed to amplify 691 bp fragment of gene Imo0737, a transcription regulator of the Lacl family of the L. monocytogenes EGDe strain, selected from the nineteen marker genes identified as specific for L. monocytogenes strains of serovars 1/2a, 1/2c, 3a and 3c. From the eight marker genes specific for L. monocytogenes strains of serovars 1/2c and 3c, primers were designed to amplify a 782 bp fragment of the DNA methyl transferase encoded by gene Imo1119 of L. monocytogenes EGDe. PCR primers for this assay were also designed to amplify a 471 bp fragment of the ORF 2819 of L. monocytogenes CLIP80459, a cell surface protein containing a LPXTG anchor motif identified with four other genes as specific markers for L. monocytogenes strains of serovars 1/2b, 3b, 7, 4b, 4d and 4e. The three marker genes characterizing L. monocytogenes strains of serovars 4b, 4d and 4e were tested in this study by the amplification of 600 bp fragment covering ORF 2110 of L. monocytogenes CLIP80459 strain, encoding a putative secreted protein.

Thus, amplification of gene Imo1119 (782 pb band) and gene Imo0737 (691 pb band) indicates a 1/2c or 3c serovar, while the single amplification of gene Imo0737 (691 bp band) would indicate a 1/2a or 3a serovar (FIG. 4). In contrast, the amplification of ORF2819 (471 pb band) and ORF2110 (600 bp band) is associated with serovars 4b, 4d or 4e. The unique amplification of the ORF 2819 (471 bp band) indicates a serovars of 1/2b, 3b or 7 (FIG. 4). The suitability of the PCR method to detect serovars was first evaluated with the serovar reference strains of the L. monocytogenes species. As shown in (FIG. 4), the size of the amplicons obtained from the multiplex PCR was identical to those predicted from the design of the primers, and amplification profiles, as expected, separate serovars 1/2a-3a, 1/2c-3c, 1/2b-3b-7 and 4b-4d-4e. Thus, this PCR assay allows identification of species of L. monocytogenes as belonging to one of four distinct groups. Multiplex PCR profiles combine serovars 1/2a with 3a, 1/2c with 3c, 1/2b with 3b-7 and 4b with 4d-4e. However, the probability of such confusions will still be limited since the remaining six currently recognized L. monocytogenes serovars are infrequent in food and rarely reported to be implicated in human listeriosis (Tappero et al. 1995; Graves et al. 1999).

Example X Specificity and Evaluation of a Representative Multiplex PCR Assay

To evaluate the specificity and the reproducibility of the multiplex PCR method, 160 strains of L. monocytogenes species, and 20 strains representing other listeria species were tested: L. innocua (10 strains), L. ivanovii (8 strains), L. welshimeri (2 strains) and L. seeliger (2 strains). The serovar classifications obtained from interpretation of the PCR results were then compared with those obtained using conventional serotyping methods. In all strains from the species L. innocua, L. ivanovii, L. seeligeri and L. welshimeri, the only amplified gene was the prs control (348 bp band) (FIG. 4). Results summarized in Table 13 show that the serovar classifications determined from the PCR results were in complete concordance with the classifications obtained using the conventional serotyping methods for all strains of the species L. monocytogenes assayed, confirming the reproducibility and accuracy of the PCR method.

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TABLE 1 Strains used in the multiplex PCR assay Strain Species Origin Serovar CLIP80722 L. monocytogenes Human 1/2a CLIP80730 L. monocytogenes Human 1/2a CLIP80841 L. monocytogenes Human 1/2a CLIP80853 L. monocytogenes Human 1/2a CLIP80888 L. monocytogenes Human 1/2a CLIP81049 L. monocytogenes Human 1/2a CLIP81209 L. monocytogenes Human 1/2a CLIP82243 L. monocytogenes Human 1/2a CLIP82823 L. monocytogenes Human 1/2a CLIP83088 L. monocytogenes Human 1/2a CLIP83240 L. monocytogenes Human 1/2a CLIP83283 L. monocytogenes Human 1/2a CLIP83434 L. monocytogenes Human 1/2a CLIP83641 L. monocytogenes Human 1/2a CLIP83792 L. monocytogenes Human 1/2a CLIP84054 L. monocytogenes Human 1/2a CLIP84084 L. monocytogenes Human 1/2a CLIP84191 L. monocytogenes Human 1/2a CLIP84244 L. monocytogenes Human 1/2a CLIP84248 L. monocytogenes Human 1/2a CLIP91992 L. monocytogenes Food 1/2a CLIP92009 L. monocytogenes Food 1/2a CLIP92062 L. monocytogenes Food 1/2a CLIP92121 L. monocytogenes Food 1/2a CLIP92130 L. monocytogenes Food 1/2a CLIP92204 L. monocytogenes Food 1/2a CLIP92216 L. monocytogenes Food 1/2a CLIP92227 L. monocytogenes Food 1/2a CLIP92294 L. monocytogenes Food 1/2a CLIP92306 L. monocytogenes Food 1/2a CLIP92312 L. monocytogenes Food 1/2a CLIP92325 L. monocytogenes Food 1/2a CLIP92331 L. monocytogenes Food 1/2a CLIP92344 L. monocytogenes Food 1/2a CLIP92360 L. monocytogenes Food 1/2a CLIP92439 L. monocytogenes Food 1/2a CLIP92443 L. monocytogenes Food 1/2a CLIP92450 L. monocytogenes Food 1/2a CLIP92456 L. monocytogenes Food 1/2a CLIP92461 L. monocytogenes Food 1/2a CLIP80663 L. monocytogenes Human 1/2b CLIP80723 L. monocytogenes Human 1/2b CLIP80731 L. monocytogenes Human 1/2b CLIP80914 L. monocytogenes Human 1/2b CLIP80970 L. monocytogenes Human 1/2b CLIP83180 L. monocytogenes Human 1/2b CLIP83293 L. monocytogenes Human 1/2b CLIP83482 L. monocytogenes Human 1/2b CLIP83775 L. monocytogenes Human 1/2b CLIP84085 L. monocytogenes Human 1/2b CLIP84294 L. monocytogenes Human 1/2b CLIP84320 L. monocytogenes Human 1/2b CLIP84515 L. monocytogenes Human 1/2b CLIP84522 L. monocytogenes Human 1/2b CLIP84688 L. monocytogenes Human 1/2b CLIP84809 L. monocytogenes Human 1/2b CLIP84899 L. monocytogenes Human 1/2b CLIP84974 L. monocytogenes Human 1/2b CLIP84981 L. monocytogenes Human 1/2b CLIP85102 L. monocytogenes Human 1/2b CLIP90640 L. monocytogenes Food 1/2b CLIP90861 L. monocytogenes Food 1/2b CLIP90979 L. monocytogenes Food 1/2b CLIP91313 L. monocytogenes Food 1/2b CLIP91357 L. monocytogenes Food 1/2b CLIP91428 L. monocytogenes Food 1/2b CLIP91580 L. monocytogenes Food 1/2b CLIP91592 L. monocytogenes Food 1/2b CLIP91865 L. monocytogenes Food 1/2b CLIP91959 L. monocytogenes Food 1/2b CLIP92008 L. monocytogenes Food 1/2b CLIP92052 L. monocytogenes Food 1/2b CLIP92182 L. monocytogenes Food 1/2b CLIP92192 L. monocytogenes Food 1/2b CLIP92198 L. monocytogenes Food 1/2b CLIP92205 L. monocytogenes Food 1/2b CLIP92390 L. monocytogenes Food 1/2b CLIP92429 L. monocytogenes Food 1/2b CLIP92441 L. monocytogenes Food 1/2b CLIP92445 L. monocytogenes Food 1/2b CLIP80665 L. monocytogenes Human 1/2c CLIP80669 L. monocytogenes Human 1/2c CLIP80724 L. monocytogenes Human 1/2c CLIP84516 L. monocytogenes Human 1/2c CLIP85078 L. monocytogenes Human 1/2c CLIP85305 L. monocytogenes Human 1/2c CLIP86391 L. monocytogenes Human 1/2c CLIP86600 L. monocytogenes Human 1/2c CLIP87640 L. monocytogenes Human 1/2c CLIP87923 L. monocytogenes Human 1/2c CLIP87968 L. monocytogenes Human 1/2c CLIP89425 L. monocytogenes Human 1/2c CLIP89496 L. monocytogenes Human 1/2c CLIP89796 L. monocytogenes Human 1/2c CLIP90481 L. monocytogenes Human 1/2c CLIP90606 L. monocytogenes Human 1/2c CLIP91334 L. monocytogenes Human 1/2c CLIP91363 L. monocytogenes Human 1/2c CLIP91383 L. monocytogenes Food 1/2c CLIP91450 L. monocytogenes Food 1/2c CLIP91588 L. monocytogenes Food 1/2c CLIP91767 L. monocytogenes Human 1/2c CLIP91855 L. monocytogenes Food 1/2c CLIP91875 L. monocytogenes Food 1/2c CLIP91929 L. monocytogenes Food 1/2c CLIP91945 L. monocytogenes Food 1/2c CLIP91980 L. monocytogenes Food 1/2c CLIP91983 L. monocytogenes Food 1/2c CLIP92007 L. monocytogenes Food 1/2c CLIP92077 L. monocytogenes Human 1/2c CLIP92080 L. monocytogenes Food 1/2c CLIP92124 L. monocytogenes Food 1/2c CLIP92221 L. monocytogenes Food 1/2c CLIP92322 L. monocytogenes Food 1/2c CLIP92353 L. monocytogenes Food 1/2c CLIP92359 L. monocytogenes Food 1/2c CLIP92363 L. monocytogenes Food 1/2c CLIP92447 L. monocytogenes Food 1/2c CLIP92468 L. monocytogenes Food 1/2c CLIP92470 L. monocytogenes Food 1/2c CLIP80650 L. monocytogenes Human 4b CLIP80671 L. monocytogenes Human 4b CLIP80701 L. monocytogenes Human 4b CLIP80721 L. monocytogenes Human 4b CLIP80751 L. monocytogenes Human 4b CLIP80759 L. monocytogenes Human 4b CLIP80760 L. monocytogenes Human 4b CLIP80776 L. monocytogenes Human 4b CLIP80849 L. monocytogenes Human 4b CLIP80879 L. monocytogenes Human 4b CLIP80882 L. monocytogenes Human 4b CLIP80963 L. monocytogenes Human 4b CLIP81101 L. monocytogenes Human 4b CLIP81117 L. monocytogenes Human 4b CLIP81146 L. monocytogenes Human 4b CLIP81252 L. monocytogenes Human 4b CLIP81438 L. monocytogenes Human 4b CLIP81594 L. monocytogenes Human 4b CLIP82016 L. monocytogenes Human 4b CLIP82169 L. monocytogenes Human 4b CLIP91390 L. monocytogenes Food 4b CLIP91555 L. monocytogenes Food 4b CLIP91590 L. monocytogenes Food 4b CLIP91686 L. monocytogenes Food 4b CLIP91740 L. monocytogenes Food 4b CLIP91781 L. monocytogenes Food 4b CLIP91806 L. monocytogenes Food 4b CLIP91863 L. monocytogenes Food 4b CLIP91899 L. monocytogenes Food 4b CLIP91909 L. monocytogenes Food 4b CLIP91921 L. monocytogenes Food 4b CLIP91942 L. monocytogenes Food 4b CLIP91950 L. monocytogenes Food 4b CLIP92085 L. monocytogenes Food 4b CLIP92209 L. monocytogenes Food 4b CLIP92278 L. monocytogenes Food 4b CLIP92288 L. monocytogenes Food 4b CLIP92334 L. monocytogenes Food 4b CLIP92406 L. monocytogenes Food 4b CLIP92449 L. monocytogenes Food 4b CLIP91375 L. innocua Food ND CLIP91443 L. innocua Food 6b CLIP91549 L. innocua Food 6b CLIP91879 L. innocua Food 6b CLIP91918 L. innocua Food 6a CLIP91922 L. innocua Food 6b CLIP92006 L. innocua Food 6b CLIP92186 L. innocua Food 6b CLIP92218 L. innocua Food 6b CLIP92310 L. innocua — — CLIP 74914 L. ivanovii/ivanovii — 5 CLIP 88111 L. ivanovii/ivanovii Food 5 CLIP 86784 L. ivanovii/ivanovii Food 5 PAM55 L. ivanovii/ivanovii — 5 CLIP 6645 L. ivanovii/Iondoniensis — 5 CLIP 12065 L. ivanovii/Iondoniensis — 5 CLIP 73021 L. seeligeri — 1/2b CLIP 86579 L. seeligeri — 1/2b CLIP 87073 L. welshimeri — 4c CLIP 87973 L. welshimeri — 6a CLIP: Strain number in the Listeria Culture collection of the National Reference Center for Listeria, Institut Pasteur ND: Non-determined serovar

TABLE 2 Strains Used in DNA/DNA Macroarray Hybridization Analysis Strain Species Origin Serovar Year Country CLIP 61673 L. monocytogenes Human, 7 1995 France sporadic CLIP 74917 L. monocytogenes * 7 — — CLIP 42636/T23 L. monocytogenes Human, 1/2a — UK epidemic CLIP 46664/T20 L. monocytogenes Food 1/2a — USA CLIP 46682/T56 L. monocytogenes Human, 1/2a — USA sporadic CLIP42663/T77 L. monocytogenes Human, 1/2a — USA sporadic CLIP 46661/T14 L. monocytogenes Human, 1/2a — USA sporadic CLIP 42651/T53 L. monocytogenes Animal, 1/2a — UK sporadic CLIP 9429 L. monocytogenes Human, 1/2a 1988 France sporadic CLIP 74902/ L. monocytogenes * 1/2a — — ATCC35152 CLIP 61523 L. monocytogenes Food 1/2a 1994 France CLIP 61678 L. monocytogenes Food 1/2a — France CLIP 61634 L. monocytogenes Human, 1/2a 1995 France sporadic CLIP 61839 L. monocytogenes Food 1/2a — France CLIP 61868 L. monocytogenes Human, 1/2a 1995 France sporadic CLIP 87880 L. monocytogenes Food 1/2a 1992 France CLIP 87881 L. monocytogenes Food 1/2a 1993 France Environmental CLIP 87884 L. monocytogenes Food 1/2a 1992 France Environmental CLIP 87890 L. monocytogenes Food 1/2a 1992 France CLIP 69566 L. monocytogenes Environmental 1/2a — France CLIP 80559 L. monocytogenes Environmental 1/2a — — CLIP 60368 L. monocytogenes Environmental 1/2a 1994 France CLIP 14843 L. monocytogenes Environmental 1/2a — France CLIP 89461 L. monocytogenes Environmental 1/2a — Danemark CLIP 89458 L. monocytogenes Food 1/2a — Danemark CLIP 87908 L. monocytogenes — 1/2a — — CLIP EGD L. monocytogenes — 1/2a — — CLIP 46686/T64 L. monocytogenes Human, 1/2b — USA sporadic CLIP 42655/T61 L. monocytogenes Food 1/2b — USA CLIP 989 L. monocytogenes Human, 1/2b 1981 USA sporadic CLIP 3559 L. monocytogenes Human, 1/2b — Argentina sporadic CLIP 87878 L. monocytogenes Food 1/2b 1993 France Environmental CLIP 87879 L. monocytogenes Food 1/2b 1992 France CLIP 87888 L. monocytogenes Food 1/2b 1992 France CLIP 87897 L. monocytogenes Food 1/2b 1999 France Environmental CLIP 87909 L. monocytogenes Food 1/2b 1999 France CLIP 87910 L. monocytogenes Food 1/2b 1993 France Environmental CLIP 70086 L. monocytogenes Environmental 1/2b 1995 Argentina CLIP 70848 L. monocytogenes Environmental 1/2b 1996 Espagne CLIP 76278 L. monocytogenes Environmental 1/2b 1998 France CLIP 14842 L. monocytogenes Environmental 1/2b — France CLIP 89460 L. monocytogenes Environmental 1/2b — Danemark CLIP 46694/T80 L. monocytogenes Human, 1/2c — UK sporadic CLIP 42653/T57 L. monocytogenes Human, 1/2c — UK sporadic CLIP 42972/T8 L. monocytogenes Human, 1/2c — UK sporadic CLIP 2710 L. monocytogenes Human, 1/2c — Czech sporadic Republic CLIP 11550 L. monocytogenes Food 1/2c — France CLIP 87891 L. monocytogenes Food 1/2c — — Environmental CLIP 87892 L. monocytogenes Food 1/2c — — Environmental CLIP 87893 L. monocytogenes Food 1/2c — — Environmental CLIP LO028 L. monocytogenes — 1/2c — — CLIP 86436 L. monocytogenes Food 3a 2000 France CLIP 74905/ L. monocytogenes * 3a — — ATCC19113 CLIP 8053 L. monocytogenes Environmental 3a 1987 Finland CLIP 74906 L. monocytogenes * 3b — — CLIP 87900 L. monocytogenes Food 3b — Environmental CLIP 3558 L. monocytogenes Animal 3b — Argentina CLIP 11962 L. monocytogenes Food 3c — France CLIP 85412 L. monocytogenes Food 3c 2000 France CLIP 74907 L. monocytogenes * 3c — — CLIP 74908/ L. monocytogenes * 4a — — ATCC19114 CLIP 78025 L. monocytogenes — 4a — Germany CLIP 71988 L. monocytogenes — 4a — — CLIP 73722 L. monocytogenes Human, 4b 1997 France sporadic CLIP 46684/T60 L. monocytogenes Environmental 4b — Switzerland CLIP 46679/T50 L. monocytogenes Food, epidemic 4b — Canada CLIP 42635/T21 L. monocytogenes Human, 4b — Switzerland epidemic CLIP 42652/T55 L. monocytogenes Food, epidemic 4b — Switzerland CLIP 42639/T29 L. monocytogenes Human, 4b — USA epidemic CLIP 42646/T43 L. monocytogenes Food, epidemic 4b — USA CLIP 4598 L. monocytogenes Food 4b — Switzerland CLIP 2698 L. monocytogenes Human 4b — Czech Republic CLIP 8715 L. monocytogenes Human 4b 1988 Suisse CLIP 74910/ATCC L. monocytogenes * 4b — — 19115 CLIP 22573 L. monocytogenes Human, 4b 1992 France epidemic CLIP 27993 L. monocytogenes Food 4b 1992 France CLIP 87889 L. monocytogenes Food 4b — — Environmental CLIP 87896 L. monocytogenes Food 4b — — Environmental CLIP 87911 L. monocytogenes Food 4b — — CLIP 87915 L. monocytogenes Food 4b — — CLIP 87917 L. monocytogenes Food 4b — — CLIP 72783 L. monocytogenes Environmental 4b 1996 Switzerland CLIP 60383 L. monocytogenes Environmental 4b 1994 France CLIP 87691 L. monocytogenes Environmental 4b — Portugal CLIP 80459 L. monocytogenes Human, 4b 1999 France epidemic CLIP 74911/ L. monocytogenes * 4c — — ATCC19116 CLIP 86309 L. monocytogenes Food 4c — France CLIP 81065 L. monocytogenes Animal 4c 2000 Switzerland CLIP 74912/ L. monocytogenes * 4d — — ATCC19117 CLIP 79619 L. monocytogenes Animal 4d 1999 Switzerland CLIP 74913/ L. monocytogenes * 4e — — ATCC19118 CLIP 78003 L. monocytogenes — 4e — Germany CLIP 79455 L. monocytogenes — 4e — — CLIP 71990 L. innocua — 6b — — CLIP 71989 L. innocua — 6b — — CLIP 74915/ L. innocua * 6a — — ATCC33090 CLIP 74916/ L. innocua * 6b — — ATCC33091 CLIP 88566 L. innocua Food 6a — France CLIP 88307 L. innocua Food 6b 2001 France CLIP 86490 L. innocua Food ND — Maroc CLIP 11262 L. innocua Food 6a 1988 Maroc CLIP 74914/ L. ivanovii/ivanovii * 5 — — ATCC19119 CLIP 88111 L. ivanovii/ivanovii Food 5 2001 France CLIP 86784 L. ivanovii/ivanovii Food 5 — France PAM55 L. ivanovii/ivanovii — 5 — — CLIP 6645 L. — 5 — Switzerland ivanovii/londoniensis CLIP 12065 L. Animal 5 — Belgium ivanovii/londoniensis CLIP 73021/ L. seeligeri * 1/2b — — ATCC35967 CLIP 86579 L. seeligeri — 1/2b — — CLIP 87073 L. welshimeri Environmental 4c — France CLIP 87973 L. welshimeri — 6a — France CLIP 73019 L. grayi — — — — CLIP 12515 L. grayi spp. — — — — murrayi CLIP: Strain number in the Listeria Culture collection of the National Reference Center for Listeria, Institut Pasteur. ATCC/Strain number in the American type Culture Collection, * Indicates reference strains for serotyping. T: Numbers according to the strain set of the international WHO multicenter typing study.

TABLE 3 ORF1025 (SEQ ID NO:1) GGATACGGGAGTGTGGCGCTCGTCATGAAGATAAACAAAATTATCGAATA TATTGTAGTAGCAATCATCGTTTTAGGTTGGACTTACTTCATTGTTATTA AAGAAATTCTCCCTAAAAATATAGGATTTATTTCATTAGTAATTTTATCA ATAATTCTTTATTTTGTAGGCAAAAGGTTGAATGGGAAACATAGCAGATA A ORF104 (SEQ ID NO:2) GAGAAAAGTATGAAAAAAATACTTGGCGGAATCTTAATTATTTTTGTAAT AGGCCTGTTTGCTTGGCGCGTATATGATGTAAAAGCTAATTCTTTTTCAT ATGAAAATAAGGCACATGCTGAACAGGAAAAATTTCAACTTGGAAGCTCA ACAATCAGTGCTGGAAAAGCATTTGTTGTAAGTGATGCAGACTTAAATAA ATATGTGACAAAAGATTATTTTAAGCAGGAAAATAAGACTCTTTTGCTCG TTCAATTAGAATCTACAGAAAAAGATATAAGAATTTCTGATTTTCAGTTA GGGTATAAAGAATTTGTAACGTTGTCAGATACTTCGGCAGCAAGTTATGA ATTTGAAGATGGGGTGTATAAAATGGTGTTAGGTTTTAATATACCTAAAG AATTACTAGCAACTAACAAGACATTCACATTAGTTACTCCGAGTAAATAT TGGAAGAACGGAGCAAGGGATGTTGTGGAAATCAGTTTATAA ORF105 (SEQ ID NO:3) ACTAAACTAGGGAGAATATCGATGAATTATATAAAAGTTAATCATTTAAC AAAAGTAATCAACAACAACACTGTACTAGATGATATTAATTTTGAATTAA AGCAAGGTGGGATTTATTCGTTCATAGGTCATAATGGCTCTGGAAAAACG ATGCTTTTTAGGGCGTTATGCGGTTTTATTGCGCCAACAAGTGGTGAAGT TACAATTAATGGCATTAGTATTAGCAAAACTAGATCTTTCCCAGAAAAGA CCGGAATTATTATTGAAACGCCAGGCTTTTTAGCAAATTATACTGGTTAT AAAAATTTGGAATACTTAGCTTCTATTAGAAATCAAATAGGTGAAAAGGA AATACTTGCTGCGTTAGAACAAGTTGGACTTTCTGGAAAAGAGAACTTGA AAGTGAAAAAATATTCGCTTGGAATGAGACAACGGCTTGGTATTGCTCAA GCTATTATGGAAGACCCAGATTTATTAATATTTGACGAACCAACAAATTC GTTAGATAAAGCTGGCAGTCAGAGTTTTATTGACTTGATTTTAGACTTAA AAGAAAAAGGAAAAACGATTTTGTTAGCAAGCCATCATATTGCTGATATT GATGGTATATCAGATGAAATATTTGAAATGGAAGCAGGTCAGATAATAAA TAGGAGAAAAGTATGA ORF1063 (SEQ ID NO:4) ATTGGAGGAGATAGGATGAAAAATCTATTTAGACTATTCTTGGTATTTAG CATAGTTATTATCGGGGTTGTTTCTTTTCAAGCGATAGATGCAAGTGCAA ATGAGACAGATGTATATCCATTACCAGCCAGAATAATTGATGTTTTCCCA GATGAAAATTTAGCAGAAGATATGGTGGAGAACTTTGGTAAAAAAGATGT GACAGATGTAATTACCCAAGATGATGTGGATGCGGTGACATCTCTAGGGT TGGGTTATTTTACCAATTACCTCACAGATGAAGATTTACAAATGCTAGGA AATGCTTATTTTACCAATGTAAATAATATTATGATTTATCCTACACAAAC CATGTTTACTGGCTTTCCTGATTTACCAACCTTGCCCAAATTAGATACTT TGAGAGCAGAAGGAAATCTATCAAGCGAGGTACTACCTGAAAACATTACA GTTCCCGATTATCAAAACTACCCAGAATTAAAGTATCTTGATCTTAGTAA TCGAACTATTGTTGGGGGCTTACCTAACTTTTCTAATATTCCTAAATTAG AAACCTTGTTGATGAGCAGTTGTGGACTAGCTTCGGAAGACGCTCCAGAT TTTACAAACTTGAAAAATTTGCAGAAAGTAAATTTTCAAACGAACCAATT TAGAACAGAAATGACGGATTTCACTCATTTGGACAGTTTGGTAAGTATGG ATTTAAGTTATAATTATTTAAATGTGTTGCCGCCTACTATTGTGGATAAA GTAATCGTACTAGGTCAAATCGGAACTTTGCCAGATCAAAATGTTGTTTT TGGTGAGGATACAAATATCACGCTACCAGTTTATACGCAACTAGATGATT TAGGTAGAATTAGTGGTTTTCAAGAAGTTTGGATTCGTGATTCAAATGAG AAGGAAATTTACAACGTGGCAAAAGTGGATTACGACGAAGTGACGAAGCA GATTATTGTGCCAACAAATAACCTTGATAAAGGTGAATACACTATTGGAA TTGATTTTAATGGAATAGAGCCTTATATAGAAGAAGGCGAAGTTATGAAT TACTCAGTAAAAATAACCATTAATTAA ORF1227 (SEQ ID NO:5) AAAATAAAAGGATATATCAATGTGAATATAACTAAAAACGGATTATATAT AATTATTGGGGCAAATGGAGTAGGGAAAACAACATTAGCTAAGAAAATAC TTCAAGCTAACAGAAGTATTAGTTGCATGATGAAGCAAGATGATAATCAA ATATTGGAGTATGAGACGGTTTTAACCAATATTAGTATGAACGAAATCGC AGAAAAAACGGTTATTAATTTTCTGGAAGAACATCAATTAGACTATTTAA TAACTAAAAAAAGTAAATTTCTTAGTGGGGGAGAAAAAAGATTAGTTAAC CTTCTAAGAGCTATTTTGTCAAATCAAGAAGTATTGATATTAGATGAGCC ATCAAATGACTTAGATATTGATGTATTTGAGAAGGCAAAACAAATTATTT ATCAAGCGGCAAAATCTAAAATAATACTATTAATTACGCATGATGATCGT TTTACCGAATATGATAAAAAAATAGAAATAATGAAGAATCAAAGTTACGA AGCAGATAGTTTCAGCTTTAATAAAGAAAGTTCGAAAGCGCGCATTATCA AAATTAAACCTAGAAGGACCTATTTCTTATATATCTTCTATTTAATTTGT ATGATGATTTTCGCTATTTTTTTAGTGATTTTACTGAAAACAAATGCTGA AGAAACAAGTCCTTCTAACGAAAAAGGTACATATCAACTTGCTACAATAT ACAGCACTAATGCTTCTTCTTATGACAATAATGAAGCAATTAATACGATG CTTATACAATCAGCAACTAAATTTAATAAAGCTAAGTTCTTCACAGAAGA AACACGCATTAATGAAGACGAGTATTATGAAGAAGCGATTAATTTGAAAA AAGATACTTATCAAGAGTTAATATATTTAGAATTATATGATCCAAAAACA GAAGAATTTATCAATATTAAAGCTGTAATGATGGAAGCTTTACGTGGAGA TTTAAAGTTGAACGCAGAGACAGAATTCATTAGTAATGACGAAAATTACT ATAAAAATAGTGATAGTCCATCTTTCCACGTGCCTAAAAGTTTAACTTTA ACAGAAATTAAAAAAGCTAAAATTAAGCAGCTAGGATTTGAACTTCATTA TAGTAATACTTTGCAATCAAATCAGGTAGAAATAGAATTTAATCCTAGCG TGTATGCGCAAATTTTGAAAAAAGTAAATCAACAAGATGTTTTAATTACA GAAGCATACGTGCAATTAAAAGCTCAAGAATCATTTTATGATTTCTTAGC AGAAAATAAACTATATGCTAAAAAAATATTTATTAAAGGATATGAACCAG AGTTATTAAATGCTGAGGTTAATCAATACAGTAATGCAGTTATGCTGATA AAAAAAGTAGCACTTCTTATATGCTTACTACTCTTAGTATTATTAATTTT ACTAATTATGTATGAGGTTAGTTATAAAAATAGTTATAGTACATTGACTT ATTATGGCTATAATGAAAAAGAGCTACTTCAATTCAGAAAAAAAACGTAT CTTATTACAAACTTTAAAATCTTTTCGGTTATTAGTACTGTTATTTTTCT TTTAATTATGTGGAGTATTGTTCATTCGGTACTTATTACCGCCATAATAG GTGTAGTAATGAAATTTTTCTTTTTTGCCTACATCGTCATACCATTAATA ATTAAAAACAACATTAGAAAGGCGATTATATGA ORF1228 (SEQ ID NO:6) AAAGGCGATTATATGAATAAAATAAATAAATTTAGCATTTTTTCTATCAC TAAACCAGGTATTTACACAATTACAGGTAGTAACGGAAGCGGAAAAACAA CCTTTATTGAAAATGAATTAAAAAATAACACAAATAAAGTAAAAGATGTA GCTTACTTTGCGCAAAAAAATTGGAAATATAAAACTAATGTAGAGAAATA TTTACACTTCCCAAAAACTAATCCGAGCTTAGTTCAAAAGTATTGCGAGT TGTTTTCTGTAGATAACTACTACTTAGAAAAAGATATCCAATTATTAAGC GGCGGAGAATTTGTCAAAGTAGAATTAGTGAGAACATTAGCTTTGGACTC TTCTATAATTATTCTAGATGAACCTACAAATAATCTAGATAACAAGTCCT CGGAGATACTTGCTAATATTTTAAGTGAATTAGCAAAAACGAAAATTATT TACTTAGTTAGTCATGATACTCGATTGGAGCATTTTTTTGATAAAACTAT TTTTGTAGATAAAGATAGGATAGAAGTATCGTCTAATGTTGAAATAGAGC AGAACGAGATTCAAGTTAATAGTAAAAGAGTTGTTTCAAATGGAAGAATT TTAAAATATTTACTTAGTTCAAAATTTAACTTCTTGATGTTTGCGTTTAT TATAGTACTAACGATCTTATTAACCAATATTACCTCCACTATTATTTTAC GCTCAGTTCCAATAGAAGAGAATTTAACTAGTGATTATAACTTTGAGTTG ATGGATATTGCGGAGAATTATTCTAGATATTTTAATATTGAAATGACGGA AAGTGAAATTGAAGCTGAATTTCAGGAACCTAATCATCTCACTACAAATG AGTTGATTGAATTACAAGACAAAGACTATATCAAACAAATTTATGTTGTA GATGAAAGCTATATAAATGAATTTGTTTTGGATAATTCCAAGTTTGAAGT TTTGGCTCTTCCGGAAATAATTACAGACTCGCCTAACTATGTAAATGCTT TTCCTGTTACTAAAATGCACTTAACCAAAGGACGTTTTCCAAAAGACGAT GCTAAAGAAATCGCGTTATCTTTTGCTCAACTGAAAAAATTTTTCCATGA TGATATTAGTGAAGAATCAGCTATAGGTAATAAATTAGAATTTGAAGATG AGTTGTATGAAATAGTCGGTATCGTTAACTCTCCAGTAGCAGCGATCTCT TATTCGAAACAAGTGAGTAAAGGAACTGTTGAGGTTGAGGATAAGACTTC TGAGAAATTAAATAATATATTGTTAAAGCTTGAGAAAGAAAATTATGATA ACCCTAATTTTTCTATTATTTCCATTAAACTAGCTAGTAAAAACCAACAT GAACTCTTAAACTATTTAAAAGTTCATGGACCAAGCTACCAATATGCCTC AAATTATGTGGATAGTATTTCGCAAGTAGCTTTTTATAAACAAAATTTAG CAAAAATACTTCTTATATCAGTAATTTTTTCTCTTATAGTATCTGTGTTG ATTTTTATTTTTGGAAGAAAATCATTTAGTTTAATTAATGGCTTTTTAAA CGATATGTCTAATTTGAATTTTACACCGAGAAAGAATAAACGGTTTATTT ATGTAATAATGATATTAGATTTTTTGTTGAGTATGCCTGCGTGCTTGTTA GTAAGTCGAGTTATTATTGGGGATAATATAGGTATGCTAATGATTCTTCC GACACTGGGGGGTTCAGCTATCATATTTATGCTCACATTACTATTAATGA GTTACCGGGATAAGAAGAATGATTTTAGAAATTTATAA ORF1272 (SEQ ID NO:7) AGTAGACATGTCATTAATTGTAATTTTAGGAATTTGTTTTATTTTATTAA ATCCAATAAAACTAGCAATAAGGTTTCAGAATTCCAATATTTGTTGTATA TTTTTTGTTTTCAATGGTTAATTCTCTTGCTTATAAGATTCTTTTATTTT AGCTTGTTTTATTTTTTTCAAAATAAAGTTAGTTTCACTCATCAAACTAT AACTAAAGCATATGTTTTATTATTTGTTTTGTGGATTGCTGTTTTTATTG TTTGTTGTTTTCGTTTTAGAAAAAAATTAAGAAAGGGTGATTTTAGAAAA GATTCTGTATTACAAAATAAACGGGGTAACTTAGGATTGAATTTAAGCAA AAAAACATACATATCAATTGGAGCATTTTTTGCATTTATATTACTAGCTC AACTTATTGGAGGAGTAATGATATATGTATTCTTTATCTCTATAGCGGTT TTATGTATGGCATTATCTTTTCTAGGATTAGTGATCTTTCCTGAACAAAT TTTCACTGCTTATTGTAATTTTAAAGAATTTCATATCGAAGAATAG ORF1384 (SEQ ID NO:8) AGGAACGGCTTTAATGTTGTGGAGCCGGACTTTGCTTATCAATTTGAAAC GAGAGAAGAGATGGTTGAAAAAAGCAGTTGGTATGCGGAAGATTTTGATA TTGTTGCTAGTTTGGAAGAAAAGTACTTAGCTGGATTCTATCAAAATCAA GTCTATGGTTACGTAACTCCAGTCGAGTTTCAAGAGGAGGAAATGAAAAG AGCGATTCCAAGCGAAATGTTTGTTCCTTTGAAAGGCTTAGAAGTTTCTG AGTTGGCGGATTGGGCAGATGGTTTTCCTCCTGAATTGCAAGAACGGTAT AATGAGCTAGCTGAATCAGTGGAAGAGTAA ORF1385 (SEQ ID NO:9) AAAGGAGATCATCAAATGAGTATTACAGAAGAAGAATTTGAAGAACAGGT TTCGGAGTTGTTTATTAATTATTTAGAAAAATGTACGCCTGAAGAGATTC ATCAAGTGGTTGTAGAATGGAATTTTGATAATCCGAAGAAACCGATTCAT TGGATTGCTAATTCGACGAAAACGGATAAAGGAACGGCTTTAATGTTGTG GAGCCGGACTTTGCTTATCAATTTGAAACGAGAGAAGAGATGGTTGAAAA AAGCAGTTGGTATGCGGAAGATTTTGATATTGTTGCTAGTTTGGAAGAAA AGTACTTAG ORF1386 (SEQ ID NO:10) TCCAGCACAATAATTTTAAAGGAGCGTAACTTTATGAACGAATTTCCAGT TGTATATGAACCAGAGTATATGACCATTTATTTACTTGTTATCATCGGTG TCTTTTCTACAACATTGGCTTTATCGCTTGAAAAATATAAGTTCACTTTA GCGGGAAAAGCGTTGATTGGGATGTGTTTTATTTCTCTAGCTGTGTTATT TATATATGTTTTAGAGTTAGCATATCTTTCAGATATAGCTGATTTGTTAT TTCATACAATCGGTGTTTGGGAAGTAGTGCTTTTCACACATCCATATATT TTCTTAATACTTGCAATCTTGCTCGGCGGGGAAAAGAAACCGCCACATGT ACCCAAACTTAAAAAATAA ORF1387 (SEQ ID NO:11) ATTTTACTACCATATTTATACTCAACCAAAAAAGAAGGAAAAAACATGTT ATCCGATATCACAATTACAATTCCTAACAAAACAGCTCAAACAAAATACG ATAATCTAGCAAAAAACATGTCTTTTAAATCAAAAGAGGATTTGGAGTCA TTGCTTGATTTGATCAAGATTTTGTATATAAACAATTATTATGAAGAGGC GCTTTTGTGTTGCCGACTAACGAACGACGTAGAATTTGATAATGATTTTG ATGTTTGGACATTTATTCATAGGATTTGGATGTTTGAAATGCAAATACTT GTGCATTTTGGGGAAAAAGAAGAGGCCGAAGAAATTGCCACTAAAATAGA GGCGCATTTTAAAATTCCAATGAAAATATGGAATACTCCTGAAAAAAGAT ACGCGCAGTATAAAAAGAATCGTTCTCGGATTGTTCTTAAGGATCTTAGC TATGAAGAAAAAATCAATAGCACACCTAGAGGAGAATCTGGAACATTTGA TTGGAAATTTGTCGCATTATCAAGTCTTATCAAACCAATTACTTTGAACA ATATGACTGGTGTTTCGGTAGAAGAAGCAGAAGAAATATTTAGACAATAT TCAGCAGAGTTACAACAAACGAAAAAGTATGGAGTTTCGTTATAA ORF1388 (SEQ ID NO:12) TTGTTATATAGTTTCCAAAAATTTGATTGGCTTATTGGTTATTCTGATGA TGGCGATTATGTTACTTGCGTAGATAATGGACTGTTCTTTTCTATAGATA AAATGGTCCTTCTAGATAATGATATAAACGTACATCTATTGCCAGTACAG GCTCACTAA ORF1389 (SEQ ID NO:13) AAAAAAATAGAAAATAAAATAATCTCTAAATTTATCAATCTGGAAGATGG TTTTGATTTTAATTTGCATCGAGCGTATTTGAGATATAATCATAAATTAA GATGTATTGGAATTAGTTATCAAAAAAATGATTGGTGGGAATGGTTTAAA TTAGTTCCAAGCATTGTAGGACAAACAGCACCTGTATATGTTGTTTTTAC TGGTGATAATTATACATGGATCTATACAGGTTATTTAGAGGCGTTAATGA AAATTTTATATTATGGCAGTCCTATAGGTGAAGGTGATTGTTATATAGTT TCCAAAAATTTGATTGGCTTATTGGTTATTCTGATGATGGCGATTATGTT ACTTGCGTAG ORF1390 (SEQ ID NO:14) TTATATAAAAGGATATTCTTAAAGCATGATATAATTATTTTAGTATTAAA AATTTATTTAGGAGGAATTAAATTGAGATTAACTAGATTAAAAATTACGG ATTTACATAGTTCTTATAGTTATGACATCGAATTTAATAAAGACATCACT TTTTTTTACGGGACTAATGGTAGCGGAAAAACAACAATATTAAATATTCT TTCTAGTATTGTAACAGGAAAAATTTATCAACTATTCACTTATGAATTTA GTTCAATTACTCTACACTATTGTTTTGAAAGAACAAAAAATAAAGAACAA AAAATTGAAATACTTAGAACTACACCCCTATGTATTGAAGTTACATTCAA TGGTCAGAGATATATTTTAGAAAAATTTAATGAATCTTTGAGTAATTATC GTCAATCTATAAACAGAAATCTAGAAAAAGACTTTTTTGGTGAAAATAAA TTTTTAAAAGAAATAGCAGATATGTTTAACTATGTGTACCTTCCACTAAA TAGACATATTTCATTAGATAATAATATGTTATATGATAATAGATTACATC GTGAAAGAACAATAAATGCAATGATGCATGGAGTTGAGGAGGATGAAAAT GATTACTATATGGAAAGAGATAAGTCGATGAAGAAGGTTCAATATTTAAT AAAGACAAAAGTAATGAGGAATAATACTAGAATCAACAGACTAAATGATA ACTTCAGAAATCAAATACTAAGATCCTCTATAGATATACACAAGCTTACT TTTAGTATAGAAGAAATATTTAATGAGGTTAAAAACTTAAAAGTAGAAGA AATCAAAGATATCAAAACATCTTATATAAACATATTGAAAAATTTGAATC AAATAACCCAAATTGAAGAAAAAAATTATGTTAATTTTTTTGATAATTAT ATAAGAGAAATTAAAGAGAATGAAAATATTGAGGATAATTCAGTTTCAAT TCAGTTGATTTTAAAATATAATGAAATAGCAAAAATAAAAAATATAGTAA AACTAGCCGAGGATATGGAAACTAAAAAAGCAAAAGTAGTTGAATCTGTT AATTTATTTTGTGAAACTATTAACAGTTTCATATCAACCGATGGTACAGA AAAAAAAGAAATATTAATTGATGAAAACGGAGGTATATATTTACAAAATG TAATTGAAAAAAAACAATTAAGTATATATAAACTTTCTTCTGGGGAAAAG CAAATTGTAATTTTTTATGCAAACTTAATTTTTGGAGTAAATGAAAATAA AAGAGGTATATTTATTGTTGATGAACCTGAACTATCGTTACACTTATCTT GGCAAAAATTATTTATTGAAAAAACTATAGAATTAAATAAAAATATACAA TTTATATTTGCTACTCATTCGCCAGAAATAATAGGTAAATATTATAATAA AACATTCGAGTTAAAGAAAAAGATAGATAGATAG ORF1391 (SEQ ID NO:15) GAGAAACTCAATAATATGAATCAATTACAATACTCTGAAGATGCTTTAAA AAATAGGTATCTCTTTTTTAAAGAAATAAATGAAATAAATATTTTTGTTG AAGATAAAGGAAAAGAATATGAATATGAGGAAATATTGTCTAAAGTTTTT GCTGATGAATATCATATACAGACGATATATGCACTGGGGGGTAAACCACA AGTTTTATCCGCATTTAGAGACTGTAAAGAACATGTTTCTAGCAATAATA ATATAAAAAACATATATCTTTTAGATGGTGATTTTGATCAATATTTGGAT AATATAGTAATGGAATCACATCCACATATTATTTATTTGCAATCATATAA TATTGAAAATTATTTTTTGAATGAAGAATCGGTAGTAACTTTTATGCAAG GAAAAATGAAAATGCTGAAGAATGATGTAAGGACTAAAATAGCTTATTCT GAATGGCTTTCTAATACATTATACAATATAGAAAACATTTTTATTTTATA TTGTATAATTCAAGAAAAGGAATTAGGGATTCCTAATGTAGGGGATTCTG AATATAAAGTAATTAATATGATCGATGGATCTATCAATATGACGAGATAT GAGGATTTGAAAAAGCAAATAAGTAATTGTACAGTAAACATAGATTTAGT AGAGCAAGAAATGAAAGCAAAAATTCACAATATAAATCCTAATGTGTTTG ATTTGATTTGTGGTAAACATTTGATTTGTAGTTTGTACCGTCATCTGTTA AAAATAACTAAAGGTTTCAGCTATGATGAATTTAGATGGCATTTAGTTCA AAATGTTGAAGTATCTAGACTTAATTTTATAAAGGAAAGAGTTGCTAATT TGTAA ORF1400 (SEQ ID NO:16) ATGAACAGTGATTCAAATAATAACATCAATAAGAATCGAGAAGCGGGAAT AAGTATTATTATTCCATTATATAATGTGGAGGAAGTAATCCTGGAAACGC TCGAAAGCATCCATGAGCAAACATTTGACATGTACGAAGTTTTATTAATT GACGATGGTTCAACGGATAAAACAATAGAAATGGTGACAGAATATATATC AGATAAGCCAAAATTTCAGTTGCATACTCAACCAAATGGTGGACCAGCTT CGGCTAGGAATTATGGGTTGCGTCTTGCGAATAGAATGTATATTTGCTTT GTGGACAGTGATGATATTATTCCGAACTATGCACTTCAACTAATGTATGA CGGTGCAATATCCACTGGTTCAAAATTGATTACAGGTGCAACGAAACGCT TTAATTCAGAAGGTGAATGGTTCATTCCGATGCATATCCAATATAATATT GCCAAGCCAGGAATGAAAACACTACTGAAAAATCCCGAGCTATTTTATTC GATAGGTCCTTGTGCGAAACTCTATCATCATTCTTTGATAGATGGTGTGT TTTTCCCTGAAAATATTCGTTACGGTGAAGATCAACCATTTGTTTTGCAT GCTTTACTTCAAGCAGAAAATATCTATACTGTAGAAAAAGTAGTTTATTA TTACCGCTTACGTGATGGTGAATCGCAATCATTAACGCAATCTGTAAATA AAGATCCAATTCGTATTTTAAAATCTGTTTTTCAAATATTTGACTACGGG GAAGCAGAGTTACTCAAAAATAATACGGAATATGAAATAGCTTTAAAATA TTATCAACGAGTATCTAGTGTTGAGCTTTGGGGCGCTTTAAGGGCGGCTA TTGAAAGTAAGAAAAGTGAAAACCAACAAATTGCTTTTACGATGACATTA GACTGGTTAAAAACCAAATCAGATGACTTCCTAAATATAATTCCTTCCTT TAGATATTTCTTGTTGTTCAGTAGTATCGAACGTGTTCGCTATATTACAA GAGACAATAAAGAAAACTATCGCCAACTAATTACGTATTTGTGGGAGAGA CAAGGGGAAGAAGCAAAAATTGCATTTAGAAAAGCATATCCTATCCATAT GAAAGCTGCTTTACAAATTATGGAACATAATAATTGGGGAGCCGCTCGTA AAATCTCCTTTAAATTTATTATCCGTCGTAAATTTAAGGCGCCTATTCTA ATTCGGAAAATAAGCAGAGGCATTATATTTAGACTAGCTACTTTGATGCC ACGCAAAAAAGACCAAGTTATTTTAGCTACAGAACGTAGTACAAGCTTAG AAGGAAATTTATTAGCCATTTATGATTACCTGTTTTATAATGATATGCCA CAAAAAGTCTATGTGTTTTTACGGAAAAATCGTAATTGGTTTGAAATGTT CCAATTGTATTATGCATTAGGGCGAACTAAAACAATTGTATTAGATGATT ATTACAACAAAATTTATGGTTTGAAATTTAATAAAAAGACACATGTGGTA CAATCATGGCATGCGACAGGGGCTTTCAAAAAGTTTGGCTTTAGTGCGCT TGAAGGTACAGATGCTAATACAGAAGAATTTGAGACACGTGCTCATTCGC CTTACACAGATGTTCTTGTTAGTTCAGAAGGCATAATTCCTGAATATATG GAAGCTTTTAGAAAACAAGCTAATCAAATTAAACCTATTGGTGTGCCTAG AACAGATGTGTTTTTTGATCAAGAATATGTGGCATATACAAAAGAAAAAT ATATGAAAATGTATCCGCAACTTCGCGACAAAAAAGTGTTGCTATATGCG CCAACTTTCCGCGGTGGGCCAAATGAACGCTTTAATTATAGCGTTGTACT TGATATTGCTGCTTTGAAAAAAGAACTTGGTGATACACATATTTTAATTT TAAAATTCCATCCTGTTATTAAGAACGTTTCATTTAATGTGGATGAAAAT GATCCATTTATTTTAGACTTGACGTTGAATAACGATATTAATGATTTAAT GTTATTTAGTGATGCGCTTATTACAGATTATTCTTCGGTTATTTTTGAAT TTAGTTTAATGAATAAGCCAATTTATTTCTTTGCATATGATATTGATGAT TATTTGGATGAACGCGGATTTTATTTCGATTACAAAGCAACTATTCCTGG TGAAGTTTTCAAAGATACGCCGTCGCTCATTGAGTCGATTAAAACGGGAA AATATAATTACGACGAACTGGAAGTCTTTAAAAAGAAATTTGTTGGAAGC TTAGATGGTAATTCAACGAAGCGTTTTGTAGAGACCTATATTGTTCAAGC AAATGAGGAAGTGAAAGATTTATGA ORF1445 (SEQ ID NO:17) ATACCTCGTTTATTTCTAAATTTATTCACGTTTTTTTCATATTTGAACTC TAAAATAAAAGGTATTATCTTATGGAAAGAAGTGAAGAATATGAAGAAAC GGATACAACATTTAGATTTTTATTTTGTTGGAATTATTGTTATTGCCATC TTTTTTAATTTTTATGGTATTTGGAATGATGATACGGTAAATCCTTATTA TACAGCTGCTGTGACAAGTATGGTGCAAAATATTCATAATTTTTTCTACG GAGCTTTTGATCCTGCTGGTTTTATTACGGTAGATAAGCCACCTGTTGCA CTTTGGTTGCAAGCGATCAGTGCCCTTATTTTCGGCATACATGGTTGGAG TGTTATCTTACCACAAGCGTTGGCTGGTGTTGGTTCGGTGATTTTGCTTT ATGTGCTCGTCAAACCTAGATTTGGCGCATGGGCTGCAAGAATTACTGCT TTGATTATGGCGCTGACTCCTATTGCGGTAGCCGTGACGCGTACTAATAA TATGGATGCTATTCTTGTATTTGTGTTATTACTAGCAACCTTTTTCCTTT TTAAAGCTGTTCATCGTGCAAAAATCGGCTGGCTTTTACTTTCTTTTGCG TTGATTGGTGTCGGTTTTAATGTAAAAATGCTCCAAGCTTTCATGGTCGT GCCCGCATTTTTGCTCTTCTATTTTATTGCTACAAAACTAAGTTGGAGAA AAAAGCTAGTTCAATTAGTAATCGCACTTGTCTTAATGCTAGGTGTCTCT GTTTCTTGGGCAGTCGTAGTTGATCAAACAGCTGCTTCAGAGCGACCTTA TATCGGTAGTAGTCAAACCAATTCGGTGCTTGAGTTGGCATTTGGCTATA ATGGTATGGAACGGCTTCTTGGTCAAGAAACTGGAACAGGTAGTAATGGT AATGTGGAAATGGGGACTCCTCCTAGCACTAACTCAACAGATTCAAGTAA CGCAACCCCACCGACTCCTCCAAGTGGAAGTATGCAGGACGGTGCTAACG GCGGAACTCCTCCTCAAGGAAATAATGGCACTCCTCCAACTGGAGCTCCC AGTAATGCGGCAAACGGCGGCGGGAATGGATCAAAAATGACTGGTAGCAC AGGCATGTTTGGAACAGGGAACGCTGGACCACTTCGTCTATTCCAAACCG CACTTGGTGATCAAATTAGTTGGTTCTTACCACTTGCTATTATCGGTATG CTAGCCATTTTCCTGGTGTATCGAAATGAAAATAAACGAATTTATCAATT GACCTCCAGACAAAAGGAAATAGTTTTCTGGGCAGCTTGGCTTATCCCTG TCGCCGGATTCTTTAGTATCGCTGGCTTTTTCCATCATTATTATTTGATT ATGCTAGCTCCGCCAATTGCTTTACTTAGTGGCGTAGGTCTAGTGGCGCT CTTTCGGTTATACCAAGACAAAGAGAATTGGCAAAGGTTCCTGCTACCTG CTGCAGTTACGCTAACTGGAGGTCTACAAGCATTCTTTGTTGCTGCTTAC TTGCCTGTTTTAGCGGTAGTTATTGGTATTGCTGCACTAATTACGTCTAT TATCTTAATTGTACTTAGACCACAACCTTCCAAACTCACCGCGAAAATAA CAGCGCTCGCTTTAGCGATTTTGCTCATTGCTCCAACATATTGGTCTTTA ACACCTATTTTATATGGTGGGAATAGTTCCTTACCCGAAGCTGGACCACA ATTAAAACAATCTAGTGGTGGTGGATTCGCCGATGCATCTGTTGATAGTG ATTTAATTAGCTATTTACAGAAAAACAATACCGGAGAAACCTACTTATTT GGGACAACAGATGCAACAACAGCAGGTCCTTATATTATTAAAACGAAAGA AGCTGTTATGGCACTTGGTGGTTTCAATGGAACAGATCCAACTCTAACTG TAAAACAATTAAAACAAATGATTCAAGCCGGTGAAATAAAATATTTCTAT CTCCCATCAAATAGTAAAGCTTCTGACTCAGATGTGGTAAAATGGATTCA AGAAAACGGTACAGAAATTGATAGTTCGAAGTGGAGTAGCTCCGGTTCTA CGGATGATGACACCACTTCTAGCGCTTCTTTTAATATGCAAGGTGGCGCT CAAGGAATGAATGGCACTGGTACAGGAACACTATATCAATTAAAATAA ORF149 (SEQ ID NO:18) GCTTTTAAATTTTATGAAATGCCTTCTACGGATATTGCTTACTCAAGGAC CGGGAAAATCACTAACACTTCTGGACATGCAGTATGGACTCAACCTTGCG GACAAATAAACTCTACTTTAAAAGGACCAGCAAGTGATTATCTTAACAAA GAAATAACTATTTGGAGAAAAGTAGAAAACAAAAGAGGTACTTATTATCA ATTTAGTGAAACCAAAACTCCTAATATAAAAGCTTGGTTAGATGCAAGAG CCATAACACTCTATGACCAAGTACATTTTAATGAAGAGTACAATCAGATG GCAGTTATATCTACAGTTATTGGACATGCAGTATGGTCAACACCTTATCT TCAGTCCGATAGTAAATTAATTGCGCCTGCTTCTAATTATGAAGGAAAAA GAGTTGAAATAATCAGAAGAGCCAAAACAACAAGGTCAATATATTATCAA TTTAGTTATGATAATAAAGTAATTGGTTGGTTAGACACTAGGGCTTTCTC ATTAATACCTTCAAACACTGCTATGGTGATAAGTAATAGTACAAACGACA TTTTTTCAAATATAACTGATGCATATAATAAAAAAACCCTATAA ORF1490 (SEQ ID NO:19) GGAGCTGGAATAATGACAAAAGAAGCAGAAATTGGAAAACAAATATTTAT TCATGTCGGTGGAATGGAAAACGTTTCAAGAATTGCACATTGTATGACAC GAGTTCGATTGGGGATAGTTGATAGTGACCTTGTTGATGTAGCTGGATTA AAAAAAGTTCCGGGTGTTATCGGTGTTGTAGAAGATGATACTTTACAGAT TATTGTTGGACCAGGAGTTGTGAACAAAGTGGCCGGCGCAATGGCAGAAA TGGCTGGTGTTAAAATTGGCGAAACGATTCAAGAAAATTTGGATAGCGGC ACAAAAACTGGTAAGGAATTAGTCGAAGAAAAAGCATCCAAAACAAAAGC TGAATTAAAAGCAAAACAAAATAATTCATCTGGTTTTAAAAGATTACTAA AATCAATCTCTAATATTTTTGTTCCACTAATTCCGGGTTTTGTTGGAGCG GGATTAATTGCTGGTATTGCAGCAATTATTTCTAATAATATAACAGCTGG AAATTTAGATGCTGCTGTTTGGACTCAATATATTGATATTTTAGGAGTTA TTAATAAAGGAATATTTGCCTTCTTAGCTATTTATGTAGGGATTAATACC GCGAATGAATTTGGTGGAACACCTGTACTCGGTGGTGGAATCGCTGGGAT AACATTGCTTTCCGGATTAGCAGAAGGACATACAATTACAAACATTTTCA CGGGGGATCCTATCGTAGCCGGACAGGGTGGCATTATCGGCGTATTATTA GCAGTTTGGTTAATGTGCGTACTTGAAAAAAACTTGCGCAAAATCATTCC GAATGCGATAGATATTATTTTTACGCCAACGCTTGTATTACTTATTATTG GTTTAGTAACTATTTTCTTAATTATGCCTTTTGCAGGACTTGTATCAGAT GGTTTAGTTAACGGTATTAATTGGGTAATCGAAGTTGGAGGAGTATTCGC AGGTTTTGTGCTAGGGACGTTATTCTTACCAATGGTTATGTTTGGGTTAC ATCAAGTTTTAACACCCATCCATGTAGAAATGATTGCTCAAAATGGTTAT ACTATCTTACTTCCTATTCTAGCTATGGCAGGTGGCGGACAAGTTGGTGC AGCAATCGCGCTTTGGATTCGTTGTCGTAAAAATAAACCACTTGTAAATA TGATTAAAGGGGGTCTACCGGTTGGAATTTTAGGTATCGGTGAACCATTA ATTTATGGGGTAACAATACCACTTGGGAAACCTTTTCTTACAGCTTGTCT CGGAGGCGGTATCGGTGGGGCAGTAATCGGCTACTTTGGTAACGTCGGAG CAATTGCAATCGGCCCATCAGGAGTTGCACTTATCCCACTAATCGCGAAT AATGAATGGCTTTCTTACGTCATCGGATTAATTGCAGCATATTTAGGTGG ATTCATTTTAACTTATTTCTTTGGTACACCAAAAGACGCAATGAATAGCG TAGAATTGTAA ORF1491 (SEQ ID NO:20) ATAAAAATTTTAATATTAAAATTATATATTGAAATTTTATTTCATTTATA TTATACTGTGTTGGAAGGAGTGGTTAAAATGTTAGAGAATTTAGCAACAG AAGAACGAAATGAAAAAACGATTGACTTAGACACACTTTCTCCAAAAGAA ATTTTAGCAGTAATGAATGAAGAAGATTTAACAGTTCCAATAGCTATAAA AAAGGTCTTACCTCAAATCGAGTTAATTGTAAGCGGTGTCATCTCGTGCT TTCAAAAAGGTGGCCGTTTGATTTATCTTGGTGCCGGAACAAGTGGAAGA TTAGGAGTACTTGATGCAGCTGAATGTGTTCCAACTTTCGGGGTCTCAAA GGAGCAGGTCATTGGCTTAATCGCAGGTGGTGAAAAAGCTTTTGTAGCTG CAATAGAAGGTGCGGAAGATTCAAAAATACTTGGCGAAAACGACTTAAAG CAAATTAAGTTAACTGCAAACGATTTTGTTATTGGTATTGCTGCAAGTGG TAGAACGCCTTATGTAATTGGCGCACTTGATTACGCCAAATCTGTCGGGG CTAAAACCGGAGCAATTTCTTGTAATGCTAATGCAAAAATTTCAGCGCAC GCCGATATAGCCGTAGAAGTTGTGACTGGAGCGGAAATTTTAACAGGTTC TACTAGGTTAAAAGCAGGAACAGCTCAGAAACTAGTATTAAATATGATTT CAACAGCTTCAATGGTTGGAATTGGAAAAGTGTATAAAAATTTGATGGTG GACGTTTTACCAACAAATAAAAAATTAGAAGAGCGCTCTAAACGAATTAT TATGGAAGCTACAGAGGCTGATTACGAAACAGCAAATAAATTTTATGAAG CAGCTGAAAAACATGTCAAAGTTGCCATTGTCATGATCTTAACCAATTCA ACCAAAGAAATAGCGTTAGAAAAATTAAGTGAAGCAAAAGGGTTTGTTCG AAACACCATTCAAAAATAA ORF1492 (SEQ ID NO:21) CTAATTTTTTGGTATAATTACGGAAAATGGAATGGAGAAAAGTTAATGAG TAATGGTAGTATTATCAATCGAATAGAAGGTATTTTAAATGATTTGCCGA AGTCAGAGAAAAAAATTGGCCAAGCAGTATTAGCAAATCCAGAATTTACA ACTACTGCATCGATTCATAAACTAGCTCAAAAAGCAGATGCAAGCGGTGC GGCCGTTATCCGTTTCTGTAAATCAATCGGACTTCAAAGTTTTCCAGAAC TAAAAAGACAATTATCATTAGATTTGGCTCAACCGCAAAAGAAAGGCTAT TATGATATTGAACCAAATGAAGATTTTCATACCATCACAGAAAAACTAGT TTCCAACATGATTCAAACGATGAACGATACGGCTAGCCAACTAGATGAAG CCAAAGTTTTAGAGGCATGCGAATTACTCGGCGAAGCAGATACTATTTAT ACATACGGGGTCGGGGCTTCTTGGTTAGTAGCAGAAGATATTTCACAAAA GTGGCTGCGTGCAGGGAAACATGTTTTAGCTACGCAAGATGCACATGTTC TAGCAATGGCTTTTGCAACGGGGAAGAAGAAAGCCGTTTTTATTGCTATT TCTAACAGTGGAGAAACATCAGAAGTCTTGCAACTCGTTGATCAAGCCAA ACTGAACAACGTCATTGTTATTAGTCTTACACGTTTTGGTAGCAATAAGC TGAAGGAAAAAGCAGATTTATCTTTAGAAACTTCTCGTGCTCCGGAAGCT GAAATTAGAAGTACAGCAACAAGTTCAAGACAAGCACAATTGCTAGTAAT TGACATTTTATTTTACTATTATGCATCCCATCACTACGACGAAATGATTC AACAAATTAAACATTCTCGAGAGGCCACGAATCGTTTTAGAGAATAA ORF150 (SEQ ID NO:22) TTTTGTAATATAATACATATAAATGAAAGAGGGAACAAAATCATGTTAAA GAGAAATGTACAAAAAGGGATGATTAGTTTAATTGCAATTATGATGTTTT TATCAATGTTCAGTTTTACAAATTTAAATTCTATTAAAACTGTAGAGGCT GCAACAACTGCGTACAATACAATTGAGTACAATAAATCAGTTAATTTAGA TGCTAATATTGCATATCCAGAAACAAATGCATTTTGGTCTGCACCATATT ATTCAGAAGGATCAACATTTATATCAAGTGCAACTGCACCTTCTTATGCA AAAAAAGATGTTAAATTAATAAGAGAGGCAAAAACTGAAAGAGGAATTTA CTATCAAGTAAAATTGGGAGACAAAATTATTGGTTGGCTTGATAAATGA ORF1504 (SEQ ID NO:23) CGAATAAATAATTACGAATACATTTCAAAAAACAAGGAGGAAATTAAACA TATGCAAAAAGCAATCAAAATAATGTTAGTTTTATTTTTAATGACAACCG TATTTTTACCTTTTAGTAATGTTCGGGCAGCATCAACTGATGTAGTAAAT ATACCAGATCCGTATTTAAACGAAGGTCTTAAGAGCATCGTAGGAAATCC ATTCTTAACCGAATTGACTGAAGCGAATCTTGAAACCATTAGTGTCGCTG ATATCTCTTATATGAATGGAGTACCTGGTTATGCTGTCACTGGTTTAATT AGTGATTTAACCGGACTCGAAAAAGCAGTTAATATGACCAAATTATATTT TTCAAACCAAACAGAAATTAAAAATTTAAATCAAATAAAAGATTTACCTA ATCTGAAGAAAATTGTTGGTGTTACTACAGGTTTAAATGATATTAAAGCC CTTGGTGAAATGCCCGCACTCGAAGAACTAGAATTAGGTGGGGATTATAT TACTGATTTCACTCCCTTACTTGAAAAAGATAATTTAAAATCATTTTCTT ATAACTCGTATGCTTGGTTAAATCCAGCATATCACCAAATTGATAATGAA GAATTTAAAAAATTTACAAACCTTAAATCACTCGAAAGTTTAGATGTAAC TTGGAATAACATTACCGACTTATCATCATTAACTGCAAATGATCATATTA CAAACTTAAATCTAAGTTACAATAAGTTCACTAATATAGCTCCAATTGCT ACAATGAAAGAACTTAAAGTCCTTTATTTAAACAATAACAACCTAACTTC CATTGATTCTTTAAATACACTAAGAGGATTAACTATAGCCTATGCTGATA ATAATAACATTACTGATTTGAGTAATTTAAAAGACTTTTTTGAAGGCATG GATGTCGTTGGAGATTATAAAGGTTTACAAGTTAACAACCAAACTATCAC ACTTCCAACTATTAATATCAAAGAAGGTGGAACAGCTATTTCAAATAACC CTACTTTAGATATTGATGGCGAAAAAATGCCTGTTTCTAGCATTTCTGAT GGCGGAACAGTATCTACCGATAATAAAACCGTTTCTTTTACTAACTTACC AGTTGGAAATAAGACTGTTACTTATAAAGCAACATTCACAGCTACCTCCA CTAAAGGAGTACCACTTAGTTATTCTATTAAAGTATCGCAACCAATTAAT GTATCTGCACAATCCGATTCAACAGTAAACGTATTTTACAAAGATGAAAA TGGCGATGAATTAGCTCCAAGTGAAACAATTTCTGGTAAATCCGGAGAAA ATTATCAAACAATAGAAAAAACAATTACTAACTACACATTAAAAGAAATT GAAGGCCAGCCTTCAGGACAATTTGGCGATAGTGATGCAACAGTCACTTA CGTTTACGAAAAAGCAGACGGCGCTCCTGTTACCGTGAAATATGTCGACG TGGATGGCAACGAATTAGCTACTTCCGACACACTGAACGGCAAAATTGAT GCTCCTTATCAATCTACAGCCAAAAGCATCACTGGTTGGACGGTCAAAAC GACTCCTGCCAATGCAACGGGCGTATTCACAAACGCTAACCAAACGGTCA CTTATGTGTATGAAAAAGCGGATGGCGCTCCTGTTACCGTGAAATATGTC GACGCGGATGGCAACGAATTAGCTACTTCCGACACACTGAACGGCAAAAT TGATGCTCCTTATCAAACTACCGCTAAAAGTCTTTCTGGTTGGGCAGTCA AAACGACTCCAACCAACGCAACGGGCGTATTCACAAACGCTAACCAAACG GTCACTTATGTGTACGAAAAAGCGGACGGCGCTCCTGTTACCGTGAAATA TGTCGACGTGGATGGCAACGAATTAGCTACTTCCGACACACTGAACGGCA AAATTGATGCTCCTTATCAATCTACAGCCAAAAGCATCACTGGTTGGACG GTCAAAACGACTCCTGCCAATGCAACGGGCGTATTCACAAACGCTAACCA AACGGTCACTTATGTGTACGAAAAAGCGGACGGCGCTCCTGTTACCGTGA AATATGTCGACGCGGATGGCAACGAATTAGCTACTTCCGACACACTGAAC GGCAAAATTGATGCTCCTTATCAATCTACAGCCAAAAGCATCACTGGTTG GGCAGTCAAAACGACTCCTGCCAATGCAACGGGCGTATTCACAAACGCTA ACCAAACGGTCACTTATGTGTACGAAAAAGCGGACGGCGCTCCTGTTACC GTGAAATATGTCGACGTGGATGGCAACGAATTAGCTACTCCAGATACATT GAACGGTAAGCTAGATACATCTTACGCGGCAACAGCTAAAAACTTGAGTG GTTGGAAGCTAACAGCCACACCAGCCAACGCTAATGGCGTATTTACAACT GATGCTCAAACAGTCACCTTTGTATATGCTAAACAAGAAGACAATCCTAA AAAAGAGGATAAAAACAAAACACCTATTAAAATCAGCGAAAACAAACCAA CAGCAAGCAAAGTAACTAGAATCAAAAAACAAACAAAATTACCGAAAACT GGTGATAATCAACAAGATAGTATATTGTTTGGATTAATTGGTACATGTTT CGTTCTCTTAGGAATTTACTCTATCTCTAAGAAAAACAGCTAA ORF1590 (SEQ ID NO:24) TATTATAAAGGAGATAAGTTAATGAAAAGAAAAAAAACAGCATTACGTAT CTTGGTAACTCTGGCTGTAGTAATGGCAATTAGCTTTTGGGTAGGGACTA GCTCAAAAGAGGAAGTACAGGCGGCAGTAATTGATCAACCGACGCCAATT AATGAAATTTTTACAGATGAGAATTTAGCAAACGCAATAAAAGCAACTTT AAATAAACCTAGTACTACATCTGACGTTTCACAAGCAGAGCTAGATTCTA TAAGTGAAGTAACGGCAGAAAGTAGCAATATAGCTTCTTTAGAGGGGGCG CAGTATTTAAATAATATAGATACATTAATTTTAAATAATAATAAAATAAC GGATTTAAATTCACTTGCAGGACTATCTAAATTAAGGATATTAGAAGCAA ATGACAATCAATTAAGCGATATAAGTGCACTAGCAAATGTGACAAGTCTG CACCAATTAAGATTAGCTGGAAATCAAATAAAACAGTTAAATGGAGTTAG TAATTTAATCAATCTAGAAACCATAGAACTAAGCAACAATCAAATAACGG ATATAAGCCCAGTTTCAGGTTTGAAAAACTTAATTGGTCTTGGAATAGAT TATAATGATATCAGTGATTTAAGCCCAATTGCTGGCTTAGCAAAGTTAAG TCATTTAACTGCAGACAATAACCAAATAAGTGATTTGAGTCCTATTTCAA GCTTAGGGGCTATGGAAATTATGCGACTAGATAAAAATCAAATCAGTGAT GTAACCCCAATTGCGAATTTGGCTAATTTAAGCTATGTATTTTTAGCTGA AAATCAAATCAGTGATATTAGTTCTTTACAACCACTTTTTAATTCACCTA ATTTTTTTGGTATTACTTTAGACAATCAAAAAATAACGAGTGAACCAGTA TTGTACCAACAAGAGCTTGTGGTCCCTAATAACATTAAGGATGAAATGGG AGCGTTAATCTCACCAGATACAATTAGCGATAATGGTGTTTATGCAAGCC CGAATATTAAGTGGAACTTGGCTAATTATACTAACCAAGTAAGTTACACA TTTAATAAACAATTAGCACAGGGTTCTTTTAGCGGAACAGTGACCCAACC ACTTCACAATGCTTATACAGCGACATTTGACGTAGATGGAGTGAAAACAA ATGAAGTAGTGGAAGAAACGAAATTGCTTCAAGAACCAACAGCTCCAACG AAAGAAGGATACACTTTCACAGGCTGGTATGATGCGAAAACTGGCGGGAA TAAATGGGATTTTGCGACAGACAAAATGCCAGCAGAAGACATCACATTAT ACGCGCAGTTCACGATTAATAGCTATACAGCCACATTCGACATCGATGGG AAATTAACGACGCAAAAAGTCACTTATCAAAGCTTGCTAGAAGAACCAGC AGCGCCAACGAAGGATGGCTATACGTTCAAAGGTTGGTATGATGCTAAAA CAGGTGGAACTAAATGGGATTTTGCGACAGGAAAAATGCCGGCGGGAAAT ATAACGCTATACGCCCAGTTTACTAAAAATGCCACCCCAGATTCCAATGA CCCAACAACGGTTACCCCAACAGGAAATGGCAATGGGACAAGTACCCCAA GCAATTCAGGTGGAAATACCACGCTTCCGACAGCTGGGGACGAAAATACC ATGCTTCCAATTTTTGTAGGAGTTTTCTTGTTAGGAACAGCAACGCTTAT TCTCCGCAAAACAATCAAAGTAAAATAA ORF1654 (SEQ ID NO:25) GTGCATGTAGTACCTATCGCGAATGCGTGGAATTATTACAAACTATATAT AATAACAACGAGTAAGTTTGAAGGAGTGAGAGGTATGAAAAAACAAATTA TTACTATTGCTGGCGGAGGAAGTACTTATACACCGGGAATCATTCAAGCT GTACTTAACGGGCAAGAACGATTACCAGTAAGTGAAATCCGTTTGTATGA TATTGAAGCAACAAGAAATGAAAATATGTATTTAATTCTGGATTATATGC TAGAACAACAAGGCTTTTCATCAATTAAATTAGTACAAACAACCAATCCT GAAGAAGCATTTACTGGGGCAGACTTTATCTTTTCGCAAATTCGCGTTGG CGGACTTAAAATGCGCGATAAAGATGAAAAAATCCCACTAAAGCATGGAT TAGTCGGACAAGAAACATGTGGACTTGGCGGATTTTCTTACGGTTTACGT AGTATTGGCCCACTGTTAGAATTAGTTGGCTTTATTCAAAAATATGCGCC AGAAGCTTGGATTTTAAATTATACGAACCCAGAAACGATTATTTCTGAAG CTGTACGAAGACAATTTCCTGGTATTCGAATGATTAATGTATGTGATATG ACAATCGGAATTGAAGATACACTAGCTAAAAATTATGGCTATGACCGTGA TAATTGGATTGCTACTTACTATGGTTTAAATCACTTTGGTTGGTATACGA AAATTTATGATAAGTCATTAAAACGTGATATTATGCCAGAGCTTTTAGAG AAGTTGAAAGTCCAAGAAATCAAAGAAGAAGACCCAAGTTGGAATCGCGC ATTCAATATGATACGCTTTATGGTTCAAAATTTTCCGGATAACTTGCCAA ACAACTATTTAGAGTATTATTTGTATCCAGATATGTATGTCGATTACGCT GATCCAAATTATACCCGCGCGAATACAGTAATGGATGGTCGTGAGCAAAA AACACAAGAAATGGCAGATAAAATCCGCAACAAAGAAAAAGGAGATGTGC TTGATTTCTACTTTGGTGTACACGGCTTATATATTGTAGACATAGCTACT TCGCTACTAAATGATGAGAAAAGTCGCTTTATGTTAATCGTTGAAAACAA AGGATCCATCCCGAATTTACGTAGTGATGCAGTTGTTGAAGTTCCAGCAT ACGTTGGTGCGACAGGTGTAGAAGCAATTGCCTTGCCTGCAATTGGTGAT TTCCATAAAGGTATGATGGAAGCGCAAGTTGCTGCGGAGAAACTACTCGT AGATGCGTACTTTGAAAAATCTTATCAAAAAGCATTACAAGCATTTACAT TAAATCAATCGGTTCCAAATGCCACAGTGGCGAAGAAAGTATTGGATGAA ATGATGATTGAAAATAAAGCATTTTGGCCAGAATTAAAATAA ORF1655 (SEQ ID NO:26) TTAAAAATGCTAAATCAACGTCAAAAAAACATTTTAAGCACACTGTATAA TGAAAATAATTGGCTACTTGGGAAAAAATTAGCAGATTTATTCCAAATAA GTGATCGAACTATTAGAAATGATATACGTGTTATTAAAGAGAGCATAGGC GACGATTTTATCTTTACTTCTAAAAAGTTAGGATACGCCTATAATATGGA AAAACCTTTTCCGATTGACGTTGAGGCAGAAACTGGATTTGAACAAAATC GGATGGCGCAATTAATTCAGCAATTACTTGTCGAAGAAGGCGTAGATATT TACGAATATGGTGCCGAAACATTCACTTCAGAATCAACCATTCAACGCGA TATTCAGTGGTTACGAGGCTACTTTGAACAACTTTTAGGTTTAGATGTAG TAATTCATTCTAGTGATGGTGTATATGCCATAAGCGCTTCCCCCACAACG AAAATGGAGCTATTAAATCGCATTGCAACGTTGGATGAAGGATTAAAGAC CAATTTATTAACAAATTGTTTTCCAGAAATTAATCATGAAAAAATTCGCC AAATATTATTAGAAATGATTCATCAACATAAAATTGTTTTAAAGTATTTT GATGAAACTATTTTGCTTGCACAACTTATTTATGGAAGTGCCTTTTTTCA AAAACATGCGGAACAACAAACTTCTACGAAAATTGCTAATCCATTTCTTA AACAACTTTTTGATACAATTCAACAAGAAATGGGTTACCAGATTTCGGCG GAGATGAAGCAATTTATAGTATCAGAATATGAAAAAATTGTTGCAATGAA TCATTTTGAAAACCAAGTAACGACAAAAATGGTTTTAGAAGGCGAACTTT ATCAAGAAATATTATTGATTTTGGAAGAAATTAAGCATGTATATTTGATT GATTTTACGGCAGATTTAGACGTTACAAGTGATATGACGAAACATATTTT TATTGCGCTGGAACGTGCCAAACGCGGAATTGTCATTAAAAATCAAGTGA CGCATATCATTACGCAGCAGTATAGCTACTTACTGGATATCGCGATTTTC ATTGGAGAAAAATTACTTGAACGTCTAGGTGTAATTTTAAATCAAGAAGA AATTATTTTATTGGTTATGTATTTATACCAATACTACCGAAAAATCGAAG CGAAGCACCAATTAAATCAAGTAGTGCGCATAGCTTTAATTGTTTTAGAA GGTAAGGCTGCGATGTATTACTTGCGTGAACAATTAGCCGAAGTATTACG ACCAGTAAACGCTGAAGTTATAGAAATAACCGATAATTCCCAGTGCCAAT TACTGTTAGCTGAAAATATCGATGTTGATTTATGTATTTCTACTAAAAAA ATTGATTTGCCTGCGGAAGTTCCGTGTATTATTTTGGCTAATAACATCGG TTTGATTGAAGAAGTAACAATAAAAAAACAACTTTCAGCCACAGTAGAAG CAAATAAAATGAAAAAATTTGCTTATATTAAAGAAAAATATTTACACGAA GAGCTTTTCTTAACGGATTATGCGTATGAGCAAAAATATAATGCGATCGA ATTTTTAAGTCAATATTGCATTGATAAAGAATATGTTCCAGAGCGGTTTA CTGAGAAATTATATAATCGTGAACAACTATTTTCAACAGCGATTCCGACT GGGATTGCCTTACCCCATCCAATTAAAAATGTGGCGCGCAAAAGTGGTAT TTTCATTTGCATTTTGAAAAAACCGTGTGCTTGGGATACACATAAAGTTA GTTTGATTATGATTCCAATGATTGAAGAATTGGACGGGACAGAGGCACCT TTAATTAATGATTTTTTATCACTAATAGCTTCTAATAAGTCCTATGTAGA GCAAATAAGTGCATGTAGTACCTATCGCGAATGCGTGGAATTATTACAAA CTATATATAATAACAACGAGTAA ORF1680 (SEQ ID NO:27) ATGGAACAAATTATGACTCTTTTACAGAGTATAAAGTTAGCGCTAAAACA ATTATTGTCCACCAAATTTCGAACATTTTTAACAATGCTTGGAATTATTA TTGGTGTTTTTTCTGTTATATTACTTGTTTCGATTGGGGAAGCTATATCG AAAAATGTCTCCACACAATTAGGTGATATGGGAAGTAATCTTTTGACTGT TAATTTTTATTCAGATAATCCAAACGATAAATTCACATACAAAGATGCAA AAAAACTTTTGAATGAAGATGAAATTGGTTCGCCGGAAGTGATGCAGACA AAGGAAGTTAGAACAAGTGAAAAGACAGCTAGTAATCAAGTAGCGGGAAT AAATGAATATTATGCGAGCATAAAAAATTTGGAATTAGCATCAGGCCGTT TTTGCTCGAATGTAGATGTTATCTATGCCCAAAAAGTGACAATTATTGGC TCAGAAATTGCAAAAACTTATTTTAAAGAACAGAATCCGATAGGTGAATA TTTGCAAATTGCAGGTGCTAGGTACATGGTCATTGGAGTTTTAAAGGAAA AGGGGGAGAGTTTATTTGGATCGGCAGACAAAAAACTTTTTATCCCAATT TCTTCCGCAGAACGACTTTTTAAAACAGATACTGTGGATTTGTATTATAT TCAAACAAAAAAAGTAGAACAAGTTCCAGCAGCAGTTAAGGTAGTAAAGA AAAAAATGCGCCAGTTTTTTCCGAATAATGAAGATGCGTATACGGTTGTA AACCAGCAACAGGCGTTAGATACGTTTGATAGTATTACGGGAACACTCAC GATTGGACTAGGTGCGATTGCAGGGATTTCGCTACTCGTTGGCGGTATTG GTATTATGAATATTATGCTCGTGTCTGTCTCAGAACGAACCCGAGAAATT GGAATTAGAAAAGCGATTGGCGCAAGTAGTGGCAATATTTTAATGCAGTT TTTGATTGAAGCAGTTGTGCTTAGTTTAGTAGGCGGTTGTATCGGGATTT TACTAGGAATTTTTTCCGCGCAAATAGTTACAACTACATCAAGTTTTGAA ATGTATGTTTCTGCTTCTACGATTCTTTTAGCGGTTGGTTTTTCGATGTG TATTGGGATTGTATTTGGTGTAATTCCCGCACAGAAAGCTTCAAAAAAAA AGCCGATAGATGCGTTACGGGCAGATTAA ORF1681 (SEQ ID NO:28) TACGAAATCTATTCAAGTAGTAAAAGGTCTTACAGAGAAACAACTTGTGA TTATTCCATAGACGGAGGTGAGCAAGACTTGATACAACTATTTAATATTT CCAAATCCTATCAAATGGGTGAATGCACCATAAAGGCTCTAGATAATGTA TCATTGCAAATTGATCAAGGGGAATTTCTGGCCATTATCGGACCGTCTGG CTCTGGAAAATCTACTTTAATGAACATCCTCGGTATACTTGACAGAGCAA CGATAGGAGAATACTACCTCAATAAAACGAATTTAATGCGAATATCAGAT AAGAAAATTTCTCGAATAAGGAATAGGAAAATTGGTTTTATTTTTCAACA ATTTAATTTAATGCCACGACTTACTGCTTTTGAAAATGTAGAATTGCCAT TAGTATATCGAGGTGTGGGCAAAGCTACTCGAAAAAAAGTAGTATTAAAA AGTTTAGAACGTGTCGGACTATTAGATAAAGAAAAACATATACCAGCCCA GCTTTCAGGAGGACAGCAGCAACGGATTGCAATAGCTCGAGCCATCGCTG GAAGTCCAGAATTAATATTAGCAGATGAACCTACTGGCGCGCTAGACTCT AAAACTGGAGAAGAAGTAATGACTTTGCTAAGAGAAATTCATAGAGAAGG AAATACATTAATCATGATTACCCACGACAAAGAAATTGCAAATCAAGCAG AACGAATAATAGAAATAAAAGACGGAAAACTCCGTGAATGGAACAAATTA TGA ORF1683 (SEQ ID NO:29) ATATTGAAAAAAATAAGCTGGGTGATTATCATGCTGGTTATCGTTGCTGC ATCGGTTGGCTATTATTTTATAAAAGAAAATGAGCGAAAGACGCCACAAA CAATTGATTACAAAACAGTTGAAACAAAAAGAACAGATTTAAGTGTATAT GTTTCCGCAGAAGGTCACATTGTAAAAAAAGTAAATGAATGGCCAGATTA TGAAGATTTTGCTGTCAAAATTATGGTAGATGAGCTAGAAATTAACCAAA TAAAAGAAAAACAGACAGCTGATGTGTATGTCGAAGCAGTAAATAATAAA GTATACAAAGGAAAAGTTGTAGATATAAATGAGAAGGGCATTATAAACGG GTCAGTAACTTCTTATGCCGTGACGATTGATTTAGAGGATGAGACGAAAG TAAAAGAAAATATGTCTGTAAGTGCTGATGTACTTGTGGCTCTAGAAAAA AAGATTTTAACAATTCCAATAGAAGCTGTTAATACGGATAAAGCTGATAA ACATTATGTCTATACAGTTGATGCAAATAAACAAAAGAAGAAAATTTGGA TTGAAGTAGGCAAACATAATACGAAATCTATTCAAGTAGTAAAAGGTCTT ACAGAGAAACAACTTGTGATTATTCCATAG ORF1684 (SEQ ID NO:30) ATGGTAAAATGGCATTCTAAAGCTGTTTTTAAACAGCTTTATAGAGAGAG AGGGGAATCATTTATGCCAAAAATTGCTAAAGGTAATCGACTCGAGAATG TTGCTTTTGAGTACATTAAGAACAAAATCACAACTGGGGAGTATCCAACG GGTTATCGTGTTGTAGAAGCAAAGTTATCTCAAGAACTAAATATGAGTAG GACACCAATTAGGCGAGCGATTATCAACCTTTGCCATTCTGGATTTTTAG TCCACCAATATAATCGGGGTGCTTTTGTTCAAAACACTGAAGTAACTATT ACAGAATTTTTTTCGCGAATGAAATTAGTCGAACTATTGATGTATGAAAG TACAGAAAAATTAATTCTACGTGAAGATTATATTGTAGTGGACGATATAA TAGAAATAGCAGAGAAAGTAATTCAATATGAAAAAAACAAAGAATATGAA TTAATGCGCGATACGTTTGAAGATTTTATCGTCGCATTTATAGGTAAGCT AAATAATGATTATTTTAATAGAATAATTCAAGAATTATGGAATGGAATCA ATGATAATGCAACAAAAGAAGTAAGACTAATTATTGTTTCGGCAAGTGAT CGAATTGCGGAAGAATTAGCTAATATAATTGAAATTTTAAAATCATGGAA TTACGGGGAACTAAAAAAATGTTTTCAACACATAATGAACGCAATGATTT TGATTGCTTTTTAA ORF1717 (SEQ ID NO:31) AAATTAACTACGAAAGAAGGAGGGGAGCTGATGAAGAAGTTTTCCATGCG AGTGGTGCTTATTATTTCTGTGCTTTTTATTGCACTGGGGAACGCTAATG TTTCTATCGCACAAGAAAGGGACACAACGAATAAGCTTCCAGAAGAGGAG CTGGGTTCTCTGGATACCTCTAATCTTATTGCAGAAGAAGTCGCACAAGA CAAACCAGCAGAGGTCGAGAACTTAGAAGAAATTCCAACTACGGATGAGT TGATGCAAAATCCAGATGTTCGAGAGCAGTCTGTTGCCGATTCGGATGAT CCGGATTTAACAGCGGTAAGCTCGGGTGATTACTGGACGATTTATTATAA TTCTGCGAACGATGAATATAGCTTGCGTATGTTTGGCAACGTACCAAGCA GTAAACCGAGCGCTTGGAATAGTTATTTGAAATACATTAAACATATAGAG ATTGAAGAAGCTACTTTAACAGGGGATTTTTCATCGTATTTTAGAAGTAA TGTTTTCACAGTACTTGAGAGTGTGAGGATTGAACGTTCAAATTTGTCTG GAGTGACGTCTTTTGCAAGGGCATTTGAAGGTGACAGTGAATCAGAATCA CCACTTGAAAAAGTGATTATCAGAGATAATTATTATCCGGAGACGCCTTC TTTAACAAATATAAGTAGAATGTTTACCTTATGTCGTAAACTTAGTGAGC TTGATGTGAGTGGACTCAATACAAGTTCCGTCACTAAAATGGATACCATA TTTAGTAACGCGAATAGCCTTAAAGAACTGGATGTAAGTCATTTTGATAC GAGTTCAGTGACTGATATGAGCTCCATGTTTGCTGCTTGTAATAGTCTTG AAGAGCTTGATGTAAGTAATTTTGATACGAGTTCCGTTACTAATATGAAG TATATGTTGAGTGGACTCCACTTGAAAAAACTAGATGTAAGCAACTTTGA TACAAGTTCCGTTACCAATATGTATGGCATGTTTGCTTATTGTTACAATC TTGAAGAGTTAGATGTAAGCAACTTTGATACAAGTTCCGTGAATAATATG CTGCATATGTTTTATGTTTGTAATAATCTTGAAGAGCTAGATTTAAGTAA CTTTGACACCAGTTCCGTTACTAATATGTTTGCCATGTTTGCTTATTGTA CTAGTCTTAAAGAAATAGATGTAAGTAATTTTGATACGAGTTCTGTAACT ACTATGAGTGCCATGTTTTTTGAGTGCAGCTCACTTGAAGCGCTAGATTT AAGTAACTTTGATACTAGTTCCGTGACTACTATGGCTTCCATGTTTGAAA ATTCTACAGCGTTAAAATCTTTATATTTAGATAATTTTACAGACGCAGCA AGCATGACAGATATGTTTAAGGGAACCACCTCTTTAACCTACTTATTTGT CAGTCACAATTTAAGTACTTTTAATAGGTTAGAAAATACAAGCTGGTATG ATGAAAAGAATTGGGTGCAGTTTTCGAATCTCTCGCAACTACAGACATAT CACCGGAAACAAAGTGAACCTACTGGCTATAGAAAAGGCGCTTTCCTTTC TCTAACAATGGATGCGATGGGTGGAGAATTTGAAGATGCGGAAGAACAAA AAGTACAAAATAAAGTTTCTGGGGAATACTGGGAAGAGATAGTTCCTGTA AAAGAAGATTATTACTTTGACGGGTGGTATCTTGATCAAAACTTCACTAA TAAGTTTGATTTTTCATTGCCTGCTGCTGTATCTACAACTATCTACGCCA AATGGGTAGAAAACTACACGGTGATTATTCCAGCTTCTATTTCCTTAAAT GAAGCTACTGAATTGAAGGTAGAAGGGATTAATCGAGGGAGTAAAGCTTT GTCCGTGGGATTAAACCGATTAGCAACGTCTGTTTCTGAGAGCAACGAGC TAACTTTAGCTAATACGGCAGACACGACAGTCCAATGTTCGGCACCGCTG AGTTGGGACGGTTCCGAAAACAATCCAGAAAAAGCGATTTTAACCCTAGC TCCAGGTTCGGAAATAACAGAAGGCGATGCAGTCATGGCTATTGAAGCGC CAGAAAATATCCAGGCTGGAAAATATACAGGGAATCTAGTATTTTCGATT AATTATGAATAA ORF1718 (SEQ ID NO:32) CATTCAAAGGAAGTGTTTTTAATGAGAGAATATTTAGATTCAAAAAGCCA AAAAAAGGTAGCGCTTCTTGAGAAGATTTTTTATGCGGAAAATCATACAA GTACACAAGAGGAACTATTAAATGATTTGAACATTACGTATCCAACCCTC ATTTCTACGATTAAAACAATTAATTTTGATATTGAACGATTTGGATACAA AGCGTTTTCGATTGTTCACTCCGCGCCAAATTTGTCCTATACCTTAAAAA TATCGGATAATTGTAGTATTCAACTCATTATCAACGCCTATATTAGAGAA TCGCCCAAATTTCAAATTCTCGAAACTTTATTGCTGGCTTCCTTCCCTAA TCTACAAGCATTGGCAAAAAAAGTACATGTTTCTTATTCTGGGATAAAGA AAGAAATAAAAGAATTGAATGAAGAGCTAAGTGAACGGAACTTGTATATT TCTACAGGAAATCAGGTAGAAATAACGGGGGATGAATTTTCATTAAGAAT ATTCTATGCCTTCCTTTTTTTAGTCGCATATAGCGGGGATCGTTGGCCAT TTTCTTTTGTTCGATATGATGAAATCACTGACTTATTAGAGAGTTGTCCA AAAGAAATTTATAGAGCAAACTCGATAGATAAGGCGATGATGATTCATTA TTATGTCGCTATGCATTTATTAAGAGATCGAATGAATTGTCAAATTGATA CAACTAGGCAGTTTAAAGTGGCCCTATATAAGGCTTGCACCGAGGAGTCT AAGAAATCAGAAAGTGCGTTCATTAAAAAGGTAGCGAAACAACTTCCTAA TAGGAACTATAAAGAAATGACCTACACGACGCAAATTATACTGAGTACCA TTGTTGCTTTCGGCAGTTATTCTTCCATTGAAAAAATGCCTTCCTTTTTC TACATGGATGAACAGTTAGAAGAAATGGGCTTCATGAAACTAGTTGATTT TGCCAGTGAACGAGTAAATGATAATCTCTCTATTCCATTTTCAGAGAAAG AGATGGAATTGCTCCGTTACTCCTTTGCGAGTATAAATTATAGATATTTC TTACTTGATAATTTAATTAATAAGTTCAATAATATTGTGCCAGGGTATAC AGATCTTGATCGAAATATAAGAAAAATCCATAAAGTGAATCACCTAGAAC CATTGATTAGTCAATTAGTAAATTTAAAAGAAATGGATCCATTAAAACCG TTTGAAGAAAGACTTACTTCAGATTATCTGATCATTTTGGATAAACGGAT TGATTTTTCTATACACACCTTGCCTATTAAAGTAACTATTTTATCGACCA TATCTAATGAAACAGCCGTATTTGATTTTATGAGGTATTTTTCTAGTTAC TACAATCTGGAAATAATTAATCAAGTTGATCCGGTGGTGGATTTATATAT AAGTGATTTTTCCGTATCTCCCGAAGTATTGACCTCTTTACGTATCAATC AGCCAATAATCTATGTAAATACTAGATGGCTAGAATCTGATTATGTCAAA ATTAATGATAATCTGGCGAAAATAGCGAGAAAAAATTTATCGCTAATAAA AAAGATTAGGGAAACACTTGTTGGAATGGATATGGAAAATGTTTAA ORF1739 (SEQ ID NO:33) GAAGCAAGAAAATCGAATGTAAGTATTCGATGGTCATTTGCTAAATCCTT AACTTCCCAGCTTTTATATGGAGAGGGAAAAAGAATGAAATTTGCTATTA TAATGCCTTTTTACAATGCCGAAAAAAGGTTAGCACTATCCATAGATAGT ATAATTAAGCAGTCTTACAGCTTTTTGAAGCATGTGGAAGTACTGCTTAT TAATGATGGAAGCACGGATGGAAGTGGCGCTATCGCAAATCGTTACGCTA CAAAATATCCTAACAATATTCGCGTGTTGACCGTTCCAAATGGTGGACCG GCAAAAGCGCGTAATATCGGAATACATAATGTAAGTGAAGATACTGATTT TGTTGGTTTTTTAGACGCCGATGATATAATGTCAGAGAATATGTTAGCGA GTATAGTTACATTTCTAAATGAGTCTAACGTTTCTATGCTTGTGCCAGCT TTTTATTACTTAGATGATTTTGGAAGTAAGAAAAAAATTTCACCACATAA ATTAAATTACCGTTTTGCGAATGGAAATCGAGTTGCTGATATTGAAAAAG AACCGGAAGCAATTCATTTTTATATTGGCGGTACTTTTTTACGTTATGAT TGTTTGAAAGAATTTACTTTTGATGAGTCGCTTTATTTTGCGGAGGATCA GTTATTAATTACCCAGTTCTTACTGAAATATCGGAGCTATGGCTTGATTG CGGATGCGGGGTATTATTACTATCGTGATCTAAAGCAAAAAGGTTCTTTA GTAAGTTCGTCTTGGAAAAAACCAGAACGATACACGCCTTTTTTGCAGAA AGTATATCAAACCTATTTAACTGACTCGAAAGAAATATATGGCAAAGTGA TTCCCTATGTGAAGTATCTAATTGCGTACCATGCAAAATTGTTTTTTTAT AAAGAAAATACTTATTTCCGGGAAGTTTTAAGCGAGTCGGAGCAAGCGAT TTTCGTGCAAGAATTACAAAAGATTTTGCAGGAAGTCGGAGCAAGTACGA TTATGGAATTAGACACACCTCTCGTAGTAAAAGAAATGATGTGCTCGATT TTGCAAAATGGATGGCCGCTGCAATTTGAAACGGCTGAAAAACAAGATAT TCCACTTGTGACAGTAAAAGAAAATTATCGTATCGGCAAAACAGTCGCGA TTGAATTACTTCTAGAAGAAGCGGATATTCATGACGTGAAATGGGTTGCT CGCACGTCTTTTAAAGAAATGCCAGCTCGGTTAGTCAAACGAAAAGAGAA TCAAACTATTTGGGATGTCGTTGTCAGAGAAAAAGGCACAGTAGAAAAAG CTGTATTTAAATTAAAACCGTATCAAACGAAAGCGCGTCTTTTTTATCAA GATGAGGAAAAGGATACGCCTATCGCCGACATAAATATCATAAGTAGCAT CTTAGGGAAATTAAAACGAAATCGAGCGTTAAAGCGAAAGTTTAAACAGG GGGGAGTATCCTGA ORF1813 (SEQ ID NO:34) CCTCGGATGCAAAACGCCTTAGGAAAAGCGCTAAAAAACAACGAAACAAC ATTCAATTTTGACGAATATCAAAAAACGTACCGTGGTCAAATGTGGGTGC TAATGAAAAATGGTATAGTAGATGTTGAAGCAACGAACGCGTACAATGCC GCCGTGCTTAACGGGGAATTACCACATGAAAGCAATGAAGCGCAAGAAGA AGCCGAGTTGTTGCAGGCAGTTATTCAATCGGTGAAAGAAGGAATAGACC CGGTTACTGGGCAAGAGATAAGTAAAGCGCAAGGGTTTAGTATTATAAGT GGCTTTATCTTTTACTACACTTCTGGTGGGTATAAAGGAAAAAAATTGAA GATTCCTAAAAAATTATTAAACAATATTAAGAATAGGCGTTCGAAAGCAC CCAAACTATCTACTTTATCCGAAAAGGAACAATTGAAACTAGCAAATAAA TACAAGAAAAAAGCACCAATCGCAATTCCAGATAACGCTAAAATAAAAGC CCAGACAAAAAAAGCTGGCTATGAACAAATTACTTATAAATGGAATGATG GTCAATTTAAGTATGAAGTGCGATGGCATACAAGAACTCCAGAAGCACCT TTAGAGCAGGGGAATACATGGGTTGTCCAAAGAACAGTTCCTGGAAATGG AGGGGACAAGCCACAAACATTCTTCAAAATTGGTGATGATGAGTGGGTAG AAGGATATAAATGGTATGATGCTATAAACGCAAGAAAAGCAGGAAATGCT ACTCCAGAACAAATAAAAATTTTAGATAAAGGTCATTGGAAGGAATGA ORF1849 (SEQ ID NO:35) AATGAAAACAGCTCGGGGACGCCCTCAAGCTGTTTTTTTATGTTTCTGGT GATAAGAAAATGGGAACAAGATACTATTAAACTTTTTGTCAGGGGGAGCA AGATGAAATCCAAAGGGAGACTGTTTTTGTACGTTGTTTTGGCGTTGTCG ATTGTTATTGGGACGAATGTATTTATAAAAATAGACGCACATGCAGCCGC TGCACCACCAGCTGCAATCAGCCAGATTTTTCCCGATGATGCTTTAGCGA CAGAAATTCAAACTACACTCGGAAAGTCTAGTACAGCAGAGGTTGTCACT CAAACAGATTTAGATACTATTAATTCATTAACCCTTACTTCTAAAGGTAT CAGCTCCCTAGAAGGTATGAACTACTTGACCAATTTAGGAACTTTAATTT TAACTGGTAATCAAGTAAGCGATATTTCGCCACTTAAAGGCTTAACTAAC TTGACCATGCTTCAGCTGAGTGGAAATCCGATTAGCGACATTAGCGCACT TAGTAACTTGAAAAACTTACAAGCTCTAGATATTAACGACGCGCAAGTTA CTGACATCACGCCACTGAGCGGTTTAACAAATCTAAAGGGTTTAGGCTTA TATAATAATCAATTGGAGAACCTTAGTGGAGTAAATAGTTTACATCAACT CCGCTCCTTAAATGTTAGTAATAATAAGCTTACGAACCTAGATGAGCTAC AAGCGCTAAGCAATTTAAGCGTTCTATATGCAAATGAAAACCAAATTAAC AATCTTCAGGGGCTAAGTAATTTAAATAACCTTTTCTTGCTTGATTTATC AGCGAACCAAATTGTGGATACTACTCCACTCGCTGGCTTAACTAAGGTAC AAACATTATACGTATCAAACAATCAAATTAGTGATGTAACTGGTCTTTCG AGTTTAATAAATCTAGATTGGCTCGATATAAGTCAAAATAAAATTAGTAA CATTAGACCTTTAAACAGTTTAACGAAGCTAACAATTATTCAAATGACTA ATCAATTAATCGTAAACGAACCGATAAGTTTCGAAAGCACTGTAACGATT CCTAATTTAATAAAAAACATTGCGGAACAAACGATTGATCCCGATACAAT TAGCGATAACGGTGTGTATGCGAATGAAGCTGTTACATGGAATTTACCTA CTTATATTCCTAAAGTCAGCTATACCTTTATTGAACGTGATACGATTGGT AATGCAACTGGAAATTTCAGTGGGACTGTAGAACAGCCATTAGTACAATA TTTTAAAGCAACTTTCAATATTGACGGGCAAGAAACAACGGAAAATGTCG AAACAGGGACACTTTTACAAGAACCACCAACCCCAGTCAAAGAGGGTTAT ACATTTAACGGATGGTATGATGCTGAAACAGGTGGAACAAAATGGGACTT TACAGCCGATACGATGCCAGCAAATGATATAACGTTGTATGCCCAGTTTA GTATTAATAGTTATACCGCAACTTTTGATGTAGATGGCGTCATTTCTACT CAAGCGGTAGAGTATCAAGGTTTACTGGAAGAGCCACCAGCGCCAACTAA GGATGGTTATACATTTAAAGGTTGGTATGATGCCAAAACTGGTGGAACAA AATGGGACTTCACAAACAATCAAATGCCAGCAAATGATATAACCTTGTAT GCCCAGTTTAGTAAAGATGCATCTTCTGGTGGGGACGGTGGAGGAACCGA TGAAGGTGGAGGTAACTCTGAAAATAGTACAGAGGGAGCTCCTAATACGA GTGATATAGATACTATAAACCACATCGTACTACCAGCAACAGGAGATGAC CATGTGCTTTTTCCAATCTTTATTGGAACATTTCTTACGAGTTTAGCATT ACTTACACTTAGAAGAAAATAA ORF1912 (SEQ ID NO:36) AGCAGAAATGCACGATATAGAGACCAAACAAGCCTCCTTGCGAAAGGAGT GGAACCAATGAGTCGAATCGACATTGCAGAACTCAATGGCTTTCTTCAAG GATTACGAAGCAGTAATGCTGAGGCTAAAAAGATGATACGCGGAATTCAA CAAGCAGCAAGCAAGTATGCGCAAGATAAAAGTTTAAAAGGGCAAGCAGT ATCAGCTTCCCAAAGCTATTTTGCTTCCAGTTATCCCTCTATTGCACAAA GTATTTTAGAAGCTCTAGAAGAAAGTGAAGAACGTCTAGCACAATACATA CGCGAGTTTGGTAGCCAAGTCGACAGCTCGCCTTCCGCACGAATTGATGC GGAAATCCTTCAAGAAGCGATGGCGAAAGTGGCGAGTTTGAAGCGAAAAG AAGAAGATTTACATCGCCAACTCACTGCACCGAATACGAAACCGGATATG CAACAAGTCTACGTAGTCCAAGCAAGAAGTGCGCACACGCAATTACTGCA AGCTATCGAAAAAGAAGATATACTAGAGAGGTACATCGCCTTTGAACAAA GTCACGCCCAGTTTTTTAGTGCGTTAACCGAACTCATTCACTCCACAGGA CGAGCGGTGCAAGAGTTGAAACAAAATGTGACCTTCCATGAGAAAACAGG CACCTATGCTGTACCTAAAAGCGTTCATGCATCGATTAGTTTGATGAGAA AAGCGATGGATAAAGCACGCAAAGAAAACGCCAAAGATTCCTTCCCAGAA GCATTCGAAGACTATCAGTTATTCGCCTATACTTATGTGAATGACAAAGG CGAAACCGTCACGATGTGGCTATTGGAACGGAATGGCAAACGTGCCAGTA ATAAAGAACTCCAAGCTTTTCTAGAGGAGAACGGAGCCGAGTTAGACCCT ATTCTGTACACAAATCTTTCCGGTGATGAACTAGAGCGCAAAGTAAATGA TGCATGGAAAGACGGCGTCAACTACTTAAATGGTCAAAAAGTAACCGGGT TTTCCGAGGCGACACTGAGGTCCTCTGCTTACGTAGCTAGCGTGAAGGAT GCGATGGATGACGCTGGACTAACCGATATGGCATTAGGATTAGGCTTTGG TATTGCGGCGGCGAGGAATAAAAAAATAATAGCTAAGAAATCAGAAAAAG TAGAAGTTGATCTTGGAAGATATTCTGTAGCAACCTTAAATAGAGATCAA GCACGATTAGTGGTTGAACATCTTTTAGAAAGAGGAGAAATAAGCTTAAA AGATTTGGGTGATATAATACCAAAAGGAACACCAAACACTTTTAAAACTA CAGATACCTTGAAGAATGGTGCTAAGTATGAATTTCAATTAGCTGATGGA CAAAAAGCGATAATTAGGTGGCATGAACCAGACCCTATTGCAGCTGCTAA ATTTCCTGGTTCAGCTTCTGGTTCAAGATGGACTGCTCAAATTAAGATAG GAAGTAAACAAGTAACAATAAATAAAGGATGGACAAAAAAGCAAAACTCA AATGAAGTGCATATTCCAATAAAAGGAAGGTAA ORF1913 (SEQ ID NO:37) ATGGACAGCACGCACACCCGGTTAGAACAGCAACTACAACAAGTGAAAAA AGCGCAGGATGTTTTACAAGATAATCTGGGGCAGACTAAGCGCAAACAAG TGGAACAAGAATGGTTAGAAGAAGATAGTCACCAATTAGAAATGGAGAAA CAAGGATTATTGGACTTCTTGCGAGGCGGTTGGCAAGGGGAGGAAGCGAA TGGTTTCCACCGCTATCTAGAAGAACAACAACACGAAGAAGCGATGGCAT GGCGAAAAGATTTGTCGGAAAAACGTGTTCATTTGGAAGAAGAAGCGCGG ACTACTAGAGCAGAAATGCACGATATAGAGACCAAACAAGCCTCCTTGCG AAAGGAGTGGAACCAATGA ORF1998 (SEQ ID NO:38) GGCGGTATTTCGATGAAAAAATTAGAAAAAAGCGTACCAGTAATCCGGTT TAAAGGCTTTTCTGAAGCTTGGGAACAGCGTAAGTTAGGTGAAATTGCGA ATTCCTTCGAATATGGGCTTAATGCAAGTTCTAAAACATATGATGGAGAA AATAAATATATTCGAATTACAGATATTGATGAAAGTTCTCATGTATTTAA TCAAGATAATCTAACCTCCCCAGATATAAGTTTAGATAACCTAAATCATT ACTTATTAGAAGAGGGTGATATTCTCTTAGCGAGAACAGGAGCAAGTACT GGAAAATCTTATTGTTACAATAAAATAGATGGCAAAGTATTTTTTGCTGG GTTTCTAATAAGAGCAAAAATCAAACATGAATATAATGTCAGTTTTATCT TTCAAAGCACTTTAACAGAAAGGTATAATAATTTTATTCAGGTTACTTCT CAGAGATCAGGCCAACCAGGAATTAATGCTCAAGAGTATGCTAGATTTGC TTTATATATTCCTAAATTAAAAGAACAACAAAAAATAGGTGACTTTTTCA AACAACTAGACGACACTATCGCTCTTCATCAGCGTAAGTTAGATACTTTG AAACAGATGAAGAAAGGACTCTTACAGCAAATGTTCCCTAAAAGCGAAGA GGATGTCCCAAAGATTCGTTTTGCTGATTTTGACGAAGAATGGTACCAGC GTAAGTTGGGAGAGATTTCAGATAAAGTTATCGAAAAAAATAAAGAAAGT ACATATTTTGAGACTTTAACCAATTCTGCCGAGTATGGAATTATAAGTCA ACGTGAGTTTTTTAATAAAGATATCTCTAATGAAAAAAATTTAAATGGAT ATTATATTGTCCGCGAGAATGATTTTGTTTATAATCCTCGTATTTCGAAT TATGCACCTGTGGGGCCAATTAAGCGTAATAAACTAGGAAGAATTGGTAT AGTCTCTCCTTTGTATTATGTTTTCAGAACATTTGATACAAACCAAAGCT TCTTGGAATATTACTTTGATGGGACAGTTTGGCATAATTTTATGCTATTG AATGGTGATTCTGGGGCAAGAGCAGACCGATTTGCAATCAAAGATTCAGT TTTAAAAGAAATGCCTATTCCATATTCAACTTTATATGAACAAGAAAAAA TAAGTTTTTTTTTAGATGAGATAACTATCATTATAAATCTTCATCAAAAT AAACTAAAGAAACTCTCTTCTCTAAAAAAAGCCTATTTACAAAATATGTT TATATAA ORF1999 (SEQ ID NO:39) GAGAAAGAAGGAAAAAACATAATGGCATTATCAACTGAACAAAAAACAAA AATGTGGGCAATGCTCAACCAAACACGCGGTCAAATTGGTTTAACTGCGT ATAAAGACTATATCTTTGGAATTTTGTTTTATAAATACTTATCTGAAAAA GCAACACATTGGCTAAACGGCGTATTACGCGGGGAAAATTGGGAGAGTGT TTATTCTCAAGATTCTGTAAAGGCCTTAAATTATATGAAAAAGAATCTTG GATATGCGATTCAACCAAATGAATTCTTTGTAGACTGGAAAAAAGCAATT GATACGGACCGTTTCAATATTGGGATGATGACAGATACATTTACGCATTT TAATCAACAAATTGCATTTGAAGCGAAAAATGATTTTGAAGGAATTTTTG ATGGTATGCGCTTTGATAGTGCGGATTTAGGTGCTAATGCACAAGCTAGG GCTAGTGTCATGATTTCTATGATTGAATTGCTATCCTCTCCTGAATTTGA TTTATCTGGTAGTAATGATACTGTTTCAGATATTTATGAGTATCTAGTTG CACAATTTGCTACTGTCCTAGCATCTGATATGGGACAATACTATACACCA AAAGAAATATCTAATGTAATGGCTCGGATTTTAACTTTTGGCCGAGAAGA TATGGAAAAATTTTCTATCTTTGATCCTACTGTTGGTTCTGGTTCACTTT TACTTACAACCGCTAGTTATATGAAGAACTCAGGTAGACGCGGGGTGATT AAGTATTATGGTCAAGAAAAAGATGCAACACCTTACCGTTTATCAAGAAT GAATTTGATGATGCACGGTATTGAATATAATGATATTAATATTAATCATG CGGATACACTTGAAAGCGATTGGCCAGATGGGGTAGTGGATGGAAAAGAT ACTCCTCGAATGTTTGATGCAGTAATGGCGAATCCTCCTTATTCAGCACA TTGGAATAATAAAGATCGTGAAGATGACCCAAGATGGCGGGAATATGGTG TTTCACCTAAGACAAAAGCTGATTATGCCTTTTTATTACACTGTTTGTAT CACTTAGAAGATAATGGACGCATGGCGATTATTTTACCACATGGTGTATT ATTCCGCGGAGCTTCTGAGGGGCGTATCCGAAAAGCTTTAATTGATAAGC ACCAGATTGAGGCAATAATTGGTTTTCCTGAAAAATTATTCTTAAATACA CCAATACCTGTTTGTGTAGTTATTTTAAGAAAGAATCGTATTGAATCAGA TGTTCTGTTTGTTGATGCGAGCAAAGGATTTGAGAAAATTAAGAAACAAA ATAATTTACGTTCTGAAGATGTGGAAAAGATTGTTGATACAGTAATTAAC CGTAAAGAGATAGAGAAATACTCACATGTAGCAACTTTGGATGAAATAAA AGAAAATGATTACAATTTAAATATTCCTCGATATGTGGATACTTTTGAAG AAGAGGAGGCTATTGATTTGGTGGCGCTTGGTAATGAAATGGTTGCATTA AATGCTGATATTAAAAAAGCCGAGACTGATTTTCTTGGTTTATTAGATGA ATTAGCTGTTACTGCGGATACGAAGGAAATAATTGAAGCTACTAAGGCGG TATTTCGATGA ORF2013 (SEQ ID NO:40) ATTATGAAAAGCAAAACAAAACAGATTATCATGATTGGAGTGGTCCTTTT TCAATCACTCTTCGCATACCCGTTAATCACCATGGCGGAAGAAAATGAAT CGAAATCAGTAAATACAGAAACCACGTTAGAGCCTAAAGTAGCTCTCGAA GAAAAAACGCCTCAGAAACCTACCCTTACCAATAATCTGAAGCAAGAAAA AACTGTCCTTCAAGCAGGCGAAACATATGAAACTGTTTTTCCTGATGCAG CTTTAGCTACTGTAATTGCAAAAGCAGCAACTGGTTCAGAGGATATCACG CAAGAAGTATCGCAAACAGACTTGAATAAAATCACTTCACTAACTGCTAC ATCTAAAGGGATAGTTGATTTAACAGGAATAGATTTACTTTCAAAATTAA CCTCTTTAAGTATAAGCGGGAACCAAATCACTGATATTTCTGCACTCAAT GGTCTCGTGAATTTGTCCAATCTAAATGTATCTAATAATAAAATAACAAG TTTCAACCTAAACGCGAATAGTAATTTACCTATGTTAAGCGCTGTTGATA TTCGTAGTAATAACTTAAAAAATATAAATGTTCAAGACCAACCTAAATTA CGCACCATTGAGTGTGACACAGGTAGTAGTTCAGAGTTGACAGAAGTTAC GCTAAAAAATCTTCCAATTTTGATAGTTGCAGGTAATGGCTCTAGTGCTT ATCAAAATGATATTGTTTTTTCGAGTACACCAGGATTAAGTAAGGTGATT CTAGAAAATTTACCATCAATAAGCTCTTCAGTACGATTAGATCGTTGCGC GATAGAAGAGTTAGTAATTAATAACCTTCCAAAAGTATCAATGGTAAATA TAAGTAACAACAAAATTACTACACTAGAAGGACTTGAAAATTTATCTGCA GTAAACACTTTATACGTATCTGAGAATTTAGTGACTGAAATAGAGAACCT ACATGCGTTCCCTAAATTACAGACACTCACCGTAGACAATAACCATATCA GTGTATTGCCAACAAGTTTGAAAACGGAAAATCCCGTATTAACAACGCTA AGTGCGATGAATCAAACAATCACTCTAAAGCAAAAAGTTATCGTGTCAGA CCTAGTTCTTGATAATGAAGTGAAGAATTTCGGTCAAATAACCACTGCCA AATCCATCTCTAATAAGGGAACCTATCAAAATAACCAAATCAAGTGGCTT TTTGAAGATATAAAAAGCGTGAATGCCGTTGATTATCAATTTAGTGAACC TGTTCAAGAGGCAACTATTCAAGGAACTTTTTCGGGGAAAGTGACACAAC CAATCAAAGCATCTAAAGTACCAGTTATTAGCGCAGATGCAGAGATGAAT TACCCGAAAAACGAAACGGTATCAGAAGCTGCCTTTTTCAAAGATATTTC TGCAAGCGTAACGGATGATGCAACACTAACTTCTGATTTTGAAAGTGTTG TGGACTTTGCAAAAGCGGGAACGTATGAAGTGACATTAAATGCAGTGAAT GAGGATGGAGTAAAAGCGACTTCGGTGACTGTATTAGTGCATATCGCTAA GTCGCCAGCGCCAGTAATTACCGCAGATAAAGAAATCACATACACTAAAA ACGCGGAAGTCAGCATCACGGAATATCTTGCAGCGATTCATGCTAAAACG AATGATGGTTCACCAATTGAAAGTGATTTCGCTACGGCTGTAAATTGGGG CACTGCAGGAGATTATACCGTAACGCTAAGGTCTACAAATGAAGATGGAG TTGAAGCAATCCCTGTAGAAGTAACTGTGCACATCGCCAAGTCGCCAGCG CCAGTAATTACCGCAGATAAAGAAATTACGTACGCTAAAAACGCGGAAGT CAGCATCACGGAATATCTTGCAGCGATTCATGCTAAAACGAGTGATGGTT CATCAATTGAAGCTGATTTAGATACGGCTGTAACATGGGGCACTGTAGGA GGTTATACCGTAACGCTAAGGTCTACAAATGAAGACGGAGTAGAAGCAAT CCCTGTAGAAGTAACTGTGCACATCGCTAAGTCACCAGCACCAGTAATTA CCGCAGATAAAGAAATCACGTACGCTAAAAACGCGGAAGTCAGCATAACG GAATTTCTTGCAGCGATTCATGCTAAAACGAGTGATGGTTCACCAATTGA AAGTGATTTCGCTACGGCTGTAATATGGAGCACTGCAGGAGATTATACCG TAACGTTAAAATCTACAAATGAAGATGGAGTAGAAGCAATCCCTGTAGAA GTAAAGGTGCATATCGTAGAGCCACTAGCACCAACGATTTCGAATGTGAC ATTTGATGTGGATGATGTACAAACGACAGAATCTCTTGAAGCTGGAGAGC TAATTTCTGAACCATTGAGCCCAACAAAAGAAGGCTATACTTTTATTGGT TGGTATGACTCGAAAACTGGTGGTAATAAATGGGATTTTACAACAGATAA AATGCCAGCATATAATATTATTCTTTATGCTCAGTTTAGTAAAGATACAA ATAAAGCAGAAGCGGCCGGTGGAGATAAGCCCTCAACACCCTCTTCTATA AAAGTAAGTCCAACAGGTCAGTCCGAGAGTGGAAACTTGGAAAATAGATC TAATATTAAATTACCAGCTACAGGCGATGATAATGCAACTGTTTTATTAG TGGGCTTTGGATTACTAATGTTGGGGCTTTTCATTCGCCTTACTCAAAAA AAGCGTGCTAAATAA ORF2017 (SEQ ID NO:41) ATTATCTCTTGGAGATTTGTTAATAAAAACAACCAGAATATGAGAAGGAG GAAAACTAATATGATAAAATCGTTGTACATACGTCGTTCCTTGATGATGC TAATAACAAGTTTACTAGTAGTAAGTCAACTAAATTTAACGGTTTTTCAA GCATTTGCAGAAGAAAAAGGCGAAGAACCACTTTCTTATGAAGTTCAAGA AGAGCTTTCAAAAGATAAAAAGAAAGCAAAGCTTAAAATTAAAGCAACAT CTAATAATAATCAAGTTGAAATTCTAAGTATTGAAACACCAGACGGTAAT AAAATTGAGGGAAAAGAAGCCGAGTATACGGCTGAAAAAAATGGTGATGT TAATTTTATTATTAGCTATAAAGAAAACATAGAAGGAAAAGAAACAGAGA TTAAAACATTTAAAGCCTCCTATGAAGTAAAAAATTTAATAATTGAAAAA GAAGAAGCTAACCAATCAAAAGATTCAGTTAAACAAAATGAAACAAAAGC ACCTCTAAAGAATAATCAACTAAAATCAGGTAATGATGCTACTGTCACAT TAAATATTCCTGCTTATGATGGTACTGCTTGGGCAAATGGCGATATCAAA GATGTTAATGTTACAGTAGACTTTAGTAATAGTACATCTACTAGTAAAGA GGTGGAATTCACACTGCCAGACGGTATGAGATTTGTATCAATTCCCGTTC CCAGCAGTTTTCAAGTACCAACAGGTGTGGACTCTGGGGTGATAAATCGT TTAAGTGCGGGGGACCCGATTGGTACTGCAATAACATCCGTTACTATTCC AAACAAAGAAACAACCTACGATAAAGCTACTTTCGGGACAGTTAATTATA AACTTACTCCAGGAACAGAAAAAGTAAGTTTTAACTTTTCTGTTCGTGTA GATGCTAATAAATACTATGGTGCAACTGATCTAAAAGCCCCTATTAAAGT AGAAGCTTTTGTGGGAGATAATAAAATGGCGATTGCTTCAGAAGAAAAAG CAATTCGTGCAGAAGGAAATAAAGTGGTTGGTTATGCTAATCAAACACAT GTAAGTACTATGTTCAGAAATTGGTATAAATCTTTTAGAACACCTGATGT ATTAGCGAGTACAGATGATGAAGATTCTTATGCATATACAAAAAGTTACT CTGTTGTAAATGGAATGAATCAAGTAGATGAAAGAGGAACTAATATCTTT TCACCTAAGAATGTCTCGACTACCCTTTATTATCCAGAAGGTATGGAATA TGTCGGGGTAGTAAATGAAAAATATGCACTTTTAAATGAGAATGCTAATA CTACGATTACTCATTATCCGGAAGAGAATAAAGTGGTGTTCGATTTTAAA CAACAGAACTTTAAAGGAGTAACAGATACGGTATATGCGATAAAATATAA AATACCAAAAGGAACGCCAGCAGGAACATATACCGCTCCTAAAGTGCCAC ATGCAGTCATCACGACATATGACGATAAAGTATTTGAATCTGATGCATTA ACAAACAATTCTACAGATTTAACAACTAAGACAACGTTAGATGCTTGCCG AGTTGTAGATTCGACCGAAAATAAAATGGCACTAATCGTGGGAAACAAAA ATATTAATCCAGATAATGAAACTTGGGCAGGGAATGTTCGAATTAATAAT AAAGATACTGCCGGGACAAAAACTAATCAAGTCTTCCAAATTGAATTTGA TTCAAACTGGGAAGCTTCAATTGTTAACATCCCATTTGATGGGAATAGAA AAGATAATGATATCACTAATATTCAATACAAAACTAATTTTGATGATACT TATCAAACATACAATGGGAATCTTCCTAAGAATAGTATGAAAAATATTGC TATCTTAGAAGCTGATGCAGTCGGACTTCAACCAGGAGAATACTTTACTG AGGTGAAAGCGAATGTAGGCGATTTTTCTACAGGATATACAAGCTACTCA GAATCTGGTGGTTTTGGTGAGGAATCAACAAACTCCTATGGTATTGTCAA ACCAGGCATTTCTTCTGTTCAATTTAAAGTATCCATTTGGGATGAGGCAG ATGAAGTAAATACGAAAGTCTCGGGTACTTCTGTTTATAGTGTTGCCGAT AATATTACGACAGCGGCGAACGGAACAGCTAATTTTTATAATGAACAAGG ACAAGTAATCAAAACTGCTGGAGCTGGAGATAAATTTACTACAAAAGCTA CATTGGTATTATTTAACTATCCATACGGGACACGTACAGTCCTTAATGAT CCTGAAGTGTATCTTCGTCAATTGGATGGTACTAAAATTCTTCCGTCTTC TATTAAGTTAACGGATCAAGATGGAGAAGAGATCGAGTTCTCTATTAAAA TAGAAACCGCCAAGAATGGAGAGAAAGTGTATGTTTTAAAAACAAAAGAT GCAACAGTTGGTAGGTATGTTGGTTATCCTTCTAAACATAAATTTTTAAA TATAAGTTATGATACTACGATTGATGTAACATTAGATAAAAGTCTTCATA CTGACATCCAACAACTTCTTGCTTGGGGAGGCCCAAATGTAAAAGCTGCT ACAGCTGCGAATACTTTCATGGATACAGGTCTTGATGTCAATCAAAATGG AATAGAAAATGAACGTCTGCTTTCTGCGAATAGCAGTACTTTAAGTGTTC CAAAGCAAGATGCAGTCACAGTAGAAACATTCTTAAATTTGGCTGGAGAA GGAGCAAAAGCATCTTATGTAGAAGGTGACGATAGTACAGTTTCCTATTT TACACCAGGAACGGAAGCGGATTATACAGTCCGTGTTACAAATACATCTA CTGGTATAGCAAGTGCTTTTGAACTCTATATTCCAATTCCAAAGACCGGA CAAAATTTTGGTTCTAAATTCCAAACGGAGACATTTAAGTGGGATATGAA ACTAAATGATGCTGTGCAATTAACAGATGAACAAAAAGCACAATTTGATA TTAGTTATGCAACAGAAGCAAATAAAAATAACTATGAATCAGAAAGTGTC TATAGCGCTGTTCCCTCTGATTATGGGAAAGTCAACATGGTTCGTATCAA AGTGAAGACAAAGATTGATCCCGGTGAAACACAAACAATCAAAGTTCCAC TAAAAGTAGATGAAACTTTTAATTCTGCTACAGAGGGAAATAAAATAAGT GAACGCGATGTATATAACCCTTACTATCGTGTAACTACGAATGCTTATTC TGGAACATTACCAGGAACTAAAGTTGGAGCAGAATTAATTATTTTAGAAG CAAGCGGTTTTCTTTTCCAAGATAAAGATGCAAATGGTTTGTATGAAAAA GCTCAAGGAGATACAGCACTCGCAAACGAAACTGTTGAACTTTATAAATG GAATGAAAATACCTCTAACTATGAGCCGTTCTTGAAAAATGGTGAGCCAG TCAGCGTTAAAACTAATGCTGATGGAAAATACACCTTTAATTACAATTTG AATTTATCTTACGGGAAATATGCAGTGAAGTTTCCAGAAAGAGCTGGAAA TCAGTTTACTTTGAAACAAGTGGGGCAAGATAATACGATAAATAGTACTG TATCCAATAAGGGTACAGACAAAGGTTGGGTAAAAGAAATTGATCCAGCT CAACCGGTATCACAAAACATTAATGCTGGTTACATGGAATACGCGCCGGA TAATGATCTTAAAGTTAATCTTAGCGCCAAAATCGTACAAGCTGGTAAAA GTTTAAAAGTAACATTGCCGAAAGTAAGAGCAACTAGTGGAGAAGCGGTA GAAGATACGATTGAGCCGTCGTTCTTTCACAATATTCAAGCGATTACAGA TGGTTACAAATGGACTAGCAATGATACGACTTTAGCAACTACACAAACTG CTAATGATGGTTCTGGAATAATTGTTGGTATTTCTGCCGGAAACAAAGCA ATCGCAACAACTGATATTGGTATTACAATCAAAGATATTTTTGATACAGA GAAAAAATCTACTGCACCTGTATATATAACTGAGCCAAGTGCTACGATAG ACCAAAAAGAGGGACTTATCCTTGGCGCATTGAATTTTAGTTTAGAATAC AAAGATTCAAATAAGCTAACTGAAACGGAAGCAATTACTTTAGCAAAAAC AGCTAGTTTTGAAGAAGTGAAGACAGGTGTACTTTCTACTGCACAAGATT GTACTAGTTCCGTAAAAGTGGATGCCAAGCAATTAAAAGCTATCCAAGAA GGCTCTAACCAAGGCGGAACTTACCCGTTGACCTATCAAGTTGCTAAAAA TGGGAAAACAGCGGAAGTAGTTATTCAAGTGAAAGTTGAAAAAGATTTAA CAACTGTCAATGTACATGATTCTATTTTGTATTTGGGTGATACATGGACG GCAACTGATAACTTTGATAGTGCGCTAAACAAAGTAGGTGAAACAGTTCC ATTTGGAGACATCCAAGTAGAAGGATCTGTTGATACTAATACAGCAGGAA TCTATTCAGTCACATATACGTACAAAGGAGTGTCTAAAAAAGCTAAAATT GAAGTTAAAGAAAATTTGACAGAAATTAATGCACACGACTCGACAATTTA TACTGGCGACACTTGGCGAGCAGGTGATAATTTTGACAGTGGACTTGATA AAGATGGCAATGCCTTGAGTCTAAAAGATTTGACGGTTATTGGAACAGTA AACACAAACCTAGCAGGCGTATATACGATTACGTATAAGTATGAAGATAC TGTAAGTTCAATTACTGTTACTGTAAAAGAAAATAAAAAAGGAATTAATG GGCATGACTCGTCAATCTATGTAGGAGAAGCATGGACAGCGGCGGATAAT TTTGATAATGCAGTTGATAAAGACGGGAAGCCAGTTTCTTTTGCTGATAT AAAAGTGAAAGAAGAGCCTAAAGTAGATGTCAACAAAGCAGGCAGATATC AAATCACCTATAATTATGATGGTGCCTCGACTACTGTTACTTTAACTGTG AAAGAAATCAAAACAGCTATTAATGCACATGATTCTATTCTGTATATTGA TGATAATTGGTCAGCAAAAGATAATTTTGATAGCGCTAGGGATAAGGATG GAAATATAGTATCCTTTAATGACGTACAAGTCTTGGGAACTGTTGATACA AGTCAAGCAGGAACATACCCGATCACATATGTTTATGCTGGAATTACCAA AACCATTCAAGTAATTGTTAAACATCCCAAAACAGCTGTGCGAGCCCATG ATTCAGTGATTTATGTTGGAGATAATTGGAAAGCTCAAGATAATTGGGAC AATACGCTCGATAAAGCTGGTCAAAAAGTGAAATGGAAAGATATTACTGT CAAAGAAAATCCTGCCGTGGATGTAACAAAGCCAGGCGTCTATGAAGTTA CCTACAGTTATGACGGTATTTCTGCCACGATTAATGTAACCGTGAAACCA AGAAAAACGACTGTAAAAATTCATGATAGTAGTTTTTATGCCGGAAATAG TTGGAACGCGAAAGATAATTTTGACCATGCAACGAATAAAGCAGGTGAAA AAGTAGCATTCAAAGATATTACTGTCGCAGGTAATGTTGATAGCAAAACA CCAGGAACATATGAAATTAGCTATGTATACGATGGTGTGAAAGCTGTTGC TAAGGTCACTGTTTTGAAAAACCATTCTATTTTGATGGTGAAAGATCGTG TCATAAAAGTAGGCGAGAAATGGAACGCGAAAGATAGCTTTATTCAAGCA ACTAGACGTGATGGAAAAAATATTCCATTTTCACAAGTAAAAGTGCAAGG AAAAGTAAATCTGAACAAAGCAGGCAAATACCAAGTTATATATTCAGTAG ATCCAAATGAAGGAACTGAAGACGCAGGGAAACAAATGTTGTCAGTAACT GCTACTATTCAGGTTGAAAATAGAGGAGATGCGGGGTTACAAGATAATGA ACCACGAAGCGTAAAAGATAACAATCAACGCGCTGCTAACTCCAACGATA TCAAACTCATTCCTAAAACAGGAGATCAAACAAATCAGTGGGTTTTATGG GCTGGCCTTTGTTTGACTGGTTTAGCAATGCTTCTATGGGGATTTGCTCT AAGGAGACGAAAAGTGAAATAA ORF2019 (SEQ ID NO:42) AAATTAACTACGAAAGAAGGAGGGGAGCTGATGAAGAAGTTTTCCATGCG AGTGGTGCTTATTATTTCTGTGCTTTTTATTGCACTGGGGAACGCTAATG TTTCTATCGCACAAGAAAGGGACACAACGAATAAGCTTCCAGAAGAGGAG CTGGGTTCTCTGGATACCTCTAATCTTATTGCAGAAGAAGTTGCGCAAGA GAAACCAGCCGAGGTCGAGAATCTAGAAGAAATCCCAACTACGGATGAGT TGATGCAAAATCCAGAGGTTCTGGAGAAGTCTGTTGCCGACTCGGATGAT CCGGATTTAACAGTGGTAAACTCGGGTGCTTACTGGACGCTTTATTATAA TTCTGCGAACGGTGAATATAGCTTGCGTATGTTTGGCAACGTACCAAGTA GTATACCAAGCGCTTGGAAGAGTTATTTGGGTAACATTAAACATATAGAG ATTGAAGAAGCTACTTTGACAGGAAGTTTTGAAGCTTATTTTAAAAGTAA AATAGATGGTTTCAGAGTGCTTGAGAGCGTGAGAATTGAACGTTCTAATT TGTCTGGAGTAACATCTTTTAGAGAAGCATTTTTTAGTGCAGGAATTGAA AAAGTTATCATTAGAGATAATGATTATCCGACAGCACCATCTTTACTCAC TACGGAAAGTATGTTTGAAAATTGTTACAACCTTACGGAGTTTGATGTGA GTGGTCTTGATACTAGCGCAGTAACTAATATGAAGAAAATGTTTTATAAC TGTAGAACACTTGAGGAATTGGATTTAAGCAACTTGGATACGAGTTCCGT TAATAGTATGAATAGCATGTTTGGATACTGTGAATCACTTGAGAAATTGA ATGTAAGTAATTTTGATACGAGTTCTGTGAATGATATGTATCATATGTTT AGGGATTGTAAAGCACTTGAAAAATTGGATGTAAGTAATTTTGATACGAG TTCCGTTACTAATATGGGAGGCATGTTTGTTAATAGTACCAGTCTTAAAG AATTAGATGTAAGTAATTTTGATACGAGTTCCGTTACTAATATGTCAGCC TTGTTTAGTTCCTGTAGAGCACTTGAGAAATTGGATGTAAGCAATTTTGA TACGAGTTCCGTTACTACTATGTTGGCCATGTTTGTTGCTTGTAATAGCC TTGAAGAGTTAGATGTAAGTAATTTTGATACTAGTTCAGTAACTACTATG CAGTCCATGTTTTTTGAGTGCAGCTCACTTGAAGAGTTAGATGTAAGTAA TTTTGATACGAGTTCAGTAACTACTATGCAGTCCATGTTTGAAAAATGTA CTAGCCTTGAAGAGCTGGATTTAAGTACCTTTGATACGAGTTCAGTGACT AATATGCAGTCCATGTTTATAAATTGTGCAGTGTTAAAATCTTTATATCT GGATAATTTTACTACCGCAAAGACCATGACAGATATGTTTACTGGAACAA CCTCCCTAGCCTACTTGTTTGTCAGTCACAATTTACAATCTTTTTATGGG TTGGCAAATACAAACTGGTATGATGAAAAGAATTGGGTACAGTTTTCTAA TCTCTCTCAACTACAGACCTATCATCGAAATCAAAGTGAACCTACTGGCT ATAGAAAAGGTACCTTCCTTTCCCTAACAATGGATGCGATGGGTGGGCAG TTTGATGATGCGGAGGAACAAAAAGTACAAAGTAAAATTTCTGGGGAATA CTGGGAAGAAGTGATTCCAGTAAAAGAAGGACATTACTTTGACGGGTGGT ATCTTGATCAAAATTTCACTAATAAGTTTGATTTTTCTTTACCAGCAACT GTTTCAGCAACCCTCTACGCCAAATGGGTTGAAAATTATACAGTGATTAT TCCAGCGTCTATTTCCTTAAATGAAGCTACTGAATTGAAGGTAGAAGGGA TTAATCGTGGAAGTAAAACTTTGTCCGTGGGATTAAACCGAACAGCAACG TCTGTTTCTGAGAGCAACAAGCTAACTTTGGCCAATACAGCAGACACAAC AATCCAATGTTTGGCACCACTAAGTTGGGACGGTTCCGAAAACAATCCAA AAAATGCCATTTTAACCCTAGCACCAGGTTCGGAAATAACAGAAGGCGAT GCAGTCATGGCTATTGAAGCACCAGAGAATATCCAGGCAGGAACGTATAC AGGGAATCTGGTATTTTCGATTAATTATGAATAA ORF2074 (SEQ ID NO:43) AGGATAGGAGATAGATTAATAGTGGAAATAACAGAAACGAAAGAATGGTG GAAAGAATCGGTAGTGTACCAAATCTATCCGCGTAGTTTTCAAGATTCAA ATGGGGATGGTATTGGAGATATTAGAGGAATTATAGAACGACTTCCTTAT TTGAAAGATTTAGGTATTAATGTGATTTGGCTTTGTCCTGTCTATAAATC ACCTATGGATGATGGTGGTTATGACATTTCTGATTACTATGAGATTGATC CAATGTTTGGAACGATGAGTGATATGGATGAATTAATTGAGAAGGCAGAA AAATTAGGAATAAAAATATTGATGGATTTGGTGGTAAACCATACATCTGA TGAACATGAATGGTTTGAAAAAGCAATAGCTGACCCAAAAAGTAAATATC GAGATTATTATATTTTCCGAGAGGGTGTAAATGGAAACCCGCCTAATAAT TGGCGTTCTTATTTTGGAGGATCTGCGTGGGAAGCCGTACCAGGTGAGGA AAACATGTTTTACCTACATGCTTTTTCTAAAAAACAGCCAGATTTAAACT GGGAAAACATTGTAGTGCGTAATGAATGTATCCAAATGATTAACTGGTGG CTTGAAAAAGGTTTAGGTGGCTTTAGAATTGATGCCATTTTAAATTTGAA GAAAAGAATTGAGTACGGTACTTTCCCAGCGGACGGGGAAGATGGCTTGG TTTTCATCGGTCATTGGATTTTAAATCAGCCGGGAATTGAAGAGTGGCTC AAGGAGATTGACGAACGGACATTTAAAAAACATAATGCATTTACTGTGGC TGAGGCGGATGTGCCTGAAGAAAGACTTTCTGAATTTATAGGTGAAAATG GTCATTTCCGTATGGTGTTTGATTTTAGCTATACAGATATTGATACTCCT GAAACAGGCGAATGGTTCAAGAATTCAGAATGGACAGTAAAAGAATTAAA AGAGAAAATAATTACCAATGAACTGGTGACACAGCGAAATGGTTGGGGGG CAAAATACTTAGAAAATCATGATCAACCGCGTTCGATAAATAAGTATTTA CCTCAAGAATACCAAGATGATCGTAGCAAAAAAATGCTAGGCACGTTATT TATGATGTTGCACGGTACGCCGTTCATTTATCAAGGACAAGAGATTGGTA TGAGTAATACTCGGATGGAAAGTATAGATGATTATAACGATATTGCGACG CACGATCAATACCATCGCGCAATTCTCTCTGGAATGAGTCCGGAAGAAGC GCTTGAAGGAATGTATCGGCGTAGTAGGGATAATTCAAGAACACCGATGC AATGGAATAATCAAAAGAACGCTGGTTTTTCCGACTCAGATGAAATTTGG TTGAAAGCAAACCCTAATTACCTTGATATTAACGTAGAGCAGGAACAAAT CGATGATAATTCCGTATTGAATTTTTATAAGAAATTAATCCATTTAAGAA GTGATTCTAGTAAATATAAAGAAGTGGCTGTTTATGGAGAATTACTGCCA GTAGAATCAAGTGATGAAGTTATTGCTTACAAACGTAAAACAGATGACGC TGAGCTCTTAATCATCGTGAATTTTTCTGATTCTGAAAATCAATTATGCA TTGAAGGTACTTATGAACAGGTACTTGCTAATGTAGCGTTGCCAGAAATG GTAGAAAATGTCCTTGAAATACCTGCATATACAGGTGCCGTCTTCTCAAG GGTTTTGGAGGTAGACTGA ORF2075 (SEQ ID NO:44) CATTCATTCTTAGCGCGGCATTCTCGTTATTTGCCTACACACGTACAAAT TCTTATAAAGAAGGGAGCAACTGAAATGAAAAGAGCTACAGTATGGCCTA ATCTATTGTTGATAGTGCTCGGGTGTATCTGGATATTCCCGATTATCTGG ATTGTTTTGACAGCTTTTAGAGCGGAAAGTGGACAATTTGTTTCGTATAT CTTTCCGAAAGAATATACGCTAGATCATTTTGCGTACCTATTTGAAAATC ATGAAAATTTTCCTTTTATGTTATGGGTTAAAAATACAATGATTGTTGCG GTGTGTTCCTGTTTATTGAGCACTTTTATAACCGTTTCGATGGCTTATGT GTTATCTAGACTTCGCTTTAGATTTAAAAAGACGATGTTAAAAACAGCGC TAGTTTTAAATATGTTTCCTGCTTTTATGAGCATGATAGCAGTTTACTAT ATTTTGAAAGCATTTGGATTAACGCAATCTCTAACGGCGCTTGTGTTAAT TTATTCATCTACAGCTGCATTAACTTTTTATATTGCAAAAGGATTTTTTG ATACAATACCAAAATCTTTGGACGAATCGGCAATGATGGACGGGGCGACG AAATTAAGTATCTTTACAAAAATAACTTTACCAATGTCTAAGCCTATTAT TGTATACACAGCTTTAATGGCATTTATGTTGCCTTGGATGGATTTTATTT TTGCTAAAGTGATTATGGGAGACAATGTGCCTAAATATACAGTGTCGATA GGTTTATATTCCATGTTGAATCAAACAACGGCAAATACAATGTATACAAC GTTTGCGGCTGGCTGTATATTGATTGCGGTACCAATTACAATACTGTTTA TTTATTTGCAAAAATATTATGTTGAAGGCATTACAAGTGGTGCTGTTAAA GGATAG ORF2076 (SEQ ID NO:45) GTTAAGTATATGATGGTTAAGAAGAATTATTTTAATATTTTTAAGAATGG TTCTGTTTCTACGAGATTATCTTATGTAATTATGGGGGCTGGTAATTTGG CCCATAAGCAAATTGCGAAGGGACTTCTATTTCTTTTTAGTGAACTTGCT TTCTTGTTTTTCCTTGTGTTTTATGGCATTACCTTAATTCAAGGTATGGC GACATTAGGGACAGTTAACCAATCGTGGAATTTTGATAAGAGTTTAGGTA TTATGGTTCGAACACCGGGCGATAATTCCATGCTGATGCTAATATATGGG ATTATGACAGTTGTTATTTGTGTACTATTTCTCTTCTTGTACCTTGCTAA TATTAGAAGCGCTTGCCAGGTGGAGGGCTTCCAGCGGGAAAATAAAAAAA TCCCAACATTTAAGGAAGACTTAAAGAGTTTGCTAGACAATAAATTTCAT GTAACTTTACTGACGATCCCGATGATTGGGGTTGTGGTGTTTACGATAAT GCCACTTGTTTATATGATTTCTTTGGCTTTTACCAATTATGATCATGAAC ATTTACCGCCAAGGAATTTATTTGGATGGGTAGGATTTGTTAACTTTAAA AATGTGCTAAATGGTGATATTTCCAGTACGTTCTTTCCGGTGCTTGGATG GACACTTATTTGGGCGCTTTTAGCTACTGCTACTTGTTTCTTTTTTGGCG TATTGCTTGCACTTCTTATTAATCATAAGGGTGTTAAATTCAAAAAGTTT TGGCGCACTATCTTTGTTATAACTATGGCGGTACCTCCGTTTGTGTCACT TCTCGTAATGCAGAACTTGTTGCATGCAGCAGGACCGCTTAATACGATGT TACTTAATTGGGGAATTATAGCTGAGCCGATACCATTTTTGACAGATGCT TTGCTAGCAAAGGTATCCGTCATATTTGTCAATATGTGGATTGGGATTCC GGTAACTATGTTAATCGCCACGGGGATTTTAATGAATCTACCGAAAGATC AATTGGAAGCGGCGCGAATGGATGGAGGTAACAGTTTTCATTTATTTAGA TACATAACTTTCCCTCAAATCTTAACGGTGATGTTGCCAAGTCTGATTCA ACAATTTATTGGAAATATAAATAACTTTAATGTGATCTATCTCTTGACTG GTGGAGGACCTTCGAATAGTAACTTCTATGGTGCTGGGGATACGGATTTG CTCGTGACATGGCTTTATAAATTAACAGTAGAAGCTGCGGATTATAATTT AGCTTCGGTTATTGGGATTGTAACATTCATTCTTAGCGCGGCATTCTCGT TATTTGCCTACACACGTACAAATTCTTATAAAGAAGGGAGCAACTGA ORF2110 (SEQ ID NO:46) ACAAAAAAAGGAGATGCAACTATGAAAAAGCTTAGAATATTTACTTTGAT GCTTGCTTTTGCTCTATTTTTATTAGGTGGAGGAATTGTTGCACAAGCAG CAGAGGAAGCCCCAATCGATGAAAAGATAGTTGGGGAAACGGTAACAAAT GACGGAGAAGAGTTTATAGTCGATGAGATTAGTGATTTAGAAGATGTTAA TTCAACAACGGGGACGTTAGATACATCTGATGAAGTTGAGGTTGATTTAT CAGGATTAACTATTGAAAATGAGGAAGCCGTTCTAACCCCAGGTTTAAAA ACGATTTTTGGCGGAGATGGTAGAAAACTTGTAACAAATACAACTCAATA TCCATATTCAACGAGCGCTTACCTTGTAATGGAATTTCCAAATGGAAAAA CTTATATAGGTAGTGGACAATTGATTGGTGAAGATTCTGTACTTACAGCC GCTCATTGTTTATATGGTAAAAAAGATGGTGGATGGGCAAAAAAAGTGAC TGTATATCCTGGATATAATGGCACGAAAGCTCCTTTTGGAACAGCAAAAG CAAGAAAAATGTATGTTCCAAAAGAATGGACAAAAAAAGAACCTTCTACA GAAGATTATGGTGTTATTAAATTAGATAAAAATATTGGGACAAAAACTGG AACAATGGGGTTAACAACTAATACATCTGGTGCAATTACTATTAGTGGTT ATCATGGTGACAAAAAAGGGAAATTGTACACTCAAACTGGAAATATCTCT CAAGTCACTGCAAATAATGTTTTTTATAGATTAGATACAACAGGTGGTAG TAGTGGTAGTGGTGTTTATAATTCTAAAAAACAGATTTTAGCAGTAAACG CATATGAATATTTAAATGGTACCGGGGACAACTTTGGTACAAGAATAACA AAAGAAAAACTAAATAATATTTATACTTGGGCGTTTGACAATAATCTTTC TGTAAGCAAACAAAAAGGGATAAATTACGAGCTCCACGTCCAAAGTAAGG GATGGATGGGAAACGTTGCTAATAGTATGACTTCGGGCACAGTTGGCCTT GGCTTACGAGCAGAAGCAATGAAAATTAGTTTATCAGGGATGCCGTATTC TGGAGATATTCAATATCGCTCACATGTACAAGGTAGTGGATGGCAAGGTT GGTTGAAAAATGGGGAAATTTCTGGAACTCGTGGACAGTCAAAACGTCTG GAAGCTTTCCAAGTAAAATTAACTGGAAATATGGCTAAAAATTATAGTGT GCAGTATAGAGCGCATGTCCAAAATAAAGGTTGGCAAAGTTGGGTTAAAG ATGGAGCAACAGCAGGAACAACAGGAGAAAGTTTAAGAATAGAAGCTGTA CAAATGCGACTAGTTGCAAAATAA ORF2192 (SEQ ID NO:47) GCTAAATTTTTTATGGGAACTATGAGGTATGATATAGAGAAAATTACAGT AATAGTTCATAACAAAATTGCGAAAGGACGTATTTATGTGGCAGAAGCAA AATTTGAAGCAGCTTTAATTAAAAAGCTTGAAACTGAAGGATGGACTTAT CGGGAAGATTTATCCAATGTTAGTATTAAAAAACTTGAAGAGCATTGGCG TGATATCTTAAATGAAACTAACGCTCATAAACTCAATGGAGTACCATTGT CAGAAATTGAGTTTGGATTAATTCTTCAAGAATTACAACGTATTAAAACA CCGTATGATGCTCAATTATTATTAGTGGGTGCAGGTGGAGTAGGGTCAAT TCCTATTACTCGTGATGATGGTTCAAGCCTGGAAGTTGAAATTTTTTATG AAGATGATGTAGCGGGCGGGCGCTCTCGGTATGAAATTGTCAATCAAGTA AGATTTGATAATCTACCTAAAGGATTAACAACAAAACGTATAATTGATGT AGCTTTACTTATTAATGGTATTCCAGTAGTTCATATTGAAGAAAAAGATG AGCATTTACAAAATCAGTGGCGAGCTTTTGAACAACTCAAAGGTTATCAT GGTGACGGACTGTATAAAGGATTGTTTGCTTTTGTACAAGTTCAAGTTAT CATGAGTCAACATTCGGCGCATTATTTTGCTCGTCCAAATGCATTTGAAC AATATAATAAAACTTTTGTGTTTGGCTGGCGGGACGAAAATAATAAAGAT ATTACGGATGCATTTGAATTTATTCATCAAGTAATGAGTATCCCTGCTCT CCACCGCTTAGTTACAGTTAATATGATCCCGGATGCGTCAAATGATAACA TAATGGTAATGCGCAGCTACCAAATTCAAGCAACAAGAGAAATTTTACAA CGCATGAAAGAAATGGAAGCAAGCGGACTTGTGCAAAAAGAGGGCGGGTA TATATGGCATACAACTGGATCAGGCAAGACAGTTACTTCCTTTAAGGTTG CACAACTCTTAGCGTCTGCACCTAGAATTAAAAATGTACTATTTATTGTG GATCGTATTGACTTAATAGACCAAACACTCGAAAATTTTAAAAGTTTCGC ATATGCTCACTTTAAAAATCGCATTAAGAAGGTTAATGGAAGAGAGTTAA AGAGAGAATTAAAGAGAAAAGGCTCCTCGCAAATTTTATTGATTTCAGTT CAAGGATTGACAAAAGCTGTTAAAAAAGGTTTAGAAAATGACGACTGGAA TGTCATTATTATGGATGAGGCGCACCGAAGCGCGAGTGGAGAATCTGTAA AGTTAATCAAAAAGGCACTCAAGAAGACAACTTGGTTCGGGTTCACGGGC ACTCCGAACTTTTACAGTGATGAAATAAATGATGTCAAAACAACTCGAGA AATTTCAACGCATGATATATTTGGCAAACGACTACATACATATACCATTA AAGATGCTATTGGCGACGGAAATGTCTTAGGATTTGATGTAACTTATTTC AAACCTCATTGGGTGGTTGAACATCCACAAGAAGACTTTTCTGAAAAAGA CTATGAAAAAGAAGTTTATCAAAGTGATGTCTATCGTCAAGAAGTCGTAA AAGATATCCTTGATAACTGGACGAAAACATCTAGTGGGGCTTTAATTGCA GGTAAACGTGAAGAGAATGCCTTCCAAGCGATGTTTGCAGTGTCAGGTAA GCAAGCAGCTGTGAATTATTATAATATTTTCAAATCGAAAGGATCTCATT TAAATGTAGCAATGACATTTTCACGTGATGAGTCTAATGAACATGGTACA AAGGAACAAAATGAGGCGCTTAAAAATGCGATTAAAGACTATACTGAAAA ATTCAATGTTGCAAGCATTTTAGACGCAAAGGATCCAGCTCGAGCTTACA TGTTGGATATAACTAAGCGATTAGCACGTAAAAGACCATATAATCAAGGT AAAGAAGAAGATAGATTAGATTTAGTAATTGTTTCAGATCAGCTTTTAAC AGGCTTTGATTCAAAGTTCATCAACGTAATCTACATGGACAAAATGCTCA AAGAAGGAATGCTAATACAGGCGATTTCTAGAACAAATCGAACTTTTGAC CTTAATAGCAAACCACATGGGAAAGTACGTTTTTATCGCCAAGGTGATGA AATGCGCGAATTTGTTGAAAATGCGCTACGTATTTATACGAGAGGTGGCA ATGATACTCTTCAAGAAGCGGAAGAAGAGACAAAAAATCAGCTGCCTAAA GATTTAGAAAATGACGATATTCTTGCAAAGCCCCAGAGCCACCAAATCAA CGAACTAGAAGAAGCTATCTTAAGATTGAAAGAGCTTGCTGGCGATGATT TTAGTCAAGTTCCACGAGGCCAAAATGATCTAAAAGAATTTGTTGGTCTT GCTTTAACTACTCAAACCAAGATCCAGCAATTAATCCAACAGGGTTATGA GCTAGGAAGCGAGATTGAGGAGCTAAATGAACAAGGTGAAGCGACTGGAA GAATGGTTCGTTTGAACATTTCAAGTATTGATGAATTTGGTGCTTTACAA GCTCGTTTATATGATGCTAAGGAGAAATTACCTCCTGAAGAGCGTCCAGA TCTCACTGAAATAAAGATTGGAATTGAATTTTATCATCACGAGATAATTG ACTATGATATGTTAGTTGAGCTTCTGAATACCTTTATGGACGAAAAAAAT AAAAGTAATAAAGATGCTATCGAAAAACACATCGTACCAATGGATGAAGA AAGTCAACATGAAATCCATGGAATCGTGGATGATATTGAAGCAGGTCATA TCACAGAACATTTTACAACCGATTCTCTTCAGGAAACACGTAAGAAATAC CGCACGGAACATCGAGAGCTTAAAGTTCGCCGTTGGGCAGCTAACCAAAA AGTCAATGGTAATCGTATTGTAGAAGCTTTCGACTTATTCCTACCAGGGC ATACGCTTATTGATAATCCAAAGCTAGCGGATATTGTGCGTGAGATTGAA GAAGAGGAAAATATCGGATTTTTTGAAGCCTCTGATTTTGAAGAAGAGCT AATGGCATTCTTCAATTCACTATAA ORF2217 (SEQ ID NO:48) GAGGACATAATTATGATTAGAGTTGTAGATTTATTTTCTGGTGCAGGGGG TTTGACATTAGGATTTCAGAATAGAATTATAAATAACACCTTTTTACCTA TGTCTGATTATAATATTTTATTTGCTAATGAAGTGGATAAACACGCATCT GAAGCCTTCTCTCTAAATTTCCCACAAATTCCAATGTTAAATTGTAGTAT AACGGAACTAACCGAGGATTATTTAGATAATCATGAGATTGAGTATTCTA ATATTGATTTAGTAATAGGTGGCCCTCCCTGCCAATCCTTCAGTACAGTT GGTAGGAGGCAATATGATGAAAAGGCTACGATGTATAAGGAATACAGAAG AATGCTTTCCTTCTTACAGCCTAAAGTATTCCTTTTTGAAAATGTGACAG GTCTTTTAACGATGAAAAATGATGAAGGGGAACCTGTACTTGAAGATATC AGAAAAGAATTTGGCGATTTTTCTGACTTTGAAATTGATTTAACCTATGA AATTAGAGAAACAGTTCTAAATGCAAAACATTTTGGTGTCCCTCAGAATA GAGAGAGAGTATTTTTACTAGGGATAAGAAAGGATTTAGAAATTAAACAA AATTGGGAATTTCCAGAACGATTATTATTTGAGGATGATTTTTTAACATT AGAAGATGCTATAGGAGATTTACCTGCGTTGAGAAATGGTGAAAGGAAGG ATGCTTACGATGGAGATCCGTATACTCCTTATCAAAATTTAATGAGGAAT AATTCGACTATATTAATGGACCATTTCAATGGGTTAAACGGTGAAAAAAT GTTGAGAATTATGGAAACAGTTATTCCGGGAGAGGGGAAAAAATATATAA ATGAGTTAGTTGAATCTGGACAATTAGATTCAAAGTATTACCTAACATCT GGTTATAATAATACATATAGTAAACTTTGGTGGGATAGACCTAGTTCAAC AATTACTAATAATTTATCCACGCCATCTTCTTTCAGATGTATACATCCAA TACAAAATAGAGCATTAACCCCTCGAGAAGGAGCTAGGATACAGTCTTTT CCGGATACATTTCAATTTGTTGGCAGTAAGGAAAAAATTAATAGCCAAAT TGGTAATGCTGTACCTCCTTTATTAGCGATTGTTATTGCACAAGAAATAT ATAATTTTTTTGAAGAGAACAATTGGATATAG ORF2247 (SEQ ID NO:49) GGCCAGGCTCCACACGTTAGAAACCAAACAAGCCACCTTACAAAAGGAGT GGAGCAAGTGAGCCGGATAGATATTGCGGAATTGAATGACTTTCTCCACG GTTTGCGAAGTAGTAATGCGGAAGCCAAAGCGATGATTAGAAAAATTAAA GAAGCAGCGATGGATTACGCCCAGGACAATCGTTTAAAAGGGGAAGCAGT TAGTACCTCCAAACGGTATTTTTCTAGTACCTATACAAGTATTTGCCAGA GCATCATTGAGGCACTGGATGAAAGCGAAGAGCGACTAGCGCAATATATT CGCGAGTTCGGGAGCCAAGTGGATAGTTCGCCTTCTGCCAGAATTGATGC AGAAATCTTACAAGAAGCGATGGCCAAGGTTAGCCAGTTACAGCGAAAAG AAGAAGACTTGCATCGACAATTGACGGCGCCCAATACGAAGCCGGATATG CAACAAGTCTATGCAGTGAAATCAAGAAGTGTTCATACACAATTATTGAA GGCAATCGAAAAAGAGAACATCCTAGAAAGATATTTAGCTTTTGAACAAA GTCATGGCCAGTTTTTTAGTGCGTTAGACGAACTCATTCAAGCGACCGGA CGTGCGGTGCAAGAATTGTTACAACATGTGACTTTTAACGATAAAACAGG GACTTATTCCGTGCCGAAAAGTGCGGTAAACAGCTTGTTGCTTATGAAAA AAGCGCTGGATAACGCACGAACAGAAAATGACCAAGACCCCTTTCCGAAA GCTTTTGAAGATTACACCGTGTTAGCTTATACTTATGTCAATGATCAAGG CGAAACCGTGACGATGTGGTTACTTGAAAAAGATGGAAAACGAGTAGAAA ACAAGGAATTACAAGATTTCTTAGAAAAACATGGTCAGGAATTAGACCCA CTTCTTTATACCAACCTTTCTGGAGAAGAACTCGAACGAAAAGTGAATGA TTCTTGGAAAGAGGGTATCAACTATTTAAATGGTCAAAAAGTATCTGGAT TTTCTGGAGCCACACTGCGGTCATCCGCTTATGTGGCTAGTTTGAAAGAT TGGACAGATGATGCTGGGTTGACAGATATGGCATTAGGTTTAGGGTTTGG GATTGCAGCAGCTAGAAATAAAGCGATAATACCTAAGAAATCCAGTGGAC TTAAATTTGACGATATAGAAAAATTGGAAAACCATTTTACAAAACATGGA GGGGAGTTTAAAGGTGCATATTCGAATATAAATGAATATCTAAAAGGGGC GAATAATGTAATTAAGAATGGTGAAAAAGTACAATATAATTATACATTGA AGGATGGAACAACCGAGTTGAGAACTGGCTATGTGAAGTTTATGGGGAAC ACTAGTAAAGGAAAAGCAAAATTTGAATTTGTTGGTACTAACTTATCTGG AGATATTACGACCTACCATGTGAAACGCGGCGAGGATGTATATAAATTAT TGAATGGAAACAAGCATATAAATGTGATAAATCCAATAGAATAG ORF2291 (SEQ ID NO:50) AAATTAACTACGAAAGAAGGAGGGGAGCTGATGAAGAAGTTTTCCATGCG AGTGGTCCTTATTATTTCTGTGCTTTTTATTGCTTTTGGGAGCGCTAATG TTTCTATCGCACAAGAGATGGATACAACGAATAAGCTTCCAGAAGAGGAG CTGGGTTCTCTTTATACCTCTAATCTCATTACAGAAGAAGTCGCGCAAGA CAAACCAGCAGAGGTGGAGCAACTAGAAGAAATTCCAACTACGGATGAGT TGATGCAAAATCCAGATGTTCTGGAACAGCCTGTTGCTGATTCAGATGAT CCGGATTTAACAGTGGTAAGCTCAGGTGCTTACTGGACGATTTATCGCAA TACTGTGAACGGTGAATATAGCTTGCATATGTTTGGCAACGTGCCAAGCA GTAGACCAACCGCTTGGAATAGCTATTTGAAAAGCATTAAACATATAGAG ATTGAAGAAGCTACTTTGACAGGAAATTTTGCATCGTATTTTGACAATAG CGCTTTTCCAGCACTGGAAAGCGTGAGGATTGAACAGTGTAATTTGTCTG GAGTGACGTCTTTTGCTTCTGCATTTTATAGTTCAGGAATTGAAAAAGTT ATTATTAGGGATAATGATTATCCGACAGCACCATCTTTACTCACTACGCA ATCTATGTTTGGTTATGCTAACAAACTTACGGAGCTTGATGTGAGTGGTC TTGATACGAGTGCTGTAACTAATATGCAGAACATGTTTCAGTACTGTAGA GCACTTGAGGAACTGGATGTAAGTCATTTTGATACTAGTTCCGTTACTAC TATGAGGGGCATGTTTCAGTACTGTGAATTACTTGATAAATTGGATGTAA GCAACTGGGATACTAGTTCCGTTACTACTATGATGAGTGCGTTTGCTGAA TGTAACTCACTAGAGATTTTGGATGTAAGTAATTTTGATACCAGTTCAGT AACTGATATGACTGCCATGTTTCAAAACTGTTATGCACTGGAGAAATTGA ATATAAGTAATTTTGATACCAGTTCAGTAACTAAAATGTATGCCATGTTT TCAGGGCTATATGAAGTCGGAAAATTAGATGCAAGTAATTTTGATACTAG TCTGGTTACTACTATGAATAGAATGTTTCAAAATTGCAAGTCACTTAAAG AGCTAGATATAGGCAATTTTAATACGAGTTTAGTAACGGATATGGACCGG ATGTTTATAAATTGTGCAGCGTTAAAATCTTTATATCTGGATAATTTTAC TACCGCAAAGACCATGACAGATATGTTTACTGGAACCACCTCCCTAACCT ACTTGTTTGTCAGTCACAATTTAAGTACTTTTACTGGCCTAGAAAATACA AGCTGGTATGACGAAAAGAATTGGGTACAGTTTTCTAATCTCTCGCAACT ACAGACATATCACCGGAAACAAAGTGAACCTACAGGCTACAGAAAAGGTG AGTTCCTTTCCTTAACGATGGATGCGATGGGTGGAGAATTTGAAGACGCG GAGGAACAAAAAGTACAAAGTAAAATTTCTGGGGAGTACTGGGAAGAAGT GATTCCAGTAAAAGAAGGACATTACTTTGACGGGTGGTATCTTGATCAAA ATTTCACTAATAAGTTTGACTTTTCATTGCCAGCTGCTGTATCTACAACT ATCTACGCAAAATGGATAGAAAACTATACAGTGATTATTCCGGCTTCCAT TTCTTTAAATGAAACTTCTGAATTGAAAGTAGAAGGGATTAATCGAGGAG ATAAAAATTTGTCCGTGGGATTAAACCGAACAGCAACGTCTATTTCTGAA AGCAACAAGCTAACCTTGTCCAATACGGCAGACGCAACAGTCCAATGTTT GGTACCACTAAGTTGGGATGGGTCCGAAAACAATCCAGAAAATGCCATTT TAACTCTCGCTCCAGGTTCGGAAATAACAGAAGGCGATGCAGTTATGGAA ATAAAATCCCCAGAAAATATCCAGGCAGGAAAATATACAGGGAACGTTGT ATTTTCGATTAAGTATGACTGA ORF2293 (SEQ ID NO:51) ATAAATTGGAGGTTACCTATGAAGAAGAAAAGAGTAGTGATCATATCCTT ACTACTATTGTTAGTAAGTGTCATTGGAATCAGTAGTTATTTTCTATTCA AGGATAAAATAAATCTGTTGGATGTAGACCATTCTGCCGTTGATTGGAAC GGGAAAAAACAGAAGGATACAAGTGGAGAAGAAAATACAATCGCCATTCC GGGTTTTGAAAAAGTAACGTTGTATGCAAATGAAACAACACAAGCAGTCA ATTTCCATAATCCGGAAATTAATGATTGTTACTTCAAAATATCGCTTATT CATCCGGATGGTTCGGTTCTATGGATATCCGATTTGATTGAACCGGGAAA AGGTATGTATTCCATTGAATTAGAAAAAACGTTAGCGGTAGGCGAATATG AAAATGCAGTATTAAAATATGAATGTTTTTCTTTAAACGATCAGTCACCT TTAAACGGGTCTGAAATAAATTTAAAATTAGTTGTCGTCTAG ORF2336 (SEQ ID NO:52) AAAGCATACAGCAGAGGTGAAGAGTTGAAAAAAAGATGGATAATAGCACT AGCAATTATAGTAATAACCATTTTTGGTTTAGGGGTGAAATTCTATATGG ATGAGGAGAAATTAAACAAAGAAATGATGAATGTAGTTTATAGTGATGAA GCAAAACAAGTATTCGAAAAAAGGCTGACAAATTTAGATCCAAATGCTTT TACAGAAAAAGGTATAATTCATTCTTATAAAATTGAAGAAGGAAGCGTAG AGCACAACCCAATGGGAGGTATAGAAGTCGGATTAATAATTAATAATGAT TCAGAACTAAATGTATCATATACCTTGAGCAAGAACAATGGAGAGTTAAG TGGTGGTGCTTCAGTTGTATCTGAAAAGCTTTCTAAACTATTAGGTCGTT GGGAGGAGTAG ORF2372 (SEQ ID NO:53) AAGTTAATTTGTCTTATACTTAGTTTATCAGCTGATAATAAATCAAAAGG GGATCGGATAATGGCAAATTTGAAAGTAATAGAAAATGAAGCAACTATTC TAGCTTCTATACCTAAACATAATGTTGATTACAATGCTAGAGTAATGCAA TCTGTTTCTGTTGACTACGAGCGAGATATGATTTACTGGACGCAACAGTA CAGCGGAAAAAAAATGACTGATGCTGGAGCTGGGGAGTCATATAACATTA CGAGGACAGATTTGAAAGGAAATTACATTGATCAAATGTGGTGTTTAAAC GGTGGGCATGGAACAAATATTGCACTTGATTATAATTTAGAAAGTAAAAA AATGCATATTTGGTCGGCATATAAAATTAACAATAAATGGGAAGTGGTTT GTTACCCTTATGAAAGTAATAAAATCCTAAAGGGAACCGAGTCCAGTATT TTCATTTCAAAAGTAGAGAGTGGCAGCTATAACCGAATTTCAGGAGATTT GAAAAACGATATGTTGGTTTTTCATTCAGGTGGAGATCCTAAAACGTTTA ATATTAGAATCGTGCGTGCTTCCTCTGTAAGAGAGGGAAAGCTTGAAGTA CTTTATAAAGTAAAGGCAACTGAAGCAAATGATGCATATGTTTACCAAGG GTGTGCGTTAGATTTTCCATATTTATATACAGCTTCTGGTACTGGTGGCG TTGAAGAACCAAAACAATTAACTTGCGTGGATATAGTAACTGGAAAACGT GTGTATCAAACAACATTTAAGTTCAATACAAAAGCAATGCAAACCACAGA AAGCAATTTTGCAGAACCAGAAAATGTTTGTGTATATTATAAAAATAACC AAAAGCATATTGTAGTAGGATATGCTTTGGGAGGAGCAGGGAATCGTATG AATAGAGCATTTGATCTTGTAGAAAATAATAGTGAAAACATAGAAACAGA AATTGAAAGTTTAAGAAACCTTATTATAAGTAGAAAACGTACAGAAGTTA TTTTTGATCAAAGTACTAAAGGGGATATGACAACAAATTTTAAATTACGT GAAACGTTAAATAATTTTGATATTATCCAAGTTGTCCTTGAATCTGGTGG GGGGTATACAACTGCATCTCGACTCGTATCGCCAAAACTATTCGAGGCAT CTAAATCATTTATTTTTGCTTCGAGTAATATTGGTGATGCTAGTGGAAAT AATGTAGATATGTACGAATACGCTGCTAATTTTAATGATGACTTAACATC TTTTAAGAATGATCGTGCAGTCAAAATCGAAGTTTCAAATAACGGAACAG TACGGGGTAATATTACGAATATGGGTATTAAAAAAATCTATGGTATTGTT TTGTAA ORF2375 (SEQ ID NO:54) AAATTAACTACGAAAGAAGGAGGGGAGCTGATGAAGAAGTTTTCCATGCG AGTGGTCCTTATTATTTCTGTGCTTTTTATTACTTTTGGGAGCGCTAATG TTTCTACCGCACAAGAAAGGGACACAGCAAATAAGCTTCCAGAGGTGGAA CTAGGTTCTCTGGATACCTCTAATATCATTGCAGAAGAAGTTACGCAAGA GAAACCAGCAGAAGTGGAGCAACTAGAAGAAATCCCAACTACGGATGAAT TGATGCAAAATCCAAATGTTCTTGAGAAGTCTGTTGCCGATTCGGATGAT CCGGATTTAACAGTGGTAAGCTCAGGTGCTTACTGGACGATTTATTATAA TTCTGCGAACGGCGAATATAGCTTGCGTATGTTTGGCAACGTACCAAGCA GTAAACCAACCGCTTGGAATAGTTATTTGAGTAACATTAAACATATAGAG ATTGAAGAAGCTACGCTGACAGGAAGTTTTGAAGCTTATTTTAGAGATAA TGTTTTCACGGTACTTGAAAGTGTGAGGATTGAACAGTGTAATTTGTCTG GAGTGACGTCTTTTAGATCCGCATTTGAAGGTCAATTAGCGCTTGAAAAA GTGATCATCAGAGATAATTATTATCCGACAACGCCAACTTTACGCACTAC GGAAAATATGTTTCTGGGATGTTACAACCTTAGGGAGTTTGATGTGAGTG GCCTTGATACTAGAGCAGTAACTAATATGAGGGCCATGTTTCAAAATTGT ACTAGCCTTGAAGAGTTAGATGTAAGTAATTTTGATACAAGTTCAGTTAC AACTATGCAGAATATGTTTCAAAATTGTACTAGCCTTGAAGAGCTAGATG TAAGTAACTTTGACACCCGTTCAGTAACTTCTATGGCTTACATGTTTTAT AGGAGTGCCGGTCTTAAAGAATTAGATGTAAGTAATTTTAATACTAGTTC AGTAACTGCAATACAGGGCATGTTTTATGATTGTTCTAGCCTTGAAGAGC TAGATGTAAGTAATTTTGATACCCGTTCAGTGACTTCTATGACCTTCATG TTTTTGAATTGTGCTAATCTTGAAGAATTAGATGTAAGTAATTTTAATAC CCGTTCAGTAACTTCTATGACTTACATGTTTGGAGGTTGTACCAGTCTTA AAGAATTAGATCTAAGTAATTTTAATACGAGTTCAGTTACAGCTATGTAT AATATGTTTCAAAATAGTACTAGCCTTGAAGAGCTTGATTTAAGTAATTT TAATACGAGTTCAGTAACTAATATGTCTTACATGTTTCAAAATTGTACAG CGTTAAAATCTTTATATCTAGATAATTTCACTACTCCAAAGACTATGACA GATATGTTTATTGGAACCACCTCCTTAACCTACTTGTTTGTCAGTCACAA TTTTAAGGATTTTAATGGGGTAGAAAATACAAACTGGTTTGACGAAAAGA ATGGGGTACAGTTTTCGAATCTCTCGCAACTACAGACATATCATCAACAA CAAAGGGAACCTACTGGCTACAGAAAAGGTGTGTTCCTTTCCTTAACGAT GGATGCGATGGGTGGGCAGTTTGAAGACGCGGAGGAACAAAAGGTACAAA ATAAAGTTTCTGGGGAATACTGGGAAGAAGTGGTTCCTGTAAAAGAAGGA CATTATTTTGATGGGTGGTATCTTGATCGAAACTTCACTAATAAGTTTGA TTTTTCTTTGCCTGTTGCTGTATCTACAACTATCTACGCTAAATGGGTAG AAAATTATACGGTGGTTATTCCAGCTTCTATTTCCTTAAATGAAGCTACT GAATTGAAAGTAGAAGGGATTAATCGAGGGAGTAAAACTTTATCCGTAGG CTTGAATTATGAGGAAACAACCATTTCTGAGAGCAACAAGCTAACCTTGG CCAATACGGCAGACACAACAGTCCAATGTTTGGCACCACTGAGTTGGGAC GGGTCAGAAACTAATCCAGAAAAAGTGATTTTAACCCTTGCCCCAGGTTC GGAAATAACAGAAGGCGATGCAGTCATGGCTATTGAAGCGCCAGAAAACA TCCAGGCAGGAACGTATACCGGGAATCTAGTATTTTCGATTAATTATGAA TAA ORF2440 (SEQ ID NO:55) ATAATATTCCACATCCAATTGCATAACATCTTTTTTTTAATCACATTATT TCCAGGTATGCTTCTTTTATTGACGAAATGGATTCCAGTTCTATCTAGAA AGAGTACTTTTTTTCAATATTTACTTTGTTTATTCTTGATCACAATTATG AATAGTTTGTTTTTCCGTCAACAGTTTGTGGTAGTTTTATCGCTGATATG TATTTTATTCTTACCATTTATTCTGTTTTTTGTAGAATATATATTTGTTG AGAGACAATGGAAAAAGTTGCTTACTATTTATAAAAAAAATAAAATTATT ATCCAATCTATTGTATGGTTTCCTGTTTTAGAAGAAATAATTTTCCGTTT TTTTATTTATCAATACTGTGAGTTATTTGATTTCAGTAATATCCAGTATA TATTACTAGCCACCTTTTCATTTGTGATTGCACATATTTTTTATCAAGGA GTGTCTTCAATTGTCAAAATACTATTTTCTTTTATATTAAGTATATTATT TTTATTAACACTAAATATATTTTTGACAATAATAATTCACTGTATTTTCA ACTTTTTAGTTTATATAGTTCGTACTAGTAAATATGAGAACCACCGTAAT TGGTAA ORF2462 (SEQ ID NO:56) GGGGTTGTAGTGAGAGTGGAAAAGCCATTTTTAACAGTTGTGGTACCTTG TTATAATGAAGAAGAAGTTCTGAGCGAGAGTGTTACACAACTAACAAATA TTATAGAAAAATTAGTGATGAGTGAATCAATCAGTGACAAAAGTCAAATT ATGTTTGTAGATGATGGAAGTAAAGATAGAACTTGGGAACTTATACAGCA ATACTCAGAATCAAATGAACATGTATCTGGACTAAAATTAAGTCGGAATT ATGGACATCAAGGAGCTTTACTTGCTGGCTTAACAGAAGCACATGCATAT TCAGATTGTGTCGTGTCTATTGATGCTGATTTACAAGATGATGTGAATGC GATTATTGAGTTTATAGAAAAATATCATGAAGGTTACGATGTCGTTTATG GCGTACGAGATAAACGTGACACTGACACTTACTTCAAAAGAAATTCAGCG TTAGCTTTCTATAGAATTATGAGCAAACTAGGAGTTAATATGGTTCCAAA TCATGCGGACTATCGACTGCTTAGCAAGCGTGCATTAACAGAATTCTTAC GTTATAAAGAAGAAAACATGTTTATTCGAGGCATTGTACCATTATTAGGT TTCAAATCTACGAAAGTATTTTACAATCGAAATGAGAGATTTGCAGGAGA ATCAAAATATCCACTTAAGAAAATGGTTTTATTTGCTGTGGATGGAATTA CATCTTTCAGTGTTGCACCCATTCGATTATTATTAGTCCTTGGATCTGTT ATTTTTATGATAGGCGTAGTAATGGGGATTTATGCCATTGTTCAAAAAAT CATTGGTGCTGTTGTACCTGGTTGGACATCTTTAATTGTTTCCTTGTGGT TAATTGGCGGAATTCAATTAATTGGTATTGGTGTTCTAGGTGAATACATT GGAAAAATCTTTAAACAAGTAAAAGAACGACCTCGTTTTACTATTGAAGA GAATGTTTTTGAAACAAAATGCAAAGAAAATAAAATCAGCGAGAGATAG ORF2541 (SEQ ID NO:57) ATCAAGTTGCTAAAATACAAGATACAAGGAGTGCTATATTTTTTGAAAAA ATTTGTTTTAATTTTTATTTGTTTTCTCACGCTAACAACCATTGTCCCTT GGAATACGCTCGAAACGAAGGCGGCATCCACTTCTTGGCTTGAACAAGAA TTAGATGGTAATGAAGCCTTTATCACTGAAACAGAAAGAGTCTTGTCAAA AAATCGTGAAGATATTACACTCGCAGATTTAGAAACAATACAAGAATTAG ATATTTATGGTGATGCTTCATCAATACCCGACAAAATTTCTGATTATAAG AATCTCAATACTTTACTTGCCCTTAATGGAACGATTTCAGAAATTCCAAC TAGTATCACTAAACTAACAAAACTAACAAGAATCAACGTAGACAATAATA ATTTTCAAGAATTTCCGATGATTCTATTACAGATGCCTTCTCTAAGTTCT ATTGAGATAAATAGAAATAAAATTAAAGAGATTCCTTCAGAAATAACCAC ATTATCCCCTCATTTAGGATCGCTGGATGTACGCTATAATGAGCTAATTA CGCTTCCGGATAATATCTTCACTACTGAGTGGGAAAGTAAGCTCTCATTA CTAACTACAGGAAATCAATTAGTTTCTGACATTCCTGCTGATTGGTTAGA TAATTTTAATCAAGCAGATAACATGCTCGAATTTTACAACAATCCACCAA ATGATTATCATCAAAAACAAGACCAGCTAACGTATAGTGGAGCAAGAATT GAAGTCCCATTAAATACAGATCTAAAAACATTAACTCCTGATAAAACAAA ACTGGGCTTAAAATCAGGCAGAACGTTATTTGAACAACATGAATTTATGT ATTATGATGACGGGACCTCTAATAACATTCTAACTAACGGTGTTGCTACT GCCACAGGAAATGGCTATATAACAATCAAAAGTACTTTATCAACCAATTC CAACCCTTTTGCAAAAGTACGAGTTCCTATCACAGTAACGCCCCCAGTAA AAGGAGGAGATGTTACCGTTCAATATAAAGACACAACTGGAGTAGTGTTA GCAGACTCCATTACTTTATCCGGAAATGTGGGCGAAAATTATACGACAAC AGCTAAAACAATTGACGGCTATTCTTTAACAACTACACCAACCAATGCTA ATGGAACTTTTTCAACAAACCCACAAACTGTCACATATACTTATAAAAAA GACCCTATAGCGCAACCAGTTACTGTTAATTATATTGATACAGATGGAAA AACAATTGCTCCCACTGAAACATTAAGCGGAAATGTGGGCGAAAATTATA CGACAACTGCTAAAACAATTGACGGCTATTCTTTAACAACTACACCTGCC AATGCTAATGGAACTTTTTCAACAAACCCACAAACTGTCACATATACTTA CACAAAAGATCCTATAGCGCAACCAGTTACTGTTAATTATATCGATACAG ATGGAAAAACAATTGCTCCTTCTGAAACCTTAACCGGAAATATTAGTGAA AACTATACGACAACAGCTAAAACAATTGACGGCTATTCTTTAACAACTAC ACCTGCCAATGCCAAGGGGACTTTTTCGACAGAACCTCAAATAATTAATT ATATCTATGCGAAAAACGCTGAGACAGCCCAACCTATTACCGTTAATTAT AGAAACTCTACAGGTCAAAAAATCGCGAAAAGTGAGGTTTTAACTGGTAA TATCGGAGAATCTTACTCAACTCAACCGAAAACAATTGCTGGTTACACAC TCACAACAATACCTCCAAATGCAAAAGGAACCTTTACAACAAATGCGCAA ACAGTAACTTATATGTATACGCCGATTGCTATTTCCGCCTTACCAGTGAC AGTGAACTATTTAGATGAAAATGGTAAAGAAATTGCTGACTCTGTAGTTC TAAATGGTCGTGTGGGAGAGGCTTATAATACACTAGCTAAAGAAATAGAT GGCTACACGTTGATAAAAACTCCTACAAATTCTAATGGTGTGTTTTCGGC GGAAGCACAATCAATCGATTATATCTACCGTAAAAATAAACCAGTAGTAA TAGTAAATCCACCAATCAAAAACCCGATTATTAAAATAGATTCTAGTACC AACGTAATAAAAGAAGAAACGTCTGTCTTACCAAAAACTGGCGATTCCAA TCCATACAATGACTTTTTGGCAGGAATTCTACTATTATCTTCAGCGATGT TTCTTTGGAAAAATCATAAATAA ORF2568 (SEQ ID NO:58) AATTGTAAAGTTGAAGGGGCAAAAAAAATGAAATTAGGTAAAGTAGGAGC CTTACTTCTCGGTACGGCTTTAGTTTTCCAGGCACCATTCCAAGTTTTCG CAACGAGTGTAAATGGAGAAGAACAGGTGAAAAAAGAAGCTGCTGCGCCA AAAATATCCGTTAACAAGCAAACCTTAGCTGCTACCAGTGATTTAGAACA AACGGTAGGGGAAGCAATTACCAAAACGATACATCTTCAAGATCAAGCAT TACCAAACAATGAATGGGGTAGCTATATTTCTGACGTGAAAGTAACATTA TCCAATATGGACGGAATTAGTTATGACGTGAAATACGGACCGCTAAGTGA AGACGGTACGCACTATCAATATGCAGACATAACACTTTCAGGAGCACCGA CAAAAGCTGGAACAGGAAGCATTAGCCTTGAATATTACGACGGGGCAGGT AACGGTGGAGTTTACAGTTATTCTGTAAACACAAAATCTAAAACAACTAT CCAATATGTAGATGGTGATGGAAATAAGTTAGCAGAGGATACAGTGAAAA CGGGTGATTTAAATACAGCCTATACCTCTGAACCAAAAACGATTGATGGA TATGAAGTAGACGAAACAAAACTTCCTAGCAATCAAAATGGTCAGTTTGC TGAAACAAATCAGACAGTTACGTACATCTACTCAAAAACGAAAAGTGAAG TAAATAAAGGAACGGTCGGTATTTCATTCTATACTCCTGATGGTAGCCGC CGGGAACTTAAGTCCTCATTAGACTTAAGTTATGCCTACCCAGATGGTGT CCCAACAGACACAGTAACATTCGGCGATTTAGCAAAAAATACGACTTACA AAGATTTAAGAAATACGCCTGATGCGCCTACTCTTTTATGGAATGATTTG TTACATTACATGGTAGACTACATGAACGGCGATATAGATGCCGCTCAATT TGAAGAGGCAGTTGGGCTAACACCAGCGAATTTTGATTTAGATTTTATTT CACGAAATTTCGAAGGATATAAATTTGATGAAGCAATGTATCAAGAAAAT CTAAGTAAATTAGTCACTTTTGAGCAAGATGGCGATCAAGTTGATTTGCA AGTACCATTTAAGAAAGTAGAAGTTGGAGCGGATATTACTGTAAAATACG TTGACACAGCAGGAAACGAATTAGCATCTGTAGAAACGTTGAGTGGTGAT GTGGATGATAACTATACTTCAGAAGCAAAAACAATTGATGGTTGGACTTT AAAGGAAACACCTAATAATGCAACAGGAGTCTTTAGTAAAGAGGCACAAA CGGTTACGTATGTTTATGAAAAAAATGATGATACAGATGTCACACCGGCT CCTGACAATTCAGCAGATACAAATGATGACAGTAACTCATCAGATAATAC TGCGACAACAGATGATAATAGTAGTAGCGCAGTGAAAGAAAAGGCGCAAA CACAAGCAAGTAGTCCAAAGGCAGGAAAAGTAACCACACAAGAGAGCACT TCTAACAAAGTAACAGCACAATCAAAAGAATCACTTCCTAAAACGGGAGA TAACGTGTTGGAAAGTAGCTTGTTAGTGGGCTTGGGTATGCTTTTGTTAG GGGGATTATTTGTATTCCTTCGTAAAACTAGAAAAGTAAAATAA ORF2646 (SEQ ID NO:59) GGATGTGGTTTTTTAGTGAAGCGAATACTCATTAGATCGGGTATGCGACC GACCAATGTCTACACGCCGGAAGACATCTATTTAAAGGATCGAACCGGGT TTAACAATGGTAATCTTGCGTATCAATATAGCATTTATCGAGCTTTGTGG AATGATGATGTAGAAATACATGCTGACGGTCTTTCATCTAACCCCAATCT CGCAGAAAAAATCAATGAAAATTACGACCTCTATGTTATGCCTTTAGCTG ACGCATTTCGAGACGACTTTAGGCCAGTACTCCGCAATTACACCCAACTC ATTCGCAAATTAAAAATCCCAGTCATCGTAACAGGCGTCGGGTTAAGAGC GAATTACGAACCACAACTAGACGAAGGTTTTTCTTTTGATGAAGATGTTA CTAACTTTGTTAAAGCAGTCCTAGAAAAATCAGCTCAAATTGGGGTTCGA GGACAAATTACTGCAGATTATTTAAAAAAACTAGGATTTAACGCAGAACT TGACTTCCGAGTAATTGGTTGTCCGTCCCTTTATACATTCGGACGAGAAA TAAAAATAAGAGATTTTCACTTAACAGATCAATCCACCATCGCTATTAAT GCATCCCCAACTTCTTCAGAAATAGCTATCAATTTCCTTAACAACATGAT TACTACATATAAAGACTATCACTTTATCCCTCAACACCTAGACGAATTCC ATTTAATGTATGCCGGCGGTCCAGATATCTCTAGTGATATCAATGGCTAC CCAACAAATATCCAACATAAGTATTATCAAGAAGGTCGAGTAAAATATTT CACTAGCATGCCTAGTTGGTTCGATTTTGTGAAGAAAGTTGATTTTAGCA TTGGCTCTCGCCTACATGGAAACGTCATTCCAACAATAGTCGGAACACCT AATATTTCTTTCGTACAAGATGCCAGAATGCGTGAACTAGCTTCCTACCA TGCGCTTCCTCACGTAACCATCGATGAATTAGAAAAAACCAACAACCTCC AAGAATTACTAACTAAAGTGGACCTGAAATCAGCCGAAAAAGTCCAAGCA AGAAATTTTGATAATTATATTGATTTCTTAGATACTAATGGTCTCAATCA TATCTATAAATACGATAAAAACAGAAAATCAGCTCCCATGGATGAACTTA TAAACTCCATTACTTTCCCAACAAGTCCAGACCCCATTTCCATATTAAAC CCTCAAGAAATGCTAAACCGAGTAAAAATCTCCACCAATTTATTAAAAGA AAGACATGATTTTAGCACAAGATACCGTGTCAATCTCGTAAATAATCAAC TTACCCAACTGAAAAAAACAACTTCTGAACAAAACAAAAAATACCAACAA AAAATTACTGAAACACAAGAAAAAAATCAGCAATTAGAAAAACAACTGAC AGATACTAAACAAAAATTACAGTTGACGATTAATAAAAATCACGAACTAA CTAATAAAATCAGACATTATCAAGGAACATTAAACCGAAAATCTGTAAAA ACTACTTTAAAAGTAGCGAACTCTCTAGCAAATTTAAAAAAGAAAGTCTC CAGAAGCTAA ORF2666 (SEQ ID NO:60) ATGGAAATGAAAAAACTTATTAAATGCACTGCACCAATCTTTATTGCTAC GCTCATTATTTTGCCTGTTTCTCCGTCTATTTCAGCATTGGCGAATGAGA CCTCAGAGATTAGCGAAGGGATTAATGCAACAGAAAAAACAATTGAAACA GAAGAGCTTGTCGTAGAAGAAATTAGTAATGATGAATATCAAGTACTGGA TAAAGAGACAAATGAAACAACTTCAATTGAATTTTCAAAAAATCATATGC AATCTACTATTACAAATCCAGATGGCACTATAGACACAATGATTAAAAAG GATAACTTAATTTACCTAAATGGTGAAGTTATAGGTGAAGAGGTAAAAGA AGAATCGAGACAATTATTAAAAGCCTCTGCTTATAAATATGTTACGACGT TTAAAACAAAAATGTCACTAAAGAAAACAAGTGCATCTATTGCAGTGTCA TTAGCTGGTTTGCTTGGAGGACCCGTTGGAGTATTTAGTACAGTAGCAGG TATGCTACTAACATTGAAATCTTATGCCCCGAGTAAAGAGGTTTATATAA AAATTAAACAATATTATAATAGTTACTCAAGGGAAATAAAAAATGATTAT TCTATTTATAAAAAATCTAACTATACTGGACTGCTTAAGACATTTACACA TAAATATCGTCCGTACGGTTGA ORF2758 (SEQ ID NO:61) CATTGGCTAATGGTTATTGTATTATTATATAATGCCAAAAGAATCGAAAC TGTTTTTTTGTGTTTATTATTAAGCGAAAATGCTGTCGGAAATCAAGCAT TTGCAATCGATTTTGGCAAAATAGAAGACATAGATGTGGCTTTCAAAAAT ACAAAACGGTATAAACTTTTTCCGTCTTGTACTGACACTTTTAAGGAAAA TTATTTTCTAGGGAGTTTCAGCAATATGAAATCCGCTTTCTTTTTGTCTA AATAG ORF2759 (SEQ ID NO:62) TTGCAAATTAAAAATAAAGCTATGTTAATTACTTATTCTGATAGTTTAGG GAAAAATATGGAAGAATTATCCAAGGTGATGGAAACTTATTTTGAAGATG CTGTTGGCGGGATTCACTTATTGCCGTTCTTTCCATCCACTGGAGATCGA GGGTTTGCGCCAAGTGATTACACAACAGTAGATAGCGACCTAGGTTCTTG GGAAATAATCGAGAAATTAGGCGAAAAGTATTATTTAATGTTTGATTTTA TGATTAATCACATTTCTCGCGAATCACTCTTCTTTCAAGATTTTAAAAAA GAGCATTTAAACTCAAAGTATAAAGATATGTTTATTCGTATCAATGATTT CTTTCCTCCGGGTAGACCAAATGAAAAAGACTTAGATTTAATTTATAAGA GAAAAGATAAGGCGCCTTTTCAAGAAGTTGAATTTGCTGATGGGGAAACG GAATTAGTTTGGAATACTTTTGGGGAAGAACAAATTGATTTAGATGTGAC AGCCGAAGTTACAAAAGAATTTATTCGTCAAACGATAAAAAATATGGCTG CACATGGTTGTTCTATTTTGCGTCTTGATGCCTTTGCTTATGCAATTAAA AAATTAGATACAAATGATTTTTTTGTAGAACCGGAAATTTGGGATTTACT GGATGAAGTGAAAGCAGAAGCGGCCAAATATGACATGGAATTATTACCAG AAATTCATGAACATTATTCCATCCAAATGAAAATCGCGAACCATGATTAT TATATCTATGATTTTGCGTTACCCATGGTGATGCTGTACTCGTTATATAG TGGCCGAGTGGAACGTTTAGCTAACTGGTTAGAAATGAGTCCGATGAAGC AATTTACTACTTTAGATACGCATGATGGCATTGGCGTTGTGGATGCACGC GATTTATTAACAGATGAGGAACTCGATTATACTTCAGCAGAATTATACAA AATAGGAGCTAATGTTAAAAAGATATATTCCTCTGAAAAATATAATAACC TGGATATTTATCAAATTAATAGTACCTATTATAGTGCTTTGGGTGACGAT GATAAAAGTTACTTGTTAGCGAGAGTAATTCAATGTTTTGCGCCGGGGAT TCCGCAAATTTATTATGTTGGTTTACTTGCTGGCAAAAATGATATTGACC TTTTAGAGGAAACAAAAGAAGGGCGTAATATTAATCGTCATTACTACACA ATAGATGAAATTAAAAATGAAGTAAAAAGACCAGTTGTTAAAGCGTTGTG CAATTTACTGAGGTTTAGAAATACTTCTGAAGCGTTTGATTTGGAAGGAA GTATAGAAATTGAGACACCTAGCTCAAATGAAATCGTTATTATTCGCAAA AACAAAACAAATAAAATTACAGCGACATTAAAAGCAAATTTAAGTACTAA AACATTCCAAATCAGCGAAAATGAAAGAAATATTTTAATTTAA ORF2763 (SEQ ID NO:63) TTGAAGAAGATTTTACATATTGTTATCGCACTTAGTGTAATTTGTTCGAT AATTTTAGTGCCAGTAGATTGGTCCGCAAAAGCAGGCGGTAATAATAAGC GAGATGATCTTATTAAATCTGTCAGTTTTTATAATTCAAATGGACAAAAT GTAACGGCGAAGGAAAACTATAATGAAAAACTAAATTATTTTTTAGAAGT AGCTTTTGGAGGGAATTCTTTCCAAAAAGGGGACTATTTTAATATTACTT TATCATCTGATGCCTTACTCTATACAGAGAAAGCCTATGATTTGAAAGTG GATATTGACCCAACAGCGGTAACTAATGAACAAGTAGTTGGTAAAGTTAC TGTAGAAAAAATTAATGGATCACCAACATTGCACTTTGTTTTTACAGAAG ATTCAGAGTCTTTTTTTATAAACAGCTTTGATGCGAGTTTTAAAATACAG GTGATGCCAGCGCATGGCGATAAAAACGTTATTAATCTTTCCTATAGTGG CGCTGCAAAAAACTTTAAAAACATTGGGACGAGCAGTGTGGAATGGAACG TAAATATGGCAGATGACTGGCCGCCAGTTGGAATTAGCGATTTTTCTAAA ATAAGTGGCGATTTATACCATGCGATTTTAGTGTATGAAAAGCCGAGTAG TAAAGTGAATTACGAAACAGAAATTTTGGTATCGTATCCGCTTTTTGAAA AACGAATTCCACTTGGAAATGTGCAAAATATTAAAATTGAAGTTTGGGAT GAAGCGAAGGAGATTTATAGAGTTGGTGTAGCCGGGGTGGATTACGGAAC GATTACATACGATGTTGGAACTCCATTTGTAGGCGGTCCTATTTTCCAAA TGAATTGTACTATTCCGTTCAAAGGGATTTCTACTAAAACTCGTGTTAGT TTTGATATTGATACGAATGTGGACGGGAAACCTGGAACAACAGATCCGTA CTTAGTTAGTCTTTCTTCCGTATCATCAGCTACAAAGTCGCTGGAATTCT ATCCAGTGAATAACGCTGATACGAAAATGACAGCTGCTTTTTTTGGGAAA GTAACGACGCGCTTTGAGGATGAGTTAGGCAATCCAGTTACTTTTGATAA TTATAGTACTGTAACAACACCAGGGAAAGTCAATCAAGATGGTAAATTTG AAATAGCGGAACCTTTTTTACACAATTCCGTCCAAAACGTGGATAAACAC GCCTATGATACCCTTTTGGATACTAATAAATATAAATTATTAGAGGTAAC TTCTCCTAATAAACTATCTGAAACAGCGGATAATTTAAGTATTCAAATAA AGCGTGGTTATCAGAATGATGTTTTATACAAAATAAAAGCTCTCCAAAAA CCTGTCATTAGCGCGCTTCCTGAAATCGAATATAGTAAAACAGTGAATAG GACCATGGAAGAGTTTTTGGAAGATGTGGAAGCAAAAACAGATATTCCAG CTGATATAGACTGTGATTTAACGAATGTGAAATGGGGTGTTCCGGGGGAT TACCTAGTTCTTATAACCGCGGTGAATGAGGATAATCAAGCAGCGGATCC TGTTCCTGTAACGATTAAAATTTCCAAAAATCCCGCACCAGTCATAACGG TAGACCCGGAAATAATCTACGATAAAACAGTGACGAAAGAGGAGAGCACA TTACTAAATGAAGTAAATGCGCGAACAAATGACGGTTCGACGATAACTTC TAACATTAACGACAAAGTAAAATGGGGCGTGCCAGGCGATTACGAGGTTA CTTTGAACGCGGTAAATGAAGACGGCGTGGCAGCGGAATCGAAAACATTT ATCGTCCGCATTTTAAAAAGCCCAGCACCAATAATCACGGTAGATCCTGA AATAACCTATCCGAAAACAATAACTAAAACGGAAGCTGAACTCCTTCAAG AAGTAAATGCGCAAACAAATGATGGTTCACCGCTTGTTTCTGATATGAAT GACAAAGTAAAATGGGGCGTGCCAGGCGATTATGAAGTTACGTTAAACGC GATAAATGAAGACGGCGTAGCAGCGGAAGCGAAAACATTTATCGTCCGCA TTTTAAAAAGTCCAGCACCAATAATCACGGTAGATCCTGAAATAACGTAT GATTCTTCTGTAATAAAAGACGAAAGAGAGCTATTAAAAGATGTCCATGC TCGTTCAAGTGACGGTTCGGTAATAACTTCTGATAGTCAGGTAAAAGTAA AATGGAAAAAAACAGGAAGCTATACCGTTACTTTAAATGCAGTAAATGAA GATGGCATTTCTGCTAATTCTGTGCAATTCACTGTGCATATAGTAGACGC TAAAGCAATACCAGTAGTAATTGAAGAAAAGCCTGAATCCACTCCAAAAC CAGATACTAAAGAAAAAGTAGTTATTAAGAAAGAAAAACTACCAAAAACA GGAGATACGAATACAAAAACTATATTGAGTGGGATTTTTTGTTTAGGCGC TTGGTATTTGCTTAGAAGAAAATAG ORF2777 (SEQ ID NO:64) CGAAACGGAGTACATAAAATGAAAAATCAGTTTACCTACTTAATTAACAA TAAAACTACTCAAGGGATGTTCATTTTAATCTTATTTATACCTTGTATTG AAATCGTTCAATTATACATAATGTTAAAGCCAGATGCAGTTAATATTCAT CCTGCTTTTGCATTTTTTCTTGCAGGTTCAAGCCGAGGTCATATCACTCA AATATTATTACTTTGGTTCTTAACTGTTTTAAGTCTGTTACTCGGAGCAG ACTCGCCCATTCAGGAATATCAGACAGGAGTTCGTAATATTATTATTAAT AAAATAGGGAAAAAAGCTTATATTCTTCAAAAATTAGCTGTAAGTTTTAT TCTTTGTTTTATCACCATGCTTACAACTTTATTATTAAATTTTATTTTAG TTTCTATTGTATTCTTAGGTGGCACTTATAAAATGGGGTTAAATGGATTA GGATCGCTTAATACTCTATTTGATTTTAGCATTCAAAACCCCTACTTAGC AGATTTTGGTTTTGGATTTATGGCTTGCTTAATGGCCGGAATGGCTGGAC TTATCGCTACTAGCTCCAGTCTGTTCTTTTTGAATAAAAAATTTGCGTAT CCAGCTGCATTTTTTATTTGGTTTCTGATGATACTTCCAAACAATTCAAT TATGTTTATTTTCCAACCTTTTACAGAATATGGCTTTGAAATAATTTTGC CTATTTTTCTAGTTTTCAGTTTAATAGTTTTGATAATTGTTGGTGTCCTT TACTTATATGAGGTGAAATATGTTAAAGAGTAG ORF2778 (SEQ ID NO:65) AATATGTTAAAGAGTAGATATTTTCTTCTAATTTTTTCCATGTTCCTCTT TTTTTCTGTTTTTTGGTTCACACAAAACATGGAGTACCTAAGTTTCCCTA AAAACAGAGAACTTGTTCTCATTATGAATGGTAGTTTGTATGGGTATATC TCAATCAAATCCCTTTGCTTGATGCTTGTTTTCCCGTATCTTATCTTTTT ACTACTATTTTCAAAAAAAGAACAAATTGTTGCTTTAGCTAGAGAAAAAA ACCGTTTACGATTCTATCATAAAATATTGAAAGATACAGTTATTGCAACA GTACTATTTGTAGGTTTATATCTTAGCGTAAATTTGCTATATTCTTTCAT TTTTCTAAGTAATAAATTGCTCACTGCTACTCATTTTTATAGTGGAATTT TTTTTACTTCTTGCTACTTGTTCTCTTTTATTTAG ORF2779 (SEQ ID NO:66) TGGAATTTTTTTTACTTCTTGCTACTTGTTCTCTTTTATTTAGCTATTGG TTTTCTTTTCAGAATTATATATGACTTAACTACTTCAACTGGCCAAGCGC TTATCTTTGGAGCTTTCGTGATATGCATTGTTTATCTTATTGATTGGATA ATTTTAGAAGGTATATACTGGACACCTCTTCACAATTTAAATTTCTTTGA TCTTTGGTTACAAAATGGTTCTATTAGTTCTGATATACCGTTCATTCTAA TTCCAAACGCCGCGGTAGCATTTATCCTATACTTGATTAGTTCTAATACC TTTATAAAAAAGGATTTTTACTAG ORF2780 (SEQ ID NO:67) AAAAGGATTTTTACTAGTATGAAGAATAATAAACTTATCATTTTAGTAGT TATTTGTTTGTTTCTACAAGCAATATTATTCATGGCCTTTGACTTCCCGT TCAAAACATTACCAATACTAGATGGATTTCCAGTAGGATTAGCCACACCG GTAGTAACCAGATTATTGCTTTACTGGTATCTCCCGATTATTGCTTTTAG TTTCTATATTTCAGGTAATTTAAAAGATTTATTATCTAGTTATGGTTTTT TACAAATTTCTCGAAACTATAAAAAAGAATATTGGCTAATGAAGCAATTT TTAAAACTGTTAATAAAAGTTATTCTTTTTACCAGTTTACAACTCGCTTT AATTTTTATATTCACGCCCTATTCTATATATTCTACTGCTCCTTTTTTAT ACTTAATACTTGGATATTCCATTATGCTATTTACTATTTTTAGTTTGCAA TACCTTTTAGAGCTATTTATAGATGCGCAAAAAGCTTTATTACTTATAAA TGGATATGTAATTATTTCTATTCTTATGGCAGATTTAATCTATCAAAACA CAACAGTTACTTGGCCTTATTATTTATTACTTCCTAATTATGGTATGGGC TTTAGAACTGGATTAATTCCGTTTACTAATACATCTACTTTACTAATCTC AGTACCTACCAGTTTAATTATTTTGCTAGTAGTTTTACTTTGCGTGTTTA TAGTCGCTATTAAAAAATTTAAAACAACAGACATTTTATGA ORF2815 (SEQ ID NO:68) AGAGAACAATTGGATATAGAAGATTTTATTGAAATAACAAGAGGTGAAAA CATGAACGAAAAACAAAATGAAATCCCATTTGATTTTTCTTATTATGCTT TACATTTATTAGGTAAAGGGCTTTATAAAAATAGATGGAGTGCAATATCT GAATTAATAGCTAACGGAATAGATGCTCGTGCAACAAAAATAAGTTTATA TATGAATCTAATCGATAAAGAGAAAGCAGTTATAGAAATTTTTGACAATG GGACAGGTATGGACTATGACGATCTTGTTTCGAAGTATGTACATATTGGA AGAAATAAGCGTGATGAAGAATTGGATGATGTTGAAAGAAATGCTCTCAT GGGGCGCAAAGGGATAGGGAAATTAGCAGCACTAAATCTTTCACAAAAAT ATTATTTAATTTCTAAAACAAGAAATGAATCTTCCCTATGGTGTCTGGAT GCGACTGAAGTAAATAAATCTGACACTCCGAAGTTAAAAAGAGTAGAAAG CAAATCAGTAGCATTGGAAAGCATAGAACATTGGAAAGAAAATTCAACTG GTACCATGATAAAATTAACCAATGTTGATATGACTGGCTTTGGAATTCAG AGTATGGAAGGATTAAAATTAAAACTTTCTGATTTCTACTTGTTAAATCA AATGAGCTGCGAAATAGAAGTAGCTTACATTACTACAAAAGAAGAAAAAA ATAACATCAAGTTTAAAAAAGTGGAAAAGAAGGTAGCATTTAAGAATTTT TATGGTTTTTTTGAAAATATGGAAAATGATAAATATAAAGCTTCCCTAGC GGATACAGTTAGATTTCCATCGGTATATGAAACAATTACTGAAAAACCAA GAAAGGTTCTTTACTTTGATAAACAAAATTTTCCGGAAATTAAAGGAAAG AGAAGATTTAAAAATAAAAATGGAACTTTAAGTGAGAAAGAATACGAATT TGAGTTGAAGGGATGGATAGGGATCCATACATCAACAAAAAAAGATGATG CAGAAAGGAATGATATTACTTTCTTTAGAAATAATACCTATACTCCTAAT AAATTGAGACTTTATATACGGGATAAATTGATTGTTGAAGATTTTATGGC CCAGTATATTCGAAGTACTCAAGCAACTTCTGGATATATTGAAGGTGAAA TTAGTTTTGATATTCTTGATGTCAATGACTTAGAAGATATTACAACATCA GATAGACAAGGATTCACTCATGAGGATGATAGAGTTAAGTTGCTAATTGA TATTCTAAAGCCGATAGTAAATTTGCTTATCAGAGAGCGAAATAAAATGG GGGGACAAATAAGAAAAGAAGAAGAAGAGTATCGTGAACAAGAAAGAGAA GAGATTAGGAAACAAAAAGATGTCGAAGCAATAAAAAGAAAAGAAGCCGA GGATCAGAAAGAGGCTGCTGAAAAAGCAAAAGCAAAAGTAAACCAGGAAA ATATGATTTTGAAGAATAGGATTACGCAAAAAGATATACATTTAGGTAGT GAAAAGAAAAGGAACATTTTTTTGAAATCTTCATTATCTGAAGATAAAAA AAGTTTCTCTCAAAAGGCGCATATGATACGAATTAATGTAAAAACAATTG AAAATACTACTTCTTTTTTAGTTAATGAAATTACAAAAGAAAAACCTAAA TTTAATATAATTAAAGAAAAATTGAAAATAATTTCTCATAATACAAACAG AATTAAGAGGATTATTTCGTATGTGGATAGTGCGAAATTTAATATTGATA ATGAAAAAACAGAAGGAGATTTAATAGGCTTTTTCGAGGAATATGTTGTA AACATTGCCAATCAAGAATGGGAAAAACCGCAAGGGAAAGTTGTTAATCC GGGGAAATGTTCCTTAATAAAGGTTTTCTCTCCACAAGATATAGGAGTTC TTATTGATAACTTATTTAGTAACTCAAGTAAAAATAAAGCAAGAAATATA ATTATTTCAATAAAAGAAGATAAAAAATATTGTTATTTGAATTTTAAAGA TGATGGTAATGGATTACCTTCACATATAACGGATACAGCTGAGCTTTTTG AATTTGGAAAAAGCTATACTATTCGAGGGACAGGGGTAGGTTTAGCACAT ATTAAAGATATAGTGAATGATATGGATGGAAAAGTATATATTCCTAAGGA TAATAAAGAAGGGTTTGAAGTAGAGATGAGATTAACAAAATGA ORF2817 (SEQ ID NO:69) ATGAATAAAGAAACCGAACGAAAGCTTGCTGCGTCACTCACTTCTCAATC AATAGAAATATTACCGTTTATTCCGTATTTTTTACAAGATTTTTTTGAAT TGGGTAGTAGTCCGAAAGATATTACTTATTTAATTAAGCAACATATGCCG TTATCAGCTGAAAGTAATTTTTTGGATTTAGCTTGCGGAAAAGGCGCTGT TTCCATTGGTATCGCTAAGGAACTAGGAAATCCTGTCAAAGGAATAGATT TAATTCCGGCATTTATAGAAGAAGCAAAATGCAAAGCGAAAGAAGCGCAA GTAGAGTCACTGTGCCAATTTGAAGTAGGAGATGTAAATAAATCGGTTCA AAACGAAAAAAATTATGATGCCGTTATATTTGGTGCAGCAGCGGATATAC TTGGAAATCCAGCAGAAACGTTGGAAAAATTGCAGGGAACTGTTAAAGAA GGCGGTTATATTATTATAGATGAAGCATATGTGCCTGAATTAGCGCACAA TAACCAGGTGAAGTATCAAAATTATGAATATCTCACTCGAAAGGAATGGC TGAATTTATTTGAACAGAATCAATTACAATTGGTGGAAGAGCTAGAGGGA ACAGCAGAAGTGGATTTTGAACTGGAAAAGCAACACTTATTAGCAAGAGC CAATGAATTAATTCAGCAATATCCAGAGAAAAAAGCCCTTTTTGAAGGAT ACCTTAAGAGCCAATGGAGCGAATACGATGACTTAGAGGAATATCTTATT GCTGTTACCTGGATTTTACATAAAAAGTAA ORF2819 (SEQ ID NO:70) AAGCGATATGCAAGAAATTTTTCAAGGAGGAGCAAAATGCCAAAACTCGT TACGGGATATGAGCGTCAACAAACTAAAAACCTAATTATCGAACATACAA GCCATTTAATTTATATAAAAAAAGGAATTCAAGGTTTTACTGTGGAGGAT ATTACTCGAGCAGCTAGGATTGGAAAGAGAAAATTCTATACGTGTTTTCC CTCCAAAGAAGCATGCCTATTTGAGGTTGTGGAATATTCCTATCAAGCAC AATTAGAGGCATTTAAAAAAATTATGGAGGAGAAAGGTTCGTTAAAAAGC AAGATGACTCGTTTTTTGAAAGAAGTCTATCTTTCGGAAAAGAGTATAAA CAACTACTTTTCACCGGAAGATTTCCACGCAATACTCCAAAAACTCCCTC CAACATATACGGAAAGAGAAGAAAGAATGACAAGTGAAGTCCTGGAAACT GCCATGACGTATATCGATCTTACGAGAGCTCAATGGGAGGCTTTAGTGAT GTTACTAGATTGTTTAACTTACACTGCGACAAGGAGTTATGTAGAAACTG CCAAAAAAGCGAAAGAAGAGACTTTGGATATATTAATACATTCTATAGCT GATTATGTAGAAAAACAGACCCAGTGCTAA ORF2836 (SEQ ID NO:71) GAGGAAAACAGCTTAATGAAATATATGGTGAAATGGAGAGGTTTTTTTAT CGTTGCAATTATTGGTTTACTCGTTTTTCAAAACGTGTCGCCTGTATTAG CAACCATTGTTGATGAAAAAACAACAATGATAACGCTTAAAATAATCAAA GAAGATAAAGATACAAAAGAAAAAATCAATGGTTCTTCTTTTGAAATTAA AAACAAAAAAACTGGAGAAACAAAAGAAGTTTCTATAACTGAACACGGGA CAATTATAGAAAATTCACTTTCAGAAGGAGAATATATTGTTAAGGAAAAG AAGGCTGCTCCAGGATATACTTTAGACGAACAAACTTATAACGTCACTTT AGCTGATAAAGAAGAGGCTATAACTTCTAGTTCAACAAAAAAAGAGGCAG AAAAAACTCCATCTGTTACAGAACAACCCTCTAAAAAAGGGAATCTGAAA GCAGTTATAACAGATAATATTTTTACTGCAGTAAAGGTGGAAAATGGAAC TGGAAATGAACTTGGTGCGACTAACCGTATAAAAAATGGCGGAGCAGTAG TTCTGAAAATGAATTTTACTTTCTCAGGGAAAAACTACAAAGCTGGAGAT ACATTTAAAACGGTTTTACCAGATTCATTCAACTTTGGAACGACTAATTT AACAGGAGATTTCTTACCTTCAACTGAAGCGAAATGGGATTTGAATGCAA GCACACGTGAATTAACCATTACTTTTTTTAAAGATGGTGTGCAAGAAGGT AATTATGATATTGAGCTTAGTACTGCTTTAAAAAGTTTCTCTGAGACAGA AAAAACTAGTCAGGTAGCGGTGTTTAATACAGCGGGTGGTAATACAGTTT ACCAGTTAGAGATTATTCCTGAAGTAGACAAAGCCACACAGGTAATGCTA GAAGCGATGCCGAGTAAAGTCAATCCGGATAAAGCTACTGTGGATGCGAG ATTTAATTTAACTAAAGAAACTAGTGAACTAGGCGAACTTAGACTATCGG ATACTGCTTACGGGGGTTCGACTATTATTAATAGGAATAGTATTAAGGTC TACTCAACAGATATTAGTGCTAAAGGAACATTCATTGGCTCAAAGCAATT ACTTACTGAGAATACAGATTATGAATTGATTTATGCACCTTCAGGATTAA CAATTAAATTAAAAGAAGGTCTAAAAGCAAAAGGGTATCAAGTTACCTAT GAGCGTTCCATTGATAAGACAAATTCGTCTTTGAGTACTATCGGGACTTC AGCAACAACAGTTGGAAGTTCTGGCATGTTATCAAATGGAAGTATGACCA TTTCAGTAACAATAAAAGCATATGATCATTTAATTAAAAAAGCAGTTTAT AACCCTGTAACTCAATGTATTGATTGGACAATTAATGTTAATTATGATTT AGCAAACTTGACTCCTGGTACGGTTTTAACAGATGTATTAACAGACGATA ATGTTAGTTATGTTGCAGATTCTTTGAAGATTAAGCGAGTCACTTTTAAT GAAGAATCAGGAGAAGCAGTAATAGGCGATGATGCGTCTAATGATTGGAC TGTTTCGACTATATCAGACAACGGTAGTTTTAATATGAACTACAAGAAAA CTGATGAAAAAGCATATCAAGTAACGTATTCTACAAAACTAACCGATTTT AGTCCACGAAAAATTAAAAATGAAGTAACGGATGAAAAAGGTGTTAAAGC AACAGAAAACTTTGATTTCAAGCCAGACTTACTAAATAAAGAAGCTGGAG AGATTGATTATTATAATAATACAATGGATTGGACTATTACAGTTAATTCG GAAGGTATTAATATGCAAAACATTAATATCGTTGACGAGTTTTCTACAGG TGTAAAAAGTTTAGTCAGCTACAATGTGTACGCTTATCCTTCTGATTCAG GCTACAAATTATTAACAGAAGGTAGAGACTTTACCATCCAAAAAGACGTC TCGCCAGCTGGGTTTAAAATTAAACTTATCGGTAACTATGCGACAACAGA TAATAAAATTGTTGTGAAAATGAAAACAAAAATTGATTTAACTGATGGAG CAAAAACGCTAGATAATAAAGCCTCGTTTTCATATTTTGACGGTAGTTTA ACCCAGTATTCAGAAACAGTAAAGGCAGAAGCAACACCGGAAACTAGTAT TTTAGCTAACGGTGGGAAGGTCGGTAAATGGAATCCGGCAACTGGTGAAA TAAATTGGATTGTATCTGTCAATGCAATGGGGAAAAAATATGATAAATTG GTTTTAGATGATGAATTTTTAGATGGTACAACCTTTGTTGAAGGATCTTT ACAGTATCGTAATGTAGTTAATTCATCCGAGCTGACCGACTTGAGTATTC CTCTAGAGATAAAAGGGACTTTAGCACAAGTTGGGGATGCTAATTATCCA ACCAAAATAGACACATCAGCCAATAAAATACATTTGGAATTTGGTAATTT AGATACTAATCGTGTATTTGTTAAATATAAAACAAAACCAAAAGATAATT GGTTCTTCTCACAGTGGGTAAACAATAAAGCTATCGTCTCAGATAATGGA GCAGATGAACAAATATACGAGACGAAAGAGTTTGCTTTTTTGCAAAATGA AGTTATTAAGGTAGCTGGAAACATAGATAATGTCTATGGAAATAAAGTGA ACTGGAATATGGAACTCTTGAATATTTCTCCAGAAAGAACACTGTCTAAT CCGGTTATTACCAATCGATTGGAACAAGGAAATACGGGCGCTCAGTTTAT TAAAAATAGTTTTCAGGTAATTAATACAAAAACGAACGAACCGATAAACG AAGAAAATTATGATATTACTTTTGAAGGAAATACCTTTACCATTCAATTT AAAAACTATACTGCAATGGCGCCAATAAAAGTAAGCTACAGCACAATAAG TTTACTTTCAGGACCAATTTCTAACGAAACGACGGTGGAAGCAGAAGATT TTAGTAATGTTCCAATGTTCTTTAAAAAAAGAAATGCAGCAGTATCACCA GTCTTTACAGTGGGATCTGGATCAGGGATTGCAACGATTGGCACGATTAA AATCACAAAAGTGGATGAAGACGATACTACGAAGAAATTAGAAGGCGCAA AATTTCAGCTTTACACACTAGATGGTGAAAAATCTGGACAAGAAATAAAA ACTAATTCAGAAGGTGAAATTCTACTAGATGGTATACAATCTGGGAAGTA TAAATTAGTTGAAACAGAAGCTCCAGAAGGATACAACATTAGCGATGAAT ACAAAGAAGGAAAAGAAATTACTGTTAATTCATCTGGTGAGGAACTTCTT TTAACCATCAAAAATGCTATGAAAAAAGGCAAGGTTATTTTAACGAAAAA GGACAGTGCATCAGATGAAGTATTAGCAGATGCCGAGTTTGAATTACAAA ACGCCGCTGGGTCAAAACTAAAAGAAAAACTAACAACAGCTGCGAGCGGT AATATAGAAATAACCGATTTAGCACCAGGCGACTATAAGTTAATTGAAAC CAAAGCACCAGCTGGTTACCAATTAGACGCGACCCCGGTTCATTTCACAA TTGATTTTAACCAGTCAGAAGCAGCGAAAGTAAGCAAAACCAATACAGCA AAAACAGGCACGGTAGTGCTAACGAAAAAAGATAGCGCAACAAATACCGA GCTAGCTGACGCCACATTTGAGTTGCGAAACGAGGACGGAGCATTAGTCC GCGAGAATCTCGTAACAGATGATAATGGAGAAATTAGCGTAGCTGATTTG GCACCAGGCGACTATAAATTAATTGAAACCAAAGCCCCAACTGGTTACCA ATTAGACGCGGCACCAGTTCATTTCACGATTGATTTTAACCAAACAGAAG CGGCTAATGTAACCAAAACCAACAAGAAAAAAATTGGTACAATTATAGTT AAATTTATAGATGTAGAGGGCAATCAATTAAATGATGAGGAAATGCATAC TGGAAATGTTGATGAAGAATACAATGTGAAAGCTAAAGAAATCGTTGGCT ACACATTAGTTAAAGATTCCGCTAACAAAAAAGGTATGTATAAAGAAACT TCACAAGAAATAACCTTTGTTTATGAGAAAAAGGCAATGCCGATTATTGT GGAACCTACTGAACCATCAAAACCAACAGAACAGCTAACAGAATCAGCTA CAGTAGCAGAGCCAAAACCTATAAAACAAAACTTTAAAACAACAAACAAA TCAACAAATAATAAGAGAAAACTTCCTTCTACAGGAGATGAGTTCCCTTA TACAATGCTATTCATTGGATTGTTTGTTAGTGTTGCTGGAGTATTCTTCT TAAAAAAACCTAAACAAATAAAATAA ORF2847 (SEQ ID NO:72) GTGTCGGACTTGTTGTCCCTTTCCGCTCCAAAAAAAAGGCGTGAATTTAA GATGCTAGATTCAACAAAACTAGATTCAACAAAATTAGATTCAACAAAAT ATAAAACAAAAAATTATTTACACTTTGATTATAGAGTTAAAATTGAAAAT GTAGAAAGCTATGTAACTGATCATTCGAAGATTGGAAATCATAGCTTTTT ACCGTTAATACGTTATGTATCATCTTTTGAAAAAAGAATAGAAGAAAAAA ATCCAGAGTTTGACAACCGGCCAATTAAGACTAAAGATAGAGTAATTATG TATGCTGGACATATGGATAACTTTATTTATAAATATTATGCAGAAGTGTT GAACAAGGATTTTTACAATAAATTTTGTATGGAAAAAGGTATAGATGATT GTGTATCTGCATATCGAAACAATAAAGTGGGGAAATCTAATATTGATTTT GCTGCTGAAATCATTAATCAAATGGTTAATTATAAGGAAGCTTATATATT GGTGGGAGATTTTACTAATTACTTTGATAAAATAAATCACGAATTACTTA AAAAGCATTTAGCAGAAGTGTTAAATCAGCCAAGGCTGTCAAAAGATTGG TTTAATGTGTTTCGATCAATAACTAAATATGGATATTATGAAAAAAGTTT TTTGAATGAGGAATATGGAAGTGATGAAAGTATCAAACGCTCTAATAAAA AAAGTTATTTTGAAAATATTTCTAAATTTAGAGAGTTTCAAAAAAATAAC AAAACTTTATGTAATAAAAATAAATTTGGTATACCTCAAGGAAGTGCTAT CAGCGCAGTATTTGCAAATATATATGCATCGGAATTTGATTTGAAGTTAA AAGAAATTGCCGACGAATTTTCTGGGATATATAGAAGATACTCAGATGAT TTTATACTAGTTATCCCTAAAAGCGATATAGTAAATGAGCAAAAAATTAG AAGGATTGAAACTGATACAAGAAGGGTAGCTTCGGAATATAAAATAGAGT TGCATAAAGATAAAACAGGACTGTATTTATACGAGAATGATAAAATTTTT GACATAATTAGCAATGAAGTAAGCCATTTAGATTATTTAGGTTTCGTTTT TGATGGCACTACAGTTAAAATGAGAGGGAAGAGTCCGTATAAATTTTACC GAAATGCAAAAAAACTTATAACGTTTGCTCAGAAAGTAAAAGTAAAAAAA GAATTGACTGATTTACCTTATAAGAAAAAAATTTATGGATTGTGTACAGA TTTAGGAAAGAATTATAATAATCACGGTAACTTTATTTCATATGCAAAAA GAGCTCAAAAGAAATTTGATGAAATATCTCCAAATACAAATAATTTAATA ATGAATCAACTAAAAAATCGAAAAAAGAAAATCGAAAAGATGCTAGGTTA TAAAATACATACTAAGATTTAA ORF2848 (SEQ ID NO:73) CTATTATGTTATAATATAGACGATAACCCGAAAGGAACCACATGTATGAA ACTTATAATTACCTTAATCATCATCTTATCAAACTGGTTAATTCAAGAAT TGTTAATGATTCTTGAAGTTAACTTAAAGCAATTCTTAACCGACAATGCC GATAAAGTATTACTTGACTGTTTGAAACATCATATTCTGTATTCTAAAAA CACAGGCATGCTTATTCTATCACAAAATAAACATTTTTTAAAGAAAACAA TGTATAACTTCAACTATTTATCCCCTACTTTAAATAAATATTACATTTCC TATACAAAAAGAGCACTTTCTTAA ORF2854 (SEQ ID NO:74) AATATACAATATGATAATAAAAATTTTAAGGAGTTAAAGATGAAATTTTA TATTAAGGAAATTCAGCTAACAGATTCTAACACATGGAAATTACAAGGCT TCTCAGAAGGAAAAATCAATAGTATCCAAGCATACTACAACGAAATCCGA GAATATAAGCACCCTGAACAAAAGTTGAATATTGCTTTTACTCAAGATAA AAATTCATTCACAGCTACTATTTCTGTTGATGAACTTGCTAGTCTTTCTC TACCAAATAACCAGACTGTGTGGAAATTCAAAGTAAATAATGATTATCCA TATACACATTTAATCACAGATGGGCCAATTATAAATAAACCCTTCCAACC AGAGAACTCGCTTTACAAATACCATTTTGATTTTCCTGAAGGTATTTTAA CACTTGTCAGTAAACCTATAGAACTACTAGCTTCGATAGAGGAGTACAAA TTAGATTCTGATGTGATGTCTGGTTCTATTAAAATCAAGTCGCCACTTCC AAGTAACCAATTTAATGCAAAGCTAATTTTCAAACGTAGACCTACACCAA GCTTTTATTTATTTCACGAGCAACAACAATCATTTGATTTAGGGCTTATT ACTGAAAATATCGTTAATTTTTCTATTCCCACCAAAGATTTATCTACAGC TTTCTTAGTAGACAATACAAATATACTAGATGCCATAATCGAAGTATCAT CTAGTCATAACAAAACAGGCTTATCTGCATTCATATCCATTGATGCAGAT ATGAAGCCAGCTATTCCTAGAGAAATTAAAATAGCAGCGCCACTTTTTGC AACTCTGCGCTCCTATATTACAGGCTCTAACAGATTATCATTCTATTTCA AAAAAAATATTCAGGGGTTAGTGAGTCTGAGTCAATTAAAAGAAACTAAA AAAGATTTGACACTGCAATTCAAATTAGAAAACAGTATCTCTGAAGGTCA AATAGTAGCTAAACGTGCAGATAAAAAAGCGAATACATTTGAATATAATG TAGAACAAGTATGGCCTTTAAAGAAAGGGATTACTAAATATACTGCTCAA ATTAATAAAAATGAATTCTTATCCGGACCAATCAATAGAGCTGATGCGAC ATGGGATTTCTTCCTTCGTTTGGCAAACATGCCAGATTTACCTATTTTAG CGCCAAATACTATTGACTTTAGTTCTTCGGGATTTTTCAATGTTGCTAAT AACGAATTTATGGCGCAATTAACAAGAAACGACTCCAATAATTTAGCTTG TCTTACAGCCGTTGCTCCTAAAATCAAACAAGATATAACAAAAATAGCTG TAATGGGAACTTGTTTTAGCCGAAATGCTTTTAACTCATCTCCATTCTTT AATCCAGATTATAAAGCTTTTTTTGAATGCAGTTTTACGCAGTTTCATTC TTCTATAATTAGTATAATGACCGAACCCGCTAACTTAATTAATCTAGATA AGTATACTGATATTAAAAAAAGCGAGAAACCTTTTATAGAAGATGATTGG AAAAAAGATTTCTTTACTAACCTGAAAAATTCTGACGCTGATTATTTCTT AATTGACCTATATCCTGATGTTATTCGACCAGTTATTTGGTTAAATAATA ATTCAGCTATTACATTATCTTATGTTATAGAACAAAGCCAATTACTTAAT GACATTTCTTACGAGAGAATTTTAGATCATATTGATAATGAAACCTACTT CAATGAGTGGAAAGGCTATGCTGATCAATTTATCGAAAAACTTACAGAAA TAATTCCTACTGATCGGGTTATTTTAAACCTAGGTGGATTTACAACGTCT TATTATGATGAAGATGGAGAAGTCGCAACTTACAAAAACAAAATGGCCAT CGAAAAGAATAATTACTTCTGGGAACGTTTAAATAATTATTTCTTATCTA AATTGCCTGAAGCAAAAGTAATCGACTTTTCGAAAAAAGGCTATATAGGT GATTTCAACTATCCATTTGGGCATTCCTTTTCTCACTTCGAATCCCCTTA TTATAAAGACTTCTTGAAGGAACTTATTTACATCACTAAATCTTAA ORF2884 (SEQ ID NO:75) AGTAAATTGAAAATGGGAGTTGAATACTTATTGGCTTTTATCAGAAAAAA TAGCTTTCTACTGTTTTTAATATTATTTCTCATGAGTTCTATTTTAATTC ATATGTTTTTTTATAATTTTCTCACAGATATTATTGTAACTGTGTTTTTG GGATTAGAAACCATTTTTATTGTCATTATCTCACTAGAAATTATGGATGT TAAAAAGATAAGAAAGCGGACAAAAAGAATTATAGAAATATATTTTTTAA CCTTACTTGGTATAACAGTAATCACGTCATATTTATTTTATTAA ORF2885 (SEQ ID NO:76) ACATTACAGGAGACAATCATGATTGAATTTATTATCGATGTATCAATAAA TTTTATTACATTTGCAATTTGTTTCATTCCGCTGCTTCTCTCAGAAAAAA CTAAAGGTATCTTGGAAATCGTAGGTGCAAGCATACTTTTTGCGGGGATT ATGATAGTTGGAACAGGTATTTTCATAAGCAGTAGCGAAACCCTGAAATC ATATATTTATGTGATTTTGGTAGTGCAAATAATTATTTTGTGCAGCGAAC TCATATTAGTTTTATGGAGTAAAAGTAAAGGAAAGTCTACAATTTTATCT ATCCTATCAGCAATATTAGGTATAGTCGCTTTAGGAATATATATTTATTA TGTTATAGCAAGTTTTATTTATTGA ORF2886 (SEQ ID NO:77) AAACAATTTGAAATTGCTGCTGATTATGTATACCAAAGTAAAGAGATAAT CTTTATTGACATCATAGGCGACGAGACGCCAGCAATTGGAATAATCGCTG AAAATGACTATGAAGGATTAGAAATTACTTTAGTGGATGACGAAGGTCGA TTAGATGGAACTTGTTGGATAAAAAAAGAAGATATTCTAGCCCTGCGTTT CGGCGGCAGTGTAGAACAAGATTTGATGAACAAACTAAAAAAATAA ORF2887 (SEQ ID NO:78) AAAAGGGAGGCTATTCGCTTTAGATTACGGAAAAGTTGGTGGAAATCAAA AAAAATATTTACATGTCCACTGGAACTACAAACCAAAGCACTATATAATC TATCCAAGAAAAGGAAGGGGAAAATAATGCTTGACAAACAACAACTATAT ATTGTAGAAAACAAAGACATACCTAATTATGAAGTTGACTCTGGAATTAC TGGAGCAGAACAAAATTATATTTATAATTTTAAAAATCCAATCCCTATTT CTGAACAAGAATTACAAGACATTTGTGATACTTTTGGTGAGTTTATGGTT TCTGCTTATTTTTTAGTGGATATATTTGGGCCGTATGAGGAATTACCTGG AGACAAAAAGAATGGCTATAAAAAAGTTGTTCTTGCAGATGAATCTATGG AGATAAAGAAAAAGATGTTTCATTTGTTTTTAGAAGGTGATGCTTATCCA GACGCAAACAAAATATTTTTGTTCAAGGAGAAAAAAGAATTAAATGCTAG AAAAAACATGGAAATAGAAGATGGAATGATAGTGATTTCTCCTGTTTTAG ATGTTACTGCTATAGGCATATTTTCAAAAGGAATAGATTTGGCGCAGTTT TTCAAGTAA ORF29 (SEQ ID NO:79) GGGGGCTTTTCTGTGTTACAAAGAAGATTTTGGGGTATTTTTTGTTTTGC CATATTCTTGTTTTTATTTCCAACTATTGGTTCTGCCGAAACATCTGGTG ACTATGAATATACAATAAATGGAAATGAAGCTACCATTACTGATTATACA GGACAGTCTACTGATATTACCATTCCTACAACACTTGGTACTAATAATGA ATATACCGTTACTGCTATCGGGAATGGCGCATTCAAATCCAAGAGATTAA CTAATGTAACGATTCCTAATACAGTTATAACTATTGGCGATGGTGCTTTT ACCATCAATTCACTTGAACAACTAGTCTTACCCAACTCAGTGCAGACTAT AGGGAGGAACTCTTTTAGTGTCAATAAATTAGAAAAAATAACTTATTCTA CTGCTTTAAAAAATATTCCTTCCCAAGCATTTTTAGCTAATAATTTAAAA ACAGTGACTACACCAGCCACTGTTGAAAGTATTGATGCTTCTGCCTTTGA AAATAATTTTATTACTAATATTACAATTCAAAACCCAAATCTTCAAATGG CTTATCAAGCTTTTGCCGCTCAAACAGTTTTAAGTACACTCATTGTACCA AGCAACCACATCCTACCTATAGAAAATTACATTCAGTTTCAAGATGCTTC GGCTCATTTGACTACAGATAATTTATTCATAACTGATTTAGCGAATGGTA TTACGTATAATCAAGCCGAAAAAGCATTAAACTTTTCAGCAGAGCCACTC GAATCTACTTTTTCACTTTTCACTGGGACAAATCGATTTGATTCTTACTA TGATATTTCTGAATATGGTCCTTCTGGAAAGCCATTTATCTACTTCAAGT ATACTAAACCAGTCCTAGTTTCCTATAAAGATGCGTCTGGGAATGAATTA GCTACTTCTACTAGATTAGATGGTAGTATTGGTGAAAATTACGTCACTAC TCCTAAAATAATAGATGGCTATACTTTAAAAGAAACACCCGGAAATGCGA CAGGACAATTTTCTGAAACACTGCAAAATGTAACGTATATTTATGAAAAA ACTGCTGTCCAAAATGGGACAGTCACTGTAAAATATCAAGATGAATCGGG TAAAACACTAGCAAAAGATACTGTTTTAACCGGTGAAGTAAATAATACCT ACCAAACTAAAAGCAAAGACATAGCAGGCTATAAACTTCAAAAAGTGGAA GGAAATGAATCGGGTACTTTTAGCACAACCCCTGCAACTGTTACCTATAT TTATGAAAAAATAGCAAACAGTGATAATACAAATACCAATGGAGAAATGA CCGACAATACTACACTGAGTACTAATGATACTGTGATTTCATCCGAAGCA ACAAAAAAAGTTGATAAAAACACCTCTAATATCCTCCCAACTACTGGTGA TTCAAAAGATGCTCTCTTTTTTGCACTAGGAAGTTTATTGACGTTGTTAT CTACTAGCTTCTTTTTCTTTAAAAGAAGTTAA ORF2925 (SEQ ID NO:80) ACAACAAGATATACAAAAGGAGTTGTTCCAGTGAGCCGAATCGACATCGG AGAAATACAAGATTTTGCATTCCAACTACGCGCAGCCAACCAAACAGGAA GAAAAATCATCCAAGGCGTCAAAACCACCGTGACAAACTACGTAGAAGAT GGTAGTTTAAAAGGGAAGGCCGTGGAAGCGTCCAAAAATTACTTTCAAAT GACATACATTCCACTCTGCGACACGATAATCGAGGCAATGAATGAGAGTG AGGAAAGGTTGAAGCGGTATATCCAAGACTTTCACGACCAAGTAGACCTT TCTCCTAATGCTAAAATTGATGCAGATGGTTTATATGAACTCGGCCAAAT GATTGACCGCATTGAAAGCAAAAAAGAAGCACTGTACCAACGAATGAACA GCAGTACAGAAGGCCAAATGCAAACCTATCGTTCCCAGTTAGCAACCGCA TATAAGCAAGAAAATATTTTAGAGAAATATCTGGCTTTTGAACAAAGTCA TGGGGCTTTTTTCGACCATTTGACGGATTTAGTGCAAGGTATCCAGCAAA CTGTTCGAGAGTTACAATCAAATATCCAGTTTGATAGTCAAACGGGCAGC TATGATTTAAGTAAATTAAATTTTGCCACTGTGAACCGAATGCGAAAAAC GCTAGGAAAAGCGAGTGCCACTGATACGACAGTCTATAATTTTGCGAGTT ATAGCAAAGTAAAACAAGGCGTTATGTGGATTCTTTCAAAAGATGGGAAA GTGGATATTAAAGCAACGGAGGCTTATAATACAGCCAGTTTTAACGGTGA GCTACCAAAAGAAAGTAACCAAGCCACGGAAGAAGGCGAGTTGTTAAAAG CCACACTAGAATCACTGAAGCAAAATAAAGATCCGATAACTGGTCAAGAA ATAATCAAAGCTCAAAGTTTTGGGATTTTAACCTCACTTGTTTTTGGCTA CACGACGAAAGGGTATCAAGGGAAGAAACTGACAATATCGAAAAATACAT TGATAAAATTGAGACAAGCTGATAAAACGGTTATAGAAAGGATTAAGAAA ACTAGCAGAATTGACTATGAAGAAATTGTTAAAAAAGGTAGTAAAATGCC TAAACACATCATCGTGGAAAACAAACAAAGTCTTCCGGGAAAAGCTATGC CCAGTTCCTCGGCTGATTTGTTAAATCCTGATGGAAGTGTAAAACAAAGA AGATATTATGATGAAAAGGGCAGAGCTAAAGAAGATATAGATTTTAACCA TTCAGACGACGGAACTCACGAATTTCCACATAGACATGAGTGGGATTGGG ATAGAAAACCGCCAAGAAAGCCATCTAAATAA ORF2927 (SEQ ID NO:81) GTGGATTCAAACAACGAGAAATTGAAACAACAACTACAAACTCTCCAAAA ACAACAAAAAGATGCGGAATTATCCTTATATATGCTCAAACATGAACAAA ATGAGCGAATTTGGCTAGAAGAAGATTTTGAGCGGATTTGTTACGAAGAA CGCGAGTCTTTGGAGTTGATGAGAGAAGTCTGGCAAGGCGATCAAGCTCG CAATTTCGGCTACTATTTAGAAGACCTCCAAGCAGACGAGAAAAATAAAT GGTGCCAAACCTTTCAAGCTGAGGAAGAAAAACGCCAAGAAAAAATAAAT ACATACCAAAAAAACATCTACCAATTGGAAAGTAAACAACAAGATATACA AAAGGAGTTGTTCCAGTGA ORF2969 (SEQ ID NO:82) TATATAAATCCAATTCGAAAGGGACTCAATAAAATGAATTCAAATGAAAT TTCAGAGATTATAATTCAGCAGAATAAAGGGAAAACAATTATTAAATTGC TTTATACCTTGCCTATATTATTATTTGGAATTTTTATTTTATTTAAAGTA AAAGAATCGTTATTACTAGGTGCTTGTGGAATAATCCTTTTAGTTATCGT GGCACCAACTTATTTTACCGTAGCTAAGCATTTTTTTTCGGGTAAACCAC TGCTTAAAGTGGATCAAGATGGTATTGAGGGATGGAGTAAACGCTTTAAG TGGAATGAAATTGAAAAAGTAGCCTTGCGTAGAGACTGGGGCGCCGTATA TCTGACTGTATATGTACGGAAGAATGGCGGAATTCACAAATATAATATAA ATACAAAAGAAATAGAACGTTCTGCCACAGAATTAATCAAACAAATAGGT TATTTAAAAAACAAATATGAATGA ORF2970 (SEQ ID NO:83) AAATTGGTTAAAAGGATTAGAATAACAATGATTGCCATCACTTTATTTTT ATCGGGATGTGAAAATGGGGATACCGAAAAAACAGATACAGAGGAACAGA CTAAAAACGTTGAAGATGAAGGGGAAAAAGTTGAAATTGAGAGTAATGAA GGGAAGCCACAGCATGAACAGCTTATTAAAATAGAATTGCCTCCTAAAGC AGATTATTTAAATGATGAAACGTTAGAAGTATACAATCAAGCTAAAAAGA AATATGACCAGACAAATCAACTAATTACTAATGATTCAATCACAGTACTG GTAGGAGATTATGGTTACTATGATTCGGTGTGGGGATCATTAGATTGTTC TGCAGTTATTAAAAATGGAACAAACTCAAGCATTAAAGACCTTAGCTTTG AAGTTAGTGTAGAGGATAATGCAATATCTGGAAAGACATTTCTAAATAGT GAAGCACTACCACTTACCAAAACTCAGATAGGAGATTTTGAACCCAATAC GGGAGTGCCAATAGTTATAGCGTTTCCAGAAAAGAACGCGACAGGTGAGG GTGAAGATAAGAAAATTGACACTAAAAATGTAAAGATTCATATTAGTAAT ATTCAATATAAAGTAGAAAAGTAA ORF3102 (SEQ ID NO:84) ATGAGCGGAAAAATAAAATTCAATATCGCCGAAGCTCAAAATATTAGTCT TGAGCTGAAAATTGCAGCAGGTAGGTATACGCAAGAAACAGAAGAGCTAT TAAAAGTGCTGAAAAATAATAGTTTATGTGATAAAGACCAAGATGTCGTT GAACAGAGGGGGCGAATAGAGAAGAATAACCAAAGACTTATAGAATATGA GAAATTTGTAAACACAAATCTCGCTAAATCTAATTCAGTTATAGAAGAAT TGTTTATGAGTGTAGAAGTATTGTATGCACAGCAAGTTTCTGAGTTTAGA AACCCTAATTCTGCGGGTTATAAAGAATTAATGGGAAATGTGAAAGCGAT ATCATATCAAAAAATTTCACAGATTTCAGGATTGGGAGAAATGCTTACAT CGAAAGGTTCGGTGGGAGCAATTAAAGATATCAGAGACACACTACTTGGA ACATTGGTAGATGATACTTACTTGAAATTAATTGATGATACAGTTGAATA TCAAGGAGAAAATAAAAATATAACTGATTTATATGGGGATAAAATATCTA AAGTGGGGTCAAGGAGAAAAAAATTGGACACTCCAACCAAATACCTTTCA ACAGCCTACCTCATCTCAGACACGCTAAAAAGTTTTAACAGTTATGGAAA TAGCAAAGATTCCTCTCGACTTGCAGGAGATCTAACCGGTATAGCAATAA CAAAAGGTGCGGATTTTGCTGTTGGGAAATTAGCTACTACGGCATTATCT GGTTTTGGTGTAAGTGGTGTTAAAGGCGCTATCGCAGGCGCCATTATTTC CGTTGCTGCAGATAAAATTATTGATCCGACGGTTGAATATGTTAAAGAGA GCAAGGTAGAAGCAAAGAGGGATGACTGGGAAACAAAAGGTATATATAAA GGCTGGAAAAAAATTCGAGATTTAAAACTAGAATATACAGTGGGTAACTA TCAAGCAAGTTAA ORF3103 (SEQ ID NO:85) ATAGGAGGGAGAAAGATGGCAAAAGAAATTAAGGTAAATCCAGATTTTTT GAAGAAGGTTGAAAGCAATGTAACAAATTACATTGATGCCCAGAAAGAGG TTTCTGTTGAATTACTAGCAGTTAGGACCAACTTAGCAAGTAATTTTTCA GGTATTGCTTGCGACGAAATAAAAAATTATATAACAGAATTAATGAATGA TCTAGAAAAAGAATTTGGTGTATTTATTACAAAGAATCATGAAAAAGTTA AGGCGTTAGGGGAAAGTTATAAAGAACTTGATGGTCAGTTGGGACAAACC TTTAACTATGGAATGGAGAGGACTAAATGA ORF3132 (SEQ ID NO:86) GCGGTTTTTGTGCAATTTCAAACAGCAAGAACTGTCTTTTTATCTAACAA TTCAATAAAAACCAACCTTCACCCAAAAGGAGCTAACATGAAAAAACTAC AATGGCTAACTAACCGATTATTTGCAACCTCTATCCTCCTAATCACCACG TTATTTATCATACCCCCAACATTTGCGATAGCTGATGGAAGTAAAGTGAG TTTTTATGAATACATATATGGAGCACCTTTTAGATGGCTAACTGTAATTA GTACGACAGATAAGAAAGGTGCATTTACGGAGATGTTTTTCTCGGGAAAC GAGGGTATAACTATCCAATGGCCCAATCTAATGATAAACTTTCTCTTAAT TTTCCTTGCAATAACTATTATCTTTTCCCTAGCAAAAAAGCTTTACGATA AAAAGAACGTCAAAAAAGACAACCCATAA ORF3135 (SEQ ID NO:87) CAAAAAAGGAGACTTATAGTGAAAATAGACTTAGAACAAATATATACTTT ACAATTCACAATGGGATTAAGATACAGACCAATGCAAATCAGGCATAATA TAAAATTATTACTCGTGGCTCTTTTGTTTTTTTCCTGGATTCAAGGCGAC TTTATGAGTGGACTATCAGGCGATTTGAGTATGTTTAGAGTAGACATGTC ATTAATTGTAATTTTAGGAATTTGTTTTATTTTATTAAATCCAATAAAAC TAGCAATAAGGTTTCAGAATTCCAATATTTGTTGTATATTTTTTGTTTTC AATGGTTAA ORF3136 (SEQ ID NO:88) AAGGAGGAAAAAATGTATATTAATTTAAAATCCAGTGATGGAAATGTGAT TACAACAAAAGTTGGTTCTTGCTGGACCTGTGTATTTCTTTCGTTCTTTG GTCCTTTACTCCGAGGAGATATTAAATTCTTCGTTCTTTATGTAATATTA GATGGAGCGGGGCTTTTCATCACTTTGAATTATGATAGAGATATCGGAAT AGCTATCATGGCTATGGTAACTTTACTCTTTGAATCCAATTATAATACAT GGTTTATCCGCGGGAAGATGAATAACGGGTGGGAACCAGAAACAGAGAAA GATCGAGAAATATTGTTAGAAAAAGGCGTCATTAAAACAGAGGTATAG ORF3137 (SEQ ID NO:89) ACTATGAAAAGTAGAAATTGGTTAAAAGGATTGGGAGTAACAATGATTGT CGTTACTTTAATTTTAACGGGATGCGGAAATGGAGACGCTGAAAAGACAG ATACAAAGGAACAGACTAAAAGTGTTGAAGAAGAAGGAAAAGAAGTAAAG ATTGAGAGTAATGAAGGGAAGCCACAGCATGAACAACTTATAACAGTGAA GTTGCCGCCAGAAGCAGAGTATTTAAATGATGAAACGTTAGAAGTGTATG AGCAAGATAAAAAGAAGTATGACCAGACAGAGCAACTAATTACTAATAAC TCAGTTACAATTCTATTAGGTGATTTTTGCTATTATGAGCCGGCATGGAG CAGTCTTACATGTTCTGCAATTCTTGTGAATGGAACTGACACAAATATTG AAGACCTTAGCTTCAAAGCTGAAATAATGAATAAGCCAATGTCAGGAAAA ATTTTTTCAGATGACAAAGTTCCAGAACTTACAAAAGCAAAAACAGGAAA ATTCCAGCCAAACGAGGGTATACCAATTATTTTAGTTTTCTCAGAAGAGA ACCCGAAAAATGAGGAAAATGCGGAGCCTCAAAAAATTAACATTAAGATA TAAAGGTTAAGATAAAGGATATTCAATATAAAGCAGTTAAATAG ORF3138 (SEQ ID NO:90) AATATGGTAAGTCCAATGCCAGATAAAACAGTAAAAATGGATAAAGGAAG TATTAATCCTAAATTAGATAAACTAATTTCAAGTCTAGACAATTTTGATA ATATCAATAAGAAAATGGGCACTATAGTAGGTAGCCAGGAGATTAGTGGG GAAGCAGCAGATGCTTTATCTGAGAGCCTATTAGTGCTAGTAAGTTATGG GGAACAATATAGTTTAGTAATTAGAAACCTAAAAGAAGTGATAGTCGACT ATTGTAAAAGTGTGGAAGAAATTGATAAAACAGCAGCAAACGCAGTAAGT AAAGGCGTTTAA ORF3140 (SEQ ID NO:91) GAGATGATTATCATAAAAAATTTCGCATCAAAAAACATTAGACTAATTAT GGCACTAGTTATTGGAGTATTGGTTTTTGCACCTGTTTTTCATTCAAAAG CCGCTGATAATAACATTGGTTTCGATTTTAAACTCAAACCAAATTGCGCT AACTCAGGGTCAAGCTCAAGGTATAGAGAGACTTCTTCTGTAAATAACCC TTGGAAAGTTCGCCTCGATAACTCAACAGAAGGAAAGGGTACAATTGCTT CTTTTTGGCTAGGTACATATAATAAAAACAAGAATGCTGTACAAGGCTCA ACAATAATGAATGTTAAACAAGGTGCAAAAACACGTTATTGCGGCGCTTA TAAAGTAGCTAATAAAAATACAACCTATTTAGCTGCTGAAAATAATAATT ATAATTCCAAAACATACTATGTCGATGGTATTTGGGATGAGGAAACTTGG TAA ORF3141 (SEQ ID NO:92) TTTGCAAAAAAAATCAAGAGGACGGAAGTGCTTACTAATATTAATTATTC TTTTGAGCCTGGGAAAATCTACGGAGTTTTCGGAAAAAATGGATCTGGAA AAACAATGTTACTTAGATCGCTTGCTGGCTTAATCATACCAACAAGTGGC AAGATATTCATTGATAATAAAGAACTTCATCATGATATTTCTTTTCCGCC AAGTATGGGCATTATTATCGAAAATATGGAATTACTTCCCCAATTTGATG CGCGGACAAATTTAAAAATATTATCTAAAATTAAAAATATTGCAAGCGAT GAAGATATTGATAATGCCATTGATAGAGTAGGATTATCTCCACATATTGA TAAAAAAGTTAAAAAATATTCGCTTGGAATGAAGCAAAGACTTAATATTG CACAGGCCGTTTTTGAAAAACCCGCTGTCATCTTGCTTGATGAACCCACA AATGCGATAGATGATCAAGGTATTGAACTAATTAACCAATTACTTTTAGA AGAAAAGAAACGCGGAGCCACTATTATTATTGCAAGTCATCATAAAGAAG ACATAGAACCACTTTGTGATATGAGTATCCGAATGGACCAAGGGAAAATT ATCCATGACTAA ORF3142 (SEQ ID NO:93) GTATCCGAATGGACCAAGGGAAAATTATCCATGACTAAGACCAAATTCGT TATTTTCATAGCACTGACAGTCATTACACTGCTTCTATTCCTCGTTCCTA AAGGTATTCAATATCTCAAAAGCCAAAATCCTGAGCTATTGAATACAGCT GAAAGCATTAAACTTCAAGCTGGTGAATACACTGTTGGAAAAGATATAAA AGTTGGAATATATGATATGCAAGTAACAAAGGGTTCGCTATCTTACTATA GTACAAGGCTTTCTAAAGGCGATGAAATAATTGGTATTAATTTACTAGAT GCTAATAAACTGTATTTTGAAGGAAGCGGTGAAGTCGAGCTTACACCGGC AGAATTTAATCCCATTAAACCTTCTGCCAATATTTTTACAATCCAACACT CAGGGTCTTACGAAGTTGGTAAACAAATTCCAGCTGGGAAGTACAGCCTG ACTTATACCATTGACAAAAGTAGTAAGAAAAAACCTTTTATTCAAATATT ACCATCTTATACTGATGACGCTCGTATTGAAATACAATTTGAAACCAAAC CGGCATATAATATTAATTTAAAAACAGGAGAAATCTTGACTGTTAGTAAA ACAATATCAGAAGAACTTGATACTATGACCGTCTTACTTAAAAAGAACTA A ORF3144 (SEQ ID NO:94) AAAAACCCTATAAATAATTCTCAAAATTATTCTCAACAATTTGTTAATAT TGATGAAAGTAATTCTGATGATAATTTGGGTAACTACGTTAAAATAAGCC AAGATAACAAACCTATTGGTTGGATAGACTCTGAAAATGTAATTGATGAA AAAACTATGGATTCTATAGAAAATGATGAAGAATCAATTATTCCGGAAGA ATTAATTGATAAAGTAAATGATTATGTAACAATAGAAAACAATGAATTTG TATTGTCTAACAAAGCGGAAGATGTTCTTACTTCGGAAGAGTTTGTTGAA GTTGAAGGGCAGATAGATCGAACTAATGCTGAAATCGAAGCTGATGAAAC ACTATCAGAAACACATATTGAGGGAAACATAATAGTTCAAGAAATCTATG AAGATGAACCAAATCAACTTCTTAAGGCATCTAAAAAAGCTTATATAAAA GCTAAATATACATGGTGGGGTATGCAAATCCAATTTTCTCATAAAGCTGT TGTTGATTTTAACGATTTTTATTGGGGGGCAGGTACGATAGGTGGATTAG GTGCAAATAAACGAATGGGGAAATTTTTAGCAAAAAAAGGAATAAAAATC GCATCACGTTATGCTGTTTGTTTGAGTTTATTTGGTGGTGGTTTAGCATG GGGAATGGGTAAAAAAGATAAAGGAAAAGGTGTAAATTTAAATTGTGTAT TATATGTCCCTGCGACAATAACTACAGCTAAATAA ORF3172 (SEQ ID NO:95) ATGAGTAAAGAAAGATGTGCATGTTGTAACTGCTTAACAATTGATGTTAG AGGCGAGTTTGAGATTTGTCCGATATGTTTCTGGGAAGATGATGCTTATT TTGTCTTTGATAAGGAAGAGATTTATTCTCATTATCAAGGCAGTTCCTCG ATAGAAGATTTGTTAAATATTCGTTCTAGCGCTAACAATAGTTTAACGTT ATTAGAAGCACGGCAAAATTTTAACCAGTTTGGCGCTTGTGAGCTGGCAA TGAAAAAATATGTAAGAGAGCCAACTGCAGAGGAATTATAA ORF3173 (SEQ ID NO:96) AATATAAGTTTATCAAGGAGGAACTCCATGGAAATCACATTACAACAACC TACATCAGCTGACTTTCCCTTCATTGAATGGTTGTGGGGAGATTTGGCAA CGACAGAAATACTCGGTGGACCATTTTCTTTTCCGGAAGAAACGCGAATG GACTGGCTAAAGTCAAAATCACAAGCGAGCAATGCTTATTTTATTATAAA AAAAGGTACAGAATCCGTTGGTGAAGTCAGCTTTCGCGATTTTGAAAAAG GGACAGCTCATTTAAATATTAAAGTGGCTGCATGTTATAGGGGCCAGCGA ATCGCTCAAAAAGCTTTGCAATTATTCTTGGATTTTTTTCAAACTGATTG CGGTGGGCTCGTTTTGTTGGATGAAGTTAGACGGAAAAATGAAGCAGGCA TTAAGTTTCTCGTGAAAGCTGGTTTCGAAGTTATAGAAGAAAAAGAATGG ACGATGGTGCTCAAATGGAGTGCTCAAGCAGAAGGAGGTTTTGAATGA ORF3174 (SEQ ID NO:97) AAAATGAATACTTTGTATTATAGGGTGTCTAAAAATACAAATTTTGAAAC AGCAGCAAGAGAGATTTTTGATTTATTAATAGAAACTCAACAACAATTTG AGAATCAACCGAGATTTTTAAAGGTAGAAATTGATGGACATTTAAATGAG TTAAATGAGTTTGATAATGATATGCTTAAACTTCAACAAGAATTTGGAGA AATTTTTTTACTCCAATTCTTTACCACGATTAGTTTCCCATTGCTTACAA AGAAAAATCCTAGAAAGCAAATAAACGATATACCGAATGACCTAACAATT TATGATTTGAAGTATGGAAATCCAGCATATAAACTTCAAATTGAAAACTA TTATAATACTGAATTTGTTTTAGAAAAAGATGTGTATGTATTCTTGGAAA AAGTTTCTAACCTCCTAAAGAAATATGGAAAAACAGATAACTATAAAATC AATATTGAGAATGAGGAGTATGATAAACTTGGCTTATTGATTCACTGGCA ATCTTATATGAAAGAATTGATAGTAGAACTATTTAATTCTTTTGTAAACG GTAATTTAATTTCGAATGCTGCAATGACTAGGTCACTTATTGAGGGTTAT GTGTATTTAAGTATTATAAAAAAAGAAAGAAATCCATTGTTAGTTCAAGA TTGGTTTCTATGTAACTTAATTATTGGCAGCAAAAGATATGATGATGGCA CTAGAGAAATTTTGAATAATACTTTAAAAGAGCTATTTGACAGTAATGAA GATATACAGTCTAGATATAAAAAAGGGAACACTAATAATTGGCTATCAAC AGTAATTGCTAAGAAAAACATTACATTTAGGGATGCTTGTGAGTATTTGG AAGAAGATTATTTGTACAAAGATTTCCAAGAAGCAAGTTCTTTTGTCCAT GCACAGGATATACAAACCAAATTAAGCCCTTTTTTTTCATACTCCTCGAT ATACGGCAAACTATATATAATGATAATCTATATGTTTAAGACATTATTAC TATTTGAATCATCTTTAGTATTAAAAGAGGAAATTGCTGATTTAGAGCTT GAACTAATAATACTAGGTGAAAATTATTTATAA ORF3175 (SEQ ID NO:98) CTTTATTCTAAAACTATACTCATCTTGCTCATTTTTAAACACAATGTTAT CATTAAATTCAACATAAATTCAACCAAGCAGGTGTGCATCATGATATATT ACAAAGACAAACTTAAAACAATTGGAACAGCTTTAACTTCTTTATCTTTT ATTTTCATGTTTGGCTTATTAACTTTATTGTCAATAGAAAAACCAGAATT ATTTTACTATGGTCTTATTACTATATTTTTTATAGGATATTTAATTGTTA AACTTATACTCCCGCCAAAAGAATGGATCCAGGTCACAAAGACTGCTTTT ATTCTTCATAAACGCAACGAAACAAAAACGATTCATCTTGCAAATGTGAA AAGAATAAGTTATAACTTCCAACCTTCTCGTCCGAGCTTTGGACATCCTA TTCCAGAAACGATGGAACTATTCTTTCATACAGAAAATAAATTAGAAAAA ATTGAATGTGATTTTATCGGCCGTACCAATTTTGTTGCGTTAATTGACCA ATTTGATGCCAAATTAGCCTCATTAAGTGAGGATATAAAAAACCATGACT ATAGCTATCCACGCGATCTTACATTCGGCATTTTTATTTTTAGTATTGTC ATGCTCTTCTTGATTTTCATTCTTTTATTTGGTCGAGAATTTCTATTTGA GCAAATTGGGAAAGTTTTTGTATAG ORF3183 (SEQ ID NO:99) GTTTTCGGCTTTTTTATTATTGGTGCTTTGAAAATATTAAAGCAGATTAG GAGGAATAATATGAAGTCGCAGCAGGCCTTTATGGTAGAGGTTACCTTTT ATTCTAATGCAAGAAAAACGGTTCCGGAAGCGGGGTATCGGCCGCATTTT GTGATGGAGTTGGATGAGAATCGGGAATATTTAGGAGTTGAAATTTATGA TATAGAAGTGGATACGCTAGATTCGGTGGGGTATGCAATGTGTTCTTTTT TATATGAACAAGAGGGCGTTGGTTATAGTAAGATTCAGCCAAATAAGTCT TTTATGGTTATGGAGGGCGCGAGTGTTGTTGGGAGAGGAAAGATAGTGTC GTTTCATTTGTAA ORF3184 (SEQ ID NO:100) GTAGTGATTAGTATACAAAATAATTTGGAATATAACAAGTTACGTTGGGA AACTTTGAGTGGAAATGTAACAGGAATATGGGAGAATAATAAGTTCTTTC TAGGCTCTAGTTCTTACCCTATTATGAAGTATCATTACATTACAGCTAAT TTTGTTAATTTTGAAAAACATATTTCTGAAAATATGCCTAAAATAAGTTA CCATTTAAGTGGATATGGTGTTAATTTTAATGAAGCGCTTGTTAGTTTTA TTGGTGAAAGCGCAGAGCGATATACATATTCCTTACTACCTACTATTATT AAGGACAGGATTATTTTTAGATCATATGAAGAAATGACAAAAGAATATAA AACTGACTTAATATGTGAACTTAAATACATAAATTCGTATTACTCTTCTG AAGTATGCGAAAATTATGTTACTCCAAATGATACTATTCAATGGATAGCA ATGAATTCTCTTGTTCATTCTGATAAAAAAGTATGGATGCCTTTGCAATT TGTTACTATGTATACAGAAGAAATGTTTTCTAATGAAAAAAGATATGTAA CTAGCGCTGTATCAACAGGCACTGCTTGTCATGAAACTGTAGAAAAAAGT ATAGAAAATGCCCTAATTGAATATCTTCAAATTGATTCCTTTAATTTATG GTGGTATGGAGGGTTTCGTGCGAGAGATATAGAAATAGATATCACTCGAA ATATATCAAGCTGGTTCGACAATCAAGTAGCTGTGAAAAAATTTTTATCA AAGTTTAATGTACATTTTTCAGATGTAAGTTTTGATAAATCAATTTATAT TGTGCTATGCGAAATAGAGGCAAAAAATTCAAGTGATGCCTTTCCTAAAT ATACTGTTGGCGTTCAAGGCGGATATTCACTAGATAAATCAATATATCGT GCATTTATGGAATGTCTAACTGTACTAGAATATAATATGAATGTCACTTG GACAGATAAAGAGAAATTTCTTTCAGTCACACAGGAAACACGTGTTATAG ATAATTTGGATGATAATGTTATTTATTATTCAAAGTATGGAAAACCAGAA TTGCAATATAATACTAATCAATTAAAGAATGATACGGAAAAAGTTACAAA TCTGAAGGCACTTTTAGAAAAGTTGCCCACAATTAGTCAGTATGCTGCAT TCTTACCTATCACACCTTCAGAGTTTAGATATATGAATTGTGAAATAAGC AGGGTGATTCTTCCAGAATTGTTATCCATTCATCTTCCTTCATATCCACC TTACTACCATGTAAGATATGAAGAAATTGGAGGTGTGGTAAATAATATTC CACATCCAATTGCATAA ORF3185 (SEQ ID NO:101) ATGATCACATTATATTTTCTAATATTTGTGGAAAGGAATGATATTTTTAT GAAAAATTTTGATATTAGAATAGGAACGCAGACATTTGACAATGATACGG AAATCATTTTAAAAAGAGGGGTCATTCATAAGAACGAGCTCGTTATCAAT AAAGAGGAAAGTTCAAAAGAATTTGTTTCAACTTTTAAAGAATTGATCAA GAAAAAAACTATCGCTATATCTTCAGAAGATGCAATCTACAATGATTTTG AAACACTTACAAAATTTGGTTTTTTGACAATTTCCAAAAACCAAACACTA AAACCTCTTTTGGTAGTTGAAGATGCTTTATTTGATGACATGAAGAGCTA TTTTCAGGAAGAAATTGAGATTTTATCATCCTCTGAATTTCTTTTAAAAA AAGATATTCGGTTACTTACTGAGAACAAAGATATATTGCAACTTACCAAA CTAGTAGATGAAAAAAAAGAATTTTTGAAAAATTATAATTATATTTATTT AATCACAAACATTCCCAATATTTCCTTATTACGTGGATTTAACAAGTTAA TGAAAGAGACTAACTGCATTAATACCATCGCATTTTTTGATAATGAAAAT GTCTTTGTTACTTGTATAGAACATGGCGAAACTGGGTGCTATGAGTGTTT AGAGCAGCAAATACTCTCTCATTTTGATGGTGTTGTTACGGATTATTTAG TACGGTCAGAAAATAATGTTTCCACAGCTGAATTGATGTTTGTTCTTTCA ATCATAAAAAAAGAAATCGAAAATACTTCTATTTATGGTCAATCTTCTCT GTTAGGCAATCTTCTCCACTTTAATTTTAATAATTACGAGTATACGTTTA ATACAAATAGAATCCAAAGTTGTTGCTCTACCTGTGCTACTTTCAATAAT ATATTATTTGAAGAGCAAAATATTCGGTCAGTGAATATACTAAAGGAGCT GATGAGTAGTGATTAG ORF3222 (SEQ ID NO:102) CTAGAGGAGGCGTGTTGGATGGAGAAAGAGCAACAAACGGATGATACTTG GGTTTTAGTTGAAATTGTTAGCCTTATAACCAACGTGGAACGACAAAGAT TGAGAGAACTTAGTTATACAGAGTTAGAAGAATTTTATGAAAGAGTAGTA GTGGAGCAATAA ORF3224 (SEQ ID NO:103) CCCTATTTTCTAATTAAAGATGTAAATAAGGAGGATTTTAAATCCATGAA AAAAATAATCGCGTTAATCACAGCAGTTGCACTTCTATCAATGATTGGAT TTGCCTTTATCCCTGGTACTGTTGCGAATGCAGCGAATTCATCAGAAAGC AGTTTAACATACAAAGATGTACGCAGTGGATTTTACTTTGTTGGTTATGA AAATGTACAACTTGAAACAGGAAAAACATACAAGTACACAGTAGCGTATG AAGCAAATGTTGATATGAAAATGACAGATACTATTACAGGACAATCAGCA AAAGCAGGACTTTTTACACCAAAATCATCCGGTGCCGAGCTGAACACTAG TTACGTAAGCCGAACAAAGAATAACGTTATAGACGTAGCTGATGCAGGTA ATAAGGTTTTTAAACACACATTTGAATTTACAGCGAAGGAAAATACAAAA GCAGATATCGGTGTTTTCTTAGGAGCAGGTTCTGTTCTTCCAACAACTCC AGAAACCACGTCCCTTTGGAAAAACGTAACCGTGACAAATGAAACTCCAC TAGTACAAGCGGAGGCTCCAGTTATTAGTGCAGAAGATAAAACTATCAAT CAAAATGAAAGTTTTAATCCACTAAATGAAGTCACTGCGTCAGACGAAAA AGACGGTGATATTACAAAGGACATCCACGTAACCAAAAATACGGTAGATA CGACTAAGAGTGGCAAATATGATGTGGATTATAGCGTTACAAATTCAAGC AACTTAACAACGACAAAAAGTATTAAAGTAACCGTAACCCCAGCAGCAAT AAGCAAAAATACAGCCCCAGTTATTAATGCAAAAGATCAAACAATCAAAG TTGGAGATGTGTTTAATGTGTTAAAAGGAGTTACTGCGAAAGATAACGAA GATGGTGATTTAACAGCAAAAATCAAAGTGACCAAGGATACAGTGAATAA TTCGAAAAAAGGTGTTTATCAAGTTACATATACTGTGACAGATTCTGGCA ATCTATCAGCTTCACTTACAATTAAAGTGACTGTAACTCAAGATGGAAAA CTAATAGTAAATCCAAGTGATCCAACAAAGCCATCTATCACAAAAACACC TGTGGAACCAACAAAAATTGAAAAAGATCCTGAAAATAGAGCGACTTCCG TTTTGAAAGCAAGTAAAATACCAAAAACTGGTGATAGTTCAATGATATGG CTAGTATTTGTCGGACTCGGCTTAACAGCTATTGGTATTAGTTCTTATCA AAAAAAAGCAAATAAATAA ORF3277 (SEQ ID NO:104) GTTGGTTACTTACAGAGAAAAAAGATATGTTTCGAACCTCGAAAAAGAAG GTGCGTTAATATGTGGTTATTTTTTAAACGGGATATATTATGGTTCCTTC AAGGGAATAAATGGAAAATAATAGGCTTGGGAATGCTTTTGATATTAGCA ATTTTAATAAATGTTGTTAATGCAAAAAATGCATCGGGGACGATAGCAGA TGTGTTTTTGAGCTTTTTAAAACAGGATAATGGGGCGGAAAATCCACTCA CAAGTAGCTTGAATTGGATTATCATTCAAAGTTTGCCAGTTTTTCTATTT GGAAGTTATTTTTACAAGGAATTGTTTGCATTAGAGGAATTTATTACTAT TCGCTTTAATAATAGAATGCTGCCCTTTCTTTCCAAAATTTTACTCATAA TTACGCTGATGTTGATTTATTATTTTGTAATTATTGGGCTAGTAGTGTTT ATTAGTTTTCTTTTTGGTATTCGTTTTGATGTACAACCGACGCTATTATT TATAGATTTAAATATGCCACTTTATGAAATGGGTTTGCACTTTTTTGTTG GAGGGCTGGCACTTATCATGCTTCAATTGTTGCTTTCTATAATAATTAAA CCATTTTATGCAATTACGGTAGTACTTATCATTATTGTGACCAATTGCTT TATTACAAACTTTTGGATTATCGGAAGCGTTTCGAATGTTGCTGGATTCG CTGAGGCAAATAATTGGCTGTTATTAAGTATTCAATTGGTATATATTATT TTGGTGATGCTCATTGGCGGAAATATTTATCGAAAGACAGATTTATATAA ACTAAACTAG ORF3278 (SEQ ID NO:105) AAAATGAAAAATCATAATTTGGTCCGGTTAAATTTTGATTTTGAAAGAAG AAAATATTTAATGCTTCTATTGATATTTGTGTTTATAATAGTATCACGCT TGTTGTACACCAGAAATGTCGAGACAGATGCCCTTTACATTGTACAGAGT TCCGTATCAGTTGAAGTTCTATTTATAATTTTGAGCCCGTTCTGTTTATG GATGAATCAAATATTGTGTTTTCAACGCAGGGAACTAGCTGTTGTTCGGA TTAAGAACAAATATACACTTTGGAAAGTCAATGCAACTGTTATTTTGTGG AATGCCTTTTTGCTTGCAGTATTAACTAATGCCTTAAATTATGCAAATGG TGTTATTGTAATGAATTCCCAAATAGTACAAATTTACATTTATTCTTTTA TATTATTTGGTTTAGGTTTAGTTCTTGTAGGTGTTTTACAGAATATACTA CTTGTAATTACAAGTAATAAGGCAATTGCTTTTTTTGTAGTATTTCTGGT ATTTTTCTTTGATACTAGCACAATCAAATTGCAGCTAATTTCCAATCTGT TTATAGTGAACCCTAATGATCTTACTGACTTGTTGTCATTTGCTGGGCGA GTTTTCTGCTTGGTTGGTGGGATTATTGTATTATTTTTAATAAGTTGGTT ACTTACAGAGAAAAAAGATATGTTTCGAACCTCGAAAAAGAAGGTGCGTT AA ORF3279 (SEQ ID NO:106) ATGAGTCGATTTTTAAAAATAGAATTTAACCGAGTTTTTAAAAGTAAATC ATTTCTTGCTGCTCTTGCACTGGGAGTGTTAATTGTACTAATTCAACAAA TAACTGTCGCACGTTACTATTCCACGGCAGAAGAAAATGTATTTTTATAT TTAACAGGTTATGATACAACGGGGCTTGGAACAAATCTTTATTATTTATT GTTACCATGTTTAGTGGCTTTAGCTGGTGCGGATTTATTGGGTGAAGATC GGCGTAGTGGCTTAGATATATTTTCGCGAATAAGAGGAAATGATAAGCAG TACTATTTTTCGAAGAGCATCGTTGCTTTTATTGCTGGAGGGGTAGTATT TTGTTTGCCTTTAATTATGGAACTTTGTGCATTAATGTTAGTGTATCCCT CTACACCACTTGATTATTTCGTAGCAGAAGTACCGGTTACATATGGCGCG ATGTTTTCGAATATATTTTATAACAGTCCGCTTACGTACGAGTTGATATT CCTTGTAATAGGCTTTGCTTACGGAGGATTGTTTGCTTTGATTGGAATTT TAGTGTCTTTTTTTAGTTCTAGTAAATATGTAGTTTTATTGAGTCCACTA GCTATTTATTATGGTGTGTGGATAGTGTTTTCTTTGATTGGCTATCCAGA GTTTAGTCCGTTTGGTTTCTTAACTCCAAAGCAAGGTTACCCCTTAAATT TCTATATTATTTGGGTAGAATTTCTACTTCTTTTAGTAGTGATAATTATG GGTATTATTTGGAGGGTGAAAAATGAAAAATCATAA ORF3283 (SEQ ID NO:107) ACCAAACTTCTGGAACTGTTAAGACAAAGTATAGTATATACAGCAAAAAA AAATAATGATAGGTATGTATTAATGTATAAAGATGGATATACATCAAGAA ATAATACATACTACGGGGAATTTTATGGTCACTATGCAGGCGGAAAAGAT AAATTTTCATATAAATTAGAAAAGAAAAATAATAAAAATGTAAAATCACA ACTTATTGTAGATTTATTCGTAATTTAA ORF3291 (SEQ ID NO:108) AGAAGAGGTGTAAGGAAAATGCTAACAAAAGAAATATTACCTATTGGAAG CGTTGTTTATTTAAAAGAAAGCCTGAAGAAAGTTATGATTACGAGTAGAT TAATTACGATTCAGGGAGATGAAGAAAAAGAATTTTATGATTATGGAGGT GTAGTTTATCCAGAGGGGACAAAGGACGACAATATTTTAGCATTTAATGC AGAAGATATAACAGATGTGAAGTTTAGAGGTTTTGTAGATGATGATGAGG TAGTCTTAGTGAAGAGAATGAGAGAATGGCAGAAAGAAGAATTTGGCGTT TCTCCAGAAGAGGAGGATGAGATACTTGAATTATGA ORF3316 (SEQ ID NO:109) ATGAGATATGAAGCAAAAATAATTTCAGAAAATCCTAATATTGAAGAAGA GTTGAAAATTAAAATAAAAGATATTGAACTTTTATGTTTTGTTGAAGAAT ACAAATGTTCAGTAGAGGTTGGCCAAGAATATATTGTTGAGTTAGAGACG GTCGTTTTCGATGATTTAGATATTGAGAAAAGTACTTTACAAGCTAAGGA AATAACTCAAGTAGCAGATAGTTTTGCATACTTTATCAGAGGCGTTTTTC ATCCTTCTAGTAAGAAAATAGATTCAGGGATAGAGATTGATTTAGCAGAT GAGGATATTTCTGATTTTTGGTATTTGGAAAATCAATTTGTTGCATTAAA TGTTGATAGATTCAATATAGATGTTATAGAAAAAGTAAATAAGTAA ORF3324 (SEQ ID NO:110) GAAGTGATAGGTATGGCTCGAATCGAATATGAAGAAAAAATTCAAAAAAG CCTACTGGTTTTATACTTTAGGGGGTCTACCATACAGTCTATCTGCAGGG AGTATGGTATTCCTCGTTACGAATTTCACAAATGGATGAAGTTACATGAT GCCGATAAACTGGAAACCAAAGAGGTGAAGACTTTCCTACAGATAAGAGA ATTAAAACAACAAAAAAACAAATTAGAAGAAGAAATTTTGTTTTTAAATG AAGCAATCAATCTGTTGGAAAGTCCTTGA ORF3325 (SEQ ID NO:111) GAAATTACGAAAGGAGTTGTGCATTTCTTGAAAAGGAAATTAGTTCTGGC AATGGTACTAATCAGCTTTTGTGGGATGTTCCTCTTATCGCCTGAACGAG TTCAAGCTAGTCAAACAGTGGTTGAGGTGTTCATTTCAGAGGATGATTTG GATGTCAGTGAAGAAAACATACAGGAAATCCCTAAAAAAGAACTGGCAGC CTCTTCCGATAAGGATAACAAACAACCCATATTACCTAAAGCAGGTGATA CAGTAACTAACTATACCTTGTTGGGTTTAGTGCTCGTCCTTATTTGGTTG ATAATGCAAAGAAGGAGTAAGAAGAAAGAATAA ORF3326 (SEQ ID NO:112) TTGTCGTCTAGACAAAGGAGGAAATTTTTTATGAATAAATTAGTATTAAG TACGTTAAGTGTAGCAGCAATGGGTATGGTGTTTTTTAGCGGAGGGACAG CCTACGCGGCAGATAAAQAAGGAAATACAGTAGTGGAATATTCTGTTGAA GGGGATTATACCCTCGTTGTACCTGAAAAAGTAAATTTATCTAATGATAA CGCCACAGAAATGTCTGTGAAAACAATCAATCGTAACTTAGAACCAGGAA AAGAAGTAGAGGTGACATTATCTAGTGGATTATCAGCCGATGGAGAGATT GAATTACAACGGGTTGGCGCTATTTCGGACGTAATAACCAGTAGTTTTAA GAGTAATAATAGTGTAGTACCCATGGCTAATCCCGTCATTGGAAGCTTTT CAGGATATGCGATGGAGGAAACAGAAGTAAGTAAAATTCAAATTGGAAAC CCTCAAGGAGACAAAAAAGCTGGAGCATATCAAACAACGTTAACTTTTAC AGCTGCTTTTAAATAA ORF3327 (SEQ ID NO:113) AAACTAATTAGGAAAGAAGGAGGGGAGCTGATGAAGAAGTTTTCCATGCG AGTGGTGCTTATTATTTCTGTGCTTTTTATTGCTTTTGGGAGCGCTAATG TTTCTATCGCACAAGAGATGGATACAACGAATAAGCTTCCAGAAGAGGAG CTGGGTTCTCTGGATACCTCTAATCTTATTGCAGAAGAAGTCGCGCAAGA CAAACCAGCAGAAGTGGATAATCTAGAAGAAATCCCAACTACGGATGAGT TGATGCAAAATCCAGAGGTTCTTGAACAGCCTGTTGTTGATTCCGATGAT CCGGATTTAACAGTGGTAAGCTCAGGTGATTTTTGGACGCTTTATTATAA TTCTGCGAACGATGAATATAGCATGCGTATGTTTGGCAACGTGCCAAGCA GTAAACCAACCGCTTGGAATAGTTATTTGAAATACATTAAACATATAGAG ATTGAAGAAGCTACTCTGACAGGAAGTTTTGCATCGTATTTTGACAATAG CGCTTTTCCAGCACTGGAAAGCGTGAGGATTGAACAGTGTAATTTGTCTG GAGTGACGTCTTTTAGAACCGCATTTAATAATCACTTAACACTTGAAAAA GTTATTATCAAAGACAATGATTATCCCACAACATCATCTTTACTTACTAC GGAATATATGTTTTCTCATGCTATCAAACTTACGGAGCTTGATGTGAGTG GTCTTGATACGAGTGCTGTAACTAATATGAAGAACATGTTTGGTGGCTGT AACTCACTTGAGGAACTGGATTTAAGTAATTTTGATACGAGTTCCGTTAC TAATATGTCAGGCATGTTTGGATACTGTGAATCACTTGAGAAATTGAATG TAAGTCATCTTGATACGAGTTCAGTGACTGATATGAATGCCATGTTTTAT GGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTC AGTGACTGATATGCGTGCCATGTTTGCTGATAATGAAAAACTGGAGAAGC TTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATGGGTACCATG TTTAAAGATTGTACAGCGTTAAAATCTTTATATCTGGATAATTTTACGGA TGCAGCAATTATGACAGATATGTTTAAGGGAACCACCTCCTTAACTTACT TGTTTGTCAGTCACAATTTAAGTACTTTTACTAGCTTAGAAAATACAAGC TGGTATGACGAAAAGAATTGGGTGCAGTTTTCTAATCTCTCGCAACTACA GACATATCACCGGAAACAAAGTGAACCTACAGGCTACAGAAAAGGCGCTT TCCTTTCTCTAACAATGGATGCGATGGGTGGAGAATTTGAAGACGCGGAG GAACAAAAAGTACAAAGTAAAATTTCTGGGGAGTACTGGGAAGAAGTGAT TCCAGTAAAAGAAGGACATTACTTTGACGGGTGGTATCTTGATCAAAATT TCACTAATAAGTTTGATTTTTCTTTACCAGCAACTGTTTCAGCAACCCTC TACGCTAAATGGGTAGAAAATTATACGGTGGTTATTCCAGCTTCTATTTC CTTAAATGAAGCTACTGAATTGAAGGTAGAAGGGATTAATCGAGGGGATA AAAATTTGTCCGTGGGATTAAACCGAACAGCAACGTCTGTTTCTGAGAGC AACAAGCTAACTTTGGCCAATACAGCAGACACAACAATCCAATGTTTGGC ACCACTAAGTTGGGACGGTTCCGAAAACAATCCAAAAAATGCCATTTTAA CCCTAGCACCAGGTTCGGAAATAACAGAAGGCGAGGCAGTCCTGGCTATT GAAGCACCAGAGAATATCCAGGCAGGAACGTATACAGGGAATCTGGTATT TTCGATTAATTATGAATAA ORF3361 (SEQ ID NO:114) TCCTGTTTCAATCAAATAAAGGAGCGTATTTTAATGAAAGAATTAAGACT GTTTTTAGATTATAAATGTTATCCTGTTTGGGTATATAACGATGCGGGGA TTTTAAAGGAAAATGATTTGCCGGATGAATTGAAACAAGATGAATATGAT AAATTGTTCATAGATACTGAAATTGAATTTCGATATGAAGCTTTTAAAGA TGAGAAAGAAAAGGAAGAATTTTTTCATGAGTTCATAGAAGTTCAAAAGC ATTTGAAAGAAACATTAGGTAAGGAATACAATATCGTTAATAAGATTTTA GTTTAG ORF3362 (SEQ ID NO:115) AAGGAAGGTAATAATATGAAAAAAATTATGAAAAAAGATGATTATTCTAA AATGCCATGGGTATCAGCGGAGGATTTATATCTTTTATTTGAACAAGCAC TCAAGGACTTTAAGCAAAGCAAATTAAGTAAAAAAGAGTTTTTTGATATT CTTGATGAATTGACTATGAGGCAAGTAGATACCTATGAAATTTTAAAAGA ACCTTTGAGAGGACAGCTCGACAATGAGTTATATAATTTATGGAACACAG AAAATTATGATGATGTAGATATTATTACATCATTGTTAATTAATTTAGGC TTGAAAAATACTTATAATAAAATGAAAAAATCTATTGAGGATACTTCGGA AATATCACCAGAAATACTTGAGGAAATACAAGATGCAATTGAAGAAGTCG GAGATAATATAGATGATCCATATCAAGATTATATGAAGAAAATGTAG ORF3365 (SEQ ID NO:116) GAGGAGATACATTTGTTTAATGAAAAAGTAAAAGAAATGATCCGAGAATT GGATAAATATAAATTACAAGATAAATGGGTTCGCTTTGAAAAACTTTCTA AAAACAAGAAAATTGATAGTGAAACTTTTCAAGATGAATTTATTATTATA ACAAATGGAATTCTTCATGTGGAAAATAAAAAATTCCAGATACTTCATTT TTTTTCTAATGGAGATATAATTAACCAACAAGTTGCCAAAATTAGCGGAG AAAATGAATTAAGATTAGTTTGTGATACAGATGTTTCCTTAATTTTTATT GATAGGGAATATTTCTTAAACTATGCTACCAATAAGCCTTCTTATATGGA GTGGCTTTTAGAAGAAACATTAATAAACAATAAGAACCTTTATAATGAGT TAATTAAGTATGACTTGTCCGCAGAAGAAAGAATAGTCTATGCCCTCCAG TACCTATGTGACAAATTAGAAATTGAAAGTGAAAATGGCTACCAACAAAT ACCTAAATATATTAATAAGATAAAAATGGCGAAATACGGCAAAATATCTC GCAAACAACTAAACGAAAAAATAATACTTCTCCTCGATAAGGAAGTATTA AAAGAAAAAAAAGGAAGATTCTATATAAAAAAATCAGCATAA ORF3378 (SEQ ID NO:117) CATCTTTTTTTTGCTATATTAAAGGATAGTAACGTCTCATATAGGGAGTG GAGAAAAAGAGTGTTAAATAAAAAAAGAGTTATAGTTGGGGTTTTGCTAC TATTACTAAGTTTAATTTCTATTAGCTATTATTCAGAAACCTTTAAACTA ACTTTAAGCTGGTTGTTATTTGCAGTAGTTTTAACGGTTCTTTATTTTAG ACAAGAGAAAAACTTTCAATTTCAATGGTCAACATTGATAACCTCACTAA TAATTAGTTTATTTTGGATGGCTTCATCATTCAATGGTGGACCATATGGC GGGAATTTTGTTTTTAATAGTATTATTTTAGCAGGAACTTTTCTTGTAAT CACTATCTTTGTTTTACTTTTATTACTTGAAATGCGAACGGAATATAAAG CAAGACCGAATCGCAAAGTAAAATGGCCATTTTTCGCACTATTTACGAGT ATTCCATTCGTGGTCTGGATGATTTCATTTCTAGCCTATTATCCAGCAAA AATGACATTTGACTCCTATTACCAATGGGGAATGGCTCACGGTATTCGCC AATATAGTCAGTGGCATCCGCTTTTACACACTTTGTGGATAGAAACAACA AGTGCGATTTACGACTCACCTTCGAGTTACATTTTTTCTCAAATAATTGT TGTTTCATTAATCGTTGGCTTTGCTATTTATACTCTTGTAAAAATGGGCG CGCATATTTGGATTGGTGTTTGTATTTCAATCGGCTATGCCATTTACCCT GCAGCAATGTTTTATTCTGCAACAGCATGGAAAGATTTTCCATTTGCAGC CTTTATATTACTTTTCACCGTTTTAATTTTAAAAATAGTACAATCTAATG GAATGTGGCTGAAAAATTGGTGGCACCTTATCGCTTTTGTTTTAGTAGCT TTTGTTTGTATAAATTTACGAAACAATGGAATGATGATTATCATCGTATC GCTTCTGTGCTTGCTTATTTTCATGAAAAACTTTCGTCTTATTATTACCG GTATTCTTGTTGGAACCTTGGGACTGAATTTTTTATTTGGTCTGGTTATG ACAAACGGGCTTAATGCGCAACCTAATCCATTAAACCAAGCGCTAGCAAT TCCTTCCCAACAAATTGGGGCTACTTTTTACAATGATGGAAACTTTACTC CTGAATTAAAAGAGTATTTCACTTCCATATTACCTGAAGAAAATTGGAAA AAAGATTACAACCCTTATACTGTAGACCCAATTAAGCATGATACCAAATA CAATTCATCCGTCATTGAAGATGATTTTGGACTATACATTAAAAATTGGT TCAAACTCTTAACGGCTAATTTCGGTACTTATGTAGGGGCTTATTTAGAT CAAACAGCAGTCATTTGGCAATTCTATTCTCCAGAAAATTATAAAGTATT CTTTGATACTTCAGCGAATATTCAAGATACAAGATATGATGTGAGAGCAT TCGCCAAATTCTTCCCAGAAGGTTTATCGGAAGAAGAGATTAATAAATTA GGATATGAAGTCTATCAAAATGAATACAAAAATGCAACTGGAAAAGATGC TGTTAGCTACAATGAGTATAAGAGACGGATTGATGACTCTACTAATCCAC TTATTTCAATATCTAAAGCTCCAAGTCTGAAGAAAATAACAGATAGCATT TATGCAAAAACAACAAATGAGTGGCAAAATTATTTATTAAAAGGAGCCAT TCCATTAGTATTGCTCATAATAGCAATTGCTGCCGTCTGCCTCCAACGTC CTAAAAAGAAACTTCTTATTTTTGCACCTGTAGTAATGGCACTTATTACT ATAGCAATCGCAATGCCAGCAACAGACTTTAGATATTCTTATAGTTTTAT TTTCACCGTGCCTATTGTCTTTTTTGCAACTAAATTAAAAAATTACAAAG AAAATCAATTTTAA ORF3379 (SEQ ID NO:118) AAAATTACAAAGAAAATCAATTTTAAGGAGAGAATAATGGGAATTCTAAA TGAGAAAGTAGCTGTACTCTTGCCTTGTTATAACGAGGAGCTTACAATTG GTAAGGTAATTGATGATTTTAAGAAAGAATTACCAAATGCGGATATTTAT GTGTACGACAATAATTCTAAAGATAAAACCTTTGAAATAGCGAAAGATCA TGGTGCTATCGTTCGAAAAGAAATGCGCCAAGGTAAAGGTAATGTAGTAC GTTCTATGTTCGCGGATATAGATGCTGATTACTATTTAATGGTCGATGGT GACGATACCTATCCAGCAGAATACTGCCATGAAATATTAGAGGTGCTTCG CAATAAGGAAGCTAATATGGTTATTGGTGATCGTCTGAGTAATGGTACCT ACACTGAAGAAAATAAAAGAAATTTTCATGACTTTGGTAACTCACTAGTA CGTAATACAATTAATCGTATCTTCAAAAGTAATTTGAGAGATATCATGAC AGGCTACCGTGGCTTTGATCGTTATTTTGTTAAGACTATGCCAGTTTTAA GCCCTGGTTTTGAGATTGAAACTGAGATGAGCATTCACGCATTGGAAAAT CGCTTTTTAGTGAAAGAAATTGAAATTGATTACCGTGATCGTCCAGAAGG TAGTGAATCAAAACTAAACACTTTTTCTGATGGTTTCAAAGTAATTATGA CGATTGTAAGATTATTTAAAAATAGTCGTCCGTTTTTATTTTTCAATTTA TTAGCCTCTTTGTTTGTGCTTGTAGGAGTTCTAGTTGGTTTGCCAGTCAT AATTCAGTTTGCTCAAATTGGCTTGGTACTAAAATTTCCGAGTGCATTAC TTGCAACTGGTTTAATCATAATGGGTATGCTGTTCTTCATTTGTGGATTA ATCCTTGATACGATAGCTCATAGAAGCAGACAAAGCTACTTCTTAGAACT TGTTAAATACCGCGAAAGAAATCCATTGAACTAA ORF3386 (SEQ ID NO:119) AGTATGAAAAAGTTACTTTTGTCCATCAGTATTATTGTCGGTTTAAGTTT GTTGGCTAGTTGTGGTTTAGAAAAGGAGTACAAGCCAGATATAAAAGTAA ACGAGAAAAATGTTTCTTTAAAAGTTTGGGTGGATTTAAATCAGGGAGAT TTTTATAGGAAAGTGGTAGAAGATTTTAAAAAAGAACATCCTGATAAAGA TTATGATATTACGGTTATTGAATCTGAATCTGGACGAGCACAAGAATATG TTCAGAAAGATCCAGAAGCTGCGGCGGATGTATTTATAACTCCGAATGAC CGTCTAGGACAACTGGTAGAGTCTGGTGCGGTTTACCAATTGACAAAGTA TACAGATGATATTAAGAAAAATAATACACCAACCTCCATTCAAGCTGCTA CATATCAAGATAAAATGTATGGTTTCCCTGTGACGGCGGAAGCGATGTTT ATGTATTATGATAAGCGCGTTTTTTCAGAGGATGATATTAAAACTTTTTC TGGAATAACGTCTAAAGGGAAGCTCGGAATAAATCTTGCGGAAGCTGGCG CGGATTATCGTGAAACACCTTGGTTTATTGCAAATGGTACATATCTTTAT GGTGAGAACGGCGAAGATCCTTATGGGACAACCTTTAACACTCCAGAAGG CGTCCAAGTATTGAACTGGATTGGTGAGCTGAAAAATAATCCTAATATTG TCGCTGTAAATGCAGATGAGATTAGTGCCCTTAGATCCGGTAAAATAAAT GCTGTTTTTAGTGGGGTTTGGAATAAAGATGCGATACGAGAGGTTTTGGG TGAAAATATGGGAGTGGCAGTATATCCAAAGGCCGATTTTGGAAGTGGTC AGGTAGATATGATGGCTTTCCAAGGAAGCGGGATATACTGTGTGAACGCA TTTACTAAATCGCCATTAGATGCGATGGAACTAGCTGATTATATTACTAA TGCGGATGTGCAGGAAAAAGCTTTTAAAGAGTTAGGGAAAATTCCGAGCA ATTTAGAGGCACGAACTAGTTCTACAGTAGAAAAGGACGATGTGGCGAAA GCAGTTATTGATATGACATCCGGAAAGCACTCCGTTTTAATGCCGAAAAT ACCTGAAATGAACGTTTTTTGGCAACATATGAACCCGCTATTAGTAGATA CTTATAAAGGCAAGATTAAGAAAGAAGATTATCCAGAGGCGCTCGATAAA TTAGTCAAAGATATTACACCAGCGAAATAG ORF3401 (SEQ ID NO:120) AATCAGCGAGAGATAGGTGTAAAGAGAGTGAAGAATAGGTTAGCTTATAT TTTTAATGCGTTTTTTATACTTATTTTTGGTTACTTACTTTGCATAAGCA TTTTTAAACCGCTAGAAATTAGTTTTAATCATCCGAGTATATTTATATTA TTTAGTGCTGCGGCGCTTTTAGTACTTATAGGATTCTATCAATTTTCTAC TAGATTGAATACAAAAGGAGATGGTGTAATAACCATCTTTTTGGTTAGCT TGATTATATTAACTCAAATTTATTTGCTTTTCTCCTTGCAAATGAATTCA TATGCAGATGCTTTTCTTATCAAGGGAGAAGCATTGAATATGCTTTCTAA TGGAGGGCATGCAACAACGCAGAATTATTTTTTAATGTATCCTAATAATA TATTTATAACAATTATTCGATACTGGCTATATTCTGTTGGAGGGACGCTT GGTATTACTAATACGTATTTATTAGAAAGTGCTTTCCTTTTTGTTTGTAT GAATATTACTATTTTTGTATTGTACTGGATTGTTCGTAAAGAAAATGGTA ATAAATTTGGGAACATCTACTTATTAATTGTTTTATTCTGTGTGCCATTA TTTGGTTATATTTGGTATTTCTATACAGATACACTTGTACTGCCATTTAC AGCGCTGATTGCCTTATTTTATTATCTATACACGAAAAGTAGTAAATGGT GGTATTTCATCATTATTGGGCTGCTGTTTGCAGTAGGTTATCAAATTAAG CCGAATATCATCATTTTACTTCCAGCAATGCTTATTCATTTATGTTTTAT AAGAAATTGGCGTAAAATTCTATTGAACACGGTCATCGTAGCAATTTGCT TTTTCGGTTTAAGCACTGTTTTTACACCAATCGCAGAGAGTTATGACTTT AAGAAAGACCCAACCATTGAATTTCCTCAAACACATTGGATTATGATGGG GCTTGGCGATCCAGCCGGTCGTTATAACAGCAATGATGTTGCTTATACTT CACAATTTAAAACAAAAGAAGAAAAAGAAGAAGCCAATATTGAAAAAATT AAAGAACGTATTGAAGAACATGGACCGCTTGGCTTAATAAAGCTTTTTGA TAATAAGGTGTTAAATACTTGGACAGACGGAACGCGAGCATATACGTGGT ATGTTAATGCTGCACTTGATTATCCAGCTCCTTATGATTACTTCTTTGGA GATAAACGGGTTGTCACTGAATTACCTGCTCAGCTGTTCCATATTATTAA TTTGTTTTTAATTTGTCTAGGTGCTTTACGTTTTTATAAGAAAAGGGAAT TTGATATGTCCTTTTTCGTTAATATTTCGCTAGTAGGTGTTTGGCTATTC CACTTATTCTGGGAAGCAAATCAGCGTTATATTATGTTTATTACGCCATT AATGATCTTGTCCTCTATATATGGGTTTAAATTTATAGTAGAATCTTTAT ATACGAAAAAATTTGATTTGAAAAAAGGGCTAAGAAAAGGCTTTTTAATC GCGAGTTTCTGCGTATTTTTATTAAGTACAGTTGCTTTTGCTTTTATTGG AAATTCGGTAGCAGGCGAGTCACAGGATATCAATAAATATCTTGTAAAAC AAAGTTATGCGCATATAGATCTTCCTGTTACTAGCAAACAAATTGTTAAG CAAACGTTTAATGTAGATTCGCCGTTCAATTCTATCCAAATAGCGGTTCT AAAAGAGCCAGATGAAGCTAGTAAATATCGTTTGAAAGTTGTAGATAAGA CAAATAAGAAGGATATTTACGATGAAGTTATAGCTGGATCAGATTTTGTA GAAGCTACAAATTACCAAATTAATGTAAATGAAAAGCCAAAAGGTAAAAC TGAATATGTTATTGAAGTCTATCAAGTGGAAAATAAAAACCCTGAAAAAC CATTAGTTTTAGGTACCTATACTCCAGATGCAGTAGATCTTTATCCGTAT GGAGCACTGTATGTTAATGGTGTTAAAAAAGAGAAGCAAGATATGGGCTT CACTGTCTCACATGTTGCTTCTGAACCAATAATACCGAAATATGTCTCCG CTATTTTTGATTTGGGTGTTATAATTATTTTTGCAGGAACATATTATGTG TTTAGAAGGAAAACTGGAGATAATAGATGA ORF3402 (SEQ ID NO:121) GACAATAAACAAATTAAGGAGTGGTTGGAGAATATGATAAATAAAAAGTG GATGAAAATTGTAATGATTCCGATGCTAGTTGTTCCAATGTACGGTTTGA CAACTGTTGGCGGACAATTACAAGATTCATTAACTGGAGAAAATTCCTTT GTTAAAGAGGTTGAAGCTGCAACGACAGCATCGCAACAAGCATTTATCGA CAAAATAGCACCTGCTGCCCAGGCATCTCAAGAAAAATATCATCTGTTAT CTAGTATAACTTTAGCTCAAGCAATTCTAGAATCTGGTTGGGGAAAAAGT GGACTTGCTACACAAGGATATAATTTATTTGGTATAAAAGGGAAATATAA TGGACAATCAGTTATCATGACAACTTCTGAATATGTGAACGGTGAGTGGA TTAAAATTGATGCTGAATTCCGCAAATACCCTAGCTGGAATGAATCTGTC ACTGACCATACTCTTTTATTAGTGAACGGAACTTCTTGGAATAAAGACTT ATATAAGAAAGTTGTCGACGCAACGGATTATAAAGTAGCTGCAATGGAGC TTCAAAAAGCTGGATATGCAACCTCTCCTACATATGGTGCTAGCTTAATT CAAGTAATTGAGAATTATGATTTAGCCAAATATGATGTTTTATACGACAA AATTCTTACTCAAAAATCCACTTCCGGAAAAGCAACTGTTACAAGTCCGA CTGGAAATGGTGTATGGACTTTACCGTATAAAGTAAAAGGAGTGCAATCT GTTAGTCCAGCTAGCACATACGCTAACAAGGATATCGATTTAGTATCTGT TGCTACAACAAAGAGAGGTACGTACTATCAATTTAAATATAATGGTAAAG TAGTTGGTTGGGTAGATGGCAAAGCATTAACTATTTATGATAGTGTCAAT TATGATAAAGTAAATGTCGGACGTGCTAAAATTACTAGCCCAGTAAGTAA CGGTATCTGGTCTAAACCATACAATGTTTATGGAAGAGAATTTGTTACGA ATGCAACAACTTACGCACAACAAGAAATTAAACTTTTACGCGAAGCACAA ACTGCTAAAGGTACTTATTACCAATTTAGCATAAATAATAAAACTATTGG TTGGATTGATAAACGAGCTCTCACTATCTATCCGTATGATTCCATTATTT CAAGTAAAAATGTGAACCTTGACGGACAAATTACTAATCCAACCGGAAAT GGTATTTGGACTAAAGCGTACAAACTTGAAGGAACAACTTCTGTGGCGCA GGCTACGAAATATGCAAATAAAGATGTGAAAATCAGCCAACAAATCGAAA CTCAACATGGTACTTATTACAATATCAGTATCGATGGGAAAGCAATTGGT TGGTTAGATAGAAACGCTATTACACTGTATGATCAAGAGGAATACAATAA AACAGTTGCTATTGACGCAGTAGTAAAAAATGTGAAGGGTAATGCTGTAT GGACAGAACCTTACCGTACAGTTGGTACAAAATTAATCGGACCAGCGGAA ACTTACTTGAATAAAGAAGTGGAAGTCGTCCGTGAAGCAAAAACGCCAAA AGGAACTTACTACCAATTTAAATCTGGTGGCAAAGTAATCGGCTGGTTAG ATAAAAAAGCTTTCGATGTATATGACAATATTAATTACAACAAAGCGGTT AATTTAGACGCTGTAGTGGAAAATGTGACAGGTAATGCAGTTTGGACGGC TCCTTATAAGAGTAAAGGTGTTAAACTTGTTACTTCAGCAGCAACCTATA AAGGCAAGGCAACAAAAATAACTCGTGAAGCGCAAACAAGTAGAGGAACA TATTACGAGTTTAGTGTTGATGGTAAAGTCATTGGCTGGTTAGATAAAAA AGCTTTCGATGTATATGACAATATTAATTACAACAAAGCGGTTAACTTAG ATGCTGTAGTGGAAAATGTGACAGGCAACGCAGTTTGGACTGCTCCATAT AAGAGTAAGGGTGTTAAATTAGTTACTTCAGCAGCCACATATAAAGATAA AGCAACTAAAATAACTCGAGAAGCGCAAACAAGTAGAGGAACTTACTACG AATTTAGCGTAAACGGCAAAGTAATCGGTTGGTTAGATAAAAAAGCTTTT GATGTATATGATTCTATTGAGTACAATAAAGCGATTAATATGACTGGATT ACTTAGCAACGCGCCAGGTAATGGCATTTGGACAGAGCCGTATAGAGTTA TTGGCACAAAAAATGTAGGACAAGCAACTGCTTATGCTAACAAGACAGTA CAGTTGATACGCGAGGCTAAGACTACACGTGCAACTTACTATCAAATGAG TGTAAATGGTAAAATAGTTGGTTGGGTAGATAAACGAGCTTTTACAAACG TTAAATAG ORF3410 (SEQ ID NO:122) GTAGAAAAGGTGGTTAGTATGATGAAAAAACGTATAATTATTCTTGCAGT ATTAGTGGTACTTCTTATCGGAGGAGTTGTAATCGGTGTTTATGCAAGCG GAAACTCTGCAAAAGACAACAATGAAAGCAAAACAACAGCTAAAAAAGCC ACATCTACACCTAAGAAAGCAATTGACACAGAGAAAAAAGAAACAACAAC CAAAGAAGCGACAACAAAAGATTCCGTAACGGATGATAAAGGTGTAGTCA CAAAAGGAAGCTCAGATGTAGAGAAAAACGCACCGGCCAAAAATAATAGT AGTGCAACAGATAAAAGCAATAGTCCAACTACACCGGCTTTTTCGTTATC TAGTACAGGCTTCAAAACTTCCAATGTATCTTCTGTTCTTGGTGGAACTG TAACAACAACGTATTTGTCGAGTGCCCCATCATTCGAAAAAATCTTTGAA AATTTAACGATTGAAGTGAATCAATATAAAGTAGAGCATGTTGTTGGTGC GAATAAAGCAGTTAGTGCAAGTAATCCAGAAAGCTATTTAGCAAATAAAA ACGGCTATGTAATCACTTTAGACATTTCCATTAAAAATACTTCTGCAAAA GATAAAATGTACAAAGCAGACCAAATTACACTTATAGGAGCAAATGAATT TGTAGGAGGAAGCTTAGATAATTTTGTTCCTTCTAATTTTCATCTTATAG GAAGTAAAGCAGATCCAAATATTTTCACCGCTGGAAAAACAGCTCGTGGG CTTCTTACATTTACAATGACAGAAGCTGTGTACAATGATTTAGCAGCTGA CTCAAAAATAGGTGTTCCAAATCCTGATAAATTTGATGCAAGTGTTTCTG AAGCTAATGCAGGCGATGATGTAGTTGCCTCATTCCCAGTAAAATAA ORF3457 (SEQ ID NO:123) AACGGGGTGTCAACGACGAAAAACAATATAGATTACATTAAAACAGTACA AAACATAAAAAGTTTTTTTGATGAATTTCAATATTTGGTTTTTCTGCTAG GTTCTAAAAATAAAATAAAGCTCAATACAGACGGATTAATAGAAATAAAA GTGTTAACAGGCAATAAAATAAGTTTGACTCCTATAGGTCACTTAGTTCA ATTTTACTTGGGAATATTAAATGACATGAAAGCACTACATCGCTTTATTT TAATTAAATGTTATATTGAGATAAACAAAAAGATATTTTAA ORF3501 (SEQ ID NO:124) ACTTTCCCTCCCAAGAAAGCCAGTGGGGCTGATATAGCTAAAAGTAAAGG TGGCGTTACTTTAGAATCAACAATAGGAAATAAAAATATTGAAATGCCAG ACTGGGATTTTAATAATCCTGAGTCAATGAAAGCATGGGATTTGGCTTCT GGTTCTTATGCAGAACAAGTTTCTGGTGAAGTTCGTGCAGTAGTTGGTTC GGATTTGAGAAAAGGAAATATTTGGGAAAATGTTGAGTTACCTAGATTAA AAAATAATCCTAACGTAACGAAAATAACAACGATTGATCCTAAAACAGGA CTTGAAAAAATAATTTTTGAAAGGAAGTAA ORF3593 (SEQ ID NO:125) GGAGTAGTGACAATGAAACTAATAATGAATGCAGATGATTTTGGGTTCAC AAGAGCAATCAATTACGGAATCTTTGATGCGCACAATTTAGGCGTTTTGA CTTCCACGACATTAATGGTAACAATGCCTGCTTTTGAACATGCTGTAGAC TTATCTAAGCAAACACCCACACTTGGAATAGGCTTACATCTCAATTTAAC GTTAGGTAAGCCGTTGACAAATGGCGCATCTTTAGTGAACCAAGCTGGTG AATTAATAAAGCCAAAATTTATTACGCCTGAGTATCCCTATAATGAGGAA GAAGTGTATCAGGAATTTAAAGCGCAATATCATCGCTTTGTCACATTTAT GAAAAAGAAACCGAGTCATTTGGATAGCCATCTCTTTTCTACAGATATCT ATCCGGTTGCGGCTAGTGCTGCGAAACGTCTTGCAGAAGAGGTTGAAATT CCACTTCGAAATCATGATACAGTGGGCTTTCAGCATGTCGAGTTTATTTG GGAAAAACCGCTTGAAATTCCATATGGTGCGTATGAGAACCTAGATTATA TTTATGACTATGCAGAATCGATTTTATGTTATGATTATGTTGAAATCATG ACGCATCCTGGCTATCTCGATACGTTTATTCTGGAAAATTCAACATTCTC AACGCCACGCGCGAATGAATTAGAAAGTTTAATTTCTCCTAGAATGCGCC AGTTTTTAAACGAAAACAATGTAGAATTAATTTCCTATCATGATATTCCA AAAAAATGA ORF3594 (SEQ ID NO:126) GACGGAGGGAAACTAATGGAAGGCACTGAATTACAGTCATTTAAAATAAT ATCAAGTGCAGGAGATGCCTCTTCCTCGTTTCTAAAAGCAATTCGTCACG CAGAAAAAAGTGAATTTGCGGAAGCAGAAGCATGTATTGAACAAGCAAAT CAATCTTTAAGAGAAGCGCATCATGTGCAAACATCCTTGATTCAAGAGGA AGCGGGCGGGGACTCAAAAGAAGTATCCTTATTGCTTATTCATGCGCAAG ATCATCTGATGAATGCTTTTGTTTACTGCGATTTAGTTAAGTCAGTACTT AACTTGTATAAGCGTTTGGATGAAAAGTAA ORF3745 (SEQ ID NO:127) AAGGTGATTAACTCATCTATTTATTATTTTAGGAGGTTTTTTATGAAAGC AAAAAAGAGAAAAGAACAAACATTTCATGAGTATTTTAAAGAATGGGTAG ATCTTTATAAAGTTGGAGCGATACGTTCAATTACCCTGCAAAAATACTAT GTAACAGAACAAAAAATTCAAGAACTTGTACCAGAATTAAAAATAAAGGA CCTAGACCGTTATACTTATCAGCAGCTGCTAAATAATTATGCACTTACTC ATGAGAAACAAACAACTATGGATTTCCATCATCACCTGAAGGGCGCTATT TTAGATGCGGTAGATGAGGGGGTTCTAAATCAAAACCCCACAAGAAAAAT TGTGATTAAAGGAAAAAATCCTCGACCTAAAAAAGCAAAATTTTTAAATC AATTTGAAGTTCAAGTTTTATTAAAAGAATTAAATTTAAAGGAGGATATA AATTGGGATTGGTTTATTCTATTAATCATTAAAACAGGACTTCGATTTTC AGAAGCATTAGCTCTAACACCTTCAGACTTTGATTTTTCCACACAAAAAA TTAGTATTAATAAAACCTGGGATTACAAAATGGTTACTGGTTCTTTTCAG CCAACAAAAAACGAATCTTCCAATAGGAAGATTCAAATTGATTGGCAATT AGCAATGCAATTTTCCCAGTTAATTAAAATGAAAGATTCTGATAAACCTA TCTTTGTTAAAAGTAGAGTATTCAATTCTACTATTAATAATCGTTTAAAA GTGTTGTGTCAGAATGCAAATATACCAACTATTACAATTCATAGTTTACG ACATACCCATGCATCTTTGCTATTATTTGCTGGAGTTTCAATTGCTAGTG TTGCGAATAGGTTAGGTCATTCAAGTATGACTACTACCCAGGAAACATAT CTTCATATTATTCAGGAATTGGAAAATCAAGATAATGATAAAATTATACG CCATTTATCAATGTTAATGTGA ORF3792 (SEQ ID NO:128) ATGGAAACAATAAATCATTTTTTTGAATGGGCTAAAAATAATAATTGGCA AGTAGATTTGTCTGCTGTAGAGAAAAACTTGCCAGAGCAGATTTTAAAGA GGTATGGAAAGTTGCCAGATGCTTATAAGGCTTTTTATAGACAACTTAAC CTCTGTAGCAATGCGGGTGACACTTGTTGGTTTTTATCGGAAGAAGATTT TTTAGAGAATGAGGTTGACGCCTTTTCGTGGAATTCTTTTGAACAAATGA GTTTAGAAGCAGCAGAAGGCGATACAAACTTAGAAAATGAAGTAAAACTA TTTTGGAATGCGCATTTACCAATTATGATGAGTGTTGGCGGTTGTTATGA ATATTATGCTATCACTTTAAATGACGGAAATATTGTTCATGGTTCGGAAC CAGAGTTTGAAGAAAGTTCGATTGTAGCAGAGTCGTTCGCGGATTTTTTA CTGAAAATCGTGGCTGGAGAAATAGTGATAAGTTAA ORF3793 (SEQ ID NO:129) CATAACGTAAATACTCGGAGGTGCAAAATGAAGGTTATCCATTTTTATAG TGAAAATGCGGACTATGGCTGTTTCTCTAATTTCTCTTTACATCCAATTG TCATAGACGGCGTGACTTACCCAACCACAGAACACTATTTCCAAGCACAA AAATTTATAGATAAAAAAATTATTAAAAAAGTAATTAATACGAAAAAACC AATAGATGCAGCAAAATTGGGTAGAAATAGAGACTTCCCACTGCGAAAAG GCTGGGAAAGTATGAAAGACGAAGTGATGTTAAAAGCAATCAGAGCAAAA GTAGCGCAACATTCGGAAGTGAAAGAAATGCTTTTATCCACAGAGAATGC TATTTTAGTGGAACATACGGAAAATGATCATTATTGGGGCGACGGCGGAG ACGGCTCTGGAAAAAATCGTCTAGGCAAGATTTTAATGAAAGTCAGAGAC GAATGA ORF3840 (SEQ ID NO:130) GAAAACATAAACTTGATGGTGGTGAAACAAATGGACGACTGGTCAACTTT GATAGGCGAGCTAGAACATAATACCCCAGAAAAAGTTTGGATTGTTAGAG AAGAACTAAACATATCGGAAGTATTTGAAATACAAAAATTAGAGGCGCAT TTTATTTTAGTTTTAGAAGGTGTCTTGCGTATGGAAAATGAACATCAACA AATTCTGCATTATTTTAGGGAGAATAACGTCATATATCAATCTCCATATG AATTAAGAGTACAAAATAAACTAAGACTAGTTGCTGAAACACCTGCTCAC ATTGTTTTACTGCACCGTGAGTTTTTCCTTAATTATGCAACAAACCAACC TGCTTATTCTGAAAAATTAGTGCGAGCAATTATGGATAATGCCGCGAGTT TTATGTTTGAGTTAATGAAGAATGACCTTAAATCAGAGGACCGATTGGCT TATTCATTACAGCAGCTATGCCAAAGTTTAGAATTAGAAGTAAAAAATGA GTTTTATCTACTGCCTCATTATATTAATAAGAATAAATTGGCGCTTTATA GTGATATTTCGAGGAAAAGTTTATACAAATACCTTCAAAATTTAGAAAGA AAAGGACAAATCAAAATGAATGGTAATCAAATACTTGTCCGCATTTCGCG ATTCACAAATAGCGAGAATGTAGATTGGTTGTAG ORF3913 (SEQ ID NO:131) GAATCCATTTGGAGGTGTGAGTATATGCTAAAAAAAACGAAAAAAAATCT CAATGAAATTAAAACTATTATCCAGCAAAAACCTTTTGATTATGAGAAGG CAGAAAATTTGATAAGTGAGTTAAATCTTGAAGAGGCCCTACTAGAATTG GAGAACATCTTACTAGCTAGCATAAATAATAGCGATGAGAACGCTCGAAT ATTTGCCTATGAGTATTTATATTATTTTGATAGCGAAGCAGTTTTTCAAG CAGCCCTCATAGGGACAACGGACGACGATGATTTAGTTCAAATGTGCTCC ATAGAGATTTTAGGAAATTTGGTTAAAGTAGAAAGTCTCCCGTATTTAAA GAAGGCGTTGGGCGATAACAACCCTGATGTACGTTGCTTTGCTGCTGAAT CAATCGGTTTTGTAGGGACTGACGAAGCGAAAGCGATACTGCAAGAACAG TTAAATAGAGAAACGGATTCTTTTGCAAAAGTAGGTATTTATTATGCGCT CTATCTTCTTGGTCGAGAAGAAATGTTGCCAAAGCTCCTTTCTCTACTAG ACGATAATTATCATTTGACGGTGATTAGAAGCTTGGATGTTCTGAGAGAC GTTGTTAATCAAACAAATAAAGAAAATATATTATTAAATATCGAAAAACT TTTAAAGAGAGATATCCCAATTTCAGTAAAGGAAAAAGCGGAAGTGGTTT TACAAGAAATTAAAGGAAGCTAA ORF3914 (SEQ ID NO:132) ACGAAGTCCAAAGCATACACAGAAAAGAGGGCTGTTATGATAAACCTAGA ATGGAAAGAACTAGACCAACTGGAGATAGAAGAAAAGGTTCAAGAGGTAT TAGATTATAGCTATAATACCTGGATGTCTGATAAGAAGAATATTCGTTAT TTTGTACGGGCGTTTTATATTAGATGGGATATGTTGGTTGATATGTATGA AGTGGAAGATGATGAGACGGAAGGCGATAAGTTAAAATATATGTATGATT TCGGCATTAGCGAGCTGGGAAATATTACAGAGGTTGACTGGATAATGGGT TATTGCATGCTAATTAATCCAATCTATTTTGAAGAAAATGATAATTATTT GGAACTTGAGGAGAAAGGGCAGGAAATGCTTCGTAATGTAGCAATAAATA ACCCGGATGACGTCTTTTTGACTTCTTTTGGTATACCTGAAAAAGATTAT TTGAAATGGAAAATAGCGAACAGAGAGCAACTTATTCAGTACGGGGAAGA TAATTTTAGCTATGACTCAGAGTTTTCGAGATATTTTAAACATATTATAA ATTGCAGGGCGAATGAAGAGGTGGAAAAAGAAAGCTTTCTGAAGAAGATT GTGCGCAGGTGGAAGCAACGATGA ORF3921 (SEQ ID NO:133) AAGAGGCATCTTGTGTTGCCTCTTTTTTATGTAATTTCTCACTATTCTAA CTTACCATTTCGAGCTTGGGAACAGCGTAAGTTAGGGGACTTAGTTGTAG ATTATGTTGAAAAGACAAGTGTACAAAATCAATTTCCCATGCTAACTTCA TCTCAACAAAAAGGGATAGTTTTGCAAGAAGACTATTTTGCAAATCGACA AGTAACCACAGAAAATAATATTGGTTACTTTGTACTACCTAGAGGATATT TCACATTCCGTAGTCGAAGCGATAATGATGTGTTTGTGTTTAACCGTAAT GACATTATTGATAGAGGGATTATAAGCTATTTTTATCCTGTATTTACTTT AAAATCTGCTGATTCCGACTTCTTCTTAAGGCGTATTAACAATGGAATCC AACGACAATTATCTATTCAAGCAGAGGGAACAGGTCAACATGTCCTGTCT CTAAAAAAATTTAAAAATATAGTAGCAATGTTTCCTAGTGAGGGAGAACA AAAAAAAATCGGTTCTTTCTTCAAACAACTCGACGACACTATCGCTCTTC ATCAGCGTAAGTTAGATACTTTGAAACAGATGAAGAAAGGACTCTTACAG CAAATGTTCCCTAAAAGCGAAGAGGATGTCCCAAAGATTCGTTTTGCTGA TTTTGACGAAGAATGGTACCAGCGTAAGTTGGGAGAAGAATTTGAAAAAA TAAATGAGCGTAATGACGGTTCTTTCGGCAAAACTCATTGGATATCAGTA GCAAAAATGTACTTTGTAGAACCTAATAAGGTCTTATCAAATAACATAGA TACAAGGACATATGTAATGCGAAAAGGTGATATTGCATTTGAAGGACATT CAAATACCGATTTTAAATTTGGGAGATTTGTAGCGAACGACATTGGCCCA GGGATAGTATCGGAATTATTTCCAGTATATCGTCATAAAACTAACTATGA TAATAATTATTGGAAAAATGCTATTCAATTAGAGCATATAATGGCACCTA TTTATTCAAAGTCTATAACTTCATCCGGTAATTCATCAAACAAACTTGAT TCAAAGCATTTCTTAAATCAAAAAATTTATATTGCTGACTTTGAAGAACA AGAAAAAATTGGTTCAATTTTTAAACAATTGGATAATACCATTATTCTCT ATCAAAATAAATTAAATAAATTTGATATTCTCAAAAAAGCTTATTTGCAA ACTATGTTCATTTAA ORF3970 (SEQ ID NO:134) ATAATAGCTCTTTATTCAACACGTGAAGGTTTCGAGAAAAGATATGGCTT TGTTGATGTTGATAAAGATAATAGCTATAAACGTTTGAAGAAGAAAAGTT TCTATTGGTATAAAAAAGTAATTGAAACTAATGGAAATGATTTAAGTTAT TAA ORF3981 (SEQ ID NO:135) CTGGAGGAAAATCAAATGAAAAAAGTATCATCTTTATTAACCCAAGATCA GTTTTGGGGAATTATTGATAACTCTGACAAAGGCAGCAAATTAGAAGAAC TACTAGAAAAGTTGAGTGAGGATGAACTTTTTGGTTATGATTATTGGTGG AACTACTTTCATAAAAAATCTTATAACCAATCGCTCTGGGCTGTTGCTTA CGTAGTATTAGGTGGCTGTAGTGATGATGGATTTGACTATTTCCGTTATT GGTTAATAACAAGAGGTAAGGCTGTATTCACATCTGCTGTGGAAAATGCC GATACTCTTTGCGGTGAATTTGATTTATTAACAGAGGATGAATATCCTGA AAATGAAGAGGTAGCTTACTTAGTGATGGATATTTTCGAGAACAAACTAG GGAAAGACTTTGACGATGCTGAAAATGAAGCAGAGAGTAGAATTGAGTTT GAAGAAGTATCTATGCCTCCAATAGATTTTGAGTGGGATGAAGACGACGA AGATTCTATCAAAAAAGTATGCCCAAACACTTTTGCAAAATGGTGGAATA ACGACAAATTCTAA ORF4017 (SEQ ID NO:136) ACAGGGGGGAGTATCCTGATGAAGTTAGTACAAAAAGTGTATTATTTGTT GTTTAGATTAGTGGGATTTTTACCGCGAAAAAAAGATTTAGTGATATTTG AAAGCTTTTCAGGTAAGCAATATAGCTGTAATCCACGGGCTATTTATGAA TATATGGAGGAGCATAATCCGGAATACGAATTATTATGGAGTGTTAATCC AAAATTCGTGGCTGTTTTTGAAGCTTACGGAGTTCCTTATGTTAAACGTT TTTCTATTAGCTGGTTATTTAAAATGGGGCTTGCTAAGTATTGGATTTCT AATAGTAGACTTCCTTTAGAACTACCAAAACCGAAAAAAACAATCTATGT GCAAACTTGGCATGGAACACCCTTAAAAAAATTAGGCGTGGATATTGATG AAGTGCACATTCCAGGGCAAACAACGGAACAGTACAAAGCTGATTTTGTA AAAGAAGCACAGAAATGGGACTACTTAATTTCTCCTAATGCTTATTCTAG TGCTATTTTTAGACGGGCATTTGGTTTTACTGGAGAGATGATTGAGTCGG GATATCCGCGGAATGATATTTTATTTAGTACCGATAAAGAGCTGAAAATA GCTAATATTAAAAAAGAGCTAAATATCCCAGAAGAGAAAAAAGTTGTTTT ATATGCGCCAACATGGCGTGATAATGATTTTTATGAAGCTGGAAGATATA AATTTGATTTAAAAATCGATATCGCAAAAATGCAAGAAAAATTGGGGAAT GAGATTGTTTTACTTGTTCGCATGCATTATTTAGTCGCGGAACATTTTGA TTTCACGCAATATGGTGATTTTGTCCGCGATGCTTCAAACCATGAAGATA TACGCGATTTATACTTAGTGAGTGATTTGTTGATTACTGATTATTCCTCT GTATTTTTTGATTATGCGAATTTACAGCGTCCTATGCTTTTTTATACGTA TGATTTGGCGGAATATCGTGATACGTTACGTGGCTTTTACTTTGATTTTG AAAAAAATGCTCCTGGTCCGCTTGTGGAAACGAATGAAGAATTAATGAGT GAACTTGAAAAAATGCTTGAAAATCCACCTAAAATAGAAGACAGCTTTTT GGAGCAGTTTTGTACTTGGGAAGATGGTCATGCAGCAGAGAAAACAGTGA AAATCGTTTTTGCTGAAAAATAG ORF4018 (SEQ ID NO:137) GTGGTGGGAATTTTGAAAGAAGTAGCAATTTATATTTATATGCTTGCTGT TAAGATAACTGGCTGTTTGGCGAGGATTTTTCCAGTTAAACAAAAAGTGG TACTGTTAGTTAGCTTTCCGGAAAATTCCACTGCAATTATAAAGCAAATG AACGAAATGAAAGTTACGCCAAAAACGGTTGTTTTCTATGATCCAAGAGT GGATGTGACCGGTTTTAATTTTGATTTTATCCAATTAAAGCCAAAAAAAA TCAAGCACTTTATCTCGTTAATGTTCCATCTGAATACGGCAAAAGTTGTC ATTACGGATAATTATTTCGTGGAATTAGCTGGATTAAAAGAACGTAAAAA TGTGACGTGCATTCAAATTTGGCATGCGAATGGGGCATTGAAAAAATTCG GCTGGGAAGATAAAGCAGCGCAAAAAAGAAGCGCGCGCGATAAAAAAAGA TTTCAAGAAGTGTACAGATGTTTTTCAAAAGTGCTCGTCGGATCGGATGA AATGGCAGCAATTTTCCAAAGGTCGTTTTTACTAGAAGATTCGCATATGT TGAAGCTAGGAATTCCGAGAACGGACAATTTCTTCAACCAACAACAATTG AAAGAAAATGCCGAAAGGACAAATACCAAATTACATCTTTCCAATAAAAA GAAATTATTATATGCGCCGACGTTCCGCGATGAGGAACTTCATAGTACTA CGCTTCATTTAGATATCGCGAAGATGAAACAAGCACTCGGAAATGAGTAC CAATTAATTTTAAAATTACATCCATCTATTAGTAATGATTTAGATGAAGT AGTGGATGATTTTGTTGTCTATGCGGATAAAGAAACGCCAATCGAGACGA TACTACCAGCCGTAGATATATTGATTACTGATTATTCATCTATTCCATTT GAATTTGCTTTATTAGAAAAACCAATGATCTTTTTCACGTATGATTTAGA GGAATATGATAAGGCTAGAGGTTTGTCGGATGGCTTTTTAGCAACGATTC CGGGGCCATTCGTTCATACAACAGAGGAACTAATACAACTAATTGAGCAA GAAGCATTCGATTTAGAAATGGTTCGTGCTTTTGCGGCGAAATGGAATAA ATATTCAGACGGGCATTCTAGTGAGCGCTTCGTTTCCTTTTTGAAAGAAC AGCTAGAAAAGTAG ORF4100 (SEQ ID NO:138) ACAGGAGGTACTGATATAATGAGTTATTTATGGACAAGTATTAAAATGCA ATTTAGAATTCCAGTATCTGTGTTTTTCTCATTATTATTTCCACTAATCA TGATGTTCGCTATGGTTACTTCTTATGGAAACTTTGATATTGGTGAAGGT TATCATTTTGTAGATAAATATTTTTTGATTAGTACAGGGATGGGCATGTT ACCAATAGCATTAATCAGTTTTCCAATCTGGCTTGGTGAAAGTGTTCAAA ATAAAAGCTATAAAAGATTAGAATATTTTGGATTGAGTGCACAGAAAATA ATTGTTTCAGATGTATGTTCTTATATTTTGCTAACAGCCTTAAGTATTTT TGTCAATATACTGTTTGGCTACTTGGTATATGGACTACATATCCCAGACT GGCAATATTTTATTGCTTATGTTTTGCAATGTCTGTATTGTAATCTAGTG CTTTTGATTTTTGGTGCCTTGCTTGCTTTAATTATTAAAAATCCCCGGAT ATTAATGCCAGTAGGAATGTGTTTATTATTTATGTTTTATATTTTTACAG GAACATTTTCATCTTTTTCGGAACTTCCTAAATCATTTCAAGCAGTTGGT AATTTTTTACCTATGAAATATATAATGAATGATTTATTTAATGTTTGGAC ACAAAATAAATTGTTCATCTCTAAGTTTTTAGCTTTAAACACGATATATG GAATCATCTTATCCTGCGCACTAATTGCTTTTTTGTTGAGAAGCAGAAAA ATAAAAATTAAATCATAA ORF4101 (SEQ ID NO:139) AATGAAAAAGGGATACATTTGTGTCCCTTTTCAATAAGTTATGAGGTGCA TGTGCATATGAATAATATTTTGGAAACGAAAAATTTGAAAGTTACAATAA ATAATAAAGTAATTCTATATTTAGATAAAGAAGTTTGTATTTCAGAAAAA GACAAAGTTGCCATTCTAGGAGACAATGGAGCTGGGAAAACCACGTTAGT AAATAGTATTCTTGGTGAAAAGAACTCTTCTGGAGAAATTACCAAAAAGT TTAAAAAAAATGACTGTGGTGTAGTGTTTCAAGAAAATGCATATAATGAT TTGATGAAAGTTTATGAATTGATTACTTTAGTTCTGCCACATCTAAAGAA AAAAGAGAGAGCGCAGTTTTTACACAAATATGAACTTGAAAGTTTGAGAA AAAAGTACATTAAAGACTTATCTGGTGGAGAAAAACAACGACTAACACTA TGTTTAGTACTAGAAAGTCATAAGAAATTATATATCTTTGATGAGTTAAC TTCAGGATTAGATTATAAGAAGAGACTAGGTTTACTTGCTTTGATGAAAG AAAAAACTAAGGACGCGACGGTGATAAATATAACGCATTACTTTGAGGAA GTTGAAAACTGGGCAACGAAAGTTTTGATTCTTCAAAAAGGAATTTTACT TTTTTGGGGAACAATATCAGAATTTTTCTCTAATTTTCCTCATTATTCTG TTATTAAAGTAGATCAAATCGAACTAACAAAGATAGATGAAACAGATATG ACTTTTATGCAAAGCACAGATACAGGTGACGGGATAGCAGTTATTTGTTC GGATTTGCAAATTCAGGAAGAGACAAAGAAAATTTTGGATAAAAAAAACG TCACATACAACACAATAAAACAAAATATATATACAACTTATTTAGTTGCA TATTTGCGCGGAACATCAAGCAGTGAACAGGAGGTACTGATATAA ORF4132 (SEQ ID NO:140) TTACATCTAAGGAGACTAATCATGAAAAGAAAGATAAGTTCTATCATTGT AGTCGGGATAATGTTCTTTCAATCATTAACTACGTATCCATTTATCACCG AAGCCAAAGAAAATGAACAAAAAGAAGAAATAAATAAACCCTCAAAAATA ACTAAGGGATTAACTAATTCCCTAAAATACACTAAGACAATTCTTGAAAC AGGGGACACCTATGATAGTGTATTTCCTGACAGTGCTTTAGCTAAAGTAG TTGCTAAAGAAGCAACGGGGTCAGAGAATACAACTCAGCTAGTAACACAA GCAGACCTGAATAAAATCAAATCTCTCAATGGTTATAATAAAGGAATCAG CGTATTAACAGGAATCGATTTGCTAGTCAATGTGACAAGTATAAGCTTGA ATAATAATCAAGTAACAGACATTTCTCCAATAGATCAATTACCTAATTTA GTAAGCCTATCGGTAAAAAACAATCAAATTAGCAGTCTTATCTTAAATGC GCAAAATCAACTCCCGAAACTAACAACCATTGATATTGAAAATAATCCTG ATCTTAATACTATCGATATCCAAGATCAACCCCAATTGGTAGATGTAAAG ACATCCGGTTATACAGGATTACGCAAGTTAACAACGGTAATTGCCAAAAA CAATCCAGAATTAGTCAATTTAGGCCAATACACTATCCGAAATGTCTACT TTAGCCAAGTAGCAAGTTTAACGAAAGTTGAATTAGTCAATCTCCCTAAG GTAAGAAAAGTAAACCTTGAGAGGAACAGTATTAATGAGCTAAAAGTTAC TGATTTGGCCATTGAAGATCTGCCATTAGGAGAAAATGAATTAACAGATA CTGTATTTGATAACATCCAAAATCTGCCTAATTTAAAAACGTTAGACCTG TCAAAAAACCAACTAGAAGAAGTTGTATTAGACAAAACGGATGTAGAAAA TCTACCCAATTTGATGACACTAAATATACAGCAAAATTTGGCTATAAAAT TGATAAATGTTCAAGACCAACCCCAATTGGTAGATGTAAAAACTTCTGAT TATAAAGAATTATCTGCGTTAACAACAGTAATTGCCAAAAATAATCCAGA ATTAGTTAATTTAGGTTATCCCATTATGCAAAATGTTTACTTTAGCCAGG TGGCAAGTTTAACGAAAGTTGAATTAGTCAATCTCCCTAAGGTAAGAAAA GTAAACCTTGAGAGGAACAGTATTAATGAGCTAAAAGTTACTGATTTGGC CATTGAAGATCTGCCATTAGGAGAAAATGAATTAACAGATACTGTATTCG ATAACATCCAAAATCTGCCTAATTTAAAAACGTTAGATCTGTCAAAAAAC CAACTAGAAGAAGTTGTATTAGACAAAACGGATGTAGAAAATCTACCCAA TTTGATGACACTAAATATACAACAAAATTTGGCTATAAAATTGATAAATG TTCAAGACCAACCCCAATTGGTAGATGTAAAAACTTCTGATTATAAAGAA TTATCTGCGTTAACAACAGTAATTGCCAAAAATAATCCAGAATTAGTTAA TTTAGGTTATCCCATTATGCAAAATGTTTACTTTAGCCAGGTGGCAAGTT TAACGAAAGTTGAACTTGCTAACCTTCCAAAAGTAAGAGCAGTTCGATTG GAACGTAATAGCATCAATCAGATTGAACTAAATAATTTAGTTTCAGTAAA AGACGTGAATCTAAATACTAACAAAATAACAAATGATAGTATAGAGAAAT TTAAAGGCATGCCTATACTAGCAACTTTAAATTTAAACAAAAACCAAATT ACCAATATAAATATGCTTGATGATTTCCCAGAAATGACTACTTTAAATAT TGATTTAAACTCCGTCAGTGTTTTACCAAGTAACCTTAAAACAAAGATGC CAAAACTATCGAGAATTAGTGCATTAAATCAAACAGTTACTTTAGATAAA GCAATTGTAGTGGATGATTCCGATTTAATTATTAATAATGAGATTAGTAA TTTTGGAAAGTTAACCGATCCAAGCCCAATATCAAATTTTGGAACTTACG CAAATGAAAAAATAACTTGGTCGTCTGAAAGAATTAAAAATTTAACAGAG GTTAGTTTTAAGTTTTCTGAGCTAATTAATGTGACTGGTATAGATGGAAC TTTTTCAGGAAAAGTAACACAACCATTTAAAAAATCAACTACACCAGTAA TTAATGCAGATTCCGAAATTCATTATCCGCAAGGGACAAAAAAAACAGAA GCAGAGTTTTTAAAGGATATTCAAGCGCAAACAACGGATGATTTATCCAT TAAAAGCGATTTTGAAATAATGGTGAATCTCAAGAAAGTAGGAAAATACA CAGTAATATTAAACGTAGAGAATATGGATGGAATTAAAGCTAATCCAAAA GAAGTGACTGTTTATATTGATGCTGTACAAGGTGCAAATATAACTGTGAA ATATGAAGACAAATCAGGAAATAAACTTGCAGAAAATAGCATATTAACTG GAAATGTCGGTGAAGAATATAGTTCAAGTGAAAAAGAAATTTTAGGTTAT ACACTAACTGAAATTCCAACAAATGCACAAGGAGAATTTAGTTTAGAAGA ACAGACTGTGACATATATCTATTCGAAAAATCCCGTTCCAGCTAAAGACA TCACGGTACAATATACCGATGAAGATGGAATAGAACTAGCACCAACCGAA ACATTATCAGGTAATGTTGATGAAAATTATGTTACAACAGCGAAGACTTT TACAGGATACGAATTAATTGAAACTCCGAGCAATGCAGAAGGAAAGTTTA GCGAAAATGCACAAACAGTGACCTATGTGTATCGCGCGATTAAAGCAGAT CCAATTTTAGCAAAAGAAGTTACGGTGAACTACCAGGACGAATTAGGAGC TAAAATTAGTGAAACGGAAGTATTAACTGGTGAAATTGGTGAAACATACA CAACAGTGGCTAAAACAATAGATGGCTATACCTTAATTAAGAGCCCTATT AACGCTAGCGGGATTTTTAACGAAAATCCTCAAACGGTTACCTATGTGTA TCAATTACAAAACAACCCAATAACAGCAAATATCACTGTTAAACACTTGG ATGAAAACAACAATGAGCTAGCACCGAGTGAGGTACTAAGTGGAATTGTC GATGAAGCATATACAACTAATCCAAAAGAAATAAAAGACTATTCGCTAGT AAAAGTACCAACTAATGCTAGCGGAAAATTCACGACAGAAGCACAAACGG TGATTTATCACTATAAAAAAAACAGTATACAGACATCATCTTATATTACT GTAAAATATGTAGATGAAACAGGGAAAGAGCTGGCCATAAGCGAGGTATT AAACGGAAACATTAATGATTCCTACGCAACTACAGCTAAGGAAATTAAAG GCTACACGCTAGTGGAAAAGCCCGCTAATGCAACTGGTAAATTTACAGAT CAGGATCAAACTATAAAATATGTATATCGTGCTAATACAGATGAAGTAAA TCTAGACCCAGATGTACCAGCGAGAAATCCCAATGGAGATATTCAACCAA TGAATGGTGCCCAACCACCAATTGAGGTTCCAAAATCCCTGCCTAAAACA GGTAGCCAGCCGGCAAATTTGATCTTTGGATTAGGAGTTTTACTAGTGTT TCTTAGTACCCAATGGCTACATCGAGATAAAAGAAAAAAAGATAAATTTC ATAACTGCTGA ORF4133 (SEQ ID NO:141) CACTTGATGGAAAATTACGTGTCAATAGTAAAAATCGAAAACAATCTTTC CGTGTGCTTTTACAACAGCTCGGAGAAAGTAGTAGCAATTGCTAAGAAAA TGAATGAGATTAACGAAGAAGCTTATATGCATGGTTACAATTGGGAAGCA TTTTTCAACTACTATTTACCTAAATATGCTCCAGATGTCTTAGAAGGAAT GGGCTCTGATCCGGAAGCGGGAATGTATGTGGCGTATTACACGCTATCAC CTGAAACTGAGGCACGAGCAGAAAAACTTGTTCAAGTAATTACGAATCTC ATCGAAAATGAAGAACTACTTTATCAAATAATTGAAAATGAAGGCAATAA TATTAGTTGGGATAATTAA ORF4135 (SEQ ID NO:142) GAGGCAATTATGACTTTTTTAAACACCTTAAAATTAAATTTGGAAAATGA AAAAAAGAGAATGTTATCCGATGCTTTTATGAAAAAACAAGAAGGAATCA TTGTAAACTATATAGTGACTTGCAGTAAGGATTCTGCTATTGGCATTAGT AAAAAGGCAATTGATATATTATTGATAATCAATGAAAATACATTTCCTGA ATGGCCAAATGTAGATAGATGGCTTTCTATTTTGCCAAAATATTTTACGG ATTCTTTTTCAAAATCAAAAATATTGCATAGTGAAGATTGGCTATTTGAA GAGTGGTTATACTGGTTTGAACCTGAAAATAGATTTTGGTTTTTAGGAGA ATTAGATCCTGTTGATAATGAGCATTTGAAAATAAGCATAGTTGTACAAG AACACCCTTTTCCAGTAGAATCATTAGAAGTTCTACTTATGAAGCTAGGA ACAAGCGAATTACATGAAATTGGTATGGAATGA ORF4188 (SEQ ID NO:143) AATTTTAGGGAGATAGATATGAATAAAGTGACGAAAATTGGAGATGTAGC AGAGAAAACGGGCTATTCTATAACTACTATTTCTCGAGCAATTAATGGTA ATCCAAATGTTTCAGATAAAACAAAAAAGAAAATTTTTGCTGCGATGAAA GAACTGAATTATTATCCTAATAATATTGCTCAACAATTTCGAGGGCAGGG GACTAAGATGATTGGTGTTGTGATTTCCTTTATAACCAATCCTTTTTTTG CGTACCTTGTTGATGCGATTGAACGCTATCTATCTCACAGAGGGTATCAG GTTGTCATGTTGCAAACTTTAGAAAATCCTGCAAAAGAATTACAATTTAT CGAGATGTTACAAAAGAAACAGCTAGATGGATTGATTATGGCTAACTTAG AAAATGATACAGAAGAAATTAAATCACTCGTTGAAAGTGGCAAAATTGTT CTTTGTAATCGTTATCTGGGAAATGAAAATTTGACGATTATTAACATTGA TGAAACGAAAGCGGCTTATCAAGCAACGAATTATTTAATAAAGTGCGGTT ATAAACGCCTTGCCTACTGTACTGGTGGTATTAAAAATAAAAATGATTAC CGTTTTAAAGGATTCATGCAAGCTGTAACAGAAAATGGACTTTCTTTTGA TGAATCATTGTATTTTGAGAAGTTATTAACCATTAAAGATGGCGAAGAGC TTCTAGTTAATATTTTAGAAGAGAAATCTACTCTGCCGGACGCAATTTTT TCAAATGGTGATACGGTTGCTGCTGGGATATTATATGCTGCAAAAAAATA CGGGATAGCAGTGCCAGAGGAGCTAGGAATCATAGGTTTTGATAATCAAC CTATAGCGGAAGTTCTGAATCCGGCGTTGACAACTATTGAACAACCAATT AAAGAACTTGGTGAATATTCGGCGCAAGTTCTATTGGCTAATTTACAAGG AACGAGTGTGCCGGTAGCGCCAGACCTTGAAACAAAACTAATAATAAGAG AGACTACCAAGTAA ORF4327 (SEQ ID NO:144) GAGAATGGCAGAAAGAAGAATTTGGCGTTTCTCCAGAAGAGGAGGATGAG ATACTTGAATTATGATGAACGTGTACGAGTTTTAATTGAGCTGAAAGTTG ATTTGTCCGGAAAATTAGAAATGATGGAAAATGAAGAAGAGTTATTATGT AGACAAAAACATGATTTTGTAAGTACCTGGTCAAATGCCAAAACAGAGGA TGCTTACAGAAAATTAAATGAAGCAGTTAGAAAGAAAATCAAAGAAACAA CGGAATATGCAAGAGAAATTGATGAAAAAATTACTGCTCGTATCAAACGA ATTGAAGCAGCATATAAAGCAGAATATCAGAGTAATAGGAGCTATACATG GCGTATCGCAGAAATCGATCCAATTAAATTTAAACAAAAGTATAATGAAC GATTAAATCAGTTAAGCTACTTATCATGTGATGGCAGCGTAAAAACACGT TTAATAAAAGAGTTTCGGCAAAATAATTTCCTGAAATAG ORF4369 (SEQ ID NO:145) ATGGAGAGCGAACTAGAGGGAGGAAACAACATGAAAAAAACACGTGTCAC ATGGGCAATAGTTATTGCTATAGCAGGCTTGTTAGTTTCTGTGATCAGTT TATCAGTAAACATCACCCAGAATAGATATAATGTTCGAGGAGTGGATTCT AGTTCCCAGTGGAAAACTGGATTTCAAAAAAATCAAACTGTTTGTGCAAT AGAAACAAAGAAGCATTGGACAAAGGGCAGTGTGAAGTATGGTGTGAACC AAACTTCTGGAACTGTTAAGACAAAGTATAGTATATACAGCAAAAAAAAA TAA ORF4457 (SEQ ID NO:146) AGTAGAGATGAGATTAACAAAATGAGAGCAGACTTATCAATTATGTGGGT TGAAGATACAACTTCATGGTATACAGAACAAAAAGATCTTCTAAATATGG ACATAGAAAGCTTGGGTATAGATATTGAATTTACTCGTATTTCTACAATT GATGATTTTTATAAATTGGTTAGGAATGATAATACAGGTTTTAGTAAATA TGATATTTTTTTTGTTGATTATGCATTATCCTCTGATACTGAACAAAAAG GAAGTAACATAATTGTTAAGTTAAAAGATATGGGCTTAACAACAGATATT CTTTTCTATTCTTCAAAAAATATAAGAGAAATAAGGGAAATTGTGAAAAA AGATATTGAACAGTTTGAGGGAATATATCTAGCTGATAGGGATAAAGATT TCAGGGATAAAAGTTTTCAATTAGTTGAAAAAAATATTAAATCATTATCA TCTATAAAAAATATTAGAGGTCTATTAATGGATCAAACTTCTGAAAACGA TTTTATAGTTAAATCTTATATTTCAAAAGAAATAAATGAACTTTTACCTG AACAAAAAGAAAAAATATATAAATGGTTTGAGAAGGAAGTAGATAAAAAT ATAGAAGAAGTAACGAAAACAATTAAAGGTTATGTAGAGAGAAAGCCCAG TACTATAGAAAAATATTTAAAATTACCAAGTTATATATTACCAGTTAAAC TACAATATAATTTATTAGAAGAAATTATAAATATTAATGGAGTAGAGACT TTTGTTGATTCAACTATTGATTATTATTTGAAAAAAGTTGTGAGTAATAG AAATAAATTAGCTCATAGAAAATTAGTTATGTGTAGGCAGCAACAACATT TATTGCAGTATAATAATATTAATACGTTTCTAAATGATGATTCTAATGTT TGTGATAATCATGAAGGAGATGTAGTTTCAATAGATGATTGGATTCAACT CAGAGTTGAAGTTAAAGAATATGGTAAGTTATTTGATGATTTGTGGGAGA AAATTAAGTCGTGA ORF4507 (SEQ ID NO:147) AAAGGAAACAGCAAAATGATCGACTATGAGAAAAAAGGCTTTTTTAACAT CCACACATTGGTAAATAAAGATAATGCTAATATTTCTAATAGTGATAATA AACATATTTATTCCCAGCTGATGTCTGGTAATGGCAATTCACCAATGCTA GGTTATTTATTAAATATGAATAAACAAAACTTGAATGACTTCAAAAGTAT CATGTTTTATAATGAATCTAATCTAGCTTCTTTAATTAACGAGGCAAGAG AAATGGAAGAATTAATAGATAGCTCAACTCTTTTTTTAAGTAAAACAAAT AAAAAAATTAAAACCCATTTTTCTAAAGTGCTTGAGCAAAGACATAGTAC AAGAAATTTTGTATACGAAACCATGGATTTATCAACATTCTCAAATATCA TACAGTTTTCTTTTGGCCTTAGTACAAGAAAGTTGGTTTATAACGACTTA CAATCAACCACCAGGCATTATTCTTCTGGGGGCGGTTTATATCCAATTGA TGTTTTTTTGTATATAAATAATATTTCTGGAATTGCCAAGGGTATATATA AATATCAGCCATACACGCATAGCTTGCATCCTCTAGATGTAGATAAAATT GATGTAGAGTCGTTTTTCGTAGGTGATAATATTGACACTTCTAATATGAA TTTTTGTGTTTTCTTTGGATACTCTATTAATAAAAACTATGTGAAATATG GAGAACTATCTTTACTGAATACGTTTGTGGAACTCGGAGGAATATCGCAC AACTTTGATTTAGTCTGTCATTCGGTTCACTATACAAGTTGTCCTATTGC AGGTTTTAACAAATCATATTTGGAAAAGCTTTTATATTTAGATGGAATAA ATGATCACATTATATTTTCTAATATTTGTGGAAAGGAATGA ORF4563 (SEQ ID NO:148) TCTATGAAAAAAAAATTTAGTAATCCCACGTTTAGAATTATTGCATCAAT TGTTCTAGGGATTTTAATAGGTGTTCTTATTTGCTTTGTGGCTATTGGTT TAGGTTATATACACATGAATGATGGCACATTAAAAGAGTATAGTGTGAAA ATTTTCGGACTAACTATTTTTGATATTAAAAGAGTTGGTAGTGAGATGGT GGGAACACCTAATAACACTAGCATGATGTTTATAGGGGTTATTATTTCTA TGATACTAGCTATTGTTGTAGAAATTATTGTTTCGTTAAAAAACAGACAT AGAAAGGAAACAGCAAAATGA ORF4578 (SEQ ID NO:149) ATATATACAATTTTTGATAATTATGCTATATTTGGAATGCACATAAATAA TTTACATAGGAGAGAGAATGAAATGAAAAAGAAATTAGTTGTTTTAGGGT TAGCGGGTGCAATATTTTTATCAGGAATGGGAATCTTAAACGTAAGCGCA GCAAATTATTCGGATACAAAGTTTAGTTTTACACTAGGTAAACTTGGTGC AAATGATTACACTGGTTCTAGACAAAAACAGAACACTACATCATCTTATG TGAAATTAAATTCAATTGGAAAAGGAACAATGGATACATGGCTTTTAAAA TCTAACGGAGCTAGCGTTCGAAGTAAATATGTGACTGTGAGGCAAGGTGA AAGCAAAAAAATTGCTAACTACGCTTATGAAGATTATGGCAAATGTAATG TTAAATTAGCTGCTGAAACTAGTAAAACTCAATTTGTTAGAGTTACTGCT ACAGGCCTTTGGAGTCCAGATAGTATTTAA ORF484 (SEQ ID NO:150) AAATCAATGAAAGCATTAGAACGATTTCTGTCAAAATGGTTATTACCATT TGCAAAAGTACTAGAAAGTAACACCCAGATGAAGGCAGTACGTCAAGGAA TGATGGCACTTGTACCAATTACTTTAGTTGGTGCAGTTCCCGTTTTATTC CAACAGCTAGGCGGGATTCCGAAACTACCTAGTTGGATTGCAGCGGTTTC CAATTATATCAATAACATCACTTCTCCAATATATTTTGCCACTTTTGGAT TAATGTCCGTATATGTGGCGGTTTTTGTAGCATATTACTATGCGAAGGAA CGCAATTTATGGGATATCGGGGCGATTGTAACAGCCTTAATGAGTTTTGT TGTCGTTGCAGTAAGACCACTTGAATCAGGCGGGAGCGATGTAGCGTATC TAGCCGGTGAAGGGATTTTTGTTGCTTTAGTAATTAGTTTATTGTCTGTC GAAATTTTACACATTTTTAAGAATAAGTTGAAATTCACGATTAATTTAGG ACAAGGTGTTCCAACGCCGATTTTACGTTCTTTTGAAAATTTATGGCCAA TTTTATTCTCTGTTTTAATTATTGCTATTTTAAGTTTTGGGATAGAAACA TTAAGTGGTATTCGTGTAGTTGAGTTAATTCAAACACTATTTTCTCCACT GACATCCCTAGTAAACACATTACCAGGTATTATGTTAATTATCTTTATCC AACAATTATTATGGTGGTTTGGTATTCATGGCTATTCTGTTATGGCGCCA GTTTGGCTCAGTGTAGCGTTCCAAAACGTGGATGCGAATGCAGCAGCTCT TGCAAAAGGAGAACCACTTTCTTCTATGCTGATTTTCACTCCTGACTTTA TGTGGAGTATTGTAGGTGTAACTGGGGCTGGGGTTACAGGAGCACTCGTT GTCATTATGATGTTCTCCAAATCAAAACGATATAAAACACTTGGTAGACT TGCTTTAATTCCAACCTTCTTTAGTATTAATGAGCCAGTAATGTTTGGTG TTCCAATTGTGTTAAATCCACGCTTCTTTATTCCGATGATGCTTGCACCG CAAATTGCTGCTTTGATTGGTTGGTTCTCTATCAAGCTTGGATTAATGAA TCCATTTACGATGGTTTCTCCATATGTACCTGTTCCAATCGGTGCTATTG TCGCTTCATTTGACTGGAGATATGTTATTGTACTTGGTCTTATCTTGGTC TGTTCGGCCCTTATTTACTATCCATTCTTTAAAATTGCTGAAAAAGAAGC TATTTTACAAGAAACGAGTGGAGACCAAGAAGCTAGTTTAGATGATTTTG ATTTTTAA ORF485 (SEQ ID NO:151) GAAAGGACGATAGACATGAAAATTATGTTAGTATGTTTTGGCGGATTATC CACTTCCATTTTAGTAAAAAAGATGGAAGAGGCGATTGCGGCATCTGAGA AATTTAAAGATAAAGGAATTACGATTGAAGCTTGGGGGAAAGATGAGTTT TCTGATCATCTAGATAATGTTTCTATTGTCTTACTTGGCCCTCAACTCTC AATGGCTTATGAACAGGTAATCGAAGCGACAAAAGAACATGGATTAAATG TTCCAGTCGAAGTTATTGATAAAGAAGATTATGGCAACATGAATGCAGTA CCAATTCTAATCGCTGCATTTAAAAAGATTAAAGAAGCTGGAACGAATAC ATTTAAGACGGAGGGAAACTAA ORF577 (SEQ ID NO:152) CACATGAAAATACATGCAAAAGCAAAAAAAATCTTAGTGAGCCTGATAGC TATTATGTTATTCCTTTCACTAATACCTGGTTATGCACCAATGGCGGAGG AGACGTCAACTGGGGTAGAAGTACCAGAAAAGAAAGCGGGAGAACAAGCA CCAACAGAAGTGAAAGAAGAAAGAACAGAAAATGAAGTGGTTTTTAATAA CCACGACGGGAGCTTTACAAAACAAATCTTTGCGGATTCTATCAATATGG AAGTTGATGGCGAGATGAAACGCATCGATGCGAATGTGGAGAAAGAAGCA GATTCTGACATGATTGTTCCAAAACAAACTCCATTAGAACTAGGCTTCTT AGACAAAATGGAAGACGGCGCATATCAGAAACTAACAAAAGCTGGCGCAG AAGTTACTTTTCGCTTAAAAGGAGCACGTACAGGCGAAAATGAACAAGCA GTTACAGACCAACCAGCGACCTACAAAGAAAATGAAGTTACTTATGAAAA TGTATTTCCTAAAACAGATTTACGTCATTTAACTTTTCCACAATCAGTAA AAGAAGACATCGTACTACATGAACCTAATCAAGTAGATACGTATGTTTAT CAAATAGAAACAAAACTTGGTTTAGAGCTGGCAAAGAATGGTGATGTGCT ATTCAAAAATAAATCCGGTGAAACAATGTATACGCTTCCGAAACCAGTTA TGACAGATTCCAATGTCGGCGCTGAGACCGGGGAAGCAGCGTTATCCGAG AATGTTTCCTTTGAAGTGAAACAACTCACCAAAACAGTCTATGAGTTACA ATTAAAAGTAGATACAGCATGGCTAAATGATGTCGCGCGCGAATATCCTG TCTATATTGATCCATCTGTCCGGTTAGATGAAGTGTATAATGCCAACATC AATTCAGCAAAACCAACCGAAACCAATATCGGAAGCAAACTTTGGGATTC TGGCCAAAATGCTTACACGTTAAAACTTGGTAAATGGGACAATTCAACAG GAAATAATGCCGCCTATTTAAAAATGGACACGTCTACTTTAAATAAAGCG ACGATTTCTAAAGCAACGCTAAAAGTGTATAACATTTGGCATATGTCCCC AACAGTTAAAAATGATCTTTGGTACTATGAATCTAATGCGAACTGGTCCC CATGGCAAGTGACATGGAATACAGCTCCTGCAACGACACGGATTGGAAGC GTCAATGTCGGCCGAGGTGAGTGGGCGAATTTAGATGTCACTAAAACAGT TCAAGCATGGGCAAGTGGCGTGCGACCAAATAACGGTTTCCGTCTAGCTA CGAACATCGATCAAAACTATTGGAAAAAATTAGTAGCAAGTGAAAATAAT AAAAACTATCCTTATCTAGAAGTAAATTATACGTATGCTCAACCGGAAAA ACCTACTGTTAAAACGAATTCAAATGGAGTAGGAACTGGAACAGGTTACA TGGATTTATCTTGGAAGGCTGTTCCTGGTGCAACGAGTTATAATATCGTT ATTTCTAATGGATATAACTACGAATATATTAATACAAAAAGCACCGCAAC CACTTGGAGCACTAAAGGGAAGAAAATTTTCCCAACAAATGACGAAATCG CTAATGGAGAATTCGAATTCCACCATGATGGCAAAGGAACCGAATTCGCT CTTGATCCGCGAGCGCAATATGAAAATGCGTTTCAAGCTGGAAGTACTTT TGGACTGCGCAATTTAACGCGCTATTTATTCAGAGTGCAAGCCGTTTTCC CGGGTGGAGAAAGCCCGAATTCCGACTTAGTATTTGCCTATATGCCAATC GAAAAACCACAACCCCCTGCTGCGAAAGCATATTCTAACTTAGCTCATAA AGAAACAGGATACGTGGAACTTAACTGGGAAAAGAGCCCAATGGCGGATG GCTATAAAGTACTTGTCTTCAATGGGAAAGCCTACGAAGAATACGATGTT GGCGCAGAAACAAAGTGGACCACCCAAAATAAAGGGATTTGGCCAACCAA AGAAGAAATTGCAGAAGGTAAATTCGCTCTTCATCATGACGGAAAAGGCG ATGAACTAGCAAAAGATCCTTCTCCAGTTTATACCAATTCTGGCGGTAAT TATAAAGAACGAACAAACTACTGGTTCCGAATTGTTGCGTACCAAAAAGC GGGAAATAACGCCACAAGTATTCAATCCGAACCAGCGACACCATCCCTTC CAGAAGTAGTAAATAAACAGCTAGGAATGGTAGATTACTGGACAAGTGTG CCGGTACGTGGCGGCGAAGTAAACGCTACAAATGGAAACTTTTTATTCCA TGAAACAGATTTTAACTTAGAAGGCCACGGCCCGAGTATCAATGTCGACC GTACTTTTAACAGCCAAGATGACGCAACAGGCATTTTTGGTAAAGGCTGG ACAAGTACGCTTGAAGAGAAACTTATTGAAGAAGAAAACGGAAATATCGT ATGGGTGGAATCGGACAAGAAAGTCCATCGTTTCACTAAAAAAGGCGATA AATACGTGGCACCACCAGGCATTTACTCCGAGATTACTAAAAACGCAGAT GGCTATTTGAAAATAGAAGAAGATAAGTCAGAAACGCGCTTTTTAGCTGA TGGACGATTAAAATCCGAAAAAGATACAAAAGGCAACGAATTAACTTACG AATATACTGACGGCAAACTAACAAACATGCGCGACGCTTCCGGACGTACC GTGACTTTAGCGTATGAAGGCGAGCTCGTAAAAGAACTTGTCGGACCAGA AGACCGTAAAATCAGCTACACGTATAATGACAAACAAGAGCTAATCAGTT CATCCACTGCCCGCGGTAAAATATACTGCTATGGCTACACAGATGGCTTA TTAACATCGATTTACGATCCAAAACATACAGAAGAAAAACCATACGAAAC AACCTTTGCTTATGAAGAAGAGAAATTAACAGAAATAACCGATCCGGTCG GCAAAAAAACAACACTTTCTTATGACATGGAAGAGCAACAAACAACTTTA ACAAACGAGAAAAAGAAGAAAACCATTTATTCCTACAATGATGCTGGAAA TCCAAAGAAAGAAATTGTGGATGCAGATGGTCTCAAACTCACAACGACCT ACACGTATGAATCAAATAACCTAGTAAAAGAAGTGAATCCTAAGGGACAA GAAGAAACATATTCTTACGATGCAGATGGTAATATCACGCAAGCGACAGA TGCTTACGGTACAGAATCATATACCTACAATGGAAATAACGATGTAACGA GCGCAACTGACACAGAAGGACGCAAAACGACGGTTACTTATGACGGAGCA GATGCGGTGTCAGAAACACTTGCGACAGAATCCCAAGTATCCTCTGTAAC GCAGTATGACGCCTATGGAAATCCAATTCGAGGTAGTGGTGAACTTTCTT CAGCAGGTAACTTACTTCAAAACAGCGGCTTTGAAAAAGGAGCAGGAGTT TCCAACTGGACACTGATTCAATCTGATGCAAAAGGAAGCATGACATTCGA TAGCACTCAGTCAGCTCCAGGAACACTCGGCGGCAGCGGTTCCGTTAAAC TAACGAGTGAAGCAAATTCTACCGTAAAAGGCTATTCATCCGTTACTCAA CGCGTTGATGTAGAACCAGAAACAACGTATACATTTAGCGCCTGGATTAA AACATCCGGAATGACAAACGCCGATGCAATTCTCATTGGACGTTTACAAG ATGCGAATGCAAAAGATATTACCGATGCTGGCGTATGGCAATCCAACCGT GCGACATCCATCAAAAAGAACGGCGGCTGGGTAAAACGTCAATTAACCTT TAAAACATCTAAAAACACGCGCCAAGTCTTGCTTTATTTGGACAACGAAC AACCAGCTCCGCATAAAGGAAAAGGAACAATTTGGTACGACAATGTTCAA TTTGAAAAAGGTAGTGTTGCTTCCAGTTACAACCCGGTAGTCAACAGCAG TTTTGAAGAGCACAATGGAACGCTTCCGACTGGCTGGGCACGTTCAGGAA ATACCGCACTTACACAAGCAAAAGTAGTCGATAATGAAAGCCATAGCGGT GATAGCGCTGTTTACTTCGAGCGAAAAGCAACAAGTGAAGCCTACACGCA TATTGTCCAAGATGTACCAGTAAATCAAAAAGAAGCCAAAGCATTAACAA TTTCCGCACTATCCAAATCAGAAGACGCCAAAGCAAACGGTTCTGTTGCA ACGATGTCGAACGATTATTCGATATGGGGAACAATATATTATCAAGATGG CACAACTTCTTCCGTACAAGGTCAATTCCCACTCGGAACGAACGACTGGA ACCGAAGTGCCGTAGTTGTTAAACCGACTAAGCCAGTCAAAATGATTAAA GTTTACACCATGTTCCGCAATGGTTTAACCGGAAAAGCTTGGTTTGACGA TGTACGTGTCATAGAAGGCGAAGTATTAACAAAAAATGAATACGACGCTT CCGGCAATTATGTAACAGCTAGCTATGACGAAGAAGGCCGCAAAATCAGC TTCACTTACGATATTTACGGTAACACTACATCCGAAACAGACGAAAAAGG CAACAAAAAAACTTTAACCTATGATGCAGACAACGCACTTATAGACACAA AACTAGCGAACGGCACATCCGTAGCCTATAAGTACGACGACAATGGCAAC ACCACCGAAAAAAATGTCACCGCATCTGGCAAAACGCAAAAAAATATCTA TGAATATGACGTAGATAACAAAATTACCGCATTTACCGATGCACTTAATC GCACAATCAAGTATGAATACGATGCAGCCGGTAATGAAACAAAAGCAATC ATGCCAAATGGTCGCGTAACCGAAAGCACATACGATTCCGCTGACCGCTT GGACGGGATTAAATGGAATGATAAACTAGCATTTAAATTCCAATACGATC CAAACGGCAACCAAACAAAAGTAACCGACGAAATTAACAGCATCGTTACC GACAAAACCTACGACGATGCCAACCGAATCACCAAAGTAGCCGAACGAGG TGGTGACGTAAGCTACACTTACAAAGATAAACCAACAAAAGACAACAAAG GAAAAACAGACAAAGTCGGAGAAGTAGCCATTAACCACGGCGACTACACA GCAAAAACAAGCTACACATACAACGACTTAGACCGGAATACCCGCGTAAA CGACGGAAGCAAAAACGCCTATTTCGAGTTTGACGAATTTGGAAACATTA ACGTCTACACAGCAGGAAACGGCACCGCAGCCAACTACACCTACGATAGC ACCCAAAAAGTCACCAACGCAGCTATTAGTAGCGCAAGCGGCACCCAAAT TTTAGACGAAAACTACACCTATGATGCAGCAAGCAACCGTACAAGCATCG ACAACAAACAAGACGGAAAAACAACCTACGAATACGATGCAGTCAATCAA CTAACCAAAGAAACACTACCAGACGGCACCGTAAAAGCATACACCTACGA TGGCTTCGGAAACCGCACACAAGTAGCAATCAGCGGAAGCGAGACAAAAA CAATTGCCGCAAGTTATAATGATGGTAATCAACTGGTTTCGTGGAACGGA GAAGCGCTGACGTATGACGCCAATGGTAACCGTACAAGCGATGGCAAGTA CACGTATACATGGGATACCGGCGACCGTTTAAGCAGCATTACGAAAAAAG GCGAGAGCAAGCCGTTTACGAGTTATACGTACGATGATGATAACCGCCGC TTGTCGAAAACAGTCGATGGCGTGACGACGAATTATCATTATGATGGCGA TAGTATTGATGTTCTGTATGAGACTGATGGTGATGGAAAAGTAGTTCGTC AGTATGTTTATTCGGATGATAATGTTCGTTTAGCGATGAAGATGAACGGC AAAACCCTCTATTATCACTATAATGCGCATGGCGACGTAATTGCGCTCAC AGATGAAGCAGGTAAGATTGTCGCAGAATATGCGTATGATGCTTGGGGAA ATGTGCTGAAAAACACTGCCTCTACAGAAGAAGCCAAAGCCAATCCGTAT GGTTATGCAGGATACACATATGACAAGGAAATCGAACAATATTACTTGAT GGCGCGTTATTACGAACCAGAGCAAGGCGTGTTTACCGCATATGATCCAG ACCCGGGCGATGAAGACGACCCGCAGACGATGAATGGGTATAATTATGCG AATAATAATCCGGTGATGATGGTTGACCCTGATGGAAATTGGGCATGGCT TATCCCAGCTGCTATGGCTGCCGGTAAGTTTATTTATAAGTTTAGAAAGC CTATTGCAAAATATGGTAAAAAAGGTGCCAAATGGGTAGGGAAGACTGCT AAAAAGGGCGCTAAATGGGTAGGGAAGACTGCTAAAAAAGGTGCTAAGTG GGCGCGATCGAGATATAATTCTAAGAAAAAAGAATTTACAGTTACTAAGA ATTGGAAGGTAGGGCTTCCTAAGAAAAGCCAAGGAGGAAGGATTTTTGCT ATAATTAACCGTAAAAAAGGGAGGCTATTCGCTTTAGATTACGGAAAAGT TGGTGGAAATCAAAAAAAATATTTACATGTCCACTGGAACTACAAACCAA AGCACTATATAATCTATCCAAGAAAAGGAAGGGGAAAATAA ORF633 (SEQ ID NO:153) GATGACATGAAAAAATTTATTCTAGCAAGCCTTGCATGTACGACTTTGAT TAGTTTTAGTCCTTTGGTAGGACAAGTCGAAGTAAGCGCTGCTACAACAA ACATTGCCACTGCCCCAGAAAAAAATTTACAAGAAGCTCCTCCAGCCACG GTTGATCAAATTTTCCCAGATGATGCTCTAGCTTTTAAAGTCGCACAGGA ACTAGGTGTTTCCGAGGATACAGTCGTTACACAAGAACAACTAGATACTA TCGAAACAATGGTATATGTGGATTTCGGTGTGGAAGATTTAACAGGCATG GAATATTTACACAACTTAAAATTTGTAGATTTAAGCCAAAATAAAATTAG CAACTTAGAGAATCTCGCTAATTTAACAGAATTAGAAACGGTATCACTTA ACTACAATCAAATTACAGATATTACTCCACTAATGAACTCACCTAAATTA TATAACTTAGAATTAGGCGTTAACCAAATCTCTACTTTACCATCCTTCGA AAATTTAACTAATTTAAGGATATTAAATCTAAGTAGCAATCAACTAAAAG ATATTTCGGCCCTAAAAGATACTCCTCAATTAACTAATTTATCTATTTCA GCAAATAATATATCAGACATCAGTGTCCTTTCAGAATGCGATAATCTCCG AGTTTTTTATGCCGAAAGCAATCAACTGACTTCTATTGAGTCATTAAGAA ATAAAACAAAACTAGAATACTTCGATGCTAATTTTAATCAAATTAAAGAT GTTACACCTCTCAGTACCATTCCAACAATTAGGTCAATAAAAATTGAAGA AAATCAGATTAGTGATTTCAGCTCATTGGCAGGTCACCGCTTAGAATTGT TTGATGCTACTGGACAAAATATATACCTTCCAGATGTTGCGCTCGGCGAT TCCACTAATATTGTAATGAAAGATAATCTCGGAGTAACATTACATGATTG GGTTTGGTACACCCCAGGAACTTACCAAAATGATACACTTACTTGGGAAA ATGCAGGCGATAATTCCGCTTACTTTTTAAATAATCAATATCCAACTTAC CCTTCTGTCACAGTGACTGTCTATCAAACAGTCACTCCTTAA ORF653 (SEQ ID NO:154) AAATTAACTACGAAAGAAGGAGGGGAGCTGATGAAAAAGTTTTCCATGCG AGTGGTCCTTATTATTTCTGTGCTTTTTATTGCTTTTGGGAGCGCTAATG TTTCTATCGCACAAGAAAGGGACACAACGAATAAGCTTCCAGAAGAGGAG CTAGGTTCTCTGGATACCTCTAATATCATTGCAGAAGAAGTTGCGCAAGA GAAACCAGCAGAGGTGGAGCAACTAGAAGAAATCCCAACTACGGATGAAT TGATGCAAAATCCAGATGTTCTTGAGAAGTCTGTTGCCGATTCGGATGAT CCGGATTTAACAGTGGTAAGCTCAGGTGATTTTTGGACGATTTATCGTAA TACTGTGAACAATGAATATAACTTGCGTATGTTTGGTAACGTGCCAAGCA GTAGACCAACCGCTTGGAATAGTTATTTGAAAAGCATTAAACATATAGAG ATTGAAGAAGCTACGCTGACAGGAAGTTTTGCATCGTATTTTAGAGGTAC TGATTTCCCAGTACTTGAAAGTGTGAGAATTGAACAGTGTAATTTGTCTG GAGTGACGTCTTTTGAAATGGCATTTTATAATTCAGGAATTGAAAAAGTT ATTATTAGGGATAATGATTATCCGAAAGCACCATCTTTACTCACTGCTAC GCAATATATGTTTTCCTTATGTCGTAATCTTAGTGAGCTTGATTTGAGTG GCCTTGATACGAGTGCTGTAACTAATATGTATGCCATGTTTCAAAATTGT ACTAGCCTTGAAGAGTTAGATCTAAGCAACTTTGATACCAGTTCAGCTAC TAATATGTATTCCATGTTTTCGGGTTGTAGATCACTTGAGAAATTGGATG TAAGCAACTTTGATACGAGTTCAGTTGCACATATGCAGTTCATGTTTGAA AAATGTAGTATCCTTGAAGAATTAGATCTAAGTAATTTTGATACAAGTTC AGTGACTAATATGTCTTACATGTTTCAACTTTGTCCAGCGTTAAAATCTT TATATCTGGATAATTTTACGGATGCAGCAATTATGACAGGTATGTTTGCT GGAACCACCTCCCTAACCTACTTGTTTGTCAGTCACAATTTAAGTACTTT TAATAACTTAGAAAATACAAGCTGGTATGATGAAAAGAATTGGGTGCAGT TTTCGAATCTCTCGCAACTACAGACATATCACAGGCAACAAAGTGAACCT ATTGGCTATAGAAAAGGCGCTTTCCTTTCTCTAACAATGGATGCGATGGG TGGAGAATTTGAAGATGCGGAAGAACAAAAAGTACAAAATAAAATTTCTG GGGAGTACTGGGAAGAAGTGATTCCAGTAAAAGAAGGACATTACTTTGAC GGGTGGTATCTTGATCAAAATTTCACTAATAAGTTTGATTTTTCCTTGCC TGCTGCTGTATCTACAACTATTTACGCCAAATGGGTAGAAAACTACACGG TGATTATTCCAGCGTCTATTTCCTTAAATGAAGCTTCCGAATTGAAAGTA CAAGGGATTAATCGAGGGAGTAAAACTTTATCCGTAGGTTTGAATTATGA GGAAACAACCATTTCTGAGAGCAACAAGCTAACCTTGTCCAATACGGCAG ACACAACAGTCCGATGCTTGGCACCAATGAGTTGGGACGGGTCCGAAACT AATCCGGAAAAAGCGATTTTAACCCTTGCCCCAGGTTCGGAAATAACAGA AGGCGATGCAGTTATGGAAATAAAATCCCCAGAAAACATCCAGGCTGGAA AATATACGGGGAACGTCGTATTTTCGATTAAGTATGAATGA ORF660 (SEQ ID NO:155) AAAAACATAATAAGGGAGCGAGATAACCATGAAAAAATCATTATAGTACT AGCATCAGTTATGTTAATGTCTCTTTCGGTTCTGCCACTGGCAACTTATG CATCAGAAACAGAGAACACTCCTACTGAATCATATGACGGAGAAAATTTT ATAGCAACCCAAACAGGTAATACTTTAGTTATTGAAGATAAGAAGACGGG CGAAACTGTAAAAATTGAAATGAATGACGAAGAAAACGGGGTAATTACAT CTGATGATGGTACAATAGAAAATGTACATAGGGATGAAGAAGGTAACGTT TATGTAGATAATGAGCTTGAACTAGAAGCACCTCCTTTAGACATTGAAGA TGGCATAAATATCGCCACTCAGCCTCGGTTACTGAAAGCTTCTAAATGGA TATATGTTCAAACAACTAAGTATAATACAACCACACAAGGCAATATGAGA AGTCTTGCATTGGGGATTCTATCATTCATGCCAATTACAGGTCCAATCTT TGGAATAGTTGCAATTATTGATGCTGCTCGATCAATGGGGGCGAAAACAT TATATGTTAGAGTGAAACAATATCGTACTAGTGGTTATCAATTTTATAAG TATGATTCTTATTATTATGCCAATGCTAGTTTAACTAAGCTAGTTAAAAA AACATCCCAGACTAAACGAATGTGGTAG ORF72 (SEQ ID NO:156) GGAGGAATAACTTTGAAACAGTGTCCAGTTTGTGAAAATTATACGATTGA AGCTAATTACGATATTTGCGAAGTATGCTACTGGGAATATGATGTGGTAG CTCAAGAGTATCCGGATGAAATTATAGGAGCTAATAATATTTCGTTAAAA CAAGCAAAAATAAATTATGCGAAATTCTGCGCAGTAGAGGAAAAATATAT TACACTTGTTCGAAAACCGAGACAGGATGAACTACTGGAGTGA ORF73 (SEQ ID NO:157) AAGAAGGAAAGAAGCATGGAATATGAACAAATGGCTGATAGTTTAGCATA TGGTGAGGAATATAATTTTTACTACAAAAATGAGGAATATTGGTTAAGTA AAAATCGGGAAGGACATTACTTAACGAAAGTATCCGATGGAGAAACACAA GAATTTAGGACTTCAGAAGACTTATTAGGAACAGCTAGAATAAATGGAAA ACTTATAATAGAAATTTGGGAAAATATACAAAGTCAATTCTAA ORF74 (SEQ ID NO:158) AAAATAAATGAGGTGAAACAATTGAAAAAATTAACAACAGAACAGTCTTT TGAATATTACCTTTCTTCGCTATGTATGTTAGGATTGCATACAATTAATT TATCCGACGAAGAAATTGAATATGAAATATTTGAAGAGTTAGCAATTGAT TATCCAGCTGCTTTGAGTCCATATACTAGGGAATTGTTGGTGGATAATGA CATAATTGATAGAGAGCTTTCTTTACTAAGCAAGCAGCTGCAAACTAAAC TTTTTGAACTTGATGGAGGAATTCTGTGGTAA ORF757 (SEQ ID NO:159) GGAGTGTTAATTATGAAAAATACAGTTCATGATAGCGAAATATTGTCTTA TCATGCAGATTTTGAGAATTCTCAATTAATCATGTTTGTTAAGGATGAAG AAAACAGAAAATATAAAGTCATATTTGAGGGGCTTTTAACTTTCTGCTTT GAACACCAAATGTCTAATAGTATCATTTTAGACATAGTAAAAGGAGAGGT TAGCAGCTTTATAAGTGAGAAGTCAATTTTACTTTCTGAAGGCAAAAACT ATTTTTGGCCACTAGATTATGAAAGTGAGGACGAACTACTAAATTATTTA AACGAGAAAAAATTAAATTATTATGAGTTACAAGCTTCATATGGGTTAAA CGGTTGGATATTATGTTCTCACTATCATATTGAATTATAG ORF799 (SEQ ID NO:160) ATGAGACAACCTTTTCAAGTTTTAGTTATACCGTTTATTAAAACGGAAGC AAATTATCAGTTTGGTGTTTTACATAGAACGGATGCAGATGTTTGGCAGT TTGTAGCTGGTGGAGGAGAAGATGAAGAGGCTATTTCAGAGACTGCTAAA CGTGAAAGTATAGAAGAGTTGAATTTGGATGTCGATGTTAAAATGTATAG CTTGGATTCACATGCATCCATCCCTAATTTTCATTTCTCATTTAACAAAC CATATGTTGTTCCAGAATATTGTTTTGCCATTGATTTAACGAGTTGTTCA TATCAGGTTACATTATCTTTAGAGCATAGCGAGTTGCGCTGGGTTTCTTA CGAGTCTGCTGTTCAGTTATTGGAGTGGGATAGTAATAAAACGGCGCTTT ATGAGCTAAATGAACGGTTGAAAAACAATGATATGAAGGCAATGTAA ORF817 (SEQ ID NO:161) AAAAGAGGGAGCATAATGAAAAAAAGGTTAATAGGTATTATTACAGCATT ATTGTTAGTAAGTGGGATTTTGCTATCTCCGCAGATGGCTCAGGCGGAAA CAAAAGTGGATTATGACGCATTGTATCAACAGGGAGTATCTGAAGGGATT ATTAATAAAGCAGATGTAAGCTTAGAAACATGGATAAAAGAGAATGAAAG TGAGTATAATCAAGTCTATCAAGATGGTTTAAAAGATGGTGTCTATGATG CATCATTGTCGTATGAAGAATGGATAAAGTTAAACAACTATGGACAACCT CCTGTAGTAGATGAAAATTGGGAAGAAGTTCCACAGAAGCCAATGCTTAA AGGTGTGTATAAAGGTTATAATATTAAAAAAGGGGACATTCTGATTACAA ATGGAACATCTTCTTCCGGATTATTGGGACATGCTGCTATTGCGAATGGG AATGAGTATATATTAGATATTCCTGGGGCTGGAAAAACGACAAGGCAAGT ACCTACAAGTAAATGGATGAGTGATTATGATCCAGAAGGATGGGTAAAAG TTTATCGCCTGAAGGATAGTTCTGTTGCTAATGCCGCAGCCAATTGGGCG GACAAAAACTATTATTCCACCAAAGGCACATCCAAACAAAATATTTTCCC AAAATACGGTATGACAGGAAGTCGATATAGTAAGAACCCTACTTATTGTT CTAAAATTGTACTTCAAGCCTATTATTTCGGAACAGGAAATAAGCCTGTT GTGCAAGTATTTCCGTCCTTAGTTACTGTGTATGATTTACCAAACTATTT TTCAAAAGCATATAAGCCACAACAAGTGAAATACTTTAAATAA ORF819 (SEQ ID NO:162) AAAATGATTGGAATGTTCCACTATTTACTTCCCTTAAACCAAATTCCCCA CAACTTTCATGCGCAACCTGGGCGCATTAGCCAGATGATGCACCAATGGG ATTTCTTCCACTACTTCAACCGAGTCAGTCACTGTACCGGCCAAGGTTAC TTATTCTCTCGCTTTTGCTCGCCATTTTGCAGCGCTTCATCCCGCTTGAT TTGGGAAATAGATTCGCCGATTGCGTTGGCAACTAGGTCGATTTTATCGC GGAAAATTTGTGCAACAACAGAGGTTTCGTCTGGAATAATTACACTACCG AACTGTTTTTCATTTTATCAATCGCATCTTCGGTCATTTCAGTAA ORF949 (SEQ ID NO:163) ACTTTGAAAAAATTAGTAAAATCGGCGGTTGTTTTTGCAAGCCTTGTTTT TATTGGCACCTCCGCTACTATGATTACAGAAAAAGCAAGTGCTGCTTCCA TTGATCCGGTGCAAAAAGCAGATGGTCAAGCTACTTATATCCCCAAAGGA GTTAGAGATGGGACTGCAACGGAAGAACATGACGGCTTTGAAGATGGAAC TAATAGCGTACTACAGCAAGTCCCTTTGCTTCGCGCAACAACAGGATACC CTGATGTTAATGCCTATATTAAATCAAACAAATTTTCAACAGCAAAAATA GAAAAACAATTAAAAAGCCAATTTCCTAAATTCAACTATCGTAATGGTTA CGGCAAACCAGAAGGAATAGTTATTCATGAAACAGCAAATAATTCATCTA CTATTACAGGTGAAATCAATTATATGAGTACCAACTACAACAATGCCTTT GTTCACGCTTTTGTAGACAAGTCTCGTATAATCCAAATCCATCCTACTGA AAATGGTGTTTGGGGAGCAGGACAATATGCTAATGCTCGTTTTATCCAAG TTGAATTAGTTCGTTCGAAGACATTCGATGAATTTGCTCGTTCTATTAAT AACTATGCCTATTATGCTGCGTACCTTTTAGATCAATATAACCTTCCTGT TGATAGCGCGCACAGTGACGGCAAAGGAACAGTCTGGTCCCACGATGCAG TTACACGTTATTTAGGCGGAACAACCCATACTGATCCTGTTTCTTATTTC AACCAATGGGGTTATAATTTCAATAGTTTTGTTACATTGATTAATGAAAA GTACAAAGCGATTCAAGCTAGCAAAGTTACTTACGACAAAATCGAATACG ATAAAGGCGTCACAGCCTACGCTAGAGTTAAAACTGCACCTGGTAATGCA GTTTGGACAAAACCTTACAGAACAGAAGGCTCTAAACTTGTTAATCAACT TTCTGTCTACCAAGGTAAAAACATGCGGATCTTGCGTGAAGCTAAAACAC CAATTACTACTTGGTATCAATTCAGCATTGACGGGAAAGTAATCGGTTGG GTTGATACTCGTGCACTCGATACGTTCTACAAACAAAGCATGGAACAACC AGCTAATTTAACTCGCTATGTCGCTTCCAACAAAACTGGTGAGGCCTACT ACAAAGTACCTGTTGTTGATGCGGATGTCAAATGGGGCACTTTAGCTGCT TATAAAGATCAAAAACTAACCGTGGATAAACAAGCAACGGTGGAAGGGCA ACTTTGGTATCGCGTTAGAACAAGCACTACCTTTATTGGTTGGACGAAAG CTTCCAACTTAACAGCTACCTCTCCATTTGATAAGATTGAATACGATAAA GGTGTCACAGCCTATGCTAGAGTTAAAACTGCACCTGGTAATGCCGTTTG GACAAAACCTTACAGAACGGAAGGCTCTAAACTTGTCAATCAACTTTCGG TCTACCAAGGCAAAAACATGCGGATCTTGCGCGAAGCTAAAACAGTAATT ACTACCTGGTATCAATTTAGTATTGATGGGAAAGTAATCGGTTGGGTTGA TACTCGTGCACTCGATACGTTCTATAAGCAAAGCATGGAGAAAGATACTA ATTTAACTCGCTATGTGATTGCGAACAAAGTAAACGAAGCGTACTACAAA GTGCCTGTTGTGGATGCGGATGTTAGATGGGGCACTTTAGCTGCTTATAA AGATCAAAAACTAACCGTGGATAAACAAGCAACGGTCGAAGGACAGCTTT GGTACCGCGTTAGAACAAGCACTACTTTTATCGGTTGGACAAAAGCTTCG AACTTAACAACAACTACGCCATACGATAAAATTGAATATGATAAAGGCGC CACAGCCTATGCTAGAGTAAAAACTGCGCCAGGCAATGCCGTTTGGACAA AACCTTACAGAACGGAAGGCTCTAAACTTGTTAATCAACTTTCGGTCTAC CAAGGTAAAAACATGCGAATCTTGCGCGAAGCTAAAACAGTAATTACTAC CTGGTATCAATTCAGCATTGACGGGAAAGTAATCGGTTGGGTTGATACTC GTGCACTCGATACGTTCTATAAGCAAAGCATGGAGAAAGATACTAATTTA ACTCGCTATGTGATTGCGAACAAAGTAAACGAAGCGTACTACAAAGTTCC TGTTGTAGATGCGGATGTTAGATGGGGCACTTTAGCTGCTTACAAAGGTC AAAAACTAACCGTGGATAAACAAGCAACGGTCGAAGGGCAACTTTGGTAT CGAATAAGAACAAGCTCCACCTTTATTGGTTGGACAAAAGCTTCGAACCT TAGTGCTACTAAATAA

TABLE 4 ORF1025 (SEQ ID NO:164) VALVMKINKIIEYIVVAIIVLGWTYFIVIKEILPKNIGFISLVILSIILY FVGKRLNGKHSR ORF104 (SEQ ID NO:165) MKKILGGILIIFVIGLFAWRVYDVKANSFSYENKAHAEQEKFQLGSSTIS AGKAFVVSDADLNKYVTKDYFKQENKTLLLVQLESTEKDIRISDFQLGYK EFVTLSDTSAASYEFEDGVYKMVLGFNIPKELLATNKTFTLVTPSKYWKN GARDVVEISL ORF105 (SEQ ID NO:166) MNYIKVNHLTKVINNNTVLDDINFELKQGGIYSFIGHNGSGKTMLFRALC GFIAPTSGEVTINGISISKTRSFPEKTGIIIETPGFLANYTGYKNLEYLA SIRNQIGEKEILAALEQVGLSGKENLKVKKYSLGMRQRLGIAQAIMEDPD LLIFDEPTNSLDKAGSQSFIDLILDLKEKGKTILLASHHIADIDGISDEI FEMEAGQIINRRKV ORF1063 (SEQ ID NO:167) MKNLFRLFLVFSIVIIGVVSFQAIDASANETDVYPLPARIIDVFPDENLA EDMVENFGKKDVTDVITQDDVDAVTSLGLGYFTNYLTDEDLQMLGNAYFT NVNNIMIYPTQTMFTGFPDLPTLPKLDTLRAEGNLSSEVLPENITVPDYQ NYPELKYLDLSNRTIVGGLPNFSNIPKLETLLMSSCGLASEDAPDFTNLK NLQKVNFQTNQFRTEMTDFTHLDSLVSMDLSYNYLNVLPP ORF1227 (SEQ ID NO:168) VNITKNGLYIIIGANGVGKTTLAKKILQANRSISCMMKQDDNQILEYETV LTNISMNEIAEKTVINFLEEHQLDYLITKKSKFLSGGEKRLVNLLRAILS NQEVLILDEPSNDLDIDVFEKAKQIIYQAAKSKIILLITHDDRFTEYDKK IEIMKNQSYEADSFSFNKESSKARIIKIKPRRTYFLYIFYLICMMIFAIF LVILLKTNAEETSPSNEKGTYGLATIYSTNASSYDNNEAINTMLIQSATK FNKAKFFTEETRINEDEYYEEAINLKKDTYQELIYLELYDPKTEEFINIK AVMMEALRGDLKLNAETEFISNDENYYKNSDSPSFHVPKSLTLTEIKKAK IKQLGFELHYSNTLQSNQVEIEFNPSVYAQILKKVNQQDVLITEAYVQLK AQESFYDFLAENKLYAKKIFIKGYEPELLNAEVNQYSNAVMLIKKVALLI CLLLLVLLILLIMYEVSYKNSYSTLTYYGYNEKELLQFRKKTYLITNFKI FSVISTVIFLLIMWSIVHSVLITAIIGVVMIFFFFAYIVIPLIIKNNIRK AII ORF1228 (SEQ ID NO:169) MNKINKFSIFSITKPGIYTITGSNGSGKTTFIENELKNNTNKVKDVAYFA QKNWKYKTNVEKYLHFPKTNPSLVQKYCELFSVDNYYLEKDIQLLSGGEF VKVELVRTLALDSSIIILDEPTNNLDNKSSEILANILSELAKTKIIYLVS HDTRLEHFFDKTIFVDKDRIEVSSNVEIEQNEIQVNSKRVVSNGRILKYL LSSKFNFLMFAFIIVLTILLTNITSTIILRSVPIEENLTSDYNFELMDIA ENYSRYFNIEMTESEIEAEFQEPNHLTTNELIELQDKDYIKQIYVVDESY INEFVLDNSKFEVLALPEIITDSPNYVNAFPVTKMHLTKGRFPKDDAKEI ALSFAQLKKFFHDDISEESAIGNKLEFEDELYEIVGIVNSPVAAISYSKQ VSKGTVEVEDKTSEKLNNILLKLEKENYDNPNFSIISIKLASKNQHELLN YLKVHGPSYQYASNYVDSISQVAFYKQNLAKILLISVIFSLIVSVLIFIF GRKSFSLINGFLNDMSNLNFTPRKNKRFIYVIMILDFLLSMPACLLVSRV IIGDNIGMLMILPTLGGSAIIFMLTLLLMSYRDKKNDFRNL ORF1272 (SEQ ID NO:170) SRHVINCNFRNLFYFIKSNKTSNKVSEFQYLLYIFCFQWLILLLIRFFYF SLFYFFQNKVSFTHQTITKAYVLLFVLWIAVFIVCCFRFRKKLRKGDFRK DSVLQNKRGNLGLNLSKKTYISIGAFFAFILLAQLIGGVMIYVFFISIAV LCMALSFLGLVIFPEQIFTAYCNFKEFHIEE ORF1384 (SEQ ID NO:171) VEPDFAYQFETREEMVEKSSWYAEDFDIVASLEEKYLAGFYQNQVYGYVT PVEFQEEEMKRAIPSEMFVPLKGLEVSELADWADGFPPELQERYNELAES VEE ORF1385 (SEQ ID NO:172) MSITEEEFEEEQVSELFINYLEKCTPEEIHQVVVEWNFDNPKKPIHWIAN STKTDKGTALMLWSRTLLINLKREKRWLKKAVGMRKKILILLLVWKKST ORF1386 (SEQ ID NO:173) MNEFPVVYEPEYMTIYLLVIIGVFSTTLALSLEKYKFTLAGKALIGMCFI SLAVLFIYVLELAYLSDIADLLFHTIGVWEVVLFTHPYIFLILAILLGGE KKPPHVPKLKK ORF1387 (SEQ ID NO:174) MLSDITITIPNKTAQTKYDNLAKNMSFKSKEDLESLLDLIKILYINNYYE EALLCCRLTNDVEFDNDFDVWTFIHRIWMFEMQILVHFGEKEEAEEIATK IEAHFKIPMKIWNTPEKRYAQYKKNRSRIVLKDLSYEEKINSTPRGESGT FDWKFVALSSLIKPITLNNMTGVSVEEAEEIFRQYSAELQQTKKYGVSL ORF1388 (SEQ ID NO:175) LLYSFQKFDWLIGYSDDGDYVTCVDNGLFFSIDKMVLLDNDINVHLLPVQ AH ORF1389 (SEQ ID NO:176) MKILYYGSPIGEGDCYIVSKNLIGLLVILMMAIMLLA ORF1390 (SEQ ID NO:177) LRLTRLKITDLHSSYSYDIEFNKDITFFYGTNGSGKTTILNILSSIVTGK IYQLFTYEFSSITLHYCFERTKNKEQKIEILTPPPLCIEVTFNGQRYILE KFNESLSNYRQSINRNLEKDFFGENKFLKEIADMFNYVYLPLNRHISLDN NMLYDNRLHRERTINAMMHGVEEDENDYYMERDKSMKKVQYLIKTKVMRN NTRINRLNDNFRNQILRSSIDIHKLTFSIEEIFNEVKNLKVEEIKDIKTS YINILKNLNQITQIEEKNYVNFFDNYIREIKENENIEDNSVSIQLILKYN EIAKIKNIVKLAEDMETKKAKVVESVNLFCETINSFISTDGTEKKEILID ENGGIYLQNVIEKKQLSIYKLSSGEKQIVIFYANLIFGVNENKRGIFIVD EPELSLHLSWQKLFIEKTIELNKNIQFIFATHSPEIIGKYYNKTFELKKK IDR ORF1391 (SEQ ID NO:178) MNQLQYSEDALKNRYLFFKEINEINIFVEDKGKEYEYEEILSKVFADEYH IQTIYALGGKPQVLSAFRDCKEHVSSNNNIKNIYLLDGDFDQYLDNIVME SHPHIIYLQSYNIENYFLNEESVVTFMQGKMKMLKNDVRTKIAYSEWLSN TLYNIENIFILYCIIQEKELGIPNVGDSEYKVINMIDGSINMTRYEDLKK QISNCTVNIDLVEQEMKAKIHNINPNVFDLICGKHLICSLYRHLLKITKG FSYDEFRWHLVQNVEVSRLNFIKERVANL ORF1400 (SEQ ID NO:179) MNSDSNNNINKNREAGISIIIPLYNVEEVILETLESIHEQTFDMYEVLLI DDGSTDKTIEMVTEYISDKPKFQLHTQPNGGPASARNYGLRLANRMYICF VDSDDIIPNYALQLMYDGAISTGSKLITGATKRFNSEGEWFIPMHIQYNI AKPGMKTLLKNPELFYSIGPCAKLYHHSLIDGVFFPENIRYGEDQPFVLH ALLQAENIYTVEKVVYYYRLRDGESQSLTQSVNKDPIRILKSVFQIFDYG EAELLKNNTEYEIALKYYQRVSSVELWGALRAAIESKKSENQQIAFTMTL DWLKTKSDDFLNIIPSFRYFLLFSSIERVRYITRDNKENYRQLITYLWER QGEEAKIAFRKAYPIHMKAALQIMEHNNWGAARKISFKFIIRRKFKAPIL IRKISRGIIFRLATLMPRKKDQVILATERSTSLEGNLLAIYDYLFYNDMP QKVYVFLRKNRNWFEMFQLYYALGRTKTIVLDDYYNKIYGLKFNKKTHVV QSWHATGAFKKFGFSALEGTDANTEEFETRAHSPYTDVLVSSEGIIPEYM EAFRKQANQIKPIGVPRTDVFFDQEYVAYTKEKYMKMYPQLRDKKVLLYA PTFRGGPNERFNYSVVLDIAALKKELGDTHILILKFHPVIKNVSFNVDEN DPFILDLTLNNDINDLMLFSDALITDYSSVIFEFSLMNKPIYFFAYDIDD YLDERGFYFDYKATIPGEVFKDTPSLIESIKTGKYNYDELEVFKKKFVGS LDGNSTKRFVETYIVQANEEVKDL ORF1445 (SEQ ID NO:180) MKKRIQHLDFYFVGIIVIAIFFNFYGIWNDDTVNPYYTAAVTSMVQNIHN FFYGAFDPAGFITVDKPPVALWLQAISALIFGIHGWSVILPQALAGVGSV ILLYVLVKPRFGAWAARITALIMALTPIAVAVTRTNNMDAILVFVLLLAT FFLFKAVHRAKIGWLLLSFALIGVGFNVKMLQAFMVVPAFLLFYFIATKL SWRKKLVQLVIALVLMLGVSVSWAVVVDQTAASERTYIGSSQTNSVLELA FGYNGMERLLGQETGTGSNGNVEMGTPPSTNSTDSSNATPPTPPSGSMQD GANGGTPPQGNNGTPPTGAPSNAANGGGNGSKMTGSTGMFGTGNAGPLRL FQTALGDQISWFLPLAIIGMLAIFLVYRNENKRIYQLTSRQKEIVFWAAW LIPVAGFFSIAGFFHHYYLIMLAPPIALLSGVGLVALFRLYQDKENWQRF LLPAAVTLTGGLQAFFVAAYLPVLAVVIGIAALITSIILIVLRPQPSKLT AKITALALAILLIAPTYWSLTPILYGGNSSLPEAGPQLKQSSGGGFADAS VDSDLISYLQKNNTGETYLFGTTDATTAGPYIIKTKEAVMALGGFNGTDP TLTVKQLIQMIQAGEIKYFYLPSNSKASDSDVVKWIQENGTEIDSSKWSS SGSTDDDTTSSASFNMQGGAQGMNGTGTGTLYQL KORF149 (SEQ ID NO:181) AFKFYEMPSTDIAYSRTGKITNTSGHAVWTQPCGQINSTLKGPASDYLNK EITIWRKVENKRGTYYQFSETKTPNIKAWLDARAITLYDQVHFNEEYNQM AVISTVIGHAVWSTPYLQSDSKLIAPASNYEGKRVEIIRRAKTTRSIYYQ FSYDNKVIGWLDTRAFSLIPSNTAMVISNSTNDIFSNITDAYNKKTL ORF1490 (SEQ ID NO:182) MTKEAEIGKQIFIHVGGMENVSRIAHCMTRVRLGIVDSDLVDVAGLKKVP GVIGVVEDDTLQIIVGPGVVNKVAGAMAEMAGVKIGETIQENLDSGTKTG KELVEEKASKTKAELKAKQNNSSGFKRLLKSISNIFVPLIPGFVGAGLIA GIAAIISNNITAGNLDAAVWTQYIDILGVINKGIFAFLAIYVGINTANEF GGTPVLGGGIAGITLLSGLAEGHTITNIFTGDPIVAGQGGIIGVLLAVWL MCVLEKNLRKIIPNAIDIIFTPTLVLLIIGLVTIFLIMPFAGLVSDGLVN GINWVIEVGGVFAGFVLGTLFLPMVMFGLHQVLTPIHVEMIAQNGYTILL PILAMAGGGQVGAAIALWIRCRKNKPLVNMIKGGLPVGILGIGEPLIYGV TIPLGKPFLTACLGGGIGGAVIGYFGNVGAIAIGPSGVALIPLIANNEWL SYVIGLIAAYLGGFILTYFFGTPKDAMNSVEL ORF1491 (SEQ ID NO:183) MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELI VSGVISCFQKGGRLIYLGAGTSGRLGVLDAAECVPTFGVSKEQVIGLIAG GEKAFVAAIEFAEDSKILGENDLKQILKTANDFVIGIAASGRTPYVIGAL DYAKSSVGAKTGAISCNANAKISAHADIAVEVVTGAEILTGSTRLKAGTA QKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRIIMEATEADY ETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK ORF1492 (SEQ ID NO:184) MSNGSIINRIEGILNDLPKSEKKIGQAVLANPEFTTTASIHKIAQKADAS GAAVIRFCKSIGLQSFPELKRQLSLDLAQPQKKGYYDIEPNEDFHTITEK LVSNMIQTMNDTASQLDEAKVLEACELLGEADTIYTYGVGASWLVAEDIS QKWLRAGKHVLATQDAHVLAMAFATGKKKAVFIAISNSGETSEVLQLVDQ AKLNNVIVISLTRFGSNKLKEKADLSLETSRAPEAEIRSTATSSRQAQLL VIDILFYYYASHHYDEMIQQIKHSREATNRFRE ORF150 (SEQ ID NO:185) MLKRNVQKGMISLIAIMMFLSMFSFTNLNSIKTVEAATTAYNTIEYNKSV NLDANIAYPETNAFWSAPYYSEGSTFISSATAPSYAKKDVKLIREAKTER GIYYQVKLGDKIIGWLDK ORF1504 (SEQ ID NO:186) MQKAIKIMLVLFLMTTVFLPFSNVRAASTDVVNIPDPYLNEGLKSIVGNP FLTELTEANLETISVADISYMNGVPGYAVTGLISDLTGLEKAVNMTKLYF SNQTEIKNLNQIKDLPNLKKIVGVTTGLNDIKALGEMPALEELELGGDYI TDFTPLLEKDNLKSFSYNSYAWLNPAYHQIDNEEFKKFTNLKSLESLDVT WNNITDLSSLTANDHITNLNLSYNKFTNIAPIATMKELKVLYLNNNNLTS IDSLNTLRGLTIAYADNNNITDLSNLKDFFEGMDVVGDYKGLQVNNQTIT LPTINIKEGGTAISNNPTLDIDGEKMPVSSISDGGTVSTDNKTVSFTNLP VGNKTVTYKATFTATSTKGVPLSYSIKVSQPINVSAQSDSTVNVFYKDEN GDELAPSETISGKSGENYQTIEKTITNYTLKEIEGQPsGQFGDSDATVTY VYEKADGAPVTVKYVDVDGNELATSDTLNGKIDAPYQSTAKSITGWTVKT TPANATGVFTNANQTVTYVYEKADGAPVTVKYVDADGNELATSDTLNGKI DAPYQTTAKSLSGWAVKTTPTNATGVFTNANQTVTYVYEKADGAPVTVKY VDVDGNELATSDTLNGKIDAPYQSTAKSITGWTVKTTPANATGVFTNANQ TVTYVYEKADGAPVTVKYVDADGNELATSDTLNGKIDAPYQSTAKSITGW AVKTTPANATGVFTNANQTVTYVYEKADGAPVTVKYVDVDGNELATPDTL NGKLDTSYAATAKNLSGWKLTATPANANGVFTTDAQTVTFVYAKQEDNPK KEDKNKTPIKISENKPTASKVTRIKKQTKLPKTGDNQQDSILFGLIGTCF VLLGIYSISKKNS ORF1590 (SEQ ID NO:187) MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDE NLANAIKATLNKPSTTSDVSQAELDSISEVTAESSNIASLEGAQYLNNID TLILNNNKITDLNSLAGLSKLRILEANDNQLSDISALANVTSLHQLRIAG NQIKQLNGVSNLINLETIELSNNQITDISPVSGLKNLIGLGIDYNDISDL SPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQISDVTPIANL ANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELV VPNNIKDEMGALISPDTISDNGVYASPNIKWNLANYTNQVSYTFNKQLAQ GSFSGTVTQPLHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFT GWYDAKTGGNKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKV TYQSLLEEPAAPTKDGYTFKGWYDAKTGGTKWDFATGKMPAGNITLYAQF TKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGDENTMLPIFVG VFLLGTATLILRKTIKVK ORF1654 (SEQ ID NO:188) MKKQIITIAGGGSTYTPGIIQAVLNGQERLPVSEIRLYDIEATRNENMYL ILDYMLEQQGFSSIKLVQTTNPEEAFTGADFIFSQIRVGGLKMRDKDEKI PLKHGLVGQETCGLGGFSYGLRSIGPLLELVGFIQKYAPEAWILNYTNPE TIISEAVRRQFPGIRMINVCDMTIGIEDTLAKNYGYDRDNWIATYYGLNH FGWYTKIYDKSLKRDIMPELLEKLKVQEIKEEDPSWNRAFNNIRFNVQNF PDNLPNNYLEYYLYPDMYVDYADPNYTRANTVMDGREQKTQEMADKIRNK EKGDVLDFYFGVHGLYIVDIATSLLNDEKSRFMLIVENKGSIPNLRSDAV VEVPAYVGATGVEAIALPAIGDFHKGMIVIEAQVAAEKLLVDAYFEKSYQ KALQAFTLNQSVPNATVAKKVLDEMMIENKAFWPELK ORF1655 (SEQ ID NO:189) MLNQRQKNILSTLYNENNWLLGKKLADLFQISDRTIRNDIRVIKESIGDD FIFTSKKLGYAYNMEKPFPIDVEAETGFEQNRMAQLIQQLLVEEGVDIYE YGAETFTSESTIQRDIQWLRGYFEQLLGLDVVIHSSDGVYAISASPTTKM ELLNRIATLDEGLKTNLLTNCFPEINHEKIRQILLEMIHQHKIVLKYFDE TILLAQLIYGSAFFQKHAEQQTSTKIANPFLKQLFDTIQQEMGYQISAEM KQFIVSEYEKIVANNHFENQVTTKMVLEGELYQEILLILEEIKHVYLIDF TADLDVTSDMTKHIFIALERAKRGIVIKNQVTHIITQQYSYLLDIAIFIG EKLLERLGVILNQEEIILLVMYLYQYYRKIEAKHQLNQVVRIALIVLEGK AANYYLREQLAEVLRPVNAEVIEITDNSQCQLLLAENIDVDLCISTKKID LPAEVPCIILANNIGLIEEVTIKKQLSATVEANKMKKFAYIKEKYLHEEL FLTDYAYEQKYNAIEFLSQYCIDKEYVPERFTEKLYNREQLFSTAIPTGI AIPHPIKNVARKSGIFICILKKPCAWDTHKVSLIMIPMIEELDGTEAPLI NDFLSLIASNKSYVEQISACSTYRECVELLQTIYNNNE ORF1680 (SEQ ID NO:190) MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAIS KNVSTQLGDMGSNLLTVNFYSDNPNDKFTYKDAKKLLNEDEIGSPEVMQT KEVRTSEKTASNQVAGINEYYASIKNLELASGRFCSNVDVIYAQKVTIIG SEIAKTYFKEQNPIGEYLQIAGARYMVIGVLKEKGESLFGSADKKLFIPI SSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFFPNNEDAYTVV NQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREI GIRKAIGASSGNILMQFLIEAVVLSLVGGCIGILLGIFSAQIVTTTSSFE MYVSASTILLAVGFSMCIGIVFGVIPAQKASKKKPIDALRAD ORF1681 (SEQ ID NO:191) LIQLFNISKSYQMGECTIKALDNVSLQIDQGEFLAIIGPSGSGKSTLMNI LGILDRATIGEYYLNKTNLMRISDKKISRIRNRKIGFIFQQFNLMPRLTA FENVELPLVYRGVGKATRKKVVLKSLERVGLLDKEKHIPAQLSGGQQQRI AIARAIAGSPELILADEPTGALDSKTGEEVMTLLREIHREGNTLIMITHD KEIANQAERIIEIKDGKLREWNKL ORF1683 (SEQ ID NO:192) LKKISWVIIMLVIVAASVGYYFIKENERKTPQTIDYKTVETKRTDLSVYV SAEGHIVKKVNEWPDYEDFAVKIMVDELEINQIKEKQTADVYVEAVNNKV YKGKVVDINEKGIINGSVTSYAVTIDLEDETKVKENMSVSADVLVALEKK ILTIPIEAVNTDKADKHYVYTVDANKQKKKIWIEVGKHNTKSIQVVKGLT EKQLVIIP ORF1684 (SEQ ID NO:193) MPKIAKGNRLENVAFEYIKNKITTGEYPTGYRVVEAKLSQELNMSRTPIR RAIINLCHSGFLVHQYNRGAFVQNTEVTITEFFSRMKLVELLMYESTEKL ILREDYIVVDDIIEIAEKVIQYEKNKEYELMRDTFEDFIVAFIGKLNNDY FNRIIQELWNGINDNATKEVRLIIVSASDRIAEELANIIEILKSWNYGEL KKCFQHIMNAMILIAF ORF1717 (SEQ ID NO:194) MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLI AEEVAQDKPAEVENLEEIPTTDELMQNPDVREQSVADSDDPDLTAVSSGD YWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDF SSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDN YYPETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKEL DVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKK LDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNL EELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECS SLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTT SLTYLFVSRNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGY RKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWY LDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGI NRGSKALSVGLNPLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPE KAILTIAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE ORF1718 (SEQ ID NO:195) MHSKEVFLMREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPT LISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIR ESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLY ISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDLLESC PKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEE SKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSF FYMDEQLEEMGFMKLVDFASERVNDNLSIPFSEKEMELLRYSFASINYRY FLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLK PFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSS YYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYV KINDNLAKIARKNLSLIKKIRETLVGMDMENV ORF1739 (SEQ ID NO:196) MKFAIIMPFYNAEKRLALSIDSIIKQSYSFLKHVEVLLINDGSTDGSGAI ANRYATKYPNNIRVLTVPNGGPAKARNIGIHNVSEDTDFVGFLDADDIMS ENNLASIVTFLNESNVSMLVPAFYYLDDFGSKKKISPHKLNYRFANGNRV ADIEKEPEAIHFYIGGTFLRYDCLKEFTFDESLYFAEDQLLITQFLLKYR SYGLIADAGYYYYRDLKQKGSLVSSSWKKPERYTPFLQKVYQTYLTDSKE IYGKVIPYVKYLIAYHAKLFFYKENTYFREVLSESEQAIFVQELQKILQE VGASTIMELDTPLVVKEMMCSILQNGWPLQFETAEKQDIPLVTVKENYRI GKTVAIELLLEEADIHDVKWVARTSFKEMPARLVKRKENQTIWDVVVREK GTVEKAVFKLKPYQTKARLFYQDEEKDTPIADINIISSILGKLKRNRALK RKFKQGGVS ORF1813 (SEQ ID NO:197) MWVLMKNGIVDVEATNAYNAAVLNGELPHESNEAQEEAELLQAVIQSVKE GIDPVTGQEISKAQGFSIISGFIFYYTSGGYKGKKLKIPKKLLNNIKNRR SKAPKLSTLSEKEQLKLANKYKKKAPIAIPDNAKIKAQTKKAGYEQITYK WNDGQFKYEVRWHTRTPEAPLEQGNTNVVQRTVPGNGGDKPQTFFKIGDD EWVEGYKWYDAINARKAGNATPEQIKILDKGHWKE ORF1849 (SEQ ID NO:198) MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALAT EIQTTLGKSSTAEVVTQTDLDTINSLTLTSKGISSLEGMNYLTNLGTLIL TGNQVSDISPLKGLTNLTMLQLSGNPISDISALSNLKNLQALDINDAQVT DITPLSGLTNLKGLGLYNNQLENLSGVNSLHQLRSLNVSNNKLTNLDELQ ALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDTTPLAGLTKVQ TLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTN QLIVNEPISFESTVTIPNLIKNIAEQTIDPDTISDNGVYANEAVTWNLPT YIPKVSYTFIERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVE TGTLLQEPPTPVKEGYTFNGWYDAETGGTKWDFTADTMPANDITLYAQFS INSYTATFDVDGVISTQAVEYQGLLEEPPAPTKDGYTFKGWYDAKTGGTK WDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSENSTEGAPNTS DIDTINHIVLPATGDDHVLFPIFIGTFLTSLALLTLRRK ORF1912 (SEQ ID NO:199) MSRIDIAELNGFLQGLRSSNAEAKKMIRGIQQAASKYAQDKSLKGQAVSA SQSYFASSYPSIAQSILEALEESEERLAQYIREFGSQVDSSPSARIDAEI LQEAMAKVASLKRKEEDLHRQLTAPNTKPDMQQVYVVQARSAHTQLLQAI EKEDILERYIAFEQSHAQFFSALTELIHSTGRAVQELKQNVTFHEKTGTY AVPKSVHASISLMRKAMDKARKENAKDSFPEAFEDYQLFAYTYVNDKGET VTMWLLERNGKRASNKELQAFLEENGAELDPILYTNLSGDELERKVNDAW KDGVNYLNGQKVTGFSEATLRSSAYVASVKDAMDDAGLTDMALGLGFGIA AARNKKIIAKKSEKVEVDLGRYSVATLNRDQARLVVEHLLERGEISLKDL GDIIPKGTPNTFKTTDTLKNGAKYEFQLADGQKAIIRWHEPDPIAAAKFP GSASGSRWTAQIKIGSKQVTINKGWTKKQNSNEVHIPIKGR ORF1913 (SEQ ID NO:200) MDSTHTRLEQQLQQVKKAQDVLQDNLGQTKRKQVEQEWLEEDSHQLEMEK QGLLDFLRGGWQGEEANGFHRYLEEQQHEEAMAWRKDLSEKRVHLEEEAR TTRAENHDIETKQASLRKEWNQ ORF1998 (SEQ ID NO:201) MKKLEKSVPVIRFKGFSEAWEQRKLGEIANSFEYGLNASSKTYDGENKYI RITDIDESSHVFNQDNLTSPDISLDNLNHYLLEEGDILLARTGASTGKSY CYNKIDGKVFFAGFLIRAKIKHEYNVSFIFQSTLTERYNNFIQVTSQRSG QPGINAQEYARFALYIPKLKEQQKIGDFFKQLDDTIALHQRKLDTLKQMK KGLLQQMFPKSEEDVPKIRFADFDEEWYQRKLGEISDKVIEKNKESTYFE TLTNSAEYGIISQREFFNKDISNEKNLNGYYIVRENDFVYNPRISNYAPV GPIKRNKLGRIGIVSPLYYVFRTFDTNQSFLEYYFDGTVWHNFMLLNGDS GARADRFAIKDSVLKEMPIPYSTLYEQEKISFFLDEITIIINLHQNKLKK LSSLKKAYLQNMFI ORF1999 (SEQ ID NO:202) MALSTEQKTKMWAMLNQTRGQIGLTAYKDYIFGILFYKYLSEKATHWLNG VLRGENWESVYSQDSVKALNYMKKNLGYAIQPNEFFVDWKKAIDTDRFNI GMMTDTFTHFNQQIAFEAKNDFEGIFDGMRFDSADLGANAQARASVMISM IELLSSPEFDLSGSNDTVSDIYEYLVAQFATVLASDMGQYYTPKEISNVM ARILTFGREDMEKFSIFDPTVGSGSLLLTTASYMKNSGRRGVIKYYGQEK DATPYRLSRNNLMMHGIEYNDININHADTLESDWPDGVVDGKDTPRNFDA VMANPPYSAHWNNKDREDDPRWREYGVSPKTKADYAFLLHCLYHLEDNGR MAIILPHGVLFRGASEGRIRKALIDKHQIEAIIGFPEKLFLNTPIPVCVV ILRKNRIESDVLFVDASKGFEKIKKQNNLRSEDVEKIVDTVINRKEIEKY SHVATLDEIKENDYNLNIPRYVDTFEEEEAIDLVALGNEMVALNADIKKA ETDFLGLLDELAVTADTKEIIEATKAVFR ORF2013 (SEQ ID NO:203) MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEE KTPQKPTLTNNLKQEKTVLQAGETYETVFPDAALATVIAKAATGSEDITQ EVSQTDLNKITSLTATSKGIVDLTGIDLLSKLTSLSISGNQITDISALNG LVNLSNLNVSNNKITSFNLNANSNLPMLSAVDIRSNNLKNINVQDQPKLR TIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFSSTPGLSKVIL ENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAV NTLYVSENLVTEIENLHAFPKLQTLTVDNNHISVLPTSLKTENPVLTTLS AMNQTITLKQKVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLF EDIKSVNAVDYQFSEPVQEATIQGTFSGKVTQPIKASKVPVISADAEMNY PKNETVSEAAFFKDISASVTDDATLTSDFESVVDFAKAGTYEVTLNAVNE DGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITEYLAAIHAKTN DGSPIESDFATAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAP VITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLDTAVTWGTVGG YTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITE FLAAIHAKTSDGSPIESDFATAVIWSTAGDYTVTLKSTNEDGVEAIPVEV KVHIVEPIAPTISNVTFDVDDVQTTESLEAGELISEPLSPTKEGYTFIGW YDSKTGGNKWDFTTDKNPAYNIILYAQFSKDTNKAEAAGGDKPSTPSSIK VSPTGQSESGNLENRSNIKLPATGDDNATVLLVGFGLLMLGLFIRLTQKK RAK ORF2017 (SEQ ID NO:204) MIKSLYIRRSLMMLITSLLVVSQLNLTVFQAFAEEKGEEPLSYEVQEELS KDKKKAKLKIKATSNNNQVEILSIETPDGNKIEGKEAEYTAEKNGDVNFI ISYKENIEGKETEIKTFKASYEVKNLIIEKEEANQSKDSVKQNETKAPLK NNQLKSGNDATVTLNIPAYDGTAWANGDIKDVNVTVDFSNSTSTSKEVEF TLPDGMRFVSIPVPSSFQVPTGVDSGVINRLSAGDPIGTAITSVTIPNKE TTYDKATFGTVNYKLTPGTEKVSFNFSVRVDANKYYGATDLKAPIKVEAF VGDNKMAIASEEKAIRAEGNKVVGYANQTHVSTMFRNWYKSFRTPDVLAS TDDEDSYAYTKSYSVVNGMNQVDERGTNIFSPKNVSTTLYYPEGMEYVGV VNEKYALLNENANTTITHYPEENKVVFDFKQQNFKGVTDTVYAIKYKIPK GTPAGTYTAPKVPHAVITTYDDKVFESDALTNNSTDLTTKTTLDACRVVD STENKMALIVGNKNINPDNETWAGNVRINNKDTAGTKTNQVFQIEFDSNW EASIVNIPFDGNRKDNDITNIQYKTNFDDTYQTYNGNLPKNSMKNIAILE ADAVGLQPGEYFTEVKANVGDFSTGYTSYSESGGFGEESTNSYGIVKPGI SSVQFKVSIWDEADEVNTKVSGTSVYSVADNITTAANGTANFYNEQGQVI KTAGAGDKFTTKATLVLFNYPYGTRTVLNDPEVYLRQLDGTKILPSSIKL TDQDGEEIEFSIKIETAKNGEKVYVLKTKDATVGRYVGYPSKHKFLNISY DTTIDVTLDKSLHTDIQQLLAWGGPNVKAATAANTFMDTGLDVNQNGIEN ERLLSANSSTLSVPKQDAVTVETFLNLAGEGAKASYVEGDDSTVSYFTPG TEADYTVRVTNTSTGIASAFELYIPIPKTGQNFGSKFQTETFKWDMKLND AVQLTDEQKAQFDISYATEANKNNYESESVYSAVPSDYGKVNNVRIKVKT KIDPGETQTIKVPLKVDETFNSATEGNKISERDVYNPYYRVTTNAYSGTL PGTKVGAELIILEASGFLFQDKDANGLYEKAQGDTALANETVELYKWNEN TSNYEPFLKNGEPVSVKTNADGKYTFNYNLNLSYGKYAVKFPERAGNQFT LKQVGQDNTINSTVSNKGTDKGWVKEIDPAQPVSQNINAGYMEYAPDNDL KVNLSAKIVQAGKSLKVTLPKVRATSGEAVEDTIEPSFFHNIQAITDGYK WTSNDTTLATTQTANDGSGIIVGISAGNKAIATTDIGITIKDIFDTEKKS TAPVYITEPSATIDQKEGLILGALNFSLEYKDSNKLTETEAITLAKTASF EEVKTGVLSTAQDCTSSVKVDAKQLKAIQEGSNQGGTYPLTYQVAKNGKT AEVVIQVKVEKDLTTVNVHDSILYLGDTWTATDNFDSALNKVGETVPFGD IQVEGSVDTNTAGIYSVTYTYKGVSKKAKIEVKENLTEINAHDSTIYTGD TWRAGDNFDSGLDKDGNALSLKDLTVIGTVNTNLAGVYTITYKYEDTVSS ITVTVKENKKGINGEDSSIYVGEAWTAADNFDNAVDKDGKPVSFADIKVK EEPKVDVNKAGRYQITYNYDGASTTVTLTVKEIKTAINAHDSILYIDDNW SAKDNFDSARDKDGNIVSFNDVQVLGTVDTSQAGTYPITYVYAGITKTIQ VIVKHPKTAVRAHDSVIYVGDNWKAQDNWDNTLDKAGQKVKWKDITVKEN PAVDVTKPGVYEVTYSYDGISATINVTVKPRKTTVKIHDSSFYAGNSWNA KDNFDHATNKAGEKVAFKDITVAGNVDSKTPGTYEISYVYDGVKAVAKVT VLKNHSILMVKDRVIKVGEKWNAKDSFIQATRRDGKNIPFSQVKVQGKVN LNKAGKYQVIYSVDPNEGTEDAGKQMLSVTATIQVENRGDAGLQDNEPRS VKDNNQRAANSNDIKLIPKTGDQTNQWVLWAGLCLTGLANLLWGFALRRR KVK ORF2019 (SEQ ID NO:205) MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLI AEEVAQEKPAEVENLEEIPTTDELMQNPEVLEKSVADSDDPDLTVVNSGA YWTLYYNSANGEYSLRNFGNVPSSIPSAWKSYLGNIKHIEIEEATLTGSF EAYFKSKIDGFRVLESVRIERSNLSGVTSFREAFFSAGIEKVIIRDNDYP TAPSLLTTESMFENCYNLTEFDVSGLDTSAVTNNKKMFYNCRTLEELDLS NLDTSSVNSMNSMFGYCESLEKLNVSNFDTSSVNDMYHMFRDCKALEKLD VSNFDTSSVTNMGGMFVNSTSLKELDVSNFDTSSVTNMSALFSSCRALEK LDVSNFDTSSVTTMLANFVACNSLEELDVSNFDTSSVTTMQSMFFECSSL EELDVSNFDTSSVTTMQSMFEKCTSLEELDLSTFDTSSVTNMQSMFINCA VLKSLYLDNFTTAKTMTDMFTGTTSLAYLFVSHNLQSFYGLANTNWYDEK NWVQFSNLSQLQTYHRNQSEPTGYRKGTFLSLTMDAMGGQFDDAEEQKVQ SKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWV ENYTVIIPASISLNEATELKVEGINRGSKTLSVGLNRTATSVSESNKLTL ANTADTTIQCLAPLSWDGSENNPKNAILTIAPGSEITEGDAVMAIEAPEN IQAGTYTGNLVFSINYE ORF2074 (SEQ ID NO:206) VEITETKEWWKESVVYQIYPRSFQDSNGDGIGDIRGIIERLPYLKDLGIN VIWLCPVYKSPMDDGGYDISDYYEIDPMFGTMSDMDELIEKAEKLGIKIL MDLVVNHTSDEHEWFEKAIADPKSKYRDYYIFREGVNGNPPNNWRSYFGG SAWEAVPGEENMFYLHAFSKKQPDLNWENIVVRNECIQMINWWLEKGLGG FRIDAILNLKKRIEYGTFRADGEDGLVFIGHWILNQPGIEEWLKEIDERT FKKHNAFTVAEADVPEERLSEFIGENGHFRMVFDFSYTDIDTPETGEWFK NSEWTVKELKEKIITNELVTQRNGWGAKYLENHDQPRSINKYLPQEYQDD RSKKMLGTLFMMLHGTPFIYQGQEIGMSNTRMESIDDYNDIATHDQYHRA ILSGMSPEEALEGMYRRSRDNSRTPMQWNNQKNAGFSDSDEIWLKANPNY LDINVEQEQIDDNSVLNFYKKLIHLRSDSSKYKEVAVYGELLPVESSDEV IAYKRKTDDAELLIIVNFSDSENQLCIEGTYEQVLANVALPEMVENVLEI PAYTGAVFSRVLEVD ORF2075 (SEQ ID NO:207) MKRATVWPNLLLIVLGCIWIFPIIWIVLTAFRAESGQFVSYIFPKEYTLD HFAYLFENHENFPFMLWVKNTMIVAVCSCLLSTFITVSMAYVLSRLRFRF KKTMLKTALVLNMFPAFMSMIAVYYILKAFGLTQSLTALVLIYSSTAALT FYIAKGFFDTIPKSLDESAMMDGATKLSIFTKITLPMSKPIIVYTALMAF MLPWMDFIFAKVIMGDNVPKYTVSIGLYSMLNQTTANTMYTTFAAGCILI AVPITILFIYLQKYYVEGITSGAVKG ORF2076 (SEQ ID NO:208) MMVKKNYFNIFKNGSVSTRLSYVIMGAGNLAHKQIAKGLLFLFSELAFLF FLVFYGITLIQGMATLGTVNQSWNFDKSLGIMVRTPGDNSMLMLIYGIMT VVICVLFLFLYLANIRSACQVEGFQRENKKIPTFKEDLKSLLDNKFHVTL LTIPMIGVVVFTIMPLVYMISLAFTNYDHEHLPPRNLFGWVGFVNFKNVL NGDISSTFFPVLGWTLIWALLATATCFFFGVLLALLINHKGVKFKKFWRT IFVITMAVPPFVSLLVMQNLLHAAGPLNTMLLNWGIIAEPIPFLTDALLA KVSVIFVNMWIGIPVTMLIATGILMNLPKDQLEAARMDGGNSFHLFRYIT FPQILTVMLPSLIQQFIGNINNFNVIYLLTGGGPSNSNFYGAGDTDLLVT WLYKLTVEAADYNLASVIGIVTFILSAAFSLFAYTRTNSYKEGSN ORF2110 (SEQ ID NO:209) MKKLRIFTLMLAFALFLLGGGIVAQAAEEAPIDEKIVGETVTNDGEEFIV DEISDLEDVNSTTGTLDTSDEVEVDLSGLTIENEEAVLTPGLKTIFGGDG RKLVTNTTQYPYSTSAYLVMEFPNGKTYIGSGQLIGEDSVLTAAHCLYGK KDGGWAKKVTVYPGYNGTKAPFGTAKARKMYVPKEWTKKEPSTEDYGVIK LDKNIGTKTGTMGLTTNTSGAITISGYHGDKKGKLYTQTGNISQVTANNV FYRLDTTGGSSGSGVYNSKKQILAVNAYEYLNGTGDNFGTRITKEKLNNI YTWAFDNNLSVSKQKGINYELHVQSKGWMGNVANSMTSGTVGLGLRAEAM KISLSGMPYSGDIQYRSWIQGSGWQGWLKNGEISGTRGQSKRLEAFQVKL TGNNAKNYSVQYRAHVQNKGWQSWVKDGATAGTTGESLRIEAVQMRLVAK ORF2192 (SEQ ID NO:210) VAEAKFEAALIKKLETEGWTYREDLSNVSIKKLEEHWRDILNETNAHKLN GVPLSEIEFGLILQELQRIKTPYDAQLLLVGAGGVGSIPITRDDGSSLEV EIFYEDDVAGGRSRYEIVNQVRFDNLPKGLTTKRIIDVALLINGIPVVHI EEKDEHLQNQWRAFEQLKGYHGDGLYKGLFAFVQVQVIMSQHSAHYFARP NAFEQYNKTFVFGWRDENNKDITDAFEFIHQVMSIPALHRLVTVNMIPDA SNDNIMVMRSYQIQATREILQRMKEMEASGLVQKEGGYIWHTTGSGKTVT SFKVAQLLASAPRIKNVLFIVDRIDLIDQTLENFKSFAYAHFKNRIKKVN GRELKRELKRKGSSQILLISVQGLTKAVKKGLENDDWNVIIMDEAHRSAS GESVKLIKKALKKTTWFGFTGTPNFYSDEINDVKTTREISTHDIFGKRLH TYTIKDAIGDGNVLGFDVTYFKPHWVVEHPQEDFSEKLYEKEVYQSDVYR QEVVKDILDNWTKTSSGALIAGKREENAFQAMFAVSGKQAAVNYYNIFKS KGSHLNVAMTFSRDESNEHGTKEQNEALKNAIKDYTEKFNVASILDAKDP ARAYMLDITKRLARKRPYNQGKEEDRLDLVIVSDQLLTGFDSKFINVIYM DKMLKEGMLIQAISRTNRTFDLNSKPHGKVRFYRQGDEMREFVENALRIY TRGGNDTLQEAEEETKNQLPKDLENDDILAKPQSHQINELEEAILRLKEL AGDDFSQVPRGQNDLKEFVGLALTTQTKIQQLIQQGYELGSEIEELNEQG EATGRMVRLNISSIDEFGALQARLYDAKEKLPPEERPDLTEIKIGIEFYH HEIIDYDMLVELLNTFMDEKNKSNKDAIEKHIVPMDEESQHEIHGIVDDI EAGHITEHFTTDSLQETRKKYRTEHRELKVRRWAANQKVNGNRIVEAFDL FLPGHTLIDNPKLADIVREIEEEENIGFFEASDFEEELMAFFNSL ORF2217 (SEQ ID NO:211) MIRVVDLFSGAGGLTLGFQNRIINNTFLPMSDYNILFANEVDKHASEAFS LNFPQIPMLNCSITELTEDYLDNHEIEYSNIDLVIGGPPCQSFSTVGRRQ YDEKATMYKEYRRMLSFLQPKVFLFENVTGLLTMKNDEGEPVLEDIRKEF GDFSDFEIDLTYEIRETVLNAKHFGVPQNRERVFLLGIRKDLEIKQNWEF PERLLFEDDFLTLEDAIGDLPALRNGERKLAYDGDPYTPYQNLMRNNSTI LMDHFNGLNGEKMLRIMETVIPGEGKKYINELVESGQLDSKYYLTSGYNN TYSKLWWDRPSSTITNNLSTPSSFRCIHPIQNRALTPREGARIQSFPDTF QFVGSKEKINSQIGNAVPPLLAIVIAQEIYNFFEENNWI ORF2247 (SEQ ID NO:212) VSRIDIAELNDFLHGLRSSNAEAKAMIRKIKEAAMDYAQDNRLKGEAVST SKRYFSSTYTSICQSIIEALDESEERLAQYIREFGSQVDSSPSARIDAEI LQEAMAKVSQLQRKEEDLHRQLTAPNTKPDMQQVYAVKSRSVHTQLLKAI EKENILERYLAFEQSHGQFFSALDELIQATGRAVQELLQHVTFNDKTGTY SVPKSAVNSLLLMKKALDNARTENDQDPFPKAFEDYTVLAYTYVNDQGET VTMWLLEKDGKRVENKELQDFLEKHGQELDPLLYTNLSGEELERKVNDSW KEGINYLNGQKVSGFSGATLRSSAYVASLKDWTDDAGLTDMALGLGFGIA AARNKAIIPKKSSGLKFDDIEKLENHFTKHGGEFKGAYSNINEYLKGANN VIKNGEKVQYNYTLKDGTTELRTGYVKFMGNTSKGKAKFEFVGTNLSGDI TTYHVKRGEDVYKLLNGNKHINVINPIE ORF2291 (SEQ ID NO:213) MKKFSMRVVLIISVLFIAFGSANVSIAQEMDTTNKLPEEELGSLYTSNLI TEEVAQDKPAEVEQLEEIPTTDELMQNPDVLEQPVADSDDPDLTVVSSGA YWTIYRNTVNGEYSLHMFGNVPSSRPTAWNSYLKSIKHIEIEEATLTGNF ASYFDNSAFPALESVRIEQCNLSGVTSFASAFYSSGIEKVIIRDNDYPTA PSLLTTQSMFGYANKLTELDVSGLDTSAVTNMQNNFQYCRALEELDVSHF DTSSVTTMRGMFQYCELLDKLDVSNWDTSSVTTMMSAFAECNSLEILDVS NFDTSSVTDMTAMFQNCYALEKLNISNFDTSSVTKMYANFSGLYEVGKLD ASNFDTSLVTTMNRMFQNCKSLKELDIGNFNTSLVTDMDRMFINCAALKS LYLDNFTTAKTMTDMFTGTTSLTYLFVSHNLSTFTGLENTSWYDEKNWVQ FSNLSQLQTYHRKQSEPTGYRKGEFLSLTMDAMGGEFEDAEEQKVQSKIS GEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWIENYT VIIPASISLNETSELKVEGINRGDKNLSVGLNRTATSISESNKLTLSNTA DATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAG KYTGNVVFSIKYD ORF2293 (SEQ ID NO:214) MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDNNGKKQKD TSGEENTIAIPGFEKVTLYANETTQAVNFHNPEINDCYFKISLIHPDGSV LWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEI NLKLVVV ORF2336 (SEQ ID NO:215) LKKRWIIALAIIVITIFGLGVKFYMDEEKLNKEMMNVVYSDEAKQVFEKR LTNLDPNAFTEKGIIHSYKIEEGSVEHNPMGGIEVGLIINNDSELNVSYT LSKNNGELSGGASVVSEKLSKLLGRWEE ORF2372 (SEQ ID NO:216) MANLKVIENEATILASIPKHNVDYNARVMQSVSVDYERDMIYWTQQYSGK KMTDAGAGESYNITRTDLKGNYIDQMWCLNGGHGTNIALDYNLESKKMHI WSAYKINNKWEVVCYPYESNKILKGTESSIFISKVESGSYNRISGDLKND MLVFHSGGDPKTFNIRIVRASSVREGKLEVLYKVKATEANDAYVYQGCAL DFPYLYTASGTGGVEEPKQLTCVDIVTGKRVYQTTFKFNTKANQTTESNF AEPENVCVYYKNNQKHIVVGYALGGAGNRNNRAFDLVENNSENIETEIES LRNLIISRKRTEVIFDQSTKGDMTTNFKLRETLNNFDIIQVVLESGGGYT TASRLVSPKLFEASKSFIFASSNIGDASGNNVDMYEYAANFNDDLTSFKN DRAVKIEVSNNGTVRGNITNNGIKKIYGIVL ORF2375 (SEQ ID NO:217) MKKFSMRVVLIISVLFITFGSANVSTAQERDTANKLPEVELGSLDTSNII AEEVTQEKPAEVEQLEEIPTTDELMQNPNVLEKSVADSDDPDLTVVSSGA YWTIYYNSANGEYSLRMFGNVPSSKPTAWNSYLSNIKHIElEEATLTGSF EAYFRDNVFTVLESVRIEQCNLSGVTSFRSAFEGQLALEKVIIRDNYYPT TPTLRTTENMFLGCYNLREFDVSGLDTRAVTNMRAMFQNCTSLEELDVSN FDTSSVTTMQNMFQNCTSLEELDVSNFDTRSVTSMAYMFYRSAGLKELDV SNFNTSSVTAIQGMFYDCSSLEELDVSNFDTRSVTSMTFMFLNCANLEEL DVSNFNTRSVTSMTYMFGGCTSLKELDLSNFNTSSVTAMYNNFQNSTSLE ELDLSNFNTSSVTNMSYMFQNCTALKSLYLDNFTTPKTMTDMFIGTTSLT YLFVSHNFKDFNGVENTNWFDEKNGVQFSNLSQLQTYHQQQREPTGYRKG VFLSLTMDAMGGQFEDAEEQKVQNKVSGEYWEEVVPVKEGHYFDGWYLDR NFTNKFDFSLPVAVSTTIYAKWVENYTVVIPASISLNEATELKVEGINRG SKTLSVGLNYEETTISESNKLTLANTALTTVQCLAPLSWDGSETNPEKVI LTLAPGSEITEGDAVMAIEAPENIQAGTYTGNLVFSINYE ORF2440 (SEQ ID NO:218) LHNIFFLITLFPGMLLLLTKWIPVLSRKSTFFQYLLCLFLITIMNSLFFR QQFVVVLSLICILFLPFILFFVEYIFVERQWKKLLTIYKKNKIIIQSIVW FPVLEEIIFRFFIYQYCELFDFSNIQYILLATFSFVIAHIFYQGVSSIVK ILFSFILSILFLLTLNIFLTIIIHCIFNFLVYIVRTSKYENHRNW ORF2462 (SEQ ID NO:219) VEKPFLTVVVPCYNEEEVLSESVTQLTNIIEKLVMSESISDKSQIMFVDD GSKDRTWELIQQYSESNEHVSGLKLSRNYGHQGALLAGLTEAHAYSDCVV SIDADLQDDVNAIIEFIEKYHEGYDVVYGVRDKRDTDTYFKRNSALAFYR IMSKLGVNNVPNHADYRLLSKRALTEFLRYKEENNFIRGIVPLLGFKSTK VFYNRNERFAGESKYPLKKMVLFAVDGITSFSVAPIRLLLVLGSVIFMIG VVMGIYAIVQKIIGAVVPGWTSLIVSLWLIGGIQLIGIGVLGEYIGKIFK QVKERPRFTIEENVFETKCKENKISER ORF2541 (SEQ ID NO:220) LKKFVLIFICFLTLTTIVPWNTLETKAASTSWLEQELDGNEAFITETERV LSKNREDITLADLETIQELDIYGDASSIPDKISDYKNLNTLLALNGTISE IPTSITKLTKLTRINVDNNNFQEFPMILLQMPSLSSIEINRNKIKEIPSE ITTLSPHLGSLDVRYNELITLPDNIFTTEWESKLSLLTTGNQLVSDIPAD WLDNFNQADNMLEFYNNPPNDYHQKQDQLTYSGARIEVPLNTDLKTLTPD KTKLGLKSGRTLFEQHEFMYYDDGTSNNILTNGVATATGNGYITIKSTLS TNSNPFAKVRVPITVTPPVKGGDVTVQYKDTTGVVLADSITLSGNVGENY TTTAKTIDGYSLTTTPTNANGTFSTNPQTVTYTYKKDPIAQPVTVNYIDT DGKTIAPTETLSGNVGENYTTTAKTIDGYSLTTTPANANGTFSTNPQTVT YTYTKDPIAQPVTVNYIDTDGKTIAPSETLTGNISENYTTTAKTIDGYSL TTTPANAKGTFSTEPQIINYIYAKNAETAQPITVNYRNSTGQKIAKSEVL TGNIGESYSTQPKTIAGYTLTTIPPNAKGTFTTNAQTVTYMYTPIAISAL PVTVNYLDENGKEIADSVVLNGRVGEAYNTLAKEIDGYTLIKTPTNSNGV FSAEAQSIDYIYRKNKPVVIVNPPIKNPIIKIDSSTNVIKEETSVLPKTG DSNPYNDFLAGILLLSSAMFLWKNHK ORF2568 (SEQ ID NO:221) MKLGKVGALLLGTALVFQAPFQVFATSVNGEEQVKKEAAAPKISVNKQTL AATSDLEQTVGEAITKTIHLQDQALPNNEWGSYISDVKVTLSNMDGISYD VKYGPLSEDGTHYQYADITLSGAPTKAGTGSISLEYYDGAGNGGVYSYSV NTKSKTTIQYVDGDGNKLAEDTVKTGDLNTAYTSEPKTIDGYEVDETKLP SNQNGQFAETNQTVTYIYSKTKSEVNKGTVGISFYTPDGSRRELKSSLDL SYAYPDGVPTDTVTFGDLAKNTTYKDLRNTPDAPTLLWNDLLHYMVDYMN GDIDAAQFEEAVGLTPANFDLDFISRNFEGYKFDEAMYQENLSKLVTFEQ DGDQVDLQVPFKKVEVGADITVKYVDTAGNELASVETLSGDVDDNYTSEA KTIDGWTLKETPNNATGVFSKEAQTVTYVYEKNDDTDVTPAPDNSADTND DSNSSDNTATTDDNSSSAVKEKAQTQASSPKAGKVTTQESTSNKVTAQSK ESLPKTGDNVLESSLLVGLGMLLLGGLFVFLRKTRKVK ORF2646 (SEQ ID NO:222) MRPTNVYTPEDIYLKDRTGFNNGNIAYQYSIYRALWNDDVEIHADGLSSN PNLAEKINENYDLYVMPLADAFRDDFRPVLRNYTQLIRKLKIPVIVTGVG LRANYEPQLDEGFSFDEDVTNFVKAVLEKSAQIGVRGQITADYLKKLGFN AELDFRVIGCPSLYTFGREIKIRDFHLTDQSTIAINASPTSSEIAINFLN NMITTYKDYHFIPQHLDEFHLMYAGGPDISSDINGYPTNIQHKYYQEGRV KYFTSMPSWFDFVKKVDFSIGSRLHGNVIPTIVGTPNISFVQDARMRELA SYHALPHVTIDELEKTNNLQELLTKVDLKSAEKVQARNFDNYIDFLDTNG LNHIYKYDKNRKSAPMDELINSITFPTSPDPISILNPQEMLNRVKISTNL LKERHDFSTRYRVNLVNNQLTQLKKTTSEQNKKYQQKITETQEKNQQLEK QLTDTKQKLQLTINKNHELTNKIRHYQGTLNRKSVKTTLKVANSLANLKK KVSRS ORF2666 (SEQ ID NO:223) MEMKKLIKCTAPIFIATLIILPVSPSISALANETSEISEGINATEKTIET EELVVEEISNDEYQVLDKETNETTSIEFSKNHMQSTITPNDGTIDTMIKK DNLIYLNGEVIGEEVKEESRQLLKASAYKYVTTFKTKMSLKKTSASIAVS LAGLLGGPVGVFSTVAGMLLTLKSYAPSKEVYIKIKQYYNSYSREIKNDY SIYKKSNYTGLLKTFTHKYRPYG ORF2758 (SEQ ID NO:224) MVIVLLYNAKRIETVFLCLLLSENAVGNQAFAIDFGKIEDIDVAFKNTKR YKLFPSCTDTFKENYFLGSFSNMKSAFFLSK ORF2759 (SEQ ID NO:225) LQIKNKANLITYSDSLGKNMEELSKVMETYFEDAVGGIHLLPFFPSTGDR GFAPSDYTTVDSDLGSWEIIEKLGEKYYLMFDFMINHISRESLFFQDFKK EHLNSKYKDMFIRINDFFPPGRPNEKDLDLIYKRKDKAPFQEVEFADGET ELVWNTFGEEQIDLDVTAEVTKEFIRQTIKNMAAHGCSILRLDAFAYAIK KLDTNDFFVEPEIWDLLDEVKAEAAKYDMELLPEIHEHYSIQMKIANHDY YIYDFALPMVMLYSLYSGRVERLANWLEMSPMKQFTTLDTHDGIGVVDAP LLLTDEELDYTSAELYKIGANVKKIYSSEKYNNLDIYQINSTYYSALGDD DKSYLLARVIQCFAPGIPQIYYVGLLAGKNDIDLLEETKEGRNINRHYYT IDEIKNEVKRPVVKALCNLLRFRNTSEAFDLEGSIEIETPSSNEIVIIRK NKTNKITATLKANLSTKTFQISENERNILI ORF2763 (SEQ ID NO:226) LKKILHIVIALSVICSIILVPVDWSAKAGGNNKRDDLIKSVSFYNSNGQN VTAKENYNEKLNYFLEVAFGGNSFQKGDYFNITLSSDALLYTEKAYDLKV DIDPTAVTNEQVVGKVTVEKINGSPTLHFVFTEDSESFFINSFDASFKIQ VMPAHGDKNVINLSYSGAAKNFKNIGTSSVEWNVNMADDWPPVGISDFSK ISGDLYHAILVYEKPSSKVNYETEILVSYPLFEKRIPLGNVQNIKIEVWD EAKEIYRVGVAGVDYGTITYDVGTPFVGGPIFQMNCTIPFKGISTKTRVS FDIDTNVDGKPGTTDPYLVSLSSVSSATKSLEFYPVNNADTKMTAAFFGK VTTRFEDELGNPVTFDNYSTVTTPGKVNQDGKFEIAEPFLHNSVQNVDKH AYDTLLDTNKYKLLEVTSPNKLSETADNLSIQIKRGYQNDVLYKIKALQK PVISALPEIEYSKTVNRTMEEFLEDVEAKTDIPADIDCDLTNVKWGVPGD YLVLITAVNEDNQAADPVPVTIKISKNPAPVITVDPEIIYDKTVTKEEST LLNEVNARTNDGSTITSNINDKVKWGVPGDYEVTLNAVNEDGVAAESKTF IVRILKSPAPIITVDPEITYPKTITKTEAELLQEVNAQTNDGSPLVSDMN DKVKWGVPGDYEVTLNAINEDGVAAEAKTFIVRILKSPAPIITVDPEITY DSSVIKDERELLKDVHARSSDGSVITSDSQVKVKWKKTGSYTVTLNAVNE DGISANSVQFTVHIVDAKAIPVVIEEKPESTPKPDTKEKVVIKKEKLPKT GDTNTKTILSGIFCLGAWYLLRRK ORF2777 (SEQ ID NO:227) MKNQFTYLINNKTTQGMFILILFIPCIEIVQLYIMLKPDAVNIHPAFAFF LAGSSRGHITQILLLWFLTVLSLLLGADSPIQEYQTGVRNIIINKIGKKA YILQKLAVSFILCFITMLTTLLLNFILVSIVFLGGTYKMGLNGLGSLNTL FDFSIQNPYLADFGFGFMACLMAGMAGLIATSSSLFFLNKKFAYPAAFFI WFLMILPNNSIMFIFQPFTEYGFEIILPIFLVFSLIVLIIVGVLYLYEVK YVKE ORF2778 (SEQ ID NO:228) MLKSRYFLLIFSMFLFFSVFWFTQNNEYLSFPKNRELVLIMNGSLYGYIS IKSLCLMLVFPYLIFLLLFSKKEQIVALAREKNRLRFYHKILKDTVIATV LFVGLYLSVNLLYSFIFLSNKLLTATHFYSGIFFTSCYLFSFI ORF2779 (SEQ ID NO:229) WNFFYFLLLVLFYLAIGFLFRIIYDLTTSTGQALIFGAFVICIVYLIDWI ILEGIYWTPLHNLNFFDLWLQNGSISSDIPFILIPNAAVAFILYLISSNT FIKKDFY ORF2780 (SEQ ID NO:230) MKNNKLIILVVICLFLQAILFMAFDFPFKTLPILDGFPVGLATPVVTRLL LYWYLPIIAFSFYISGNLKDLLSSYGFLQISRNYKKEYWLMKQFLKLLIK VILFTSLQLALIFIFTPYSIYSTAPFLYLILGYSIMLFTIFSLQYLLELF IDAQKALLLINGYVIISILMADLIYQNTTVTWPYYLLLPNYGMGFRTGLI PFTNTSTLLISVPTSLIILLVVLLCVFIVAIKKFKTTDIL ORF2815 (SEQ ID NO:231) MNEKQNEIPFDFSYYALELLGKGLYKNRWSAISELIANGIDARATKISLY MNLIDKEKAVIEIFDNGTGMDYDDLVSKYVHIGRNKRDEELDDVERNALM GRKGIGKLAALNLSQKYYLISKTRNESSLWCLDATEVNKSDTPKLKRVES KSVALESIEHWKENSTGTMIKLTNVDMTGFGIQSMEGLKLKLSDFYLLNQ MSCEIEVAYITTKEEKNNIKFKKVEKKVAFKNFYGFFENMENDKYKASLA LTVRFPSVYETITEKPRKLYFDKQNFPEIKGKRRFKNKNGTLSEKEYEFE LKGWIGIHTSTKITDDAERNDITFFRNNTYTPNKLRLYIRDKLIVEDFMA QYIRSTQATSGYIEGEISFDILDVNDLEDITTSDRQGFTHEDDRVKLLID ILKPIVNLLIRERNKMGGQIRKEEEEYREQEREEIRKQKLVEAIKRKEAE DQKEAAEKAKAKVNQENNILKNRITQKDIHLGSEKKRNIFLKSSLSEDKK SFSQKARMIRINVKTIENTTSFLVNEITKEKPKFNIIKEKLKIISHNTNR IKRIISYVDSAKFNIDNEKTEGDLIGFFEEYVVNIANQEWEKPQGKVVNP GKCSLIKVFSPQDIGVLIDNLFSNSSKNKARNIIISIKEDKKYCYLNFKD DGNGLPSHITDTAELFEFGKSYTIRGTGVGLAHIKDIVNDMDGKVYIPKD NKEGFEVEMRLTK ORF2817 (SEQ ID NO:232) MNKETERKLAASLTSQSIEILPFIPYFLQDFFELGSSPKDITYLIKQHMP LSAESNFLDLACGKGAVSIGIAKELGNPVKGIDLIPAFIEEAKCKAKEAQ VESLCQFEVGDVNKSVQNEEKYDAVIFGAAADILGNPAETLEKLQGTVKE GGYIIIDEAYVPELAHNNQVKYQNYEYLTRKEWLNLFEQNQLQLVEELEG TAEVDFELEKQHLLARANELIQQYPEKKALFEGYLKSQWSEYDDLEEYLI AVTWILHKK ORF2819 (SEQ ID NO:233) MPKLVTGYERQQTKNLIIEHTSHLIYIKKGIQGFTVEDITRAARIGKRKF YTCFPSKEACLFEVVEYSYQAQLEAFKKIMEEKGSLKSKMTRFLKEVYLS EKSINNYFSPEDFHAILQKLPPTYTEREERMTSEVLETANTYIDLTPAQW EALVMLLDCLTYTATRSYVETAKKAKEETLDILIHSIADYVEKQTQC ORF2836 (SEQ ID NO:234) MKYMVKWRGFFIVAIIGLLVFQNVSPVLATIVDEKTTMITLKIIKEDKDT KEKINGSSFEIKNKKTGETKEVSITEHGTIIENSLSEGEYIVKEKKAAPG YTLDEQTYNVTLADKEEAITSSSTKKEAEKTPSVTEQPSKKGNLKAVITD NIFTAVKVENGTGNELGATNRIKNGGAVVLKMNFTFSGKNYKAGDTFKTV LPDSFNFGTTNLTGDFLPSTEAKWDLNASTRELTITFFKDGVQEGNYDIE LSTALKSFSETEKTSQVAVFNTAGGNTVYQLEIIPEVDKATQVMLEAMPS KVNPDKATVDARFNLTKETSELGELRLSDTAYGGSTIINRNSIKVYSTDI SAKGTFIGSKQLLTENTDYELIYAPSGLTIKLKEGLKAKGYQVTYERSID KTNSSLSTIGTSATTVGSSGMLSNGSMTISVTIKAYDHLIKKAVYNPVTQ CIDWTINVNYDLANLTPGTVLTDVLTDDNVSYVADSLKIKRVTFNEESGE AVIGDDASNDWTVSTISDNGSFNNNYKKTDEKAYQVTYSTKLTDFSPRKI KNEVTDEKGVKATENFDFKPDLLNKEAGEIDYYNNTMDWTITVNSEGINM QNINIVDEFSTGVKSLVSYNVYAYPSDSGYKLLTEGRDFTIQKDVSPAGF KIKLIGNYATTDNKIVVKMKTKIDLTDGAKTLDNKASFSYFDGSLTQYSE TVKAEATPETSILANGGKVGKWNPATGEINWIVSVNAMGKKYDKLVLDDE FLDGTTFVEGSLQYRNVVNSSELTDLSIPLEIKGTLAQVGDANYPTKIDT SANKIHLEFGNLDTNRVFVKYKTKPKDNWFFSQWVNNKAIVSDNGADEQI YETKEFAFLQNEVIKVAGNIDNVYGNKVNWNMELLNISPERTLSNPVITN RLEQGNTGAQFIKNSFQVINTKTNEPINEENYDITFEGNTFTIQFKNYTA MAPIKVSYSTISLLSGPISNETTVEAEDFSNVPMFFKKPNAAVSPVFTVG SGSGIATIGTIKITKVDEDDTTKKLEGAKFQLYTLDGEKSGQEIKTNSEG EILLDGIQSGKYKLVETEAPEGYNISDEYKEGKEITVNSSGEELLLTIKN ANKKGKVILTKKDSASDEVLADAEFELQNAAGSKLKEKLTTAASGNIEIT DLAPGDYKLIETKAPAGYQLDATPVHFTIDFNQSEAAKVSKTNTAKTGTV VLTKKDSATNTELADATFELRNEDGALVRENLVTDDNGEISVADLAPGDY KLIETKAPTGYQLDAAPVHFTIDFNQTEAANVTKTNKKKIGTIIVKFIDV EGNQLNDEEMHTGNVDEEYNVKAKEIVGYTLVKDSANKKGMYKETSQEIT FVYEKKANPIIVEPTEPSKPTEQLTESATVAEPKPIKQNFKTTNKSTNNK RKLPSTGDEFPYTMLFIGLFVSVAGVFFLKKPKQIK ORF2847 (SEQ ID NO:235) MLDSTKLDSTKLDSTKYKTKNYLNFDYRVKIENVESYVTDHSKIGNHSFL PLIRYVSSFEKRIEEKNPEFDNRPIKTKDRVIMYAGHMDNFIYKYYAEVL NKDFYNKFCNEKGIDDCVSAYRNNKVGKSNIDFAAEIINQMVNYKEAYIL VGDFTNYFDKINHELLKKHLAEVLNQPRLSKDWFNYFRSITKYGYYEKSF LNEEYGSDESIKRSNKKSYFENISKFREFQKNNKTLCNKNKFGIPQGSAI SAVFANIYASEFDLKLKEIADEFSGIYRRYSDDFILVIPKSDIVNEQKIR RIETDTRRVASEYKIELHKDKTGLYLYENDKIEDIISNEVSHLDYLGFVF DGTTVGIRGKSPYKFYYNAKKLITFAQKVKVKKELTDLPYKKKIYGLCTD LGKNYNNHGNFISYAKRAQKKFDEISPNTNNLIMNQLKNRKKKIEKMLGY KIHTKI ORF2848 (SEQ ID NO:236) MKLIITLIIILSNWLIQELLMILEVNLKQFLTDNADKVLLDCLKHHILYS KNTGMLILSQNKHFLKKTMYNFNYLSPTLNKYYISYTKRALS ORF2854 (SEQ ID NO:237) MKFYIKEIQLTDSNTWKLQGFSEGKINSIQAYYNEIREYKHPEQKLNIAF TQDKNSFTATISVDELASLSLPNNQTVWKFKVNNDYPYTHLITDGPIINK PFQPENSLYKYHFDFPEGILTLVSKPIELLASIEEYKLDSDVMSGSIKIK SPLPSNQFNAKLIFKRRPTPSFYLFEEQQQSFDLGLITENIVNFSIPTKD LSTAFLVDNTNILDAIIEVSSSHNKTGLSAFISIDADMKPAIPREIKIAA PLFATLRSYITGSNRLSFYFKKNIQGLVSLSQLKETKKDLTLQFKLENSI SEGQIVAKRADKKANTFEYNVEQVWPLKKGITKYTAQINKNEFLSGPINR ALATWDFFLRLANMPDLPILAPNTIDFSSSGFFNVANNEFMAQLTRNDSN NLACLTAVAPKIKQDITKIAVMGTCFSRNAFNSSPFFNPDYKAFFECSFT QFHSSIISIMTEPANLINLDKYTDIKKSEKPFIEDDWKKDFFTNLKNSDA DYFLIDLYPDVIRPVIWLNNNSAITLSYVIEQSQLLNDISYERILDHIDN ETYFNEWKGYADQFIEKLTEIIPTDRVILNLGGFTTSYYDEDGEVATYKN KMAIEKNNYFWERLNNYFLSKLPEAKVIDFSKKGYIGDFNYPFGHSFSHF ESPYYKDFLKELIYITKS ORF2884 (SEQ ID NO:238) LAFIRKNSFLLFLILFLMSSILIHMFFYNFLTDIIVTVFLGLETIFIVII SLEIMDVKKIRKRTKRIIEIYFLTLLGITVITSYLFY ORF2885 (SEQ ID NO:239) MIEFIIDVSINFITFAICFIPLLLSEKTKGILEIVGASILFAGIMIVGTG IFISSSETLKSYIYVILVVQIIILCSELILVLWSKSKGKSTILSILSAIL GIVALGIYIYYVIASFIY ORF2886 (SEQ ID NO:240) KQFEIAADYVYQSKEIIFIDIIGDETPAIGIIAENDYEGLEITLVDDEGR LDGTCWIKKEDILALRFGGSVEQDLMNKLKK ORF2887 (SEQ ID NO:241) MLDKQQLYIVENKDIPNYEVDSGITGAEQNYIYNFKNPIPISEQELQDIC DTFGEFMVSAYFLVDIFGPYEELPGDKKNGYKKVVLADESMEIKKKMFHL FLEGDAYPDANKIFLFKEKKELNARKNMEIEDGMIVISPVLDVTAIGIFS KGIDLAQFFK ORF29 (SEQ ID NO:242) VLQRRFWGIFCFAIFLFLFPTIGSAETSGDYEYTINGNEATITDYTGQST DITIPTTLGTNNEYTVTAIGNGAFKSKRLTNVTIPNTVITIGDGAFTINS LEQLVLPNSVQTIGRNSFSVNKLEKITYSTALKNIPSQAFLANNLKTVTT PATVESIDASAFENNFITNITIQNPNLQMAYQAFAAQTVLSTLIVPSNHI LPIENYIQFQDASAHLTTDNLFITDLANGITYNQAEKALNFSAEPLESTF SLFTGTNRFDSYYDISEYGPSGKPFIYFKYTKPVLVSYKDASGNELATST RLDGSIGENYVTTPKIIDGYTLKETPGNATGQFSETLQNVTYIYEKTAVQ NGTVTVKYQDESGKTLAKDTVLTGEVNNTYQTKSKDIAGYKLQKVEGNES GTFSTTPATVTYIYEKIANSDNTNTNGEMTDNTTLSTNDTVISSEATKKV DKNTSNILPTTGDSKDALFFALGSLLTLLSTSFFFFKRS ORF2925 (SEQ ID NO:243) VSRIDIGEIQDFAFQLPAANQTGRKIIQGVKTTVTNYVEDGSLKGKAVEA SKNYFQMTYIPLCDTIIEANNESEERLKRYIQDFHDQVDLSPNAKIDADG LYELGQMIDRIESKKEALYQRMNSSTEGQMQTYRSQLATAYKQENILEKY LAFEQSHGAFFDHLTDLVQGIQQTVRELQSNIQFDSQTGSYDLSKLNFAT VNRMRKTLGKASATDTTVYNFASYSKVKQGVMWILSKDGKVDIKATEAYN TASFNGELPKESNQATEEGELLKATLESLKQNKDPITGQEIIKAQSFGIL TSLVFGYTTKGYQGKKLTISKNTLIKLRQADKTVIERIKKTSRIDYEEIV KKGSKMPKHIIVENKQSLPGKANPSSSADLLNPDGSVKQRRYYDEKGRAK EDIDFNHSDDGTHEFPHRHEWDWDRKPPRKPSK ORF2927 (SEQ ID NO:244) VDSNNEKLKQQLQTLQKQQKDAELSLYMLKHEQNERIWLEEDFERICYEE RESLELMREVWQGDQARNFGYYLEDLQADEKNKWCQTFQAEEEKRQEKIN TYQKNIYQLESKQQDIQKELFQ ORF2969 (SEQ ID NO:245) MNSNEISEIIIQQNKGKTIIKLLYTLPILLFGIFILFKVKESLLLGACGI ILLVIVAPTYFTVAKHFFSGKPLLKVDQDGIEGWSKRFKWWEIEKVALRR DWGAVYLTVYVRKNGGIHKYNINTKEIERSATELIKQIGYLKNKYE ORF2970 (SEQ ID NO:246) MIAITLFLSGCENGDTEKTDTEEQTKNVEDEGEKVEIESNEGKPQHEQLI KIELPPKADYLNDETLEVYNQAKKKYDQTNQLITNDSITVLVGDYGYYDS VWGSLDCSAVIKNGTNSSIKDLSFEVSVEDNAISGKTFLNSEALPLTKTQ IGDFEPNTGVPIVIAFPEKNATGEGEDKKIDTKNVKIHISNIQYKVEK ORF3102 (SEQ ID NO:247) MSGKIKFNIAEAQNISLELKIAAGRYTQETEELLKVLKNNSLCDKDQDVV EQRGRIEKNNQRLIEYEKFVNTNLAKSNSVIEELFMSVEVLYAQQVSEFR NPNSAGYKELMGNVKAISYQKISQISGLGEMLTSKGSVGAIKDIRDTLLG TLVDDTYLKLIDDTVEYQGENKNITDLYGDKISKVGSRRKKLDTPTKYLS TAYLISDTLKSFNSYGNSKDSSRLAGDLTGIAITKGADFAVGKLATTALS GFGVSGVKGAIAGAIISVAADKIIDPTVEYVKESKVEAKRDDWETKGIYK GWKKIRDLKLEYTVGNYQAS ORF3103 (SEQ ID NO:248) MAKEIKVNPDFLKKVESNVTNYIDAQKEVSVELLAVRTNLASNFSGIACD EIKNYITELMNDLEKEFGVFITKNHEKVKALGESYKELDGQLGQTFNYGM ERTK ORF3132 (SEQ ID NO:249) MKKLQWLTNRLFATSILLITTLFIIPPTFAIADGSKVSFYEYIYGAPFRW LTVISTTDKKGAFTEMFFSGNEGITIQWPNLMINFLLIFLAITIIFSLAK KLYDKKNVKKDNP ORF3135 (SEQ ID NO:250) VKIDLEQIYTLQFTMGLRYRPMQIRHNIKLLLVALLFFSWIQGDFMSGLS GDLSMFRVDMSLIVILGICFILLNPIKLAIRFQNSNICCIFFVFNG ORF3136 (SEQ ID NO:251) MYINLKSSDGNVITTKVGSCWTCVFLSFFGPLLRGDIKFFVLYVILDGAG LFITLNYDRDIGIAIMAMVTLLFESNYNTWFIRGKMNNGWEPETEKDREI LLEKGVIKTEV ORF3137 (SEQ ID NO:252) MKSRNWLKGLGVTMIVVTLILTGCGNGDAEKTDTKEQTKSVEEEGKEVKI ESNEGKPQHEQLITVKLPPEAEYLNDETLEVYEQDKKKYDQTEQLITNNS VTILLGDFCYYEPAWSSLTCSAILVNGTDTNIEDLSFKAEIMNKPMSGKI FSDDKVPELTKAKTGKFQPNEGIPIILVFSEENPKNEENAEPQKINIKDI KVKIKDIQYKAVK ORF3138 (SEQ ID NO:253) MVSPMPDKTVKMDKGSINPKLDKLISSLDNFDNINKKMGTIVGSQEISGE AADALSESLLVLVSYGEQYSLVIRNLKEVIVDYCKSVEEIDKTAANAVSK GV ORF3140 (SEQ ID NO:254) MIIIKNFASKNIRLIMALVIGVLVFAPVFHSKAADNNIGFDFKLKPNCAN SGSSSRYRETSSVNNPWKVRLDNSTEGKGTIASFWLGTYNKNKNAVQGST IMNVKQGAKTRYCGAYKVANKNTTYLAAENNNYNSKTYYVDGIWDEETW ORF3141 (SEQ ID NO:255) VLTNINYSFEPGKIYGVFGKNGSGKTMLLRSLAGLIIPTSGKIFIDNKEL HHDISFPPSMGIIIENMELLPQFDARTNLKILSKIKNIASDEDIDNAIDR VGLSPHIDKKVKKYSLGMKQRLNIAQAVFEKPAVILLDEPTNAIDDQGIE LINQLLLEEKKRGATIIIASHHKEDIEPLCDMSIRNDQGKIIHD ORF3142 (SEQ ID NO:256) MTKTKFVIFIALTVITLLLFLVPKGIQYLKSQNPELLNTAESIKLQAGEY TVGKDIKVGIYDMQVTKGSLSYYSTRLSKGDEIIGINLLDANKLYFEGSG EVELTPAEFNPIKPSANIFTIQHSGSYEVGKQIPAGKYSLTYTIDKSSKK KPFIQILPSYTDDARIEIQFETKPAYNINLKTGEILTVSKTISEELDTMT VLLKKN ORF3144 (SEQ ID NO:257) LGNYVKISQDNKPIGWIDSENVIDEKTMDSIENDEESIIPEELIDKVNDY VTIENNEFVLSNKAEDVLTSEEFVEVEGQIDRTNAEIEADETLSETHIEG NIIVQEIYEDEPNQLLKASKKAYIKAKYTWWGMQIQFSHKAVVDFNDFYW GAGTIGGLGANKRMGKFLAKKGIKIASRYAVCLSLFGGGLAWGMGKKDKG KGVNLNCVLYVPATITTAK ORF3172 (SEQ ID NO:258) MSKERCACCNCLTIDVRGEFEICPICFWEDDAYFVFDKEEIYSHYQGSSS IEDLLNIRSSANNSLTLLEARQNFNQFGACELAMKKYVREPTAEEL ORF3173 (SEQ ID NO:259) MEITLQQPTSADFPFIEWLWGDLATTEILGGPFSFPEETRNDWLKSKSQA SNAYFIIKKGTESVGEVSFRDFEKGTAHLNIKVAACYRGQRIAQKALQLF LDFFQTDCGGLVLLDEVRRKNEAGIKFLVKAGFEVIEEKEWTMVLKWSAQ AEGGFE ORF3174 (SEQ ID NO:260) MNTLYYRVSKNTNFETAAREIFDLLIETQQQFENQPRFLKVEIDGHLNEL NEFDNDMLKLQQEFGEIFLLQFFTTISFPLLTKKNPRKQINDIPNDLTIY DLKYGNPAYKLQIENYYNTEFVLEKDVYVFLEKVSNLLKKYGKTDNYKIN IENEEYDKLGLLIHWQSYMKELIVELFNSFVNGNLISNAANTRSLIEGYV YLSIIKKERNPLLVQDWFLCNLIIGSKRYDDGTREILNNTLKELFDSNED IQSRYKKGNTNNWLSTVIAKKNITFRDACEYLEEDYLYKDFQEASSFVHA QDIQTKLSPFFSYSSIYGKLYIMIIYMFKTLLLFESSLVLKEEIADLELE LIILGENYL ORF3175 (SEQ ID NO:261) MIYYKDKLKTIGTALTSLSFIFMFGLLTLLSIEKPELFYYGLITIFFIGY LIVKLILPPKEWIQVTKTAFILHKRNETKTIHLANVKRISYNFQPSRPSF GHPIPETMELFFHTENKLEKIECDFIGRTNFVALIDQFDAKLASLSEDIK NHDYSYPRDLTFGIFIFSIVMLFLIFILLFGREFLFEQIGKVFV ORF3183 (SEQ ID NO:262) MKSQQAFMVEVTFYSNARKTVPEAGYRPHFVMELDENREYLGVEIYDIEV DTLDSVGYAMCSFLYEQEGVGYSKIQPNKSFMVMEGASVVGRGKIVSFHL ORF3184 (SEQ ID NO:263) VISIQNNLEYNKLRWETLSGNVTGIWENNKFFLGSSSYPIMKYHYITANF VNFEKHISENMPKISYHLSGYGVNFNEALVSFIGESAERYTYSLLPTIII TRIIFRSYEEMTKEYKTDLICELKYINSYYSSEVCENYVTPNDTIQWIAM NSLVHSDKKVWMPLQFVTMYTEEMFSNEKRYVTSAVSTGTACHETVEKSI ENALIEYLQIDSFNLWWYGGFRARDIEIDITRNISSWFDNQVAVKKFLSK FNVHFSDVSFDKSIYIVLCEIEAKNSSDAFPKYTVGVQGGYSLDKSIYRA FMECLTVLEYNMNVTWTDKEKFLSVTQETRVIDNLDDNVIYYSKYGKPEL QYNTNQLKNDTEKVTNLKALLEKLPTISQYAAFLPITPSEFRYMNCEISR VILPELLSIHLPSYPPYYHVRYEEIGGVVNNIPHPIA ORF3185 (SEQ ID NO:264) MKNFDIRIGTQTFDNDTEIILKRGVIHKNELVINKEESSKEFVSTFKELI KKKTIAISSEDAIYNDFETLTKFGFLTISKNQTLKPLLVVEDALFDDMKS YFQEEIEILSSSEFLLKKDIRLLTENKDILQLTKLVDEKKEFLKNYNYIY LITNIPNISLLRGFNKLMKETNCINTIAFFDNENVFVTCIEHGETGCYEC LEQQILSHFDGVVTDYLVRSENNVSTAELMFVLSIIKKEIENTSIYGQSS LLGNLLHFNFNNYEYTFNTNRIQSCCSTCATFNNILFEEQNIRSVNILKE LMSSD ORF3222 (SEQ ID NO:265) MEKEQQTDDTWVLVEIVSLITNVERQRLRELSYTELEEFYERVVVEQ ORF3224 (SEQ ID NO:266) MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVG YENVQLETGKTYKYTVAYEANVDMKMTDTITGQSAKAGLFTPKSSGAELN TSYVSRTKNNVIDVADAGNKVFKHTFEFTAKENTKADIGVFLGAGSVLPT TPETTSLWKNVTVTNETPLVQAEAPVISAEDKTINQNESFNPLNEVTASD EKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTTKSIKVTVTPA AISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTV NNSKKGVYQVTYTVTDSGNLSASLTIKVTVTQDGKLIVNPSDPTKPSITK TPVEPTKIEKDPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISS YQKKANK ORF3277 (SEQ ID NO:267) MWLFFKRDILWFLQGNKWKIIGLGMLLILAILINVVNAKNASGTIADVFL SFLKQDNGAENPLTSSLNWIIIQSLPVFLFGSYFYKELFALEEFITIRFN NRMLPFLSKILLIITLMLIYYFVIIGLVVFISFLFGIRFDVQPTLLFIDL NMPLYEMGLHFFVGGIALIMLQLLLSIIIKPFYAITVVLIIIVTNCFITN FWIIGSVSNVAGFAEANNWLLLSIQLVYIILVMLIGGNIYRKTDLYKLN ORF3278 (SEQ ID NO:268) MKNRNLVRLNFDFERRKYLMLLLIFVFIIVSRLLYTRNVETDALYIVQSS VSVEVLFIILSPFCLWMNQILCFQRRELAVVRIKNKYTLWKVNATVILWN AFLLAVLTNALNYANGVIVMNSQIVQIYIYSFILFGLGLVLVGVLQNILL VITSNKAIAFFVVFLVFFFDTSTIKLQLISNLFIVNPNDLTDLLSFAGRV FCLVGGIIVLFLISWLLTEKKDMFRTSKKKVR ORF3279 (SEQ ID NO:269) MSRFLKIEFNRVFKSKSFLAALALGVLIVLIQQITVARYYSTAEENVFLY LTGYDTTGLGTNLYYLLLPCLVALAGADLLGEDRRSGLDIFSRIRGNDKQ YYFSKSIVAFIAGGVVFCLPLIMELCALMLVYPSTPLDYFVAEVPVTYGA NFSNIFYNSPLTYELIFLVIGFAYGGLFALIGILVSFFSSSKYVVLLSPL AIYYGVWIVFSLIGYPEFSPFGFLTPKQGYPLNFYIIWVEFLLLLVVIIM GIIWRVKNEKS ORF3283 (SEQ ID NO:270) MYKDGYTSRNNTYYGEFYGHYAGGKDKFSYKLEKKNNKNVKSQLIVDLFV I ORF3291 (SEQ ID NO:271) MLTKEILPIGSVVYLKESLKKVMITSRLITIQGDEEKEFYDYGGVVYPEG TKDDNILAFNAEDITDVKFRGFVDDDEVVLVKRMREWQKEEFGVSPEEED EILEL ORF3316 (SEQ ID NO:272) MRYEAKIISENPNIEEELKIKIKDIELLCFVEEYKCSVEVGQEYIVELET VVFDDLDIEKSTLQAKEITQVADSFAYFIRGVFHPSSKKIDSGIEIDLAD EDISDFWYLENQFVALNVDRFNIDVIEKVNK ORF3324 (SEQ ID NO:273) MARIEYEEKIQKSLLVLYFRGSTIQSICREYGIPRYEFHKWMKLHDADKL ETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP ORF3325 (SEQ ID NO:274) LKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQE IPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRRSKKK E ORF3326 (SEQ ID NO:275) MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEK VNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISD VITSSFKSNNSVVPMANPVIGSFSGYANEETEVSKIQIGNPQGDKKAGAY QTTLTFTAAFK ORF3327 (SEQ ID NO:276) MKKFSMRVVLIISVLFIAFGSANVSIAQEMDTTNKLPEEELGSLDTSNLI AEEVAQDKPAEVDNLEEIPTTDELNQNPEVLEQPVVDSDDPDLTVVSSGD FWTLYYNSANDEYSMRNFGNVPSSKPTAWNSYLKYIKHIEIEEATLTGSF ASYFDNSAFPALESVRIEQCNLSGVTSFRTAFNNHLTLEKVIIKDNDYPT TSSLLTTEYMFSHAIKLTELDVSGLDTSAVTNMKNNFGGCNSLEELDLSN FDTSSVTNNSGMFGYCESLEKLNVSHLDTSSVTDMNAMFYGCTSLEALDV SNFDTSSVTDMRANFADNEKLEKLDLSTFDTSSVTNMGTMFKDCTALKSL YLDNFTDAAIMTDMFKGTTSLTYLFVSENLSTFTSLENTSWYDEKNWVQF SNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQSKISG EYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWVENYTV VIPASISLNEATELKVEGINRGDKNLSVGLNRTATSVSESNKLTLANTAD TTIQCLAPLSWDGSENNPKNAILTLAPGSEITEGEAVLAIEAPENIQAGT YTGNLVFSINYE ORF3361 (SEQ ID NO:277) MKELRLFLDYKCYPVWVYNDAGILKENDLPDELKQDEYDKLFIDTEIEFR YEAFKDEKEKEEFFHEFIEVQKHLKETLGKEYNIVNKILV ORF3362 (SEQ ID NO:278) MKKIMKKDDYSKMPWVSAEDLYLLFEQALKDFKQSKLSKKEFFDILDELT MRQVDTYEILKEPLRGQLDNELYNLWNTENYDDVDIITSLLINLGLKNTY NKMKKSIEDTSEISPEILEEIQDAIEEVGDNIDDPYQDYMKKM ORF3365 (SEQ ID NO:279) LFNEKVKEMIRELDKYKLQDKWVRFEKLSKNKKIDSETFQDEFIIITNGI LHVENKKFQILHFFSNGDIINQQVAKISGENELRLVCDTDVSLIFIDREY FLNYATNKPSYMEWLLEETLINNKNLYNELIKYDLSAEERIVYALQYLCD KLEIESENGYQQIPKYINKIKMAKYGKISRKQLNEKIILLLDKEVLKEKK GRFYIKKSA ORF3378 (SEQ ID NO:280) VLNKKRVIVGVLLLLLSLISISYYSETFKLTLSWLLFAVVLTVLYFRQEK NFQFQWSTLITSLIISLFWMASSFNGGPYGGNFVFNSIILAGTFLVITIF VLLLLLEMRTEYKARPNRKVKWPFFALFTSIPFVVWMISFLAYYPAKMTF DSYYQWGMAHGIRQYSQWHPLLHTLWIETTSAIYDSPSSYIFSQIIVVSL IVGFAIYTLVKMGAHIWIGVCISIGYAIYPAAMFYSATAWKDFPFAAFIL LFTVLILKIVQSNGMWLKNWWHLIAFVLVAFVCINLRNNGMMIIIVSLLC LLIFMKNFRLIITGILVGTLGLNFLFGLVMTNGLNAQPNPLNQALAIPSQ QIGATFYNDGNFTPELKEYFTSILPEENWKKDYNPYTVDPIKHDTKYNSS VIEDDFGLYIKNWFKLLTANFGTYVGAYLDQTAVIWQFYSPENYKVFFDT SANIQDTRYDVRAFAKFFPEGLSEEEINKLGYEVYQNEYKNATGKDAVSY NEYKRRIDDSTNPLISISKAPSLKKITDSIYAKTTNEWQNYLLKGAIPLV LLIIAIAAVCLQRPKKKLLIFAPVVMALITIAIAMPATDFRYSYSFIFTV PIVFFATKLKNYKENQF ORF3379 (SEQ ID NO:281) MGILNEKVAVLLPCYNEELTIGKVIDDFKKELPNADIYVYDNNSKDKTFE IAKDHGAIVRKEMRQGKGNVVRSMFADIDADYYLMVDGDDTYPAEYCHEI LEVLRNKEANNVIGDRLSNGTYTEENKRNFHDFGNSLVRNTINRIFKSNL RDIMTGYRGFDRYFVKTMPVLSPGFEIETEMSIHALENRFLVKEIEIDYR DRPEGSESKLNTFSDGFKVIMTIVRLFKNSRPFLFFNLLASLFVLVGVLV GLPVIIQFAQIGLVLKFPSALLATGLIIMGMLFFICGLILDTIAHRSRQS YFLELVKYRERNPLN ORF3386 (SEQ ID NO:282) MKKLLLSISIIVGLSLLASCGLEKEYKPDIKVNEKNVSLKVWVDLNQGDF YRKVVEDFKKEHPDKDYDITVIESESGRAQEYVQKDPEAAADVFITPNDR LGQLVESGAVYQLTKYTDDIKKNNTPTSIQAATYQDKMYGFPVTAEAMFM YYDKRVFSEDDIKTFSGITSKGKLGINIAEAGADYRETPWFIANGTYLYG ENGEDPYGTTFNTPEGVQVLNWIGELKNNPNIVAVNADEISALRSGKINA VFSGVWNKDAIREVLGENMGVAVYPKADFGSGQVDMMAFQGSGIYCVNAF TKSPLDAMELADYITNADVQEKAFKELGKIPSNLEARTSSTVEKDDVAKA VIDMTSGKHSVLMPKIPEMNVFWQHMNPLLVDTYKGKIKKEDYPEALDKL VKDITPAK ORF3401 (SEQ ID NO:283) VKNRLAYIFNAFFILIFGYLLCISIFKPLEISFNHPSIFILFSAAALLVL IGFYQFSTRLNTKGDGVITIFLVSLIILTQIYLLFSLQMNSYADAFLIKG EALNMLSNGGHATTQNYFLMYPNNIFITIIRYWLYSVGGTLGITNTYLLE SAFLFVCMNITIFVLYWIVRKENGNKFGNIYLLIVLFCVPLFGYIWYFYT DTLVLPFTALIALFYYLYTKSSKWWYFIIIGLLFAVGYQIKPNIIILLPA MLIHLCFIRNWRKILLNTVIVAICFFGLSTVFTPIAESYDFKKDPTIEFP QTHWIMMGLGDPAGRYNSNDVAYTSQFKTKEEKEEANIEKIKERIEEHGP LGLIKLFDNKVLNTWTDGTPAYTWYVNAALDYPAPYDYFFGDKRVVTELP AQLFHIINLFLICLGALRFYKKREFDMSFFVNISLVGVWLFHLFWEANQR YIMFITPLMILSSIYGFKFIVESLYTKKFDLKKGLRKGFLIASFCVFLLS TVAFAFIGNSVAGESQDINKYLVKQSYAHIDLPVTSKQIVKQTFNVDSPF NSIQIAVLKEPDEASKYRLKVVDKTNKKDIYDEVIAGSDFVEATNYQINV NEKPKGKTEYVIEVYQVENKNPEKPLVLGTYTPDAVDLYPYGALYVNGVK KEKQDMGFTVSHVASEPIIPKYVSAIFDLGVIIIFAGTYYVFRRKTGDNR ORF3402 (SEQ ID NO:284) MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTAS QQAFIDKIAPAAQASQEKYHLLSSITLAQAILESGWGKSGLATQGYNLFG IKGKYNGQSVIMTTSEYVNGEWIKIDAEFRKYPSWNESVTDHTLLLVNGT SWNKDLYKKVVDATDYKVAAMELQKAGYATSPTYGASLIQVIENYDLAKY DVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSVSPASTYANKD IDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKI TSPVSNGIWSKPYNVYGREFVTNATTYAQQEIKLLREAQTAKGTYYQFSI NNKTIGWIDKRALTIYFYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEG TTSVAQATKYANKDVKISQQIETQHGTYYNISIDGKAIGWLDRNAITLYD QEEYNKTVAIDAVVKNVKGNAVWTEPYRTVGTKLIGPAETYLNKEVEVVR EAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTG NAVWTAPYKSKGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVI GWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKSKGVKLVTSA ATYKDKATKITREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKA INNTGLLSNAPGNGIWTEPYRVIGTKNVGQATAYANKTVQLIREAKTTHA TYYQMSVNGKIVGWVDKRAFTNVK ORF3410 (SEQ ID NO:285) MNKKRIIILAVLVVLLIGGVVIGVYASGNSAKDNNESKTTAKKATSTPKK AIDTEKKETTTKEATTKDSVTDDKGVVTKGSSDVEKNAPAKNNSSATDKS NSPTTPAFSLSSTGFKTSNVSSVLGGTVTTTYLSSAPSFEKIFENLTIEV NQYKVEHVVGANKAVSASNPESYLANKNGYVITLDISIKNTSAKDKMYKA DQITLIGANEFVGGSLDNFVPSNFHLIGSKADPNIFTAGKTARGLLTFTM TEAVYNDLAADSKIGVPNPDKFDASVSEANAGDDVVASFPVK ORF3457 (SEQ ID NO:286) VSTTKNNIDYIKTVQNIKSFFDEFQYLVFLLGSKNKIKLNTDGLIEIKVL TGNKISLTPIGHLVQFYLGILNDMKALHRFILIKCYIEINKKIF ORF3501 (SEQ ID NO:287) MPDWDFNNPESMKAWDLASGSYAEQVSGEVRAVVGSDLRKGNIWENVELP RLKNNPNVTKITTIDPKTGLEKIIFERK ORF3593 (SEQ ID NO:288) MKLIMNADDFGFTRAINYGIFDARNLGVLTSTTLMVTMPAFEHAVDLSKQ TPTLGIGLHLNLTLGKPLTNGASLVNQAGELIKPKFITPEYPYNEEEVYQ EFKAQYHRFVTFMKKKPSHLDSHLFSTDIYPVAASAAKRLAEEVEIPLRN HDTVGFQHVEFIWEKPLEIPYGAYENLDYIYDYAESILCYDYVEIMTHPG YLDTFILENSTFSTPRANELESLISPRMRQFLNENNVELISYHDIPKK ORF3594 (SEQ ID NO:289) MEGTELQSFKIISSAGDASSSFLKAIRHAEKSEFAEAEACIEQANQSLRE AHHVQTSLIQEEAGGDSKEVSLLLIHAQDHLMNAFVYCDLVKSVLNLYKR LDEK ORF3745 (SEQ ID NO:290) MKAKKRKEQTFHEYFKEWVDLYKVGAIRSITLQKYYVTEQKIQELVPELK IKDLDRYTYQQLLNNYALTHEKQTTMDFHHHLKGAILDAVDEGVLNQNPT RKIVIKGKNPRPKKAKFLNQFEVQVLLKELNLKEDINWDWFILLIIKTGL RFSEALALTPSDFDFSTQKISINKTWDYKMVTGSFQPTKNESSNRKIQID WQLAMQFSQLIKMKDSDKPIFVKSRVFNSTINNRLKVLCQNANIPTITIH SLRHTHASLLLFAGVSIASVANRLGHSSMTTTQETYLHIIQELENQDNDK IIRHLSMLM ORF3792 (SEQ ID NO:291) METINHFFEWAKNNNWQVDLSAVEKNLPEQILKRYGKLPDAYKAFYRQLN LCSNAGDTCWFLSEEDFLENEVDAFSWNSFEQMSLEAAEGDTNLENEVKL FWNAHLPIMMSVGGCYEYYAITLNDGNIVHGSEPEFEESSIVAESFADFL LKIVAGEIVIS ORF3793 (SEQ ID NO:292) MKVIHFYSENADYGCFSNFSLHPIVIDGVTYPTTEHYFQAQKFIDKKIIK KVINTKKPIDAAKLGRNRDFPLRKGWESMKDEVMLKAIRAKVAQHSEVKE MLLSTENAILVEHTENDHYWGDGGDGSGKNRLGKILMKVRDE ORF3840 (SEQ ID NO:293) MVVKQMDDWSTLIGELEHNTPEKVWIVREELNISEVFEIQKLEAHFILVL EGVLRMENEHQQILHYFRENNVIYQSPYELRVQNKLRLVAETPAHIVLLH REFFLNYATNQPAYSEKLVRAIMDNAASFMFELMKNDLKSEDRLAYSLQQ LCQSLELEVKNEFYLLPHYINKNKLALYSDISRKSLYKYLQNLERKGQIK MNGNQILVRISRFTNSENVDWL ORF3913 (SEQ ID NO:294) MLKKTKKNLNEIKTIIQQKPFDYEKAENLISELNLEEALLELENILLASI NNSDENARIFAYEYLYYFDSEAVFQAALIGTTDDDDLVQMCSIEILGNLV KVESLPYLKKALGDNNPDVRCFAAESIGFVGTDEAKAILQEQLNRETDSF AKVGIYYALYLLGREEMLPKLLSLLDDNYHLTVIRSLDVLRDVVNQTNKE NILLNIEKLLKRDIPISVKEKAEVVLQEIKGS ORF3914 (SEQ ID NO:295) MINLEWKELDQLEIEEKVQEVLDYSYNTWMSDKKNIRYFVRAFYIRWDML VDMYEVEDDETEGDKLKYMYDFGISELGNITEVDWIMGYCMLINPIYFEE NDNYLELEEKGQEMLRNVAINNPDDVFLTSFGIPEKDYLKWKIANREQLI QYGEDNFSYDSEFSRYFKHIINCRANEEVEKESFLKKIVRRWKQR ORF3921 (SEQ ID NO:296) VLPLFYVISHYSNLPFRAWEQRKLGDLVVDYVEKTSVQNQFPMLTSSQQK GIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNPNDIID RGIISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKF KNIVANFPSEGEQKKIGSFFKQLDDTIALHQRKLDTLKQMKKGLLQQMFP KSEEDVPKIRFADFDEEWYQRKLGEEFEKINERNDGSFGKTHWISVAKMY FVEPNKVLSNNIDTRTYVMRKGDIAFEGHSNTDFKFGRFVANDIGPGIVS ELFPVYRHKTNYDNNYWKNAIQLEHIMAPIYSKSITSSGNSSNKLDSKHF LNQKIYIADFEEQEKIGSIFKQLDNTIILYQNKLNKFDILKKAYLQTMFI ORF3970 (SEQ ID NO:297) IIALYSTREGFEKRYGFVDVDKDNSYKRLKKKSFYWYKKVIETNGNDLSY ORF3981 (SEQ ID NO:298) MKKVSSLLTQDQFWGIIDNSDKGSKLEELLEKLSEDELFGYDYWWNYFHK KSYNQSLWAVAYVVLGGCSDDGFDYFRYWLITRGKAVFTSAVENADTLCG EFDLLTEDEYPENEEVAYLVMDIFENKLGKDFDDAENEAESRIEFEEVSM PPIDFEWDEDDEDSIKKVCPNTFAKWWNNDKF ORF4017 (SEQ ID NO:299) MKLVQKVYYLLFRLVGFLPRKKDLVIFESFSGKQYSCNPRAIYEYMEEHN PEYELLWSVNPKFVAVFEAYGVPYVKRFSISWLFKMGLAKYWISNSRLPL ELPKPKKTIYVQTWHGTPLKKLGVDIDEVHIPGQTTEQYKADFVKEAQKW DYLISPNAYSSAIFRRAFGFTGEMIESGYPRNDILFSTDKELKIANIKKE LNIPEEKKVVLYAPTWRDNDFYEAGRYKFDLKIDIAKMQEKLGNEIVLLV RMHYLVAEHFDFTQYGDFVRDASNHEDIRDLYLVSDLLITDYSSVFFDYA NLQRPMLFYTYDLAEYRDTLRGFYFDFEKNAPGPLVETNEELMSELEKML ENPPKIEDSFLEQFCTWEDGHAAEKTVKIVFAEK ORF4018 (SEQ ID NO:300) VGILKEVAIYIYMLAVKITGCLARIFPVKQKVVLLVSFPENSTAIIKQMN EMKVTPKTVVFYDPRVDVTGFNFDFIQLKPKKIKHFISLMFHLNTAKVVI TDNYFVELAGLKERKNVTCIQIWHANGALKKFGWEDKAAQKRSARDKKRF QEVYRCFSKVLVGSDEMAAIFQRSFLLEDSHMLKLGIPRTDNFFNQQQLK ENAERTNTKLHLSNKKKLLYAPTFRDEELHSTTLHLDIAKMKQALGNEYQ LILKLHPSISNDLDEVVDDFVVYADKETPIETILPAVDILITDYSSIPFE FALLEKPMIFFTYDLEEYDKARGLSDGFLATIPGPFVHTTEELIQLIEQE AFDLEMVPAFAAKWNKYSDGHSSERFVSFLKEQLEK ORF4100 (SEQ ID NO:301) MSYLWTSIKMQFRIPVSVFFSLLFPLIMMFANVTSYGNFDIGEGYHFVDK YFLISTGMGMLPIALISFPIWLGESVQNKSYKRLEYFGLSAQKIIVSDVC SYILLTALSIFVNILFGYLVYGLHIPDWQYFIAYVLQCLYCNLVLLIFGA LLALIIKNPRILMPVGMCLLFMFYIFTGTFSSFSELPKSFQAVGNFLPMK YIMNDLFNVWTQNKLFISKFLALNTIYGIILSCALIAFLLRSRKIKIKS ORF4101 (SEQ ID NO:302) VHNNNILETKNLKVTINNKVILYLDKEVCISEKDKVAILGDNGAGKTTLV NSILGEKNSSGEITKKFKKNDCGVVFQENAYNDLMKVYELITLVLPHLKK KEPAQFLHKYELESLRKKYIKDLSGGEKQRLTLCLVLESHKKLYIFDELT SGLDYKKRLGLLALMKEKTKDATVINITHYFEEVENWATKVLILQKGILL FWGTISEFFSNFPHYSVIKVDQIELTKIDETDMTFMQSTDTGDGIAVICS DLQIQEETKKILDKKNVTYNTIKQNIYTTYLVAYLRGTSSSEQEVLI ORF4132 (SEQ ID NO:303) MKRKISSIIVVGIMFFQSLTTYPFITEAKENEQKEEINKPSKITKGLTNS LKYTKTILETGDTYDSVFPDSALAKVVAKEATGSENTTQLVTQADLNKIK SLNGYNKGISVLTGIDLLVNVTSISLNNNQVTDISPIDQLPNLVSLSVKN NQISSLILNAQNQLPKLTTIDIENNPDLNTIDIQDQPQLVDVKTSGYTGL RKLTTVIAKNNPELVNLGQYTIRNVYFSQVASLTKVELVNLPKVRKVNLE RNSINELKVTDLAIEDLPLGENELTDTVFDNIQNLPNLKTLDLSKNQLEE VVLDKTDVENLPNLMTLNIQQNLAIKLINVQDQPQLVDVKTSDYKELSAL TTVIAKNNPELVNLGYPIMQNVYFSQVASLTKVELVNLPKVRKVNLERNS INELKVTDLAIEDLPLGENELTDTVFDNIQNLPNLKTLDLSKWQLEEVVL DKTDVENLPNLMTLNIQQNLAIKLINVQDQPQLVDVKTSDYKELSALTTV IAKNNPELVNLGYPIMQNVYFSQVASLTKVELANLPKVRAVRLERNSINQ IELNNLVSVKDVNLNTNKITNDSIEKFKGMPILATLNLNKNQITNINMLD DFPEMTTLNIDLNSVSVLPSNLKTKMPKLSRISALNQTVTLDKAIVVDDS DLIINNEISNFGKLTDPSPISNFGTYANEKITWSSERIKNLTEVSFKFSE LINVTGIDGTFSGKVTQPFKKSTTPVINADSEIHYPQGTKKTEAEFLKDI QAQTTDDLSIKSDFEIMVNLKKVGKYTVILNVENMDGIKANPKEVTVYID AVQGANITVKYEDKSGNKLAENSILTGNVGEEYSSSEKEILGYTLTEIPT NAQGEFSLEEQTVTYIYSKNPVPAKDITVQYTDEDGIEIAPTETLSGNVD ENYVTTAKTFTGYELIETPSNAEGKFSENAQTVTYVYRAIKADPILAKEV TVNYQDELGAKISETEVLTGEIGETYTTVAKTIDGYTLIKSPINASGIFN ENPQTVTYVYQLQNNPITANITVKHLDENNNELAPSEVLSGIVDEAYTTN PKEIKDYSLVKVPTNASGKFTTEAQTVIYHYKKNSIQTSSYITVKYVDET GKELAISEVLNGNINDSYATTAKEIKGYTLVEKPANATGKFTDQDQTIKY VYRANTDEVNLDPDVPARNPNGDIQPMNGAQPPIEVPKSLPKTGSQPANL IFGLGVLLVFLSTQWLHRDKRKKDKFHNC ORF4133 (SEQ ID NO:304) MENYVSIVKIENNLSVCFYNSSEKVVAIAKKMNEINEEAYMHGYNWEAFF NYYLPKYAPDVLEGMGSDPEAGMYVAYYTLSPETEARAEKLVQVITNLIE NEELLYQIIENEGNNISWDN ORF4135 (SEQ ID NO:305) MTFLNTLKLNLENEKKRMLSDAFMKKQEGIIVNYIVTCSKDSAIGISKKA IDILLIINENTFPEWPNVDRWLSILPKYFTDSFSKSKILHSEDWLFEEWL YWFEPENRFWFLGELDPVDNEHLKISIVVQEHPFPVESLEVLLMKLGTSE LHEIGME ORF4188 (SEQ ID NO:306) MNKVTKIGDVAEKTGYSITTISRAINGNPNVSDKTKKKIFAANKELNYYP NNIAQQFRGQGTKMIGVVISFITNPFFAYLVDAIERYLSHRGYQVVMLQT LENPAKELQFIEMLQKKQLDGLIMANLENDTEEIKSLVESGKIVLCNRYL GNENLTIINIDETKAAYQATNYLIKCGYKRLAYCTGGIKNKNDYRFKGFM QAVTENGLSFDESLYFEKLLTIKDGEELLVNILEEKSTLPDAIFSNGDTV AAGILYAAKKYGIAVPEELGIIGFDNQPIAEVLNPALTTIEQPIKELGEY SAQVLLANLQGTSVPVAPDLETKLIIRETTK ORF4327 (SEQ ID NO:307) LNYDERVRVLIELKVDLSGKLEMMENEEELLCRQKHDFVSTWSNAKTEDA YRKLNEAVRKKIKETTEYAREIDEKITARIKRIEAAYKAEYQSNRSYTWR IAEIDPIKFKQKYNERLNQLSYLSCDGSVKTRLIKEFRQNNFLK ORF4369 (SEQ ID NO:308) MKKTRVTWAIVIAIAGLLVSVISLSVNITQNRYNVRGVDSSSQWKTGFQK NQTVCAIETKKHWTKGSVKYGVNQTSGTVKTKYSIYSKKK ORF4457 (SEQ ID NO:309) MRADLSIMWVEDTTSWYTEQKDLLNMDIESLGIDIEFTRISTIDDFYKLV RNDNTGFSKYDIFFVDYALSSDTEQKGSNIIVKLKDMGLTTDILFYSSKN IREIREIVKKDIEQFEGIYLADRDKDFRDKSFQLVEKNIKSLSSIKNIRG LLMDQTSENDFIVKSYISKEINELLPEQKEKIYKWFEKEVDKNIEEVTKT IKGYVERKPSTIEKYLKLPSYILPVKLQYNLLEEIININGVETFVDSTID YYLKKVVSNRNKLAHRKLVMCRQQQHLLQYNNINTFLNDDSNVCDNHEGD VVSIDDWIQLRVEVKEYGKLFDDLWEKIKS ORF4507 (SEQ ID NO:310) MIDYEKKGFFNIHTLVNKDNANISNSDNKHIYSQLMSGNGNSPMLGYLLN NNKQNLNDFKSIMFYNESNLASLINEAREMEELIDSSTLFLSKTNKKIKT HFSKVLEQRHSTRNFVYETMDLSTFSNIIQFSFGLSTRKLVYNDLQSTTR HYSSGGGLYPIDVFLYINNISGIAKGIYKYQPYTHSLHPLDVDKIDVESF FVGDNIDTSNNNFCVFFGYSINKNYVKYGELSLLNTFVELGGISHNFDLV CHSVHYTSCPIAGFNKSYLEKLLYLDGINDHIIFSNICGKE ORF4563 (SEQ ID NO:311) MKKKFSNPTFRIIASIVLGILIGVLICFVAIGLGYIHMNDGTLKEYSVKI FGLTIFDIKRVGSEMVGTPNNTSMMFIGVIISMIIAIVVEIIVSLKNRHR KETAK ORF4578 (SEQ ID NO:312) MKKKLVVLGLAGAIFLSGMGILNVSAANYSDTKFSFTLGKLGANDYTGSR QKQNTTSSYVKLNSIGKGTMDTWLLKSNGASVRSKYVTVRQGESKKIANY AYEDYGKCNVKLAAETSKTQFVRVTATGLWSPDSI ORF484 (SEQ ID NO:313) MKALERFLSKWLLPFAKVLESNTQMKAVRQGMMALVPITLVGAVPVLFQQ LGGIPKLPSWIAAVSNYINNITSPIYFATFGLMSVYVAVFVAYYYAKERN LWDIGAIVTALMSFVVVAVRPLESGGSDVAYLAGEGIFVALVISLLSVEI LHIFKNKLKFTINLGQGVPTPILRSFENLWPILFSVLIIAILSFGIETLS GIRVVELIQTLFSPLTSLVNTLPGIMLIIFIQQLLWWFGIHGYSVMAPVW LSVAFQNVDANAAAIAKGEPLSSMLIFTPDFMWSIVGVTGAGVTGALVVI MMFSKSKRYKTLGRLALIPTFFSINEPVMFGVPIVLNPRFFIPMMLAPQI AALIGWFSIKLGLMNPFTMVSPYVPVPIGAIVASFDWRYVIVLGLILVCS ALIYYPFFKIAEKEAILQETSGDQEASLDDFDF ORF485 (SEQ ID NO:314) MKIMLVCFGGLSTSILVKKMEEAIAASEKFKDKGITIEAWGKDEFSDHLD NVSIVLLGPQLSMAYEQVIEATKEHGLNVPVEVIDKEDYGNMNAVPILIA AFKKIKEAGTNTFKTEGN ORF577 (SEQ ID NO:315) MKIHAKAKKILVSLIAIMLFLSLIPGYAPMAEETSTGVEVPEKKAGEQAP TEVKEERTENEVVFNNHDGSFTKQIFADSINMEVDGEMKRIDANVEKEAD SDMIVPKQTPLELGFLDKMEDGAYQKLTKAGAEVTFRLKGARTGENEQAV TDQPATYKENEVTYENVFPKTDLRHLTFPQSVKEDIVLHEPNQVDTYVYQ IETKLGLELAKNGDVLFKNKSGETMYTLPKPVMTDSNVGAETGFAALSEN VSFEVKQLTKTVYELQLKVDTAWLNDVAREYPVYIDPSVRLDEVYNANIN SAKPTETNIGSKLWDSGQNAYTLKLGKWDNSTGNNAAYLKMDTSTLNKAT ISKATLKVYNIWHMSPTVKNDLWYYESNANWSPWQVTWNTAPATTRIGSV NVGRGEWANLDVTKTVQAWASGVRPNNGFRLATNIDQNYWKKLVASENNK NYPYLEVNYTYAQPEKPTVKTNSNGVGTGTGYMDLSWKAVPGATSYNIVI SNGYNYEYINTKSTATTWSTKGKKIFPTNDEIANGEFEFHHDGKGTEFAL DPRAQYENAFQAGSTFGLRNLTRYLFRVQAVFPGGESPNSDLVFAYMPIE KPQPPAAKAYSNLAHKETGYVELNWEKSPMADGYKVLVFNGKAYEEYDVG AETKWTTQNKGIWPTKEEIAEGKFALHHDGKGDELAKDPSPVYTNSGGNY KERTNYWFRIVAYQKAGNNATSIQSEPATPSLPEVVNKQLGMVDYWTSVP VRGGEVNATNGNFLFHETDFNLEGNGPSINVDRTFNSQDDATGIFGKGWT STLEEKLIEEENGNIVWVESDKKVHRFTKKGDKYVAPPGIYSEITKNADG YLKIEEDKSETRFLADGRLKSEKDTKGNELTYEYTDGKLTNMRDASGRTV TLAYEGELVKELVGPEDRKISYTYNDKQELISSSTARGKIYCYGYTDGLL TSIYDPKHTEEKPYETTFAYEEEKLTEITDPVGKKTTLSYDMEEQQTTLT NEKKKKTIYSYNDAGNPKKEIVDADGLKLTTTYTYESNNLVKEVNPKGQE ETYSYDADGNITQATDAYGTESYTYNGNNDVTSATDTEGRKTTVTYDGAD AVSETLATESQVSSVTQYDAYGNPIRGSGELSSAGNLLQNSGFEKGAGVS NWTLIQSDAKGSMTFDSTQSAPGTLGGSGSVKLTSEANSTVKGYSSVTQR VDVEPETTYTFSAWIKTSGMTNADAILIGRLQDANAKDITDAGVWQSNRA TSIKKNGGWVKRQLTFKTSKNTRQVLLYLDNEQPAPHKGKGTIWYDNVQF EKGSVASSYNPVVNSSFEEHNGTLPTGWARSGNTALTQAKVVDNESHSGD SAVYFERKATSEAYTHIVQDVPVNQKEAKALTISAISKSEDAKANGSVAT MSNDYSIWGTIYYQDGTTSSVQGQFPLGTNDWNRSAVVVKPTKPVKMIKV YTMFRNGLTGKAWFDDVRVIEGEVLTKNEYDASGNYVTASYDEEGRKISF TYDIYGNTTSETDEKGNKKTLTYDADNALIDTKLANGTSVAYKYDDNGNT TEKNVTASGKTQKNIYEYDVDNKITAFTDALNRTIKYEYDAAGNETKAIM PNGRVTESTYDSADRLDGIKWNDKLAFKFQYDPNGNQTKVTDEINSIVTD KTYDDANRITKVAERGGDVSYTYKDKPTKDNKGKTDKVGEVAINHGDYTA KTSYTYNDLDRNTRVNDGSKNAYFEFDEFGNINVYTAGNGTAANYTYDST QKVTNAAISSASGTQILDENYTYDAASNRTSIDNKQDGKTTYEYDAVNQL TKETLPDGTVKAYTYDGFGNRTQVAISGSETKTIAASYNDGNQLVSWNGE ALTYDANGNRTSDGKYTYTWDTGDRLSSITKKGESKPFTSYTYDDDNRRL SKTVDGVTTNYHYDGDSIDVLYETDGDGKVVRQYVYSDDNVRLAMKMNGK TLYYHYNAHGDVIALTDEAGKIVAEYAYDAWGNVLKNTASTEEAKANPYG YAGYTYDKEIEQYYLMARYYEPEQGVFTAYDPDPGDEDDPQTMNGYNYAN NNPVMMVDPDGNWAWLIPAAMAAGKFIYKFRKPIAKYGKKGAKWVGKTAK KGAKWVGKTAKKGAKWARSRYNSKKKEFTVTKNWKVGLPKKSQGGRIFAI INRKKGRLFALDYGKVGGNQKKYLHVHWNYKPKHYIIYPRKGRGK ORF633 (SEQ ID NO:316) MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVD QIFPDDALAFKVAQELGVSEDTVVTQEQLDTIETMVYVDFGVEDLTGMEY LHNLKFVDLSQNKISNLENLANLTELETVSLNYNQITDITPLMNSPKLYN LELGVNQISTLPSFENLTNLRILNLSSNQLKDISALKDTPQLTNLSISAN NISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFDANFNQIKDVT PLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDST NIVMKDNLGVTLHDWVWYTPGTYQNDTLTWENAGDNSAYFLNNQYPTYPS VTVTVYQTVTP ORF653 (SEQ ID NO:317) MKKFSMRVVLIISVLFIAFGSANVSIAQERDTTNKLPEEELGSLDTSNII AEEVAQEKPAEVEQLEEIPTTDELMQNPDVLEKSVADSDDPDLTVVSSGD FWTIYRNTVNNEYNLRMFGNVPSSRPTAWNSYLKSIKHIEIEEATLTGSF ASYFRGTDFPVLESVRIEQCNLSGVTSFEMAFYNSGIEKVIIRDNDYPKA PSLLTATQYMFSLCRNLSELDLSGLDTSAVTNMYANFQNCTSLEELDLSN FDTSSATNMYSMFSGCRSLEKLDVSNFDTSSVAHMQFMFEKCSILEELDL SNFDTSSVTNMSYMFQLCPALKSLYLDNFTDAAIMTGMFAGTTSLTYLFV SHNLSTFNNLENTSWYDEKNWVQFSNLSQLQTYHRQQSEPIGYRKGAFLS LTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTN KFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEASELKVQGINRGSKTL SVGLNYEETTISESNKLTLSNTADTTVRCLAPMSWDGSETNPEKAILTLA PGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYE ORF660 (SEQ ID NO:318) MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETV KIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGIN IATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIV AIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQ TKRNW ORF72 (SEQ ID NO:319) LKQCPVCENYTIEANYDICEVCYWEYDVVAQEYPDEIIGANNISLKQAKI NYAKFCAVEEKYITLVRKPRQDELLE ORF73 (SEQ ID NO:320) MEYEQMADSLAYGEEYNFYYKNEEYWLSKNREGHYLTKVSDGETQEFRTS EDLLGTARINGKLIIEIWENIQSQF ORF74 (SEQ ID NO:321) LKKLTTEQSFEYYLSSLCMLGLHTINLSDEEIEYEIFEELAIDYPAALSP YTRELLVDNDIIDRELSLLSKQLQTKLFELDGGILW ORF757 (SEQ ID NO:322) MKNTVHDSEILSYHADFENSQLIMFVKDEENRKYKVIFEGLLTFCFEHQM SNSIILDIVKGEVSSFISEKSILLSEGKNYFWPLDYESEDELLNYLNEKK LNYYELQASYGLNGWILCSHYHIEL ORF799 (SEQ ID NO:323) MRQPFQVLVIPFIKTEANYQFGVLHRTDADVWQFVAGGGEDEEAISETA KRESIEELNLDVDVKMYSLDSHASIPNFHFSFNKPYVVPEYCFAIDLTS CSYQVTLSLEHSELRWVSYESAVQLLEWDSNKTALYELNERLKNNDMKA M ORF817 (SEQ ID NO:324) MKKRLIGIITALLLVSGILLSPQMAQAETKVDYDALYQQGVSEGIINKAD VSLETWIKENESEYNQVYQDGLKDGVYDASLSYEEWIKLNNYGQPPVVDE NWEEVPQKPMLKGVYKGYNIKKGDILITNGTSSSGLLGHAAIANGNEYIL DIPGAGKTTRQVPTSKWMSDYDPEGWVKVYRLKDSSVANAAANWADKNYY STKGTSKQNIFPKYGMTGSRYSKNPTYCSKIVLQAYYFGTGNKPVVQVFP SLVTVYDLPNYFSKAYKPQQVKYFK ORF819 (SEQ ID NO:325) MIGMFHYLLPLNQIPHNFHAQPGRISQMMHQWDFFHYFNRVSHCTGQGYL FSRFCSPFCSASSRLIWEIDSPIALATRSILSRKICATTEVSSGIITLPN CFSFYQSHLRSFQ ORF949 (SEQ ID NO:326) LKKLVKSAVVFASLVFIGTSATMITEKASAASIDPVQKADGQATYIPKGV RDGTATEEHDGFEDGTNSVLQQVPLLRATTGYPDVNAYIKSNKFSTAKIE KQLKSQFPKFNYRNGYGKPEGIVIHETANNSSTITGEINYMSTNYNNAFV HAFVDKSRIIQIHPTENGVWGAGQYANARFIQVELVRSKTFDEFARSINN YAYYAAYLLDQYNLPVDSAHSDGKGTVWSHDAVTRYLGGTTHTDPVSYFN QWGYNFNSFVTLINEKYKAIQASKVTYDKIEYDKGVTAYARVKTAPGNAV WTKPYRTEGSKLVNQLSVYQGKNNRILREAKTPITTWYQFSIDGKVIGWV DTRALDTFYKQSMEQPANLTRYVASNKTGEAYYKVPVVDADVKWGTLAAY KDQKLTVDKQATVEGQLWYRVRTSTTFIGWTKASNLTATSPFDKIEYDKG VTAYARVKTAPGNAVWTKPYRTEGSKLVNQLSVYQGKNMRILREAKTVIT TWYQFSIDGKVIGWVDTRALDTFYKQSMEKDTNLTRYVIANKVNEAYYKV PVVDADVRWGTLAAYKDQKLTVDKQATVEGQLWYRVRTSTTFIGWTKASN LTTTTPYDKIEYDKGATAYARVKTAPGNAVWTKPYRTEGSKLVNQLSVYQ GKNNRILREAKTVITTWYQFSIDGKVIGWVDTRALDTFYKQSMEKDTNLT RYVIANKVNEAYYKVPVVDADVRWGTLAAYKGQKLTVDKQATVEGQLWYR IRTSSTFIGWTKASNLSATK

TABLE 5 Genes Specific for L. monocytogenes serovar 4b strain CLIP80459 Compared with L. monocytogenes EGDe Gene Gene category Forward primer Reverse primer ORF1025 6 No similarity GCGCTCGTCATGAAGATAAA GCTATGTTTCCCATTCAACC [SEQ ID NO:327] [SEQ ID NO:328] ORF 104 6 No similarity AAAAATACTTGGCGGAATCTTA CTTGCTCCGTTCTTCCAATA [SEQ ID NO:329] [SEQ ID NO:330]

ORF 105 1.2 Transport/binding proteins TGAATTAAAGCAAGGTGGGA TGGCTTGCTAACAAAATCGT and lipoproteins [SEQ ID NO:331] [SEQ ID NO:332] ORF 1063 1.8 Cell surface proteins TACCAACCTTGCCCAAATTA TAATCCACTTTTGCCACGTT [SEQ ID NO:333] [SEQ ID NO:334] ORF 1227 1.2 Transport/binding proteins TTGGAGTATGAGACGGTTTT CCTTTTTCGTTAGAAGGACTTG and lipoproteins [SEQ ID NO:335] [SEQ ID NO:336] ORF 1228 1.2 Transport/binding proteins TCCCAAAAACTAATCCGAGC TTTCACTTTCCGTCATTTCAA and lipoproteins [SEQ ID NO:337] [SEQ ID NO:338] ORF 1272 6 No similarity AAATCCAATAAAACTAGCAATAAGG GCAGTGAAAATTTGTTCAGGA [SEQ ID NO:339] [SEQ ID NO:340] ORF 1384 6 No similarity CCGGACTTTGCTTATCAATTT GTTCTTGCAATTCAGGAGGA [SEQ ID NO:341] [SEQ ID NO:342] ORF 1385 6 No similarity TTGAAGAACAGGTTTCGGAG CAATATCAAAATCTTCCGCAT [SEQ ID NO:343] [SEQ ID NO:344] ORF 1386 6 No similarity CAATAATTTTAAAGGAGCGTAAC CCGAGCAAGATTGCAAGTA [SEQ ID NO:345] [SEQ ID NO:346] ORF 1387 6 No similarity ACAATTCCTAACAAAACAGCTCA AATGCGACAAATTTCCAATC [SEQ ID NO:347] [SEQ ID NO:348] ORF 1388 6 No similarity no primer, too small no primer, too small ORF 1389 6 No similarity ATTTTAATTTGCATCGAGCG TACGCAAGTAACATAATCGCC [SEQ ID NO:349] [SEQ ID NO:350]

ORF 1390 1.2 Transport/binding proteins TGAATCAAATAACCCAAATTGA CTGGCGAATGAGTAGCAAAT and lipoproteins [SEQ ID NO:351] [SEQ ID NO:352] ORF 1391 6 No similarity GGGGGTAAACCACAAGTTTT CCACAAATCAAATCAAACACA [SEQ ID NO:353] [SEQ ID NO:354] ORF 1400 1.1 Cell wall ATCGAGAAGCGGGAATAAGT TAGAGTTTCGCACAAGGACC [SEQ ID NO:355] [SEQ ID NO:356]

ORF 1445 5.2 From other organisms TCCTGCTGGTTTTATTACGG ATCAACTACGACTGCCCAAG [SEQ ID NO:357] [SEQ ID NO:358] ORF 149 1.8 Cell surface proteins AGGACCGGGAAAATCACTAA CACCATAGCAGTGTTTGAAGG [SEQ ID NO:359] [SEQ ID NO:360]

ORF 1490 1.2 Transport/binding proteins TTGGACCAGGAGTTGTGAAC CAATGTTATCCCAGCGATTC and lipoproteins [SEQ ID NO:361] [SEQ ID NO:362]

ORF 1491 5.2 From other organisms CTTGGCGAAAACGACTTAAA CATGACAATGGCAACTTTGA [SEQ ID NO:363] [SEQ ID NO:364] ORF 1492 3.5 Regulation AACCGCAAAAGAAAGGCTAT TTTCGTCGTAGTGATGGGAT [SEQ ID NO:365] [SEQ ID NO:366] ORF 150 1.8 Cell surface proteins AAAAGGGATGATTAGTTTAATTGC GCCAACCAATAATTTTGTCTC [SEQ ID NO:367] [SEQ ID NO:368] ORF 1504 1.8 Cell surface proteins TGACTGAAGCGAATCTTGAA TGGATTTAACCAAGCATACGA [SEQ ID NO:369] [SEQ ID NO:370]

ORF 1590 1.8 Cell surface proteins CATCTGACGTTTCACAAGCA GCATAATTTCCATAGCCCCT [SEQ ID NO:371] [SEQ ID NO:372] ORF 1654 2.1.1 Specific pathways AATTTTCCGGATAACTTGCC AATTTTCCGGATAACTTGCC [SEQ ID NO:373] [SEQ ID NO:374] ORF 1655 3.5 Regulation GAGGCAGAAACTGGATTTGA AAGTTTGTTGTTCCGCATGT [SEQ ID NO:375] [SEQ ID NO:376] ORF 1680 1.2 Transport/binding proteins TTACTTGTTTCGATTGGGGA TTTAAAAAGTCGTTCTGCGG and lipoproteins [SEQ ID NO:377] [SEQ ID NO:378] ORF 1681 1.2 Transport/binding proteins GTGAATGCACCATAAAGGCT ATTCGTTCTGCTTGATTTGC and lipoproteins [SEQ ID NO:379] [SEQ ID NO:380] ORF 1683 5.2 From other organisms TGCATCGGTTGGCTATTATT TGTTTGCCTACTTCAATCCAA [SEQ ID NO:381] [SEQ ID NO:382] ORF 1684 3.5 Regulation TTAGGCGAGCGATTATCAAC GCAATCAAAATCATTGCGTT [SEQ ID NO:383] [SEQ ID NO:384] ORF 1717 1.8 Cell surface proteins TCCATGTTTGCTGCTTGTAA CAAGTGAGCTGCACTCAAAA [SEQ ID NO:385] [SEQ ID NO:386] ORF 1718 3.5 Regulation GGTAGAAATAACGGGGGATG ACTCGTTCACTGGCAAAATC [SEQ ID NO:387] [SEQ ID NO:388] ORF 1739 1.1 Cell wall TTAATGATGGAAGCACGGAT TTAATGATGGAAGCACGGAT [SEQ ID NO:389] [SEQ ID NO:390] ORF 1813 5.2 From other organisms TTCTGGTGGGTATAAAGGAAAA CATTCCTTCCAATGACCTTT [SEQ ID NO:391] [SEQ ID NO:392] ORF 1849 1.8 Cell surface proteins CTGCAATCAGCCAGATTTTT GCGCTTGTAGCTCATCTAGG [SEQ ID NO:393] [SEQ ID NO:394] ORF 1912 5.1 From Listeria ACAAATCTTTCCGGTGATGA TTAGCAGCTGCAATAGGGTC [SEQ ID NO:395] [SEQ ID NO:396] ORF 1913 5.1 From Listeria CCCGGTTAGAACAGCAACTA TCATTGGTTCCACTCCTTTC [SEQ ID NO:397] [SEQ ID NO:398] ORF 1998 3.2 DNA restriction/modification AAGCGTACCAGTAATCCGGT GAGCATTAATTCCTGGTTGG and repair [SEQ ID NO:399] [SEQ ID NO:400] ORF 1999 3.2 DNA restriction/modification GGGAAAATTGGGAGAGTGTT CGCGTCTACCTGAGTTCTTC and repair [SEQ ID NO:401] [SEQ ID NO:402] ORF 2013 1.8 Cell surface proteins GCAGGCGAAACATATGAAAC CTATCGCGCAACGATCTAAT [SEQ ID NO:403] [SEQ ID NO:404]

ORF 2017 1.8 Cell surface proteins (2 AACGGTTTTTCAAGCATTTG CAGAGTCCACACCTGTTGGT sondes) [SEQ ID NO:405] [SEQ ID NO:406] ORF 2019 1.8 Cell surface proteins GATTATCCGACAGCACCATC CAACAAACATGGCCAACATA [SEQ ID NO:407] [SEQ ID NO:408]

ORF 2074 1.1 Transport/binding proteins TTCTCTCTGGAATGAGTCCG TGAGAAGACGGCACCTGTAT and lipoproteins [SEQ ID NO:409] [SEQ ID NO:410] ORF 2075 1.1 Transport/binding proteins TTGACAGCTTTTAGAGCGGA ATACTTAATTTCGTCGCCCC and lipoproteins [SEQ ID NO:411] [SEQ ID NO:412]

ORF 2076 1.1 Transport/binding proteins CAAGGTATGGCGACATTAGG TAAAAGCGCCCAAATAAGTG and lipoproteins [SEQ ID NO:413] [SEQ ID NO:414]

ORF 2110 5.2 From other organisms TTAGGTGGAGGAATTGTTGC TTCGTGCCATTATATCCAGG [SEQ ID NO:415] [SEQ ID NO:416] ORF 2192 3.2 DNA restriction/modification GCAGAAGCAAAATTTGAAGC TCCGTCACCATGATAACCTT and repair [SEQ ID NO:417] [SEQ ID NO:418] ORF 2217 3.2 DNA CGATGAAAAATGATGAAGGG ATCTGAAAGAAGATGGCGTG restriction/modification and [SEQ ID NO:419] [SEQ ID NO:420] repair ORF 2247 5.1 From Listeria CATCCGCTTATGTGGCTAGT CGTTTCACATGGTAGGTCGT [SEQ ID NO:421] [SEQ ID NO:422] ORF 2291 1.8 Cell surface proteins no primer no primer ORF 2293 6 No similarity no primer no primer ORF 2336 5.1 From Listeria no primer no primer

ORF 2372 1.1 Cell wall CGAGGACAGATTTGAAAGGA GCAAAATTGCTTTCTGTGGT [SEQ ID NO:423] [SEQ ID NO:424] ORF 2375 1.8 Cell surface proteins no primer no primer ORF 2440 5.2 From other organisms CCACATCCAATTGCATAACA CCAATTACGGTGGTTCTCAT [SEQ ID NO:425] [SEQ ID NO:426] ORF 2462 1.1 Cell wall TGTCGTGTCTATTGATGCTGA GCCAATTAACCACAAGGAAA [SEQ ID NO:427] [SEQ ID NO:428]

ORF 2541 1.8 Cell surface proteins TAACAACCATTGTCCCTTGG AACCAATCAGCAGGAATGTC [SEQ ID NO:429] [SEQ ID NO:430] ORF 2568 1.8 Cell surface proteins CTTTAGTTTTCCAGGCACCA CACCCGTTTTCACTGTATCC [SEQ ID NO:431] [SEQ ID NO:432] ORF 2646 5.1 From Listeria ACGGTCTTTCATCTAACCCC TTTGTTGGGTAGCCATTGAT [SEQ ID NO:433] [SEQ ID NO:434] ORF 2666 6 No similarity AAATGCACTGCACCAATCTT AAATACTCCAACGGGTCCTC [SEQ ID NO:435] [SEQ ID NO:436] ORF 2758 6 No similarity AATGCCAAAAGAATCGAAAC AAGCGGATTTCATATTGCTG [SEQ ID NO:437] [SEQ ID NO:438]

ORF 2759 2.1.1 Specific pathways CATTTCTCGCGAATCACTCT TAGCTAAACGTTCCACTCGG [SEQ ID NO:439] [SEQ ID NO:440] ORF 2763 1.1 Cell wall CAGGCGGTAATAATAAGCGA GCCAGTCATCTGCCATATTT [SEQ ID NO:441] [SEQ ID NO:442]

ORF 2777 5.2 From other organisms GCCGAGGTCATATCACTCAA TGGAAGTATCATCAGAAACCAA [SEQ ID NO:443] [SEQ ID NO:444] ORF 2778 1.2 Transport/binding proteins TTGGTTCACACAAAACATGG AAAAATGAGTAGCAGTGAGCA and lipoproteins [SEQ ID NO:445] [SEQ ID NO:446] ORF 2779 1.2 Transport/binding proteins TTTTACTTCTTGCTACTTGTTCTCT CAAGTATAGGATAAATGCTACCGC and lipoproteins [SEQ ID NO:447] [SEQ ID NO:448] ORF 2780 5.2 From other organisms TTTGACTCCCGTTCAAAAC TCCAGTTCTAAAGCCCATACC [SEQ ID NO:449] [SEQ ID NO:450] ORF 2815 5.2 From other organisms AAGCGTGATGAAGAATTGGA ATCCGCTAGGGAAGCTTTAT [SEQ ID NO:451] [SEQ ID NO:452] ORF 2817 6 No similarity CTGTTTCCATTGGTATCGCT GCTCCATTGGCTCTTAAGGT [SEQ ID NO:453] [SEQ ID NO:454]

ORF 2819 5.2 From other organisms TTTCAAGGAGGAGCAAAATG CACTAAAGCCTCCCATTGAG [SEQ ID NO:455] [SEQ ID NO:456] ORF 2836 1.8 Cell surface proteins TGGTGAAATGGAGAGGTTTT TTTCCAGTTCCATTTTCCAC [SEQ ID NO:457] [SEQ ID NO:458]

ORF 2847 6 No similarity ACAACCGGCCAATTAAGACT TGCAAATACTGCGCTGATAG [SEQ ID NO:459] [SEQ ID NO:460] ORF 2848 6 No similarity CGAAAGGAACCACATGTATGA GCTCTTTTTGTATAGGAAATGTAAT [SEQ ID NO:461] [SEQ ID NO:462] ORF 2854 5.1 From Listeria AATCACAGATGGGCCAATTA ATATAGGAGCGCAGAGTTGC [SEQ ID NO:463] [SEQ ID NO:464] ORF 2884 6 No similarity no primer no primer ORF 2885 6 No similarity no primer no primer ORF 2886 6 No similarity TTGAAATTGCTGCTGATTATGT ATCTTGTTCTACACTGCCGC [SEQ ID NO:465] [SEQ ID NO:466] ORF 2887 6 No similarity ATGCTTGACAAACAACAACTAT GCGCCAAATCTATTCCTTTT [SEQ ID NO:467] [SEQ ID NO:468] ORF 29 1.8 Cell surface proteins TAACTATTGGCGATGGTGCT AATCGATTTGTCCCAGTGAA [SEQ ID NO:469] [SEQ ID NO:470] ORF 2925 5.1 From Listeria AAAACAAGGCGTTATGTGGA CCCAATCCCACTCATGTCTA [SEQ ID NO:471] [SEQ ID NO:472] ORF 2927 5.2 From other organisms no primer no primer ORF 2969 6 No similarity ATCCAATTCGAAAGGGACTC TGTTTGATTAATTCTGTGGCA [SEQ ID NO:473] [SEQ ID NO:474] ORF 2970 6 No similarity GGATGTGAAAATGGGGATAC CTATTGGCACTCCCGTATTG [SEQ ID NO:475] [SEQ ID NO:476] ORF 3102 6 No similarity AGATGTCGTTGAACAGAGGG TTGGTTGGAGTGTCCAATTT [SEQ ID NO:477] [SEQ ID NO:478]

ORF 3103 6 No similarity TGGCAAAAGAAATTAAGGTAAA GTTTGTCCCAACTGACCATC [SEQ ID NO:479] [SEQ ID NO:480] ORF 3132 6 No similarity ACCGATTATTTGCAACCTCT TGACGTTCTTTTTATCGTAAAGC [SEQ ID NO:481] [SEQ ID NO:482] ORF 3135 6 No similarity TACTTTACAATTCACAATGGGATTA ACAACAAATATTGGAATTCTGAAAC [SEQ ID NO:483] [SEQ ID NO:484] ORF 3136 6 No similarity TCCAGTGATGGAAATGTGATT ACCTCTGTTTTAATGACGCCT [SEQ ID NO:485] [SEQ ID NO:486] ORF 3137 6 No similarity GGAGACGCTGAAAAGACAGA TTTTTCGGGTTCTCTTCTGA [SEQ ID NO:487] [SEQ ID NO:488] ORF 3138 6 No similarity TCCAATGCCAGATAAAACAGTA TCAATTTCTTCCACACTTTTACA [SEQ ID NO:489] [SEQ ID NO:490] ORF 3140 5.2 From other organisms GGCACTAGTTATTGGAGTATTGG ACCAAGTTTCCTCATCCCA [SEQ ID NO:491] [SEQ ID NO:492] ORF 3141 1.2 Transport/binding proteins TACTTAGATCGCTTGCTGGC AATTTTCCCTTGGTCCATTC and lipoproteins [SEQ ID NO:493] [SEQ ID NO:494] ORF 3142 5 From other organsisms TCCTCGTTCCTAAAGGTATTCA TATATGCCGGTTTGGTTTCA [SEQ ID NO:495] [SEQ ID NO:496] ORF 3144 6 No similarity TGTCTAACAAAGCGGAAGATG TGTAGTTATTGTCGCAGGGA [SEQ ID NO:497] [SEQ ID NO:498] ORF 3172 5.2 From other organsims TGATGTTAGAGGCGAGTTTGA TAATTCCTCTGCAGTTGGCT [SEQ ID NO:499] [SEQ ID NO:500] ORF 3173 6 No similarity AGTCAAAATCACAAGCGAGC CTTCTGCTTGAGCACTCCAT [SEQ ID NO:501] [SEQ ID NO:502] ORF 3174 6 No similarity TGGCTTATTGATTCACTGGC TTTGCCGTATATCGAGGAGT [SEQ ID NO:503] [SEQ ID NO:504] ORF 3175 6 No similarity no primer no primer ORF 3183 6 No similarity CAGCAGGCCTTTATGGTAGA CTTTCCTCTCCCAACAACACT [SEQ ID NO:505] [SEQ ID NO:506]

ORF 3184 5.2 From other organisms TGGGAAACTTTGAGTGGAAA TTGCAAAGGCATCCATACTT [SEQ ID NO:507] [SEQ ID NO:508] ORF 3185 6 No similarity CGCAGACATTTGACAATGAT CCAGTTTCGCCATGTTCTAT [SEQ ID NO:509] [SEQ ID NO:510] ORF 3222 6 No similarity no primer no primer ORF 3224 1.8 Cell surface proteins GATTTGCCTTTATCCCTGGT TGGTTACGTGGATGTCCTTT [SEQ ID NO:511] [SEQ ID NO:512] ORF 3277 6 No similarity GCTTGGAATGCTTTTGATA TTGAAGCATGATAAGTGCCA [SEQ ID NO:513] [SEQ ID NO:514] ORF 3278 6 No similarity TTTTGAGCCCGTTCTGTTTA CAATAATCCCACCAACCAAG [SEQ ID NO:515] [SEQ ID NO:516] ORF 3279 1.2 Transport/binding proteins CAACAAATAACTGTCGCACG CCAATCAAAGCAAACAATCC and lipoproteins [SEQ ID NO:517] [SEQ ID NO:518] ORF 3283 6 No similarity no primer no primer ORF 3291 5.2 From other organsims ACCTATTGGAAGCGTTGTTT ATCTCATCCTCCTCTTCTGGA [SEQ ID NO:519] [SEQ ID NO:520] ORF 3316 5.2 From other organsisms GCAAAAATAATTTCAGAAAATCC TTCCAAATACCAAAAATCAGAAA [SEQ ID NO:521] [SEQ ID NO:522] ORF 3324 4.5 Transposon and IS no primer no primer ORF 3325 6 No similarity no primer no primer ORF 3326 6 No similarity no primer no primer ORF 3327 1.8 Cell surface proteins CGTCTTTTAGAACCGCATTT TCATAATTGCTGCATCCGTA [SEQ ID NO:523] [SEQ ID NO:524] ORF 3361 6 No similarity TTCAATCAAATAAAGGAGCGTAT CGATATTGTATTCCTTACCTAATGT [SEQ ID NO:525] [SEQ ID NO:526] ORF 3362 6 No similarity GATTATTCTAAAATGCCATGGGTA ATGGATCATCTATATTATCTCCGA [SEQ ID NO:527] [SEQ ID NO:528] ORF 3365 3.5 Regulation GAAAAAGTAAAAGAAATGATCCGA TTTGTTGGTAGCCATTTTCA [SEQ ID NO:529] [SEQ ID NO:530] ORF 3378 1.1 Cell wall AGGGAGTGGAGAAAAAGAGTG AGGTGAGTCGTAAATCGCAC [SEQ ID NO:531] [SEQ ID NO:532] ORF 3379 1.1 Cell wall CGCGGATATAGATGCTGATT ACAAGCACAAACAAAGAGGC [SEQ ID NO:533] [SEQ ID NO:534] ORF 3386 1.2 Transport/binding proteins ATCTGAATCTGGACGAGCAC CCGGATCTAAGGGCACTAAT and lipoproteins [SEQ ID NO:535] [SEQ ID NO:536]

ORF 3401 5.1 From Listeria TGCATAAGCATTTTTAAACCG CCAAATAATGGCACACAGAA [SEQ ID NO:537] [SEQ ID NO:538] ORF 3402 1.1 Cell wall GCAGCAACCTATAAAGGCAA GTCTTAGCCTCGCGTATCAA [SEQ ID NO:539] [SEQ ID NO:540] ORF 3410 5.2 From other organsisms ACAACCAAAGAAGCGACAAC GTAAGAAGCCCACGAGCTG [SEQ ID NO:541] [SEQ ID NO:542] ORF 3457 4.6 Miscellaneous GTGTCAACGACGAAAAACAA CGATGTAGTGCTTTCATGTCA [SEQ ID NO:543] [SEQ ID NO:544] ORF 3501 6 No similarity AATCCTGAGTCAATGAAAGCA AGTCCTGTTTTAGGATCAATCG [SEQ ID NO:545] [SEQ ID NO:546] ORF 3593 5.2 From other organisms GCAGATGATTTTGGGTTCAC AAACTCGACATGCTGAAAGC [SEQ ID NO:547] [SEQ ID NO:548] ORF 3594 1.2 Transport/binding proteins GATGCCTCTTCCTCGTTTCT ACTTTTCATCCAAACGCTTA and lipoproteins [SEQ ID NO:549] [SEQ ID NO:550] ORF 3745 4.3 Phage related functions GCGCTATTTTAGATGCGGTA AAGATGCATGGGTATGTCGT [SEQ ID NO:551] [SEQ ID NO:552]

ORF 3792 6 No similarity GGGCTAAAAATAATAATTGGCA CACTATTTCTCCAGCCACGA [SEQ ID NO:553] [SEQ ID NO:554] ORF 3793 5.2 From other organisms AGTGAAAATGCGGACTATGG CTGACTTTCATTAAAATCTTGCC [SEQ ID NO:555] [SEQ ID NO:556]

ORF 3840 5.1 From Listeria GAAACAAATGGACGACTGGT TGGCATAGCTGCTGTAATGA [SEQ ID NO:557] [SEQ ID NO:558] ORF 3913 5.2 From other organisms TGAGAAGGCAGAAAATTTGA TCCAAGCTTCTAATCACCGT [SEQ ID NO:559] [SEQ ID NO:560] ORF 3914 6 No similarity TTATTTTGTACGGGCGTTTT ACCTGCGCACAATCTTCTT [SEQ ID NO:561] [SEQ ID NO:562] ORF 3921 3.2 DNA restriction/modification TGCAAATCGACAAGTAACCA GAACCGTCATTACGCTCATT and repair [SEQ ID NO:563] [SEQ ID NO:564] ORF 3970 5.2 From other organisms no primer no primer ORF 3981 6 No similarity CAAAGGCAGCAAATTAGAAGA GCAAAAGTGTTTGGGCATA [SEQ ID NO:565] [SEQ ID NO:566] ORF 4017 1.1 Cell Wall GGCTGTTTTTGAAGCTTACG GTGAAATCAAAATGTTCCGC [SEQ ID NO:567] [SEQ ID NO:568] ORF 4018 1.1 Cell wall AGTGGATGTGACCGGTTTTA CCGAGTGCTTGTTTCATCTT [SEQ ID NO:569] [SEQ ID NO:570] ORF 4100 1.2 Transport/binding proteins AATCTGGCTTGGTGAAAGTG GTGCGCAGGATAAGATGATT and lipoproteins [SEQ ID NO:571] [SEQ ID NO:572] ORF 4101 1.2 Transport/binding proteins CTAGGAGACAATGGAGCTGG AACTTTCGTTGCCCAGTTTT and lipoproteins [SEQ ID NO:573] [SEQ ID NO:574] ORF 4132 1.8 Cell surface proteins GTCGGGATAATGTTCTTTCAA CAATGGTTGTTAGTTTCGGG [SEQ ID NO:575] [SEQ ID NO:576] ORF 4133 4.3 Phage related functions GTGCTTTTACAACAGCTCGG CTAATATTATTGCCTTCATTTTCA [SEQ ID NO:577] [SEQ ID NO:578] ORF 4135 4.3 Phage related functions AAAGAGAATGTTATCCGATGCT TCATTCCATACCAATTTCATGT [SEQ ID NO:579] [SEQ ID NO:580] ORF 4188 3.5 Regulation AGCAGAGAAAACGGGCTATT CAGTACAGTAGGCAAGGCGT [SEQ ID NO:581] [SEQ ID NO:582] ORF 4327 6 No similarity TGAATTATGATGAACGTGTACGA TAAACGTGTTTTTACGCTGC [SEQ ID NO:583] [SEQ ID NO:584] ORF 4369 6 No similarity GAGAGCGAACTAGAGGGAGG CCAGAAGTTTGGTTCACACC [SEQ ID NO:585] [SEQ ID NO:586] ORF 4457 6 No similarity AGGGATAAAGATTTCAGGGAT TGTTGTTGCTGCCTACACAT [SEQ ID NO:587] [SEQ ID NO:588] ORF 4507 5.2 From other organisms AGGAAACAGCAAAATGATCG ATGCAAGCTATGCGTGTATG [SEQ ID NO:589] [SEQ ID NO:590] ORF 4563 1.2 Transport/binding proteins ATACACATGAATGATGGCACA TCATTTTGCTGTTTCCTTTCT and lipoproteins [SEQ ID NO:591] [SEQ ID NO:592] ORF 4578 6 No similarity GCGGGTGCAATATTTTATC CCAAAGGCCTGTAGCAGTAA [SEQ ID NO:593] [SEQ ID NO:594] ORF 484 1.2 Transport/binding proteins AGGCAGTACGTCAAGGAATG AAAGAACGTAAAATCGGCGT and lipoproteins [SEQ ID NO:595] [SEQ ID NO:596] ORF 485 1.2 Transport/binding proteins TTTGGCGGATTATCCACTT TTTCCCTCCGTCTTAAATGT and lipoproteins [SEQ ID NO:597] [SEQ ID NO:598] ORF 577 1.8 Cell surface proteins TTTTAATAACCACGACGGGA AACATTCTCGGATAACGCTG [SEQ ID NO:599] [SEQ ID NO:600] ORF 633 1.9 Soluble Internalins AGTCGCACAGGAACTAGGTG GATTGCTTTCGGCATAAAAA [SEQ ID NO:601] [SEQ ID NO:602] ORF 653 1.8 Cell surface proteins TTGATTTGAGTGGCCTTGAT ACTGCACCCAATTCTTTTCA [SEQ ID NO:603] [SEQ ID NO:604] ORF 660 6 No similarity ATGAATGACGAAGAAAACGG CCACATTCGTTTAGTCTGGG [SEQ ID NO:605] [SEQ ID NO:606]

ORF 72 5.2 From other organisms GGGTTTTTCACAACAAGTGG [SEQ ID NO:607] ORF 73 6 No similarity TCCCTCTATCCGTTCAATCA [SEQ ID NO:608] ORF 74 6 No similarity TTCGCTATGTATGTTAGGATTGC CCACAGAATTCCTCCATCAA [SEQ ID NO:609] [SEQ ID NO:610]

ORF 757 6 No similarity AGCGAAATATTGTCTTATCATGC AGTGAGAACATAATATCCAACCGT [SEQ ID NO:611] [SEQ ID NO:612]

ORF 799 6 No similarity CGTTTATTAAAACGGAAGCA TTGTTTTTCAACCGTTCATTT [SEQ ID NO:613] [SEQ ID NO:614]

ORF 817 5.2 From other organsims TGACGCATTGTATCAACAGG TTTTGTTTGGATGTGCCTTT [SEQ ID NO:615] [SEQ ID NO:616] ORF 819 6 No similarity TGATTGGAATGTTCCACTATT AAATGAAAAACAGTTCGGTAGTG [SEQ ID NO:617] [SEQ ID NO:618] ORF 949 1.8 Cell surface proteins GTCGAAGGACAGCTTTGGTA CAGCTAAAGTGCCCCATCTA [SEQ ID NO:619] [SEQ ID NO:620] Gene names in bold type were used to construct the macroarray described in Example 1. Gene names flanked by a bar were used to generate a second array comprising 192 genes.

TABLE 6 L. monocytogenes (CLIP 80459) specific genes Gene Description Functional category ORF 2541 unknwon, similar to internalin proteins, putative peptidoglycan bound cell surface proteins protein (LPXTG motif) ORF 2017 unknwon, similar to internalin proteins, putative peptidoglycan bound cell surface proteins protein (LPXTG motif) ORF 3401 unknown unknown ORF 2074 unknown similar to oligo-1,6-glucosidase Specific pathways ORF 0528-0529 unknown—unknown unknown ORF 2815 unknown, similar to heat shock protein HtpG unknown ORF 2568-2569 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif)-unknown ORF 2847 similar to phage integrase Phage-related functions ORF1388-1387 unknown—unknown unknown ORF 0799 unknown unknown ORF 72-73-74 unknown—unknown—unknown unknown ORF1912-1913 unknown—unknown unknown ORF 0150 unknown, similar to amidase cell wall ORF 2777 unknown unknown ORF 2579 unknown, sucrose phosphorylase Specific pathways ORF 0075 unknown unknown ORF 660 unknown unknown ORF 2884-2885 unknown unknown ORF 2885 unknown unknown ORF 1445 unknown, conserved hypothetical protein ykcB - Bacillus subtilis unknown ORF 1590 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif) ORF 0182 unknown, similar to B. subtilis YukA, unknown ORF 1761 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif) ORF 0105 unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 2372 unknown, similar to teichoic acid biosynthesis protein C cell wall ORF 2110 unknown, similar to hypothetical protein unknown ORF 1491 unknown, similar to hypothetical protein unknown ORF 1490 unknown, similar to sucrose-specific PTS system IIBC component Transport/binding proteins and lipoproteins ORF 1390 unknown, similar to hypothetical protein unknown ORF 1391 unknown unknown ORF 1228 unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 0029 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif) ORF 3792 unknown unknown ORF 3840 unknown, similar to transcription regulator Regulation ORF 4101 unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 3103 unknown, similar to peptidoglycan lytic protein P45 cell wall ORF 1490 unknown, similar to sucrose phosphotransferase enzyme IIBC Transport/binding proteins and component lipoproteins ORF 2217 unknown, imilar to type II DNA modification enzyme DNA restriction/modification and repair ORF 2939-2968 unknown—unknown unknown ORF 4457 unknown, DNA double-strand break repair rad50 ATPase DNA restriction/modification and repair ORF 3184 unknown unknown ORF 0148-0149 unknown-unknown, similar to amidase cell wall ORF 3157 unknown, similar to phage protein Phage-related functions ORF 2858 unknown, similar to hypothetical protein unknown ORF 1384-1385 unknown—unknown unknown ORF 2541 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif) ORF 2819 unknown, similar to transcriptional regulator Regulation ORF 2262 unknown unknown ORF 0817 unknown unknown ORF 0757 unknown unknown ORF 2013 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif) ORF 2076 unknown, similar to maltodextrin ABC transporter Transport/binding proteins and lipoproteins ORF 2013 unknwon, internalin-like, putative peptidoglycan bound protein (LPXTG cell surface proteins motif)

TABLE 7 List of the Genes and Probe Primers on the Macroarray Spot Label Spot Lm 4b ORF 2541 TACAATCTCAGCCGAAAAGAA ATCGCGAAAAGTGAGGTTTTA [SEQ ID NO:621] [SEQ ID NO:622] ORF 2017 TCTTAGAAGCTGATGCAGTCG AAAAATTAGCTGTTCCGTTCG [SEQ ID NO:623] [SEQ ID NO:624] ORF 3401 GCTTTTTAATCGCGAGTTTCT CCAAATCAAAAATAGCGGAGA [SEQ ID NO:625] [SEQ ID NO:626] ORF 2074 CATCGATTTGTTCCTGCTCTA GGATGTGCCTGAAGAAAGACT [SEQ ID NO:627] [SEQ ID NO:628] ORF528-529 GTGCTGGAAAGATAATGCTGA AAAAATACCCATTCCAACAGC [SEQ ID NO:629] [SEQ ID NO:630] ORF 2815 GGATAGGGAAATTAGCAGCAC ATCCCTTCAACTCAAATTCGT [SEQ ID NO:631] [SEQ ID NO:632] ORF 2568-2569 GAACGGTCGGTATTTCATTCT AACCGTTTGTGCCTCTTTACT [SEQ ID NO:633] [SEQ ID NO:634] ORF 2847 TAAGTGTCGGACTTGTTGTCC AGCCTTGGCTGATTTAACACT [SEQ ID NO:635] [SEQ ID NO:636] ORF1388-1387 TATTGCCAGTACAGGCTCACT CGACAAATTTCCAATCAAATG [SEQ ID NO:637] [SEQ ID NO:638] ORF 799 AAATTCCAAAAGGACGTGAGT CATTGTTTTTCAACCGTTCAT [SEQ ID NO:639] [SEQ ID NO:640] ORF 72-73-74 TGCGTGTATTATGAATCGTCA GCGAAGTATGCTACTGGGAAT [SEQ ID NO:641] [SEQ ID NO:642] ORF1912-1913 ACCCGGTTAGAACAGCAACTA AAACTCGCGTATGTATTGTGC [SEQ ID NO:643] [SEQ ID NO:644] ORF 150 TTTTTGCATAAGAAGGTGCAG TTCAAGAATATCAAAATTCTAACCTTT [SEQ ID NO:645] [SEQ ID NO:646] ORF 2777 AAATCCAAAACCAAAATCTGC ATGGTATTTGGGATGAGGAAA [SEQ ID NO:647] [SEQ ID NO:648] ORF 2759 TGGATGAAGTGAAAGCAGAAG CACAACGCTTTAACAACTGGT [SEQ ID NO:649] [SEQ ID NO:650] ORF 75 CCAGGGGCTATAGGTATGAAA CAACAGTTTCTGGCATTCACT [SEQ ID NO:651] [SEQ ID NO:652] ORF 660 GGTTGCAGGGATACTTTTGTT TGATCGAGCAGCATCAATAAT [SEQ ID NO:653] [SEQ ID NO:654] ORF 2884 CAGCCCTCTTTTCTGTGTATG CAAAAAGATTTCGGAACACAA [SEQ ID NO:655] [SEQ ID NO:656] ORF 2885 CATAATCCCCGCAAAAAGTAT TAATGGATTTGGAATTCATCG [SEQ ID NO:657] [SEQ ID NO:658] ORF 1445 TTCATTTCGATACACCAGGAA AAAAATGCTCCAAGCTTTCAT [SEQ ID NO:659] [SEQ ID NO:660] ORF 1590 GTGCACTAGCAAATGTGACAA ACTTAATATTCGGGCTTGCAT [SEQ ID NO:661] [SEQ ID NO:662] ORF 182 CTCTCTGGAAGTTCTCCTTGC TCTTAGCCAATATCGTGTTGC [SEQ ID NO:663] [SEQ ID NO:664] ORF 2017a ACGCGAAAGATAATTTTGACC CCTTAGAGCAAATCCCCATAG [SEQ ID NO:665] [SEQ ID NO:666] ORF 104-105 AATGAGACAACGGCTTGGTAT TACACCCCATCTTCAAATTCA [SEQ ID NO:667] [SEQ ID NO:668] ORF 2372 AGATAGCCTGATGCGAGTTTT ACGTTTTAGGATCTCCACCTG [SEQ ID NO:669] [SEQ ID NO:670] ORF 2110 AGTGGACAATTGATTGGTGAA CATCCATCCCTTACTTTGGAC [SEQ ID NO:671] [SEQ ID NO:672] ORF 1491 GGTATTGCTGCAAGTGGTAGA CCAATCGAACTCGTGTCATAC [SEQ ID NO:673] [SEQ ID NO:674] ORF 1490 GGCACAAAAACTGGTAAGGAA TGATACAAGTCCTGCAAAAGG [SEQ ID NO:675] [SEQ ID NO:676] ORF 1390 ATGGAGTTGAGGAGGATGAAA GCTTTTCCCCAGAAGAAAGTT [SEQ ID NO:677] [SEQ ID NO:678] ORF 1391 GCAAGGAAAAATGAAAATGCT CGCCGGAAAGTTTAGTATGAT [SEQ ID NO:679] [SEQ ID NO:680] ORF 1228 GTAGCTTGGTCCATGAACTTT TATTGAAATGACGGAAAGTGA [SEQ ID NO:681] [SEQ ID NO:682] ORF 29 CCCAGTGAAAAGTGAAAAAGT CCCAGTGAAAAGTGAAAAAGT [SEQ ID NO:683] [SEQ ID NO:684] ORF 529 CTGGAAAGCAAATGGAAAATC CTTTCAATTTCAATGGTCAACA [SEQ ID NO:685] [SEQ ID NO:686] ORF 3792 AAATACTCGGAGGTGCAAAAT ATCTGGCAACTTTCCATACCT [SEQ ID NO:687] [SEQ ID NO:688] ORF 3840 TCAAATACTTGTCCGCATTTC GCATATTGATAGTGCGTACCG [SEQ ID NO:689] [SEQ ID NO:690] ORF 4101 AAAAGGAGGCATTTGAATGAA CGTTGTTTTTCTCCACCAGAT [SEQ ID NO:691] [SEQ ID NO:692] ORF 3103 TGAAGAAGGTTGAAAGCAATG TTATAACCCGCAGAATTAGGG [SEQ ID NO:693] [SEQ ID NO:694] ORF 1490 TACGCTATTCATTGCGTCTTT CCAATGGTTATGTTTGGGTTA [SEQ ID NO:695] [SEQ ID NO:696] ORF 2217 CCAACTGTACTGAAGGATTGG GATGGTTGTAGGTCAGGGTTT [SEQ ID NO:697] [SEQ ID NO:698] ORF2969-2968 CGCTGGAAAGATGGTAACTCTA GATTAATTCTGTGGCAGAACG [SEQ ID NO:699] [SEQ ID NO:700] ORF 4457 ACAGGGGTAGGTTTAGCACAT CGTTTTCAGAAGTTTGATCCAT [SEQ ID NO:701] [SEQ ID NO:702] ORF 3184 TACCAATTACGGTGGTTCTCA CCACATCCAATTGCATAACAT [SEQ ID NO:703] [SEQ ID NO:704] ORF 148-149 AAGAACATCTTCCGCTTTGTT GATGCAAGAGCCATAACACTC [SEQ ID NO:705] [SEQ ID NO:706] ORF 3175 CAGCAGCAAGAGAGATTTTTG AATGGATTTCGTTCGTTGTTT [SEQ ID NO:707] [SEQ ID NO:708] ORF 2858 CGGAATATCGGTAGATGCTTT ATGAATCCTACCACTGCGATA [SEQ ID NO:709] [SEQ ID NO:710] ORF 1384-1385 TTCAAAGGAACAAACATTTCG GACAGCATGAAAAGGAGATCA [SEQ ID NO:711] [SEQ ID NO:712] ORF 2541 GAGAGCTTACTTTCCCACTCAG CTTCATCAATACCCGACAAAA [SEQ ID NO:713] [SEQ ID NO:714] ORF 2819 AAATTTTTCAAGGAGGAGCAA CAATGTCTCTTCTTTCGCTTTT [SEQ ID NO:715] [SEQ ID NO:716] ORF 2262 GTTCAAGATGGACTGCTCAAA ACACAGGATTAGCACCAACAA [SEQ ID NO:717] [SEQ ID NO:718] ORF 817 ATGCATAGAAAAGAGGGAGCA CGGCATTAGCAACAGAACTAT [SEQ ID NO:719] [SEQ ID NO:720] ORF 757 CCATTTATTTCCCGCTTTCTA AACATTCAGACGACGGAACTC [SEQ ID NO:721] [SEQ ID NO:722] ORF 2013 CAAGAAATTCCGTTATGCTGA GCGACTTCGGTGACTGTATTA [SEQ ID NO:723] [SEQ ID NO:724] ORF 2076 TAACCAATCGTGGAATTTTGA TGCATTACGAGAAGTGACACA [SEQ ID NO:725] [SEQ ID NO:726] ORF 2013 ACCTGTGTCACACTCAATGGT ATCATGATTGGAGTGGTCCTT [SEQ ID NO:727] [SEQ ID NO:728] L. innocua Lin0035 TGACACAGGAGTTTGTGGTCC ATGATGGAGAGCAGCAACTATT [SEQ ID NO:729] [SEQ ID NO:730] Lin0038 ACCCTGTACTGCAATGGTCTTT AATGTTGCCCCTGACTGTAAAC [SEQ ID NO:731] [SEQ ID NO:732] Lin0060 AAGAGAACGAGCAAATGGTATTG TCAACAAATTACGTAAAATAGCC [SEQ ID NO:733] [SEQ ID NO:734] Lin0062 AATATTGAACAAGCGGAGTGGT GAATTACAGTCACTGCGACCAA [SEQ ID NO:735] [SEQ ID NO:736] Lin0064 GGGTGGAGCACTTCAAGTTT TCCCCTTTCTAAAGCTGCTC [SEQ ID NO:737] [SEQ ID NO:738] Lin0065 GTAATGAACAAGATATACAAAAGGG TTTTCGTTCCTTCTCAATCTTT [SEQ ID NO:739] [SEQ ID NO:740] Lin0072 GCTGTATCACAATTACCTGGCA TGACAAATCTTTCGAGTTTAACTAT [SEQ ID NO:741] [SEQ ID NO:742] Lin0073 ACGGGCAGAAGAAAAGAGAC TAAGGAGTCGATTCCCCTTG [SEQ ID NO:743] [SEQ ID NO:744] Lin0197 TCGAGATGCAGAAACCAAAGTA ATGTAAATCCCACATAAACGGC [SEQ ID NO:745] [SEQ ID NO:746] Lin0198 AACCAAGAAGATGCGATGAAAT CCGGTAAAGAGTAAACGCAAAT [SEQ ID NO:747] [SEQ ID NO:748] Lin0199 GGAGCAGGAATCATCCAAATAC CAGAAAATAATTGTTTGCCGAC [SEQ ID NO:749] [SEQ ID NO:750] Lin0307 GCAGAACGAGGCATGTTTTA CTGAATTGCAGAAGCACCAT [SEQ ID NO:751] [SEQ ID NO:752] Lin0308 GAAAAACCTTGTTTCGGAATTA CGACTTTGCCAGAAACATACAG [SEQ ID NO:753] [SEQ ID NO:754] Lin0332 CGCAATGACTCCGTTTATCA TTTGGACAACATGGGTGACT [SEQ ID NO:755] [SEQ ID NO:756] Lin0338 TAATACGCAAGGAGATAATGCGT TTTGTGCCATTTGATGGAATAC [SEQ ID NO:757] [SEQ ID NO:758] Lin0372 GCAAATGGAAACCAAATTAACAA GTAATAGCGTCCCTGTTTCGAC [SEQ ID NO:759] [SEQ ID NO:760] Lin0397 ATCCAAAAAGAAAATCAGATGGA TCAATCCCAAGGAATCTCACTC [SEQ ID NO:761] [SEQ ID NO:762] Lin0398 TGAAATTAGCAATGCAAGGTGT TCCCTCGCTGGTTTTAGATAGA [SEQ ID NO:763] [SEQ ID NO:764] Lin0399 CCAATATACCCAGCAGTAGCTTG CGAAATTCCTCTGCATATTTCC [SEQ ID NO:765] [SEQ ID NO:766] Lin0415 TCAATCAGCAAAAGCAGGACTA GTTGCCGTAACTCCTTTTAACG [SEQ ID NO:767] [SEQ ID NO:768] Lin0453 ACAAATGATTTTCGTGTGGGAT TAAATTTCAGTCGCGCTGTATC [SEQ ID NO:769] [SEQ ID NO:770] Lin0454 ACGGCTACACAGATGGCTTATT GAGGATACTTGGGATTCTGTCG [SEQ ID NO:771] [SEQ ID NO:772] Lin0455 GAAGACGAATATTTCGAGGCG CAAATCTTGTTCTACACTGCCG [SEQ ID NO:773] [SEQ ID NO:774] Lin0465 TCTAGCAGATTGGGAGATAGGC GCAAACTTTCCATGAGTGCATA [SEQ ID NO:775] [SEQ ID NO:776] Lin0476 CAAAATCATGTTGATTCCTGAT AAATCTCTTCAAACACATTCGC [SEQ ID NO:777] [SEQ ID NO:778] Lin0478 GGAGAACCACCTTTTGAAGC CCAAATACCTCGCCAGTCTC [SEQ ID NO:779] [SEQ ID NO:780] Lin0559 AGCGCGTATACAGATACAGCAA TGGCAATTAAAAGGAGGCTTAC [SEQ ID NO:781] [SEQ ID NO:782] Lin0661 TGGCTAATTTGACGCAATTAAA TTCACAGTATGCGATGGTAAGC [SEQ ID NO:783] [SEQ ID NO:784] Lin0665 GAAGTAAATGCGCGAACAAA TGGGATGCCATCTTCATTTA [SEQ ID NO:785] [SEQ ID NO:786] Lin0677 TAGAGAGCGAGGGGAAAAGA ATGTGTGGAGCAGATGAAGC [SEQ ID NO:787] [SEQ ID NO:788] Lin0739 TAAGCACACTTAGCTCATTGCC TGTGACCTTCCCACTAAATTCC [SEQ ID NO:789] [SEQ ID NO:790] Lin0740 TAAAGGCGATCCAATCGTAGTT TGATGGCGCTAGTTCTTTACCT [SEQ ID NO:791] [SEQ ID NO:792] Lin0772 ATCGGAAAAATCCAAGATGC CGCCCAGATGCAGTTCTAA [SEQ ID NO:793] [SEQ ID NO:794] Lin0801 AAATGGATGGAATCAATGGT ACGCCATTCCTTTTATTTTT [SEQ ID NO:795] [SEQ ID NO:796] Lin0802 AGTACAGCGATAGGAAGGCAAG AAGCTCTTGTACCTGCTCAACC [SEQ ID NO:797] [SEQ ID NO:798] Lin0803 GATGAAATACGACGGTGCAA TCCTTAAAGTCCACCGGATT [SEQ ID NO:799] [SEQ ID NO:800] Lin0803 CCGATAAAGATGGCAATAGA TCGTATCCACTGTTCCTGTC [SEQ ID NO:801] [SEQ ID NO:802] Lin0833 GAAGAAGAGTGTGGAGGTCGTT ATCACCAAACATGAAATATGCG [SEQ ID NO:803] [SEQ ID NO:804] Lin0834 AAAGAAGGGGATGCTCTAAAAG ATGCAAATGTGCTTCAGGATTT [SEQ ID NO:805] [SEQ ID NO:806] Lin0835 TCCAGCTGAGCTAGTAGATTTGAA CACAATTTATTTTCTCTCCCCG [SEQ ID NO:807] [SEQ ID NO:808] Lin0865 GCGCTACAGAGCAAAGTGTAGA CGAGTTTCACCACCACCATAAT [SEQ ID NO:809] [SEQ ID NO:810] Lin0867 TTTTAGTTTCCCCAATTGATGC TTCCTAGCGCTTGTTGTAATCC [SEQ ID NO:811] [SEQ ID NO:812] Lin0868 TTTATCTTGCAAGCCTATGGTGT ACTCCTGATGGCACATTCATTA [SEQ ID NO:813] [SEQ ID NO:814] Lin1065 TTGCTACACTGCGCTCTTATGT TGCGTAAAGCTACATTCGAAAA [SEQ ID NO:815] [SEQ ID NO:816] Lin1066 GCTGCACATGAACATTCAGACT TTAAAGAGGTCCAACCAGGAAC [SEQ ID NO:817] [SEQ ID NO:818] Lin1067 TTGCCTTTTGCTTCCCTTATTA GTATAAGCGCGTGTACCATCTG [SEQ ID NO:819] [SEQ ID NO:820] Lin1068 AAGGGGAAGAAGCTAAAATTGC GTACCTTCCAGCGCACTAAATC [SEQ ID NO:821] [SEQ ID NO:822] Lin1069 AATGGGGAAGTCCTCATCTTTT ATTCCCAGCAATCAACCATATC [SEQ ID NO:823] [SEQ ID NO:824] Lin1073 AGGCGAGAAATATTGGAATACA AAAACAACTTGGCATGGTACG [SEQ ID NO:825] [SEQ ID NO:826] Lin1082 TTTAATAGAATGTGCCGCAAATAA TATTACGCTCTGCCATATGTTC [SEQ ID NO:827] [SEQ ID NO:828] Lin1083 TCATTTATGGGCCCCTCTTA AGGATGGCTCTCAAGGAAAG [SEQ ID NO:829] [SEQ ID NO:830] Lin1084 TCATGCTACAACCCTAGGTGAG TAACGCACCTCCAAATTCATCT [SEQ ID NO:831] [SEQ ID NO:832] Lin1090 TGAAAACATGGGAGATTCAAA GGAAAACCATCTTCCCATTC [SEQ ID NO:833] [SEQ ID NO:834] Lin1099 CAATCAAGCAGGTGTTCATCAT AAAAACTTTCCCAATTTGCTCA [SEQ ID NO:835] [SEQ ID NO:836] Lin1204 AGCAGTTCGATTGGAACGTAAT CCTTGTGGATAATGAATTTCGG [SEQ ID NO:837] [SEQ ID NO:838] Lin1210 TATGAATCAATTTGCTGGTAAGC CGAATTCAGCACAATTCTTCTCT [SEQ ID NO:839] [SEQ ID NO:840] Lin1211 GCGAAAGAAATCATTGTTGATG GCGTGATAATATCCTTGCTCCT [SEQ ID NO:841] [SEQ ID NO:842] Lin1212 AAAGATATCTCCCCGAACTTAGC CCAAAACCAAAATGCTAAGTAAAA [SEQ ID NO:843] [SEQ ID NO:844] Lin1241 CAGATAAACCCGCACAAATA TCATATATCGGTGGCATTTC [SEQ ID NO:845] [SEQ ID NO:846] Lin1258-57 TTATGGATTTGTCAGGTGCT TCAAAGCATGAATCATTTTG [SEQ ID NO:847] [SEQ ID NO:848] Lin1258-57 AAACAGTCGTGAAGTTGCTG CTTATGTGCGGTCAAGTCAT [SEQ ID NO:849] [SEQ ID NO:850] Lin1260 TGAGGAGGGAACACAATGAA CACTGCCCACCAACTTTATG [SEQ ID NO:851] [SEQ ID NO:852] Lin1262 GGTCAGCAAGTTTGACAGGA TTTCTGCGAGCTCTTAATGC [SEQ ID NO:853] [SEQ ID NO:854] Lin1298 GCATTTGAAGGAAGAAATTGAAG TGCGCTATTGTTATAGTATCGTT [SEQ ID NO:855] [SEQ ID NO:856] Lin1299 AAAAGAATGGGAACTAACCAATGA AGTACTCAATAATCACTGATGCTGT [SEQ ID NO:857] [SEQ ID NO:858] Lin1300 ATTGGTAATAACGCCGATTACG CGTATTTTGTTGTCGATCCTGT [SEQ ID NO:859] [SEQ ID NO:860] Lin1328 GCTTCCCAATTTAAAAACCCTT CGACGTCATATAATCCACCAGA [SEQ ID NO:861] [SEQ ID NO:862] Lin1452 AAAACGAAACCGATATTGTAAA ACGTTCCAATGAAAGTTACCGT [SEQ ID NO:863] [SEQ ID NO:864] Lin1621 GGATACAGGGGAGAACAAGC CTGTGACACCTGTGCCTTTT [SEQ ID NO:865] [SEQ ID NO:866] Lin1703 AAAAAGTTAAATCTGCATCAGTGT TCACCAACAGATACACCATGTTT [SEQ ID NO:867] [SEQ ID NO:868] Lin1723 ATGGTGGTGGTTTGATGAAG TTTACCGGTGACAATTAAAGGA [SEQ ID NO:869] [SEQ ID NO:870] Lin1728 TAAGGCACCAGTCACTCGAC CTTTAGCATTTGCTGCATCC [SEQ ID NO:871] [SEQ ID NO:872] Lin1731 GCGATGGCTTTCTAAGTATTGG TTCCTGACACATTTGTCGATTC [SEQ ID NO:873] [SEQ ID NO:874] Lin1744 AATACAGAAACGGCGAGGAA TACTGATGCAGCCCAGTTGT [SEQ ID NO:875] [SEQ ID NO:876] Lin1745 GCATAAAAGAGCAAGCACTCAA TTCCTTAGCTTTAACCTTCGCTT [SEQ ID NO:877] [SEQ ID NO:878] Lin1747 TGGATTACTATCCTGAGCAGTCT TTTTCCGCGATATTTGTATCCT [SEQ ID NO:879] [SEQ ID NO:880] Lin1756 CAGATAAACCCGCACAAATA TCATATATCGGTGGCATTTC [SEQ ID NO:881] [SEQ ID NO:882] Lin1811 TTTTAACAATGACGGCTCCA GCGGGTTTCGAAATGATAGT [SEQ ID NO:883] [SEQ ID NO:884] Lin1813 ATTGATGTTGGAACAAATGC AAAAATCGCCTGCTTTTAAT [SEQ ID NO:885] [SEQ ID NO:886] Lin1898 TCCCTTGAACAAGAAAACAA AGCCATACGAAAAGACATCA [SEQ ID NO:887] [SEQ ID NO:888] Lin2100 GGTGAAAAAGTTACTGTGAACC CGTAAATTTAAGCTACTCACCG [SEQ ID NO:889] [SEQ ID NO:890] Lin2373 GGCCCGTTAGCTTACAAATA CCTAACGGTGGGGTTAAGG [SEQ ID NO:891] [SEQ ID NO:892] Lin2383 TGATACGAACGCAAGAACAACT GTAATTTGTCCCAGACACCCAT [SEQ ID NO:893] [SEQ ID NO:894] Lin2394 CACCCAATCATCCAGTGTTAGA CAGGGTCAATAAAAACAGGCTC [SEQ ID NO:895] [SEQ ID NO:896] Lin2394 CTAAAGACAATCCGGCTCTT ATGAGCATTGTTGTCTGCTC [SEQ ID NO:897] [SEQ ID NO:898] Lin2394 AGAAGTGAAAGCGACCGAAA TGGGTCCGGAAACTCAATTA [SEQ ID NO:899] [SEQ ID NO:900] Lin2394 AGAATGGAACAGTGCGGTCT CCAATTAGCTTGCTGGCTTC [SEQ ID NO:901] [SEQ ID NO:902] Lin2397 ATCGAAGGACGTCATGAACA TTTCTTCCCCACGATGTAGA [SEQ ID NO:903] [SEQ ID NO:904] Lin2405 CAAGGAGGAACAAGCATGAA AACAGCATATACGCCCGATT [SEQ ID NO:905] [SEQ ID NO:906] Lin2425 AGGATCCCGGAAAAGGATATTA TTGTTGTTCCAGCGTTAATTGT [SEQ ID NO:907] [SEQ ID NO:908] Lin2494 GCCCTCCACACAAAAACTTC GTTTGGGGGAGGGTGAGT [SEQ ID NO:909] [SEQ ID NO:910] Lin2603 TGTTTCCAAATCGGAGCAT ATTCCAGCTCCCAATTTTTG [SEQ ID NO:911] [SEQ ID NO:912] Lin2604 GCAATCACCTCCAATCAAAA CCGATTTCGGAACGTAATTT [SEQ ID NO:913] [SEQ ID NO:914] Lin2693 GGCAGCTGGTTTTGCTAACTAT CCATGAAAATGTTTTTAACCCA [SEQ ID NO:915] [SEQ ID NO:916] Lin2724 CGTTATAGCGCTAAATCTTATACA CGCTTGAATCAGGCTATCATAA [SEQ ID NO:917] [SEQ ID NO:918] Lin2741 TGACACAATACCACTACCTCGC CTGTTTTATTCGTCAGAGGGAAA [SEQ ID NO:919] [SEQ ID NO:920] Lin2743 TCGTACAAAAACCAGCATCTTG GCAAACTACTGTCATGTCGTCC [SEQ ID NO:921] [SEQ ID NO:922] Lin2744 GCAATATGAGCCATGTTGAAAG GGTGGGTAGCCCATTACACTAA [SEQ ID NO:923] [SEQ ID NO:924] Lin2839 TGGGCTTAGAATGGTCAATAAAA CTTTTTCATCGTTAACTCGGCT [SEQ ID NO:925] [SEQ ID NO:926] Lin2918 AATTTACCAAGATGCTTTAGGGA CCCCAAATCAGTTAAAGATAGTTCT [SEQ ID NO:927] [SEQ ID NO:928] Lin2941 CAAGGAATTCAAGGTGTTAAGGA AGCCAGTTTACAAGAAAGTATTCC [SEQ ID NO:929] [SEQ ID NO:930] Lin2945 AACAAACAGAGAGGACGAGAGC ATTGAATCCGCTAATTCTTCGT [SEQ ID NO:931] [SEQ ID NO:932] L. m. EGDe Lmo0017 TCTTAAAAATGCAGGGGTTGAT GCCGAATGACCTGAAACATAGT [SEQ ID NO:933] [SEQ ID NO:934] Lmo0036 TTCCGGTTATTAATGGGATGAG AGCATCAAGCACTTCGTCAGTA [SEQ ID NO:935] [SEQ ID NO:936] Lmo0037 TAATATCGCGGCTTTTCTGTA TTCCAAAAACAGCTGGTAAA [SEQ ID NO:937] [SEQ ID NO:938] Lmo0038 CGCTTGTAACGACAGAAGAATG ACACCAACCACTTCACAGTTTG [SEQ ID NO:939] [SEQ ID NO:940] Lmo0039 CTGAAAAGAATCCAGCAATG CCACCCCTGTTAAAATAACC [SEQ ID NO:941] [SEQ ID NO:942] Lmo0040 AATGAGTAATGATGATGCGTGG TTCGCTCTCTGTTTGCGTAATA [SEQ ID NO:943] [SEQ ID NO:944] Lmo0041 GCATACAGAGCTAAAACCGTCC ATTGCAATTGTAGAGATGCGAG [SEQ ID NO:945] [SEQ ID NO:946] Lmo0066 GGAGTCAGTATTTTCTGCCCAC GCCCTTCACATTCAAATTATCC [SEQ ID NO:947] [SEQ ID NO:948] Lmo0067 ATTGGAAGTGTAACGCGAGAAT TAGATACCTGCTAGGCTCCCTG [SEQ ID NO:949] [SEQ ID NO:950] Lmo0068 AAGATATGCCATTTTTGAAGGG TCATTTCTCCCATAATGCACAA [SEQ ID NO:951] [SEQ ID NO:952] Lmo0069 TGTGGGTGTTTCAGGAAGTTTA CTATTTCGCTTCCACCCTA [SEQ ID NO:953] [SEQ ID NO:954] Lmo0070 TTTGTGACTTGGCTACAAGGTG TCCCATAGAACACAATGCGATA [SEQ ID NO:955] [SEQ ID NO:956] Lmo0071 CGAGGTAGAAGGAGTCACGTTT AGGCACATTTCCCACATAATTC [SEQ ID NO:957] [SEQ ID NO:958] Lmo0072 AAACCTTAGAAGTGTATGAGAACGA CAAAACCTATTATCCCTCCACCT [SEQ ID NO:959] [SEQ ID NO:960] Lmo0073 ACATATTAGATTTCACAATGGGCTT TATAAGTAAAGGCAGGGCTGGA [SEQ ID NO:961] [SEQ ID NO:962] Lmo0074 TTTACCTTCTTGAAAATGAAATCT CTTGCAGTATGCAGTGAAAAGG [SEQ ID NO:963] [SEQ ID NO:964] Lmo0079 TCAATAGCCAAACAGGCACTTA TTTTCCCTTGTTGAACCTCATT [SEQ ID NO:965] [SEQ ID NO:966] Lmo0080 AAAAGGGCTTCAAAGTGATGAA GTTATCGCTTTAAATGGTGCGT [SEQ ID NO:967] [SEQ ID NO:968] Lmo0081 GCTCAAAGAAGGGACAGAAAAA GGACTATCTGGAATACCCACACTC [SEQ ID NO:969] [SEQ ID NO:970] Lmo0082 CCAACAGGAGCTAACATGAA TGGTTAGGAAGATTGGGATT [SEQ ID NO:971] [SEQ ID NO:972] Lmo0083 GAAGGCTTAATAACCCCTGACC CGCAACCTTCTCCTCATAAATC [SEQ ID NO:973] [SEQ ID NO:974] Lmo0084 CGAAAGATCGAAATGAAATG CGATGCCAAGTTCTTCTAAA [SEQ ID NO:975] [SEQ ID NO:976] Lmo0094 TGATATTGGTTTATTGATTGGCTT ACTCGCCACAAACAAACTACAA [SEQ ID NO:977] [SEQ ID NO:978] Lmo0106 AGTTGTCCGGGAGTGGTAGATA ACCACCAATTGCAATAATTTCC [SEQ ID NO:979] [SEQ ID NO:980] Lmo0110 GCAGCTCCAAAAGATTGTTACC TTTGAACAATTTCATCTGCCAC [SEQ ID NO:981] [SEQ ID NO:982] Lmo0141 GATCCAATAGAGCTGTTTCCCTT TTCAGCTATTTCATCTTCGTTATTT [SEQ ID NO:983] [SEQ ID NO:984] Lmo0143 GGATAGGAAAGGTTGGAAGA TAGGGAGCCCAATTTTTATC [SEQ ID NO:985] [SEQ ID NO:986] Lmo0144 TGGAAGAACAAGAGATCATTGAA TTCGTAGAATAAGGTTGCACCA [SEQ ID NO:987] [SEQ ID NO:988] Lmo0146 TGAAAGCAGATGGAGAAATGTT TTGTGCTCTGTTTTACCTGTTGA [SEQ ID NO:989] [SEQ ID NO:990] Lmo0147 GTTTATTTCGAGCGGAAAGT CATCAGGTTAATTCCGCTTT [SEQ ID NO:991] [SEQ ID NO:992] Lmo0151 TGTTGAATAAAACTAGAGGCGAAA AGCTACTTTATCTTTAAACTTCGCA [SEQ ID NO:993] [SEQ ID NO:994] Lmo0160 CAGAAACAATTGATGTGGGTGT CTCCTGCTCCGTTGACTAACTT [SEQ ID NO:995] [SEQ ID NO:996] Lmo0171 AACGTATGAAGCGACGATAA AAAACCCCACTTGAATTAGC [SEQ ID NO:997] [SEQ ID NO:998] Lmo0172 CCGCATTAATGAAACAAGAA TGGTAGAATGTTTCGCACTT [SEQ ID NO:999] [SEQ ID NO:1000] Lmo0175 CAAGTGGCATGAACTATACGGA ATGATTCACAGTGATGTTTGCC [SEQ ID NO:1001] [SEQ ID NO:1002] Lmo0200 TCCAAACCCTACAAAAACAA GGATTGACAAAATGGAACAA [SEQ ID NO:1003] [SEQ ID NO:1004] Lmo0201 CTGACACAACAAACCTAGCAGC TGAATTTTGTTTTCACACTCGG [SEQ ID NO:1005] [SEQ ID NO:1006] Lmo0202 ATGCAATTTCGAGCCTAACCTA GGAGGATTTTCTGCATTCACTC [SEQ ID NO:1007] [SEQ ID NO:1008] Lmo0203 TGAAAAGTTATGTCGGAAACCC TGAAATTCTTTTTGTCCCCATC [SEQ ID NO:1009] [SEQ ID NO:1010] Lmo0204 GAGGTAAATGCTTCGGACTT AGGCGATCAATTTCTTCTTC [SEQ ID NO:1011] [SEQ ID NO:1012] Lmo0205 GTATGTGCTTGATCGCAAGTGT AAAATTATTGGCGTGCATAGGT [SEQ ID NO:1013] [SEQ ID NO:1014] Lmo0206 TTAGTAATCGCGTTATGTTCCG AGCAACTTTTTGTTCGTCTTCA [SEQ ID NO:1015] [SEQ ID NO:1016] Lmo0252 TTTTGGAAGAGCGGTTCAGTAT AGGTGATTTCATCCTTTTCCAA [SEQ ID NO:1017] [SEQ ID NO:1018] Lmo0253 CGTAATGGATCAAAGTGGGATT AAACAGCTTCATCACACGCTAA [SEQ ID NO:1019] [SEQ ID NO:1020] Lmo0255 GCATGTGGAAGTGATTCAAGTG TTCTTCTTGAACCCTTGAGCTT [SEQ ID NO:1021] [SEQ ID NO:1022] Lmo0257 GTATAGTTGCGCCAATTCATCA AGATGTCGCACCTTTTCTAAGC [SEQ ID NO:1023] [SEQ ID NO:1024] Lmo0262 TTGGGTGTATCTTCCAATCAGA CGCTTCTACTATCGGTTGAACA [SEQ ID NO:1025] [SEQ ID NO:1026] Lmo0263 GGGTTACAAAGCATAAAAACGC ATGTTAAATTTGGGCTTGCGTA [SEQ ID NO:1027] [SEQ ID NO:1028] Lmo0264 CGATGTTTCTCCACTTACTGGTT AGCAGGCATTTTATCTATCCCA [SEQ ID NO:1029] [SEQ ID NO:1030] Lmo0304 CCTTGGATAGCTGTGCATGATA CGAATTTCTTGAATGCGTTTCT [SEQ ID NO:1031] [SEQ ID NO:1032] Lmo0310 ATGGAAGAAGTCCTCATTTTGC CTTCTCTCCCCACACTGAAGTT [SEQ ID NO:1033] [SEQ ID NO:1034] Lmo0311 TACACTTGCCGGAAATAACAAG CAGCGATTTTATTATTTATTACAGC [SEQ ID NO:1035] [SEQ ID NO:1036] Lmo0312 AGAACTATTTGACGCCTTTCCA ACAATTTCACCTTTCGTTTCGT [SEQ ID NO:1037] [SEQ ID NO:1038] Lmo0313 TTTCATCCAGATATGGTAGGGG TTTCAAATCCTGGAATAACTTCCT [SEQ ID NO:1039] [SEQ ID NO:1040] Lmo0320 GGTGTTACAGGTTTGGAGCG TCAGGAACGGAAACGGGTG [SEQ ID NO:1041] [SEQ ID NO:1042] Lmo0333 AATCCGGTTATTTGGTATGACG GCAACTGTATAATCTCCGCCTT [SEQ ID NO:1043] [SEQ ID NO:1044] Lmo0334 TGCAACAGAGCTTAGTCAGAAG CAATCTGCGAATCGTCTTCATA [SEQ ID NO:1045] [SEQ ID NO:1046] Lmo0338 GGTGGAAAGTTTGATTGGTACATAG GCTTCAATTCATCAGACCTTCTAA [SEQ ID NO:1047] [SEQ ID NO:1048] Lmo0378 TGAGAAAACTTGATTTCAGCTACA GAATTGCAAACAAATCTCCCTC [SEQ ID NO:1049] [SEQ ID NO:1050] Lmo0379 TCAAAAATAAAGTCTCAAGGACA GCACAACCATAACTCCGTGATA [SEQ ID NO:1051] [SEQ ID NO:1052] Lmo0380 AAGATGGAACCCTCATTCATAA ATACATTCCTGCATCTCCATCC [SEQ ID NO:1053] [SEQ ID NO:1054] Lmo0381 TGAACTTCAAAAGAAAATTGATGA GATGCATCAAAAGAACATTCAA [SEQ ID NO:1055] [SEQ ID NO:1056] Lmo0409 TGCAAAAATTAACCTCGCTACA CGGTTGTGTTATGAAGCCACTA [SEQ ID NO:1057] [SEQ ID NO:1058] Lmo0419 TTACCGGATGTATTTACCGCAG GGCGGTTTGTGAGTTGAATAA [SEQ ID NO:1059] [SEQ ID NO:1060] Lmo0433 TAACATCAGTCCCCTAGCAGGT TCCAATAGTGACAGGTTGGCTA [SEQ ID NO:1061] [SEQ ID NO:1062] Lmo0434 AAAAGCAAGATTTCATGGGAGA TCTCACTCTTGCATAAGCGGTA [SEQ ID NO:1063] [SEQ ID NO:1064] Lmo0440 TGACAAACAGAACATTAACTACCAA TTTGAAATCGAATGTTAAATCCA [SEQ ID NO:1065] [SEQ ID NO:1066] Lmo0444 TGAGAATGGTGTCGGTGAATTA AGCATTTGTGCCACTGTAAATG [SEQ ID NO:1067] [SEQ ID NO:1068] Lmo0445 GGACCTGAGGAACAAGTTAGGA TTCATACCCATTAATATCCGCC [SEQ ID NO:1069] [SEQ ID NO:1070] Lmo0446 GAAATCTTCTACAGACGGTGCC AAAACGTTCTGGCGGAGTATAA [SEQ ID NO:1071] [SEQ ID NO:1072] Lmo0447 GTATTGTGGGTATTCTGGGCAT AGTTTGCGCCATCGTTATAAAT [SEQ ID NO:1073] [SEQ ID NO:1074] Lmo0448 TTCATGCTTGCTTATATGGGTG TCCGTCCTGGAATTTGATATGT [SEQ ID NO:1075] [SEQ ID NO:1076] Lmo0459 AAGGGCGACTACTCACTTATGC TAACCGATGATGGATATCACGA [SEQ ID NO:1077] [SEQ ID NO:1078] Lmo0460 TCCAACCTTATGGAGGTTGATT CATTATCAGAAAACATGGCAGC [SEQ ID NO:1079] [SEQ ID NO:1080] Lmo0461 TTGCTAGTAAGTGTCATTGGAATC AGACCCGTTTAAAGGTGACTGA [SEQ ID NO:1081] [SEQ ID NO:1082] Lmo0462 GTATGGTGATTTTTAGCGGAGG TGTCTCCTTGAGGACTTCCAAT [SEQ ID NO:1083] [SEQ ID NO:1084] Lmo0463 ATGTTCCTGTTATCGGCTGAAG CAACCAAATAAGGACGAGCACT [SEQ ID NO:1085] [SEQ ID NO:1086] Lmo0466 GCAAAAGGAAAAATCCAAGAGA ACATGCTTTTTCATGAATTGGA [SEQ ID NO:1087] [SEQ ID NO:1088] Lmo0467 GCGAATATTGCACTTGTTGAGA TACGTCCAAAAGGGTCTACGTT [SEQ ID NO:1089] [SEQ ID NO:1090] Lmo0469 AATAATTGCGGATTTGGAGAAA GGCCAAGTGAATGACCATAGA [SEQ ID NO:1091] [SEQ ID NO:1092] Lmo0470 CAAACACCGTTTGATAAAGTGC TGAAGACTCGTAATGACCCACA [SEQ ID NO:1093] [SEQ ID NO:1094] Lmo0471 GGAAGGAAAGGTATTAATCGGG TTTTTGAAGGATATTGTGCTCG [SEQ ID NO:1095] [SEQ ID NO:1096] Lmo0472 AAAGTGACTAGCGAAGAGGGTG TGCATATCTGGCTTCGTATTTG [SEQ ID NO:1097] [SEQ ID NO:1098] Lmo0473 TAAAACAGGCACTTACGCTGTG GCCCTACTTTGGCTAATCTCAA [SEQ ID NO:1099] [SEQ ID NO:1100] Lmo0474 ACATTCGTTTGAGTGTAATCCA TCAATATCGCTCCATTGACTTG [SEQ ID NO:1101] [SEQ ID NO:1102] Lmo0476 GCATCAAGGTGGTTCGAGTTAT TTGCTTCAGCCAAAATCTCATA [SEQ ID NO:1103] [SEQ ID NO:1104] Lmo0477 TTCTGCTTAGTGTTATTGGATACG CACCTTCTGTTTGTCCCGAAC [SEQ ID NO:1105] [SEQ ID NO:1106] Lmo0478 GTAATCCCTAAACATACGGCGA TCCAATTGTTCTTGTAATGATGG [SEQ ID NO:1107] [SEQ ID NO:1108] Lmo0492 TCATTCAAGCAAAGTCATCCAC CTGTTTATTAATGGCTGCGACA [SEQ ID NO:1109] [SEQ ID NO:1110] Lmo0493 AGTGGTATATTGCAGCTGAGCA GTAGGTGGAAAAACTTCGGATG [SEQ ID NO:1111] [SEQ ID NO:1112] Lmo0497 ATCACCGTTTTAGCCGATTATG TCAGAAGGGATTGCTCTAGTGA [SEQ ID NO:1113] [SEQ ID NO:1114] Lmo0514 ATCTCTATGCGCAAAACTCCAT ATCATATGTCCCGCTTGAGATT [SEQ ID NO:1115] [SEQ ID NO:1116] Lmo0525 AGGGATTATTATTGGCCGACTT TGTGTCTGTCCATGTCATCAAA [SEQ ID NO:1117] [SEQ ID NO:1118] Lmo0533 GGGTATTGTCGCAGGTGTTAGT CTAAAGTTTGTGCATTGCGTTG [SEQ ID NO:1119] [SEQ ID NO:1120] Lmo0549 TTTATCCCTTTTTCCAAAGCTG TTGTAAGACACAACTTGGGGTG [SEQ ID NO:1121] [SEQ ID NO:1122] Lmo0550 GCTAGTAGTCCAATTAATGTGG GAATAAAACTAAGCCAATTCCG [SEQ ID NO:1123] [SEQ ID NO:1124] Lmo0610 TTTTATGCCACTCAAATCCCTT TCTTCGGTAACGGTAGTTTGCT [SEQ ID NO:1125] [SEQ ID NO:1126] Lmo0630 GGCGTGAATAAGTGGTCTAAGC TCATTTTCGACGCTCTCAAGTA [SEQ ID NO:1127] [SEQ ID NO:1128] Lmo0631 TGCGATTCTACAATTAGTGAATGTT TAGTGCCACTGTTGCGATGT [SEQ ID NO:1129] [SEQ ID NO:1130] Lmo0632 TTGGAGAGCCAATATCAGGTTT TCATCTATGTCTTGCCCTTCCT [SEQ ID NO:1131] [SEQ ID NO:1132] Lmo0633 ACGTTTCGGCTTTCTTATTT TGATTTCTGAAACGCTCATT [SEQ ID NO:1133] [SEQ ID NO:1134] Lmo0634 AGAAGTGGATTTTGATGGGCTA CATTGGTCGCTGTTATTTCTGA [SEQ ID NO:1135] [SEQ ID NO:1136] Lmo0638 AAAAATTATTTGTGGGGGTTTG TACCTACACCGAGAGAAGCACA [SEQ ID NO:1137] [SEQ ID NO:1138] Lmo0638 TGCTTGGTTTAACGGATTATCA GGCTGTTTGTAATTTATTCGTGG [SEQ ID NO:1139] [SEQ ID NO:1140] Lmo0673 CAGCATCCACGAATTATCAAAA TTCGCTTACAAGGAACCAATTC [SEQ ID NO:1141] [SEQ ID NO:1142] Lmo0732 ATTAGGTATGTCTCTTGCTGG AGAGTTCGTCGATAAGGTGC [SEQ ID NO:1143] [SEQ ID NO:1144] Lmo0733 GCAAGAAGAAATTGCCATCAA CCTCCTATAAGGATAATCGGTGC [SEQ ID NO:1145] [SEQ ID NO:1146] Lmo0734 CACTACCAAGGAGCTTTTGA ATTCAACGGGAACAATCTCT [SEQ ID NO:1147] [SEQ ID NO:1148] Lmo0735 GAAGCGATGTTTTTCATGTTGA TAGCACAAACCCCTTAACACCT [SEQ ID NO:1149] [SEQ ID NO:1150] Lmo0736 TGGAAATGATCATGTTGGAATC AAATTCTGCATCCAACCAGTTT [SEQ ID NO:1151] [SEQ ID NO:1152] Lmo0737 ATTATTAGCAGCATTCGGATCG AATGTCATTGCGAGTGTACCTG [SEQ ID NO:1153] [SEQ ID NO:1154] Lmo0738 ATTCTTAGCGTTTGGACCTC AAAGCCAACAAATCCTTTTC [SEQ ID NO:1155] [SEQ ID NO:1156] Lmo0739 GGTCGAGTGAAATATTGGGTTC TTGTTTCACAATATGGGTTTGG [SEQ ID NO:1157] [SEQ ID NO:1158] Lmo0745 AGCTTAATCGTCGTAGGAATCG ATGCTTCGGAAATTGCATCTAT [SEQ ID NO:1159] [SEQ ID NO:1160] Lmo0750 TTAAAAAGCCGAAAATGAAGGA AAGCAATAAGCTAAGGCACCAA [SEQ ID NO:1161] [SEQ ID NO:1162] Lmo0751 GATATTGCCAAGTGGTTTGACA TGGCGCCGTATTACTATAAGTG [SEQ ID NO:1163] [SEQ ID NO:1164] Lmo0752 GTAATGGTAGATCGTCGTGGGT GGCATTAACATCTTGTGGGAAT [SEQ ID NO:1165] [SEQ ID NO:1166] Lmo0753 AAAATAGCCAATTATGCGAAGG ATTTTCTTTTTGCATTCTGCCA [SEQ ID NO:1167] [SEQ ID NO:1168] Lmo0754 AAAGGCAGACATCCTTGAGCTA ATCAATGCCGGGAAGATTATTA [SEQ ID NO:1169] [SEQ ID NO:1170] Lmo0780 GGACTCATGCTAATGCATAAAAGA TCATCACTCCAAAAATCTTCGTT [SEQ ID NO:1171] [SEQ ID NO:1172] Lmo0801 TTGCGGAAATAACCCTATAAGC GGGCTATTATACGTTCCATTATCA [SEQ ID NO:1173] [SEQ ID NO:1174] Lmo0804 TTTTACGTTCATCGTTGCCTTA TGGAAGTTCTTTCTGCCATTTT [SEQ ID NO:1175] [SEQ ID NO:1176] Lmo0832 TGATTTTGGTGTCTCAATAGCA CAATGCTCGTCTCCATGTTAAA [SEQ ID NO:1177] [SEQ ID NO:1178] Lmo0833 AATAGGGGCTATTCTTTAGCGG AAAAGCACAGTCATGCGTAGAA [SEQ ID NO:1179] [SEQ ID NO:1180] Lmo0834 TGAATATGACACAAAAAGTGGTGAT TGAATATGACACAAAAAGTGGTGAT [SEQ ID NO:1181] [SEQ ID NO:1182] Lmo0835 CATTAGCATAGATGGCTTGC CGAGCTATCACCTGTTTTTG [SEQ ID NO:1183] [SEQ ID NO:1184] Lmo0838 GGAATGCCTCGCATAATATAGG CAACTGCAATAATCGAGCAAAG [SEQ ID NO:1185] [SEQ ID NO:1186] Lmo0842 AAAAACTGGTCAAGACTTCGGA TACCATTGCTATCTGTTGTGGC [SEQ ID NO:1187] [SEQ ID NO:1188] Lmo0843 CATGCTTACCGGATACCTGAAT TACAACCACCAAACCACAACTC [SEQ ID NO:1189] [SEQ ID NO:1190] Lmo0849 AAAGGAAAATGGCGCTTTAATC CCAGCTTTTTGCAGATCAAGTT [SEQ ID NO:1191] [SEQ ID NO:1192] Lmo0880 AAGCATTTTACATTGGACCGTT TTTAATTTCTGCAACGGAGACA [SEQ ID NO:1193] [SEQ ID NO:1194] Lmo0932 TTGGCAGGATATGATGAATTTCT GGTTGGTGAATCAAGTCTACGA [SEQ ID NO:1195] [SEQ ID NO:1196] Lmo0933 TGCTCACGGTAAAGCTGTTATT CCCAGAATGAAAAGAATTGTCC [SEQ ID NO:1197] [SEQ ID NO:1198] Lmo0946 GATCGGATAGAAGATGGCAAAG TTGGGGATGTTTCATTATTTCA [SEQ ID NO:1199] [SEQ ID NO:1200] Lmo1030 CCCATTACGAAACACCAATA ATCGGCTTCTTCTAAACGAG [SEQ ID NO:1201] [SEQ ID NO:1202] Lmo1031 CAGCAAAATTTAAAAAGGCTGG TTAAGAGCAGCAACCATTCGTA [SEQ ID NO:1203] [SEQ ID NO:1204] Lmo1032 CGGGACATACTGGTTCAGATTT TCTGCCAAAGGTTCTACACTCA [SEQ ID NO:1205] [SEQ ID NO:1206] Lmo1033 GACGTGGCTTATTCAGACACAA GCGAACTACTTACCACTTCGCT [SEQ ID NO:1207] [SEQ ID NO:1208] Lmo1034 ATGCTTGGTTGTTATTTTCGCT TGTCCAGGAATTAGCACAACAC [SEQ ID NO:1209] [SEQ ID NO:1210] Lmo1035 TTAATTGTGGTGCCTGTGTCTC AAAATCCCAGCCTATTCCATCT [SEQ ID NO:1211] [SEQ ID NO:1212] Lmo1036 AGAAATGGCAGTGAATCAAGGT CTTTTCGTACATCTTCTCGGCT [SEQ ID NO:1213] [SEQ ID NO:1214] Lmo1060 TAACCGAAGCAGGGTATCAAGT TTGCGTAGATTTTTCATATGCG [SEQ ID NO:1215] [SEQ ID NO:1216] Lmo1061 ATTAAAATCCCCTCTTGCTG TGATTTCTCAAGGCGATAGA [SEQ ID NO:1217] [SEQ ID NO:1218] Lmo1062 AAACCCCAAGTTTTTCAGTCAA CATTTCAAATTTACGCTCACGA [SEQ ID NO:1219] [SEQ ID NO:1220] Lmo1063 GGGAAACAAAGCTCAAATTGTT AATAATGTGTTCCGAGGTTTCA [SEQ ID NO:1221] [SEQ ID NO:1222] Lmo1076 AACTTTGCCAAATACCCATCAC ACCTGGAACCTCAGACCATAAA [SEQ ID NO:1223] [SEQ ID NO:1224] Lmo1077 TGGTGGTAATTTTGAGTTCG TTGTTTGCCTTGAGTTTCTG [SEQ ID NO:1225] [SEQ ID NO:1226] Lmo1079 CTGGTTATTGGGCAAACTTAGG TCTTTTTATCTGCTCCCCCATA [SEQ ID NO:1227] [SEQ ID NO:1228] Lmo1080 AATTCCAGTAGTTTCGGACGTG TTGGCTCATACGTAAATTCAGC [SEQ ID NO:1229] [SEQ ID NO:1230] Lmo1081 AAGAAAAACCGGAAGGATTAGC CAGCCTCATCAATATACCCCAT [SEQ ID NO:1231] [SEQ ID NO:1232] Lmo1082 TGGAAATTGTTGAAAGTAAACTAGC TGGAAATTGTTGAAAGTAAACTAGC [SEQ ID NO:1233] [SEQ ID NO:1234] Lmo1083 TTAACTTCGCAGCAGAATCTCA TCGTACGTTCATTATGTCCACC [SEQ ID NO:1235] [SEQ ID NO:1236] Lmo1084 TGTGCCGCTTTTACTAATGT GTTGCAAACTCAAACCATGT [SEQ ID NO:1237] [SEQ ID NO:1238] Lmo1085 GCTAGCTATTCGCTCTCTTTGG GGTAAATCGGCATGAAAGTAGC [SEQ ID NO:1239] [SEQ ID NO:1240] Lmo1088 ACCTCGAACGGATGTTTATT CCTTCGTTTTTATTTGCTCA [SEQ ID NO:1241] [SEQ ID NO:1242] Lmo1090 TGATGGAGCGACTGATAATTCA GGTACGCAAGTTGATCTTTTGA [SEQ ID NO:1243] [SEQ ID NO:1244] Lmo1091 TGGTAGGTGCTACCCTTACA TGATGAATAAAACCCCACAA [SEQ ID NO:1245] [SEQ ID NO:1246] Lmo1097 ACCTAAGGTGGAGTTCTGGACA CATGTCCTAGGCGCTCTTTAAT [SEQ ID NO:1247] [SEQ ID NO:1248] Lmo1099 TCTACGATGAGAACAAACGACG TCAATGTTCCTCCATGAGTTTT [SEQ ID NO:1249] [SEQ ID NO:1250] Lmo1101 AGGTGCTACCCTTACAGACGAG TCGATAATGATGAATAAAACCCC [SEQ ID NO:1251] [SEQ ID NO:1252] Lmo1102 TGAATGACATTTGTGAAATAACCTG TTTTGAACTACTCCAGCTTTACTTA [SEQ ID NO:1253] [SEQ ID NO:1254] Lmo1103 AACAGTCGCAAGATTCACAGAG GTCTGCTTGTGTGTAAACAGGG [SEQ ID NO:1255] [SEQ ID NO:1256] Lmo1104 CAGCAGAGGTACTGGCACATAG GTGTCAATCCGCTACAATCAAA [SEQ ID NO:1257] [SEQ ID NO:1258] Lmo1105 AGACACCAACAACGGAGAAGAT ATTTTTACCAATTGCTCGGCTA [SEQ ID NO:1259] [SEQ ID NO:1260] Lmo1106 GCGTTGTGATGAAGTCAAAGAC CCTTTTTACGGCTCAAAATGAC [SEQ ID NO:1261] [SEQ ID NO:1262] Lmo1107 CTACACCAGCATTTGGAACGTA CTTTTGAAGTTTCACGGCTTTT [SEQ ID NO:1263] [SEQ ID NO:1264] Lmo1108 ACCCCACCTATCGACTATGAAG TCAAATACCCCATGTGAGGTTAC [SEQ ID NO:1265] [SEQ ID NO:1266] Lmo1110 GGCTTAACGGCTGAACTCTATG TTCACTCATGTATTTCTTGCGG [SEQ ID NO:1267] [SEQ ID NO:1268] Lmo1111 AACACCGAAGCTGGTATGACTT TTCTTACCAATGAACCATTCCC [SEQ ID NO:1269] [SEQ ID NO:1270] Lmo1112 TCAAAGACAAAAGAGCGAATCA TTCACTTCGTGCAATCATATCC [SEQ ID NO:1271] [SEQ ID NO:1272] Lmo1113 GAGATTAGCCGAAGGAATCGTA TGCTGGTCTTTTCAAGACGATA [SEQ ID NO:1273] [SEQ ID NO:1274] Lmo1114 CACGTAATACCCAACATGGAAA TGTGAATCCACGAGTACCAATC [SEQ ID NO:1275] [SEQ ID NO:1276] Lmo1115 TAAACTGCTTGGAGAAACCA ATGTCTTGTCGTGATCCTTG [SEQ ID NO:1277] [SEQ ID NO:1278] Lmo1115 GGACAATGGCACTCTCCTAACT TTTAAGCATAGTCTCGTTGCCA [SEQ ID NO:1279] [SEQ ID NO:1280] Lmo1116 TGCTGCTCACTTTGGTTATGAT TGATTGCCAGAACATTTAGGAA [SEQ ID NO:1281] [SEQ ID NO:1282] Lmo1117 TGGCTTTAAATGCAAAGAGTATCA GGTACATCTTCTATCACCTCGTCA [SEQ ID NO:1283] [SEQ ID NO:1284] Lmo1118 AGGGGTCTTAAATCCTGGAATA GAAGTTTTCCGCTCCCTATTTT [SEQ ID NO:1285] [SEQ ID NO:1286] Lmo1119 GGTTCTGGTCTTGCCTTAGAACT TCTCTGGCGCTAAATCATAAGT [SEQ ID NO:1287] [SEQ ID NO:1288] Lmo1120 AAAACGAGTCCATGGGAGACTA TCATTTCTTCAACTTCATTGTGC [SEQ ID NO:1289] [SEQ ID NO:1290] Lmo1121 GCATGAAATTAGACGATAATGCAA ACTTTCTTGGCAAAATTGTAAGT [SEQ ID NO:1291] [SEQ ID NO:1292] Lmo1125 TCCATCCTATTTGAAAAGCACA CTAGAAAATCAAAACCGTCCGT [SEQ ID NO:1293] [SEQ ID NO:1294] Lmo1133 TCAAACTACCGGCAAAGTTTCT AAATTCAACCGTGTCAAGTTCC [SEQ ID NO:1295] [SEQ ID NO:1296] Lmo1134 AAATTTCCCACAAAGCAAAT GTATCCGATTTGGGAGTGTT [SEQ ID NO:1297] [SEQ ID NO:1298] Lmo1135 AGTTCCGCTTGTTATTCGTA CAAACGATATCTCCCCATCT [SEQ ID NO:1299] [SEQ ID NO:1300] Lmo1136 AGTCATCCAGATGCCAAGAAAT ATGGATTGTCTATCTCAACCGC [SEQ ID NO:1301] [SEQ ID NO:1302] Lmo1188 AGGTTAGAGGTTGCACGAATGT ATTCGGACAAAAATTTGAATGG [SEQ ID NO:1303] [SEQ ID NO:1304] Lmo1247 ATGGAAAGGCCAGATAATCAAC AATCTCCTTGTTTGGTCATGCT [SEQ ID NO:1305] [SEQ ID NO:1306] Lmo1263 TGGCAAAAATAACAGGAAGTGT CACGAGCAACAAGCACATACTC [SEQ ID NO:1307] [SEQ ID NO:1308] Lmo1289 AGGTCACTGGTAATCGTCCC TCAGACTGTCAAATTACTAACTTC [SEQ ID NO:1309] [SEQ ID NO:1310] Lmo1302 TCGCATCCAGTTCTACTGTT TAAAGCCCGATTACTTTTCC [SEQ ID NO:1311] [SEQ ID NO:1312] Lmo1303 GATGCCCATGAACAGTAGAA AGCTAACAAAGTCCGCTTTC [SEQ ID NO:1313] [SEQ ID NO:1314] Lmo1307 ATCTTTCTTCCACGGATAGC TTGTTCAAAAAGGGCTGTTA [SEQ ID NO:1315] [SEQ ID NO:1316] Lmo1413 CACTTGCAACATCCGATACATT TCACTCGTGAAAACGCTACTGT [SEQ ID NO:1317] [SEQ ID NO:1318] Lmo1441 ATGTCGAAGCAACAGTAGCAGA AATTCCGAGATGCAGAGGATAA [SEQ ID NO:1319] [SEQ ID NO:1320] Lmo1451 AGTAGATGGCGCTAATCGAGAA CTTGGGCTAAACGAGCAGTATT [SEQ ID NO:1321] [SEQ ID NO:1322] Lmo1478 TTTGTCGATTTATACATTGCGTT TGACATAATTTCTCTCGGCAGT [SEQ ID NO:1323] [SEQ ID NO:1324] Lmo1597 GGTGGTGGTGAGTTGAATCTTA TGCAGTCACCTTAGCACCATTA [SEQ ID NO:1325] [SEQ ID NO:1326] Lmo1604 GGCAGAACGTTTAGTAGGCAC ACCGGGTTGCCAGTTAATC [SEQ ID NO:1327] [SEQ ID NO:1328] Lmo1648 GGTTTTGATCCTTGGGATAGTG TTTCAGGATTATTTCCCCACAT [SEQ ID NO:1329] [SEQ ID NO:1330] Lmo1656 GACAAGAATCGGACATTTCA CATCGCTTTTTCAGCTTTTA [SEQ ID NO:1331] [SEQ ID NO:1332] Lmo1666 TGTAGTTGATGTTGGAAGTCCG TATAATCGGCGCTACCGTATCT [SEQ ID NO:1333] [SEQ ID NO:1334] Lmo1700 GTCGTGCCATTATTATTCGCTT TCCAGTGCCAATTACCAATATG [SEQ ID NO:1335] [SEQ ID NO:1336] Lmo1707 ATGAATCTTGAAACCCCTTCG TGGATTTGCGTTTAATTAGCTG [SEQ ID NO:1337] [SEQ ID NO:1338] Lmo1714 CGTGCATTACGGTAAAGTTGGT CCTTCTTCTTCGCTGAAAAT [SEQ ID NO:1339] [SEQ ID NO:1340] Lmo1786 GGGAAGCAAAGTGTTACAGACC GATATCCATCTTCCATCTGGGT [SEQ ID NO:1341] [SEQ ID NO:1342] Lmo1799 ACAACAACGATGATGGTAGC CATCATTGGCACTAGGTAGC [SEQ ID NO:1343] [SEQ ID NO:1344] Lmo1968 GTGCAATCAGCCAACAAAATAA TTCAAATTCACAGGCATGAATC [SEQ ID NO:1345] [SEQ ID NO:1346] Lmo1969 ATGGCAATTATTCGGGATGTAG TTGATTGAGCATAGCCTTTGTG [SEQ ID NO:1347] [SEQ ID NO:1348] Lmo1970 AGTAACACGAGCTGTTGCAT AAATCACACGCACTCCTTTA [SEQ ID NO:1349] [SEQ ID NO:1350] Lmo1971 ACAGGAAATGATGAAGTCGGTT AATAATGGCTCCTCGTCTACCA [SEQ ID NO:1351] [SEQ ID NO:1352] Lmo1973 GGAGGTAGAAAGTCCGGTAG TCCAACTGTAAAGCCATGTT [SEQ ID NO:1353] [SEQ ID NO:1354] Lmo1974 TGACAGTTCGAAAAGCGATAGA ATAGGAAGTACGTCGCACATGA [SEQ ID NO:1355] [SEQ ID NO:1356] Lmo2026 TATGATGATGGGACTTCTGC ATTTGCTTTCATCCAATGTG [SEQ ID NO:1357] [SEQ ID NO:1358] Lmo2027 TGGTGGAGATCTAAAAGCAA TGGCACATCATCACTTGTAA [SEQ ID NO:1359] [SEQ ID NO:1360] Lmo2045 CCAGTTGTGGTATTTATTTTGACG AAAGCGCCACATACAATAAAGC [SEQ ID NO:1361] [SEQ ID NO:1362] Lmo2067 TACCGCTGTCTCCATTACATTG GTTGCTCATTGACGAGTGGATA [SEQ ID NO:1363] [SEQ ID NO:1364] Lmo2085 TTTAATGGGGATGGTATTCAGC ATTGATCCTGTTTTCTCAGCGT [SEQ ID NO:1365] [SEQ ID NO:1366] Lmo2143 GTAGTGTCGCTGGCTTTCTCTT AGTTGCTCCGTTGAAACTCAAT [SEQ ID NO:1367] [SEQ ID NO:1368] Lmo2144 GGAAAACCGGAGATAAAATTCC ATTGGTTCCTGCTTATCGATTG [SEQ ID NO:1369] [SEQ ID NO:1370] Lmo2157 GGAAAACCGGAGATAAAATTCC ATTGGTTCCTGCTTATCGATTG [SEQ ID NO:1371] [SEQ ID NO:1372] Lmo2178 GACGCCAGCTGGTTTTTATATC ATACGCGTGAATTCTCCAAGTT [SEQ ID NO:1373] [SEQ ID NO:1374] Lmo2197 AAAAATCAGACTGTTAGTTTAAGCA GTCAACATAACAAAAATGGAACT [SEQ ID NO:1375] [SEQ ID NO:1376] Lmo2276 TGTTCGTTCTGAAAATGGGAAT TTATCTTCCGCATCTCTACGTG [SEQ ID NO:1377] [SEQ ID NO:1378] Lmo2277 TGAAGCATCAGCGGAATATAGA GAGAGAATGTATGGCTCTTTGG [SEQ ID NO:1379] [SEQ ID NO:1380] Lmo2278 TCAAACAATGCGCTCTTATCAT ACCGGTTTTATGCTTTTCAGTG [SEQ ID NO:1381] [SEQ ID NO:1382] Lmo2282 CAGTACCGCAAATAGTACGG AAAGCCTCTTGGGTGAGTAG [SEQ ID NO:1383] [SEQ ID NO:1384] Lmo2283 TGAAAAATGGGATGATTACG TATTCAGTGACCACGGTTCT [SEQ ID NO:1385] [SEQ ID NO:1386] Lmo2296 ACACCAGAGGTTTTTAATGCGT GTCGGGATATTAACTTCTCCCC [SEQ ID NO:1387] [SEQ ID NO:1388] Lmo2301 TTCAAAACGTATGCAGGATGAC GTTGCAAAGCCAGAATCCTTAC [SEQ ID NO:1389] [SEQ ID NO:1390] Lmo2302 GCTGACTGGGTAAGTGGGTTAG TCACAGGCCCTTTATTTTTCTT [SEQ ID NO:1391] [SEQ ID NO:1392] Lmo2311 GTGCTTTTGAACGATTTGACAC TCAATTTCTTCCACCATTTCAA [SEQ ID NO:1393] [SEQ ID NO:1394] Lmo2312 GTTGTGGTAATGCGAAATGT AAATCTGCACCCCTTAAATC [SEQ ID NO:1395] [SEQ ID NO:1396] Lmo2313 TATTGGCAGTTTGCTGTTCT CCGCAAATGAATCTGTGTAT [SEQ ID NO:1397] [SEQ ID NO:1398] Lmo2318 AAAAATCTGCGGCTAATCCTTT GCTTTCTAGTACAAACGTGCCA [SEQ ID NO:1399] [SEQ ID NO:1400] Lmo2319 AATGGCGGAGGAATTAGACAC CTTCCTTCTTTTAGAGCGCTTG [SEQ ID NO:1401] [SEQ ID NO:1402] Lmo2322 ACGAAGGTTACGAGTCGAAGAG ATAGTGTGCGCCTCGGTATAAT [SEQ ID NO:1403] [SEQ ID NO:1404] Lmo2324 ACTTTGAGTAAAACCAATGGGC GTGGTTTTCATTAAGCCGTTTC [SEQ ID NO:1405] [SEQ ID NO:1406] Lmo2331 TGTGGCGGAACAGATAATACAA AATTTCGTCATACGTTTCACTGTT [SEQ ID NO:1407] [SEQ ID NO:1408] Lmo2387 GCGGCTTTAATTGGTATCGTAG GGGAATCGAATAATTTTGGACA [SEQ ID NO:1409] [SEQ ID NO:1410] Lmo2408 TCCTTTGCTAAGTTGTTGAGA TTCAATGGCATGAATTGTTT [SEQ ID NO:1411] [SEQ ID NO:1412] Lmo2409 TTTCAATGATTGCTGCTATTC GAAAAATGGTAAACCAGGAAA [SEQ ID NO:1413] [SEQ ID NO:1414] Lmo2410 ATTTGCCTCACTCCTTTATCCA TTTCCTGGTTTACCATTTTTCG [SEQ ID NO:1415] [SEQ ID NO:1416] Lmo2443 TTATTCCCTTGGATGTCTAGCG ATAAAATACTTGCTGACACCGC [SEQ ID NO:1417] [SEQ ID NO:1418] Lmo2451 AGGTAAAAGTGCTGGCTTATCC CTGTACAAAGTATGCCAGTGCAA [SEQ ID NO:1419] [SEQ ID NO:1420] Lmo2548 GAATTCATCCTGAGTACCGTCC GCAGTCGCATGTTTTTGTTTAC [SEQ ID NO:1421] [SEQ ID NO:1422] Lmo2567 ATCGCACTTAATATCGTACTTGATA GGAGAATTACCCCACATACGAT [SEQ ID NO:1423] [SEQ ID NO:1424] Lmo2576 TTAATACCGCCGGAAAATTATG GTTTCTGTATCCGAGGTCAAGG [SEQ ID NO:1425] [SEQ ID NO:1426] Lmo2594 TTTGTAACAGCATGCTCAACCT TATTTGGGCTGGTGAAGTTTCT [SEQ ID NO:1427] [SEQ ID NO:1428] Lmo2595 ACGGTGAAGCAACTATAGAGGG CGTACTTTCGTCGCCTAATTGT [SEQ ID NO:1429] [SEQ ID NO:1430] Lmo2671 CAAATATTTCCACACAAGATCCG CACTCAGCCACACAAGGTTCT [SEQ ID NO:1431] [SEQ ID NO:1432] Lmo2686 TAGCGCTTCCGAAATAGAGAAT CCCGCTTACTGATGCTTTTAAC [SEQ ID NO:1433] [SEQ ID NO:1434] Lmo2731 GGAATGGAGTATCAATTCGGAG TTTTGCGAAGTTGTGATAGTGG [SEQ ID NO:1435] [SEQ ID NO:1436] Lmo2732 TAAAGCTTTCCGGTTTCTCTGA GGGCATGATGATGTTTAAATGA [SEQ ID NO:1437] [SEQ ID NO:1438] Lmo2733 GAATGCCTTTTATCCAAAGACG AAATCCGGCAATGATACCTAAA [SEQ ID NO:1439] [SEQ ID NO:1440] Lmo2734 AACAAGCGCACTTAGAATGACA CATTTTCGAAGCGAATTAGGTC [SEQ ID NO:1441] [SEQ ID NO:1442] Lmo2735 AACATCTGGCACGACTTGTATG TAGTAAATCGCTGGGACACCTT [SEQ ID NO:1443] [SEQ ID NO:1444] Lmo2736 GCCAACACGATTGGATTAGATT TCGGCGTCTTTCATTTTATCTT [SEQ ID NO:1445] [SEQ ID NO:1446] Lmo2771 ATTAACAAATGAGGTGAACGGC CGAATTTTTATAGGCAGGATCG [SEQ ID NO:1447] [SEQ ID NO:1448] Lmo2772 TTGACGCTTGTTGTTATTGGAC CATTTGCTCATCAATACCGAAA [SEQ ID NO:1449] [SEQ ID NO:1450] Lmo2773 AAGGGGCTTGGCTTTAATTCTA CCAATAATTACGCGTTGACAGA [SEQ ID NO:1451] [SEQ ID NO:1452] Lmo2776 TAGCGATAGCATTGCTTACAGTG GCCCAATTAGCTTTATTACCCC [SEQ ID NO:1453] [SEQ ID NO:1454] Lmo2781 GAACCGAAGTCTGATTGGAGAC AATTACAGGCTTTGCAGTACGC [SEQ ID NO:1455] [SEQ ID NO:1456] Lmo2782 GCTGATGTGTAATGCAGGAATG CATACGGCCATAATCAACGATA [SEQ ID NO:1457] [SEQ ID NO:1458] Lmo2786 TGAAAACAAGGGTTTTTGGAGT TGCTTCGTAAGCTAATTCCCAT [SEQ ID NO:1459] [SEQ ID NO:1460] Lmo2787 TTTTAGGCTACACGAGTGCAAA CTTGCTGTAAATGACATTGGGA [SEQ ID NO:1461] [SEQ ID NO:1462] Lmo2807 GGAGTAAAATTCTATATGGATGAGA AGATACTTGCTCCTCCGCAC [SEQ ID NO:1463] [SEQ ID NO:1464] Lmo2809 TAATGATTGTTGCGGGATTAGG TTGTAAGACACAACTTGGGGTG [SEQ ID NO:1465] [SEQ ID NO:1466] Lmo2821 TGACGTCTTCTCCTTTGATGG TAGACTGCCAAGCCGCTGG [SEQ ID NO:1467] [SEQ ID NO:1468] rpoB (a) GCGGATGAAGAGGATAATTACG GGAATCCATAGATGGACCGTTA [SEQ ID NO:1469] [SEQ ID NO:1470] rpoC (d) AATCCGTCTTCACCCTCTTGTA CGAGGATTTTCTTCTTGAATGG [SEQ ID NO:1471] [SEQ ID NO:1472] dnaN (a) TTTCCATCGAAGCATTTATTCC ATTTCAATAGATTCGCTTGCGT [SEQ ID NO:1473] [SEQ ID NO:1474] gyrB (a) ATTCGTTCTTACGTGGAGCATT GGATTACGGGAAGAACAGTCAG [SEQ ID NO:1475] [SEQ ID NO:1476]

TABLE 8 Probes spotted on the membrane and primary hybridization datXa Gene Description Functional category L. monocytogenes EGDe genes Lmo0017 372aa/Unknown, similar to Bacillus anthracis CapA protein Cell wall (polyglutamate capsule biosynthesis) Lmo0036 341aa/Unknown, similar to ornithine carbamoyltransferase Metabolism of amino acids and related molecules Lmo0037 461aa/Unknown, similar to amino acid transporter Transport/binding proteins and lipoproteins Lmo0038 363aa/Unknown, conserved hypothetical protein unknown Lmo0039 313aa/carbamate kinase Metabolism of amino acids and related molecules Lmo0040 369aa/Unknown, conserved hypothetical protein Phage-related functions Lmo0041 259aa/Unknown, conserved hypothetical protein, Regulation hypothetical regulator Lmo0066 604aa/Unknwon, similar to toxin components miscellaneous Lmo0067 329aa/Unknown, similar to dinitrogenase reductase ADP- Protein modification ribosylation system Lmo0068 107aa/Unknwon unknown Lmo0069 97aa/Unknwon unknown Lmo0071 85aa/Unknwon unknown Lmo0072 67aa/Unknown, Hypothetical unknown Lmo0073 94aa/Unknwon unknown Lmo0074 149aa/Unknwon unknown Lmo0079 492aa/unknown unknown Lmo0080 132aa/Unknwon unknown Lmo0081 200aa/Unknwon unknown Lmo0082 108aa/Unknwon unknown Lmo0083 122aa/Unknown, similar to transcription regulator (merR Regulation family) Lmo0084 327aa/Unknwon, similar to oxidoreductases Specific pathways Lmo0094 186aa/Unknwon unknown Lmo0106 300aa/Unknown, similar to transcription regulator Regulation Lmo0110 371aa/Unknown, similar to lipase Metabolism of lipids Lmo0141 80aa/Unknwon unknown Lmo0143 58aa/Unknwon unknown Lmo0144 147aa/Unknwon unknown Lmo0146 68aa/Unknwon, hypothetical protein unknown Lmo0147 145aa/Unknwon unknown Lmo0151 135aa/Unknwon unknown Lmo0160 571aa/Unknown, putative peptidoglycan bound protein Cell surface proteins (LPXTG motif) Lmo0171 832aa/Unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0172 112aa/Unknown, similar to transposase C-terminal part Transposon and IS Lmo0175 415aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo0200 237aa/prfA: listeriolysin positive regulatory protein Regulation Lmo0201 317aa/plcA: phosphatidylinositol-specific phospholipase c virulence Lmo0202 529aa/hly virulence Lmo0203 510aa/mpl: Zinc metalloproteinase precursor virulence Lmo0204 639aa/actA: actin-assembly inducing protein precursor virulence Lmo0205 289aa/plcB: phospholipase C virulence Lmo0206 107aa/Unknwon unknown Lmo0252 128aa/Unknown, similar to repressor (penicilinase Regulation repressor) Lmo0253 346aa/Unknown, similar to penicillinase antirepressor Regulation Lmo0255 167aa/Unknown, similar to unknown protein unknown Lmo0257 392aa/Unknown, similar to unknown protein unknown Lmo0262 490aa/inlG cell surface proteins Lmo0263 548aa/inlH: internalin H cell surface proteins Lmo0264 499aa/inlE: internalin E cell surface proteins Lmo0304 421aa/Unknwon unknown Lmo0310 358aa/unknown unknown Lmo0311 206aa/Unknwon unknown Lmo0312 400aa/Unknown, similar to unknown proteins unknown Lmo0313 248aa/Unknown, conserved hypothetical protein unknown Lmo0320 399aa/Unknown, similar to surface protein (peptidoglycan cell surface proteins bound, LPXTG motif) Lmo0333 1778aa/Unknown, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0334 174aa/Unknwon unknown Lmo0338 126aa/Unknwon unknown Lmo0378 148aa/Unknown unknown Lmo0379 151aa/Unknwon unknown Lmo0380 209aa/Unknwon unknown Lmo0381 128aa/Unknwon unknown Lmo0409 821aa/inIF internalin, similar to surface protein cell surface proteins (peptidoglycan bound, LPXTG motif) Lmo0419 184aa/Unknown, similar to unknown protein unknown Lmo0433 800aa/inIA: Internalin A cell surface proteins Lmo0434 630aa/inIB: Internalin B cell surface proteins Lmo0440 167aa/Unknown unknown Lmo0444 926aa/Unknown, conserved hypothetical protein unknown Lmo0445 495aa/Unknown, similar to transcription regulator Regulation Lmo0446 329aa/Unknown, similar to penicillin acylase and to Detoxification conjugated bile acid hydrolase Lmo0447 462aa/Unknown, similar to glutamate decarboxylase Metabolism of amino acids and related molecules Lmo0448 483/unknown, similar to amino acid antiporter Transport/binding proteins and lipoproteins Lmo0459 512aa/Unknown, similar to transcription regulator (VirR Regulation from Streptococcus pyogenes) Lmo0460 689aa/Unknown, putative membrane associated lipoprotein cell surface proteins Lmo0461 157aa/Unknwon unknown Lmo0462 161aa/Unknwon unknown Lmo0463 101aa/putative peptidoglycan linked protein (LPXAG motif) cell surface proteins Lmo0466 567aa/Unknown unknown Lmo0467 107aa/Unknwon unknown Lmo0469 290aa/Unknwon unknown Lmo0470 209aa/Unknown, weakly similar to site-specific DNA- DNA restriction/modification and repair methyltransferase Lmo0471 336aa/Unknwon unknown Lmo0472 295aa/Unknwon unknown Lmo0473 361aa/Unknwon unknown Lmo0474 115aa/Unknwon unknown Lmo0476 325aa/Unknown, similar to oxetanocin A resistance protein Detoxification oxrB Lmo0477 125aa/Unknown, putative secreted protein unknown Lmo0478 125aa/Unknown, putative secreted protein unknown Lmo0492 302aa/Unknown, similar to transcriptional regulator (LysR Regulation family) Lmo0493 586aa/Unknown, similar to acylase Detoxification Lmo0497 502aa/Unknown, similar to sugar transferase Cell wall Lmo0514 605aa/Unknown, similar to internalin proteins, similar to cell surface proteins surface protein (peptidoglycan bound, LPXTG motif) Lmo0525 443aa/Unknwon unknown Lmo0549 673aa/Unknown, similar to internalin protein cell surface proteins Lmo0550 98aa/Unknown, pepdidoglycan bound protein (LPXTG cell surface proteins motif) Lmo0610 589aa/Unknown, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0630 676aa/Unknown, similar to transcription antiterminator Regulation BgIG family Lmo0631 150aa/Unknown, similar to PTS system, fructose-specific Transport/binding proteins and lipoproteins IIA component Lmo0632 353aa/Unknown, similar to PTS system, fructose-specific Transport/binding proteins and lipoproteins IIC component Lmo0633 102aa/Unknown, similar to PTS system, fructose-specific Transport/binding proteins and lipoproteins IIB component Lmo0634 422aa/unknown, similar to an E. coli putative tagatose 6- Specific pathways phosphate kinase Lmo0638 209aa/Unknown unknown Lmo0673 69aa/Unknwon unknown Lmo0732 638aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo0733 169aa/Unknown, similar to transcription regulator Regulation Lmo0734 334aa/Unknown, similar to transcriptional regulator (Lacl Regulation family) Lmo0735 223aa/Unknown, similar to Ribulose-5-Phosphate 3- Specific pathways Epimerase Lmo0736 148aa/Unknown, similar to ribose 5-phosphate isomerase Specific pathways Lmo0737 310aa/Unknwon unknown Lmo0738 617aa/Unknown, similar to phosphotransferase system Transport/binding proteins and lipoproteins (PTS) beta-glucoside-specific enzyme IIABC component Lmo0739 457aa/Unknown, similar to 6-phospho-beta-glucosidase Specific pathways Lmo0745 167aa/Unknwon unknown Lmo0750 171aa/Unknwon unknown Lmo0751 98aa/Unknwon unknown Lmo0752 278aa/Unknown, weakly similar to a putative haloacetate Detoxification dehalogenase Lmo0753 226aa/unknown, similar to transcription regulator Crp/Fnr Regulation family Lmo0754 203aa/Unknown, weakly similar to a bile acid 7-alpha Detoxification dehydratase Lmo0780 115aa/Unknown unknown Lmo0801 646aa/Unknown, similar to internalin, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0804 156aa/Unknwon unknown Lmo0832 94aa/unknown, similar to transposase Transposon and IS Lmo0833 296aa/Unknown; similar to transcriptional regulator Regulation Lmo0834 237aa/Unknwon unknown Lmo0835 334aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo0838 461aa/unknown, highly similar to hexose phosphate Transport/binding proteins and lipoproteins transport protein Lmo0842 2044aa/Unknown, surface protein (LPXTG motif) cell surface proteins Lmo0843 85aa/unknown, similar to B. subtilis protein YsdA unknown Lmo0849 616aa/Unknown, similar to amidases Cell wall Lmo0880 462aa/Unknown, similar to wall associated protein cell surface proteins precursor (LPXTG motif) Lmo0932 201aa/unknown, conserved hypothetical protein unknown Lmo0933 315aa/unknown, similar to sugar transferase Cell wall Lmo1030 342aa/unknown, similar to transcriptional regulator, Lacl Regulation family Lmo1031 467aa/unknown, similar to hypothetical proteins unknown Lmo1032 274aa/unknown, similar to transketolase Specific pathways Lmo1033 318aa/unknown, similar to transketolase Specific pathways Lmo1034 487aa/unknown, similar to glycerol kinase Specific pathways Lmo1035 618aa/unknown, similar to phosphotransferase system Transport/binding proteins and lipoproteins (PTS) beta-glucoside-specific enzyme IIABC Lmo1036 421aa/Unknwon unknown Lmo1060 220aa/unknown, similar to transcription response regulator Regulation Lmo1061 481aa/unknown, similar to sensor protein histidine kinases Sensors (signal transduction) (2 components regulatory systems) Lmo1062 473aa/unknown, unknown, similar to ABC transporters Transport/binding proteins and lipoproteins (permease protein) Lmo1063 222aa/unknown, similar to ABC transporter (ATP binding Transport/binding proteins and lipoproteins protein) Lmo1076 572aa/unknown, similar to AUTOLYSIN (EC 3.5.28) (N- Cell wall ACETYLMURAMOYL-L-ALANINE AMIDASE) Lmo1077 562aa/unknown, similar to teichoic acid biosynthesis Cell wall protein B Lmo1079 952aa/unknown, similar to B. subtilis YfhO protein unknown Lmo1080 623aa/unknown, similar to B. subtilis minor teichoic acids Cell wall biosynthesis protein GgaB Lmo1081 288aa/Unknown, similar to glucose-1-phosphate thymidyl Cell wall transferase Lmo1082 186aa/Unknown, similar to dTDP-sugar epimerase Cell wall Lmo1083 328aa/Unknown, similar to dTDP-D-glucose 4,6-dehydratase Cell wall Lmo1084 276aa/unknown, similar to DTDP-L-rhamnose synthetase Cell wall Lmo1085 696aa/unknown, similar to teichoic acid biosynthesis Cell wall protein B Lmo1088 386aa/tagB: unknown, similar to teichoic acid Cell wall biosynthesis protein B precursor Lmo1090 327aa/unknown, similar to glycosyltransferases Cell wall Lmo1091 337aa/unknown, similar to glysosyltransferases Cell wall Lmo1097 400aa/unknown, similar to integrases Transposon and IS Lmo1099 139aa/unknown, similar to a protein encoded by Tn916 Transposon and IS Lmo1101 166aa/Unknown, similar to lipoprotein signal peptidase Protein secretion Lmo1102 111aa/unknown, similar to cadmium efflux system Detoxification accessory proteins Lmo1103 305aa/unknown, highly similar to TN916 ORF13 Transposon and IS Lmo1104 336aa/unknown, highly similar to TN916 ORF14 and to Cell wall L. monocytogenes P60 protein Lmo1105 719aa/unknown, highly similar to TN916 ORF15 Transposon and IS Lmo1106 816aa/unknown, highly similar to TN916 ORF16 Transposon and IS Lmo1107 131aa/unknown, highly similar to TN916 ORF17 Transposon and IS Lmo1108 166aa/unknown, highly similar to TN916 ORF18 Transposon and IS Lmo1110 96aa/unknown, similar to unknown proteins unknown Lmo1111 394aa/unknown, highly similar to TN916 ORF20 Transposon and IS Lmo1112 466aa/unknown, highly similar to TN916 ORF21 Transposon and IS Lmo1113 124aa/unknown, highly similar to TN916 ORF22 Transposon and IS Lmo1114 104aa/unknown, highly similar to TN916 ORF23 Transposon and IS Lmo1115 862aa/unknown, similar to fibrinogen-binding protein cell surface proteins (LPXTG motif) Lmo1116 257aa/unknown, similar to regulatory proteins Regulation Lmo1117 118aa/Uknwon unknown Lmo1118 505aa/Unknwon unknown Lmo1119 285aa/unknown, similar to methylases DNA restriction/modification and repair Lmo1120 138aa/Unknwon unknown Lmo1121 122aa/Unknwon unknown Lmo1125 177aa/unknown unknown Lmo1133 102aa/unknown, similar to B. subtilis YjcS protein unknown Lmo1134 115aa/unknown, similar to regulatory proteins Regulation Lmo1135 383aa/Unknwon unknown Lmo1136 539aa/Unknown, similar to internalin, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo1247 87aa/Unknwon unknown Lmo1263 71aa/unknown, similar to transcriptional regulator Regulation Lmo1289 593aa/Unknown, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo1302 204aa/unknown, highly similar to SOS response regulator Regulation lexA, transcription repressor protein Lmo1303 109aa/unknown, similar to B. subtilis YneA protein unknown Lmo1307 280aa/Unknwon unknown Lmo1413 439aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo1441 368aa/Unknown, similar to putative peptidoglycan Cell wall acetylation protein Lmo1451 331aa/Unknown, similar to E. coli LytB protein unknown Lmo1478 145aa/Unknown, similar to transcriptional regulator (MerR Regulation family) Lmo1597 259aa/Unknwon unknown Lmo1604 181aa/unknown unknown Lmo1648 120aa/Unknwon unknown Lmo1656 143aa/Unknwon unknown Lmo1666 1711aa/unknown, peptidoglycan linked protein (LPxTG) cell surface proteins Lmo1700 68aa/Unknwon unknown Lmo1707 73aa/Unknwon unknown Lmo1714 190aa/Unknwon unknown Lmo1786 296aa/inIC cell surface proteins Lmo1799 903aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo1968 247aa/unknown, similar to creatinine amidohydrolases Metabolism of amino acids and related molecules Lmo1969 202aa/Unknown, similar to 2-keto-3-deoxygluconate-6- Specific pathways phosphate aidolase Lmo1970 305aa/Unknown, similar to putative phosphotriesterase Metabolism of lipids related proteins Lmo1971 422aa, Unknown, similar to pentitol PTS system enzyme II C Transport/binding proteins and lipoproteins component Lmo1973 147aa/Unknown, similar to PTS system enzyme II A Transport/binding proteins and lipoproteins component Lmo1974 249aa/unknown, similar to transcription regulators, (GntR Regulation family) Lmo2026 626aa/unknown, peptidoglycan linked protein (LPxTG) cell surface proteins Lmo2027 367aa/Unknown, putative cell surface protein, similar to cell surface proteins internalin proteins Lmo2045 128aa/Unknwon unknown Lmo2067 325aa/Unknown, similar to conjugated bile acid hydrolase Detoxification Lmo2085 562aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo2143 580aa/Unknown, weakly similar to mannose-6-phosphate Specific pathways isomerase Lmo2144 244aa/Unknown, similar to transcription regulator GntR Regulation family Lmo2157 633aa/SepA-Unknown unknown Lmo2178 1612aa/Unknown, putative peptidoglycan bound protein cell surface proteins (LPXTG motif) Lmo2197 114aa/Unknwon unknown Lmo2276 165aa/Unknown, similar to an unknown bacteriophage Phage-related functions protein Lmo2277 183aa/Unknwon unknown Lmo2278 281aa/LysA: L-alanoyl-D-glutamate peptidase Phage-related functions Lmo2282 105aa/protein gp21 [Bacteriophage A118] Phage-related functions Lmo2283 357aa/protein gp20 [Bacteriophage A118] Phage-related functions Lmo2296 333aa/Unknown, similar to coat protein [Bacteriophage Phage-related functions SPP1] Lmo2301 264aa/Unknown, similar to putative terminase small subunit Phage-related functions from Bacteriophage A118 Lmo2302 179aa/unknown unknown Lmo2311 153aa/Unknwon unknown Lmo2312 156aa/Unknwon unknown Lmo2313 147aa/Unknown, similar to a bacteriophage protein Phage-related functions Lmo2318 232aa/Unknwon unknown Lmo2319 158aa/Unknown, similar to bacteriophage proteins Phage-related functions Lmo2322 71aa/gp44 [Bacteriophage A118] Phage-related functions Lmo2324 258aa/Unknown, similar to anti-repressor [Bacteriophage Regulation A118] Lmo2331 226aa/Unknown, weakly similar to gp32_Bacteriophage Phage-related functions A118 protein Lmo2387 408aa/Unknown, conserved hypothetical protein unknown Lmo2408 67aa/Unknown, similar to repressor protein Regulation Lmo2409 137aa/Unknwon unknown Lmo2410 183aa/unknown unknown Lmo2443 139aa/Unknwon unknown Lmo2451 77aa/Unknown, similar to preprotein translocase subunit Protein secretion SecG Lmo2548 81aa/rpmE: ribosomal protein L31 Ribosomal proteins Lmo2567 66aa/Unknwon unknown Lmo2576 1530aa/Unknwon, peptidoglycan anchored protein (LPXTG cell surface proteins motif) Lmo2594 119aa/Unknwon unknown Lmo2595 289aa/Unknown, similar to unknown proteins unknown Lmo2671 122aa/Unknwon unknown Lmo2686 177aa/Unknwon unknown Lmo2731 122aa/unknown, similar to transcription regulator (RpiR Regulation family) Lmo2732 250aa/Unknwon unknown Lmo2733 652aa/Unknown, similar to PTS system, fructose-specific Transport/binding proteins and lipoproteins IIABC component Lmo2734 882aa/Unknown, weakly similar to sugar hydrolase Specific pathways Lmo2735 560aa/Unknown, similar to Sucrose phosphorylase Specific pathways Lmo2736 377aa/Unknown, conserved hypothetical protein unknown Lmo2771 482aa/Unknown, similar to beta-glucosidase Specific pathways Lmo2772 617aa/Unknown, similar to beta-glucoside-specific enzyme Transport/binding proteins and lipoproteins IIABC Lmo2773 279aa/Unknwon, similar to transcription antiterminator Regulation Lmo2776 131aa/Unknwon unknown Lmo2781 756aa/Unknown, similar to beta-glucosidase Specific pathways Lmo2782 99aa/Unknown, similar to PTS, cellobiose-specific IIB Transport/binding proteins and lipoproteins component Lmo2786 327aa/bvrC: unknown unknown Lmo2787 640aa/bvrB-beta-glucoside-specific phosphotransferase Transport/binding proteins and lipoproteins enzyme II Lmo2807 127aa/Unknown, hypothetical secreted protein unknown Lmo2809 126aa/Unknown, hypothetical secreted protein unknown Lmo2821 851aa/Unknown, similar to internalin, Unknown, putative Cell surface proteins peptidoglycan bound protein (LPXTG motif) L. innocua (CLIP11262) genes Lin0035 219aa/Unknown, similar to E. coli DedA protein unknown Lin0038 179aa/unknown, highly similar to single-strand binding DNA replication protein (SSB) Lin0060 204aa/unknown unknown Lin0062 210aa/unknown, hypothetical protein unknown Lin0064 129aa/Unknwon unknown Lin0065 136aa/Unknwon unknown Lin0072 216aa/Unknwon unknown Lin0073 158aa/Unknown, similar to a putative repressor protein Regulation [Bacteriophage A118] Lin0197 358aa/unknown, similar to chloromuconate cycloisomerase Metabolism of carbohydrates (Specific ykfB of B. subtilis pathways) Lin0198 292aa/unknown, P45 related protein Cell wall Lin0199 257aa/unknown, some similarities to probable beta-lactamase Detoxification Lin0307 219aa/unknown, similar to ABC transporters (ATP-binding Transport/binding proteins and lipoproteins protein) Lin0308 261aa/unknown, similar to hypothetical proteins unknown Lin0332 405aa/unknown, similar to putative permeases Transport/binding proteins and lipoproteins Lin0338 266aa/Unknwon unknown Lin0372 656aa/unknown, probable cell surface protein (LPXTG motif) cell surface proteins Lin0397 120aa/Unknwon unknown Lin0398 536aa/Unknwon unknown Lin0399 252aa/Unknwon unknown Lin0415 410aa/unknown, probable cell surface protein (LPXTG motif) cell surface proteins Lin0453 169aa/unknown unknown Lin0454 2167aa/unknown, similar to cell wall-associated protein cell surface proteins precursor wapA (B. subtilis) Lin0455 184aa/Unknwon unknown Lin0465 212aa/unknown, conserved hypothetical protein, similar to unknown yoaZ B. subtilis Lin0476 350aa/Unknwon unknown Lin0478 407aa/Unknwon unknown Lin0559 96aa/unknown, probable cell surface protein (LPXTG motif) cell surface proteins Lin0661 596aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0665 831aa/unknown, highly similar to ORFA of Listeria seeligeri, cell surface proteins (LPXTG motif) Lin0677 293aa/unknown, conserved hypothetical protein unknown Lin0739 521aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0740 657aa/unknown, probable cell surface protein (LPXTG motif) Cell surface proteins Lin0772 417aa/Unknwon unknown Lin0801 240aa/unknown, similar to two-component response RNA synthesis (Regulation) regulators Lin0802 433aa/unknown, similar to two-component sensor histidine Sensors (signal transduction) kinases Lin0803 1386Unknown, surface protein (LPXTG motif) cell surface proteins Lin0833 489aa/Unknwon unknown Lin0834 369aa/unknown, some similarities to hypothetical proteins unknown Lin0835 285aa/Unknwon unknown Lin0865 131aa/unknown, hypothetical protein unknown Lin0867 421aa/Unknwon unknown Lin0868 378aa/Unknwon unknown Lin1065 668aa/unknown, hypothetical protein unknown Lin1066 329aa/unknown, similar to dolichol phosphate mannose synthase Cell wall Lin1067 696aa/unknown unknown Lin1067 774aa/unknown, similar to hypothetical protein 3 (capsulation Cell wall locus) of Haemophilus influenzae Lin1068 Lin1069 336aa/Unknwon unknown Lin1073 462aa/unknown, similar to galactosamine-containing minor Cell wall teichoic acid biosynthesis protein GgaA Lin1082 387aa/Unknwon unknown Lin1083 216aa/Unknwon unknown Lin1084 94aa/Unknwon unknown Lin1090 111aa/Unknwon unknown Lin1099 235aa/Unknwon unknown Lin1204 1237aa/unknown, similar to internalin proteins (LPXTG motif) Cell surface proteins Lin1211 486aa/unknown unknown Lin1212 184aa/Unknwon unknown Lin1241 Lin1258-57 184aa-175aa/Unknown unknown Lin1260 255aa/unknown, similar to probable antirepressor - Bacillus Phage-related functions subtilis phage SPBc2 Lin1262 445aa/Unknwon unknown Lin1299 121aa/Unknwon unknown Lin1300 203aa/Unknwon unknown Lin1328 620aa/unknown, internalin like protein (LPXTG motif) Cell surface proteins Lin1452 125aa/Unknwon unknown Lin1621 253aa/unknown, similar to ketoacyl reductases Metabolism of lipids Lin1723 199aa/Unknwon unknown Lin1728 369aa/unknown, similar to hypothetical proteins unknown Lin1731 461aa/unknown, some similarities to conserved hypothetical unknown proteins Lin1744 453aa/Unknwon unknown Lin1745 140aa/Unknown unknown Lin1747 125aa/Unknwon unknown Lin1756 660aa/unknown, similar to hypothetical protein of unknown Staphylococcus aureus phage phi PVL Lin1811 323aa/unknown, similar to unknown proteins unknown Lin1813 620aa/Unknown, similar to excinuclease ABC subunit A DNA restriction/modification and repair Lin1898 177aa/Unknown, similar to putative NAD(P)H oxidoreductase Membrane bioenergetics (electron transport chain and ATP synthase) Lin2100 764aa/unknown, similar to p60-related proteins Cell wall Lin2373 298aa/Unknown, similar to AbiD phage protein Phage-related functions Lin2383 1601unknown, similar to hypothetical protein [Lactobacillus Phage-related functions casei bacteriophage A2] Lin2394 439aa/Unknown unknown Lin2397 190aa/unknown, similar to sigma factor-like positive control RNA synthesis (Initiation) protein of B. subtilis Lin2405 69aa/Unknwon unknown Lin2425 235aa/Unknwon unknown Lin2494 124aa/unknown, hypothetical protein unknown Lin2603 95aa/Unknwon unknown Lin2604 80aa/Unknwon unknown Lin2693 497aa/Unknwon unknown Lin2724 938aa/unknown, internalin-like protein (LPXTG motif) cell surface proteins Lin2741 152aa/Unknwon unknown Lin2743 98aa/Unknwon unknown Lin2744 1334aa/unknown, similar to hypothetical proteins unknown Lin2839 99aa/Unknwon unknown Lin2918 159aa/Unknwon unknown Lin2941 663aa/Unknwon unknown Lin2945 191aa/Unknwon unknown L. monocytogenes (CLIP 80459) genes ORF 2541 590bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 2017 285bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 3401 575bp/unknown unknown ORF 2074 599bp/unknown similar to oligo-1,6-glucosidase Specific pathways ORF 528-529 591bp/unknown-unknown unknown ORF 2815 603bp/unknown, similar to heat shock protein HtpG unknown ORF 2568-2569 597bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif)-unknown ORF 2847 590bp/similar to phage integrase Phage-related functions ORF 1388-1387 600bp/unknown-unknown unknown ORF 799 453bp/unknown unknown ORF 72-73-74 598bp/unknown-unknown-unknown unknown ORF 1912-1913 602bp/unknown-unknown unknown ORF 150 393bp/unknown, similar to amidase cell wall ORF 2777 600bp/unknown unknown ORF 2579 601bp/unknown, sucrose phosphorylase Specific pathways ORF 75 504bp/unknown unknown ORF 660 603bp/unknown unknown ORF 2884-2885 592bp/unknown unknown ORF 2885 592bp/unknown unknown ORF 1445 607bp/unknown, conserved hypothetical protein ykcB - unknown Bacillus subtilis ORF 1590 588bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 182 468bp/unknown, similar to B. subtilis YukA, unknown ORF 1761 599bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 105 599bp/unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 2372 596bp/unknown, similar to teichoic acid biosynthesis cell wall protein C ORF 2110 597bp/unknown, similar to hypothetical protein unknown ORF 1491 598bp/unknown, similar to hypothetical protein unknown ORF 1490 600bp/unknown, similar to sucrose-specific PTS system Transport/binding proteins IIBC component and lipoproteins ORF 1390 624bp/unknown, similar to hypothetical protein unknown ORF 1391 600bp/unknown unknown ORF 1228 599bp/unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 29 609bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 3792 594bp/unknown unknown ORF 3840 593bp/unknown, similar to transcription regulator Regulation ORF 4101 613bp/unknown, similar to similar to ABC transporter Transport/binding proteins and lipoproteins ORF 3103 600bp/unknown, similar to peptidoglycan lytic protein P45 cell wall ORF 1490 474bp/unknown, similar to sucrose phosphotransferase Transport/binding proteins enzyme IIBC component and lipoproteins ORF 2217 602bp/unknown, imilar to type II DNA modification enzyme DNA restriction/modification and repair ORF 2939-2968 583bp/unknown-unknown unknown ORF 4457 588bp/unknown, DNA double-strand break repair rad50 DNA ATPase restriction/modification and repair ORF 3184 597bp/unknown unknown ORF 148-149 620bp/unknown-unknown, similar to amidase cell wall ORF 3157 589bp/unknown, similar to phage protein Phage-related functions ORF 2858 249bp/unknown, similar to hypothetical protein unknown ORF 1384-1385 422bp/unknown-unknown unknown ORF 2541 351bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 2819 562bp/unknown, similar to transcriptional regulator Regulation ORF 2262 601bp/unknown unknown ORF 817 594bp/unknown unknown ORF 757 522bp/unknown unknown ORF 2013 595bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) ORF 2076 597bp/unknown, similar to maltodextrin ABC transporter Transport/binding proteins and lipoproteins ORF 2013 597bp/unknwon, similar to internalin proteins, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) dnaN (a) 381aa/DNA polymerase III, beta chain DNA replication dnaN (b) dnaN (c) 381aa/DNA polymerase III, beta chain DNA replication dnaN (d) gyrB (a) 646aa/DNA gyrase subunit B DNA packaging and segregation gyrB (b) gyrB (c) 646aa/DNA gyrase subunit B DNA packaging and segregation gyrB (d) rpoB (a) 1184aa/RNA polymerase (beta subunit) Elongation rpoB (b) rpoB (c) 1184aa/RNA polymerase (beta subunit) Elongation rpoB (d) rpoC (a) 1201aa/RNA polymerase (beta subunit) Elongation rpoC (b) rpoC (c) 1201aa/RNA polymerase (beta subunit) Elongation rpoC (d)

TABLE 9 L. monocytogenes specific marker genes L. monocytogenes 1/2a, 1/2b, 1/2c, L. ivanovii, L. innocua, 3a, 3b, 3c, 7, 4b, L. welshimeri, L seeligeri 4d, 4e 4c 4a L. grayi Gene name (88 strains) (2 strains) (3 strains) (20 strains) Functional category I Lmo 0082 88 2 3 0 Unknown Lmo 0083 88 2 3 0 Regulation plcA 88 2 3 0 Virulence actA 88 2 3 0 Virulence plcB 88 2 3 0 Virulence Lmo206 88 2 3 0 Unknown inlA 88 2 3 0 Cell surface proteins inlB 88 2 3 0 Cell surface proteins Lmo 0440 88 2 3 0 Unknown Lmo 0638 88 2 3 0 Unknown Lmo 0733 88 2 3 0 Regulation Lmo 0833 88 2 3 0 Regulation Lmo 1133 88 2 3 0 Unknown Lmo 1135 88 2 3 0 Unknown Lmo 2732 88 2 3 0 Unknown Lmo 2733 88 2 3 0 Transport/binding proteins and lipoproteins Lmo 2734 88 2 3 0 Specific pathways Lmo 2736 88 2 3 0 Unknown II Lmo0017 88 2 0 0 Cell wall Lmo0094 88 0 0 0 Unknown inlH 88 2 0 0 Cell surface proteins inlE 88 2 0 0 Cell surface proteins Lmo0333 88 2 0 0 Cell surface proteins Lmo0549 88 2 0 0 Soluble internalins Lmo0832 88 0 0 0 Transposon and IS Lmo0834 88 2 0 0 Unknown Lmo0835 88 0 0 0 Cell surface proteins Lmo1441 88 0 0 0 Cell wall Lmo1451 88 0 0 0 Unknown Lmo2821 88 2 0 0 Cell surface proteins

TABLE 10 L. monocytogenes lineage specific marker genes Lineage I Lineage II Lineage III I. 2 II. 1 III. 2 I. 1 (1/2c, 3c) (4b, 4d, 4e) II. 2 III. 1 (4c) Gene (1/2a, 3a) (12 (27 (1/2b, 3b) (4a) (2 name (27strains) strains) strains) (20strains) (3 strains) strains) Functional category A Lmo 0171 27 12 0 0 0 0 Cell surface proteins Lmo 0172 27 12 0 0 0 0 Transposon and IS Lmo 0525 27 12 0 0 0 0 Unknown Lmo 0734 27 12 0 0 0 0 Regulation Lmo 0735 27 12 0 0 0 0 Specific pathways Lmo 0736 27 12 0 0 0 0 Specific pathways Lmo 0737 27 12 0 0 0 0 Unknown Lmo 0738 27 12 0 0 0 0 Transport/binding proteins and lipoproteins Lmo 0739 27 12 0 0 0 0 Specific pathways Lmo 1060 27 12 0 0 0 0 Regulation Lmo 1061 27 12 0 0 0 0 Sensors Lmo 1062 27 12 0 0 0 0 Transport/binding proteins and lipoproteins Lmo 1063 27 12 0 0 0 0 Transport/binding proteins and lipoproteins Lmo 1968 27 12 0 0 0 0 Metabolism of amino acids Lmo 1969 27 12 0 0 0 0 Specific pathways Lmo 1970 27 12 0 0 0 0 Metabolism of lipids Lmo 1971 27 12 0 0 0 0 Transport/binding proteins and lipoproteins Lmo 1973 27 12 0 0 0 0 Transport/binding proteins and lipoproteins Lmo 1974 27 12 0 0 0 0 Regulation bvrC 27 12 0 0 0 2 Unknown bvrB 27 12 0 0 0 2 Transport/binding proteins and lipoproteins B Lmo 0151 3 12 0 0 0 0 Unknown Lmo 0466 2 12 0 0 0 0 Unknown Lmo 0467 2 12 0 0 0 0 Unknown Lmo 0469 2 12 0 0 0 0 Unknown Lmo 0470 2 12 0 0 0 0 DNA restrictions and modifications Lmo 0471 2 12 0 0 0 0 Unknown Lmo 1118 1 12 0 0 0 0 Unknown Lmo 1119 1 12 0 0 0 0 DNA restrictions and modifications C ORF2819 0 0 27 20 0 0 Unknown, Similar to hypothetical transcriptional regulator ORF3840 0 0 27 20 0 0 Unknown, similar to transcriptional regulator ORF2568 0 0 27 20 0 0 Unknown, Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG) ORF1761 0 0 27 20 0 0 Unknown, Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG) ORF0029 0 0 27 19 0 0 Unknown, Similar to internalin proteins, putative peptidoglycan bound protein (LPXTG) D ORF0799 0 0 27 0 0 0 Unknown ORF2372 0 0 27 0 0 0 Unknown, Similar to teichoic acid protein precurser C ORF2110 0 0 27 0 0 0 Unknown, Putative secreted protein

TABLE 11 Distribution of cell surface proteins L. monocytogenes Lineage I Lineage II Lineage III I.1 I.2 II.1 II.2 III.1 III.2 (1/2a,3a) (1/2c,3c) (4b,4d,4e) (1/2b,3b, (4c) (4a) L. L. L. L. L. (27 (12 (27 7)(20 (2 (3 innocua ivanovii seeligeri welshimeri grayi Gene strains) strains) strains) strains) strains) strains) (8 strains) (6 strains) (2 strains) (2 strains) (2 strains) inlA

− − − − − inlB

− − − − − Lmo2085

− − +/− +/− − Lmo1413

− − +/− − − Lmo0463

− − − − − Lmo0460

− − − − − Lmo0550

−* − − − − Lmo0160

−* − − − − Lmo0333

− − − − − − inlE

− − − − − − inlH

− − − − − − Lmo2821

− − − − − − Lmo2027

− − − − − − inlC

− − + − − − Lmo0835

− − − − − − − Lmo1666

− − − − +/− − − inlF

− − − − − − − Lmo320

− −* − − − − − Lmo0842

− −* +* −* − + − Lmo0801

−* −* − −* −* − +/− +/− − inlG

−* −

− − − − − − Lmo1115

−* −*

−* −* −* +/− − − Lmo2576

− −

− − − − − − Lmo0171

− − − − − − − − − Lmo2026

− − − − − − − − − Lmo2178 + + + + + + + −* − + − Lmo1799 + + + + + + +* + +/− + − Lmo1289 + + + + + + +* +* + +/− − Lmo1136 + + + + + + + + + + + Lmo0880 + + + + + + +* +* + + − Lmo0514 + + + + + + +* +* + + − Lmo0175 + + + + + + + − − − − Lmo0732 + + +* +* + + +* +/− − +/− − Lmo0610 + + + +* + +* +/− −* − − − Lin0739 − − − − − −

− − − − Lin0803 − − − − − −

− − − − Lin0559 −* − −* −* − − + − − − − Lin2724 − − − − +/− + + −* − − − Lin1204 − − + +* − + +* − − − − Lin0372 +* +* + + + + + − − − − Lin0415 +* +* +* +* + − + − +/− + − Lin0665 +* +* + + + + + − + +/− − Lin0740 +* +* +* +* + +* + − − − − Lin0661 +* +* −* −* + − + − − − − Lin1328 +* +* +* +* + +* + +* +/− − − ORF2568 − −

− − − +/− − − − ORF1761 − −

− − − − − − − ORF0029 − −

− − − − − − − ORF1590 + − + +* + − − − − − − ORF2541 −* − + + − − − − − − − ORF2013 −* − + +* + − − − − − − ORF2017 +* − + + + − −* +/− − − − + or − : indicates gene presence or absence in all strains of the corresponding serovar +* or −* : indicates gene presence or absence in at least two thirds of the strains of the corresponding serovar. +/− was used when the gene is present in one of two strains studied; Lmo and Lin numbers are corresponding to gene names on the ListiList web server http://genolist.pasteur.fr/ListiList/. Serovar and total number of strains studied for each lineage are indicated between brackets. Shaded boxes indicate species or lineage specific genes.

TABLE 12 Product size Gene Accession targets Primer sequence (5′-3′) (bp) Lmo0737 For: AGGGCTTCAAGGACTTACCC 691 [SEQ ID NO:1477] Rev: ACGATTTCTGCTTGCCATTC [SEQ ID NO:1478] Lmo1119 For: ATCCTGGTGGTAAACATAAAATG 782 [SEQ ID NO:1479] Rev: TGAGAAGAATAAAAATTCAGCACCT [SEQ ID NO:1480] ORF2819 For: AGCAAAATGCCAAAACTCGT 471 [SEQ ID NO:1481] Rev: CATCACTAAAGCCTCCCATTG [SEQ ID NO:1482] ORF2110 For: AGTGGACAATTGATTGGTGAA 600 [SEQ ID NO:1483] Rev: CATCCATCCCTTACTTTGGAC [SEQ ID NO:1484] prs For: GCTGAAGAGATTGCGAAAGAAG 348 [SEQ ID NO:1485] Rev: CAAAGAAACCTTGGATTTGCGG [SEQ ID NO:1486]

TABLE 13 Total number Multiplex PCR Percentage Conventional of Multiplex PCR results serovar of serotyping Origin strains 348pb 691 bp 471 pb 782 pb 600 pb interpretation agreements 1/2a Human 20 + + − − − 1/2a or 3a 100 Food 20 + + − − − 1/2b Human 20 + − + − − 1/2b, 3b or 7 100 Food 20 + − + − − 1/2c Human 20 + + − + − 1/2c or 3c 100 Food 20 + + − + − 4b Human 20 + − + − + 4b, 4d or 4e 100 Food 20 + − + − +

TABLE 14 Oligonucleotide primers for L. monocytogenes specific marker genes Gene Forward (5′ to 3′) Reverse (5′ to 3′) I Lmo 0082 CCAACAGGAGCTAACATGAA TGGTTAGGAAGATTGGGATT [SEQ ID NO:1487] [SEQ ID NO:1488] Lmo 0083 GAAGGCTTAATAACCCCTGAC CGCAACCTTCTCCTCATAAAT C [SEQ ID NO:1489] C [SEQ ID NO:1490] plcA CTGACACAACAAACCTAGCAG TGAATTTTGTTTTCACACTCG C [SEQ ID NO:1491] G [SEQ ID NO:1492] actA GAGGTAAATGCTTCGGACTT AGGCGATCAATTTCTTCTTC [SEQ ID NO:1493] [SEQ ID NO:1494] plcB GTATGTGCTTGATCGCAAGTG AAAATTATTGGCGTGCATAGG T [SEQ ID NO:1495] T [SEQ ID NO:1496] Lmo206 TTAGTAATCGCGTTATGTTCC AGCAACTTTTTGTTCGTCTTC G [SEQ ID NO:1497] A [SEQ ID NO:1498] inlA TAACATCAGTCCCCTAGCAGG TCCAATAGTGACAGGTTGGCT T [SEQ ID NO:1499] A [SEQ ID NO:1500] inlB AAAAGCAAGATTTCATGGGAG TCTCACTCTTGCATAAGCGGT A [SEQ ID NO:1501] A [SEQ ID NO:1502] Lmo 0440 TGACAAACAGAACATTAACTA TTTGAAATCGAATGTTAAATC CCAA [SEQ ID NO:1503] CA [SEQ ID NO:1504] Lmo 0638 TGCTTGGTTTAACGGATTATC GGCTGTTTGTAATTTATTCGT A [SEQ ID NO:1505] GC [SEQ ID NO:1506] Lmo 0733 GCAAGAAGAAATTGCCATCAA CCTCCTATAAGGATAATCGGT [SEQ ID NO:1507] GC [SEQ ID NO:1508] Lmo 0833 AATAGGGGCTATTCTTTAGCG AAAAGCACAGTCATGCGTAGA G [SEQ ID NO:1509] A [SEQ ID NO:1510] Lmo 1133 GACGTGGCTTATTCAGACACA GCGAACTACTTACCACTTCGC A [SEQ ID NO:1511] T [SEQ ID NO:1512] Lmo 1135 TTAATTGTGGTGCCTGTGTCT AAAATCCCAGCCTATTCCATC C [SEQ ID NO:1513] T [SEQ ID NO:1514] Lmo 2732 TAAAGCTTTCCGGTTTCTCTG GGGCATGATGATGTTTAAATG A [SEQ ID NO:1515] A [SEQ ID NO:1516] Lmo 2733 GAATGCCTTTTATCCAAAGAC AAATCCGGCAATGATACCTAA G [SEQ ID NO:1517] A [SEQ ID NO:1518] Lmo 2734 AACAAGCGCACTTAGAATGAC CATTTTCGAAGCGAATTAGGT A [SEQ ID NO:1519] C [SEQ ID NO:1520] Lmo 2736 GCCAACACGATTGGATTAGATT TCGGCGTCTTTCATTTTATCT [SEQ ID NO:1521] T [SEQ ID NO:1522] II Lmo0017 TCTTAAAAATGCAGGGGTTGA GCCGAATGACCTGAAACATAG T [SEQ ID NO:1523] T [SEQ ID NO:1524] Lmo0094 TGATTATTGGTTTATTGATTG ACTCGCCACAAACAAACTACA GCTT [SEQ ID NO:1525] A [SEQ ID NO:1526] inlH GGGTTACAAAGCATAAAAACG ATGTTAAATTTGGGCTTGCGT C [SEQ ID NO:1527] A [SEQ ID NO:1528] inlE CGATGTTTCTCCACTTACTGG AGCAGGCATTTTATCTATCCC TT [SEQ ID NO:1529] A [SEQ ID NO:1530] Lmo0333 AATCCGGTTATTTGGTATGAC GCAACTGTATAATCTCCGCCT G [SEQ ID NO:1531] T [SEQ ID NO:1532] Lmo0549 TTTATCCCTTTTTCCAAAGCT TTGTAAGACACAACTTGGGGT G [SEQ ID NO:1533] G [SEQ ID NO:1534] Lmo0832 TGATTTTGGTGTCTCAATAGC CAATGCTCGTCTCCATGTTAA A [SEQ ID NO:1535] A [SEQ ID NO:1536] Lmo0834 TGAATATGACACAAAAAGTGG TGAATATGACACAAAAAGTGG TGAT [SEQ ID NO:1537] TGAT [SEQ ID NO:1538] Lmo0835 CATTAGCATAGATGGCTTGC CGAGCTATCACCTGTTTTTG [SEQ ID NO:1539] [SEQ ID NO:1540] Lmo1441 ATGTCGAAGCAACAGTAGCA AATTCCGAGATGCAGAGGAT GA [SEQ ID NO:1541] AA [SEQ ID NO:1542] Lmo1451 AGTAGATGGCGCTAATCGAG CTTGGGCTAAACGAGCAGTAT AA [SEQ ID NO:1543] T [SEQ ID NO:1544]

TABLE 15 Oligonucleotide primers for L. monocytogenes subgroup specific marker genes Gene Forward (5′ to 3′) Reverse (5′ to 3′) A Lmo0171 AACGTATGAAGCGACGATAA AAAACCCCACTTGAATTAGC [SEQ ID NO:1545] [SEQ ID NO:1546] Lmo0172 CCGCATTAATGAAACAAGAA TGGTAGAATGTTTCGCACTT [SEQ ID NO:1547] [SEQ ID NO:1548] Lmo0525 AGGGATTATTATTGGCCGACT TGTGTCTGTCCATGTCATCAA T [SEQ ID NO:1549] A [SEQ ID NO:1550] Lmo0734 CACTACCAAGGAGCTTTTGA ATTCAACGGGAACAATCTCT [SEQ ID NO:1551] [SEQ ID NO:1552] Lmo0735 GAAGCGATGTTTTTCATGTTG TAGCACAAACCCCTTAACACC A [SEQ ID NO:1553] T [SEQ ID NO:1554] Lmo0736 TGGAAATGATCATGTTGGAAT AAATTCTGCATCCAACCAGTT C [SEQ ID NO:1555] T [SEQ ID NO:1556] Lmo0737 ATTATTAGCAGCATTCGGATC AATGTCATTGCGAGTGTACCT G [SEQ ID NO:1557] G [SEQ ID NO:1558] Lmo0738 ATTCTTAGCGTTTGGACCTC AAAGCCAACAAATCCTTTTC [SEQ ID NO:1559] [SEQ ID NO:1560] Lmo0739 GGTCGAGTGAAATATTGGGTT TTGTTTCACAATATGGGTTTG C [SEQ ID NO:1561] G [SEQ ID NO:1562] Lmo1060 TAACCGAAGCAGGGTATCAAG TTGCGTAGATTTTTCATATGC T [SEQ ID NO:1563] G [SEQ ID NO:1564] Lmo1061 ATTAAAATCCCCTCTTGCTG TGATTTCTCAAGGCGATAGA [SEQ ID NO:1565] [SEQ ID NO:1566] Lmo1062 AAACCCCAAGTTTTTCAGTCA CATTTCAAATTTACGCTCACG A [SEQ ID NO:1567] A [SEQ ID NO:1568] Lmo1063 GGGAAACAAAGCTCAAATTGT AATAATGTGTTCCGAGGTTTC T [SEQ ID NO:1569] A [SEQ ID NO:1570] Lmo1968 GTGCAATCAGCCAACAAAATA TTCAAATTCACAGGCATGAAT A [SEQ ID NO:1571] C [SEQ ID NO:1572] Lmo1969 ATGGCAATTATTCGGGATGTA TTGATTGAGCATAGCCTTTGT G [SEQ ID NO:1573] G [SEQ ID NO:1574] Lmo1970 AGTAACACGAGCTGTTGCAT AAATCACACGCACTCCTTTA [SEQ ID NO:1575] [SEQ ID NO:1576] Lmo1971 ACAGGAAATGATCAAGTCGGT AATAATGGCTCCTCGTCTACC T [SEQ ID NO:1577] A [SEQ ID NO:1578] Lmo1973 GGAGGTAGAAAGTCCGGTAG TCCAACTGTAAAGCCATGTT [SEQ ID NO:1579] [SEQ ID NO:1580] Lmo1974 TGACAGTTCGAAAAGCGATAG ATAGGAAGTACGTCGCACATG A [SEQ ID NO:1581] A [SEQ ID NO:1582] bvrC TGAAAACAAGGGTTTTTGGAG TGCTTCGTAAGCTAATTCCCA T [SEQ ID NO:1583] T [SEQ ID NO:1584] bvrB TTTTAGGCTACACGAGTGCAA CTTGCTGTAAATGACATTGGG A [SEQ ID NO:1585] A [SEQ ID NO:1586] B Lmo0151 TGTTGAATAAAACTAGAGGCG AGCTACTTTATCTTTAAACTT AAA [SEQ ID NO:1587] CGCA [SEQ ID NO:1588] Lmo0466 GCAAAAGGAAAAATCCAAGAG ACATGCTTTTTCATGAATTGG A [SEQ ID NO:1589] A [SEQ ID NO:1590] Lmo0467 GCGAATATTGCACTTGTTGAG TACGTCCAAAAGGGTCTACGT A [SEQ ID NO:1591] T [SEQ ID NO:1592] Lmo0469 AATAATTGCGGATTTGGAGAA GGCCAAGTGAATGACCATAGA A [SEQ ID NO:1593] [SEQ ID NO:1594] Lmo0470 CAAACACCGTTTGATAAAGTG TGAAGACTCGTAATGACCCAC C [SEQ ID NO:1595] A [SEQ ID NO:1596] Lmo0471 GGAAGGAAAGGTATTAATCGG TTTTTGAAGGATATTGTGCTC G [SEQ ID NO:1597] G [SEQ ID NO:1598] Lmo1118 AGGGGTCTTAAATCCTGGAAT GAAGTTTTCCGCTCCCTATTT A [SEQ ID NO:1599] T [SEQ ID NO:1600] Lmo1119 GGTTCTGGTCTTGCCTTAGAA TCTCTGGCGCTAAATCATAAG CT [SEQ ID NO:1601] T [SEQ ID NO:1602] C ORF2819 AAATTTTTCAAGGAGGAGCAA CAATGTCTCTTCTTTCGCTTT [SEQ ID NO:1603] T [SEQ ID NO:1604] ORF3840 TCAAATACTTGTCCGCATTTC GCATATTGATAGTGCGTACCG [SEQ ID NO:1605] [SEQ ID NO:1606] ORF2568 GAACGGTCGGTATTTCATTCT AACCGTTTGTGCCTCTTTACT [SEQ ID NO:1607] [SEQ ID NO:1608] ORF1761 ACGCGAAAGATAATTTTGACC CCTTAGAGCAAATCCCCATAG [SEQ ID NO:1609] [SEQ ID NO:1610] ORF0029 CCCAGTGAAAAGTGAAAAAGT CCCAGTGAAAAGTGAAAAAGT [SEQ ID NO:1611] [SEQ ID NO:1612] D ORF0799 AAATTCCAAAAGGACGTGAGT CATTGTTTTTCAACCGTTCAT [SEQ ID NO:1613] [SEQ ID NO:1614] ORF2372 AGATAGCCTGATGCGAGTTTT ACGTTTTAGGATCTCCACCTG [SEQ ID NO:1615] [SEQ ID NO:1616] ORF2110 AGTGGACAATTGATTGGTGAA CATCCATCCCTTACTTTGGAC [SEQ ID NO:1617] [SEQ ID NO:1618]

TABLE 16 a: Example of 192 Genes Representative of the 409 Gene Macroarray L. mono L. ivanovii L. Welshimeri L. seeligeri L. innocua L. gravi-murravi L. mono1/2a-3a L. mono1/2c-3c L. mono1/2b-3b-7 4b-4d-4e L. mono 4c L. mono 4a Gene Lmo0017 0 0 0 0 0 100 100 100 100 100 0 Lmo0017 Lmo0036 100 0 50 0 100 100 100 100 100 0 0 Lmo0036 Lmo0037 100 0 50 0 0 100 100 100 100 0 0 Lmo0037 Lmo0066 50 0 0 25 0 22 100 15 7 100 33 Lmo0066 Lmo0067 0 0 0 25 0 7 100 10 0 0 0 Lmo0067 Lmo0068 0 0 0 25 0 7 100 45 59 0 0 Lmo0068 Lmo0069 0 0 0 0 0 19 100 80 59 0 0 Lmo0069 Lmo0072 0 0 0 25 0 41 100 90 100 0 0 Lmo0072 Lmo0073 0 0 0 0 0 11 100 50 59 0 0 Lmo0073 Lmo0079 33 0 50 0 0 67 92 100 81 100 0 Lmo0079 Lmo0080 0 0 50 0 0 48 100 95 85 0 0 Lmo0080 Lmo0081 0 0 0 0 0 15 92 35 0 0 0 Lmo0081 Lmo0082 0 0 0 0 0 100 100 100 100 100 100 Lmo0082 Lmo0083 0 0 0 0 0 100 100 100 100 100 100 Lmo0083 Lmo0094 0 0 0 0 0 100 100 100 100 0 0 Lmo0094 Lmo0106 33 50 100 0 0 96 100 35 96 100 100 Lmo0106 Lmo0141 0 0 0 0 0 30 100 25 96 50 100 Lmo0141 Lmo0143 0 0 0 0 0 22 100 5 7 0 100 Lmo0143 Lmo0144 0 0 0 0 0 11 100 25 96 50 100 Lmo0144 Lmo0147 83 50 50 63 0 100 100 65 85 100 67 Lmo0147 Lmo0151 0 0 0 0 0 11 100 0 0 0 0 Lmo0151 Lmo0171 0 0 0 0 0 100 100 0 0 0 0 Lmo0171 Lmo0172 0 0 0 0 0 100 100 0 0 0 0 Lmo0172 Lmo0252 0 100 50 0 0 44 100 0 0 100 100 Lmo0252 Lmo0255 0 0 0 0 0 93 100 30 22 100 100 Lmo0255 Lmo0304 0 50 0 50 0 56 100 90 7 50 0 Lmo0304 Lmo0310 0 0 0 0 0 7 100 30 4 0 0 Lmo0310 Lmo0320 0 0 0 13 0 85 100 90 100 0 33 Lmo0320 Lmo0333 0 0 0 0 0 100 100 100 100 100 0 Lmo0333 Lmo0334 0 50 0 0 0 100 100 100 100 100 0 Lmo0334 Lmo0338 33 0 0 13 50 67 100 0 0 0 0 Lmo0338 Lmo0378 0 0 0 50 0 100 92 75 19 0 0 Lmo0378 Lmo0379 0 0 0 25 0 85 100 0 0 100 0 Lmo0379 Lmo0380 0 0 0 25 0 96 92 75 19 100 0 Lmo0380 Lmo0381 0 0 0 25 0 100 100 75 19 0 100 Lmo0381 Lmo0409 0 0 0 0 0 78 100 60 78 0 0 Lmo0409 Lmo0419 0 100 0 0 0 100 100 100 100 100 0 Lmo0419 Lmo0440 0 0 0 0 0 100 100 100 100 100 100 Lmo0440 Lmo0444 0 100 0 0 0 37 100 65 0 100 0 Lmo0444 Lmo0448 0 100 0 63 0 44 100 95 63 100 33 Lmo0448 Lmo0459 0 0 0 0 0 48 100 100 100 50 100 Lmo0459 Lmo0462 0 0 0 0 0 48 92 100 100 50 100 Lmo0462 Lmo0466 0 0 0 0 0 11 100 0 0 0 0 Lmo0466 Lmo0467 0 0 0 0 0 11 100 0 0 0 0 Lmo0467 Lmo0471 0 0 0 0 0 11 100 0 0 0 0 Lmo0471 Lmo0472 0 50 0 88 0 81 100 25 4 100 0 Lmo0472 Lmo0473 67 50 0 38 0 93 100 20 67 100 100 Lmo0473 Lmo0474 0 0 0 25 0 93 100 10 100 0 0 Lmo0474 Lmo0493 67 0 100 0 0 85 100 100 100 50 0 Lmo0493 Lmo0497 0 0 0 0 0 100 100 100 4 0 0 Lmo0497 Lmo0525 0 50 0 0 0 100 100 0 0 0 0 Lmo0525 Lmo0549 0 0 0 0 0 100 100 100 100 100 0 Lmo0549 Lmo0630 50 100 0 0 0 100 100 95 81 50 0 Lmo0630 Lmo631 0 100 0 0 0 100 100 100 81 50 0 Lmo0631 Lmo0632 100 100 0 0 0 100 100 100 81 50 0 Lmo0632 Lmo0732 50 50 0 75 0 100 100 80 70 100 100 Lmo0732 Lmo0733 0 0 0 0 0 100 100 100 100 100 100 Lmo0733 Lmo0734 0 100 0 0 0 100 100 0 0 0 0 Lmo0734 Lmo0735 17 50 0 0 0 100 100 0 0 0 0 Lmo0735 Lmo0739 0 0 0 0 0 100 100 0 0 0 0 Lmo0739 Lmo0750 0 0 0 0 0 100 100 0 4 0 100 Lmo0750 Lmo0751 17 0 0 0 0 96 100 60 81 0 100 Lmo0751 Lmo0752 100 0 0 0 0 100 100 100 100 0 100 Lmo0752 Lmo0753 100 0 0 0 0 100 100 100 100 0 100 Lmo0753 Lmo0780 33 50 0 0 0 100 100 15 7 100 100 Lmo0780 Lmo0801 0 50 50 13 0 70 100 0 30 0 33 Lmo0801 Lmo0804 0 0 0 0 0 44 100 45 33 100 100 Lmo0804 Lmo0832 0 0 0 0 0 100 100 100 100 0 0 Lmo0832 Lmo0833 0 0 0 0 0 100 100 100 100 100 33 Lmo0833 Lmo0834 0 0 0 0 0 100 100 100 100 100 0 Lmo0834 Lmo0835 0 0 0 0 0 100 100 100 100 0 0 Lmo0835 Lmo0842 17 100 0 75 0 100 100 95 48 0 33 Lmo0842 Lmo1030 100 0 0 0 0 100 100 100 100 100 0 Lmo1030 Lmo1036 100 0 0 0 0 100 100 100 100 100 0 Lmo1036 Lmo1060 0 100 0 0 0 100 100 0 0 0 0 Lmo1060 Lmo1061 0 50 0 0 0 100 100 0 0 0 0 Lmo1061 Lmo1063 0 100 0 0 0 100 100 0 0 0 0 Lmo1063 Lmo1076 0 0 100 0 0 100 100 100 0 0 0 Lmo1076 Lmo1077 0 0 100 0 100 100 100 100 0 0 0 Lmo1077 Lmo1080 0 0 50 0 0 100 100 100 0 0 0 Lmo1080 Lmo1081 0 0 100 0 0 100 100 100 0 0 0 Lmo1081 Lmo1082 0 0 100 0 0 100 100 100 0 0 0 Lmo1082 Lmo1085 0 0 0 0 0 100 100 100 0 0 0 Lmo1085 Lmo1088 0 0 50 0 0 100 100 100 0 0 0 Lmo1088 Lmo1090 0 0 100 0 0 100 100 100 0 50 0 Lmo1090 Lmo1091 0 0 100 0 0 100 100 100 0 0 0 Lmo1091 Lmo1102 100 0 50 13 0 78 100 65 78 100 100 Lmo1102 Lmo1115 33 0 50 13 0 78 75 10 4 100 33 Lmo1115 Lmo1116 67 0 0 63 0 48 100 60 81 50 0 Lmo1116 Lmo1118 17 0 0 0 0 4 100 0 0 0 0 Lmo1118 Lmo1119 0 0 0 0 0 4 100 0 0 0 0 Lmo1119 Lmo1120 67 50 50 25 0 85 100 95 85 0 0 Lmo1120 Lmo1133 0 0 0 0 0 100 100 100 100 100 100 Lmo1133 Lmo1135 0 0 0 0 0 100 100 100 100 100 33 Lmo1135 Lmo1307 33 50 0 0 0 100 100 0 0 100 100 Lmo1307 Lmo1441 0 0 0 0 0 100 100 100 100 0 0 Lmo1441 Lmo1451 0 0 0 0 0 100 100 100 100 0 0 Lmo1451 Lmo1597 67 100 0 0 0 63 100 85 19 0 0 Lmo1597 Lmo1604 33 0 0 75 0 100 100 75 67 100 33 Lmo1604 Lmo1648 17 50 0 25 0 78 100 20 7 50 0 Lmo1648 Lmo1666 0 0 50 0 0 100 100 100 100 0 0 Lmo1666 Lmo1714 0 0 0 25 0 41 100 100 100 0 100 Lmo1714 Lmo1968 0 0 0 13 0 100 100 0 0 0 0 Lmo1968 Lmo1973 0 0 0 13 0 100 100 0 0 0 0 Lmo1973 Lmo1974 0 0 0 13 0 100 100 0 0 0 0 Lmo1974 Lmo2026 0 0 0 0 0 41 100 0 0 0 0 Lmo2026 Lmo2027 0 0 0 0 0 93 100 75 70 100 0 Lmo2027 Lmo2276 0 0 0 0 0 78 75 70 67 0 0 Lmo2276 Lmo2277 17 0 0 25 0 56 42 10 11 50 33 Lmo2277 Lmo2311 0 0 0 0 0 41 75 5 0 50 100 Lmo2311 Lmo2312 0 50 0 25 0 56 75 80 33 0 100 Lmo2312 Lmo2324 0 50 0 38 0 63 83 35 41 0 67 Lmo2324 Lmo2408 0 100 0 0 0 37 100 0 0 0 0 Lmo2408 Lmo2443 0 0 0 0 0 89 100 95 100 0 100 Lmo2443 Lmo2576 0 0 0 0 0 100 100 0 0 100 0 Lmo2576 Lmo2594 0 0 0 50 0 74 92 80 100 100 33 Lmo2594 Lmo2595 0 0 0 0 0 52 100 40 100 50 100 Lmo2595 Lmo2671 17 100 50 0 0 100 100 100 100 0 0 Lmo2671 Lmo2686 17 0 0 0 0 93 100 5 0 50 0 Lmo2686 Lmo2732 0 0 0 0 0 100 100 100 100 100 100 Lmo2732 Lmo2736 0 0 0 0 0 100 100 100 100 100 100 Lmo2736 Lmo2786 0 0 0 0 0 100 100 0 0 100 0 Lmo2786 Lmo2787 0 0 0 0 0 100 100 0 0 100 0 Lmo2787 Lmo2807 17 0 50 13 0 63 100 15 48 0 67 Lmo2807 Lmo2809 0 0 50 25 0 70 92 100 44 0 0 Lmo2809 Lmo2821 0 0 0 0 0 100 100 100 100 100 0 Lmo2821 Lin0060 0 0 0 63 0 4 0 15 22 0 0 Lin0060 Lin0197 100 100 100 100 0 0 0 0 0 0 0 Lin0197 Lin0332 0 0 0 38 0 0 0 0 0 0 0 Lin0332 Lin0397 0 0 0 50 0 0 0 0 0 0 0 Lin0397 Lin0415 0 100 50 100 0 70 75 70 78 100 0 Lin0415 Lin0453 0 100 0 100 0 0 0 0 100 0 0 Lin0453 Lin0454 17 100 0 100 0 0 0 0 100 100 100 Lin0454 Lin0455 33 50 0 100 0 0 0 0 67 50 100 Lin0455 Lin0465 0 0 0 100 0 11 0 0 0 0 0 Lin0465 Lin0476 0 0 0 38 0 59 67 40 30 100 0 Lin0476 Lin0661 0 0 0 100 0 52 50 5 15 50 0 Lin0661 Lin0665 0 50 100 100 0 59 58 100 100 100 100 Lin0665 Lin0677 0 0 0 100 0 11 0 0 0 100 100 Lin0677 Lin0739 0 0 0 100 0 0 0 0 0 0 0 Lin0739 Lin0740 0 0 0 100 0 74 75 40 30 100 67 Lin0740 Lin0803 0 0 0 100 0 0 0 0 0 0 0 Lin0803 Lin0868 0 0 0 50 0 0 0 0 0 0 0 Lin0868 Lin1066 0 0 0 50 0 0 0 0 4 0 0 Lin1066 Lin1069 0 0 0 63 0 0 0 0 0 0 0 Lin1069 Lin1073 83 50 0 100 0 0 0 0 100 100 100 Lin1073 Lin1083 0 0 0 38 0 7 0 35 0 0 0 Lin1083 Lin1084 17 50 100 88 0 59 0 100 85 0 0 Lin1084 Lin1090 67 0 0 75 0 0 0 100 100 100 67 Lin1090 Lin1204 0 0 0 63 0 0 0 90 100 0 100 Lin1204 Lin1262 0 0 0 75 0 74 75 50 67 100 67 Lin1262 Lin1299 33 0 50 100 0 78 92 70 78 100 67 Lin1299 Lin1328 83 0 50 100 0 74 75 50 70 100 67 Lin1328 Lin1452 0 0 0 100 0 0 0 5 0 0 0 Lin1452 Lin1621 0 0 0 88 0 0 0 0 0 0 100 Lin1621 Lin2397 0 50 50 75 0 41 33 30 11 0 0 Lin2397 Lin2494 0 100 50 100 0 89 100 95 41 100 100 Lin2494 Lin2603 0 0 50 63 0 30 50 30 11 0 100 Lin2603 Lin2724 17 0 0 100 0 0 0 0 0 50 100 Lin2724 Lin2741 0 0 0 100 0 0 0 0 0 0 0 Lin2741 Lin2743 17 50 50 88 0 52 0 60 0 50 0 Lin2743 Lin2744 17 50 50 100 0 67 67 75 7 100 0 Lin2744 Lin2839 0 0 0 100 0 30 0 25 0 0 0 Lin2839 Lin2918 0 0 0 100 0 0 0 0 0 0 0 Lin2918 ORF 2372 33 100 0 0 0 0 0 0 100 0 0 ORF 2372.1 ORF 2110 67 50 0 0 0 0 0 0 100 0 0 ORF 2110.1 ORF 799 0 50 0 63 0 7 0 0 100 0 0 ORF 799.1 ORF 3840 17 0 0 0 0 0 0 100 100 0 0 ORF 3840.1 ORF 2017a 0 0 0 0 0 0 0 100 100 0 0 ORF 1761.1 ORF 2819 0 0 0 0 0 0 0 100 100 0 0 ORF 2819.1 ORF 2541 0 0 0 0 0 30 0 100 100 0 0 ORF 2541.1 ORF 2017b 50 0 0 25 0 26 0 100 100 100 33 ORF 2017.1 ORF 3401 33 0 0 25 0 11 0 50 100 0 33 ORF 3401.1 ORF 2074 100 100 50 50 0 48 0 100 100 0 100 ORF 2074.1 ORF 2777 50 50 100 0 0 33 0 100 100 0 0 ORF 2777.1 ORF 2579 100 100 50 38 0 52 0 95 100 0 100 ORF 2579.1 ORF 660 0 0 0 0 0 33 0 10 100 0 0 ORF 660.1 ORF 1445 50 0 0 0 0 0 0 0 100 100 100 ORF 1445.1 ORF 1590 0 0 0 0 0 100 0 95 100 100 0 ORF 1590.1 ORF 1491 33 100 100 0 0 0 0 100 100 100 0 ORF 1491.1 ORF 3792 17 0 0 0 0 67 17 100 100 100 100 ORF 3792.1 ORF 4101 67 100 0 75 0 59 42 95 100 100 33 ORF 4101.1 ORF 1490 33 100 100 0 100 4 0 100 100 100 0 ORF 1490.1 ORF 2858 50 50 50 50 100 74 75 90 100 100 33 ORF 2858.1 ORF 757 0 0 0 38 0 4 0 35 100 0 0 ORF 757.1 ORF 2076 100 100 50 50 0 48 0 100 100 0 100 ORF 2076.1 ORF 3184 33 50 0 25 0 26 33 70 96 50 33 ORF 3184.1 ORF 2847 0 0 0 0 0 7 0 0 74 0 100 ORF 2847.1 ORF 105 67 0 0 25 0 0 0 75 70 0 0 ORF 105.1 ORF 1390 33 0 50 25 0 26 8 15 56 0 67 ORF 1390.1 ORF 3103 0 0 0 25 0 67 0 50 41 0 0 ORF 3103.1 ORF 817 33 0 0 13 0 0 0 95 37 50 0 ORF 817.1 Gene description Gene function category Lmo0017 372aa/unknown, similar to Bacillus anthracis CapA Cell wall protein (polyglutamate capsule biosynthesis) Lmo0036 341aa/unknown, similar to ornithine Metabolism of amino acids and carbamoyltransferase, related molecules Lmo0037 461aa/unknown, similar to amino acid transporter Transport/binding proteins and lipoproteins Lmo0066 604aa/unknwon, similar to toxin components miscellaneous Lmo0067 329aa/unknown, similar to dinitrogenase reductase Protein modification ADP-ribosylation system Lmo0068 107aa/unknwon unknown Lmo0069 97aa/unknwon unknown Lmo0072 67aa/unknown, Hypothetical unknown Lmo0073 94aa/unknwon unknown Lmo0079 492aa/unknown unknown Lmo0080 132aa/unknwon unknown Lmo0081 200aa/unknwon unknown Lmo0082 108aa/Unknwon unknown Lmo0083 122aa/unknown, similar to transcription regulator Régulation (merR family) Lmo0094 186aa/unknwon unknown Lmo0106 300aa/unknown, similar to transcription regulator Régulation Lmo0141 80aa/unknwon unknown Lmo0143 58aa/unknwon unknown Lmo0144 147aa/unknwon unknown Lmo0147 145aa/unknwon unknown Lmo0151 135aa/unknwon unknown Lmo0171 832aa/unknwon, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) Lmo0172 112aa/unknown, similar to transposase C-terminal Transposon and IS part Lmo0252 128aa/unknown, similar to repressor (penicilinase Régulation repressor) Lmo0255 167aa/unknown, similar to unknown protein unknown Lmo0304 421aa/Unknwon unknown Lmo0310 358aa/unknown unknown Lmo0320 399aa/unknown, similar to surface protein cell surface proteins (peptidoglycan bound, LPXTG motif) Lmo0333 1778aa/unknown, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) Lmo0334 174aa/unknwon unknown Lmo0338 126aa/unknwon unknown Lmo0378 148aa/unknown unknown Lmo0379 151aa/unknwon unknown Lmo0380 209aa/unknwon unknown Lmo0381 128aa/unknwon unknown Lmo0409 821aa/inIF Internalin, putative peptidoglycan bound cell surface proteins protein (LPXTG motif) Lmo0419 184aa/unknown, similar to unknown protein unknown Lmo0440 167aa/unknown unknown Lmo0444 926aa/unknown, conserved hypothetical protein unknown Lmo0448 483/unknown, similar to amino acid antiporter Transport/binding proteins and lipoproteins Lmo0459 512aa/unknown, similar to transcription regulator Régulation (VirR from Streptococcus pyogenes) Lmo0462 161aa/unknwon unknown Lmo0466 567aa/unknown unknown Lmo0467 107aa/unknwon unknown Lmo0471 336aa/unknwon unknown Lmo0472 295aa/unknwon unknown Lmo0473 361aa/unknwon unknown Lmo0474 115aa/unknwon unknown Lmo0493 586aa/unknown, similar to acylase Detoxification Lmo0497 502aa/unknown, similar to sugar transferase Cell wall Lmo0525 443aa/unknwon unknown Lmo0549 673aa/unknown, similar to internalin protein cell surface proteins Lmo0630 676aa/unknown, similar to transcription Régulation antiterminator BgIG family Lmo631 150aa/unknown, similar to PTS system, fructose- Transport/binding proteins and specific IIA component lipoproteins Lmo0632 353aa/unknown, similar to PTS system, fructose- Transport/binding proteins and specific IIC component, lipoproteins Lmo0732 638aa/unknown, putative peptidoglycan bound cell surface proteins protein (LPXTG motif) Lmo0733 169aa/unknown, similar to transcription regulator R+E acu egulation Lmo0734 334aa/unknown, similar to transcriptional regulator Régulation (Lacl family) Lmo0735 223aa/unknown, similar to Ribulose-5-Phosphate 3- Specific pathways Epimerase Lmo0739 457aa/unknown, similar to 6-phospho-beta- Specific pathways glucosidase Lmo0750 171aa/unknwon unknown Lmo0751 98aa/unknwon unknown Lmo0752 278aa/unknown, weakly similar to a putative Detoxification haloacetate dehalogenase Lmo0753 226aa/unknown, similar to transcription regulator Régulation Crp/Fnr family Lmo0780 115aa/unknown unknown Lmo0801 646aa/unknown, similar to internalin, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0804 156aa/Unknwon unknown Lmo0832 94aa/unknown, similar to transposase Tranaposon and IS Lmo0833 296aa/unknown; similar to transcriptional regulator Regulation Lmo0834 237aa/Unknwon unknown Lmo0835 334aa/unknown, putative peptidoglycan bound cell surface proteins protein (LPXTG motif) Lmo0842 2044aa/unknown, surface protein (LPXTG motif) cell surface proteins Lmo1030 342aa/unknown, similar to transcriptional regulator Régulation Lacl family Lmo1036 421aa/unknwon unknown Lmo1060 220aa/unknown, similar to transcription response Régulation regulator Lmo1061 481aa/unknown, similar to sensor protein histidine Sensors (signal transduction) kinases (2 components regulatory systems) Lmo1063 222aa/unknown, similar to ABC transporter (ATP Transport/binding proteins and binding protein), lipoproteins Lmo1076 572aa/unknown, similar to AUTOLYSIN (EC 3.5.1.28) Cell wall (N-ACETYLMURAMOYL-L-ALANINE AMIDASE) Lmo1077 562aa/unknown, similar to teichoic acid biosynthesis Cell wall protein B Lmo1080 623aa/unknown, similar to B. subtilis minor teichoic Cell wall acids biosynthesis protein GgaB Lmo1081 288aa/unknown, similar to glucose-1-phosphate Cell wall thymidyl transferase Lmo1082 186aa/unknown, similar to dTDP-sugar epimerase Cell wall Lmo1085 696aa/unknown, similar to teichoic acid biosynthesis Cell wall protein B Lmo1088 386aa/tagB: unknown, similar to teichoic acid Cell wall biosynthesis protein B precursor Lmo1090 327aa/unknown, similar to glycosyltransferases Cell wall Lmo1091 337aa/unknown, siumilar to glysosyltransferases Cell wall Lmo1102 111aa/unknown, similar to cadmium efflux system Detoxification accessory proteins Lmo1115 862aa/unknown, similar to fibrinogen-binding protein cell surface proteins (LPXTG motif) Lmo1116 257aa/unknown, similar to regulatory proteins Régulation Lmo1118 505aa/unknwon unknown Lmo1119 285aa/unknown, similar to methylases DNA restriction/modification and repair Lmo1120 138aa/unknwon unknown Lmo1133 102aa/unknown, similar to B. subtilis YjcS protein unknown Lmo1135 383aa/unknwon unknown Lmo1307 280aa/unknwon unknown Lmo1441 368aa/unknown, similar to putative peptidoglycan Cell wall acetylation protein Lmo1451 331aa/unknown, similar to E. coli LytB protein unknown Lmo1597 259aa/unknwon unknown Lmo1604 181aa/unknown unknown Lmo1648 120aa/unknwon unknown Lmo1666 1711aa/unknown, peptidoglycan linked protein cell surface proteins (LPxTG) Lmo1714 190aa/unknwon unknown Lmo1968 247aa/unknown, similar to creatinine Metabolism of amino acids and amidohydrolases related molecules Lmo1973 147aa/unknown, similar to PTS system enzyme II A Transport/binding proteins and component lipoproteins Lmo1974 249aa/unknown, similar to transcription regulators Régulation (GntR family) Lmo2026 626aa/unknown, peptidoglycan linked protein cell surface proteins (LPxTG) Lmo2027 367aa/unknown, putative cell surface protein, similar cell surface proteins to internalin proteins Lmo2276 165aa/unknown, similar to an unknown Phage-related functions bacteriophage protein Lmo2277 183aa/unknwon unknown Lmo2311 153aa/unknwon unknown Lmo2312 156aa/unknwon unknown Lmo2324 258aa/unknown, similar to anti-repressor Régulation [Bacteriophage A118] Lmo2408 67aa/unknown, similar to repressor protein Régulation Lmo2443 139aa/unknwon unknown Lmo2576 1530aa/unknwo, peptidoglycan anchored protein cell surface proteins (LPXTG motif) Lmo2594 119aa/unknwon unknown Lmo2595 289aa/unknown, similar to unknown proteins unknown Lmo2671 122aa/unknwon unknown Lmo2686 177aa/unknwon unknown Lmo2732 250aa/unknwon unknown Lmo2736 377aa/unknown, conserved hypothetical protein unknown Lmo2786 327aa/bvrC Lmo2787 640aa/bvrB-beta-glucoside-specific Transport/binding proteins and phosphotransferase enzyme II lipoproteins Lmo2807 127aa/unknown, hypothetical secreted protein unknown Lmo2809 126aa/unknown, hypothetical secreted protein unknown Lmo2821 851aa/unknown, similar to internalin, unknown Cell surface proteins putative peptidoglycan bound protein (LPXTG motif) Lin0060 204aa/unknown unknown Lin0197 358aa/unknown, similar to chloromuconate Metabolism of carbohydrates cycloisomerase ykfB of B. subtilis (Specific pathways) Lin0332 405aa/unknown, similar to putative permeases Transport/binding proteins and lipoproteins Lin0397 120aa/unknwon unknown Lin0415 410aa/unknown, probable cell surface protein cell surface proteins (LPXTG motif) Lin0453 169aa/unknown unknown Lin0454 2167aa/unknown, similar to cell wall-associated cell surface proteins protein precursor wapA (B. subtilis) Lin0455 184aa/unknwon unknown Lin0465 212aa/unknown, conserved hypothetical protein unknown similar to yoaZ B. subtilis Lin0476 350aa/unknwon unknown Lin0661 596aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0665 831aa/unknown, highly similar to ORFA of Listeria cell surface proteins seeligeri (LPXTG motif) Lin0677 293aa/unknown, conserved hypothetical protein unknown Lin0739 521aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0740 657aa/unknown, probable cell surface protein Cell surface proteins (LPXTG motif) Lin0803 1386aa/unknown, surface protein (LPXTG motif) cell surface proteins Lin0868 378aa/unknwon unknown Lin1066 329aa/unknown, similar to dolichol, phosphate Cell wall mannose synthase Lin1069 336aa/unknwon unknown Lin1073 462aa/unknown, similar to galactosamine-containing Cell wall minor teichoic acid biosynthesis protein GgaA Lin1083 216aa/unknwon unknown Lin1084 94aa/unknwon unknown Lin1090 111aa/unknwon unknown Lin1204 1237aa/unknown, similar to internalin proteins Cell surface proteins (LPXTG motif) Lin1262 445aa/unknwon unknown Lin1299 121aa/unknwon unknown Lin1328 620aa/unknown, internalin like protein (LPXTG motif) Cell surface proteins Lin1452 125aa/unknwon unknown Lin1621 253aa/unknown, similar to ketoacyl reductases Metabolism of lipids Lin2397 190aa/unknown, similar to sigma factor-like positive RNA synthesis (Initiation) control protein of B. subtilis Lin2494 124aa/unknown, hypothetical protein unknown Lin2603 95aa/unknwon unknown Lin2724 938aa/unknown, internalin-like protein (LPXTG motif) cell surface proteins Lin2741 152aa/unknwon unknown Lin2743 98aa/unknwon unknown Lin2744 1334aa/unknown, similar to hypothetical proteins unknown Lin2839 99aa/unknwon unknown Lin2918 159aa/unknwon unknown ORF 2372 596pb/unknown, similar ti teichoic acid biosynthesis cell wall protein C ORF 2110 597pb/unknown, similar to hypothetical protein unknown ORF 799 453pb/unknown unknown ORF 3840 593pb/unknown, similar to transcription regulator Régulation ORF 2017a 599pb/unknwon, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) ORF 2819 562pb/unknown, similar to transcriptional regulator Régulation ORF 2541 590pb/unknwon, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) ORF 2017b 285pb/unknwon, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) ORF 3401 575pb/unknown unknown ORF 2074 599pb/unknown similar to oligo-1,6-glucosidase Specific pathways ORF 2777 600pb/unknown unknown ORF 2579 601pb/unknown, sucrose phosphorylase Specific pathways ORF 660 603pb/unknown unknown ORF 1445 607pb/unknown, conserved hypothetical protein unknown ykcB - Bacillus subtills ORF 1590 588pb/unknwon, similar to internalin proteins cell surface proteins putative peptidoglycan bound protein (LPXTG motif) ORF 1491 598pb/unknown, similar to hypothetical protein unknown ORF 3792 594pb/unknown unknown ORF 4101 613pb/unknown, similar to similar to ABC Transport/binding proteins and transporter lipoproteins ORF 1490 474pb/unknown, similar to sucrose Transport/binding proteins and phosphotransferase enzyme IIBC component lipoproteins ORF 2858 249pb/unknown, similar to hypothetical protein unknown ORF 757 522pb/unknown unknown ORF 2076 597pb/unknown, similar to maltodextrin ABC Transport/binding proteins and transporter lipoproteins ORF 3184 597pb/unknown unknown ORF 2847 590pb/similar to phage integrase Phage-related functions ORF 105 599pb/unknown, similar to similar to ABC Transport/binding proteins and transporter lipoproteins ORF 1390 624pb/unknown, similar to hypothetical protein unknown ORF 3103 600pb/unknown, similar to peptidoglycan lytic cell wall protein P45 ORF 817 594pb/unknown unknown b:Example of 192 Genes Representative of the 409 Gene Macroarray Gene CLIP42636-1/2aE CLIP61523-1/2a CLIP42651-1/2a CLIP42663-1/2a CLIP46661-1/2a CLIP46664-1/2a CLIP46682-1/2a CLIP61634-1/2a CLIP9429-1/2a CLIP61678-1/2a Lmo0017 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 Lmo0066 0 0 0 0 0 0 2 0 0 2 Lmo0067 0 0 0 0 0 0 0 0 0 2 Lmo0068 0 0 0 0 0 0 0 0 0 2 Lmo0069 0 0 0 0 0 0 0 0 0 2 Lmo0071 0 0 0 0 0 0 0 0 0 2 Lmo0072 0 0 0 2 0 2 2 0 0 2 Lmo0079 0 2 2 2 2 2 2 0 2 2 Lmo0080 0 0 2 2 2 2 2 0 0 2 Lmo0081 0 0 0 0 0 0 0 0 0 2 Lmo0082 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 2 2 2 2 2 Lmo0141 0 0 2 0 0 0 0 0 0 2 Lmo0143 0 0 0 2 0 2 2 0 0 2 Lmo0144 0 0 0 0 0 0 0 0 0 2 Lmo0147 2 2 2 2 2 2 2 2 2 2 Lmo0151 0 0 0 0 0 0 0 0 0 2 Lmo0171 2 2 2 2 2 2 2 2 2 2 Lmo0172 2 2 2 2 2 2 2 2 2 2 Lmo0252 0 0 0 2 2 2 2 0 0 2 Lmo0253 0 0 0 2 2 2 2 0 0 2 Lmo0304 2 2 2 2 2 2 2 2 0 2 Lmo0310 0 0 0 0 0 0 0 0 0 2 Lmo0320 0 2 2 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 Lmo0338 0 0 2 2 2 2 2 0 0 2 Lmo0378 2 2 2 2 2 2 2 2 2 2 Lmo0379 2 2 2 2 2 2 2 2 2 2 Lmo0380 2 2 2 2 2 2 2 0 2 2 Lmo0381 2 2 2 2 2 2 2 2 2 2 Lmo0409 2 2 2 0 0 0 0 2 2 2 Lmo0419 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 Lmo0444 2 2 2 0 0 0 0 2 0 0 Lmo0448 2 2 2 0 0 0 0 2 0 2 Lmo0459 0 0 0 2 2 2 2 0 0 2 Lmo0462 0 0 0 2 2 2 2 0 0 2 Lmo0466 0 0 0 0 0 0 0 0 0 2 Lmo0467 0 0 0 0 0 0 0 0 0 2 Lmo0471 0 0 0 0 0 0 0 0 0 2 Lmo0472 0 0 2 2 2 2 2 2 2 2 Lmo0473 2 0 2 2 2 2 2 2 2 2 Lmo0474 2 2 0 2 2 2 2 2 2 2 Lmo0493 2 2 2 2 2 2 2 2 2 2 Lmo0497 2 2 2 2 2 2 2 2 2 2 Lmo0525 2 2 2 2 2 2 2 2 2 2 Lmo0549 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 2 2 2 2 Lmo0733 2 2 2 2 2 2 2 2 2 2 Lmo0734 2 2 2 2 2 2 2 2 2 2 Lmo0735 2 2 2 2 2 2 2 2 2 2 Lmo0739 2 2 2 2 2 2 2 2 2 2 Lmo0750 2 2 2 2 2 2 2 2 2 2 Lmo0751 2 2 2 2 2 2 2 0 2 2 Lmo0752 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 Lmo0780 2 2 2 2 2 2 2 2 2 2 Lmo0801 0 2 0 2 2 2 2 2 2 0 Lmo0804 0 0 0 2 2 2 2 0 0 0 Lmo0832 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 Lmo1060 2 2 2 2 2 2 2 2 2 2 Lmo1061 2 2 2 2 2 2 2 2 2 2 Lmo1063 2 2 2 2 2 2 2 2 2 2 Lmo1076 2 2 2 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 2 2 2 Lmo1102 2 2 2 2 2 2 2 0 2 2 Lmo1115 2 2 2 2 2 2 2 2 2 2 Lmo1116 2 2 0 0 0 0 0 2 0 2 Lmo1118 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 Lmo1120 2 2 2 2 2 2 2 2 2 2 Lmo1133 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 Lmo1307 2 2 2 2 2 2 2 2 2 2 Lmo1441 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 Lmo1597 2 2 0 2 2 2 2 2 0 2 Lmo1604 2 2 2 2 2 2 2 2 2 2 Lmo1648 2 0 2 2 2 0 2 2 2 2 Lmo1666 2 2 2 2 2 2 2 2 2 2 Lmo1714 0 0 2 2 2 2 2 0 0 2 Lmo1968 2 2 2 2 2 2 2 2 2 2 Lmo1973 2 2 2 2 2 2 2 2 2 2 Lmo1974 2 2 2 2 2 2 2 2 2 2 Lmo2026 2 2 2 0 0 0 0 2 0 2 Lmo2027 2 2 2 2 2 2 2 2 2 2 Lmo2276 2 2 2 2 2 2 2 2 2 2 Lmo2277 0 2 2 2 2 0 2 2 2 0 Lmo2311 0 2 2 2 2 2 2 0 0 2 Lmo2312 0 2 2 2 2 2 2 0 0 0 Lmo2324 2 2 0 2 2 2 2 0 2 0 Lmo2408 2 2 0 0 0 0 0 2 0 2 Lmo2443 2 2 2 2 2 2 2 2 0 2 Lmo2576 2 2 2 2 2 2 2 2 2 2 Lmo2594 2 2 2 0 0 0 0 2 2 2 Lmo2595 0 0 2 0 0 0 0 0 2 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 Lmo2686 2 2 2 2 2 2 2 2 2 2 Lmo2732 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 Lmo2786 2 2 2 2 2 2 2 2 2 2 Lmo2787 2 2 2 2 2 2 2 2 2 2 Lmo2807 0 0 0 2 2 2 2 0 2 2 Lmo2809 0 2 0 2 2 2 2 0 2 2 Lmo2821 2 2 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 0 0 0 Lin0197 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 Lin0415 0 2 2 2 2 2 2 2 2 2 Lin0453 0 0 0 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 0 0 0 Lin0465 0 0 0 0 0 0 0 0 0 0 Lin0476 2 2 2 2 2 2 2 2 2 0 Lin0661 0 2 2 2 2 2 2 2 2 0 Lin0665 0 2 2 0 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 Lin0740 2 2 2 2 2 2 2 2 2 2 Lin0803 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 Lin1073 0 0 0 0 0 0 0 0 0 0 Lin1083 0 0 0 0 0 0 0 0 0 0 Lin1084 2 2 0 0 0 0 0 2 2 2 Lin1090 0 0 0 0 0 0 0 0 0 0 Lin1204 0 0 0 0 0 0 0 0 0 0 Lin1262 2 2 2 2 2 2 2 2 2 2 Lin1299 2 2 2 2 2 2 2 2 2 2 Lin1328 2 2 2 2 2 2 2 2 2 2 Lin1452 0 0 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 0 0 Lin2397 0 0 2 2 2 2 2 0 0 0 Lin2494 2 2 2 2 2 2 2 2 2 2 Lin2603 0 0 2 0 0 0 0 0 0 0 Lin2724 0 0 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 0 0 Lin2743 2 2 0 2 2 2 2 2 0 0 Lin2744 2 2 0 2 2 2 2 2 2 2 Lin2839 0 0 0 2 2 2 2 0 2 0 Lin2918 0 0 0 0 0 0 0 0 0 0 ORF 105 0 0 0 0 0 0 0 0 0 0 ORF 1390 0 0 2 2 2 0 0 0 2 0 ORF 1445 0 0 0 0 0 0 0 0 0 0 ORF 1490 0 0 0 0 0 0 0 0 0 0 ORF 1491 0 0 0 0 0 0 0 0 0 0 ORF 1590 2 2 2 2 2 2 2 2 2 2 ORF 1761 0 0 0 0 0 0 0 0 0 0 ORF 2017 2 0 2 2 2 0 0 2 2 0 ORF 2074 0 0 2 2 2 2 2 0 0 0 ORF 2076 0 0 2 2 2 2 2 0 0 0 ORF 2110 0 0 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 0 0 ORF 2541 0 0 0 2 2 2 2 0 0 0 ORF 2579 0 0 2 2 2 2 2 0 0 0 ORF 2777 0 0 2 2 2 2 2 0 2 0 ORF 2819 0 0 0 0 0 0 0 0 0 0 ORF 2847 0 0 0 0 0 0 0 0 0 0 ORF 2858 2 2 2 2 2 2 2 2 2 0 ORF 3103 2 2 2 2 2 2 2 2 0 0 ORF 3184 0 0 2 2 2 0 0 2 2 0 ORF 3401 0 0 2 2 0 0 0 0 0 0 ORF 3792 2 2 2 0 2 0 0 2 2 0 ORF 3840 0 0 0 0 0 0 0 0 0 0 ORF 4101 2 2 2 2 2 2 2 2 2 0 ORF 660 2 2 0 0 0 0 0 2 0 0 ORF 757 0 0 0 0 0 0 0 0 0 0 ORF 799 0 0 0 0 0 0 0 0 0 0 ORF 817 0 0 0 0 0 0 0 0 0 0 Gene CLIP61868-1/2a CLIP87880-1/2a CLIP87881-1/2a CLIP87890-1/2a CLIP87884-1/2a CLIP87908-1/2a CLIP74902-1/2a CLIP14843-1/2a CLIP60368-1/2a CLIP69566-1/2a Lmo0017 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 Lmo0066 2 0 0 0 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 0 0 0 0 Lmo0068 0 0 0 0 0 0 0 0 0 0 Lmo0069 0 2 0 0 0 0 0 2 2 0 Lmo0071 0 2 0 0 0 0 0 2 2 0 Lmo0072 2 0 0 0 0 2 0 0 2 2 Lmo0079 2 0 2 0 2 0 0 0 2 2 Lmo0080 2 0 2 0 2 0 0 0 2 2 Lmo0081 0 0 0 0 0 0 0 0 2 2 Lmo0082 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 2 2 2 2 2 Lmo0141 0 0 2 0 2 0 0 0 0 2 Lmo0143 0 0 0 0 0 0 0 0 0 2 Lmo0144 0 0 0 0 0 0 0 0 0 2 Lmo0147 2 2 2 2 2 2 2 2 2 2 Lmo0151 0 0 0 0 0 2 0 0 0 0 Lmo0171 2 2 2 2 2 2 2 2 2 2 Lmo0172 2 2 2 2 2 2 2 2 2 2 Lmo0252 2 0 2 0 2 2 0 0 0 0 Lmo0253 2 0 2 0 2 2 0 0 0 0 Lmo0304 0 0 0 2 0 2 2 0 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 0 Lmo0320 2 2 2 0 2 0 0 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 Lmo0338 2 2 2 0 2 2 0 2 0 2 Lmo0378 2 2 2 2 2 2 2 2 2 2 Lmo0379 2 0 2 2 2 0 2 0 2 2 Lmo0380 2 2 2 2 2 2 2 2 2 2 Lmo0381 2 2 2 2 2 2 2 2 2 2 Lmo0409 0 2 2 2 2 2 2 2 2 2 Lmo0419 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 Lmo0444 0 2 0 2 0 0 2 2 0 0 Lmo0448 0 2 0 2 0 2 2 2 0 0 Lmo0459 2 0 2 0 2 0 0 0 2 2 Lmo0462 2 0 2 0 2 0 0 0 2 2 Lmo0466 0 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 0 Lmo0472 2 2 2 2 2 2 0 2 2 2 Lmo0473 2 2 2 2 2 2 0 2 2 2 Lmo0474 2 2 2 2 2 2 2 2 2 2 Lmo0493 0 2 0 2 0 2 2 2 2 2 Lmo0497 2 2 2 2 2 2 2 2 2 2 Lmo0525 2 2 2 2 2 2 2 2 2 2 Lmo0549 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 2 2 2 2 Lmo0733 2 2 2 2 2 2 2 2 2 2 Lmo0734 2 2 2 2 2 2 2 2 2 2 Lmo0735 2 2 2 2 2 2 2 2 2 2 Lmo0739 2 2 2 2 2 2 2 2 2 2 Lmo0750 2 2 2 2 2 2 2 2 2 2 Lmo0751 2 2 2 2 2 2 2 2 2 2 Lmo0752 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 Lmo0780 2 2 2 2 2 2 2 2 2 2 Lmo0801 0 2 2 2 2 0 2 2 2 2 Lmo0804 2 2 0 2 0 0 0 2 0 0 Lmo0832 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 Lmo1060 2 2 2 2 2 2 2 2 2 2 Lmo1061 2 2 2 2 2 2 2 2 2 2 Lmo1063 2 2 2 2 2 2 2 2 2 2 Lmo1076 2 2 2 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 2 2 2 Lmo1102 2 0 0 0 0 0 2 2 2 2 Lmo1115 2 0 0 0 0 0 0 2 2 2 Lmo1116 0 2 2 2 2 2 2 2 0 0 Lmo1118 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 Lmo1120 2 2 0 2 0 2 2 2 0 2 Lmo1133 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 Lmo1307 2 2 2 2 2 2 2 2 2 2 Lmo1441 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 Lmo1597 0 0 2 2 2 2 2 0 2 0 Lmo1604 2 2 2 2 2 2 2 2 2 2 Lmo1648 2 2 0 0 0 2 0 2 2 2 Lmo1666 2 2 2 2 2 2 2 2 2 2 Lmo1714 0 0 0 0 0 0 0 0 0 2 Lmo1968 2 2 2 2 2 2 2 2 2 2 Lmo1973 2 2 2 2 2 2 2 2 2 2 Lmo1974 2 2 2 2 2 2 2 2 2 2 Lmo2026 0 0 0 2 0 0 2 0 2 2 Lmo2027 2 2 2 2 2 2 2 2 2 2 Lmo2276 2 0 0 0 0 0 0 2 2 2 Lmo2277 0 0 0 2 0 2 2 2 0 0 Lmo2311 2 0 0 0 0 0 0 0 0 0 Lmo2312 0 0 2 2 0 0 0 2 2 0 Lmo2324 2 0 0 2 0 0 0 0 2 2 Lmo2408 0 0 0 2 0 0 2 0 2 0 Lmo2443 2 2 2 2 2 2 2 2 2 2 Lmo2576 2 2 2 2 2 2 2 2 2 2 Lmo2594 0 2 0 2 2 2 2 2 2 2 Lmo2595 0 2 0 0 0 2 0 2 2 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 Lmo2686 2 2 2 2 2 0 2 2 2 2 Lmo2732 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 Lmo2786 2 2 2 2 2 2 2 2 2 2 Lmo2787 2 2 2 2 2 2 2 2 2 2 Lmo2807 0 2 2 0 2 2 0 2 2 2 Lmo2809 0 2 2 2 2 2 0 2 2 2 Lmo2821 2 2 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 0 0 2 Lin0197 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 Lin0415 2 0 0 0 0 0 0 2 2 2 Lin0453 0 0 0 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 0 0 0 Lin0465 2 0 0 0 0 0 0 0 0 0 Lin0476 0 0 0 0 0 0 0 2 2 2 Lin0661 0 0 0 0 0 0 0 2 2 2 Lin0665 2 0 0 0 0 0 0 2 2 2 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0 0 0 0 0 2 2 2 ORF 2110 0 0 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 0 0 ORF 2541 2 0 2 0 2 0 0 0 0 0 ORF 2579 2 2 0 0 0 0 0 2 2 2 ORF 2777 0 0 0 0 0 0 0 0 0 0 ORF 2819 0 0 0 0 0 0 0 0 0 0 ORF 2847 0 0 2 0 2 0 0 0 0 0 ORF 2858 0 0 0 0 0 0 2 2 2 2 ORF 3103 2 2 0 2 0 0 2 2 0 2 ORF 3184 0 0 0 0 0 0 0 2 0 0 ORF 3401 0 0 0 0 0 0 0 0 0 0 ORF 3792 0 2 2 2 2 2 2 2 2 0 ORF 3840 0 0 0 0 0 0 0 0 0 0 ORF 4101 0 0 0 2 0 0 2 2 0 0 ORF 660 0 2 0 2 0 0 2 2 0 0 ORF 757 0 0 0 0 0 0 0 0 0 0 ORF 799 0 0 0 0 0 2 0 0 0 0 ORF 817 0 0 0 0 0 0 0 0 0 0 Gene CLIP80559-1/2a CLIP89458-1/2a CLIP89461-1/2a EGDe-1/2a CLIP86436-3a CLIP74905-3a CLIP8053-3a CLIP46694-1/2c Lmo0017 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 Lmo0066 0 0 2 2 0 2 0 2 Lmo0067 0 0 0 2 0 0 0 2 Lmo0068 0 0 0 2 0 0 0 2 Lmo0069 0 0 0 2 0 0 0 2 Lmo0071 0 0 0 2 0 0 0 2 Lmo0072 0 0 0 2 2 2 0 2 Lmo0079 0 2 2 2 0 2 2 2 Lmo0080 0 0 0 2 0 0 2 2 Lmo0081 0 0 0 2 0 0 0 0 Lmo0082 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 2 2 2 Lmo0141 0 2 0 2 0 0 2 2 Lmo0143 0 0 0 2 0 0 0 2 Lmo0144 0 0 0 2 0 0 0 2 Lmo0147 2 2 2 2 2 2 2 2 Lmo0151 0 0 0 2 0 0 0 2 Lmo0171 2 2 2 2 2 2 2 2 Lmo0172 2 2 2 2 2 2 2 2 Lmo0252 0 0 0 2 2 2 0 2 Lmo0253 0 0 0 2 2 2 0 2 Lmo0304 0 2 0 2 0 2 0 2 Lmo0310 0 0 0 2 0 0 0 2 Lmo0320 2 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 Lmo0338 0 2 0 2 2 2 2 2 Lmo0378 2 2 2 2 2 2 2 0 Lmo0379 2 2 2 2 2 0 2 2 Lmo0380 2 2 2 2 2 2 2 2 Lmo0381 2 2 2 2 2 2 2 2 Lmo0409 2 2 2 2 0 2 2 2 Lmo0419 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 Lmo0444 0 2 0 2 0 0 0 2 Lmo0448 0 2 0 2 0 0 0 2 Lmo0459 0 0 0 2 2 0 2 2 Lmo0462 0 0 0 2 2 0 2 2 Lmo0466 0 0 0 2 0 0 2 2 Lmo0467 0 0 0 2 0 0 2 2 Lmo0471 0 0 0 2 0 0 2 2 Lmo0472 0 0 2 2 2 2 2 2 Lmo0473 2 2 2 2 2 2 2 2 Lmo0474 2 0 2 2 2 2 2 2 Lmo0493 2 2 2 2 0 2 2 2 Lmo0497 2 2 2 2 2 2 2 2 Lmo0525 2 2 2 2 2 2 2 2 Lmo0549 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 2 2 Lmo0733 2 2 2 2 2 2 2 2 Lmo0734 2 2 2 2 2 2 2 2 Lmo0735 2 2 2 2 2 2 2 2 Lmo0739 2 2 2 2 2 2 2 2 Lmo0750 2 2 2 2 2 2 2 2 Lmo0751 2 2 2 2 2 2 2 2 Lmo0752 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 Lmo0780 2 2 2 2 2 2 2 2 Lmo0801 2 0 2 2 0 0 2 2 Lmo0804 0 0 0 2 2 2 2 2 Lmo0832 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 Lmo1060 2 2 2 2 2 2 2 2 Lmo1061 2 2 2 2 2 2 2 2 Lmo1063 2 2 2 2 2 2 2 2 Lmo1076 2 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 2 Lmo1102 2 2 2 2 2 2 2 2 Lmo1115 2 2 2 2 2 2 2 2 Lmo1116 0 0 0 2 0 2 0 2 Lmo1118 0 0 0 2 0 0 0 2 Lmo1119 0 0 0 2 0 0 0 2 Lmo1120 2 2 2 2 2 0 2 2 Lmo1133 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 Lmo1307 2 2 2 2 2 2 2 2 Lmo1441 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 Lmo1597 0 0 0 2 0 2 2 2 Lmo1604 2 2 2 2 2 2 2 2 Lmo1648 2 2 2 2 2 2 2 2 Lmo1666 2 2 2 2 2 2 2 2 Lmo1714 0 2 0 2 0 2 2 2 Lmo1968 2 2 2 2 2 2 2 2 Lmo1973 2 2 2 2 2 2 2 2 Lmo1974 2 2 2 2 2 2 2 2 Lmo2026 0 2 0 2 0 0 0 2 Lmo2027 2 2 2 2 0 2 2 2 Lmo2276 2 2 2 2 2 2 2 2 Lmo2277 2 0 2 2 2 0 0 2 Lmo2311 0 2 2 2 0 0 0 2 Lmo2312 2 2 2 2 0 0 2 2 Lmo2324 2 2 2 2 2 2 0 2 Lmo2408 0 0 2 2 0 0 2 2 Lmo2443 0 2 0 2 2 2 2 2 Lmo2576 2 2 2 2 2 2 2 2 Lmo2594 2 2 2 2 0 2 2 2 Lmo2595 2 2 2 2 0 2 2 2 Lmo2671 2 2 2 2 2 2 2 2 Lmo2686 2 2 2 2 2 0 2 2 Lmo2732 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 Lmo2786 2 2 2 2 2 2 2 2 Lmo2787 2 2 2 2 2 2 2 2 Lmo2807 2 0 2 2 0 0 2 2 Lmo2809 2 0 2 2 0 2 0 2 Lmo2821 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 0 Lin0197 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 Lin0415 2 2 2 0 2 2 2 2 Lin0453 0 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 0 Lin0465 0 0 0 0 2 2 0 0 Lin0476 0 2 2 0 2 0 2 0 Lin0661 0 2 2 0 2 0 0 0 Lin0665 2 2 2 0 0 2 0 2 Lin0677 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 Lin0740 2 2 2 0 2 2 2 2 Lin0803 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 Lin1073 0 0 0 0 0 0 0 0 Lin1083 0 0 0 0 2 0 0 0 Lin1084 2 0 2 2 2 0 2 0 Lin1090 0 0 0 0 0 0 0 0 Lin1204 0 0 0 0 0 0 0 0 Lin1262 2 2 2 0 2 2 2 2 Lin1299 2 2 2 0 2 2 2 2 Lin1328 2 2 2 0 2 2 2 2 Lin1452 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 Lin2397 0 2 0 0 2 2 2 0 Lin2494 2 0 2 2 2 2 2 2 Lin2603 0 2 2 2 0 0 2 2 Lin2724 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 Lin2743 0 0 0 2 2 0 0 0 Lin2744 0 0 2 2 2 0 0 2 Lin2839 2 0 2 0 0 0 0 0 Lin2918 0 0 0 0 0 0 0 0 ORF 105 0 0 0 0 0 0 0 0 ORF 1390 0 0 2 2 0 2 0 0 ORF 1445 0 0 0 0 0 0 0 0 ORF 1490 0 0 0 0 0 0 0 0 ORF 1491 0 0 0 0 0 0 0 0 ORF 1590 2 2 2 2 2 2 2 0 ORF 1761 0 0 0 0 0 0 0 0 ORF 2017 0 0 2 0 0 0 0 0 ORF 2074 0 2 0 0 2 0 2 0 ORF 2076 0 2 0 0 2 0 2 0 ORF 2110 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 ORF 2541 0 0 0 0 2 0 0 0 ORF 2579 0 2 2 0 2 0 2 0 ORF 2777 2 2 2 0 0 0 0 0 ORF 2819 0 0 0 0 0 0 0 0 ORF 2847 0 0 0 0 0 0 0 0 ORF 2858 2 2 2 2 2 2 2 2 ORF 3103 0 2 0 2 2 2 0 0 ORF 3184 0 0 2 0 0 0 0 0 ORF 3401 0 0 2 0 0 0 0 0 ORF 3792 2 2 2 2 0 0 0 2 ORF 3840 0 0 0 0 0 0 0 0 ORF 4101 2 2 2 2 0 0 0 2 ORF 660 0 0 0 2 0 2 0 0 ORF 757 0 0 2 0 0 0 0 0 ORF 799 0 0 0 0 0 2 0 0 ORF 817 0 0 0 0 0 0 0 0 CLIP42653- CLIP87892- Gene CLIP85412-3c CLIP42972-1/2c 1/2c CLIP2710-1/2c CLIP87891-1/2c 1/2c CLIP87893-1/2c CLIP11550-1/2c LO028-1/2c CLIP11962-3c CLIP74907 3c Lmo0017 2 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 2 Lmo0066 2 2 2 2 2 2 2 2 2 2 2 Lmo0067 2 2 2 2 2 2 2 2 2 2 2 Lmo0068 2 2 2 2 2 2 2 2 2 2 2 Lmo0069 2 2 2 2 2 2 2 2 2 2 2 Lmo0071 2 2 2 2 2 2 2 2 2 2 2 Lmo0072 2 2 2 2 2 2 2 2 2 2 2 Lmo0079 2 0 2 2 2 2 2 2 2 2 2 Lmo0080 2 2 2 2 2 2 2 2 2 2 2 Lmo0081 2 2 2 2 2 2 2 2 2 2 2 Lmo0082 2 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 2 2 2 2 2 2 Lmo0141 2 2 2 2 2 2 2 2 2 2 2 Lmo0143 2 2 2 2 2 2 2 2 2 2 2 Lmo0144 2 2 2 2 2 2 2 2 2 2 2 Lmo0147 2 2 2 2 2 2 2 2 2 2 2 Lmo0151 2 2 2 2 2 2 2 2 2 2 2 Lmo0171 2 2 2 2 2 2 2 2 2 2 2 Lmo0172 2 2 2 2 2 2 2 2 2 2 2 Lmo0252 2 2 2 2 2 2 2 2 2 2 2 Lmo0253 2 2 2 2 2 2 2 2 2 2 2 Lmo0304 2 2 2 2 2 2 2 2 2 2 2 Lmo0310 2 2 2 2 2 2 2 2 2 2 2 Lmo0320 2 2 2 2 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 2 Lmo0338 2 2 2 2 2 2 2 2 2 2 2 Lmo0378 2 2 2 2 2 2 2 2 2 2 2 Lmo0379 2 2 2 2 2 2 2 2 2 2 2 Lmo0380 2 0 2 2 2 2 2 2 2 2 2 Lmo0381 2 2 2 2 2 2 2 2 2 2 2 Lmo0409 2 2 2 2 2 2 2 2 2 2 2 Lmo0419 2 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 2 Lmo0444 2 2 2 2 2 2 2 2 2 2 2 Lmo0448 2 2 2 2 2 2 2 2 2 2 2 Lmo0459 2 2 2 2 2 2 2 2 2 2 2 Lmo0462 2 0 2 2 2 2 2 2 2 2 2 Lmo0466 2 2 2 2 2 2 2 2 2 2 2 Lmo0467 2 2 2 2 2 2 2 2 2 2 2 Lmo0471 2 2 2 2 2 2 2 2 2 2 2 Lmo0472 2 2 2 2 2 2 2 2 2 2 2 Lmo0473 2 2 2 2 2 2 2 2 2 2 2 Lmo0474 2 2 2 2 2 2 2 2 2 2 2 Lmo0493 2 2 2 2 2 2 2 2 2 2 2 Lmo0497 2 2 2 2 2 2 2 2 2 2 2 Lmo0525 2 2 2 2 2 2 2 2 2 2 2 Lmo0549 2 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 2 2 2 2 2 Lmo0733 2 2 2 2 2 2 2 2 2 2 2 Lmo0734 2 2 2 2 2 2 2 2 2 2 2 Lmo0735 2 2 2 2 2 2 2 2 2 2 2 Lmo0739 2 2 2 2 2 2 2 2 2 2 2 Lmo0750 2 2 2 2 2 2 2 2 2 2 2 Lmo0751 2 2 2 2 2 2 2 2 2 2 2 Lmo0752 2 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 2 Lmo0780 2 2 2 2 2 2 2 2 2 2 2 Lmo0801 2 2 2 2 2 2 2 2 2 2 2 Lmo0804 2 2 2 2 2 2 2 2 2 2 2 Lmo0832 2 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 2 Lmo1060 2 2 2 2 2 2 2 2 2 2 2 Lmo1061 2 2 2 2 2 2 2 2 2 2 2 Lmo1063 2 2 2 2 2 2 2 2 2 2 2 Lmo1076 2 2 2 2 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 2 2 2 2 Lmo1102 2 2 2 2 2 2 2 2 2 2 2 Lmo1115 2 2 2 2 0 0 0 2 2 2 2 Lmo1116 2 2 2 2 2 2 2 2 2 2 2 Lmo1118 2 2 2 2 2 2 2 2 2 2 2 Lmo1119 2 2 2 2 2 2 2 2 2 2 2 Lmo1120 2 2 2 2 2 2 2 2 2 2 2 Lmo1133 2 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 2 Lmo1307 2 2 2 2 2 2 2 2 2 2 2 Lmo1441 2 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 2 Lmo1597 2 2 2 2 2 2 2 2 2 2 2 Lmo1604 2 2 2 2 2 2 2 2 2 2 2 Lmo1648 2 2 2 2 2 2 2 2 2 2 2 Lmo1666 2 2 2 2 2 2 2 2 2 2 2 Lmo1714 2 2 2 2 2 2 2 2 2 2 2 Lmo1968 2 2 2 2 2 2 2 2 2 2 2 Lmo1973 2 2 2 2 2 2 2 2 2 2 2 Lmo1974 2 2 2 2 2 2 2 2 2 2 2 Lmo2026 2 2 2 2 2 2 2 2 2 2 2 Lmo2027 2 2 2 2 2 2 2 2 2 2 2 Lmo2276 2 2 2 2 0 0 0 2 2 2 2 Lmo2277 0 0 0 0 0 2 2 0 2 0 2 Lmo2311 2 0 2 2 0 2 2 2 2 2 0 Lmo2312 2 2 2 2 2 0 0 0 2 2 2 Lmo2324 0 0 2 2 2 2 2 2 2 2 2 Lmo2408 2 2 2 2 2 2 2 2 2 2 2 Lmo2443 2 2 2 2 2 2 2 2 2 2 2 Lmo2576 2 2 2 2 2 2 2 2 2 2 2 Lmo2594 2 0 2 2 2 2 2 2 2 2 2 Lmo2595 2 2 2 2 2 2 2 2 2 2 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 2 Lmo2686 2 2 2 2 2 2 2 2 2 2 2 Lmo2732 2 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 2 Lmo2786 2 2 2 2 2 2 2 2 2 2 2 Lmo2787 2 2 2 2 2 2 2 2 2 2 2 Lmo2807 2 2 2 2 2 2 2 2 2 2 2 Lmo2809 2 0 2 2 2 2 2 2 2 2 2 Lmo2821 2 2 2 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 0 0 0 0 Lin0197 0 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 0 Lin0415 2 2 2 2 0 0 0 2 2 2 2 Lin0453 0 0 0 0 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 0 0 0 0 Lin0465 0 0 0 0 0 0 0 0 0 0 0 Lin0476 2 2 2 2 0 0 0 2 2 2 2 Lin0661 2 2 2 2 0 0 0 0 2 0 2 Lin0665 2 2 0 2 0 0 0 0 2 2 2 Lin0677 0 0 0 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 0 Lin0740 2 2 2 2 0 0 0 2 2 2 2 Lin0803 0 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 0 Lin1073 0 0 0 0 0 0 0 0 0 0 0 Lin1083 0 0 0 0 0 0 0 0 0 0 0 Lin1084 0 0 0 0 0 0 0 0 0 0 0 Lin1090 0 0 0 0 0 0 0 0 0 0 0 Lin1204 0 0 0 0 0 0 0 0 0 0 0 Lin1262 2 2 2 2 0 0 0 2 2 2 2 Lin1299 2 2 2 2 0 2 2 2 2 2 2 Lin1328 2 2 2 2 0 0 0 2 2 2 2 Lin1452 0 0 0 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 0 0 0 Lin2397 0 0 0 0 2 2 2 0 2 0 0 Lin2494 2 2 2 2 2 2 2 2 2 2 2 Lin2603 0 0 2 2 2 0 0 0 2 2 0 Lin2724 0 0 0 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 0 0 0 Lin2743 0 0 0 0 0 0 0 0 0 0 0 Lin2744 2 2 2 2 0 0 0 0 2 2 2 Lin2839 0 0 0 0 0 0 0 0 0 0 0 Lin2918 0 0 0 0 0 0 0 0 0 0 0 ORF 105 0 0 0 0 0 0 0 0 0 0 0 ORF 1390 0 0 0 0 0 2 0 0 0 0 0 ORF 1445 0 0 0 0 0 0 0 0 0 0 0 ORF 1490 0 0 0 0 0 0 0 0 0 0 0 ORF 1491 0 0 0 0 0 0 0 0 0 0 0 ORF 1590 0 0 0 0 0 0 0 0 0 0 0 ORF 1761 0 0 0 0 0 0 0 0 0 0 0 ORF 2017 0 0 0 0 0 0 0 0 0 0 0 ORF 2074 0 0 0 0 0 0 0 0 0 0 0 ORF 2076 0 0 0 0 0 0 0 0 0 0 0 ORF 2110 0 0 0 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 0 0 0 ORF 2541 0 0 0 0 0 0 0 0 0 0 0 ORF 2579 0 0 0 0 0 0 0 0 0 0 0 ORF 2777 0 0 0 0 0 0 0 0 0 0 0 ORF 2819 0 0 0 0 0 0 0 0 0 0 0 ORF 2847 0 0 0 0 0 0 0 0 0 0 0 ORF 2858 0 2 2 2 0 2 0 2 2 2 2 ORF 3103 0 0 0 0 0 0 0 0 0 0 0 ORF 3184 0 2 0 0 0 2 2 0 0 2 0 ORF 3401 0 0 0 0 0 0 0 0 0 0 0 ORF 3792 0 0 0 0 0 2 0 0 0 0 0 ORF 3840 0 0 0 0 0 0 0 0 0 0 0 ORF 4101 0 2 0 2 0 2 0 0 0 2 0 ORF 660 0 0 0 0 0 0 0 0 0 0 0 ORF 757 0 0 0 0 0 0 0 0 0 0 0 ORF 799 0 0 0 0 0 0 0 0 0 0 0 ORF 817 0 0 0 0 0 0 0 0 0 0 0 Gene CLIP61839-1/2a CLIP42655-1/2b CLIP3559-1/2b CLIP46686-1/2b CLIP989-1/2b CLIP87878-1/2b CLIP87879-1/2b CLIP87888-1/2b CLIP87897-1/2b CLIP87909-1/2b Lmo0017 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 Lmo0066 2 0 2 2 2 0 0 0 0 0 Lmo0067 2 0 0 2 2 0 0 0 0 0 Lmo0068 2 0 2 2 2 0 0 2 0 0 Lmo0069 0 0 2 2 2 0 2 2 2 0 Lmo0071 0 2 2 2 2 2 2 2 2 0 Lmo0072 2 2 2 2 2 2 2 2 2 0 Lmo0079 2 2 2 2 2 2 2 2 2 2 Lmo0080 2 2 2 2 2 2 2 2 0 2 Lmo0081 2 0 2 0 0 0 2 0 0 0 Lmo0082 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 Lmo0106 2 0 2 0 0 0 2 0 0 2 Lmo0141 2 0 0 2 2 0 2 0 0 2 Lmo0143 0 0 0 0 0 0 0 0 0 2 Lmo0144 0 0 0 2 2 0 2 0 0 2 Lmo0147 2 2 0 2 2 0 2 0 0 0 Lmo0151 0 0 0 0 0 0 0 0 0 0 Lmo0171 2 0 0 0 0 0 0 0 0 0 Lmo0172 2 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 0 0 0 0 Lmo0304 0 2 2 0 0 2 2 2 2 2 Lmo0310 0 0 2 0 0 0 0 0 0 2 Lmo0320 2 2 2 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 Lmo0338 0 0 0 0 0 0 0 0 0 0 Lmo0378 2 2 0 2 2 2 2 2 2 2 Lmo0379 2 0 0 0 0 0 0 0 0 0 Lmo0380 2 2 0 2 2 2 2 2 2 2 Lmo0381 2 2 0 2 2 2 2 2 2 2 Lmo0409 2 2 0 0 2 0 0 0 2 0 Lmo0419 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 Lmo0444 2 2 0 0 0 2 2 2 2 2 Lmo0448 2 2 2 0 2 2 2 2 2 2 Lmo0459 0 2 2 2 2 2 2 2 2 2 Lmo0462 0 2 2 2 2 2 2 2 2 2 Lmo0466 0 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 0 Lmo0472 2 0 0 2 2 0 0 2 2 2 Lmo0473 0 0 0 0 0 0 2 0 0 2 Lmo0474 2 0 0 0 0 0 2 0 0 0 Lmo0493 2 2 2 2 2 2 2 2 2 2 Lmo0497 2 2 2 2 2 2 2 2 2 2 Lmo0525 2 0 0 0 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 0 2 Lmo0631 2 2 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 2 2 0 0 Lmo0733 2 2 2 2 2 2 2 2 2 2 Lmo0734 2 0 0 0 0 0 0 0 0 0 Lmo0735 2 0 0 0 0 0 0 0 0 0 Lmo0739 2 0 0 0 0 0 0 0 0 0 Lmo0750 2 0 0 0 0 0 0 0 0 0 Lmo0751 2 2 0 0 0 2 2 2 2 0 Lmo0752 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 Lmo0780 2 0 0 0 0 0 0 0 0 0 Lmo0801 2 0 0 0 0 0 0 0 0 0 Lmo0804 0 0 0 2 2 2 2 2 0 2 Lmo0832 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 Lmo1060 2 0 0 0 0 0 0 0 0 0 Lmo1061 2 0 0 0 0 0 0 0 0 0 Lmo1063 2 0 0 0 0 0 0 0 0 0 Lmo1076 2 2 2 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 2 2 2 Lmo1102 2 2 2 2 2 0 0 0 2 0 Lmo1115 2 0 0 2 2 0 0 0 0 0 Lmo1116 0 2 0 0 0 2 2 2 2 0 Lmo1118 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 Lmo1120 0 2 2 2 2 2 2 2 2 0 Lmo1133 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 Lmo1307 2 0 0 0 0 0 0 0 0 0 Lmo1441 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 Lmo1597 2 2 2 2 2 2 0 2 2 0 Lmo1604 2 2 2 2 2 0 0 2 2 2 Lmo1648 2 2 0 2 0 0 0 0 0 0 Lmo1666 2 2 2 2 2 2 2 2 2 2 Lmo1714 0 2 2 2 2 2 2 2 2 2 Lmo1968 2 0 0 0 0 0 0 0 0 0 Lmo1973 2 0 0 0 0 0 0 0 0 0 Lmo1974 2 0 0 0 0 0 0 0 0 0 Lmo2026 2 0 0 0 0 0 0 0 0 0 Lmo2027 2 2 2 2 2 2 2 2 0 2 Lmo2276 2 2 2 2 2 2 0 0 0 2 Lmo2277 2 0 0 0 0 0 0 0 0 0 Lmo2311 2 0 0 0 0 0 0 0 0 0 Lmo2312 2 2 2 2 2 2 2 2 0 2 Lmo2324 2 0 0 2 2 2 2 0 0 0 Lmo2408 2 0 0 0 0 0 0 0 0 0 Lmo2443 2 2 2 2 2 2 2 2 0 2 Lmo2576 2 0 0 0 0 0 0 0 0 0 Lmo2594 2 2 2 0 2 2 2 0 0 2 Lmo2595 0 0 2 0 0 0 2 0 0 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 Lmo2686 2 0 0 0 0 0 0 0 0 2 Lmo2732 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 Lmo2786 2 0 0 0 0 0 0 0 0 0 Lmo2787 2 0 0 0 0 0 0 0 0 0 Lmo2807 2 0 0 0 0 0 0 2 0 0 Lmo2809 2 2 2 2 2 2 2 2 2 2 Lmo2821 2 2 2 2 2 2 2 2 2 2 Lin0060 2 0 0 2 2 0 0 0 0 2 Lin0197 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 Lin0415 2 2 2 2 2 2 0 2 0 2 Lin0453 0 0 0 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 0 0 0 Lin0465 0 0 0 0 0 0 0 0 0 0 Lin0476 2 2 2 2 2 0 0 0 0 0 Lin0661 2 0 0 0 0 0 0 0 0 0 Lin0665 2 2 2 2 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 Lin0740 2 2 2 2 2 0 0 0 0 0 Lin0803 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 Lin1073 0 0 0 0 0 0 0 0 0 0 Lin1083 0 0 2 2 2 0 0 0 0 0 Lin1084 0 2 2 2 2 2 2 2 2 2 Lin1090 0 2 2 2 2 2 2 2 2 2 Lin1204 0 2 2 2 2 2 2 0 2 2 Lin1262 2 2 2 2 2 0 0 0 0 0 Lin1299 2 2 2 2 2 2 0 0 2 0 Lin1328 2 2 2 2 2 0 0 0 0 0 Lin1452 0 0 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 0 0 Lin2397 2 0 0 2 2 0 2 0 0 2 Lin2494 2 2 2 2 2 2 2 2 2 2 Lin2603 0 0 2 2 0 0 0 0 0 0 Lin2724 0 0 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 0 0 Lin2743 2 2 0 2 2 2 0 2 2 0 Lin2744 2 2 2 2 2 2 0 2 2 0 Lin2839 0 0 2 0 0 0 0 0 0 2 Lin2918 0 0 0 0 0 0 0 0 0 0 ORF 105 0 2 2 0 0 2 0 2 2 0 ORF 1390 0 0 0 0 0 0 0 0 0 0 ORF 1445 0 0 0 0 0 0 0 0 0 0 ORF 1490 0 2 2 2 2 2 2 2 2 2 ORF 1491 0 2 2 2 2 2 2 2 2 2 ORF 1590 2 2 2 2 2 2 2 2 2 2 ORF 1761 0 2 2 2 2 2 2 2 2 2 ORF 2017 0 2 2 2 2 2 2 2 2 2 ORF 2074 2 2 2 2 2 2 2 2 2 2 ORF 2076 2 2 2 2 2 2 2 2 2 2 ORF 2110 0 0 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 0 0 ORF 2541 0 2 2 2 2 2 2 2 2 2 ORF 2579 2 2 2 2 2 2 2 2 2 2 ORF 2777 0 2 2 2 2 2 2 2 2 2 ORF 2819 0 2 2 2 2 2 2 2 2 2 ORF 2847 0 0 0 0 0 0 0 0 0 0 ORF 2858 2 2 2 2 2 2 2 2 2 0 ORF 3103 0 2 0 0 0 2 0 2 2 0 ORF 3184 0 2 0 0 2 2 2 2 2 0 ORF 3401 0 2 0 0 2 0 0 0 0 0 ORF 3792 0 2 2 2 2 2 2 2 2 2 ORF 3840 0 2 2 2 2 2 2 2 2 2 ORF 4101 2 2 2 0 2 2 2 2 2 2 ORF 660 0 0 0 0 0 0 2 0 0 0 ORF 757 0 0 2 0 0 0 2 0 0 0 ORF 799 0 0 0 0 0 0 0 0 0 0 ORF 817 0 2 2 2 2 2 2 2 2 0 Gene CLIP87910-1/2b CLIP14842-1/2b CLIP70086-1/2b CLIP70848-1/2b CLIP76278-1/2b CLIP89460-1/2b CLIP74906-3b Lmo0017 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 Lmo0066 0 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 0 Lmo0068 2 0 2 0 2 2 0 Lmo0069 2 2 2 2 2 2 2 Lmo0071 2 2 2 2 2 2 2 Lmo0072 2 2 2 2 2 2 2 Lmo0079 2 2 2 2 2 2 2 Lmo0080 2 2 2 2 2 2 2 Lmo0081 2 0 2 0 2 2 0 Lmo0082 2 2 2 2 2 2 0 Lmo0083 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 Lmo0106 0 0 2 0 2 2 0 Lmo0141 0 0 0 0 0 0 0 Lmo0143 0 0 0 0 0 0 0 Lmo0144 0 0 0 0 0 0 0 Lmo0147 0 2 2 2 2 2 2 Lmo0151 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 0 Lmo0304 2 2 2 2 2 2 2 Lmo0310 2 0 2 0 2 2 0 Lmo0320 2 2 0 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 Lmo0338 0 0 0 0 0 0 0 Lmo0378 0 2 0 2 0 0 2 Lmo0379 0 0 0 0 0 0 0 Lmo0380 0 2 0 2 0 0 2 Lmo0381 0 2 0 2 0 0 2 Lmo0409 0 2 2 2 2 2 2 Lmo0419 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 Lmo0444 0 2 0 2 0 0 2 Lmo0448 2 2 2 2 2 2 2 Lmo0459 2 2 2 2 2 2 2 Lmo0462 2 2 2 2 2 2 2 Lmo0466 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 Lmo0472 0 0 0 0 0 0 0 Lmo0473 0 0 0 0 2 2 0 Lmo0474 0 0 0 0 0 0 0 Lmo0493 2 2 2 2 2 2 2 Lmo0497 2 2 2 2 2 2 2 Lmo0525 0 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 Lmo0732 2 2 2 2 2 2 0 Lmo0733 2 2 2 2 2 2 2 Lmo0734 0 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 Lmo0750 0 0 0 0 0 0 0 Lmo0751 0 2 0 2 0 0 2 Lmo0752 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 Lmo0780 0 0 2 0 0 0 0 Lmo0801 0 0 0 0 0 0 0 Lmo0804 2 0 0 0 0 0 0 Lmo0832 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 2 2 Lmo1030 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 Lmo1060 0 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 0 Lmo1076 2 2 2 2 2 2 2 Lmo1077 2 2 2 2 2 2 2 Lmo1080 2 2 2 2 2 2 2 Lmo1081 2 2 2 2 2 2 2 Lmo1082 2 2 2 2 2 2 2 Lmo1085 2 2 2 2 2 2 2 Lmo1088 2 2 2 2 2 2 2 Lmo1090 2 2 2 2 2 2 2 Lmo1091 2 2 2 2 2 2 2 Lmo1102 2 2 2 2 2 2 0 Lmo1115 0 0 0 0 0 0 0 Lmo1116 0 2 0 2 0 0 2 Lmo1118 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 Lmo1120 2 2 2 2 2 2 2 Lmo1133 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 Lmo1307 0 0 0 0 0 0 0 Lmo1441 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 Lmo1597 2 2 2 2 2 2 2 Lmo1604 2 2 2 2 2 2 0 Lmo1648 0 0 0 2 0 0 2 Lmo1666 2 2 2 2 2 2 2 Lmo1714 2 2 2 2 2 2 2 Lmo1968 0 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 Lmo2027 2 2 2 2 2 2 0 Lmo2276 2 2 2 2 2 2 0 Lmo2277 0 0 0 0 0 0 0 Lmo2311 0 0 0 0 0 2 0 Lmo2312 2 0 2 0 2 2 2 Lmo2324 2 0 2 0 0 0 0 Lmo2408 0 0 0 0 0 0 0 Lmo2443 2 2 2 2 2 2 2 Lmo2576 0 0 0 0 0 0 0 Lmo2594 2 2 2 2 2 2 0 Lmo2595 2 0 2 0 2 2 0 Lmo2671 2 2 2 2 2 2 2 Lmo2686 0 0 0 0 0 0 0 Lmo2732 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 Lmo2786 0 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 0 Lmo2807 0 0 0 0 0 0 0 Lmo2809 2 2 2 2 2 2 2 Lmo2821 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 Lin0197 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 Lin0415 2 2 2 2 2 2 0 Lin0453 0 0 0 0 0 0 0 Lin0454 0 0 0 0 0 0 0 Lin0455 0 0 0 0 0 0 0 Lin0465 0 0 0 0 0 0 0 Lin0476 0 0 2 0 2 2 0 Lin0661 0 0 0 0 0 2 0 Lin0665 2 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 Lin0740 0 2 2 2 0 2 0 Lin0803 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 Lin1073 0 0 0 0 0 0 0 Lin1083 2 0 2 0 2 2 0 Lin1084 2 2 2 2 2 2 2 Lin1090 2 2 2 2 2 2 2 Lin1204 0 2 2 2 2 2 2 Lin1262 0 2 2 2 2 2 0 Lin1299 2 2 2 2 2 2 2 Lin1328 0 2 2 2 2 2 0 Lin1452 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 Lin2397 0 0 0 0 2 0 0 Lin2494 2 2 2 2 2 2 2 Lin2603 2 0 0 0 0 2 0 Lin2724 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 Lin2743 0 2 2 2 0 2 2 Lin2744 0 2 2 2 0 2 2 Lin2839 0 0 2 0 2 2 0 Lin2918 0 0 0 0 0 0 0 ORF 105 2 2 2 2 2 2 2 ORF 1390 0 0 0 2 0 2 0 ORF 1445 0 0 0 0 0 0 0 ORF 1490 2 2 2 2 2 2 2 ORF 1491 2 2 2 2 2 2 2 ORF 1590 0 2 2 2 2 2 2 ORF 1761 2 2 2 2 2 2 2 ORF 2017 2 2 2 2 2 2 2 ORF 2074 2 2 2 2 2 2 2 ORF 2076 2 2 2 2 2 2 2 ORF 2110 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 ORF 2541 2 2 2 2 2 2 2 ORF 2579 0 2 2 2 2 2 2 ORF 2777 2 2 2 2 2 2 2 ORF 2819 2 2 2 2 2 2 2 ORF 2847 0 0 0 0 0 0 0 ORF 2858 0 2 2 2 2 2 2 ORF 3103 0 2 0 2 0 0 2 ORF 3184 0 2 0 2 0 2 2 ORF 3401 0 2 2 2 2 2 0 ORF 3792 2 2 2 2 2 2 2 ORF 3840 2 2 2 2 2 2 2 ORF 4101 2 2 2 2 2 2 2 ORF 660 0 0 0 0 0 0 0 ORF 757 2 0 2 0 2 2 0 ORF 799 0 0 0 0 0 0 0 ORF 817 2 2 2 2 2 2 2 CLIP42635- Gene CLIP87900-3b CLIP3558-3b CLIP74917-7 CLIP61673-7 4b Epi CLIP42646-4b Epi CLIP46679-4b CLIP2698-4b CLIP27993-4b CLIP4598-4b CLIP46684-4b Lmo0017 2 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 2 Lmo0066 0 0 0 0 0 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 0 0 0 0 0 Lmo0068 2 0 0 0 2 2 2 0 2 2 2 Lmo0069 0 2 2 2 2 2 2 0 2 2 2 Lmo0071 2 2 2 2 2 2 2 0 2 2 2 Lmo0072 2 2 2 0 2 2 2 2 2 2 2 Lmo0079 2 2 2 2 2 2 2 2 2 2 2 Lmo0080 2 2 2 2 2 2 2 2 2 2 2 Lmo0081 0 0 0 2 0 0 0 0 0 0 0 Lmo0082 2 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 2 Lmo0106 0 0 0 2 2 2 2 2 2 2 2 Lmo0141 0 0 0 2 2 2 2 2 2 2 2 Lmo0143 0 0 0 0 0 0 0 0 0 0 0 Lmo0144 0 0 0 2 2 2 2 2 2 2 2 Lmo0147 2 2 0 2 2 2 2 2 2 2 2 Lmo0151 0 0 0 0 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 0 0 0 0 0 Lmo0304 2 2 2 2 0 0 0 0 0 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 0 0 Lmo0320 2 2 2 0 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 2 Lmo0338 0 0 0 0 0 0 0 0 0 0 0 Lmo0378 2 2 2 2 0 0 0 0 0 0 0 Lmo0379 0 0 0 0 0 0 0 0 0 0 0 Lmo0380 2 2 2 2 0 0 0 0 0 0 0 Lmo0381 2 2 2 2 0 0 0 0 0 0 0 Lmo0409 0 2 2 2 2 2 2 2 0 0 0 Lmo0419 2 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 2 Lmo0444 2 2 2 2 0 0 0 0 0 0 0 Lmo0448 2 2 2 2 2 2 2 2 2 0 2 Lmo0459 2 2 2 2 2 2 2 2 2 2 2 Lmo0462 2 2 2 2 2 2 2 2 2 2 2 Lmo0466 0 0 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 0 0 Lmo0472 0 0 0 0 0 0 0 0 0 0 0 Lmo0473 0 0 0 0 2 2 2 0 2 0 0 Lmo0474 0 0 0 2 2 2 2 2 2 2 2 Lmo0493 2 2 2 2 2 2 2 2 2 2 2 Lmo0497 2 2 2 2 0 0 0 0 0 0 0 Lmo0525 0 0 0 0 0 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 2 2 2 2 2 2 2 2 Lmo0631 2 2 2 2 2 2 2 2 2 2 2 Lmo0632 2 2 2 2 2 2 2 2 2 2 2 Lmo0732 2 2 0 2 2 2 2 2 2 0 2 Lmo0733 2 2 2 2 2 2 2 2 2 2 2 Lmo0734 0 0 0 0 0 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 0 0 0 0 Lmo0750 0 0 0 0 2 0 0 0 0 0 0 Lmo0751 2 2 2 2 2 2 2 2 2 2 2 Lmo0752 2 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 2 Lmo0780 0 2 0 2 2 2 0 0 0 0 0 Lmo0801 0 0 0 0 2 2 2 0 0 0 0 Lmo0804 0 2 2 0 2 2 2 0 0 0 0 Lmo0832 2 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 2 Lmo0842 0 2 2 2 2 2 2 0 2 0 0 Lmo1030 2 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 2 Lmo1060 0 0 0 0 0 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 0 0 0 0 0 Lmo1076 2 2 2 2 0 0 0 0 0 0 0 Lmo1077 2 2 2 2 0 0 0 0 0 0 0 Lmo1080 2 2 2 2 0 0 0 0 0 0 0 Lmo1081 2 2 2 2 0 0 0 0 0 0 0 Lmo1082 2 2 2 2 0 0 0 0 0 0 0 Lmo1085 2 2 2 2 0 0 0 0 0 0 0 Lmo1088 2 2 2 2 0 0 0 0 0 0 0 Lmo1090 2 2 2 2 0 0 0 0 0 0 0 Lmo1091 2 2 2 2 0 0 0 0 0 0 0 Lmo1102 2 2 0 0 2 2 2 2 2 2 2 Lmo1115 0 0 0 0 0 0 0 0 0 0 0 Lmo1116 2 2 2 2 2 2 2 0 2 2 2 Lmo1118 0 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 0 Lmo1120 2 2 2 2 2 2 2 2 2 2 2 Lmo1133 2 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 2 Lmo1307 0 0 0 0 0 0 0 0 0 0 0 Lmo1441 2 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 2 Lmo1597 2 2 2 0 0 0 0 0 0 0 0 Lmo1604 0 2 0 2 2 2 2 2 2 2 2 Lmo1648 0 0 0 0 2 0 0 0 0 0 0 Lmo1666 2 2 2 2 2 2 2 2 2 2 2 Lmo1714 2 2 2 2 2 2 2 2 2 2 2 Lmo1968 0 0 0 0 0 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 0 0 0 0 Lmo2027 0 2 0 0 2 2 2 2 2 0 0 Lmo2276 2 2 0 0 2 2 2 2 2 2 0 Lmo2277 2 2 0 0 2 0 2 0 0 0 0 Lmo2311 0 0 0 0 0 0 0 0 0 0 0 Lmo2312 2 2 0 2 0 0 2 2 0 0 2 Lmo2324 0 0 0 2 0 0 2 2 0 2 2 Lmo2408 0 0 0 0 0 0 0 0 0 0 0 Lmo2443 2 2 2 2 2 2 2 2 2 2 2 Lmo2576 0 0 0 0 0 0 0 0 0 0 0 Lmo2594 2 2 2 2 2 2 2 2 2 2 2 Lmo2595 0 0 0 2 2 2 2 2 2 2 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 2 Lmo2686 0 0 0 0 0 0 0 0 0 0 0 Lmo2732 2 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 2 Lmo2786 0 0 0 0 0 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 0 0 0 0 0 Lmo2807 2 0 0 2 2 2 2 0 2 0 0 Lmo2809 2 2 2 2 0 0 0 2 0 0 0 Lmo2821 2 2 2 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 2 0 0 0 Lin0197 0 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 0 Lin0415 0 2 0 0 2 2 2 2 2 2 2 Lin0453 0 0 0 0 2 2 2 2 2 2 2 Lin0454 0 0 0 0 2 2 2 2 2 2 2 Lin0455 0 0 0 0 2 2 2 0 2 0 2 Lin0465 0 0 0 0 0 0 0 0 0 0 0 Lin0476 0 2 0 0 2 2 0 0 2 0 0 Lin0661 0 0 0 0 2 2 0 0 2 0 0 Lin0665 2 2 2 2 2 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 0 Lin0740 0 0 0 0 2 2 2 0 2 0 0 Lin0803 0 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 0 Lin1073 0 0 0 0 2 2 2 2 2 2 2 Lin1083 0 0 0 0 0 0 0 0 0 0 0 Lin1084 2 2 2 2 2 2 2 2 2 2 2 Lin1090 2 2 2 2 2 2 2 2 2 2 2 Lin1204 2 2 2 2 2 2 2 2 2 2 2 Lin1262 0 2 0 0 2 2 2 2 2 2 2 Lin1299 2 0 0 0 2 2 2 0 2 2 2 Lin1328 0 2 0 0 2 2 2 2 2 2 2 Lin1452 0 0 0 2 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 0 0 0 Lin2397 0 0 0 2 0 0 2 0 0 0 0 Lin2494 2 2 2 0 0 2 2 0 0 0 0 Lin2603 2 2 0 0 0 0 0 0 0 0 2 Lin2724 0 0 0 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 0 0 0 Lin2743 2 2 2 0 0 0 0 0 0 0 0 Lin2744 2 2 2 0 0 0 0 2 0 0 0 Lin2839 0 0 0 0 0 0 0 0 0 0 0 Lin2918 0 0 0 0 0 0 0 0 0 0 0 ORF 105 2 2 2 0 2 2 2 0 2 2 2 ORF 1390 2 0 0 0 2 2 2 0 0 2 0 ORF 1445 0 0 0 0 2 2 2 2 2 2 2 ORF 1490 2 2 2 2 2 2 2 2 2 2 2 ORF 1491 2 2 2 2 2 2 2 2 2 2 2 ORF 1590 2 2 2 2 2 2 2 2 2 2 2 ORF 1761 2 2 2 2 2 2 2 2 2 2 2 ORF 2017 2 2 2 2 2 2 2 2 2 2 2 ORF 2074 2 2 2 2 2 2 2 2 2 2 2 ORF 2076 2 2 2 2 2 2 2 2 2 2 2 ORF 2110 0 0 0 0 2 2 2 2 2 2 2 ORF 2372 0 0 0 0 2 2 2 2 2 2 2 ORF 2541 2 2 2 2 2 2 2 2 2 2 2 ORF 2579 2 2 2 2 2 2 2 2 2 2 2 ORF 2777 2 2 2 2 2 2 2 2 2 2 2 ORF 2819 2 2 2 2 2 2 2 2 2 2 2 ORF 2847 0 0 0 0 2 2 2 0 2 2 2 ORF 2858 2 2 2 2 2 2 2 2 2 2 2 ORF 3103 2 2 2 0 0 0 0 2 0 0 0 ORF 3184 2 2 2 2 2 2 2 2 2 2 2 ORF 3401 2 2 0 2 2 2 2 2 2 2 2 ORF 3792 2 2 2 2 2 2 2 2 2 2 2 ORF 3840 2 2 2 2 2 2 2 2 2 2 2 ORF 4101 2 2 2 2 2 2 2 2 2 2 2 ORF 660 0 0 0 2 2 2 2 2 2 2 2 ORF 757 0 0 0 2 2 2 2 2 2 2 2 ORF 799 0 0 0 0 2 2 2 2 2 2 2 ORF 817 2 2 2 2 0 0 0 2 0 0 0 CLIP42639- CLIP42652- CLIP80459- Gene CLIP8715-4b 4b Epi 4b Epi 4b Epi CLIP87889-4b CLIP87896-4b CLIP87911-4b CLIP87915-4b CLIP87917-4b CLIP74910-4b CLIP60383-4b Lmo0017 2 2 2 2 2 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 2 2 2 2 2 Lmo0066 0 0 2 0 0 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 0 0 0 0 0 Lmo0068 2 2 2 0 0 0 2 2 2 0 0 Lmo0069 2 2 2 0 0 0 2 2 2 0 0 Lmo0071 2 2 2 0 0 0 2 2 2 0 0 Lmo0072 2 2 2 2 2 2 2 2 2 2 2 Lmo0079 2 2 2 0 0 2 0 2 2 2 0 Lmo0080 2 2 2 0 0 2 2 2 2 2 0 Lmo0081 0 0 0 0 0 0 0 0 0 0 0 Lmo0082 2 2 2 2 2 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 0 2 2 2 2 2 Lmo0141 2 2 2 2 2 2 2 2 2 2 0 Lmo0143 0 0 0 0 2 0 0 0 0 0 0 Lmo0144 2 2 2 2 2 2 2 2 2 2 0 Lmo0147 2 2 2 0 0 0 2 2 2 2 2 Lmo0151 0 0 0 0 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 0 0 0 0 0 Lmo0304 0 0 0 0 0 2 0 0 0 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 0 0 Lmo0320 2 2 2 2 2 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 2 2 2 2 2 Lmo0338 0 0 0 0 0 0 0 0 0 0 0 Lmo0378 0 0 0 2 2 0 0 0 0 0 2 Lmo0379 0 0 0 0 0 0 0 0 0 0 0 Lmo0380 0 0 0 2 2 0 0 0 0 0 2 Lmo0381 0 0 0 2 2 0 0 0 0 0 2 Lmo0409 0 2 2 0 0 2 2 2 2 2 2 Lmo0419 2 2 2 2 2 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 2 2 2 2 2 Lmo0444 0 0 0 0 0 0 0 0 0 0 0 Lmo0448 0 2 2 2 0 2 0 0 0 0 2 Lmo0459 2 2 2 2 2 2 2 2 2 2 2 Lmo0462 2 2 2 2 2 2 2 2 2 2 2 Lmo0466 0 0 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 0 0 Lmo0472 0 0 0 0 0 0 0 0 2 0 0 Lmo0473 0 2 2 2 2 0 2 2 2 0 2 Lmo0474 2 2 2 2 2 2 2 2 2 2 2 Lmo0493 2 2 2 2 2 2 2 2 2 2 2 Lmo0497 0 0 0 0 0 0 0 0 0 0 0 Lmo0525 0 0 0 0 0 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 2 2 2 2 2 Lmo0630 2 2 2 0 0 2 2 2 2 2 0 Lmo0631 2 2 2 0 0 2 2 2 2 2 0 Lmo0632 2 2 2 0 0 2 2 2 2 2 0 Lmo0732 0 2 2 2 0 0 0 2 2 0 2 Lmo0733 2 2 2 2 2 2 2 2 2 2 2 Lmo0734 0 0 0 0 0 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 0 0 0 0 Lmo0750 0 0 0 0 0 0 0 0 0 0 0 Lmo0751 2 2 2 0 0 0 2 2 2 2 0 Lmo0752 2 2 2 2 2 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 2 2 2 2 2 Lmo0780 0 0 0 0 0 0 0 0 0 0 0 Lmo0801 0 2 2 0 0 0 0 0 0 0 0 Lmo0804 0 0 0 0 0 2 2 2 0 2 0 Lmo0832 2 2 2 2 2 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 2 2 2 2 2 Lmo0842 0 2 2 0 0 0 0 0 0 0 2 Lmo1030 2 2 2 2 2 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 2 2 2 2 2 Lmo1060 0 0 0 0 0 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 0 0 0 0 0 Lmo1076 0 0 0 0 0 0 0 0 0 0 0 Lmo1077 0 0 0 0 0 0 0 0 0 0 0 Lmo1080 0 0 0 0 0 0 0 0 0 0 0 Lmo1081 0 0 0 0 0 0 0 0 0 0 0 Lmo1082 0 0 0 0 0 0 0 0 0 0 0 Lmo1085 0 0 0 0 0 0 0 0 0 0 0 Lmo1088 0 0 0 0 0 0 0 0 0 0 0 Lmo1090 0 0 0 0 0 0 0 0 0 0 0 Lmo1091 0 0 0 0 0 0 0 0 0 0 0 Lmo1102 2 2 2 2 0 0 0 2 2 0 2 Lmo1115 0 0 0 0 0 0 0 0 0 0 0 Lmo1116 2 2 2 2 2 2 2 2 2 0 2 Lmo1118 0 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 0 Lmo1120 2 2 2 0 0 2 2 2 2 2 0 Lmo1133 2 2 2 2 2 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 2 2 2 2 2 Lmo1307 0 0 0 0 0 0 0 0 0 0 0 Lmo1441 2 2 2 2 2 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 2 2 2 2 2 Lmo1597 0 0 0 2 2 2 0 0 0 0 2 Lmo1604 2 2 2 2 0 0 0 0 0 0 0 Lmo1648 0 0 0 0 0 0 0 0 0 0 0 Lmo1666 2 2 2 2 2 2 2 2 2 2 2 Lmo1714 2 2 2 2 2 2 2 2 2 2 2 Lmo1968 0 0 0 0 0 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 0 0 0 0 Lmo2027 0 2 2 2 2 0 0 2 0 0 2 Lmo2276 2 2 2 2 0 0 0 0 0 0 2 Lmo2277 0 2 0 0 0 0 0 0 0 0 0 Lmo2311 0 0 0 0 0 0 0 0 0 0 0 Lmo2312 0 0 0 0 0 2 2 2 0 0 0 Lmo2324 2 0 0 0 0 2 2 2 0 0 0 Lmo2408 0 0 0 0 0 0 0 0 0 0 0 Lmo2443 2 2 2 2 2 2 2 2 2 2 2 Lmo2576 0 0 0 0 0 0 0 0 0 0 0 Lmo2594 2 2 2 2 2 2 2 2 2 2 2 Lmo2595 2 2 2 2 2 2 2 2 2 2 2 Lmo2671 2 2 2 2 2 2 2 2 2 2 2 Lmo2686 0 0 0 0 0 0 0 0 0 0 0 Lmo2732 2 2 2 2 2 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 2 2 2 2 2 Lmo2786 0 0 0 0 0 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 0 0 0 0 0 Lmo2807 0 2 2 0 0 0 2 2 2 0 0 Lmo2809 0 0 0 2 2 2 0 0 0 2 2 Lmo2821 2 2 2 2 2 2 2 2 2 2 2 Lin0060 0 0 0 0 0 0 0 0 0 2 0 Lin0197 0 0 0 0 0 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 0 Lin0415 2 2 2 2 2 2 2 0 0 0 2 Lin0453 2 2 2 2 2 2 2 2 2 2 2 Lin0454 2 2 2 2 2 2 2 2 2 2 2 Lin0455 0 2 2 2 0 2 2 2 2 2 0 Lin0465 0 0 0 0 0 0 0 0 0 0 0 Lin0476 0 2 2 0 0 0 0 0 0 0 0 Lin0661 0 2 0 0 0 0 0 0 0 0 0 Lin0665 2 2 2 2 2 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 0 Lin0740 0 2 2 0 0 0 0 0 0 0 0 Lin0803 0 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 0 0 2 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 0 Lin1073 2 2 2 2 2 2 2 2 2 2 2 Lin1083 0 0 0 0 0 0 0 0 0 0 0 Lin1084 2 2 0 0 2 2 2 2 2 2 0 Lin1090 2 2 2 2 2 2 2 2 2 2 2 Lin1204 2 2 2 2 2 2 2 2 2 2 2 Lin1262 2 2 2 2 0 0 0 0 0 0 2 Lin1299 2 2 2 2 2 0 2 2 2 0 2 Lin1328 2 2 2 2 0 0 0 0 0 0 2 Lin1452 0 0 0 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 0 0 0 0 0 Lin2397 0 0 0 0 0 2 0 0 0 0 0 Lin2494 0 2 0 2 2 2 0 0 0 0 2 Lin2603 0 0 0 0 0 2 2 0 0 0 0 Lin2724 0 0 0 0 0 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 0 0 0 0 0 Lin2743 0 0 0 0 0 0 0 0 0 0 0 Lin2744 0 0 0 2 0 0 0 0 0 0 0 Lin2839 0 0 0 0 0 0 0 0 0 0 0 Lin2918 0 0 0 0 0 0 0 0 0 0 0 ORF 105 2 2 2 2 2 0 2 2 2 0 2 ORF 1390 2 2 2 2 2 0 0 0 2 0 2 ORF 1445 2 2 2 2 2 2 2 2 2 2 2 ORF 1490 2 2 2 2 2 2 2 2 2 2 2 ORF 1491 2 2 2 2 2 2 2 2 2 2 2 ORF 1590 2 2 2 2 2 2 2 2 2 2 2 ORF 1761 2 2 2 2 2 2 2 2 2 2 2 ORF 2017 2 2 2 2 2 2 2 2 2 2 2 ORF 2074 2 2 2 2 2 2 2 2 2 2 2 ORF 2076 2 2 2 2 2 2 2 2 2 2 2 ORF 2110 2 2 2 2 2 2 2 2 2 2 2 ORF 2372 2 2 2 2 2 2 2 2 2 2 2 ORF 2541 2 2 2 2 2 2 2 2 2 2 2 ORF 2579 2 2 2 2 2 2 2 2 2 2 2 ORF 2777 2 2 2 2 2 2 2 2 2 2 2 ORF 2819 2 2 2 2 2 2 2 2 2 2 2 ORF 2847 2 2 2 2 2 0 2 2 2 0 2 ORF 2858 2 2 2 2 2 2 2 2 2 2 2 ORF 3103 0 0 0 2 2 2 0 0 0 2 2 ORF 3184 2 2 2 2 2 2 2 2 2 2 2 ORF 3401 2 2 2 2 2 2 2 2 2 2 2 ORF 3792 2 2 2 2 2 2 2 2 2 2 2 ORF 3840 2 2 2 2 2 2 2 2 2 2 2 ORF 4101 2 2 2 2 2 2 2 2 2 2 2 ORF 660 2 2 2 2 2 2 2 2 2 2 2 ORF 757 2 2 2 2 2 2 2 2 2 2 2 ORF 799 2 2 2 2 2 2 2 2 2 2 2 ORF 817 0 0 0 2 2 2 0 0 0 2 2 Gene CLIP72783-4b CLIP22573-4b Epi CLIP73722-4b CLIP87691-4b CLIP79619-4d CLIP 74912-4d Lmo0017 2 2 2 2 2 2 Lmo0036 2 2 2 2 2 2 Lmo0037 2 2 2 2 2 2 Lmo0066 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 Lmo0068 2 2 0 0 0 0 Lmo0069 2 2 0 0 0 0 Lmo0071 2 2 0 0 0 0 Lmo0072 2 2 2 2 2 2 Lmo0079 2 2 2 2 0 2 Lmo0080 2 2 2 2 0 2 Lmo0081 0 0 0 0 0 0 Lmo0082 2 2 2 2 2 2 Lmo0083 2 2 2 2 2 2 Lmo0094 2 2 2 2 2 2 Lmo0106 2 2 2 2 2 2 Lmo0141 2 2 2 2 2 2 Lmo0143 0 0 0 0 2 0 Lmo0144 2 2 2 2 2 2 Lmo0147 2 2 0 2 2 2 Lmo0151 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 Lmo0304 0 0 2 0 0 0 Lmo0310 0 0 2 0 0 0 Lmo0320 2 2 2 2 2 2 Lmo0333 2 2 2 2 2 2 Lmo0334 2 2 2 2 2 2 Lmo0338 0 0 0 0 0 0 Lmo0378 0 0 2 0 2 0 Lmo0379 0 0 0 0 0 0 Lmo0380 0 0 2 0 2 0 Lmo0381 0 0 2 0 2 0 Lmo0409 2 2 2 2 2 2 Lmo0419 2 2 2 2 2 2 Lmo0440 2 2 2 2 2 2 Lmo0444 0 0 0 0 0 0 Lmo0448 2 2 2 2 2 0 Lmo0459 2 2 2 2 2 2 Lmo0462 2 2 2 2 2 2 Lmo0466 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 Lmo0472 0 0 0 0 0 0 Lmo0473 2 2 2 0 2 0 Lmo0474 2 2 2 2 2 2 Lmo0493 2 2 2 2 2 2 Lmo0497 0 0 0 0 0 0 Lmo0525 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 Lmo0630 2 2 0 2 0 2 Lmo0631 2 2 0 2 0 2 Lmo0632 2 2 0 2 0 2 Lmo0732 2 2 2 2 2 0 Lmo0733 2 2 2 2 2 2 Lmo0734 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 Lmo0750 0 0 0 0 0 0 Lmo0751 2 2 2 2 0 2 Lmo0752 2 2 2 2 2 2 Lmo0753 2 2 2 2 2 2 Lmo0780 0 0 0 0 0 0 Lmo0801 2 2 0 0 0 0 Lmo0804 0 0 0 0 2 2 Lmo0832 2 2 2 2 2 2 Lmo0833 2 2 2 2 2 2 Lmo0834 2 2 2 2 2 2 Lmo0835 2 2 2 2 2 2 Lmo0842 2 2 2 2 2 0 Lmo1030 2 2 2 2 2 2 Lmo1036 2 2 2 2 2 2 Lmo1060 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 Lmo1076 0 0 0 0 0 0 Lmo1077 0 0 0 0 0 0 Lmo1080 0 0 0 0 0 0 Lmo1081 0 0 0 0 0 0 Lmo1082 0 0 0 0 0 0 Lmo1085 0 0 0 0 0 0 Lmo1088 0 0 0 0 0 0 Lmo1090 0 0 0 0 0 0 Lmo1091 0 0 0 0 0 0 Lmo1102 2 2 2 2 2 0 Lmo1115 0 0 0 0 0 0 Lmo1116 2 2 2 0 2 0 Lmo1118 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 Lmo1120 2 2 2 2 0 2 Lmo1133 2 2 2 2 2 2 Lmo1135 2 2 2 2 2 2 Lmo1307 0 0 0 0 0 0 Lmo1441 2 2 2 2 2 2 Lmo1451 2 2 2 2 2 2 Lmo1597 0 0 0 0 2 0 Lmo1604 2 2 2 2 2 0 Lmo1648 0 0 0 0 0 0 Lmo1666 2 2 2 2 2 2 Lmo1714 2 2 2 2 2 2 Lmo1968 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 Lmo2027 2 2 2 2 2 0 Lmo2276 2 2 2 2 2 0 Lmo2277 0 0 0 0 0 0 Lmo2311 0 0 0 0 0 0 Lmo2312 2 0 0 2 0 0 Lmo2324 2 0 0 2 0 0 Lmo2408 0 0 0 0 0 0 Lmo2443 2 2 2 2 2 2 Lmo2576 0 0 0 0 0 0 Lmo2594 2 2 2 2 2 2 Lmo2595 2 2 2 2 2 2 Lmo2671 2 2 2 2 2 2 Lmo2686 0 0 0 0 0 0 Lmo2732 2 2 2 2 2 2 Lmo2736 2 2 2 2 2 2 Lmo2786 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 Lmo2807 2 2 0 0 0 0 Lmo2809 0 2 2 2 2 2 Lmo2821 2 2 2 2 2 2 Lin0060 0 0 2 2 0 2 Lin0197 0 0 0 0 0 0 Lin0332 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 Lin0415 2 2 2 2 2 0 Lin0453 2 2 2 2 2 2 Lin0454 2 2 2 2 2 2 Lin0455 0 2 0 2 2 0 Lin0465 0 0 0 0 0 0 Lin0476 2 0 2 2 0 0 Lin0661 0 0 0 0 0 0 Lin0665 2 2 2 2 2 2 Lin0677 0 0 0 0 0 0 Lin0739 0 0 0 0 0 0 Lin0740 2 0 0 0 0 0 Lin0803 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 Lin1066 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 Lin1073 2 2 2 2 2 2 Lin1083 0 0 0 0 0 0 Lin1084 2 2 2 2 0 2 Lin1090 2 2 2 2 2 2 Lin1204 2 2 2 2 2 2 Lin1262 2 0 2 2 2 0 Lin1299 2 0 2 2 2 0 Lin1328 2 2 2 2 2 0 Lin1452 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 Lin2397 0 0 0 0 0 0 Lin2494 2 2 2 0 2 0 Lin2603 0 0 0 0 0 0 Lin2724 0 0 0 0 0 0 Lin2741 0 0 0 0 0 0 Lin2743 0 0 0 0 0 0 Lin2744 0 0 0 0 0 0 Lin2839 0 0 0 0 0 0 Lin2918 0 0 0 0 0 0 ORF 105 2 0 0 0 2 0 ORF 1390 0 0 0 2 2 0 ORF 1445 2 2 2 2 2 2 ORF 1490 2 2 2 2 2 2 ORF 1491 2 2 2 2 2 2 ORF 1590 2 2 2 2 2 2 ORF 1761 2 2 2 2 2 2 ORF 2017 2 2 2 2 2 2 ORF 2074 2 2 2 2 2 2 ORF 2076 2 2 2 2 2 2 ORF 2110 2 2 2 2 2 2 ORF 2372 2 2 2 2 2 2 ORF 2541 2 2 2 2 2 2 ORF 2579 2 2 2 2 2 2 ORF 2777 2 2 2 2 2 2 ORF 2819 2 2 2 2 2 2 ORF 2847 2 2 0 0 2 0 ORF 2858 2 2 2 2 2 2 ORF 3103 0 0 2 2 2 2 ORF 3184 2 2 2 2 2 0 ORF 3401 2 2 2 2 2 2 ORF 3792 2 2 2 2 2 2 ORF 3840 2 2 2 2 2 2 ORF 4101 2 2 2 2 2 2 ORF 660 2 2 2 2 2 2 ORF 757 2 2 2 2 2 2 ORF 799 2 2 2 2 2 2 ORF 817 0 0 0 2 2 2 Gene CLIP 74913-4e CLIP78003-4e CLIP79455-4e CLIP86309-4c CLIP81065-4c CLIP74911-4c CLIP78025b-4a CLIP74908-4a CLIP71988-4a CLIP6645-iva/lon-5 PAM55-5 Lmo0017 2 2 2 2 2 2 0 0 0 0 0 Lmo0036 2 2 2 2 0 0 0 0 0 2 2 Lmo0037 2 2 2 2 0 0 0 0 0 2 2 Lmo0066 0 2 0 0 2 2 2 0 0 2 0 Lmo0067 0 0 0 0 0 0 0 0 0 0 0 Lmo0068 2 0 2 0 0 0 0 0 0 0 0 Lmo0069 2 0 2 0 0 0 0 0 0 0 0 Lmo0071 2 0 2 0 0 0 0 0 0 0 0 Lmo0072 2 2 2 2 0 0 0 0 0 0 0 Lmo0079 2 2 2 2 2 2 0 0 0 2 0 Lmo0080 2 2 2 2 0 0 0 0 0 0 0 Lmo0081 0 0 0 0 0 0 0 0 0 0 0 Lmo0082 2 2 2 2 2 2 2 2 2 0 0 Lmo0083 2 2 2 2 2 2 2 2 2 0 0 Lmo0094 2 2 2 2 0 0 0 0 0 0 0 Lmo0106 2 2 2 2 2 2 2 2 2 2 0 Lmo0141 2 2 2 2 2 0 2 2 2 0 0 Lmo0143 0 0 0 0 0 0 2 2 2 0 0 Lmo0144 2 2 2 2 2 0 2 2 2 0 0 Lmo0147 2 2 2 2 2 2 0 2 2 2 2 Lmo0151 0 0 0 0 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 2 2 2 2 2 0 0 Lmo0253 0 0 0 0 2 2 2 2 2 0 0 Lmo0304 0 0 0 0 2 0 0 0 0 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 0 0 Lmo0320 2 2 2 2 0 0 2 0 0 0 0 Lmo0333 2 2 2 2 2 2 0 0 0 0 0 Lmo0334 2 2 2 2 2 2 0 0 0 0 0 Lmo0338 0 0 0 0 0 0 0 0 0 2 0 Lmo0378 0 0 0 0 0 0 0 0 0 0 0 Lmo0379 0 0 0 0 2 2 0 0 0 0 0 Lmo0380 0 0 0 0 2 2 0 0 0 0 0 Lmo0381 0 0 0 0 0 0 2 2 2 0 0 Lmo0409 2 2 2 2 0 0 0 0 0 0 0 Lmo0419 2 2 2 2 2 2 0 0 0 0 0 Lmo0440 2 2 2 2 2 2 2 2 2 0 0 Lmo0444 0 0 0 0 2 2 0 0 0 0 0 Lmo0448 0 0 2 2 2 2 0 0 2 0 0 Lmo0459 2 2 2 2 2 0 2 2 2 0 0 Lmo0462 2 2 2 2 2 0 2 2 2 0 0 Lmo0466 0 0 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 0 0 Lmo0472 0 0 0 0 2 2 0 0 0 0 0 Lmo0473 2 0 2 0 2 2 2 2 2 0 2 Lmo0474 2 2 2 2 0 0 0 0 0 0 0 Lmo0493 2 2 2 2 2 0 0 0 0 0 2 Lmo0497 0 0 0 0 0 0 0 0 0 0 0 Lmo0525 0 0 0 0 0 0 0 0 0 0 0 Lmo0549 2 2 2 2 2 2 0 0 0 0 0 Lmo0630 2 2 2 2 2 0 0 0 0 0 2 Lmo0631 2 2 2 2 2 0 0 0 0 0 0 Lmo0632 2 2 2 2 2 0 0 0 0 2 2 Lmo0732 0 2 2 2 2 2 2 2 2 2 2 Lmo0733 2 2 2 2 2 2 2 2 2 0 0 Lmo0734 0 0 0 0 0 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 0 0 0 0 Lmo0750 0 0 0 2 0 0 2 2 2 0 0 Lmo0751 2 2 2 2 0 0 2 2 2 0 2 Lmo0752 2 2 2 2 0 0 2 2 2 2 2 Lmo0753 2 2 2 2 0 0 2 2 2 2 2 Lmo0780 0 0 0 0 2 2 2 2 2 2 2 Lmo0801 0 0 2 0 0 0 0 0 2 0 0 Lmo0804 0 2 0 2 2 2 2 2 2 0 0 Lmo0832 2 2 2 2 0 0 0 0 0 0 0 Lmo0833 2 2 2 2

0 0 Lmo0834 2 2 2 2

0 0 0 0 0 Lmo0835 2 2 2 2 0 0 0 0 0 0 0 Lmo0842 0 0 2 2 0 0 0 0 2 0 0 Lmo1030 2 2 2 2 2 2 0 0 0 2 2 Lmo1036 2 2 2 2 2 2 0 0 0 2 2 Lmo1060 0 0 0 0 0 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 0 0 0 0 0 Lmo1076 0 0 0 0 0 0 0 0 0 0 0 Lmo1077 0 0 0 0 0 0 0 0 0 0 0 Lmo1080 0 0 0 0 0 0 0 0 0 0 0 Lmo1081 0 0 0 0 0 0 0 0 0 0 0 Lmo1082 0 0 0 0 0 0 0 0 0 0 0 Lmo1085 0 0 0 0 0 0 0 0 0 0 0 Lmo1088 0 0 0 0 0 0 0 0 0 0 0 Lmo1090 0 0 0 0 0

0 0 0 0 0 Lmo1091 0 0 0 0 0 0 0 0 0 0 0 Lmo1102 0 2 2 2 2 2 2 2 2 2 2 Lmo1115 0 2 0 0 2 2 2 0 0 0 0 Lmo1116 2 0 2 0 0 2 0 0 0 0 2 Lmo1118 0 0 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 0 0 Lmo1120 2 2 2 2 0 0 0 0 0 2 2 Lmo1133 2 2 2 2 2 2 2 2 2 0 0 Lmo1135 2 2 2 2 2 2 0 0 2 0 0 Lmo1307 0 0 0 0 2 2 2 2 2 0 2 Lmo1441 2 2 2 2 0 0 0 0 0 0 0 Lmo1451 2 2 2 2 0 0 0 0 0 0 0 Lmo1597 0 0 0 0 0 0 0 0 0 0 2 Lmo1604 2 0 2 2 2 2 0 0 2 0 2 Lmo1648 0 0 2 0 0 2 0 0 0 0 0 Lmo1666 2 2 2 2 0 0 0 0 0 0 0 Lmo1714 2 2 2 2 0 0 2 2 2 0 0 Lmo1968 0 0 0 0 0 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 0 0 0 0 Lmo2027 2 2 2 2 2 2 0 0 0 0 0 Lmo2276 0 2 2 2 0 0 0 0 0 0 0 Lmo2277 0 0 0 0 2 0 0 0 2 0 0 Lmo2311 0 0 0 0 2 0 2 2 2 0 0 Lmo2312 0 2 0 2 0 0 2 2 2 0 0 Lmo2324 0 2 0 2 0 0 0 2 2 0 0 Lmo2408 0 0 0 0 0 0 0 0 0 0 0 Lmo2443 2 2 2 2 0 0 2 2 2 0 0 Lmo2576 0 0 0 0 2 2 0 0 0 0 0 Lmo2594 2 2 2 2 2 2 0 0 2 0 0 Lmo2595 2 2 2 2 0 2 2 2 2 0 0 Lmo2671 2 2 2 2 0 0 0 0 0 2 0 Lmo2686 0 0 0 0 2 0 0 0 0 2 0 Lmo2732 2 2 2 2 2 2 2 2 2 0 0 Lmo2736 2 2 2 2 2 2 2 2 2 0 0 Lmo2786 0 0 0 0 2 2 0 0 0 0 0 Lmo2787 0 0 0 0 2 2 0 0 0 0 0 Lmo2807 2 0 2 0 0 0 0 2 2 0 0 Lmo2809 0 2 0 2 0 0 0 0 0 0 0 Lmo2821 2 2 2 2 2 2 0 0 0 0 0 Lin0060 0 2 0 2 0 0 0 0 0 0 0 Lin0197 0 0 0 0 0 0 0 0 0 2 2 Lin0332 0 0 0 0 0 0 0 0 0 0 0 Lin0397 0 0 0 0 0 0 0 0 0 0 0 Lin0415 0 2 2 2 2 2 0 0 0 0 0 Lin0453 2 2 2 2 0 0 0 0 0 0 0 Lin0454 2 2 2 2 2 2 2 2 2 2 0 Lin0455 2 0 2 2 2 0 2 2 2 2 0 Lin0465 0 0 0 0 0 0 0 0 0 0 0 Lin0476 0 0 0 0 2 2 0 0 0 0 0 Lin0661 0 0 0 0 2 0 0 0 0 0 0 Lin0665 2 2 2 2 2 2 2 2 2 0 0 Lin0677 0 0 0 0 2 2 2 2 2 0 0 Lin0739 0 0 0 0 0 0 0 0 0 0 0 Lin0740 0 2 0 2 2 2 2 0 2 0 0 Lin0803 0 0 0 0 0 0 0 0 0 0 0 Lin0868 0 0 0 0 0 0 0 0 0 0 0 Lin1066 0 0 0 2 0 0 0 0 0 0 0 Lin1069 0 0 0 0 0 0 0 0 0 0 0 Lin1073 2 2 2 2 2 2 2 2 2 2 2 Lin1083 0 0 0 0 0 0 0 0 0 0 0 Lin1084 2 2 2 2 0 0 0 0 0 2 0 Lin1090 2 2 2 2 2 2 2 0 2 0 2 Lin1204 2 2 2 2 0 0 2 2 2 0 0 Lin1262 0 2 2 2 2 2 2 0 2 0 0 Lin1299 0 2 2 2 2 2 2 0 2 0 0 Lin1328 0 2 2 2 2 2 2 0 2 2 2 Lin1452 0 0 0 0 0 0 0 0 0 0 0 Lin1621 0 0 0 0 0 0 2 2 2 0 0 Lin2397 0 2 0 2 0 0 0 0 0 0 0 Lin2494 0 0 0 0 2 2 2 2 2 0 0 Lin2603 0 0 0 0 0 0 2 2 2 0 0 Lin2724 0 0 0 0 2 0 2 2 2 2 0 Lin2741 0 0 0 0 0 0 0 0 0 0 0 Lin2743 0 0 0 0 2 0 0 0 0 0 0 Lin2744 0 0 0 2 2 2 0 0 0 0 0 Lin2839 0 0 0 0 0 0 0 0 0 0 0 Lin2918 0 0 0 0 0 0 0 0 0 0 0 ORF 105 2 0 2 0 0 0 0 0 0 0 2 ORF 1390 0 2 2 2 0 0 2 0 2 0 2 ORF 1445 2 2 2 2 2 2 2 2 2 0 2 ORF 1490 2 2 2 2 2 2 0 0 0 2 0 ORF 1491 2 2 2 2 2 2 0 0 0 2 0 ORF 1590 2 2 2 2 2 2 0 0 0 0 0 ORF 1761 2 2 2 2 0 0 0 0 0 0 0 ORF 2017 2 2 2 2 2 2 0 0 2 0 2 ORF 2074 2 2 2 2 0 0 2 2 2 2 2 ORF 2076 2 2 2 2 0 0 2 2 2 2 2 ORF 2110 2 2 2 2 0 0 0 0 0 2 2 ORF 2372 2 2 2 2 0 0 0 0 0 0 2 ORF 2541 2 2 2 2 0 0 0 0 0 0 0 ORF 2579 2 2 2 2 0 0 2 2 2 2 2 ORF 2777 2 2 2 2 0 0 0 0 0 0 2 ORF 2819 2 2 2 2 0 0 0 0 0 0 0 ORF 2847 2 0 2 0 0 0 2 2 2 0 0 ORF 2858 2 2 2 2 2 2 0 0 2 2 2 ORF 3103 0 2 0 2 0 0 0 0 0 0 0 ORF 3184 2 2 2 2 0 2 0 0 2 0 2 ORF 3401 2 2 2 2 0 0 0 0 2 2 2 ORF 3792 2 2 2 2 2 2 2 2 2 0 2 ORF 3840 2 2 2 2 0 0 0 0 0 0 0 ORF 4101 2 2 2 2 2 2 0 0 2 2 2 ORF 660 2 2 2 2 0 0 0 0 0 0 0 ORF 757 2 2 2 2 0 0 0 0 0 0 0 ORF 799 2 2 2 2 0 0 0 0 0 0 0 ORF 817 0 2 0 2 0 2 0 0 0 2 0 CLIP86784- CLIP12065b- CLIP88111b- CLIP CLIP87973- CLIP86579- Gene iva/lon-5 iva/lon-

iva/iva-5 74914-iva/iva-5 CLIP87073-wel-6a wel-4c sel-1/2b CLIP73021-sel-1/2b CLIP88307-inno-6b Lmo0017 0 0 0 0 0 0 0 0 0 Lmo0036 2 2 2 2 0 0 2 0 0 Lmo0037 2 2 2 2 0 0 2 0 0 Lmo0066 0 2 2 0 0 0 0 0 0 Lmo0067 0 0 0 0 0 0 0 0 0 Lmo0068 0 0 0 0 0 0 0 0 0 Lmo0069 0 0 0 0 0 0 0 0 0 Lmo0071 0 0 0 0 0 0 0 0 0 Lmo0072 0 0 0 0 0 0 0 0 0 Lmo0079 0 2 0 0 0 0 2 0 0 Lmo0080 0 0 0 0 0 0 2 0 0 Lmo0081 0 0 0 0 0 0 0 0 0 Lmo0082 0 0 0 0 0 0 0 0 0 Lmo0083 0 0 0 0 0 0 0 0 0 Lmo0094 0 0 0 0 0 0 0 0 0 Lmo0106 0 2 0 0 2 0 2 2 0 Lmo0141 0 0 0 0 0 0 0 0 0 Lmo0143 0 0 0 0 0 0 0 0 0 Lmo0144 0 0 0 0 0 0 0 0 0 Lmo0147 2 2 0 2 0 2 0 2 2 Lmo0151 0 0 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 2 2 0 2 0 Lmo0253 0 0 0 0 0 0 0 2 0 Lmo0304 0 0 0 0 0 2 0 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 Lmo0320 0 0 0 0 0 0 0 0 0 Lmo0333 0 0 0 0 0 0 0 0 0 Lmo0334 0 0 0 0 2 0 0 0 0 Lmo0338 0 2 0 0 0 0 0 0 0 Lmo0378 0 0 0 0 0 0 0 0 0 Lmo0379 0 0 0 0 0 0 0 0 0 Lmo0380 0 0 0 0 0 0 0 0 0 Lmo0381 0 0 0 0 0 0 0 0 0 Lmo0409 0 0 0 0 0 0 0 0 0 Lmo0419 0 0 0 0 2 2 0 0 0 Lmo0440 0 0 0 0 0 0 0 0 0 Lmo0444 0 0 0 0 2 2 0 0 0 Lmo0448 0 0 0 0 2 2 0 0 2 Lmo0459 0 0 0 0 0 0 0 0 0 Lmo0462 0 0 0 0 0 0 0 0 0 Lmo0466 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 Lmo0472 0 0 0 0 2 0 0 0 2 Lmo0473 2 0 2 2 2 0 0 0 0 Lmo0474 0 0 0 0 0 0 0 0 0 Lmo0493 2 0 2 2 0 2 2 0 0 Lmo0497 0 0 0 0 0 0 0 0 0 Lmo0525 0 0 0 0 2 0 0 0 0 Lmo0549 0 0 0 0 0 0 0 0 0 Lmo0630 2 0 0 2 2 2 0 0 0 Lmo0631 0 0 0 0 2 2 0 0 0 Lmo0632 2 2 2 2 2 2 0 0 0 Lmo0732 2 0 0 0 0 2 0 0 2 Lmo0733 0 0 0 0 0 0 0 0 0 Lmo0734 0 0 0 0 2 2 0 0 0 Lmo0735 0 0 0 2 2 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 0 0 Lmo0750 0 0 0 0 0 0 0 0 0 Lmo0751 0 0 0 0 0 0 0 0 0 Lmo0752 2 2 2 2 0 0 0 0 0 Lmo0753 2 2 2 2 0 0 0 0 0 Lmo0780 0 0 0 0 0 2 0 0 0 Lmo0801 0 0 0 0 0 2 0 2 2 Lmo0804 0 0 0 0 0 0 0 0 0 Lmo0832 0 0 0 0 0 0 0 0 0 Lmo0833 0 0 0 0 0 0 0 0 0 Lmo0834 0 0 0 0 0 0 0 0 0 Lmo0835 0 0 0 0 0 0 0 0 0 Lmo0842 0 0 0 2 2 2 0 0 2 Lmo1030 2 2 2 2 0 0 0 0 0 Lmo1036 2 2 2 2 0 0 0 0 0 Lmo1060 0 0 0 0 2 2 0 0 0 Lmo1061 0 0 0 0 2 0 0 0 0 Lmo1063 0 0 0 0 2 2 0 0 0 Lmo1076 0 0 0 0 0 0 2 2 0 Lmo1077 0 0 0 0 0 0 2 2 0 Lmo1080 0 0 0 0 0 0 0 2 0 Lmo1081 0 0 0 0 0 0 2 2 0 Lmo1082 0 0 0 0 0 0 2 2 0 Lmo1085 0 0 0 0 0 0 0 0 0 Lmo1088 0 0 0 0 0 0 0 2 0 Lmo1090 0 0 0 0 0 0 2 2 0 Lmo1091 0 0 0 0 0 0 2 2 0 Lmo1102 2 2 2 2 0 0 2 0 0 Lmo1115 0 2 2 0 0 0 2 0 0 Lmo1116 2 0 2 2 0 0 0 0 0 Lmo1118 0 0 0 2 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 Lmo1120 2 0 0 2 2 0 0 2 2 Lmo1133 0 0 0 0 0 0 0 0 0 Lmo1135 0 0 0 0 0 0 0 0 0 Lmo1307 2 0 0 0 2 0 0 0 0 Lmo1441 0 0 0 0 0 0 0 0 0 Lmo1451 0 0 0 0 0 0 0 0 0 Lmo1597 2 0 2 2 2 2 0 0 0 Lmo1604 0 0 0 2 0 0 0 0 2 Lmo1648 2 0 0 0 0 2 0 0 0 Lmo1666 0 0 0 0 0 0 0 2 0 Lmo1714 0 0 0 0 0 0 0 0 0 Lmo1968 0 0 0 0 0 0 0 0 0 Lmo1973 0 0 0 0 0 0 0 0 0 Lmo1974 0 0 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 0 0 Lmo2027 0 0 0 0 0 0 0 0 0 Lmo2276 0 0 0 0 0 0 0 0 0 Lmo2277 0 0 0 2 0 0 0 0 2 Lmo2311 0 0 0 0 0 0 0 0 0 Lmo2312 0 0 0 0 0 2 0 0 0 Lmo2324 0 0 0 0 0 2 0 0 0 Lmo2408 0 0 0 0 2 2 0 0 0 Lmo2443 0 0 0 0 0 0 0 0 0 Lmo2576 0 0 0 0 0 0 0 0 0 Lmo2594 0 0 0 0 0 0 0 0 2 Lmo2595 0 0 0 0 0 0 0 0 0 Lmo2671 0 0 0 0 2 2 0 2 0 Lmo2686 0 0 0 0 0 0 0 0 0 Lmo2732 0 0 0 0 0 0 0 0 0 Lmo2736 0 0 0 0 0 0 0 0 0 Lmo2786 0 0 0 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 0 0 0 Lmo2807 0 0 0 2 0 0 0 2 2 Lmo2809 0 0 0 0 0 0 0 2 0 Lmo2821 0 0 0 0 0 0 0 0 0 Lin0060 0 0 0 0 0 0 0 0 2 Lin0197 2 2 2 2 2 2 2 2 2 Lin0332 0 0 0 0 0 0 0 0 2 Lin0397 0 0 0 0 0 0 0 0 2 Lin0415 0 0 0 0 2 2 0 2 2 Lin0453 0 0 0 0 2 2 0 0 2 Lin0454 0 0 0 0 2 2 0 0 2 Lin0455 0 2 0 0 0 2 0 0 2 Lin0465 0 0 0 0 0 0 0 0 2 Lin0476 0 0 0 0 0 0 0 0 2 Lin0661 0 0 0 0 0 0 0 0 2 Lin0665 0 0 0 0 0 2 2 2 2 Lin0677 0 0 0 0 0 0 0 0 2 Lin0739 0 0 0 0 0 0 0 0 2 Lin0740 0 0 0 0 0 0 0 0 2 Lin0803 0 0 0 0 0 0 0 0 2 Lin0868 0 0 0 0 0 0 0 0 2 Lin1066 0 0 0 0 0 0 0 0 2 Lin1069 0 0 0 0 0 0 0 0 2 Lin1073 2 2 0 2 2 0 0 0 2 Lin1083 0 0 0 0 0 0 0 0 2 Lin1084 0 0 0 0 2 0 2 2 2 Lin1090 2 0 2 2 0 0 0 0 2 Lin1204 0 0 0 0 0 0 0 0 2 Lin1262 0 0 0 0 0 0 0 0 2 Lin1299 0 0 2 2 0 0 2 0 2 Lin1328 2 2 2 0 0 0 2 0 2 Lin1452 0 0 0 0 0 0 0 0 2 Lin1621 0 0 0 0 0 0 0 0 2 Lin2397 0 0 0 0 0 2 2 0 2 Lin2494 0 0 0 0 2 2 2 0 2 Lin2603 0 0 0 0 0 0 2 0 2 Lin2724 0 0 0 0 0 0 0 0 2 Lin2741 0 0 0 0 0 0 0 0 2 Lin2743 0 2 0 0 2 0 2 0 2 Lin2744 0 2 0 0 2 0 2 0 2 Lin2839 0 0 0 0 0 0 0 0 2 Lin2918 0 0 0 0 0 0 0 0 2 ORF 105 2 0 2 2 0 0 0 0 0 ORF 1390 0 0 0 2 0 0 2 0 0 ORF 1445 2 0 0 2 0 0 0 0 0 ORF 1490 0 2 0 0 2 2 2 2 0 ORF 1491 0 2 0 0 2 2 2 2 0 ORF 1590 0 0 0 0 0 0 0 0 0 ORF 1761 0 0 0 0 0 0 0 0 0 ORF 2017 2 0 0 2 0 0 0 0 0 ORF 2074 2 2 2 2 2 2 2 0 0 ORF 2076 2 2 2 2 2 2 2 0 0 ORF 2110 2 0 0 2 0 2 0 0 0 ORF 2372 0 0 0 2 2 2 0 0 0 ORF 2541 0 0 0 0 0 0 0 0 0 ORF 2579 2 2 2 2 2 2 2 0 0 ORF 2777 2 0 0 2 0 2 2 2 0 ORF 2819 0 0 0 0 0 0 0 0 0 ORF 2847 0 0 0 0 0 0 0 0 0 ORF 2858 2 0 0 0 0 2 0 2 2 ORF 3103 0 0 0 0 0 0 0 0 0 ORF 3184 0 0 0 2 0 2 0 0 0 ORF 3401 0 0 0 0 0 0 0 0 0 ORF 3792 0 0 0 0 0 0 0 0 0 ORF 3840 0 0 0 2 0 0 0 0 0 ORF 4101 2 0 0 2 2 2 0 0 2 ORF 660 0 0 0 0 0 0 0 0 0 ORF 757 0 0 0 0 0 0 0 0 0 ORF 799 0 0 0 0 2 0 0 0 0 ORF 817 0 2 0 0 0 0 0 0 0 Gene CLIP86490-inno CLIP88566-inno-6a CLIP11262-inno-6a CLIP 74915-inno-6a CLIP 74916-inno-6b CLIP71989-inno-6b CLIP71990-inno-6b CLIP73019-gravi CLIP12515-murrayi Lmo0017 0 0 0 0 0 0 0 0 0 Lmo0036 0 0 0 0 0 0 0 2 2 Lmo0037 0 0 0 0 0 0 0 0 0 Lmo0066 0 0 0 0 0 2 2 0 0 Lmo0067 0 0 0 0 0 2 2 0 0 Lmo0068 0 0 0 0 0 2 2 0 0 Lmo0069 0 0 0 0 0 0 0 0 0 Lmo0071 0 0 0 0 0 0 0 0 0 Lmo0072 2 0 0 0 2 0 0 0 0 Lmo0079 0 0 0 0 0 0 0 0 0 Lmo0080 0 0 0 0 0 0 0 0 0 Lmo0081 0 0 0 0 0 0 0 0 0 Lmo0082 0 0 0 0 0 0 0 0 0 Lmo0083 0 0 0 0 0 0 0 0 0 Lmo0094 0 0 0 0 0 0 0 0 0 Lmo0106 0 0 0 0 0 0 0 0 0 Lmo0141 0 0 0 0 0 0 0 0 0 Lmo0143 0 0 0 0 0 0 0 0 0 Lmo0144 0 0 0 0 0 0 0 0 0 Lmo0147 2 2 0 0 0 2 2 0 0 Lmo0151 0 0 0 0 0 0 0 0 0 Lmo0171 0 0 0 0 0 0 0 0 0 Lmo0172 0 0 0 0 0 0 0 0 0 Lmo0252 0 0 0 0 0 0 0 0 0 Lmo0253 0 0 0 0 0 0 0 0 0 Lmo0304 2 2 0 0 0 2 2 0 0 Lmo0310 0 0 0 0 0 0 0 0 0 Lmo0320 0 0 0 0 0 0 2 0 0 Lmo0333 0 0 0 0 0 0 0 0 0 Lmo0334 0 0 0 0 0 0 0 0 0 Lmo0338 0 2 0 0 0 0 0 0 2 Lmo0378 2 0 0 0 2 2 2 0 0 Lmo0379 2 0 0 0 2 0 0 0 0 Lmo0380 2 0 0 0 2 0 0 0 0 Lmo0381 2 0 0 0 2 0 0 0 0 Lmo0409 0 0 0 0 0 0 0 0 0 Lmo0419 0 0 0 0 0 0 0 0 0 Lmo0440 0 0 0 0 0 0 0 0 0 Lmo0444 0 0 0 0 0 0 0 0 0 Lmo0448 2 2 0 0 0 2 2 0 0 Lmo0459 0 0 0 0 0 0 0 0 0 Lmo0462 0 0 0 0 0 0 0 0 0 Lmo0466 0 0 0 0 0 0 0 0 0 Lmo0467 0 0 0 0 0 0 0 0 0 Lmo0471 0 0 0 0 0 0 0 0 0 Lmo0472 2 2 0 2 2 2 2 0 0 Lmo0473 0 2 0 0 0 2 2 0 0 Lmo0474 0 0 0 0 0 2 2 0 0 Lmo0493 0 0 0 0 0 0 0 0 0 Lmo0497 0 0 0 0 0 0 0 0 0 Lmo0525 0 0 0 0 0 0 0 0 0 Lmo0549 0 0 0 0 0 0 0 0 0 Lmo0630 0 0 0 0 0 0 0 0 0 Lmo0631 0 0 0 0 0 0 0 0 0 Lmo0632 0 0 0 0 0 0 0 0 0 Lmo0732 2 2 2 0 0 2 2 0 0 Lmo0733 0 0 0 0 0 0 0 0 0 Lmo0734 0 0 0 0 0 0 0 0 0 Lmo0735 0 0 0 0 0 0 0 0 0 Lmo0739 0 0 0 0 0 0 0 0 0 Lmo0750 0 0 0 0 0 0 0 0 0 Lmo0751 0 0 0 0 0 0 0 0 0 Lmo0752 0 0 0 0 0 0 0 0 0 Lmo0753 0 0 0 0 0 0 0 0 0 Lmo0780 0 0 0 0 0 0 0 0 0 Lmo0801 0 0 0 0 0 0 0 0 0 Lmo0804 0 0 0 0 0 0 0 0 0 Lmo0832 0 0 0 0 0 0 0 0 0 Lmo0833 0 0 0 0 0 0 0 0 0 Lmo0834 0 0 0 0 0 0 0 0 0 Lmo0835 0 0 0 0 0 0 0 0 0 Lmo0842 2 2 0 0 2 2 2 0 0 Lmo1030 0 0 0 0 0 0 0 0 0 Lmo1036 0 0 0 0 0 0 0 0 0 Lmo1060 0 0 0 0 0 0 0 0 0 Lmo1061 0 0 0 0 0 0 0 0 0 Lmo1063 0 0 0 0 0 0 0 0 0 Lmo1076 0 0 0 0 0 0 0 0 0 Lmo1077 0 0 0 0 0 0 0 2 2 Lmo1080 0 0 0 0 0 0 0 0 0 Lmo1081 0 0 0 0 0 0 0 0 0 Lmo1082 0 0 0 0 0 0 0 0 0 Lmo1085 0 0 0 0 0 0 0 0 0 Lmo1088 0 0 0 0 0 0 0 0 0 Lmo1090 0 0 0 0 0 0 0 0 0 Lmo1091 0 0 0 0 0 0 0 0 0 Lmo1102 0 0 0 0 0 0 2 0 0 Lmo1115 0 0 0 0 0 0 2 0 0 Lmo1116 2 2 0 0 2 2 2 0 0 Lmo1118 0 0 0 0 0 0 0 0 0 Lmo1119 0 0 0 0 0 0 0 0 0 Lmo1120 0 0 2 0 0 0 0 0 0 Lmo1133 0 0 0 0 0 0 0 0 0 Lmo1135 0 0 0 0 0 0 0 0 0 Lmo1307 0 0 0 0 0 0 0 0 0 Lmo1441 0 0 0 0 0 0 0 0 0 Lmo1451 0 0 0 0 0 0 0 0 0 Lmo1597 0 0 0 0 0 0 0 0 0 Lmo1604 2 2 2 0 0 2 2 0 0 Lmo1648 2 0 0 0 0 0 2 0 0 Lmo1666 0 0 0 0 0 0 0 0 0 Lmo1714 0 0 0 0 0 2 2 0 0 Lmo1968 0 2 0 0 0 0 0 0 0 Lmo1973 0 2 0 0 0 0 0 0 0 Lmo1974 0 2 0 0 0 0 0 0 0 Lmo2026 0 0 0 0 0 0 0 0 0 Lmo2027 0 0 0 0 0 0 0 0 0 Lmo2276 0 0 0 0 0 0 0 0 0 Lmo2277 2 0 0 0 0 0 0 0 0 Lmo2311 0 0 0 0 0 0 0 0 0 Lmo2312 2 0 0 0 0 2 0 0 0 Lmo2324 2 2 0 0 2 0 0 0 0 Lmo2408 0 0 0 0 0 0 0 0 0 Lmo2443 0 0 0 0 0 0 0 0 0 Lmo2576 0 0 0 0 0 0 0 0 0 Lmo2594 2 2 0 0 0 2 0 0 0 Lmo2595 0 0 0 0 0 0 0 0 0 Lmo2671 0 0 0 0 0 0 0 0 0 Lmo2686 0 0 0 0 0 0 0 0 0 Lmo2732 0 0 0 0 0 0 0 0 0 Lmo2736 0 0 0 0 0 0 0 0 0 Lmo2786 0 0 0 0 0 0 0 0 0 Lmo2787 0 0 0 0 0 0 0 0 0 Lmo2807 0 0 0 0 0 0 0 0 0 Lmo2809 0 0 0 0 0 2 2 0 0 Lmo2821 0 0 0 0 0 0 0 0 0 Lin0060 0 0 2 2 0 2 2 0 0 Lin0197 2 2 2 2 2 2 2 0 0 Lin0332 0 0 2 2 0 0 0 0 0 Lin0397 0 2 2 2 0 0 0 0 0 Lin0415 2 2 2 2 2 2 2 0 0 Lin0453 2 2 2 2 2 2 2 0 0 Lin0454 2 2 2 2 2 2 2 0 0 Lin0455 2 2 2 2 2 2 2 0 0 Lin0465 2 2 2 2 2 2 2 0 0 Lin0476 0 2 2 0 0 0 0 0 0 Lin0661 2 2 2 2 2 2 2 0 0 Lin0665 2 2 2 2 2 2 2 0 0 Lin0677 2 2 2 2 2 2 2 0 0 Lin0739 2 2 2 2 2 2 2 0 0 Lin0740 2 2 2 2 2 2 2 0 0 Lin0803 2 2 2 2 2 2 2 0 0 Lin0868 0 2 2 2 0 0 0 0 0 Lin1066 0 2 2 2 0 0 0 0 0 Lin1069 0 2 2 2 2 0 0 0 0 Lin1073 2 2 2 2 2 2 2 0 0 Lin1083 0 0 2 2 0 0 0 0 0 Lin1084 2 2 2 2 0 2 2 0 0 Lin1090 0 2 2 2 0 2 2 0 0 Lin1204 0 0 2 2 0 2 2 0 0 Lin1262 2 2 2 0 0 2 2 0 0 Lin1299 2 2 2 2 2 2 2 0 0 Lin1328 2 2 2 2 2 2 2 0 0 Lin1452 2 2 2 2 2 2 2 0 0 Lin1621 2 0 2 2 2 2 2 0 0 Lin2397 2 2 2 0 0 2 2 0 0 Lin2494 2 2 2 2 2 2 2 0 0 Lin2603 0 0 2 0 2 2 2 0 0 Lin2724 2 2 2 2 2 2 2 0 0 Lin2741 2 2 2 2 2 2 2 0 0 Lin2743 2 0 2 2 2 2 2 0 0 Lin2744 2 2 2 2 2 2 2 0 0 Lin2839 2 2 2 2 2 2 2 0 0 Lin2918 2 2 2 2 2 2 2 0 0 ORF 105 0 0 0 0 0 2 2 0 0 ORF 1390 2 0 0 0 0 0 2 0 0 ORF 1445 0 0 0 0 0 0 0 0 0 ORF 1490 0 0 0 0 0 0 0 0 0 ORF 1491 0 0 0 0 0 0 0 0 0 ORF 1590 0 0 0 0 0 0 0 0 0 ORF 1761 0 0 0 0 0 0 0 0 0 ORF 2017 2 0 0 0 0 2 0 0 0 ORF 2074 2 0 0 0 2 2 2 0 0 ORF 2076 2 0 0 0 2 2 2 0 0 ORF 2110 0 0 0 0 0 0 0 0 0 ORF 2372 0 0 0 0 0 0 0 0 0 ORF 2541 0 0 0 0 0 0 0 0 0 ORF 2579 2 0 0 0 2 2 0 0 0 ORF 2777 0 0 0 0 0 0 0 0 0 ORF 2819 0 0 0 0 0 0 0 0 0 ORF 2847 0 0 0 0 0 0 0 0 0 ORF 2858 2 2 0 0 0 2 0 2 2 ORF 3103 2 0 0 0 2 0 0 0 0 ORF 3184 2 0 0 0 2 0 0 0 0 ORF 3401 2 0 0 0 0 2 0 0 0 ORF 3792 0 0 0 0 0 0 0 0 0 ORF 3840 0 0 0 0 0 0 0 0 0 ORF 4101 2 2 0 0 2 2 2 0 0 ORF 660 0 0 0 0 0 0 0 0 0 ORF 757 2 2 0 0 2 0 0 0 0 ORF 799 2 2 0 0 2 2 2 0 0 ORF 817 0 2 0 0 0 0 0 0 0

TABLE 17 L. monocytogenes Lineage Lineage Lineage Lineage I I II II Lineage Lineage I.1 I.2 II.1 II.2 III III L. 1/2a- 1/2c- 1/2b- 4b- III.1 III.2 L. L. L. L. grayi- 3a 3c 3b-7 4d-4e 4a 4c ivanovii welshimeri seeligeri innocua murray Strains strains strains strains strains strains Gene description Gene function category a: Percentage of presence of a specific gene in the different Listeria species and L. monocytogenes sub-groups L. monocytogenes EGDe genes Lmo0082 0 0 0 0 0 100 100 100 100 100 100 108aa/Unknwon unknown Lmo0083 0 0 0 0 0 100 100 100 100 100 100 122aa/unknown, similar to transcription Regulation regulator (merR family) Lmo0200 50 0 50 25 100 100 100 100 100 100 100 237aa/prfA: listeriolysin positive Regulation regulatory protein Lmo0201 0 0 0 0 0 100 100 100 100 100 100 317aa/plcA: phosphatidylinositol-specific virulence phospholipase c Lmo0202 83 0 50 0 0 100 100 100 100 100 100 529aa/hly virulence Lmo0203 50 0 0 0 0 100 100 100 100 100 100 510aa/mpl: Zinc matalloproteinase virulence precursor Lmo0204 0 0 0 0 0 100 100 100 100 100 100 639aa/actA: actin-assembly inducing virulence protein precursor Lmo0205 0 0 0 0 0 100 100 100 100 100 100 289aa/plcB: phospholipase C virulence Lmo0206 0 0 0 0 0 100 100 100 100 100 100 107aa/unknwon unknown Lmo0433 0 0 0 0 0 100 100 100 100 100 100 800aa/InlA: Internalin A cell surface proteins Lmo0434 0 0 0 0 0 100 100 100 100 100 100 630aa/InlB: Internalin B cell surface proteins Lmo0440 0 0 0 0 0 100 100 100 100 100 100 167aa/unknown unknown Lmo0550 0 0 0 13 0 100 100 100 100 100 100 98aa/unknown, pepdidoglycan bound cell surface proteins protein (LPXTG motif) Lmo0733 0 0 0 0 0 100 100 100 100 100 100 169aa/unknown, similar to transcription Regulation regulator Lmo1133 0 0 0 0 0 100 100 100 100 100 100 102aa/unknown, similar to B. subtilis YjcS unknown protein Lmo2732 0 0 0 0 0 100 100 100 100 100 100 250aa/unknwon unknown Lmo2733 0 0 0 0 0 100 100 100 100 100 100 652aa/unknown, similar to PTS system, Transport/binding proteins fructose-specific IIABC component and lipoproteins Lmo2734 0 0 0 0 0 100 100 100 100 100 100 882aa/unknown, weakly similar to sugar Specific pathways hydrolase Lmo2736 0 0 0 0 0 100 100 100 100 100 100 377aa/unknown, conserved hypothetical unknown protein Lmo0160 0 0 0 13 0 100 100 100 96 100 100 571aa/unknown, putative peptidoglycan Cell surface proteins bound protein (LPXTG motif) Lmo0833 0 0 0 0 0 100 100 100 100 33 100 296aa/unknown; similar to transcriptional Regulation regulator Lmo1135 0 0 0 0 0 100 100 100 100 33 100 383aa/unknwon unknown Lmo0017 0 0 0 0 0 100 100 100 100 0 100 372aa/unknown, similar to Bacillus Cell wall anthracis CapA protein (polyglutamate capsule biosynthesis) Lmo0263 0 0 0 0 0 100 100 100 100 0 100 548aa/InlH: Internalin H cell surface proteins Lmo0264 0 0 0 0 0 100 100 100 100 0 100 499aa/InlE: Internalin E cell surface proteins Lmo0333 0 0 0 0 0 100 100 100 100 0 100 1778aa/unknown, similar to internalin cell surface proteins proteins, putative peptidoglycan bound protein (LPXTG motif) Lmo0334 0 50 0 0 0 100 100 100 100 0 100 174aa/unknwon unknown Lmo0419 0 100 0 0 0 100 100 100 100 0 100 184aa/unknown, similar to unknown unknown protein Lmo0549 0 0 0 0 0 100 100 100 100 0 100 673aa/unknown, similar to internalin cell surface proteins protein Lmo0834 0 0 0 0 0 100 100 100 100 0 100 237aa/Unknwon unknown Lmo2821 0 0 0 0 0 100 100 100 100 0 100 851aa/unknown, similar to internalin, Cell surface proteins unknown, putative peptidoglycen bound protein (LPXTG motif) Lmo1786 100 0 0 0 0 100 100 100 100 0 50 296aa/InlC cell surface proteins Lmo0094 0 0 0 0 0 100 100 100 100 0 0 186aa/unknwon unknown Lmo0832 0 0 0 0 0 100 100 100 100 0 0 94aa/unknown, similar to transposase Transposon and IS Lmo0835 0 0 0 0 0 100 100 100 100 0 0 334aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo1441 0 0 0 0 0 100 100 100 100 0 0 368aa/unknown, similar to putative Cell wall peptidoglycan acetylation protein Lmo1451 0 0 0 0 0 100 100 100 100 0 0 331aa/unknown, similar to E. coli LytB unknown protein Lmo1666 0 0 50 0 0 100 100 100 100 0 0 1711aa/unknown, peptidoglycan linked cell surface proteins protein (LPxTG) Lmo0933 67 100 100 50 0 100 100 100 0 0 0 315aa/unknown, similar to sugar Cell wall transferase Lmo1090 0 0 100 0 0 100 100 100 0 0 50 327aa/unknown, similar to Cell wall glycosyltransferases Lmo0497 0 0 0 0 0 100 100 100 4 0 0 502aa/unknown, similar to sugar Cell wall transferase Lmo1076 0 0 100 0 0 100 100 100 0 0 0 572aa/unknown, similar to AUTOLYSIN Cell wall (EC 3.5.1.28) (N-ACETYLMURAMOYL-L- ALANINE AMIDASE) Lmo1077 0 0 100 0 100 100 100 100 0 0 0 562aa/unknown, similar to teichoic acid Cell wall biosynthesis protein B Lmo1079 0 0 100 0 0 100 100 100 0 0 0 952aa/unknown, similar to B. subtilis YfhO unknown protein Lmo1080 0 0 50 0 0 100 100 100 0 0 0 623aa/unknown, similar to B. subtilis Cell wall minor teichoic acids biosynthesis protein GgaB Lmo1081 0 0 100 0 0 100 100 100 0 0 0 288aa/unknown, similar to glucose-1- Cell wall phosphate thymidyl transferase Lmo1082 0 0 100 0 0 100 100 100 0 0 0 186aa/unknown, similar to dTDP-sugar Cell wall epimerase Lmo1083 0 0 100 0 0 100 100 100 0 0 0 328aa/unknown, similar to dTDP-D- Cell wall glucose 4,6-dehydratase Lmo1084 0 0 100 0 0 100 100 100 0 0 0 276aa/unknown, similar to DTDP-L- Cell wall rhamnose synthetase Lmo1085 0 0 0 0 0 100 100 100 0 0 0 696aa/unknown, similar to teichoic acid Cell wall biosynthesis protein B Lmo1088 0 0 50 0 0 100 100 100 0 0 0 386aa/tagB: unknown, similar to teichoic Cell wall acid biosynthesis protein B precursor Lmo1091 0 0 100 0 0 100 100 100 0 0 0 337aa/unknown, slumilar to Cell wall glysosyltransferases Lmo0171 0 0 0 0 0 100 100 0 0 0 0 832aa/unknwon, similar to internalin cell surface proteins proteins, putative peptidoglycan bound protein (LPXTG motif) Lmo0172 0 0 0 0 0 100 100 0 0 0 0 112aa/unknown, similar to transposase C- Transposon and IS terminal part Lmo0525 0 50 0 0 0 100 100 0 0 0 0 443aa/unknwon unknown Lmo0734 0 100 0 0 0 100 100 0 0 0 0 334aa/unknown, similar to transcriptional Regulation regulator (Lacl family) Lmo0735 17 50 0 0 0 100 100 0 0 0 0 223aa/unknown, similar to Ribulose-5- Specific pathways Phosphate 3-Epimerase Lmo0736 67 100 0 0 0 100 100 0 0 0 0 148aa/unknown, similar to ribose 5- Specific pathways phosphate isomerase Lmo0737 0 0 0 0 0 100 100 0 0 0 0 310aa/Unknwon unknown Lmo0738 33 0 0 0 0 100 100 0 0 0 0 617aa/unknown, similar to Transport/binding proteins phosphotransferase system (PTS) beta- and lipoproteins glucoside-specific enzyme IIABC component Lmo0739 0 0 0 0 0 100 100 0 0 0 0 457aa/unknown, similar to 6-phospho-beta- Specific pathways glucosidase Lmo1060 0 100 0 0 0 100 100 0 0 0 0 220aa/unknown, similar to transcription Regulation response regulator Lmo1061 0 50 0 0 0 100 100 0 0 0 0 481aa/unknown, similar to sensor protein Sensors (signal transduction) histidine kinases (2 components regulatory systems) Lmo1062 0 100 0 0 0 100 100 0 0 0 0 473aa/unknown, unknown, similar to ABC Transport/binding proteins transporters (permease protein) and lipoproteins Lmo1063 0 100 0 0 0 100 100 0 0 0 0 222aa/unknown, similar to ABC Transport/binding proteins transporter (ATP binding protein) and lipoproteins Lmo1968 0 0 0 13 0 100 100 0 0 0 0 247aa/unknown, similar to creatinine Metabolism of amino acids amidohydrolases and related molecules Lmo1969 0 0 0 13 0 100 100 0 0 0 0 202aa/unknown, similar to 2-keto-3- Specific pathways deoxygluconate-6-phosphate aldoiase Lmo1970 0 0 0 13 0 100 100 0 0 0 0 305aa/unknown, similar to putative Metabolism of lipids phosphotriesterase related proteins Lmo1971 0 0 0 13 0 100 100 0 0 0 0 422aa/unknown, similar to pentitol PTS Transport/binding proteins system enzyme II C component and lipoproteins Lmo1973 0 0 0 13 0 100 100 0 0 0 0 147aa/unknown, similar to PTS system Transport/binding proteins enzyme II A component and lipoproteins Lmo1974 0 0 0 13 0 100 100 0 0 0 0 249aa/unknown, similar to transcription Regulation regulators, (GntR family) Lmo0151 0 0 0 0 0 11 100 0 0 0 0 135aa/unknwon unknown Lmo0466 0 0 0 0 0 11 100 0 0 0 0 567aa/unknown unknown Lmo0467 0 0 0 0 0 11 100 0 0 0 0 107aa/unknwon unknown Lmo0469 0 0 0 0 0 11 100 0 0 0 0 290aa/unknwon unknown Lmo0470 0 0 0 0 0 11 100 0 0 0 0 209aa/unknown, weakly similar to site- DNA restriction/modification specific DNA-methyltransferase and repair Lmo0471 0 0 0 0 0 11 100 0 0 0 0 336aa/unknwon unknown Lmo1118 17 0 0 0 0 4 100 0 0 0 0 505aa/unknwon unknown Lmo1119 0 0 0 0 0 4 100 0 0 0 0 285aa/unknown, similar to methylases DNA restriction/modification and repair Lmo0752 100 0 0 0 0 100 100 100 100 100 0 278aa/unknown, weakly similar to a Detoxification putative haloacetate dehalogenase Lmo0753 100 0 0 0 0 100 100 100 100 100 0 226aa/unknown, similar to transcription Regulation regulator Crp/Fnr family Lmo0754 100 0 0 0 0 100 100 100 100 100 0 203aa/unknown, weakly similar to a bile Detoxification acid 7-alpha dehydratase Lmo1030 100 0 0 0 0 100 100 100 100 0 100 342aa/unknown, similar to transcriptional Regulation regulator, Lacl family Lmo1031 100 0 0 0 0 100 100 100 100 0 100 467aa/unknown, similar to hypothetical unknown proteins Lmo1033 100 0 0 0 0 100 100 100 100 0 100 318aa/unknown, similar to transketolase Specific pathways Lmo1034 100 0 0 0 0 100 100 100 100 0 100 487aa/unknown, similar to glycerol kinase Specific pathways Lmo1035 100 0 0 0 0 100 100 100 100 0 100 618aa/unknown, similar to Transport/binding proteins phosphotransferase system (PTS) beta- and lipoproteins glucoside-specific enzyme IIABC Lmo1036 100 0 0 0 0 100 100 100 100 0 100 421aa/unknwon unknown Lmo2157 100 0 0 0 0 100 100 100 100 0 100 633aa/SepA-unknown unknown Lmo0066 50 0 0 25 0 22 100 15 7 33 100 604aa/unknwon, similar to toxin miscellaneous components Lmo0067 0 0 0 25 0 7 100 10 0 0 0 329aa/unknown, similar to dinitrogenase Protein modification reductase ADP-ribosylation system Lmo0068 0 0 0 25 0 7 100 45 59 0 0 107aa/unknwon unknown Lmo0069 0 0 0 0 0 19 100 80 59 0 0 97aa/unknwon unknown Lmo0071 0 0 0 0 0 19 100 95 59 0 0 85aa/Unknwon unknown Lmo0072 0 0 0 25 0 41 100 90 100 0 0 67aa/unknown, Hypothetical unknown Lmo0073 0 0 0 0 0 11 100 50 59 0 0 94aa/unknwon unknown Lmo0074 0 0 0 0 0 11 100 45 59 0 0 149aa/unknwon unknown Lmo0079 33 0 50 0 0 67 92 100 81 0 100 492aa/unknown unknown Lmo0080 0 0 50 0 0 48 100 95 85 0 0 132aa/unknwon unknown Lmo0081 0 0 0 0 0 15 92 35 0 0 0 200aa/unknwon unknown Lmo0141 0 0 0 0 0 30 100 25 96 100 50 80aa/unknwon unknown Lmo0143 0 0 0 0 0 22 100 5 7 100 0 58aa/unknwon unknown Lmo0144 0 0 0 0 0 11 100 25 96 100 50 147aa/unknwon unknown Lmo0146 0 0 0 25 0 33 100 35 96 100 100 68aa/unknwon, hypothetical protein unknown Lmo0252 0 100 50 0 0 44 100 0 0 100 100 128aa/unknown, similar to repressor Regulation (penicilinase repressor) Lmo0253 0 0 50 0 0 44 100 0 0 100 100 346aa/unknown, similar to penicillinase Regulation antirepressor Lmo0255 0 0 0 0 0 93 100 30 22 100 100 167aa/unknown, similar to unknown unknown protein Lmo0262 0 0 0 0 0 63 100 0 4 0 100 490aa/InIG cell surface proteins Lmo0304 0 50 0 50 0 56 100 90 7 0 50 421aa/Unknwon unknown Lmo0310 0 0 0 0 0 7 100 30 4 0 0 358aa/unknown unknown Lmo0311 0 0 0 0 0 7 100 30 4 0 0 206aa/unknwon unknown Lmo0312 0 0 0 0 0 7 100 30 4 0 0 400aa/unknown, similar to unknown unknown proteins Lmo0313 0 0 0 0 0 7 100 30 4 0 0 248aa/unknown, conserved hypothetical unknown protein Lmo0320 0 0 0 13 0 85 100 90 100 33 0 399aa/unknown, similar to surface protein cell surface proteins (peptidoglycan bound, LPXTG motif) Lmo0338 33 0 0 13 50 67 100 0 0 0 0 126aa/unknwon unknown Lmo0378 0 0 0 50 0 100 92 75 19 0 0 148aa/unknown unknown Lmo0379 0 0 0 25 0 85 100 0 0 0 100 151aa/unknwon unknown Lmo0380 0 0 0 25 0 96 92 75 19 0 100 209aa/unknwon unknown Lmo0361 0 0 0 25 0 100 100 75 19 100 0 128aa/unknwon unknown Lmo0409 0 0 0 0 0 78 100 60 78 0 0 821aa/InIF internalin, putative cell surface proteins peptidoglycan bound protein (LPXTG motif) Lmo0444 0 100 0 0 0 37 100 65 0 0 100 926aa/unknown, conserved hypothetical unknown protein Lmo0445 0 100 0 0 0 44 100 65 0 0 100 495aa/unknown, similar to transcription Regulation regulator Lmo0446 0 100 0 0 0 44 92 65 0 0 100 329aa/unknown, similar to penicillin Detoxification acylase and to conjugated bile acid hydrolase Lmo0447 50 100 50 0 0 44 100 65 0 0 100 462aa/unknown, similar to glutamate Metabolism of amino acids decarboxylase and related molecules Lmo0448 0 100 0 63 0 44 100 95 63 33 100 483/unknown, similar to amino acid Transport/binding proteins antiporter and lipoproteins Lmo0459 0 0 0 0 0 48 100 100 100 100 50 512aa/unknown, similar to transcription Regulation regulator (VirR from Streptococcus pyogenes) Lmo0460 0 0 0 0 0 48 100 100 100 100 50 689aa/unknown, putative membrane cell surface proteins associated lipoprotein Lmo0462 0 0 0 0 0 48 92 100 100 100 50 161aa/unknwon unknown Lmo0472 0 50 0 88 0 81 100 25 4 0 100 295aa/unknwon unknown Lmo0473 67 50 0 38 0 93 100 20 67 100 100 361aa/unknwon unknown Lmo0474 0 0 0 25 0 93 100 10 100 0 0 115aa/unknwon unknown Lmo0477 17 50 0 63 0 89 100 20 63 0 50 125aa/unknown, putative secreted protein unknown Lmo0478 33 50 0 75 0 93 100 25 63 0 50 125aa/unknown, putative secreted protein unknown Lmo0492 0 0 0 0 0 85 100 95 100 0 50 302aa/unknown, similar to transcriptional Regulation regulator (LysR family) Lmo0493 67 0 100 0 0 85 100 100 100 0 50 586aa/unknown, similar to acylase Detoxification Lmo0630 50 100 0 0 0 100 100 95 81 0 50 676aa/unknown, similar to transcription Regulation antiterminator BglG family Lmo0631 0 100 0 0 0 100 100 100 81 0 50 150aa/unknown, similar to PTS system, Transport/binding proteins fructose-specific IIA component and lipoproteins Lmo0632 100 100 0 0 0 100 100 100 81 0 50 353aa/unknown, similar to PTS system, Transport/binding proteins fructose-specific IIC component and lipoproteins Lmo0633 100 100 0 0 0 100 100 95 81 0 50 102aa/unknown, similar to PTS system, Transport/binding proteins fructose-specific IIB component and lipoproteins Lmo0634 83 100 0 0 0 100 100 100 81 0 50 422aa/unknown, similar to an E. coli Specific pathways putative tagatose 6-phosphate kinase Lmo0745 0 0 0 0 0 96 100 0 0 100 0 167aa/unknown unknown Lmo0750 0 0 0 0 0 100 100 0 4 100 0 171aa/unknwon unknown Lmo0751 17 0 0 0 0 96 100 60 81 100 0 98aa/unknwon unknown Lmo0780 33 50 0 0 0 100 100 15 7 100 100 115aa/unknown unknown Lmo0801 0 50 50 13 0 70 100 0 30 33 0 646aa/unknown, similar to internalin, cell surface proteins putative peptidoglycan bound protein (LPXTG motif) Lmo0804 0 0 0 0 0 44 100 45 33 100 100 156aa/Unknwon unknown Lmo0842 17 100 0 75 0 100 100 95 48 33 0 2044aa/unknown, surface protein (LPXTG cell surface proteins motif) Lmo1032 100 0 0 0 0 100 92 100 100 0 100 274aa/unknown, similar to transketoiase Specific pathways Lmo1099 17 0 0 0 0 11 50 5 19 0 50 139aa/unknown, similar to a protein Transposon and IS encoded by Tn916 Lmo1106 33 0 0 50 0 63 67 35 30 33 100 816aa/unknown, highly similar to TN916 Transposon and IS ORF16 Lmo1114 100 100 50 13 0 81 92 60 74 33 100 104aa/unknown, highly similar to TN916 Transposon and IS ORF23 Lmo1115 33 0 50 13 0 78 75 10 4 33 100 862aa/unknown, similar to fibrinogen- cell surface proteins binding protein (LPXTG motif) Lmo1116 67 0 0 63 0 48 100 60 81 0 50 257aa/unknown, similar to regulatory Regulation proteins Lmo1117 67 0 0 50 0 52 100 60 81 0 50 118aa/unknown unknown Lmo1120 67 50 50 25 0 85 100 95 85 0 0 138aa/unknwon unknown Lmo1121 17 100 0 50 0 96 100 95 85 33 50 122aa/unknwon unknown Lmo1125 67 50 0 25 0 100 100 0 0 100 100 177aa/unknown unknown Lmo1307 33 50 0 0 0 100 100 0 0 100 100 280aa/unknwon unknown Lmo1597 67 100 0 0 0 63 100 85 19 0 0 259aa/unknwon unknown Lmo1604 33 0 0 75 0 100 100 75 67 33 100 181aa/unknown unknown Lmo1648 17 50 0 25 0 78 100 20 7 0 50 120aa/unknwon unknown Lmo1714 0 0 0 25 0 41 100 100 100 100 0 190aa/unknown unknown Lmo2026 0 0 0 0 0 41 100 0 0 0 0 626aa/unknown, peptidoglycan linked cell surface proteins proteins (LPXTG) Lmo2027 0 0 0 0 0 93 100 75 70 0 100 367aa/unknown, putative cell surface cell surface proteins protein, similar to internalin proteins Lmo2276 0 0 0 0 0 78 75 70 67 0 0 165aa/unknown, similar to an unknown Phage-related functions bacteriophage protein Lmo2277 17 0 0 25 0 56 42 10 11 33 50 183aa/unknwon unknown Lmo2278 0 0 50 0 0 89 100 90 0 0 0 281aa/LysA: L-alanoyl-D-glutamate Phage-related functions peptidase Lmo2282 0 0 0 25 0 33 25 55 4 33 0 105aa/protein gp21 [Bacteriophage A118] Phage-related functions Lmo2283 0 0 0 0 0 37 25 55 0 0 0 357aa/protein gp20 [Bacteriophage A118] Phage-related functions Lmo2296 0 0 0 25 0 15 33 15 26 100 0 333aa/unknown, similar to coat protein Phage-related functions [Bacteriophage SPP1] Lmo2311 0 0 0 0 0 41 75 5 0 100 50 153aa/unknwon unknown Lmo2312 0 50 0 25 0 56 75 80 33 100 0 156aa/unknwon unknown Lmo2313 0 50 0 13 0 59 50 45 33 67 0 147aa/unknown, similar to a bacteriophage Phage-related functions protein Lmo2319 0 50 50 13 0 33 92 15 19 0 0 158aa/unknown, similar to a bacteriophage Phage-related functions proteins Lmo2322 0 0 0 63 0 48 50 25 0 0 0 71aa/gp44 [Bacteriophage A118] Phage-related functions Lmo2324 0 50 0 38 0 63 83 35 41 67 0 258aa/unknown, similar to anti-repressor Regulation [Bacteriophage A118] Lmo2408 0 100 0 0 0 37 100 0 0 0 0 67aa/unknown, similar to repressor Regulation protein Lmo2409 0 50 0 0 0 33 100 0 0 0 0 137aa/unknwon unknown Lmo2410 0 0 0 0 0 33 100 0 0 0 0 183aa/unknown unknown Lmo2443 0 0 0 0 0 89 100 95 100 100 0 139aa/unknwon unknown Lmo2576 0 0 0 0 0 100 100 0 0 0 100 1530aa/unknwon, peptidoglycan anchored cell surface proteins protein (LPXTG motif) Lmo2594 0 0 0 50 0 74 92 80 100 33 100 119aa/unknwon unknown Lmo2595 0 0 0 0 0 52 100 40 100 100 50 289aa/unknown, similar to unknown unknown proteins Lmo2671 17 100 50 0 0 100 100 100 100 0 0 122aa/unknwon unknown Lmo2686 17 0 0 0 0 93 100 5 0 0 50 177aa/unknwon unknown Lmo2786 0 0 0 0 0 100 100 0 0 0 100 327aa/bvrC: unknown unknown Lmo2787 0 0 0 0 0 100 100 0 0 0 100 640aa/bvrB-beta-glucoside-specific Transport/binding proteins phosphotransferase enzyme II and lipoproteins Lmo2807 17 0 50 13 0 63 100 15 48 67 0 127aa/unknown, hypothetical secreted unknown protein Lmo2809 0 0 50 25 0 70 92 100 44 0 0 126aa/unknown, hypothetical secreted unknown protein Lmo0036 100 0 50 0 100 100 100 100 100 0 0 341aa/unknown, similar to ornithine Metabolism of amino acids carbamoyltransferase and related molecules Lmo0037 100 0 50 0 0 100 100 100 100 0 0 461aa/unknown, similar to amino acid Transport/binding proteins transporter and lipoproteins Lmo0038 100 0 50 0 0 100 100 100 100 0 0 363aa/unknown, conserved hypothetical unknown protein Lmo0039 100 0 50 0 0 100 100 100 100 0 0 313aa/carbamate kinase Metabolism of amino acids and related molecules Lmo0040 33 0 50 0 0 100 100 100 100 0 0 369aa/unknown, conserved hypothetical Phage-related functions protein Lmo0041 50 0 0 0 0 100 100 100 100 0 0 259aa/unknown, conserved hypothetical Regulation protein, hypothetical regulator Lmo0084 67 50 0 25 0 100 100 100 100 100 100 327aa/unknwon, similar to Specific pathways oxidoreductases Lmo0106 33 50 100 0 0 96 100 35 96 100 100 300aa/unknown, similar to transcription Regulation regulator Lmo0110 33 100 50 0 0 100 100 100 100 100 100 371aa/unknown, similar to lipase Metabolism of lipids Lmo0147 83 50 50 63 0 100 100 65 85 67 100 145aa/unknwon unknown Lmo0175 0 0 0 100 0 100 100 100 100 100 100 415aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo0461 83 0 100 0 0 81 92 100 100 100 100 157aa/unknwon unknown Lmo0463 0 0 0 0 0 56 100 100 100 100 50 101aa/putative peptidoglycan linked cell surface proteins protein (LPXAG motif) Lmo0476 67 100 50 75 0 93 100 100 100 100 50 325aa/unknown, similar to oxetanocin A Detoxification resistance protein oxrB Lmo0610 17 0 0 50 0 100 100 95 100 67 100 589aa/unknown, similar to internalin cell surface proteins proteins, putative peptidoglycan bound protein (LPXTG motif) Lmo0638 0 0 0 0 0 100 100 100 100 33 100 209aa/unknown unknown Lmo0673 83 0 50 75 0 100 100 100 100 100 100 69aa/unknwon unknown Lmo0732 50 50 0 75 0 100 100 80 70 100 100 638aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo0838 100 0 100 0 0 100 100 100 100 100 100 461aa/unknown, highly similar to hexose Transport/binding proteins phosphate transport protein and lipoproteins Lmo0849 33 0 0 13 0 100 100 100 100 33 100 616aa/unknown, similar to amidases Cell wall Lmo1102 100 0 50 13 0 78 100 65 76 100 100 111aa/unknown, similar to cadmium efflux Detoxification system accessory proteins Lmo1134 100 0 100 0 0 100 100 100 100 100 100 115aa/unknown, similar to regulatory Regulation proteins Lmo1247 0 0 0 100 0 100 100 100 100 100 100 87aa/unknwon unknown Lmo1263 50 0 0 13 0 100 100 100 100 100 100 71aa/unknown, similar to transcriptional Regulation regulator Lmo1413 0 0 50 0 0 100 100 100 100 100 100 439aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo1478 33 0 0 0 0 100 100 100 100 100 100 145aa/unknown, similar to transcriptional Regulation regulator (MerR family) Lmo1656 100 100 50 50 0 100 100 100 100 100 100 143aa/unknwon unknown Lmo2045 0 0 50 50 0 100 100 100 100 100 100 128aa/unknwon unknown Lmo2067 50 0 100 0 0 100 100 100 100 100 100 325aa/unknown, similar to conjugated bile Detoxification acid hydrolase Lmo2085 0 50 50 0 0 100 100 100 100 100 100 562aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo2143 17 0 0 0 0 100 100 100 100 100 100 580aa/unknown, weakly similar to Specific pathways mannose-6-phosphate isomerase Lmo2144 17 0 0 0 0 100 100 100 100 100 100 244aa/unknown, similar to transcription Regulation regulator GntR family Lmo2178 17 100 0 100 0 100 100 100 100 100 100 1612aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo2197 17 0 100 25 0 100 100 100 100 100 100 114aa/unknwon unknown Lmo2387 33 0 0 0 0 100 100 100 100 100 100 408aa/unknown, conserved hypothetical unknown protein Lmo2567 0 100 0 100 0 100 100 100 100 100 100 66aa/unknwon unknown Lmo2731 100 100 50 100 0 100 100 100 100 100 100 122aa/unknown, similar to transcription Regulation regulator (RpiR family) Lmo2735 33 0 0 25 0 100 100 100 100 100 100 560aa/unknown, similar to Sucrose Specific pathways phosphorylase Lmo2771 17 100 50 0 0 100 100 100 100 0 100 482aa/unknown, similar to beta- Specific pathways glucosidase Lmo2773 0 100 0 0 0 100 100 100 100 0 100 279aa/unknwon, similar to transcription Regulation antiterminator Lmo2776 0 0 0 63 0 74 100 100 100 33 100 131aa/unknwon unknown Lmo2781 50 100 50 0 0 100 100 100 100 100 100 756aa/unknown, similar to beta- Specific pathways glucosidase Lmo2782 67 100 0 0 0 100 100 100 100 100 100 99aa/unknown, similar to PTS, cellobiose- Transport/binding proteins specific IIB component and lipoproteins Lmo0257 100 100 50 50 0 100 100 100 100 100 100 392aa/unknown, similar to unknown unknown protein Lmo0514 67 100 100 68 0 100 100 100 100 100 100 605aa/unknown, similar to internalin cell surface proteins proteins, putative peptidoglycan bound protein (LPXTG motif) Lmo0843 100 100 100 100 0 100 100 100 100 100 100 85aa/unknown, similar to B. subtilis unknown protein YsdA Lmo0880 83 100 100 88 0 100 100 100 100 100 100 462aa/unknown, similar to wall associated cell surface proteins protein precursor (LPXTG motif) Lmo0932 100 100 100 100 0 100 100 100 100 100 100 201aa/unknown, conserved hypothetical unknown protein Lmo1136 100 100 100 100 100 100 100 100 100 100 100 539aa/unknown, similar to Internalin, cell surface proteins putative peptidoglycan bound protein (LPXTG motif) Lmo1289 83 50 100 63 50 100 100 100 100 100 100 593aa/unknown, similar to Internalin cell surface proteins proteins, putative peptidoglycan bound protein (LPXTG motif) Lmo1302 100 100 100 100 50 100 100 100 100 100 100 204aa/unknown, highly similar to SOS Regulation response regulator lexA, transcription repressor protein Lmo1303 100 100 100 88 50 100 100 100 100 100 100 109aa/unknown, similar to B. subtilis YneA unknown protein Lmo1700 83 100 100 100 0 100 100 100 100 100 100 68aa/unknwon unknown Lmo1707 100 100 100 100 0 100 100 100 100 100 100 73aa/unknwon unknown Lmo1799 100 100 50 88 0 100 100 100 100 100 100 903aa/unknown, putative peptidoglycan cell surface proteins bound protein (LPXTG motif) Lmo2451 100 100 100 100 0 100 100 100 100 100 100 77aa/unknown, similar to preprotein Protein secretion translocase subunit SecG Lmo2548 100 100 100 100 0 100 100 100 100 100 100 81aa/rpmE: ribosomal protein L31 Ribosomal proteins Lmo2772 33 100 100 0 0 100 100 100 100 0 100 617aa/unknown, similar to beta-glucoside- Transport/binding proteins specific enzyme IIABC and lipoproteins Lmo1097 0 0 0 13 0 11 0 5 0 0 0 400aa/unknown, similar to integrases Transposon and IS Lmo1101 0 0 0 13 0 19 8 5 7 0 0 166aa/unknown, similar to lipoprotein Protein secretion signal peptidase Lmo1103 0 0 0 0 50 11 8 0 0 0 0 305aa/unknown, highly similar to TN916 Transposon and IS ORF13 Lmo1104 0 0 0 25 0 7 0 0 0 0 0 336aa/unknown, highly similar to TN916 Cell wall ORF14 and to L. monocytogenes P60 protein Lmo1105 0 0 0 0 0 7 0 0 0 0 0 719aa/unknown, highly similar to TN916 Transposon and IS ORF15 Lmo1107 0 0 0 38 0 7 8 0 0 0 0 131aa/unknown, highly similar to TN916 Transposon and IS ORF17 Lmo1108 0 0 0 0 0 11 8 0 0 0 0 166aa/unknown, highly similar to TN916 Transposon and IS ORF18 Lmo1110 0 0 0 0 0 7 8 0 0 0 0 96aa/unknown, similar to unknown unknown proteins Lmo1111 0 0 0 0 0 7 8 0 0 0 0 394aa/unknown, highly similar to TN916 Transposon and IS ORF20 Lmo1112 17 50 0 13 0 15 17 5 7 0 0 466aa/unknown, highly similar to TN916 Transposon and IS ORF21 Lmo1113 0 0 0 13 0 11 25 5 0 0 0 124aa/unknown, highly similar to TN916 Transposon and IS ORF22 Lmo2301 0 0 0 0 0 22 17 0 0 0 0 264aa/unknown, similar to putative Phage-related functions terminase small subunit from Bacteriophage A118 Lmo2302 0 0 0 0 0 7 0 30 15 0 0 179aa/unknown unknown Lmo2318 0 0 0 0 0 4 0 5 7 0 0 232aa/unknwon unknown Lmo2331 0 0 0 0 0 22 25 15 0 0 0 226aa/unknown, weakly similar to Phage-related functions gp32_Bacteriophage A118 protein b: Percentage of presence of a specific gene in the different Listeria species and L. monocytogenes sub-groups L. monocytogenes (CLIP 80459) ORF 2372 33 100 0 0 0 0 0 0 100 0 0 596pb/unknown, similar titelchoic cell wall acid biosynthesis protein C ORF 2110 67 50 0 0 0 0 0 0 100 0 0 597pb/unknown, similar to unknown hypothetical protein ORF 799 0 50 0 63 0 7 0 0 100 0 0 453pb/unknown unknown ORF 3840 17 0 0 0 0 0 0 100 100 0 0 593pb/unknown, similar to Regulation transcription regulator ORF 2568-2569 50 0 0 0 0 0 0 100 100 0 0 597pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif)-unknown ORF 2017a 0 0 0 0 0 0 0 100 100 0 0 599pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 29 0 0 0 0 0 0 0 95 100 0 0 609pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 2819 0 0 0 0 0 0 0 100 100 0 0 562pb/unknown, similar to Regulation transcriptional regulator ORF 2541 0 0 0 0 0 30 0 100 100 0 0 590pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 2017b 50 0 0 25 0 26 0 100 100 33 100 285pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 3401 33 0 0 25 0 11 0 50 100 33 0 575pb/unknown unknown ORF 2074 100 100 50 50 0 48 0 100 100 100 0 599pb/unknown similar to Specific pathways oligo-1,6-glucosidase ORF528-529 0 0 0 13 0 0 0 10 100 0 0 591pb/unknown-unknown unknown ORF 150 100 100 100 63 100 89 92 95 100 100 100 393pb/unknown, similar to cell wall amidase ORF 2777 50 50 100 0 0 33 0 100 100 0 0 600pb/unknown unknown ORF 2759 100 100 50 38 0 52 0 95 100 100 0 601pb/unknown, sucrose Specific pathways phosphorylase ORF 75 100 100 100 100 100 100 100 100 100 100 100 504pb/unknown unknown ORF 660 0 0 0 0 0 33 0 10 100 0 0 603pb/unknown unknown ORF 2885 0 100 0 63 0 0 0 0 100 100 50 592pb/unknown unknown ORF 1445 50 0 0 0 0 0 0 0 100 100 100 607pb/unknown, conserved unknown hypothetical protein ykcB - Bacillus subtilis ORF 1590 0 0 0 0 0 100 0 95 100 0 100 588pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 1491 33 100 100 0 0 0 0 100 100 0 100 598pb/unknown, similar to unknown hypothetical protein ORF 1490 33 100 100 0 0 0 0 100 100 0 100 600pb/unknown, similar to Transport/binding sucrose-specific PTS system proteins and IIBC component lipoproteins ORF 1391 67 100 100 88 0 100 100 100 100 100 100 600pb/unknown unknown ORF 3792 17 0 0 0 0 67 17 100 100 100 100 594pb/unknown unknown ORF 4101 67 100 0 75 0 59 42 95 100 33 100 613pb/unknown, similar to Transport/binding similar to ABC transporter proteins and lipoproteins ORF 1490 33 100 100 0 100 4 0 100 100 0 100 474pb/unknown, similar to Transport/binding sucrose phosphotransferase proteins and enzyme IIBC component lipoproteins ORF2969-2968 83 100 100 88 0 93 100 90 100 100 100 583pb/unknown-unknown unknown ORF 148-149 0 0 0 0 0 0 0 10 100 0 0 620pb/unknown-unknown, cell wall similar to amidase ORF 3175 100 100 100 100 0 100 100 100 100 100 100 589pb/unknown, similar to Phage-related phage protein functions ORF 2858 50 50 50 50 100 74 75 90 100 33 100 249pb/unknown, similar to unknown hypothetical protein ORF 2541 17 0 0 0 0 41 0 95 100 0 100 351pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 757 0 0 0 38 0 4 0 35 100 0 0 522pb/unknown unknown ORF 2076 100 100 50 50 0 48 0 100 100 100 0 597pb/unknown, similar to Transport/binding maltodextrin ABC proteins and transporter lipoproteins ORF 2013 0 0 0 0 0 37 0 95 100 100 0 597pb/unknown, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF 1228 17 0 0 0 0 7 0 100 96 0 0 599pb/unknown, similar to Transport/binding similar to ABC transporter proteins and lipoproteins ORF 3184 33 50 0 25 0 26 33 70 96 33 50 597pb/unknown unknown ORF 2013 0 0 0 0 0 26 0 85 96 100 0 595pb/unknwon, similar to cell surface proteins internalin proteins, putative peptidoglycan bound protein (LPXTG motif) ORF1912-1913 33 50 50 0 0 26 8 15 93 100 100 602pb/unknown-unknown unknown ORF 2262 0 0 0 0 0 30 0 15 93 0 0 601pb/unknown unknown ORF 72-73-74 0 0 0 0 0 26 0 35 78 100 50 598pb/unknown-unknown unknown unknown ORF 2815 0 0 0 50 0 7 17 35 74 0 0 603pb/unknown, similar to unknown heat shock protein HtpG ORF 2847 0 0 0 0 0 7 0 0 74 100 0 590pb/similar to phage Phage-related integrase functions ORF 104-105 67 0 0 25 0 0 0 75 70 0 0 599pb/unknown, similar to Transport/binding similar to ABC transporter proteins and lipoproteins ORF 1390 33 0 50 25 0 26 8 15 56 67 0 624pb/unknown, similar to unknown hypothetical protein ORF1388-1387 17 0 0 0 0 11 0 10 41 100 50 600pb/unknown-unknown unknown ORF 182 0 0 0 25 0 22 0 0 41 0 0 468pb/unknown, similar to unknown B. subtilis YukA, ORF 3103 0 0 0 25 0 67 0 50 41 0 0 600pb/unknown, similar to cell wall peptidoglycan lytic protein P45 ORF 817 33 0 0 13 0 0 0 95 37 0 50 594pb/unknown unknown ORF 1384-1385 67 0 0 25 0 26 0 10 33 100 100 422pb/unknown-unknown unknown ORF 2884-2885 17 0 0 0 0 0 0 0 19 100 50 592pb/unknown unknown ORF 2217 0 0 0 0 0 0 0 0 15 0 0 602pb/unknown, imilar to DNA type II DNA modification restriction/modification enzyme and repair ORF 4457 0 0 0 0 0 0 0 0 15 0 0 588pb/unknown, DNA DNA double-strand break repair restriction/modification rad50 ATPase and repair c: Percentage of presence of a specific gene in the different Listeria species and L. monocytogenes sub-groups L. innocua (CLIP11262) genes Lin0739 0 0 0 100 0 0 0 0 0 0 0 521aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0803 0 0 0 100 0 0 0 0 0 0 0 1386aa/unknown, surface protein (LPXTG motif) cell surface proteins Lin2741 0 0 0 100 0 0 0 0 0 0 0 152aa/unknwon unknown Lin2918 0 0 0 100 0 0 0 0 0 0 0 159aa/unknwon unknown Lin0465 0 0 0 100 0 11 0 0 0 0 0 212aa/unknown, conserved hypothetical protein, unknown similar to yoaZ B. subtilis Lin1452 0 0 0 100 0 0 0 5 0 0 0 125aa/unknwon unknown Lin1811 0 0 0 100 0 4 0 0 0 0 0 323aa/unknown, similar to unknown proteins unknown Lin1813 0 0 0 100 0 4 0 0 0 0 0 620aa/unknown, similar to excinuclease ABC subunit A DNA restriction/modification and repair Lin1069 0 0 0 63 0 0 0 0 0 0 0 336aa/unknwon unknown Lin0332 0 0 0 38 0 0 0 0 0 0 0 405aa/unknown, similar to putative permeases Transport/binding proteins and lipoproteins Lin0338 0 0 0 38 0 0 0 0 0 0 0 266aa/unknwon unknown Lin0397 0 0 0 50 0 0 0 0 0 0 0 120aa/unknwon unknown Lin0868 0 0 0 50 0 0 0 0 0 0 0 378aa/unknwon unknown Lin1065 0 0 0 50 0 0 0 0 0 0 0 668aa/unknown, hypothetical protein unknown Lin1066 0 0 0 50 0 0 0 0 4 0 0 329aa/unknown, similar to dolichol phosphate Cell wall mannose synthase Lin1067 0 0 0 50 0 0 0 0 0 0 0 696aa/unknown unknown Lin1068 0 0 0 50 0 0 0 0 4 0 0 774aa/unknown, similar to hypothetical protein 3 Cell wall (capsulation locus) of Haemophilus Influenzae Lin1211 0 0 0 50 0 0 0 0 0 0 0 486aa/unknown unknown Lin0197 100 100 100 100 0 0 0 0 0 0 0 358aa/unknown, similar to chloromuconate Metabolism of cycloisomerase ykfB of B. subtilis carbohydrates (Specific pathways) Lin0198 33 50 0 100 0 0 0 0 0 0 0 292aa/unknown, P45 related protein Cell wall Lin0199 33 0 0 100 0 0 0 0 0 0 0 257aa/unknown, some similarities to probable beta- Detoxification lactamase Lin0372 0 0 0 100 0 70 75 100 100 100 100 656aa/unknown, probable cell surface protein cell surface (LPXTG motif) proteins Lin0415 0 100 50 100 0 70 75 70 78 0 100 410aa/unknown, probable cell surface protein cell surface (LPXTG motif) proteins Lin0453 0 100 0 100 0 0 0 0 100 0 0 169aa/unknown unknown Lin0454 17 100 0 100 0 0 0 0 100 100 100 2167aa/unknown, similar to cell wall-associated cell surface protein precursor wapA (B. subtilis) proteins Lin0455 33 50 0 100 0 0 0 0 67 100 50 184aa/unknwon unknown Lin0559 0 0 0 100 0 11 0 10 19 0 0 96aa/unknown, probable cell surface protein (LPXTG cell surface motif) proteins Lin0661 0 0 0 100 0 52 50 5 15 0 50 596aa/unknown, internalin like protein (LPXTG motif) cell surface proteins Lin0665 0 50 100 100 0 59 58 100 100 100 100 831aa/unknown, highly similar to ORFA of Listeria cell surface seeligeri, (LPXTG motif) proteins Lin0677 0 0 0 100 0 11 0 0 0 100 100 293aa/unknown, conserved hypothetical protein unknown Lin0740 0 0 0 100 0 74 75 40 30 67 100 657aa/unknown, probable cell surface protein Cell surface proteins (LPXTG motif) Lin1073 83 50 0 100 0 0 0 0 100 100 100 462aa/unknown, similar to galactosamine-containing Cell wall minor telchoic acid biosynthesis protein GgaA Lin1099 0 0 0 100 0 0 0 0 15 100 100 235aa/unknwon unknown Lin1299 33 0 50 100 0 78 92 70 78 67 100 121aa/unknwon unknown Lin1328 83 0 50 100 0 74 75 50 70 67 100 620aa/unknown, Internalin like protein (LPXTG motif) Cell surface proteins Lin2394 67 100 100 100 0 93 100 90 100 100 100 439aa/unknown unknown Lin2494 0 100 50 100 0 89 100 95 41 100 100 124aa/unknown, hypothetical protein unknown Lin2724 17 0 0 100 0 0 0 0 0 100 50 938aa/unknown, internalin-like protein (LPXTG motif) cell surface proteins Lin2744 17 50 50 100 0 67 67 75 7 0 100 1334aa/unknown, similar to hypothetical proteins unknown Lin2839 0 0 0 100 0 30 0 25 0 0 0 99aa/unknwon unknown Lin0065 33 0 0 88 0 74 75 45 74 33 100 136aa/unknwon unknown Lin0867 33 50 0 88 100 19 0 5 15 33 0 421aa/unknwon unknown Lin1084 17 50 100 88 0 59 0 100 85 0 0 94aa/unknwon unknown Lin1258-57 17 50 0 88 0 4 0 0 0 0 0 184aa-175aa/unknown unknown Lin1621 0 0 0 88 0 0 0 0 0 100 0 253aa/unknown, similar to ketoacyl reductases Metabolism of lipids Lin2743 17 50 50 88 0 52 0 60 0 0 50 98aa/unknwon unknown Lin0307 0 0 0 75 0 19 0 0 0 0 0 219aa/unknown, similar to ABC transporters (ATP- Transport/binding binding protein) proteins and lipoproteins Lin0308 0 0 0 75 0 15 0 0 0 0 0 261aa/unknown, similar to hypothetical proteins unknown Lin0398 33 50 50 75 0 0 0 10 0 67 0 536aa/unknwon unknown Lin0399 17 50 0 75 0 0 0 0 0 0 0 252aa/unknwon unknown Lin0865 17 0 0 75 0 15 8 0 11 33 50 131aa/unknown, hypothetical protein unknown Lin1090 67 0 0 75 0 0 0 100 100 67 100 111aa/unknwon unknown Lin1262 0 0 0 75 0 74 75 50 67 67 100 445aa/unknwon unknown Lin2397 0 50 50 75 0 41 33 30 11 0 0 190aa/unknown, similar to sigma factor-like positive RNA synthesis control protein of B. subtilis (Initiation) Lin2945 0 0 0 75 0 0 0 0 0 100 0 191aa/unknwon unknown Lin0060 0 0 0 63 0 4 0 15 22 0 0 204aa/unknown unknown Lin0062 0 0 0 63 0 7 0 10 0 0 0 210aa/unknown, hypothetical protein unknown Lin1204 0 0 0 63 0 0 0 90 100 100 0 1237aa/unknown, similar to internalin proteins Cell surface (LPXTG motif) proteins Lin2603 0 0 50 63 0 30 50 30 11 100 0 95aa/unknwon unknown Lin1212 0 0 0 50 0 11 0 0 4 0 50 184aa/unknwon unknown Lin2100 0 100 0 50 0 0 0 0 0 0 0 764aa/unknown, similar to p60-related proteins Cell wall Lin2405 0 0 0 50 0 4 8 20 4 0 0 69aa/unknwon unknown Lin2693 0 100 0 50 0 0 0 0 0 0 0 497aa/unknwon unknown Lin0064 0 0 0 38 0 0 0 10 33 0 0 129aa/unknwon unknown Lin0476 0 0 0 38 0 59 67 40 30 0 100 350aa/unknwon unknown Lin1082 0 0 0 38 0 0 0 0 0 0 0 387aa/unknwon unknown Lin1083 0 0 0 38 0 7 0 35 0 0 0 216aa/unknwon unknown Lin2383 0 50 50 38 0 63 58 35 11 0 0 1601aa/unknown, similar to hypothetical protein Phage-related [Lactobacillus casei bacteriophage A2] functions Lin2425 0 50 0 38 0 4 0 0 0 0 0 235aa/unknwon unknown Lin2604 17 0 50 38 0 52 83 40 7 100 0 80aa/unknwon unknown Lin2941 0 0 0 38 0 0 0 0 0 100 0 663aa/unknwon unknown Lin0478 0 0 0 25 0 0 0 0 0 0 0 407aa/unknwon unknown Lin0772 0 0 0 25 0 0 0 0 0 0 0 417aa/unknwon unknown Lin0801 0 0 0 25 0 0 0 0 0 0 0 240aa/unknown, similar to two-component response RNA synthesis regulators (Regulation) Lin0802 0 0 0 25 0 0 0 0 0 0 0 433aa/unknown, similar to two-component sensor Sensore (signal histidine kinases transduction) Lin0833 0 0 0 25 0 0 0 0 0 0 0 489aa/unknwon unknown Lin0834 0 0 0 25 0 0 0 0 0 0 0 369aa/unknown, some similarities to hypothetical unknown proteins Lin0835 0 0 0 25 0 0 0 0 0 0 0 285aa/unknwon unknown Lin1898 0 0 0 25 0 0 0 0 0 0 0 177aa/unknown, similar to putative NAD(P)H Membrane oxidoreductase bioenergetics (electron transport chain and ATP synthase) Lin2373 0 0 0 25 0 0 0 0 0 0 0 298aa/unknown, similar to AblD phage protein Phage-related functions Lin0035 0 0 0 13 0 4 0 0 26 0 0 219aa/unknown, similar to E. coli DedA protein unknown Lin0038 0 0 0 13 0 4 0 0 26 0 0 179aa/unknown, highly similar to single-strand DNA replication binding protein (SSB) Lin0072 0 0 0 13 0 4 0 20 0 0 0 216aa/unknwon unknown Lin0073 0 0 0 13 50 4 0 5 0 0 0 158aa/unknown, similar to a putative repressor Regulation protein [Bacteriophage A118] Lin1241 0 0 0 13 0 0 0 0 0 0 0 646aa/unknown, similar to bacteriophage protein Phage-ralated functions Lin1260 0 0 0 13 0 0 0 0 0 0 0 255aa/unknown, similar to probable antirepressor - Phage-related Bacillus subtilis phage SPBc2 functions Lin1300 100 0 50 13 0 0 0 0 0 100 100 203aa/unknwon unknown Lin1723 0 0 0 13 0 0 0 0 0 0 0 199aa/unknwon unknown Lin1728 0 0 0 13 0 4 0 0 0 0 0 369aa/unknown, similar to hypothetical proteins unknown Lin1731 0 0 0 13 0 4 0 0 0 0 0 461aa/unknown, some similarities to conserved unknown hypothetical proteins Lin1744 0 0 0 13 0 0 0 0 0 0 0 453aa/unknwon unknown Lin1745 0 0 0 13 0 0 0 0 0 0 0 140aa/unknown unknown Lin1747 0 0 0 13 0 0 0 0 0 0 0 125aa/unknwon unknown Lin1756 0 0 0 13 0 0 0 0 0 0 0 660aa/unknown, similar to hypothetical protein of unknown Staphylococcus aureus phage phi PVL 

1. An isolated nucleic acid comprising: a) a nucleotide sequence selected from SEQ ID NOS: 1-163; b) a fragment or variant of a nucleotide sequence selected from SEQ ID NOS: 1-163; c) a degenerate variant of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the degenerate variant encodes a polypeptide sequence selected from SEQ ID NOS: 164-326; or c) a fragment of a nucleotide sequence selected from SEQ ID NOS: 1-163, wherein the fragment is a forward or reverse primer shown in Table
 5. 2. A hybridization support comprising the nucleic acid of claim
 1. 3. A vector comprising the nucleic acid of claim
 1. 4. A recombinant cell comprising the vector of claim
 3. 5. An isolated polypeptide comprising: a) a polypeptide sequence selected from SEQ ID NOS: 164-326; or b) a fragment or variant of polypeptide sequence selected from SEQ ID NOS: 164-326.
 6. An isolated antibody that specifically binds to a polypeptide of claim
 5. 7. The isolated antibody according to claim 6, wherein the antibody is a monoclonal antibody.
 8. A hybridization support comprising an isolated polypeptide of claim
 5. 9. A hybridization support comprising an isolated antibody of claim
 7. 10. A method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the method comprises detecting a nucleic acid of claim 1 in the sample.
 11. A method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the method comprises: a) bringing the sample into contact with the hybridization support of claim 2; b) detecting a specific hybrid between the hybridization support and a nucleic acid of claim 1 in the sample.
 12. A method for identifying a L. monocytogenes in a sample, wherein the method comprises detecting a L. monocytogenes-specific nucleic acid sequence in the sample.
 13. The method of claim 12, wherein the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, plcA, actA, plcB, Imo206, inIA, inIB, Imo0440, Imo 0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, plcA, actA, plcB, Imo206, inIA, inIB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821.
 14. The method of claim 12, wherein the L. monocytogenes-specific nucleic acid sequence is inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.
 15. A method for identifying the lineage of a L. monocytogenes in a sample, wherein the method comprises detecting the absence or the presence of a L. monocytogenes lineage-specific nucleic acid sequence in the sample.
 16. The method of claim 15, wherein the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF
 1761. 17. The method of claim 15, wherein the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence.
 18. The method of claim 17, wherein the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 19. The method of claim 15, wherein the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence.
 20. The method of claim 19, wherein the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 21. The method of claim 15, wherein the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage III-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence.
 22. The method of claim 21, wherein the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.
 23. A method for sub-lineage typing of a L. monocytogenes in a sample, wherein the method comprises determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample.
 24. The method of claim 23, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises: a) a lineage I-specific nucleic acid sequence; b) a sublineage I.1- or I.2-specific nucleic acid sequence; c) a lineage II-specific nucleic acid sequence; and d) a sublineage II.1- or II.2-specific nucleic acid sequence.
 25. The method of claim 24, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence.
 26. The method of claim 25, wherein the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 27. The method of claim 25, wherein the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119.
 28. The method of claim 25, wherein the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 29. The method of claim 25, wherein the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment or variant of ORF 0799, ORF 2372 or ORF
 2110. 30. The method of claim 25, wherein the lineage I-specific nucleic acid sequence is Imo737 or a fragment thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment thereof.
 31. The method of claim 23, wherein the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises: a) hybridizing a probe or probe combination comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence or sequences to L. monocytogenes genomic DNA obtained from the sample; and b) detecting a hybridization product comprising the probe or probe combination and a L. monocytogenes genomic DNA sequence.
 32. The method of claim 25, wherein the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises: a) hybridizing a probe combination comprising i) a lineage I-specific nucleic acid sequence; ii) a sublineage I.2-specific nucleic acid sequence; iii) a lineage II-specific nucleic acid sequence; and iv) a sublineage II.1-specific nucleic acid sequence to L. monocytogenes genomic DNA obtained from the sample; and b) detecting a hybridization product comprising the probe or probe combination and a L. monocytogenes genomic DNA sequence.
 33. The method of claim 32, wherein the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.
 34. The method of claim 23, wherein the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises: a) hybridizing a primer or primer combination comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence or sequences to L. monocytogenes genomic DNA obtained from the sample; b) amplifying a L. monocytogenes sub-lineage-specific fragment or fragments with a polymerase; and c) detecting the L. monocytogenes sub-lineage-specific fragment or fragments.
 35. The method of claim 25, wherein the determining a L. monocytogenes sub-lineage-specific nucleic acid sequence combination for the L. monocytogenes in the sample comprises: a) hybridizing a primer or primer combination comprising i) a lineage I-specific nucleic acid sequence; ii) a sublineage I.2-specific nucleic acid sequence; iii) a lineage II-specific nucleic acid sequence; and iv) a sublineage II.1-specific nucleic acid sequence to L. monocytogenes genomic DNA obtained from the sample; and b) amplifying a L. monocytogenes sub-lineage-specific fragment or fragments with a polymerase; and c) detecting the L. monocytogenes sub-lineage-specific fragment or fragments.
 36. The method of claim 35, wherein the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.
 37. A hybridization support comprising a L. monocytogenes-specific nucleic acid sequence.
 38. The hybridization support of claim 37, wherein the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, plcA, actA, plcB, Imo206, inIA, inIB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, plcA, actA, plcB, Imo206, inIA, inIB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821.
 39. The hybridization support of claim 37, wherein the L. monocytogenes-specific nucleic acid sequence is inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.
 40. A hybridization support comprising a L. monocytogenes lineage-specific nucleic acid sequence.
 41. The hybridization support of claim 40, wherein the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF
 1761. 42. The hybridization support of claim 40, wherein the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence.
 43. The hybridization support of claim 42, wherein the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 44. The hybridization support of claim 40, wherein the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence.
 45. The hybridization support of claim 44, wherein the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 46. The hybridization support of claim 40, wherein the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence.
 47. The hybridization support of claim 46, wherein the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1 666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.
 48. A hybridization support comprising a L. monocytogenes sub-lineage-specific nucleic acid sequence combination.
 49. The hybridization support of claim 48, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises: a) a lineage I-specific nucleic acid sequence; b) a sublineage I.1- or I.2-specific nucleic acid sequence; c) a lineage II-specific nucleic acid sequence; and d) a sublineage II.1- or II.2-specific nucleic acid sequence.
 50. The hybridization support of claim 49, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence.
 51. The hybridization support of claim 50, wherein the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 52. The hybridization support of claim 50, wherein the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo118 or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119.
 53. The hybridization support of claim 50, wherein the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 54. The hybridization support of claim 50, wherein the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment or variant of ORF 0799, ORF 2372 or ORF
 2110. 55. The hybridization support of claim 50, wherein the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1 -specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.
 56. A kit for use in a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the kit comprises the isolated nucleic acid according to claim 1 in packaged form.
 57. A kit for use in a method for distinguishing between L. monocytogenes serovar 4b strain CLIP80459 and L. monocytogenes strain EGDe in a sample, wherein the kit comprises the hybridization support according to claim 2 in packaged form.
 58. A kit for use in a method for identifying a L. monocytogenes in a sample, wherein the kit comprises a hybridization support comprising a L. monocytogenes-specific nucleic acid sequence, in packaged form.
 59. The kit according to claim 58, wherein the L. monocytogenes-specific nucleic acid sequence is Imo0082, Imo0083, pIcA, actA, pIcB, Imo206, inIA, inIB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821; or a fragment or variant of Imo0082, Imo0083, pIcA, actA, pIcB, Imo206, inIA, inIB, Imo0440, Imo0638, Imo0733, Imo0833, Imo1133, Imo1135, Imo2732, Imo2733, Imo2734, Imo2736, Imo0017, Imo0094, inIH, inIE, Imo0333, Imo0549, Imo0832, Imo0834, Imo0835, Imo1441, Imo1451, or Imo2821.
 60. The kit according to claim 58, wherein the L. monocytogenes-specific nucleic acid sequence is inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0160, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo1115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029; or a fragment or variant of inIA, inIB, Imo2085, Imo1413, Imo0463, Imo0460, Imo0550, Imo0161, Imo0333, inIE, inIH, Imo2821, Imo2027, inIC, Imo0835, Imo1666, inIF, Imo320, Imo0842, Imo0801, inIG, Imo115, Imo2576, Imo0171, Imo2026, ORF2568, ORF1761, or ORF0029.
 61. A kit for use in a method for identifying the lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes lineage-specific nucleic acid sequence.
 62. The kit according to claim 61, wherein the L. monocytogenes lineage-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF 1761; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973, Imo1974, ORF 2819, ORF 3840, ORF 2568, ORF 0029 or ORF
 1761. 63. The kit according to claim 61, wherein the L. monocytogenes lineage is lineage I and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage I-specific nucleic acid sequence.
 64. The kit according to claim 63, wherein the L. monocytogenes lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 65. The kit according to claim 61, wherein the L. monocytogenes lineage is lineage II and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage II-specific nucleic acid sequence.
 66. The kit according to claim 65, wherein the L. monocytogenes lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 67. The kit according to claim 61, wherein the L. monocytogenes lineage is lineage III and the L. monocytogenes lineage-specific nucleic acid sequence is a L. monocytogenes lineage III-specific nucleic acid sequence.
 68. The kit according to claim 67, wherein the L. monocytogenes lineage III-specific nucleic acid sequence is Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671; or a fragment or variant of Imo1666, Imo0835, Imo0036, Imo0037, Imo0038, Imo0039, Imo0040, Imo0041, Imo94, Imo832, Imo1441, Imo1451, or Imo2671.
 69. A kit for use in a method for identifying the sub-lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes sub-lineage-specific nucleic acid sequence combination.
 70. The kit of claim 69, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises: a) a lineage I-specific nucleic acid sequence; b) a sublineage I.1- or I.2-specific nucleic acid sequence; c) a lineage II-specific nucleic acid sequence; and d) a sublineage II.1- or II.2-specific nucleic acid sequence.
 71. The kit of claim 70, wherein the L. monocytogenes sub-lineage-specific nucleic acid sequence combination comprises a sublineage I.2-specific nucleic acid sequence and a sublineage II.1-specific nucleic acid sequence.
 72. The kit of claim 71, wherein the lineage I-specific nucleic acid sequence is Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973or Imo1974; or a fragment or variant of Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo106l, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 or Imo1974.
 73. The kit of claim 71, wherein the sublineage I.2-specific nucleic acid sequence is Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119; or a fragment or variant of Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 or Imo1119.
 74. The kit of claim 71, wherein the lineage II-specific nucleic acid sequence is ORF 2819, ORF 3840, ORF 2568, ORF 29 or ORF 1761; or a fragment or variant of ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 75. The kit of claim 71, wherein the sublineage II.1-specific nucleic acid sequence is ORF 0799, ORF 2372 or ORF 2110; or a fragment of ORF 0799, ORF 2372 or ORF
 2110. 76. The kit of claim 71, wherein the lineage I-specific nucleic acid sequence is Imo737 or a fragment or variant thereof, the sublineage I.2-specific nucleic acid sequence is Imo1119 or a fragment or variant thereof, the lineage II-specific nucleic acid sequence is ORF 2819 or a fragment or variant thereof, and the sublineage II.1-specific nucleic acid sequence is ORF 2110 or a fragment or variant thereof.
 77. A hybridization support comprising a probe specific for L. monocytogenes EGDe relative to L. innocua CLIP11262, a probe specific for L. innocua CLIP11262 relative to L. monocytogenes EGDe, and a probe present only in L. monocytogenes CLIP80459.
 78. The hybridization support of claim 77, wherein the hybridization support comprises 262 probes specific for L. monocytogenes EGDe relative to L. innocua CLIP11262 and all virulence genes, 94 probes specific for L. innocua CLIP11262 relative to L. monocytogenes EGDe, and 53 probes present only in L. monocytogenes CLIP80459.
 79. The hybridization support of claim 77, wherein the hybridization support comprises the 409 probes listed in Table 7, or fragments or variants thereof.
 80. The hybridization support of claim 77, wherein the hybridization support comprises the 192 probes listed in Table 16, or fragments or variants thereof.
 81. A method of serotyping a L. monocytogenes, wherein the method comprises: a) providing a sample comprising an L. monocytogenes of unknown serotype; b) providing an amplification primer pair for amplification of a 1/2a-1/2c-specific nucleic acid sequence; c) providing an amplification primer pair for amplification of a 1/2b-4b-specific nucleic acid sequence; d) providing an amplification primer pair for amplification of a 1/2c nucleic acid sequence; e) providing an amplification primer pair for amplification of a 4b nucleic acid sequence; e) performing an amplification reaction on the sample; and f) detecting the presence of any amplification products formed during the amplification reaction to thereby serotype the L. monocytogenes.
 82. The method of claim 81, wherein the 1/2a-1/2c-specific nucleic acid sequence is selected from Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo106l, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 and Imo1974.
 83. The method of claim 82, wherein the 1/2a-1/2c-specific nucleic acid sequence is Imo737.
 84. The method of claim 81, wherein the 1/2b-4b-specific nucleic acid sequence is selected from ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 85. The method of claim 84, wherein the 1/2b-4b-specific nucleic acid sequence is ORF
 2819. 86. The method of claim 81, wherein the 1/2c nucleic acid sequence is selected from Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 and Imo1119.
 87. The method of claim 86, wherein the 1/2c nucleic acid sequence is Imo1119.
 88. The method of claim 81, wherein the 4b nucleic acid sequence is selected from ORF 799, ORF 2372 and ORF
 2110. 89. The method of claim 81, wherein the 4b nucleic acid sequence is ORF
 2110. 90. The method of claim 81, wherein the 1/2a-1/2c-specific nucleic acid sequence is Imo737, the 1/2b-4b-specific nucleic acid sequence is ORF 2819, the 1/2c nucleic acid sequence is Imo1119, and the 4b nucleic acid sequence is ORF
 2110. 91. A kit for use in serotyping a L. monocytogenes , wherein the kit comprises: a) an amplification primer pair for amplification of a 1/2a-1/2c-specific nucleic acid sequence; b) an amplification primer pair for amplification of a 1/2b-4b-specific nucleic acid sequence; d) an amplification primer pair for amplification of a 1/2c nucleic acid sequence; and e) an amplification primer pair for amplification of a 4b nucleic acid sequence.
 92. The kit of claim 91, wherein the 1/2a-1/2c-specific nucleic acid sequence is selected from Imo171, Imo172, Imo525, Imo734, Imo735, Imo736, Imo737, Imo738, Imo739, Imo1060, Imo1061, Imo1062, Imo1063, Imo1968, Imo1969, Imo1970, Imo1971, Imo1973 and Imo1974.
 93. The kit of claim 92, wherein the 1/2a-1/2c-specific nucleic acid sequence is Imo737.
 94. The kit of claim 91, wherein the 1/2b-4b-specific nucleic acid sequence is selected from ORF 2819, ORF 3840, ORF 2568, ORF 29 and ORF
 1761. 95. The kit of claim 94, wherein the 1/2b-4b-specific nucleic acid sequence is ORF
 2819. 96. The kit of claim 91, wherein the 1/2c nucleic acid sequence is selected from Imo151, Imo466, Imo467, Imo469, Imo470, Imo471, Imo1118 and Imo1119.
 97. The kit of claim 96, wherein the 1/2c nucleic acid sequence is Imo1119.
 98. The kit of claim 91, wherein the 4b nucleic acid sequence is selected from ORF 799, ORF 2372 and ORF
 2110. 99. The kit of claim 91, wherein the 4b nucleic acid sequence is ORF
 2110. 100. The kit of claim 91, wherein the 1/2a-1/2c-specific nucleic acid sequence is Imo737, the 1/2b-4b-specific nucleic acid sequence is ORF 2819, the 1/2c nucleic acid sequence is Imo1119, and the 4b nucleic acid sequence is ORF
 2110. 101. A method for sub-lineage typing of a L. monocytogenes in a sample, wherein the method comprises detecting the absence or presence of L. monocytogenes sub-lineage specific nucleic acid sequence in the sample.
 102. The method of claim 101, wherein the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence.
 103. The method of claim 102, wherein the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.
 104. A hybridization support comprising a L. monocytogenes sub-lineage specific nucleic acid sequence.
 105. The hybridization support of claim 104, wherein the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence.
 106. The hybridization support of claim 105, wherein the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.
 107. A kit for use in a method for identifying the lineage of a L. monocytogenes in a sample, wherein the kit comprises a L. monocytogenes sub-lineage specific nucleic acid sequence.
 108. The kit according to claim 107, wherein the L. monocytogenes sub-lineage specific nucleic acid sequence is a L. monocytogenes sub-lineage II.1 specific nucleic acid sequence.
 109. The kit according to claim 108, wherein the L. monocytogenes sub-lineage II.1 specific nucleic acid sequence is ORF0799, ORF2372, or ORF2110; or a fragment or variant of ORF0799, ORF2372, or ORF2110.
 110. A method of designing a hybridization support for typing Listeria, wherein the method comprises: a) determining at least one combination of Listeria species, strains, lineages, or sublineages to be distinguished; and b) selecting a plurality of probes from Table 17, based on the data presented in Table 17, for inclusion in the hybridization support. 